CN108635249B

CN108635249B - Hydrogel-based basal facial mask composition and preparation method thereof

Info

Publication number: CN108635249B
Application number: CN201810474485.6A
Authority: CN
Inventors: 汪建新; 陈太军; 朱树凯; 彭文珍
Original assignee: Chengdu Yikeda Biotechnology Co ltd
Current assignee: Chengdu Yikeda Biotechnology Co ltd
Priority date: 2018-05-17
Filing date: 2018-05-17
Publication date: 2021-04-13
Anticipated expiration: 2038-05-17
Also published as: CN108635249A

Abstract

The invention discloses a hydrogel substrate mask composition which comprises, by weight, 10-33 parts of polyglutamic acid, 8-30 parts of lysine, 1-5 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 1-5 parts of N-hydroxysuccinimide, 1-3 parts of organic silicon, 5-10 parts of chitosan fiber and 2-14 parts of functional components. The hydrogel substrate facial mask prepared by the invention mainly contains polyglutamic acid, lysine, organic silicon, chitosan fiber, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, N-hydroxysuccinimide and functional components, and the facial mask prepared by the reaction of the components has the functions of efficient whitening, moisturizing, bacteriostasis and ultraviolet ray defense.

Description

Hydrogel-based basal facial mask composition and preparation method thereof

Technical Field

The invention relates to the technical field of daily chemical products, in particular to a hydrogel-based bottom film composition and a preparation method thereof.

Background

Among beauty cosmetics, facial masks are one of the earliest. The facial mask temporarily isolates outside air and pollution by covering the facial mask on the face for a short time, the skin temperature is increased, pores of the skin are expanded, secretion and metabolism of sweat glands are promoted, the oxygen content of the skin is increased, products of metabolism of epidermal cells and accumulated grease substances are favorably removed from the skin, moisture in the facial mask permeates into the cuticle of the epidermis, the skin becomes soft, and the skin is naturally bright and elastic. Therefore, the facial mask becomes one of the most popular skin care products for women.

The traditional patch type facial mask adopts non-woven fabrics and cotton cloth or silk as a substrate to absorb essence, but the traditional facial mask has the defects of poor affinity with skin, poor thickness, poor air permeability, less absorbed essence after the facial mask is attached, high cost of the silk facial mask and the like.

Disclosure of Invention

The invention provides a hydrogel-based bottom surface film composition and a preparation method thereof, which are used for solving the technical problems in the prior art and are realized by the following technical scheme: 10-33 parts of polyglutamic acid, 8-30 parts of lysine, 1-5 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 1-5 parts of N-hydroxysuccinimide, 1-3 parts of organosilicon, 5-10 parts of chitosan fiber and 2-14 parts of functional components by weight.

In order to better realize the invention, the chitosan fiber-modified starch further comprises, by weight, 12-20 parts of polyglutamic acid, 15-25 parts of lysine, 2-3 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 2-3 parts of N-hydroxysuccinimide, 2 parts of organosilicon, 6-9 parts of chitosan fiber and 4-6 parts of a functional component.

In order to better implement the invention, further, the organic silicon comprises one or more of dimethyl polysiloxane, methyl phenyl polysiloxane, cyclic polysiloxane and silicone oil.

In order to better implement the invention, the functional components are hyaluronic acid, glycerin, butanediol, ceramide, allantoin, mineral elements, amino acids and collagen, and the functional components become moisturizing.

In order to better implement the invention, the functional components are ascorbic acid and derivatives thereof, nicotinamide, kojic acid, tranexamic acid and fruit liquorice extract, and the components are whitening.

In order to better implement the invention, the functional components include retinol and derivatives thereof, vitronectin and soybean isoflavone, and the components are anti-aging substances.

In order to better implement the invention, the functional components are hydroxy acid, salicylic acid, benzoyl peroxide and azalea acid, and the components are anti-acne.

The invention also provides a preparation method of the hydrogel substrate mask, which comprises the following steps:

s1: dissolving polyglutamic acid and lysine in deionized water, and stirring continuously to prepare a solution A;

s2: blending organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 20-50 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain solution B;

s3: mixing the solution A and the solution B, adding 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxysuccinimide, continuously stirring, and adjusting the pH value to prepare a solution C;

s5: and adding the functional components into the solution C, fully reacting, injecting the solution C into a mask mold, carrying out gel forming in the mold, and taking out to obtain the hydrogel substrate mask.

To better implement the present invention, further, the step S2: and (3) blending the organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 30-35 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain a solution B.

To better implement the present invention, further, the step S2: and (3) blending the organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 32 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain a solution B.

The embodiment of the invention has the beneficial effects that:

the hydrogel substrate facial mask prepared by the invention mainly contains polyglutamic acid, lysine, organic silicon, chitosan fiber, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, N-hydroxysuccinimide and functional components, and the facial mask prepared by the reaction of the components has the functions of efficient whitening, moisturizing, bacteriostasis and ultraviolet ray defense.

In the process of developing the facial mask, the facial mask containing polyglutamic acid and lysine components has strong moisturizing and ultraviolet ray defending effects, researchers find through long-term and continuous efforts that the polyglutamic acid is a biodegradable polyamino acid compound which is prepared by fermentation of bacillus and has good biocompatibility and no toxicity to human beings, and the side group of the polyglutamic acid is a carboxyl group which is formed by condensation of D-glutamic acid and L-glutamic acid and has high activity.

The polyglutamic acid acts on the skin, so that the content of main components can be greatly increased, the main components of the polyglutamic acid can directly induce the self-generation of natural moisturizing factors in the skin, the deep moisturizing capability of the skin is enhanced, and in the composite molecular structure of the polyglutamic acid, one hundred million molecular weight ultrahigh molecules form a protective film on the surface layer of the skin, so that not only can the water loss and the ultraviolet ray be prevented, but also the opportunity of breeding bacteria in the skin can be greatly reduced.

Therefore, the moisturizing effect of the polyglutamic acid is quite strong, the polyglutamic acid mainly contains the characteristics of combination of ultra-low molecules and ultra-high molecules, the ultra-high molecules can form a layer of strong protective film on the outer layer of the skin, and the ultra-low molecules carry corresponding functional components to penetrate into the skin to nourish and moisten the deep layer of the skin.

According to research, the main reason for generating the effect is that the hydrogel mask only containing polyglutamic acid and lysine is prepared, the components are unstable, the coagulation phenomenon between the components is poor, the action time of the hydrogel mask on the skin is short, the effect is poor, and the molecular action cohesion between the polyglutamic acid and the lysine is enhanced through the cooperative operation of the organosilicon and the chitosan fiber, so that the effective components on the skin applied by the hydrogel substrate mask can be effectively released in a certain time, and the effects of whitening, moisturizing, defending and bacteriostasis of the hydrogel substrate mask are further ensured.

Researches of researchers find that a small amount of organic silicon and chitosan fibers are added into the polyglutamic acid hydrogel substrate facial mask, so that the cohesive force of the polyglutamic acid and lysine can be increased, and heavy metals on the surface of the skin can be effectively adsorbed, mainly because the polyglutamic acid, the lysine, the organic silicon and the chitosan fibers have synergistic effect, the heavy metals on the surface of the skin can be adsorbed and carried out, the skin of the skin is cleaner, and the moisturizing effect of the prepared hydrogel substrate facial mask is more obvious.

Compared with the existing facial masks in the market, particularly the facial masks of vegetable, animal and mineral oil, the three facial masks prevent water from volatilizing through a protective film formed on the surface of skin by the formation of oil, but are easy to block pores.

In the preparation method process of the present invention, it is important to control the temperature well in step S2, because too high temperature may decrease the viscosity of the chitosan fiber, thereby affecting the characteristics of the whole hydrogel base mask, and long-term experiments show that the temperature is best when controlled at 32 ℃.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments.

All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1:

a hydrogel substrate mask composition comprises, by weight, 10 parts of polyglutamic acid, 8 parts of lysine, 1 part of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 1 part of N-hydroxysuccinimide, 1 part of silicone, 5 parts of chitosan fiber and 2 parts of functional components;

the preparation method of the hydrogel basal bottom membrane comprises the following steps:

s2: blending organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 20 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain solution B;

Example 2:

a hydrogel substrate facial mask composition comprises, by weight, 33 parts of polyglutamic acid, 30 parts of lysine, 5 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 5 parts of N-hydroxysuccinimide, 3 parts of silicone, 10 parts of chitosan fiber and 14 parts of functional components;

s2: blending organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 50 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain solution B;

Example 3:

a hydrogel substrate facial mask composition comprises, by weight, 12 parts of polyglutamic acid, 15 parts of lysine, 2 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 2 parts of N-hydroxysuccinimide, 2 parts of silicone, 6 parts of chitosan fiber and 4 parts of functional components;

s2: blending organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 30 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain solution B;

Example 4:

a hydrogel substrate facial mask composition comprises, by weight, 20 parts of polyglutamic acid, 25 parts of lysine, 3 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 3 parts of N-hydroxysuccinimide, 2 parts of silicone, 9 parts of chitosan fiber and 4 parts of functional components;

Example 5:

a hydrogel substrate facial mask composition comprises, by weight, 18 parts of polyglutamic acid, 20 parts of lysine, 2 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 3 parts of N-hydroxysuccinimide, 3 parts of organosilicon, 8 parts of chitosan fiber and 5 parts of functional components;

s2: blending organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 32 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain solution B;

Example 6:

a hydrogel substrate facial mask composition comprises, by weight, 25 parts of polyglutamic acid, 10 parts of lysine, 1 part of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 5 parts of N-hydroxysuccinimide, 1 part of silicone, 8 parts of chitosan fiber and 10 parts of functional components;

s2: blending organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 40 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain solution B;

Comparative example 1:

a hydrogel substrate mask composition comprises, by weight, 5 parts of polyglutamic acid, 4 parts of lysine, 1 part of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 1 part of N-hydroxysuccinimide, 1 part of silicone, 2 parts of chitosan fiber and 1 part of a functional component;

s2: blending organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 10 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain solution B;

Comparative example 2:

a hydrogel substrate facial mask composition comprises, by weight, 45 parts of polyglutamic acid, 40 parts of lysine, 9 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 10 parts of N-hydroxysuccinimide, 20 parts of silicone, 20 parts of chitosan fiber and 20 parts of functional components;

s2: blending organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 45 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain solution B;

Comparative example 3:

a hydrogel substrate facial mask composition comprises, by weight, 15 parts of polyglutamic acid, 15 parts of lysine and 10 parts of functional components;

s5: adding the functional components into the solution A, fully reacting, injecting the solution A into a mask mold, carrying out gel forming in the mold, and taking out to obtain the hydrogel substrate mask.

The experimental results are as follows:

the above examples and comparative examples were subjected to skin moisture loss, gel strength comparison, and feeling of use measurement.

Skin moisture loss measurement 90 women are selected and divided into 9 groups, the facial masks prepared in the examples and the comparative examples are respectively applied on the face for 15-25 minutes, and then the measurement results show that the facial masks suck back 1-3 times, the moisture loss speed is high in 4-6 times, the moisture loss speed is normal in 7-9 times, and the moisture loss speed is low in 10 times.

Gel strength measurement 90 women were selected and divided into 9 groups, and the masks prepared in examples and comparative examples were placed in a constant temperature bath at room temperature, 4 ℃ and 30 ℃ to measure the change in gel strength, and compared with the standard, and the gel strength was divided into 1 to 3 more separations, 4 to 6 slightly more separations, 7 to 9 few separations, and 10 no separations.

The using feeling determination is to select 90 women, divide into 9 groups, apply the facial masks prepared in the experimental example and the comparative example on the face for 15 minutes respectively, then determine the using feeling, and the evaluation is expressed as 1-3 as poor; 4 to 6 are common, 7 to 9 are good, and 10 is good.

Table 1:

	loss of skin moisture	Gel strength	Feeling of use
				Experimental example 1	6	5	4
Experimental example 2	8	7	7
				Experimental example 3	7	8	10
Experimental example 4	9	10	9
				Experimental example 5	10	9	8
Experimental example 6	8	7	9
				Comparative example 1	1	1	1
Comparative example 2	2	1	1
				Comparative example 3	3	2	1

In summary, the following steps: the hydrogel substrate facial mask prepared by the invention has the effects of moisturizing, bacteriostasis and the like, and in the comparison process of the embodiment and the comparative example, the facial mask of the embodiment is obviously stronger than the comparative example in skin moisturizing, gel strength and use feeling.

While embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A hydrogel-based bottom film composition characterized by: the functional chitosan fiber is prepared from the following components, by weight, 10-33 parts of polyglutamic acid, 8-30 parts of lysine, 1-5 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 1-5 parts of N-hydroxysuccinimide, 1-3 parts of silicone, 5-10 parts of chitosan fiber and 4-14 parts of a functional component.

2. The hydrogel based bottom surface film composition of claim 1, wherein: the chitosan fiber is prepared from the following components, by weight, 12-20 parts of polyglutamic acid, 15-25 parts of lysine, 2-3 parts of 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride, 2-3 parts of N-hydroxysuccinimide, 2 parts of silicone, 6-9 parts of chitosan fiber and 4-6 parts of a functional component.

3. The hydrogel based bottom surface film composition of claim 1, wherein: the organic silicon comprises one or more of dimethyl polysiloxane, methyl phenyl polysiloxane and cyclic polysiloxane.

4. The hydrogel substrate mask composition according to any one of claims 1 to 3, wherein: the functional components comprise hyaluronic acid, glycerol, butanediol, ceramide, allantoin, mineral elements, amino acids and collagen.

5. The hydrogel substrate mask composition according to any one of claims 1 to 3, wherein: the functional components are ascorbic acid and derivatives thereof, nicotinamide, kojic acid and tranexamic acid.

6. The hydrogel substrate mask composition according to any one of claims 1 to 3, wherein: the functional components are retinol and derivatives thereof, vitronectin and soybean isoflavone.

7. The hydrogel substrate mask composition according to any one of claims 1 to 3, wherein: the functional components are hydroxy acid, salicylic acid, benzoyl peroxide and azalea acid.

8. A method of making a hydrogel substrate mask composition as defined in any one of claims 1 to 7 wherein: the method comprises the following steps:

9. The method of making a hydrogel substrate mask composition of claim 8, wherein: the step S2: and (3) blending the organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 30-35 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain a solution B.

10. The method of making a hydrogel substrate mask composition of claim 9, wherein: the step S2: and (3) blending the organic silicon into emulsion, adding chitosan fiber into the emulsion, controlling the temperature at 32 ℃, stirring, fully reacting, and standing for 20-60 minutes to obtain a solution B.