CN108574826A - Observe device, the communications cable and photographic device - Google Patents
Observe device, the communications cable and photographic device Download PDFInfo
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- CN108574826A CN108574826A CN201810193224.7A CN201810193224A CN108574826A CN 108574826 A CN108574826 A CN 108574826A CN 201810193224 A CN201810193224 A CN 201810193224A CN 108574826 A CN108574826 A CN 108574826A
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- observation device
- image
- image pickup
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- 230000007246 mechanism Effects 0.000 claims abstract description 48
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- 238000003384 imaging method Methods 0.000 description 12
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Classifications
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N7/00—Television systems
- H04N7/18—Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
- H04N7/183—Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast for receiving images from a single remote source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
- G03B17/00—Details of cameras or camera bodies; Accessories therefor
- G03B17/55—Details of cameras or camera bodies; Accessories therefor with provision for heating or cooling, e.g. in aircraft
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/56—Cameras or camera modules comprising electronic image sensors; Control thereof provided with illuminating means
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/60—Control of cameras or camera modules
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/60—Control of cameras or camera modules
- H04N23/66—Remote control of cameras or camera parts, e.g. by remote control devices
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/60—Control of cameras or camera modules
- H04N23/69—Control of means for changing angle of the field of view, e.g. optical zoom objectives or electronic zooming
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N5/00—Details of television systems
- H04N5/76—Television signal recording
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N7/00—Television systems
- H04N7/10—Adaptations for transmission by electrical cable
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1486—Counting the particles
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Signal Processing (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Cell Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Insulated Conductors (AREA)
- Cooling Or The Like Of Electrical Apparatus (AREA)
- Communication Cables (AREA)
- Studio Devices (AREA)
Abstract
Observation device, the communications cable and photographic device are provided.Observation device has：Image pickup part, setting in the housing, image sample；1st mobile mechanism, setting in the housing, make image pickup part be moved in the 1st direction；And cooling end, it configures in the 1st mobile mechanism, the image pickup part is cooled down along the 1st direction.
Description
Technical field
The communications cable the present invention relates to observation device and for this observation device etc..
Background technology
In observation device and electronic equipment, fever caused by the high functionality and high performance by image pickup part etc. becomes
Project.Wish to inhibit as much as possible on the influential heat of observation object.
About the heat dissipation technology of this electronic equipment, for example, the computer in Japanese Unexamined Patent Application Publication 2001-524265 bulletins is used
In electric power cable heat exchanger, the power cable being connect with the computer as electronic equipment has the heat dissipation machine of fan etc.
Structure.
Invention content
The purpose of the present invention is to provide a kind of observation device that can efficiently cool down image pickup part and it is used for this observation
The communications cable, the photographic device of device etc..
1st mode according to the present invention, a kind of observation device for observing sample, the observation device have：Camera shooting
Portion, setting in the housing, image the sample；1st mobile mechanism, it is disposed in the housing, make described take the photograph
It is moved in the 1st direction in picture portion；And cooling end, it is configured at the 1st mobile mechanism, along the 1st direction to the camera shooting
Portion is cooled down.
2nd mode according to the present invention, a kind of communications cable, the communications cable have for device and being used for observation
Control the observation device the data signal line that is communicated of controller and for from the controller to the observation dress
Set the power cord for carrying out power supply, wherein the communications cable has：Heat transmitting member makes taking the photograph for from described device
As the heat that portion discharges is moved to the controller；And cooling mechanism, the heat transmitting member is cooled down.
3rd mode according to the present invention, a kind of photographic device image object, wherein the photographic device
Have：Image pickup part, setting in the housing, image the object；Cooling end carries out the image pickup part cold
But；And radiating part, by clip the image pickup part it is opposite with the cooling end in a manner of configure in the shell, receive logical
Cross the heat that the cooling end comes from image pickup part movement.
Description of the drawings
Fig. 1 is the schematic diagram of the outline of the appearance for the observing system for showing an embodiment.
Fig. 2 is the vertical view of image pickup part.
Fig. 3 is the enlarged drawing near image processing circuit.
Fig. 4 is the block diagram of the outline of the configuration example for the observing system for showing an embodiment.
Fig. 5 A are the schematic diagrames of the outline for the appearance for showing the communications cable.
Fig. 5 B are the sectional views of the communications cable.
Fig. 5 C are the schematic diagrames of the inside of radiating part.
Fig. 6 is the circuit diagram of the inside of radiating part.
Fig. 7 is the flow chart of an example for the observation device control process for showing an embodiment.
Fig. 8 is the flow chart of an example for the controller control process for showing an embodiment.
Fig. 9 A are the schematic diagrames of an example for showing the display in controller.
Fig. 9 B are the schematic diagrames of an example of display when showing the certain observation in controller.
Fig. 9 C are the schematic diagrames of an example of display when showing the temperature rise in controller.
Specific implementation mode
In the following, being illustrated to one embodiment of the present invention with reference to attached drawing.The observing system of present embodiment is to training
Cell, groups of cells, tissue etc. in supporting are imaged, the system for recording number, form of cell or groups of cells etc..As signal
Figure, Fig. 1 show the outline of the appearance of observing system 1.As shown in Figure 1, observing system 1 has observation device 100 and controller
200.As shown in Figure 1, observation device 100 is substantially writing board shape.It is used as observation object in the upper surface configuration of observation device 100
Sample.The observation device 100 for being configured with sample is for example arranged in incubator.That is, sample is observing device 100 in configuration
In the state of upper surface, such as incubator, clean bench can be passed in and out etc..It is carried out as a result, while maintaining certain environment
When observation, it is accordingly required in particular to the problem of paying attention to fever.In the present embodiment, such typical example is shown, though due to
It is not so to dislike inside incubator but that the environment of temperature variation is also very much, therefore the application range of the present invention is without being limited thereto yet.
The sample of measurement object as observing system 1 is for example as follows.Sample is for example including container, culture medium, thin
Born of the same parents and reflecting plate.Culture medium is placed in container, and cell is cultivated in culture medium.Container for example can be Pi Shi cultures
Ware (petri dish), culture bottle (flask), porous plate (Multiwell Plates) etc..As a result, for example, container is to be used for
Cultivate the culture vessel of biological sample.Shape, the size etc. of container are not limited.Culture medium can be fluid nutrient medium,
It can be solid medium.Measurement object is, for example, cell.Measurement object can be attached cell, can also be suspension cell.
In addition, cell can also be orbicule or tissue.Also, cell can derive from any biology, can also be bacterium etc..As a result,
Sample includes biology or the sample i.e. live body sample from biology.Reflecting plate is used to make to be incident on via transparent panel the photograph of sample
Mingguang City is reflected, and is illuminated to cell, is configured in the upper surface of container.This illumination may also become pyrotoxin.Especially exist
In the case of amplifying observation, the observation close to sample is more.Further, since device easy tos produce shadow, therefore illumination portion is set
The case where setting near image pickup part is more.Therefore, illumination portion and image pickup part are higher as the possibility of larger heat source altogether.
In the present embodiment, it is illustrated also by the device with such illumination portion and image pickup part, to be readily appreciated that hair
Bright content.It is of course also possible to not have illumination portion.It is shown carefully as this sample for being easy to be acted upon by temperature changes
Born of the same parents, but be also effective with the application on the way in the other samples of amplifying observation.
Continue to explain observing system 1.For the following description, in the main surface parallel with the transparent panel for observing device 100
Orthogonal X-axis and Y-axis are defined in face, and Z axis is defined in a manner of vertical with X-axis and Y-axis.
Observing device 100 has shell 101, transparent panel 102 and image acquisition unit 150.In the upper surface of shell 101
Configured with transparent panel 102.Image acquisition unit 150 is arranged in the inside of shell 101.Image acquisition unit 150 is via transparent panel
102 pairs of samples illuminate, in addition, being imaged to sample to obtain the image of sample.
Transparent panel 102 is for example formed by glass.Sample is allowed to stand on transparent panel 102.In Fig. 1, transparent panel 102 is whole
Body is transparent, but it is transparent that transparent panel 102, which can also be configured to only a part, and other parts are opaque.In addition, here, institute
It is to indicate it is transparent for the wavelength of illumination light to call transparent.
For the position of the configuration sample on unified transparent panel 102, or fixed sample, can be put on transparent panel 102
It sets and uses fixed frame.Here, for example, fixed frame is configured to have size identical with transparent panel 102 etc., relative to transparent panel
102 configurations are in specific position.For example, observation device 100 is become by including portion's material of shell 101 and transparent panel 102 in it
The state that portion is sealed.
Image acquisition unit 150 has image pickup part 151, illumination portion 155, support portion 165 and cooling fin 166.Such as Fig. 1 institutes
Show, illumination portion 155 is set to support portion 165, in addition, image pickup part 151 is arranged near illumination portion 155.Illumination portion 155 is to saturating
The direction radioluminescence light of sample is placed in direction where isotropic disk 102.In addition, image pickup part 151 takes the photograph the direction of sample
Picture obtains the image of sample.The high conductivity material as silver, copper, aluminium of cooling fin 166 is formed.Such as Fig. 2 of cooling fin 166
The shown support portion 165 for being installed on image acquisition unit 150, so as to receive from the wind as the cooling end subsequently illustrated
The wind of fan 167.Cooling fin 166 can be integrally formed with support portion 165.In the observation carried out using observation device 100, take the photograph
As the camera shooting of sample is repeated in portion 151.Therefore, image pickup part 151 generates heat.In addition, in the camera shooting of image pickup part 151, due to shining
Bright portion 155 is also irradiated the radiation of light, therefore illumination portion 155 also generates heat.Due to these image pickup parts 151 and illumination portion 155
Calorific value, the damages such as thermal shock may be caused to the cell in sample.On the other hand, since shell 101 is configured to airtight
Property, therefore the heat that image acquisition unit 150 generates is easy to be trapped in the inside of shell 101.
As a result, in the present embodiment, cooling mechanism is set in the inside of shell 101.That is, by cooling fin 166 receive Lai
From the wind of fan 167, to the fever due to image pickup part 151 and illumination portion 155 from the heat after the heat dissipation of cooling fin 166 to figure
As the direction of processing circuit 120 is moved.Such as follow-up explanation, heat dissipation is also equipped with from image processing circuit 120 to the communications cable 300
Mechanism.The heat transmitted from image acquisition unit 150 is radiated by image processing circuit 120 and the communications cable 300.As a result,
In the present embodiment, it is gas-cooled to image pickup part 151 and illumination portion 155 by fan 167, to inhibit 151 He of image pickup part
The heat of illumination portion 155.
Observing device 100 also has mobile mechanism 160.Mobile mechanism 160 has X feed screws 161 and is moved as the 1st
The X actuators 162 of motivation structure.X feed screws 161 make support portion 165 be moved in X-direction with X actuators 162.In addition, mobile
Mechanism 160 has Y feed screws 163 and the Y actuators 164 as the 2nd mobile mechanism.Y feed screws 163 and Y actuators
164 make support portion 165 be moved in Y direction.
Also, mobile mechanism 160 has fan 167.Even if fan 167 is with image acquisition unit 150 in X-direction or Y
Axis direction is mobile, also can be installed on X actuators 162 to the mode of the blowing of image acquisition unit 150, and is blown along X-direction
Wind.X actuators 162 are installed on Y feed screws 163, are driven in Y actuators 164 so that support portion 165 is moved in Y direction
It is moved in Y direction when dynamic.Therefore, fan 167 and support portion 165 are constant in the relative position of Y direction.In contrast, in X
Actuator 162 is driven so that support portion 165 is when X-direction moves, the phase of fan 167 and support portion 165 in X-direction
To position change.However, since fan 167 is in X-direction blowing, even if the X-direction of fan 167 and support portion 165
Relative position change, the wind from fan 167 can also blow to the support portion 165 of image acquisition unit 150.In addition, in Fig. 1
In, fan 167 is installed on X actuators 162, but as long as being that can continue blowing fan 167 if support portion 165 moves
X actuators 162 can be not necessarily installed on.For example, can in addition be arranged except mobile mechanism 160 for making fan 167 move
Dynamic mobile mechanism.
By changing the focal position of image pickup part 151, to change the camera position of Z-direction.That is, replacing changing camera shooting
The focal position in portion 151, mobile mechanism 160 can have for make the Z feed screws that support portion 165 is moved in Z-direction with
And Z actuators etc..
Observation device 100 makes mobile mechanism 160 change image acquisition unit 150 in the x-direction and the z-direction on one side as a result,
Position, camera shooting is repeated on one side to obtain multiple images.In addition, observation device 100 synthesizes these images to generate one
A image.Here, the image generated is, for example, to indicate the face vertical with 151 Guang Shaft of image pickup part, i.e. parallel with transparent panel 102
The image in face.Also, observation device 100 makes camera position change in a thickness direction on one side, on one side in the x-direction and the z-direction
Change position, camera shooting is repeated on one side.Also, observation device 100 synthesizes the result of camera shooting, obtains each Z successively
Image in the position of direction.Here, thickness direction refers to 151 directions Guang Shaft of image pickup part i.e. Z-direction, it is and transparent panel 102
Vertical direction.The image at three-dimensional each portion is obtained as a result,.
Here, show the example that camera shooting is repeated while in z-direction changing imaging surface, but can not also
Multiple images are obtained in z-direction, and camera shooting is repeated while only in an X direction with change of location in Y-direction.In the feelings
Under condition, the composograph of 1 plane can be obtained.It, can be in addition, the adquisitiones about the image in multiple Z-direction positions
It is the position of fixed Z-direction, is scanned in the x-direction and the z-direction, later, changes the position of Z-direction again in the side X
To be scanned in Y-direction.Furthermore, it is possible to be to change the position of Z-direction on one side in each position of X-direction and Y-direction
It is repeatedly imaged on one side, on one side carrying out the multiple camera shooting while X-direction and Y-direction are scanned.It can also apply to not
The camera shooting for the specified point being scanned.
In addition, shown in Fig. 1, observation device 100 also has circuit group 104.Circuit group 104 is arranged in the inside of shell 101,
Include multiple circuits of the control for carrying out observation device 100.In addition to circuit group 104, observation device 100 also has at image
Manage circuit 120.Image processing circuit 120 is configured in the position far as possible from image acquisition unit 150 of shell 101.In Fig. 1
Example in, the configuration of image processing circuit 120 clips image acquisition unit 150 in the inside of the shell 101 of observation device 100
Opposite position, that is, configure in the right part of shell 101 with fan 167 (X actuators 162).Also, image processing circuit 120
It is electrically connected with image acquisition unit 150 via cable 168, and is electrically connected with circuit group 104 via cable 105.
Image processing circuit 120 is with the image pickup part 151 of image acquisition unit 150 and illumination portion 155 again it is calorific value is big
Circuit.Therefore, by as the image acquisition unit 150 of heat source and 120 separate configuration of image processing circuit, to inhibit to observe
The excessive temperature rise of device 100.In addition, being provided with radiating part 121 shown in Fig. 3 in image processing circuit 120.Heat dissipation
Portion 121 is, for example, silver plate, is installed on image processing circuit 120.Radiating part 121 is by the heat transmitted from support portion 165 via figure
As processing circuit 120 is transmitted to the communications cable 300.In addition, the heat generated in image processing circuit 120 is not via radiating part
121 and to the communications cable 300 transmit.
The spacing body formed by heat-insulating material can be set between image acquisition unit 150 and image processing circuit 120.It is logical
This structure is crossed, the heat generated in image processing circuit 120 can be inhibited to be transmitted to image acquisition unit 150.
In addition, in the example of fig. 1, circuit group 104 and 120 separate configuration of image processing circuit, but circuit can also be made
Group 104 is located at the position of image processing circuit 120.
In addition, in the general photographic device of the mobile mechanism 160 without image pickup part 151, can also apply above-mentioned
The structure of air cooling.As long as that is, to clip image pickup part 151 and with as the fan 167 of cooling end it is opposite in a manner of configure radiating part
121, the heat to be shed by drying image pickup part 151 is spread, and radiating part 121 is transferred into.
Image processing circuit 120 is connect via the communications cable 300 with controller 200.In the example of fig. 1, via communication
Cable 300 and image processing circuit 120 carry out the communication between observation device 100 and controller 200.About the communications cable 300,
Subsequently illustrate.
Such as controller 200 is set in the external of incubator.200 one side of controller is filled via the communications cable 300 and observation
Set 100 actions for carrying out communication one side controlled observation device 100.Controller 200 is, for example, personal computer (PC), plate
Information terminal etc..Plate information terminal is illustrated in Fig. 1.For example, it is provided with input/output unit in controller 200,
The input/output unit has input unit as display device as liquid crystal display and touch panel.Input unit removes
Can also include switch, driver plate, keyboard, mouse etc. except touch panel.In addition, being provided with controller in controller 200
Side communication device 240.Controller side communication device 240 is the device for being communicated with observation device 100.In addition, controlling
The controller side control circuit 210 for the control into line control unit 200 is provided in device 200 processed.
Fig. 4 is the block diagram of the outline of the configuration example for the observing system for showing an embodiment.In addition, for above-mentioned knot
Structure suitably omits the description.As shown in figure 4, the image pickup part 151 of image acquisition unit 150 includes imaging optical system 152 and camera shooting
Element 153.Image pickup part 151 according to via imaging optical system 152 in the imaging surface of photographing element 153 picture of imaging and give birth to
At image data.Imaging optical system 152 is the optical system that can be focused, and is preferably able to the zoom of change focal length
Optical system.Illumination portion 155 has lamp optical system 156 and light source 157.The illumination light radiated from light source 157 is via illumination
Optical system 156 is illuminated to sample.As noted previously, as the possibility that image pickup part 151 and illumination portion 155 generate heat is high, therefore
It is cooled down by fan 167.
Observing device 100 has observation side writing circuit 130.Observation side writing circuit 130 is set to circuit group 104, example
Such as record the program that uses and various parameters in each portion of observation device 100, image acquisition unit 150 Move Mode and sweep
Retouch pattern, the data etc. that observation device 100 obtains.In addition, such as temporary recording image data of observation side writing circuit 130 (as
Prime number evidence), record with image data, display image data, action when processing data as various data.In addition, note
Record measured value for example including measurement of data obtained by observation device 100 in observation side writing circuit 130, opening of measuring
Beginning condition, acquirement image, camera position, imaging conditions, analysis result etc..
In addition, as described above, observation device 100 has image processing circuit 120.Image processing circuit 120 is to by imaging
The image data that portion 151 obtains implements various image procossings.For example, carrying out the number after image procossing by image processing circuit 120
According to being recorded in observation side writing circuit 130, or it is sent to controller 200.In addition, image processing circuit 120 can also
Carry out the various parsings based on obtained image.For example, image processing circuit 120 includes according in obtained image zooming-out sample
Cell or groups of cells image, or calculate the quantity of cell or groups of cells.Thus obtained analysis result is for example recorded in
In observation side writing circuit 130, or it is sent to controller 200.
In addition, observation device 100 has observation side communication device 140.Observation side communication device 140 is set to circuit group
104, it is the device for being communicated with controller 200.The cable modem via the communications cable 300 can be used in the communication
Letter.
In addition, observation device 100 has sensor portion 171.Sensor portion 171 includes temperature sensor.For example, sensor
Portion 171 is according to measuring control signal that control unit 116 exports into trip temperature, the measurement of humidity.In addition, for example, temperature sensor
Including multiple temperature sensors, so as to measure the inside of the shell 101 of observation device 100, especially image acquisition unit
150 and the periphery of image processing circuit 120, shell 101 and transparent panel 102 temperature.Sensor portion 171 can also have wet
Spend the sensor other than the temperature sensors such as sensor, pressure sensor.
In addition, observation device 100 also has observation side control circuit 110, clock portion 172 and power supply 190.Observation side control
The action in each portion possessed by 110 controlled observation device 100 of circuit processed.In addition, observation side control circuit 110 carries out observation device
100 various controls.As shown in figure 4, observation side control circuit 110 have as position control section 111, imaging control part 112,
Lighting control section 113, recording control part 115, measures control unit 116 and the work(in fan control portion 117 at communication control unit 114
Energy.Position control section 111 controls the action of mobile mechanism 160, the position of control image acquisition unit 150.Imaging control part 112
Control the action of image pickup part 151 possessed by image acquisition unit 150.Lighting control section 113 controls 150 institute of image acquisition unit
The action for the illumination portion 155 having.Communication control unit 114 is managed via the logical with controller 200 of observation side communication device 140
Letter.The record of data of the recording control part 115 to being obtained by observation device 100 controls.Control unit 116 is measured to surveying
The measurements such as the opportunity of amount and number are integrally controlled.Fan control portion 117 controls the action of fan 167.For example, fan control
Portion 117 starts the action of fan 167 when detecting the temperature rise of image acquisition unit 150.Also, fan control portion
117 also control the action of the cable fan for being set to the communications cable 300 subsequently illustrated.
Clock portion 172 generates time information and is exported to observation side control circuit 110.The time information is for example used for
The judgement of the action of observation device 100 when the record of acquirement data.
Power supply 190 receives the power supply from controller 200 via the communications cable 300 and is had to observation device 100
Each portion having supplies electric power.In addition, for example, power supply 190 may include the battery of lithium ion etc., external confession can also be applied in combination
Electricity and battery.
In conclusion the figure by generating image data via the camera shooting of transparent panel 102 is arranged in the inside of shell 101
As acquisition unit 150 and the mobile mechanism 160 for making image acquisition unit 150 move, so as to be designed as, reliability is high, holds
It is disposable and cleaning, and can prevent pollution etc. structure.
In addition, controller 200 has controller side writing circuit 230.For example, controller side writing circuit 230 is recorded in
The program and various parameters used in controller side control circuit 210.In addition, controller side writing circuit 230 is to passing through observation
Device 100 obtains, and the data that device 100 receives from are recorded.
Controller side control circuit 210 has as systems control division 211, display control unit 212, recording control part 213
And the function of communication control unit 214.Systems control division 211 carries out the various operations of the measurement for controlling sample.Display control
Portion 212 processed controls the action of display device 272.Display control unit 212 makes display device 272 show necessary information etc..Record
Control unit 213 is controlled to be recorded to the information of controller side writing circuit 230.Communication control unit 214 via controller side to communicating
The communication with observation device 100 of device 240 is controlled.
In addition, observation side control circuit 110, image processing circuit 120 and controller side control circuit 210 include center
Processor (CPU, Central Processing Unit), application-specific integrated circuit (ASIC, Application Specific
Integrated Circuit) or the collection such as field programmable gate array (FPGA, Field Programmable Gate Array)
At circuit etc..Observation side control circuit 110, image processing circuit 120 and controller side control circuit 210 can be respectively by one
The compositions such as a integrated circuit can also be constituted the combinations such as multiple integrated circuits.In addition, observation side control circuit 110 and figure
As processing circuit 120 can be made of integrated circuit etc..In addition, the position control section 111 of observation side control circuit 110,
Imaging control part 112, communication control unit 114, recording control part 115, measures control unit 116 and fan at lighting control section 113
Control unit 117 can be made of integrated circuit etc. respectively, can also constitute the combinations such as multiple integrated circuits.In addition,
Position control section 111, lighting control section 113, communication control unit 114, recording control part 115, measures control at imaging control part 112
2 or more control units in portion 116 and fan control portion 117 processed can be made of integrated circuit etc..Similarly, it controls
Systems control division 211, display control unit 212, recording control part 213 and the communication control unit 214 of device side processed control circuit 210
It can be made of, the combinations such as multiple integrated circuits can also be constituted integrated circuit etc. respectively.In addition, systems control division
211, more than two control units in display control unit 212, recording control part 213 and communication control unit 214 can be by one
The compositions such as a integrated circuit.For example, according in observation side writing circuit 130 or controller side writing circuit 230, integrated circuit
Posting field in the program that records carry out the actions of these integrated circuits.
Each element possessed by observation side writing circuit 130, controller side writing circuit 230 or these circuits is, for example, to dodge
Such nonvolatile memory is deposited, but there can also be static RAM (SRAM, Static Random
Access Memory) and dynamic random access memory (DRAM, Dynamic Random Access Memory) as easily
The property lost memory.In addition, each element and controller side writing circuit possessed by observation side writing circuit 130 or these circuits
230 or these circuits possessed by each element can be made of respectively memory etc., multiple memories etc. can also be combined
It constitutes.In addition it is also possible to using the database positioned at the outside of observing system 1 as a part for the memory.
Secondly, the communications cable 300 is illustrated.The image processing circuit 120 of the communications cable 300 and observation device 100
It is connected in a manner of it can dismantle.The communications cable 300 is can to carry out both data communication and power supply of USB cable etc.
Cable.Fig. 5 A are the schematic diagrames of the outline for the appearance for showing the communications cable.The communications cable 300 have connection metal parts 301,
Connector portion 302, cooling mechanism 304 and covering portion 305.Alternatively, it is also possible to cannot from image processing circuit 120 dismantle
Mode constitutes the communications cable 300.
The company for being in one end of the communications cable 300 and being set to image processing circuit 120 is arranged in connection metal parts 301
Connect the part of metal parts connection.The connection metal parts 301 receives when being connect with image processing circuit 120 from heat dissipation
The heat in portion 121.In addition, connection metal parts 301 also receives the heat generated by image processing circuit 120.
Connector portion 302 is formed by insulating materials in a manner of covering around connection metal parts 301.Connector portion
302 be the part held by user when being connect with image processing circuit 120 communications cable 300.In the connector portion 302
In be formed with heat dissipation mark 303.Mark 303 radiate by stamping in connector portion 302 or the shapes such as adhering advertisment paper (seal)
At.The heat dissipation mark 303 is the mark for making the heat dissipation direction (direction of heat flowing) in user cognition observing system 1.
For example, heat dissipation mark 303 is the mark of pointed shape, indicate that heat is flowed along the direction of the front end at tip.In the example of Fig. 5 A
In, show heat dissipation direction be from device 100 towards the direction of controller 200.
Cooling mechanism 304 is set to the midway of the communications cable 300, is cooled down to the communications cable 300.It is preferred that cooling mechanism
The position that user of 304 configurations outside incubator can see.This is to be set to cooling mechanism 304 to allow users to see
The display of indicator.About the detailed of cooling mechanism 304, subsequently illustrate.
Covering portion 305 is, for example, the covering portion of the communications cable 300 formed by vinyl chloride.Covering portion 305 prevents communication line
The signal wire etc. of the inside of cable 300 is exposed to outside.Here, in fig. 5, a part for covering portion 305 is removed.This be for
The state of the signal wire of the inside of the diagram communications cable 300.In fact, as shown in Figure 1, covering portion 305 can be formed in it is logical
Believe that cable 300 is all.
Fig. 5 B are the sectional views of the communications cable 300.As shown in Figure 5 B, the inner peripheral portion of covering portion 305 is provided with copper mesh line
Shielding case 306.Being mixed into for noise in order to prevent from the outside of the communications cable 300 and copper mesh line shielding case 306 is set.In copper
The ground wire 307 of convex is formed on cable shielding case 306.Ground wire 307 is functioned as the ground wire in the communications cable 300.
Further, since ground wire 307 is formed as convex, therefore have the effect of easy ting produce the heat dissipation of the inside of the communications cable 300.
Silver-plated aluminium foil layer 308 is formed in the inner peripheral portion of copper mesh line shielding case 306.Aluminium foil layer 308 is by communication line
The internal reflection heat of cable 300, to inhibit external release of the heat to the communications cable 300.
In addition, being provided with heat transmitting member 309 in the communications cable 300.Heat transmitting member 309 is good by thermal conductivity such as silver
The traditional thread binding or rodlike component that portion's material is constituted is thermally connected with metal parts 301 is connect.Heat transmitting member 309 will be sent to connection
The heat of metal parts 301 is sent to cooling mechanism 304.In addition, as long as heat transmitting member 309 is formed to the position of cooling mechanism 304
It sets.This is to inhibit heat to flow into controller 200.
In addition, the central part (core) in the communications cable 300 is formed with a pair of of data signal line 311 and a pair of of power cord
312.One end of these data signal lines 311 and power cord 312 connects via connection metal parts 301 and image processing circuit 120
It connects.In addition, the other end of data signal line 311 and power cord 312 is connect with controller 200.Data signal line 311 be for into
The signal wire of the communication of various data between row observation device 100 and controller 200.Power cord 312 is for from controller
The power cord that 200 pairs of observation devices 100 are powered.Observation device 100 is driven by the electric power supplied via power cord 312.
Here, the space H formed between the core and silver-plated aluminium foil layer 308 of the communications cable 300 can utilize resin layer
Deng being insulated, can also be insulated using air layer.In the case that in space, the inside of H is made of air layer, it is configured to
It can be gas-cooled to the inside of space H by the wind of the cable fan subsequently illustrated.That is, the communications cable 300 could also say that
The communications cable of control unit is transmitted with the heat that heat transmission is blocked or mitigated between observation device 100 and controller 200.
Fig. 5 C are the schematic diagrames of the inside of cooling mechanism 304.In the inside of cooling mechanism 304, do not set in the communications cable 300
It is equipped with covering portion 305, but copper mesh line shielding case 306 is exposed outside.Also, it is internally provided with cable in cooling mechanism 304
Fan 315, the part 314 for receiving the copper mesh line shielding case 306 of the wind from cable fan 315 are opened in fin-shaped, silver-plated aluminium
Layers of foil 308 is exposed.By this structure, the wind from cable fan 315 to silver-plated aluminium foil layer 308, the communications cable 300
Especially heat transmitting member 309 is gas-cooled.
Fig. 6 is the circuit diagram of cooling mechanism 304.As shown in fig. 6, cooling mechanism 304 has cable fan 315, indicator
316, switch 317, temperature sensor 318a and 318b and control circuit 319.
Cable fan 315 is connect via switch 317 with power cord Vbus (above-mentioned power cord 312).It is connected in switch 317
When, which receives the power supply from power cord Vbus and is driven.As shown in Figure 5 C, it is configured to come from cable wind
The wind of fan 315 is to aluminium foil layer 308.
Indicator 316 is, for example, LED, is connect with power cord Vbus (above-mentioned power cord 312), receives and comes from control circuit
319 signal carries out bright light.Such as online guy fan 315 driving when, 316 bright light of indicator makes user cognition to cable wind
Fan 315 is working.In addition, indicator 316 may be constructed to change bright light color according to the action state of cable fan 315.
For example, can online guy fan 315 heat dissipation effect it is insufficient equal whens, change bright light color.
Switch 317 receives the control signal of control circuit 319 to be switched on or switched off.Switch 317 is when connecting, to power cord
Vbus (above-mentioned power cord 312) is attached between cable fan 315.At this point, the driving of initial guy fan 315.Separately
On the one hand, switch 317 cuts off power cord Vbus (above-mentioned power cord 312) when disconnecting between cable fan 315.This
When, the driving of stop line guy fan 315.
The side for the observation device 100 that temperature sensor 318a is arranged in cooling mechanism 304, detects the communications cable 300
Observation device 100 side temperature.The side of the controller 200 in cooling mechanism 304 is arranged in temperature sensor 318b,
Detect the temperature of the side of the controller 200 of the communications cable 300.
Control circuit 319 is for example made of CPU, the output to the output and temperature sensor 318b of temperature sensor 318a
It is compared, judges the temperature gradient (temperature difference) of the communications cable 300.Also, control circuit 319 controls switch 317
So that the temperature gradient of the communications cable 300 becomes smaller, to drive cable fan 315.In addition, control circuit 319 and data signal line D
+ and D- (above-mentioned data signal line 311) connections.When receiving the fan control signal from controller 200, control circuit
319 control switches 317 to drive cable fan 315.Have in observation device 100 and controller that is, the communications cable 300 becomes
The communications cable that the heat that heat is transmitted transmits control unit is mitigated between 200.
Then, the action of observing system 1 is illustrated.Fig. 7 be show to be communicated between controller 200 institute into
The flow chart of an example of capable observation device control process.When the power supply for observing device 100 is connected, start the observation dress of Fig. 7
Set control process.Observe device 100 power supply connect the case where have such as user to power switch possessed by power supply 190 into
Gone operation the case where, with the connected situation of external power supply, become it is set at the time of the case where etc..In addition, for example, can be with
It is depending on the user's operation, in the case where receiving the control signal powered on from controller 200, to power on.
In step S101, observation side control circuit 110 is standby until receiving the device 100 with from from controller 200
Act, various settings etc. are until relevant control signal.When receiving control signal, observation side control circuit 110 differentiates
The content of the control signal received.
In step s 102, observation side control circuit 110 is made whether that receiving instruction from controller 200 executes specific sight
The judgement for the control signal examined.Certain observation is the observation and measurement that user specifies some specific position to carry out.For example, for
Think the region of observation, user specifies on one side watching while live view is shown and operation and control device 200, or to controller 200
Input indicates that the position coordinates in the region are specified.Indicate that it for example includes for making image to execute the control signal of certain observation
The operation movable signal or coordinate signal that acquisition unit 150 is moved to the position for carrying out certain observation.The operation movable signal is
The signal for the result that controller 200 is grasped is directed at while watching live view and showing based on user.The coordinate signal is base
In the signal of the position coordinates input by user for indicating the region.It is being judged to receiving the control letter of instruction execution certain observation
In the case of number, observation device control process enters step S103, in the control for being determined as that no indication is received and executing certain observation
In the case of signal processed, S105 is entered step.
In step s 103, observation side control circuit 110 is according to the operation based on user received from controller 200
Movable signal or coordinate signal are operated, 160 mobile image acquisition unit 150 of mobile mechanism is made.In addition, observation side control circuit
110 make the position of image acquisition unit 150 after movement be imaged, and observation side communication device 140 is made to be sent to controller 200
Acquired image.
In step S104, observation side control circuit 110 is made whether to terminate the judgement of certain observation.It is judged to terminating special
Surely the case where observing is, for example, the feelings that the control signal that instruction corresponding with the operation of user terminates is received from controller 200
Condition.In the case where being judged to terminating certain observation, observation device control process enters step S105, be not judged to terminating spy
In the case of fixed observation, return to step S103.
In step S105, observation side control circuit 110 is made whether that receiving instruction from controller 200 executes counting place
The control signal of reason.In the case where being determined as that receiving instruction executes the control signal for counting processing, observe at device control
Reason enters step S106, in the case where not being determined as that receiving instruction executes the control signal for counting processing, enters step
S113。
In step s 106, observation side control circuit 110 executes counting processing.In counting processing, for example, observation side control
Circuit 110 processed makes 160 mobile image of mobile mechanism obtain single according to the Move Mode recorded in observation side writing circuit 130
Member 150.In addition, image acquisition unit 150 exists while moving, camera shooting is repeated to obtain image in each specified position.It sees
It examines side control circuit 110 and records acquired image etc. to observation side writing circuit 130.Also, observation side control circuit 110
Image processing circuit 120 is such as set to parse the image that image acquisition unit obtains.Observation side control circuit 110 is for example according to image
It is being parsed as a result, the number to cell counts, or to the state of cell (for example, whether cell weaker, cell whether
Live) it is evaluated, or the state of the culture medium including the color of culture medium is evaluated, to evaluate whether being to need
Replace the state of culture medium.When being judged to needing replacing culture medium by the evaluation result, the meaning is transmitted to controller 200
Purport.At this point, carrying out the warning for promoting to replace culture medium in the display device 272 of controller 200.
In addition, observation side control circuit 110 can make according to the scan pattern recorded in observation side writing circuit 130
160 mobile image acquisition unit 150 of mobile mechanism, and imaged in each specified position, carry out the entirety to sample or one
The scan process that part is scanned.For example, if implementing scan process, observation side control circuit before counting processing
110 according to image acquisition unit 150 obtain image parsed as a result, determine container position, or grasp container in
Cell distribution, come limit carry out count processing region, can shorten processing needed for time.In addition, user can lead to
Over-scan the execution of processing and the simply state of determining sample.
In addition, observation side control circuit 110 makes observation side communication device 140 send the image to controller 200.In addition,
The image obtained by scan process can be parsed to judge the state of culture medium.In addition, counting at processing and scanning
Reason for example can also be used as measurement processing and integrally carry out.
In step s 107, observation side control circuit 110 is made whether the judgement for terminating to count processing.For example, terminating
According to regulation Move Mode or scan pattern it is mobile when, handle or scanning in the counting for finishing preset number
When processing, from controller 200 receive terminate count processing the meaning control signal corresponding user's operation when etc., sentence
It is set to counting processing to terminate.In the case where being judged to terminating counting processing, observation device control process enters step S112,
It is not determined as in the case of terminating counting processing, enters step S108.
In step S108, observation side control circuit 110 judges the inside for the shell 101 that sensor portion 171 detects
Whether the temperature of temperature, particularly image acquisition unit 150 rises specified value or more.For example, the specified value is to cell
Influence the specified value of the temperature rise for the degree for allowing people to worry.It is being determined as the temperature rise of image acquisition unit 150 regulation
In the case that value is above, observation device control process enters step S109, the temperature for being determined as image acquisition unit 150 not on
In the case of having risen specified value or more, return to step S106.
In step S109, observation side control circuit 110 interrupts counting processing.That is, observation side control circuit 110 makes by moving
The mobile stopping for the image acquisition unit 150 that motivation structure 160 carries out.In addition, observation side control circuit 110 makes image acquisition unit
150 camera shooting stops.Later, observation side control circuit 110 makes observation side communication device 140 be sent to controller 200 by sensing
The temperature that device portion 171 detects.
In step s 110, observation side control circuit 110 is made whether to receive the control signal of instruction fan driving
Judgement.In the case where being judged to receiving the control signal of instruction fan driving, observation device control process enters step
S111 enters step S113 in the case of the control signal for the fan driving that is determined as that no indication is received.
In step S111,110 driving fan 167 of observation side control circuit.As noted previously, as fan 167 and image
Acquisition unit 150 comes from fan in the location matches of Y direction so no matter image acquisition unit 150 stops in which position
167 wind can blow to image acquisition unit 150.After the driving of fan 167, observation device control process enters step
S113。
In step S112, observation side control circuit 110 makes observation side communication device 140 send counting to controller 200
The result of processing.
In step S113, observation side control circuit 110 is for example according to user's operation as a result, be made whether to terminate observation
The judgement of device control process.In this step, the case where being judged to not terminating, which has for example again indicated that including user, executes spy
Fixed observation counts the case where handling.Furthermore, it is possible to which observing each portion possessed by device 100 by power switch etc. obtains user
Operation as a result, can also from controller 200 via communication obtain user's operation result.It is being judged to not terminating to observe device
In the case of control process, device control process return to step S101 is observed, in the case where being determined as end, terminates observation dress
Set control process.
Fig. 8 is the flow chart of an example for the controller control process for showing to be carried out by controller 200.For example, observing
After the power supply of device 100 is connected, start to handle shown in the flow chart of Fig. 8.
In step s 201, controller side control circuit 210 makes display device 272 possessed by input/output unit 270
The icon set (basic icon) of device 100 is for example observed in display for user's operation.Fig. 9 A show the display in controller 200
An example is as schematic diagram.For example, shown in Fig. 9 A, controller 200 make the display device 272 display include confirming operation icon I10,
Certain observation icon I11, the display information for counting icon I12 and other icon I13, wherein confirming operation icon I10 is used for
Instruction executes confirming operation, and certain observation icon I11 is used to indicate execution certain observation, counts icon I12 and is used to indicate execution
The counting processing of cell count etc. is carried out, other icon I13, which are used to indicate, executes other functions or the various settings of execution.In addition,
Controller side control circuit 210 for example based on input unit 274 result and the operation signal that exports depending on the user's operation, carries out
Whether user has selected the judgement (operation judgement) of icon.In the case where being determined as that user has selected icon, controller control
Processing enters step S202.
In step S202, controller side control circuit 210 determines whether to execute observation device control.In this step,
For example, when having selected certain observation icon I11 or having counted icon I12, it is judged to executing observation device control.It is being judged to holding
In the case of row observation device control, controller control process enters step S203.It is not judged to executing observation device control
In the case of, carry out the control other than observation device control.That is, in the case where having selected confirming operation icon I10, controller
Side control circuit 210 carries out the control of the confirming operation for carrying out observation device 100.In addition, having selected other icon I13
In the case of, controller side control circuit 210 carries out other controls.About the detailed content of confirming operation and other controls, save
Slightly illustrate.
In step S203, controller side control circuit 210 is made whether to have selected the judgement of certain observation icon I11.
In the case where being judged to having selected certain observation icon I11, controller control process enters step S204, be determined as it is unselected
That selects asks under condition, enters step S205.
In step S204, controller side control circuit 210 makes observation side communication device 140 send instruction certain observation
The control signal of beginning.Later, controller side control circuit 210 generates the display information for carrying out certain observation, and makes to show
Showing device 272 is shown.An example of display when Fig. 9 B show the certain observation in controller 200 is as schematic diagram.Such as figure
Shown in 9B, the display information that when certain observation shows in display device 272 for example includes for making mobile mechanism 160 move
Icon (moving icon) I29 is (by Y+ moving icon I25, X+ moving icon I26, Y- moving icon I27, X- moving icons I28
It constitutes).In addition, the display information further includes for carrying out the icon of focal adjustments (focal adjustments icon) I24.For carrying out coke
The icon I24 that point is adjusted for example includes icon I22 for making lens be driven to unlimited distal side and for being driven to recent side
Icon I23.Also, the display information includes being used to indicate icon (return icon) I21 for returning to front picture.
In addition, in step S204, the device 100 from of controller side control circuit 210 is obtained by image acquisition unit
150 imaged and the image that obtains, and be shown to display device 272.As shown in Figure 9 B, display information when certain observation is also
Including controller 200 from device 100 obtain, imaged by image acquisition unit 150 obtained from image P0.At this
Under state, such as user's operation moving icon I29 makes the image acquisition unit 150 be moved to desired observation position, in addition,
After movement, the observation position of Z-direction is adjusted using focal adjustments icon I24, can observe the situation etc. of cell.In addition, with
The image P0 for being obtained by image acquisition unit 150 and being shown by live view is for example watched at family on one side, carries out observation position on one side
Deng operation.The operation is carried out every time, and controller side control circuit 210 all makes observation side communication device 140 send about specific
The control signal of observation.In addition, the display information shown in certain observation may include being used to indicate the arbitrary observation of record
The camera icon of image at position can also include the current image acquisition unit 150 of expression in which position to sample
The location information imaged.
In step S205, controller side control circuit 210 is made whether the judgement for having selected to count icon I12.Sentencing
It is set in the case of having selected counting icon I12, controller control process enters step S206, is being determined as non-selected situation
Under, return to step S209.
In step S206, controller side control circuit 210 executes the control for counting processing to the observation output instruction of device 100
Signal processed.
In step S207, controller side control circuit 210 determines whether to terminate counting processing.In this step, judge
To terminate the case where Move Mode that the case where counting processing is counting or observation finishes etc..The case where being judged to terminating
Under, controller side control circuit 210 makes observation side communication device 140 send the control signal for making counting processing terminate.Later, it controls
Device control process processed enters step S209.In the case where not being determined as end, controller control process enters step S208.
In step S208, controller side control circuit 210 obtains what the image acquisition unit 150 in counting processing was shot
Image simultaneously makes display device 272 be shown.In addition, the display of the acquirement image carried out herein can be shown as live view
Come carry out.In addition, in step S208, the device 100 from of controller side control circuit 210 obtains image, counts processing
As a result it waits and is shown to display device 272.In addition, being made whether to need replacing the judgement of culture medium etc., display police as needed
It accuses.In addition, for whether needing replacing the judgement of culture medium etc., can be carried out by observation device 100, it can also be by controller
200 carry out.Later, controller control process return to step S206.
In step S209, controller side control circuit 210 determines whether to carry out fan control.For example, being filled from
When setting the information that 100 have sent temperature, controller side control circuit 210 is generated for alerting the temperature in the presence of observation device 100
The display information risen is spent, and display device 272 is made to be shown.Fig. 9 C show that there are the temperature rises in controller 200
Warning display an example as schematic diagram.As shown in Figure 9 C, the display information example shown in display device 272 when warning
Such as include indicating that there are the message I32 of temperature rise.In addition, the display information includes the icon (wind for carrying out fan control
Fan control icon) I33.Also, the display information includes being used to indicate icon (return icon) I31 for returning to front picture.With
Family viewing message I32 judges the necessity of fan control.Also, when needing to carry out fan control, user selects fan control
Icon I33.By the selection, it is judged to carrying out fan control.In the case where being judged to carrying out fan control, controller control
Processing enters step S210, in the case where being determined as without fan control, enters step S212.In addition, in step S209
In, it is configured to when there are defined temperature rise, the not confirmation of user is also judged to carrying out fan control.For this
Kind fan control, can manually be carried out by user, can also be carried out automatically, but be related to many sides with the relevant factor of temperature rise
Face, due to for temperature tolerance and effect change also according to sample, it is possible to pair with illumination brightness,
The relevant parameter of type, use environment of sample is parsed, and more advanced judgement is carried out by artificial intelligence.
In step S210, controller side control circuit 210 makes observation side communication device 140 send for carrying out fan control
The control signal of system.In addition, in step S211, controller side control circuit 210 makes the transmission of observation side communication device 140 be used for
Carry out the control signal of cable fan control.Control signal for carrying out fan control is believed via the data of the communications cable 300
Number line 311 is input into observation device 100.The signal is received, the observation side control circuit 110 of observation device 100 drives wind
Fan 167.In addition, the control signal for carrying out cable fan control is entered via the data signal line 311 of the communications cable 300
To the control circuit 319 of cooling mechanism 304.The signal is received, control circuit 319 controls switch 317 to drive cable fan
315.Later, controller control process enters step S212.In addition, even if the not no control signal from controller 200, control
Circuit 319 drives cable fan 315 also according to the temperature gradient detected by temperature sensor 318a and 318b.
In step S212, controller side control circuit 210 determines whether to terminate observation device control.In this step,
Such as select return icon I31's the case where having selected return icon I21 during certain observation is handled or in counting processing
In the case of, it is judged to terminating observation device control.In the case where being judged to terminating observation device control, controller control process
Return to step S201.In the case where not being judged to terminating observation device control, controller control process return to step S202.
In present embodiment described above, in order to can move in the inside of the shell 101 of air-tightness is arranged
Image acquisition unit 150 be gas-cooled, configured in the X actuators 162 that X-direction moves making image acquisition unit 150
There is the fan 167 dried in X-direction.As a result, due to the relative position of image acquisition unit 150 and the Y direction of fan 167
It is constant, therefore regardless of the position of image acquisition unit 150, it can be from fan 167 by wind to image acquisition unit
150.It is efficiently gas-cooled to image acquisition unit 150 as a result,.
In addition, in a manner of clipping image acquisition unit 150 on the blowing direction in fan 167 and be opposite with fan 167
Radiating part 121 is set, so as to receive the heat from image acquisition unit 150 transmitted by fan 167.In this way
Structure can discharge the heat received by radiating part 121 via the communications cable 300 to the external of observation device 100.
Also, cooling mechanism 304 is provided in the communications cable 300, which has for in communication line
The cable fan 315 that the heat moved in cable 300 radiates.By the cable fan 315, promote to come from the communications cable 300
Heat dissipation.In addition, the communications cable 300 includes the data-signal for being communicated with the controller 200 of observation device 100
Line 311.Also use the data signal line 311 as the data signal line of the control signal for controlling cable fan 315, thus
The quantity of data signal line can be cut down.In addition, the communications cable 300 includes for carrying out power supply to observation device 100
Power cord 312.Also power supply of the power cord 312 as supply for driving the electric power of cable fan 315 and indicator 316 is used
Line, so as to supply the electric power for driving cable fan 315 and indicator 316 from controller 200.
Here, in the above-described embodiment, observation device 100 passes through having via the communications cable 300 with controller 200
Line is communicated.However, observation device 100 can also be communicated by radio communication with controller 200.
In addition, in the above-described embodiment, the warning that temperature rise is carried out in controller 200 shows sector-style fan control of going forward side by side
System is after observation device 100 has interrupted counting.In contrast, can also be configured to not interrupt the meter in observation device 100
It counts and carries out fan control.In such a case it is possible to carry out the police of temperature rise in the step S208 of controller control process
It accuses.
In addition, the communications cable 300 shown in present embodiment may be used as what the needs other than observation device 100 radiated
The communications cable of various equipment.
In addition, in the present embodiment, fan 167 is installed on X actuators 162, and is configured to dry in X-direction,
It is configured to image acquisition unit 150 integrally to move in Y direction by Y actuators 164 with fan 167.In contrast, fan
167 are installed on Y actuators 164, and are configured to dry in Y direction, and it is logical with fan 167 to be configured to image acquisition unit 150
X actuators 162 are crossed integrally to move in X-direction.
In addition, in the present embodiment, the cooling end for cooling down image acquisition unit 150 is fan.In contrast, cold
But portion can also be configured to cool down image acquisition unit 150 by water cooling.
In addition, in the present embodiment, the cooling of image acquisition unit 150 etc. is illustrated, but can also pass through
Fan 167 and cable fan 315 are changed to heater, to be heated to image acquisition unit 150 etc..
The present invention is not limited to the above embodiments, can carry out in the range of the purport of the present invention certainly various modifications and
Using.As for the part illustrated with simple branch by flow chart etc., digitization is carried out to more factors and is judged
Such improvement can be changed using point of penetration and the project of concern, therefore also become the protection model of the present invention certainly
It encloses.
Claims (9)
1. a kind of observation device for observing sample, wherein the observation device has：
Image pickup part, setting in the housing, image the sample；
1st mobile mechanism, it is disposed in the housing, so that the image pickup part is moved on the 1st direction；And
Cooling end is configured at the 1st mobile mechanism, is cooled down to the image pickup part along the 1st direction.
2. observation device according to claim 1, wherein
The observation device also has the 2nd mobile mechanism, and the 2nd mobile mechanism is installed on the 1st mobile mechanism, and described
1st mobile mechanism makes the image pickup part be moved on 2nd direction different from the 1st direction together.
3. observation device according to claim 1, wherein
Also there is the observation device radiating part, the radiating part to be configured to clip the camera shooting along the 1st direction
Portion is opposite with the cooling end, receive by the cooling end from the image pickup part move come heat.
4. observation device according to claim 3, wherein
The observation device also has an image processing circuit, described image processing circuit be configured to along the 1st direction and
The image data that the image pickup part is opposite with the cooling end, and processing is obtained by the image pickup part is clipped,
The radiating part is installed on described image processing circuit.
5. observation device according to claim 4, wherein
Also there is the observation device communications cable, the communications cable to be connect with described image processing circuit, have for passing through
The data communicated with the observation device and for controlling the controller of the observation device by described image processing circuit
Signal wire and power cord for carrying out power supply to device from described from the controller, also, the communication line
Cable has the heat transmitting member for making the heat that device discharges from described be moved to the controller and to the heat transmitting member
Carry out cooling cooling mechanism.
6. a kind of communications cable, the communications cable has for the control with observation device and for controlling the observation device
Data signal line that device is communicated and power supply for carrying out power supply to device from described from the controller
Line, wherein the communications cable has：
Heat transmitting member makes the heat that the image pickup part of the device from described discharges be moved to the controller；And
Cooling mechanism cools down the heat transmitting member.
7. the communications cable according to claim 6, wherein
The cooling mechanism is connect with the data signal line and the power cord, according to the control of the controller to the heat
Transfer part is cooled down.
8. the communications cable according to claim 6, wherein
The communications cable, which also has, transmits control unit, and the transmission control unit is between the observation device and the controller
Heat is mitigated to transmit.
9. a kind of photographic device, images object, wherein the photographic device has：
Image pickup part, setting in the housing, image the object；
Cooling end cools down the image pickup part；And
Radiating part, by clip the image pickup part it is opposite with the cooling end in a manner of configure in the shell, receive to pass through
The heat that the cooling end comes from image pickup part movement.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017-045852 | 2017-03-10 | ||
| JP2017045852A JP2018148811A (en) | 2017-03-10 | 2017-03-10 | Observation device and communication cable |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108574826A true CN108574826A (en) | 2018-09-25 |
Family
ID=63445725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810193224.7A Pending CN108574826A (en) | 2017-03-10 | 2018-03-09 | Observe device, the communications cable and photographic device |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20180262721A1 (en) |
| JP (1) | JP2018148811A (en) |
| CN (1) | CN108574826A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200146189A1 (en) * | 2018-11-06 | 2020-05-07 | Dell Products L.P. | Systems and methods for cooling with variable-location air mover |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102712890A (en) * | 2010-01-20 | 2012-10-03 | 株式会社尼康 | Cell observation device and cell culture method |
| US20160242635A1 (en) * | 2013-11-26 | 2016-08-25 | Sharp Kabushiki Kaisha | In-vivo monitoring camera system, and support tube for in-vivo monitoring camera system |
| US20160254623A1 (en) * | 2013-10-04 | 2016-09-01 | Philips Lighting Holding B.V. | Lighting device connector comprising a heat sink |
-
2017
- 2017-03-10 JP JP2017045852A patent/JP2018148811A/en active Pending
-
2018
- 2018-03-07 US US15/914,403 patent/US20180262721A1/en not_active Abandoned
- 2018-03-09 CN CN201810193224.7A patent/CN108574826A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102712890A (en) * | 2010-01-20 | 2012-10-03 | 株式会社尼康 | Cell observation device and cell culture method |
| US20160254623A1 (en) * | 2013-10-04 | 2016-09-01 | Philips Lighting Holding B.V. | Lighting device connector comprising a heat sink |
| US20160242635A1 (en) * | 2013-11-26 | 2016-08-25 | Sharp Kabushiki Kaisha | In-vivo monitoring camera system, and support tube for in-vivo monitoring camera system |
Also Published As
| Publication number | Publication date |
|---|---|
| US20180262721A1 (en) | 2018-09-13 |
| JP2018148811A (en) | 2018-09-27 |
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