CN108619394A - A kind of composition of strengthen immunity and application thereof - Google Patents
A kind of composition of strengthen immunity and application thereof Download PDFInfo
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- CN108619394A CN108619394A CN201710184751.7A CN201710184751A CN108619394A CN 108619394 A CN108619394 A CN 108619394A CN 201710184751 A CN201710184751 A CN 201710184751A CN 108619394 A CN108619394 A CN 108619394A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention belongs to pharmaceutical technology fields, more particularly to a kind of composition of strengthen immunity and application thereof, the composition has the effect of significantly increasing body immunity, especially to causing the patient of hypoimmunity that there is preferable immunity adjustment effect because of cancer stricken or because for the treatment of of cancer, it can be used for the auxiliary treatment of cancer patient.
Description
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of composition and its use for enhancing human immunity
On the way, the composition has the effect of significantly increasing body immunity, especially to causing to be immunized because of cancer stricken or because for the treatment of of cancer
The low patient of power has preferable immunity adjustment effect, can be used for the auxiliary treatment of cancer patient.
Background technology
Immunity is the defense mechanism of human body itself, is any foreign matter of human bioequivalence and the external intrusion of elimination（It is viral, thin
Bacterium etc.）, processing aging, damage, death, the own cells of denaturation and identification and processing vivo mutations cell and virus infection are carefully
The ability of born of the same parents.The people of hypoimmunity resists the energy force difference of external environment undesirable element because of itself, is prone to infect various thin
Bacterium and virus, cause body easily fall ill or disease hair after be not cured for a long time, the physical function of patient is generated and is further damaged, from
And patient's immunity is reduced, vicious circle is formed, major disease etc. is induced.
Possess the infringement that good immunity is to ensure that human body from disease, possess healthy body, keeps vigorous energy
Basis, but due to life and disease reason, the immunity of most people have different degrees of reduction, and it is strong to its body
Health has an adverse effect.Wherein life reason include mainly：Work and life stress are big, psychological stress, fatigue, diet lose
The reasons such as weigh, do not get enough athletic exercise are easy to cause immunity degradation；Disease reason includes mainly：Due to suffering from major disease, for a long time not
More, when body being caused to consume or be used for a long time for a long time certain drug or carry out disease treatment using particular treatment mode, continuous shadow
Ring and reduce body immunity, such as cancer patient.Cancer is mainly characterized by cancer cell ceaselessly hyperplasia and migration, constantly disappears
The a large amount of nutriment of patient's body is consumed, while discharging a variety of toxin, causes human body to be become thin, inability, anaemia, loss of appetite, hair
Hot and serious organ function is impaired etc.；Cancer is treated frequently with the mode of chemotherapy, although which can kill greatly
Part cancer cell, but it is also larger to the injury of self immune system simultaneously, patient's immunity can be further decreased, and then accelerate cancer
There is whole body fatigue and weak in cellular invasion, and apathetic, cold perspiration is drowsiness etc..Therefore, human body especially cancer how is improved
The immunity of patient is medical personal and patient's concern the most a few days ago.
There are many methods that can improve immunity at present, wherein commonly using easy mode mainly has：It improves through diet
The immunity of body, including the regular edible food rich in protein, polysaccharide, amino acid needed by human and trace element
Object；Immunity of organisms is improved by taking nourishing class drug, such as takes cordyceps sinensis, ginseng, the expensive detail medicine of propolis for a long time；It is logical
Cross the modes such as physical therapy and reconcile immunity of organisms, such as treat by acupuncture and moxibustion, acupoint therapy, massage, scraping；It is carried by physical training
High immunity of organisms, such as running, swimming.For immunocompromised patients caused by life reason, above-mentioned enhancing or conciliation are exempted from
The method of epidemic disease power is each advantageous and insufficient, immunity can be adjusted and be enhanced to a certain extent by the above method.
But to because of disease reason, especially suffering from cancer and leading to immunocompromised person, the above method is slow because of poor operability, effect
The reasons such as slowly, adverse reaction is apparent and there is larger limitation, therefore, finding a kind of can safely and effectively improve tumor patient
Immunity mitigates side effect when tumor patient treatment, improves the composition of Quality of Life of Patients with Tumor and becomes clinical treatment cancer
The active demand of disease.
For the above situation, inventor is guidance with traditional Chinese medicine theory, in conjunction with many decades clinical research and use
Medicine experience, based on to body immunity regulation mechanism understanding and analysis, optimize and adjust formula repeatedly, it is final to obtain the present invention
Pharmaceutical composition, and enhancing human immunity especially in terms of enhancing cancer patient's immunity, achieving unexpected
Effect.
Invention content
Technical problem to be solved by the invention is to provide one kind to suffer from for enhancing human immunity especially enhancing cancer
The composition of person's immunity.
Another technical problem to be solved by this invention is to propose that the composition is enhancing human immunity especially cancer
Purposes in terms of patient's immunity.
The specific technical solution of the present invention is as follows：
The present invention provides a kind of composition of strengthen immunity, which is characterized in that in parts by weight, by following substance group
At：1-30 parts of Rosa roxburghii Tratt, 1-30 parts of emblic, 0.5-25 parts of pomegranate, 0.5-25 parts of honey, 0.1-20 parts of mangosteen, coconut 0.1-20
Part, 0.1-20 parts of lemon, 0.1-20 parts of walnut, 0.01-10 parts of Rhizoma Gastrodiae, 0.01-10 parts of ganoderma lucidum, 0.01-10 parts of moringa seeds.
Preferably, the composition, which is characterized in that in parts by weight, by following material composition：Rosa roxburghii Tratt 1-
20 parts, 1-20 parts of emblic, 0.5-20 parts of pomegranate, 0.5-20 parts of honey, 0.1-15 parts of mangosteen, 0.1-15 parts of coconut, lemon
0.1-15 parts, 0.1-15 parts of walnut, 0.1-10 parts of Rhizoma Gastrodiae, 0.1-10 parts of ganoderma lucidum, 0.1-10 parts of moringa seeds.
Preferably, the composition, which is characterized in that in parts by weight, by following material composition：Rosa roxburghii Tratt 5-
15 parts, 5-15 parts of emblic, 1-15 parts of pomegranate, 1-15 parts of honey, 1-15 parts of mangosteen, 1-15 parts of coconut, 1-15 parts of lemon, walnut
1-15 parts, 0.1-5 parts of Rhizoma Gastrodiae, 0.1-5 parts of ganoderma lucidum, 0.1-5 parts of moringa seeds.
The present invention provides the preparation method of the composition and dosage forms, which is characterized in that the Chinese medicine composition
Preparation method is that the substance is taken to be prepared into powder through one or more methods in crushing, decoction, alcohol extracting, immersion, diacolation, fermentation
After end, solution or clear cream, oral preparation is prepared into using conventional formulation means.
Preferably, the dosage form of composition of the present invention be tablet, granule, capsule, oral solution, syrup, pill,
Paste, medicinal tea etc..
The present invention provides the purposes of the composition, i.e.,：Being enhanced human immunity in preparation especially enhances cancer
Application in the drug of patient's immunity, health food and food.
Beneficial effects of the present invention are：
1) present composition is for when enhancing human immunity especially cancer patient's immunity, significant effect can be used extensively
The auxiliary treatment of hypoimmunity disease and cancer patient caused by many reasons mitigates the pain of patient significantly, improves patient
Quality of life；The benefits of also Johnson ＆ Johnson is healthy and strong simultaneously.
2) all pure natural Chinese herbal medicines of composition material therefor provided by the invention or food, have it is green and healthy, make
With safety, the features such as having no toxic side effect；The composition material therefor derives from a wealth of sources, cheap, and production cost is low, can subtract significantly
The financial burden of light patient and its family.
3) composition preparation process provided by the invention is simple, easy to use, is easy to be eaten for a long time, good using compliance,
With extensive clinical application.
Specific implementation mode
With reference to embodiment, present disclosure is further illustrated.It should be appreciated that the implementation of the present invention is not limited to
In the following examples, the accommodation in any form and/or change made to the present invention fall within the scope of the present invention.
In the present invention, if not refering in particular to, all parts, percentage are unit of weight.Method in following embodiments, such as
It is the conventional method of this field without special instruction；In the present invention, the botanical or food materials can be fresh goods,
It can be the dry product after cutting, drying.
Embodiment 1：Rosa roxburghii Tratt 30g, emblic 30g, pomegranate 25g, mangosteen 20g, coconut 20g, lemon 20g, walnut 20g are taken,
The water of 6 times of above-mentioned prescription total weight is added in Rhizoma Gastrodiae 10g, ganoderma lucidum 10g, moringa seeds 9g, impregnates half an hour, decocts 2 times, 2 is small every time
When, filtering, merge liquid, be added honey 20g, mixing to get.
Embodiment 2：Take Rosa roxburghii Tratt 1g, emblic 1g, pomegranate 0.5g, mangosteen 0.5g, coconut 0.1g, lemon 0.1g, walnut
0.5g, Rhizoma Gastrodiae 0.05g, ganoderma lucidum 0.02g, moringa seeds 0.2g are ground into coarse powder, are distributed into tea bag, and honey 1g is added when brewing,
To obtain the final product.
Embodiment 3：Take Rosa roxburghii Tratt 27g, emblic 27g, pomegranate 27g, mangosteen 15g, coconut 15g, lemon 15g, walnut
The water of 3 times of above-mentioned prescription total weight is added in 15g, Rhizoma Gastrodiae 3g, ganoderma lucidum 3g, moringa seeds leaf 3g, sealing, sets shady place and ferments 3
Month, filtering, be added honey 27g, mixing to get.
Embodiment 4：Take Rosa roxburghii Tratt 10g, emblic 10g, pomegranate 10g, mangosteen 5g, coconut 5g, lemon 5g, walnut 2g, Rhizoma Gastrodiae
1g, ganoderma lucidum 1g, moringa seeds 1g, are ground into coarse powder, are infiltrated with 50% ethyl alcohol, and carry out seepage pressure effects with the flow velocity of 2ml/min,
Collect 3 times of prescription weight percolate, be added honey 10g, mixing to get.
Embodiment 5：Take Rosa roxburghii Tratt 20g, emblic 10g, pomegranate 5g, mangosteen 5g, coconut 5g, lemon 5g, walnut 10g, Rhizoma Gastrodiae
The water of 6 times of medicinal material total weight is added in 3g, ganoderma lucidum 3g, moringa seeds 1g, impregnates half an hour, extracts 2 times, 1.5 hours every time, filters,
Merge extracting solution, it is 1.1 ~ 1.2g/ml to be concentrated into relative density（60℃）, medicinal extract is obtained, honey 10g and appropriate is added into medicinal extract
Auxiliary material granulation, it is dry after, be distributed into granule or be pressed into tablet or filling at capsule to get.
Embodiment 6：Take Rosa roxburghii Tratt 25g, emblic 30g, pomegranate 15g, mangosteen 10g, coconut 15g, lemon 10g, walnut 5g,
The water of 3 times of above-mentioned prescription total weight is added in Rhizoma Gastrodiae 6g, ganoderma lucidum 3g, moringa seeds leaf 1g, sealing, sets shady place and ferments 2 months, mistake
Filter, be added honey 30g, mixing to get.
Embodiment 7：Take Rosa roxburghii Tratt 15g, emblic 10g, pomegranate 10g, mangosteen 6g, coconut 6g, lemon 6g, walnut 10g, Rhizoma Gastrodiae
3g, ganoderma lucidum 1.5g, moringa seeds 0.5g are ground into fine powder, are added honey 10g, pill to get.
Embodiment 8：Take Rosa roxburghii Tratt 27g, emblic 21g, pomegranate 9g, mangosteen 9g, coconut 6g, lemon 6g, walnut 10g, Rhizoma Gastrodiae
The water of 6 times of medicinal material total weight is added in 5g, ganoderma lucidum 3g, moringa seeds 0.5g, impregnates half an hour, extracts 2 times, 2 hours every time, filters,
Merge extracting solution, it is 1.1 ~ 1.2g/ml to be concentrated into relative density（60℃）, medicinal extract is obtained, honey 10g and appropriate is added into medicinal extract
Simple syrup is prepared into syrup, be distributed into 100ml/ bottles to get.
Embodiment 9：Take Rosa roxburghii Tratt 25kg, emblic 30kg, pomegranate 20kg, mangosteen 15kg, coconut 20kg, lemon 20kg, core
The water of 5 times of above-mentioned prescription total weight is added in peach 10kg, Rhizoma Gastrodiae 10kg, ganoderma lucidum 5kg, moringa seeds 6kg, impregnates half an hour, decocts 2
It is secondary, 2 hours every time, filtering, merge liquid, be added honey 25kg, mixing, be distributed into 100ml/ bottles to get.
Embodiment 10：Take Rosa roxburghii Tratt 30kg, emblic 24kg, pomegranate 24kg, mangosteen 20kg, coconut 15kg, lemon 15kg,
The water of 3 times of above-mentioned prescription total weight is added in walnut 12kg, Rhizoma Gastrodiae 6kg, ganoderma lucidum 3kg, moringa seeds leaf 5kg, and shady place is set in sealing
Fermentation 3 months, filtering, be added honey 25kg, mixing, be distributed into 100ml/ bottles to get.
Embodiment 11：Take Rosa roxburghii Tratt 18kg, emblic 12kg, pomegranate 10kg, mangosteen 6kg, coconut 9kg, lemon 5kg, walnut
3kg, Rhizoma Gastrodiae 1.5kg, ganoderma lucidum 1.5kg, moringa seeds 0.5kg, are ground into coarse powder, are infiltrated with 50% ethyl alcohol, and with 2ml/min's
Flow velocity carries out seepage pressure effects, collects the percolate of 3 times of prescription weight, and honey 12kg is added, and mixing is distributed into 100ml/ bottles, i.e.,
.
Embodiment 12：Take Rosa roxburghii Tratt 27kg, emblic 10kg, pomegranate 15kg, mangosteen 12kg, coconut 5kg, lemon 5kg, walnut
The water of 6 times of medicinal material total weight is added in 12kg, Rhizoma Gastrodiae 9kg, ganoderma lucidum 3kg, moringa seeds 3kg, impregnates half an hour, extracts 2 times, and every time 2
Hour, filtering merges extracting solution, and it is 1.1 ~ 1.2g/ml to be concentrated into relative density（60℃）, medicinal extract is obtained, bee is added into medicinal extract
Sweet 15kg and appropriate amount of auxiliary materials granulation, it is dry after, packing or tabletting or capsule charge to get.
Embodiment 13：Take Rosa roxburghii Tratt 25kg, emblic 20kg, pomegranate 18kg, mangosteen 15kg, coconut 12kg, lemon 12kg,
The water of 3 times of above-mentioned prescription total weight is added in walnut 6kg, Rhizoma Gastrodiae 5kg, ganoderma lucidum 3kg, moringa seeds leaf 2kg, honey 27kg, sealing,
Set shady place ferment 3 months, filtering, be distributed into 100ml/ bottles to get.
Embodiment 14：The composition Clinical practice effect of the present invention
1. clinical observation object
Observe case 322 altogether from June, 2005 to 2 months 2017, the age is between 18~76 years old.
（1）Physical examination is without exception, but flu is constantly throughout the year or flu is difficult to cured person：Observation 35, wherein male 14,
Women 21.
（2）Physical examination is without exception, but apathetic, the physically weak weak person of self-induction throughout the year, drowsiness or sleep person of not recovering from fatigue：Observation 28
Example, wherein male 18, women 10.
（3）Physical examination is without exception but long-term poor sleep, often insomnia, dreaminess or bad dream person：Observation 47, wherein male 21
Example, women 26.
（4）Cancer is suffered from, build is become thin, and physically weak weak, anaemia, fever, easily sends out the infected at loss of appetite：Observation 113
Example, wherein 61, women 52.
（5）Cancer is suffered from, occurs whole body fatigue and weak after tumor resection on hand and/or chemotherapy, it is apathetic, go out void
Sweat, drowsiness, anorexia, apocleisis, nausea and vomiting, the corners of the mouth generate bleb, the reduction of haemocyte and de- originator：Observation 99,
In 53, women 46.
2. therapy and criterion
It is confirmed as immunocompromised person after diagnosing, gives this composition, continuously takes three courses for the treatment of, each course for the treatment of 21 days, daily
It takes three times.Effect judges：Clinical manifestation is all eliminated and follow-up half a year non-recidivist is recovery from illness；Eliminate 60% or more and follow-up
Half a year non-recidivist is effective；Though eliminating 40% or more and follow-up half a year has recurrence but alleviator is effective earlier above；Other is nothing
Effect；Died is considered as the case that falls off in therapeutic process, is not included in statistics.
3. treatment results
（1）Physical examination is without exception, but flu is constantly throughout the year or flu is difficult to cured person：Recovery from illness 20, accounts for 57%；It effective 11, accounts for
31%；Effective 3, account for 9%：Invalid 1, account for 3%.
（2）Physical examination is without exception, but apathetic, the physically weak weak person of self-induction throughout the year, drowsiness or sleep person of not recovering from fatigue：Recovery from illness 17
Example, accounts for 61%；Effective 8, account for 28%；Effective 3, account for 11%：Invalid 0.
（3）Physical examination is without exception but long-term poor sleep, often insomnia, dreaminess or bad dream person：Recovery from illness 29, accounts for 62%；It is effective
11, account for 23%；Effective 7, account for 15%：Invalid 0.
（4）Cancer is suffered from, build is become thin, and physically weak weak, anaemia, fever, easily sends out the infected at loss of appetite：Recovery from illness 79,
Account for 76%；Effective 18, account for 17%；Effective 5, account for 5%：Invalid 2, account for 2%.Cause death falls off 9.
（5）Cancer is suffered from, occurs whole body fatigue and weak after chemotherapy, apathetic, cold perspiration is drowsiness, and anorexia is detested
Food, nausea and vomiting, the corners of the mouth generate bleb, the reduction of haemocyte and de- originator：Recovery from illness 69, accounts for 78%；It effective 11, accounts for
13%；Effective 5, account for 6%：Invalid 3, account for 3%.；Cause death falls off 11.
Above-mentioned clinical test proves that pharmaceutical composition of the invention has preferable effect to adjusting body immunity,
To hypoimmunity hypoimmunity especially caused by cancer stricken and cancer treatment procedure caused by enhancing a variety of causes
There is preferable adjustment effect, there is the features such as significant in efficacy, wide adaptation range.
Claims (6)
1. a kind of composition enhanced human immunity, which is characterized in that in parts by weight, by following material composition：
1-30 parts of Rosa roxburghii Tratt, 1-30 parts of emblic, 0.5-25 parts of pomegranate, 0.5-25 parts of honey, 0.1-20 parts of mangosteen, 0.1-20 parts of coconut,
0.1-20 parts of lemon, 0.1-20 parts of walnut, 0.01-10 parts of Rhizoma Gastrodiae, 0.01-10 parts of ganoderma lucidum, 0.01-10 parts of moringa seeds.
2. composition according to claim 1, which is characterized in that in parts by weight, by following material composition：Thorn
1-20 parts of pears, 1-20 parts of emblic, 0.5-20 parts of pomegranate, 0.5-20 parts of honey, 0.1-15 parts of mangosteen, 0.1-15 parts of coconut, lemon
0.1-15 parts of lemon, 0.1-15 parts of walnut, 0.1-10 parts of Rhizoma Gastrodiae, 0.1-10 parts of ganoderma lucidum, 0.1-10 parts of moringa seeds.
3. composition according to claim 1, which is characterized in that in parts by weight, by following material composition：Thorn
5-15 parts of pears, 5-15 parts of emblic, 1-15 parts of pomegranate, 1-15 parts of honey, 1-15 parts of mangosteen, 1-15 parts of coconut, 1-15 parts of lemon,
1-15 parts of walnut, 0.1-5 parts of Rhizoma Gastrodiae, 0.1-5 parts of ganoderma lucidum, 0.1-5 parts of moringa seeds.
4. according to the composition described in claim 1-3, which is characterized in that the preparation method of the Chinese medicine composition is described to take
Substance after one or more methods in crushing, decoction, alcohol extracting, immersion, diacolation, fermentation are prepared into powder, solution or clear cream,
It is prepared into oral preparation using conventional formulation means.
5. composition according to claim 4, which is characterized in that the oral preparation is tablet, granule, capsule
Agent, oral solution, syrup, pill, paste, medicinal tea etc..
6. according to the composition described in claim 1-5, in preparing the drug, health food and the food that enhance human immunity
Application.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL2030836B1 (en) * | 2022-02-07 | 2023-08-14 | Jingzhiyuan Ganoderma Lucidum Planting Cooperative In Hengshui Dev Zone | Ganoderma lucidum fermentative liquid food and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL2030836B1 (en) * | 2022-02-07 | 2023-08-14 | Jingzhiyuan Ganoderma Lucidum Planting Cooperative In Hengshui Dev Zone | Ganoderma lucidum fermentative liquid food and preparation method thereof |
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