CN108552320A - A kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health - Google Patents
A kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health Download PDFInfo
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- CN108552320A CN108552320A CN201810050062.1A CN201810050062A CN108552320A CN 108552320 A CN108552320 A CN 108552320A CN 201810050062 A CN201810050062 A CN 201810050062A CN 108552320 A CN108552320 A CN 108552320A
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- milk powder
- chitosan oligosaccharide
- oligosaccharide
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- aged
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/16—Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1528—Fatty acids; Mono- or diglycerides; Petroleum jelly; Paraffine; Phospholipids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/156—Flavoured milk preparations ; Addition of fruits, vegetables, sugars, sugar alcohols or sweeteners
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to milk powder fields, and in particular to a kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health, including following each component：Milk powder, chitosan oligosaccharide, xylo-oligosaccharide, dietary fiber and unsaturated fatty acid；The mass content of each component is 98~99.5 parts of milk powder, 0.15~0.25 part of chitosan oligosaccharide, 0.1~0.2 part of xylo-oligosaccharide, 0.05~0.15 part of dietary fiber, 0.05~0.15 part of unsaturated fatty acid.Present component is simple; chitosan oligosaccharide, xylo-oligosaccharide, dietary fiber and unsaturated fatty acid are added in milk powder; and define dosage; have the function of lowering blood pressure, protection angiocarpy, prevention of arterial atherosis to the middle-aged and the old; have simultaneously and inhibits Apoptosis, delays body aging, the effect for improving body immunity, enhancing resistance of human body.The present invention has market value with potential.
Description
Technical field
The present invention relates to milk powder fields, and in particular to a kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health.
Background technology
Cardiovascular disease is the disease of heart and blood vessel, also known as circulation system disease, is the high morbidity of the middle-aged and the old, mainly with
Unsound diet, shortage movement are related with heredity.The middle-aged and the old in daily life, will use less salt low first on diet
Fat, crude fibre food eat vegetable and fruit, plain boiled pork more, eat the high food of cholesterol, such as the internal organ etc. of animal less as possible.Secondly
It is reasonably moved and holding is in a cheerful frame of mind.
Chitosan oligosaccharide refers to 2~10 aminoglucose sugar with chitosan oligomer made of β-Isosorbide-5-Nitrae glucosides key connection, is gathered by shell
Sugar is degraded.Chitosan oligosaccharide is as the unique existing natural alkaline polysaccharide of nature, and bioactivity is high, nontoxic, without side-effects, easily
Biodegradation can quickly be absorbed by human body, in the fields extensive use such as medicine, functional food, daily use chemicals, agricultural.With chitosan oligosaccharide
It is capable of the immunity of body for the health food of main material production, it is anti-oxidant antitumor, promote intestinal bifidobacteria etc. beneficial
The hyperplasia of bacterium, and inhibit the growth for having toadstool.The edible food containing chitosan oligosaccharide, having to human body reduces cholesterol, improves body
Immunity inhibits diabetes, ensures the effects that cardiovascular health.Milk powder for middle-aged and old people is improved using compositions such as chitosan oligosaccharides,
Milk powder that is developing suitable the elderly's mouthfeel and nutrition while preventing and treating cardiovascular disease is for ensureing the middle-aged and the old
Cardiovascular health have great importance.
Invention content
The technical problem to be solved by the present invention is to how to overcome the shortcomings of the prior art, one kind is provided beneficial to person in middle and old age
The chitosan oligosaccharide milk powder of popular feeling vascular health.
Technical solution of the invention is：A kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health, including with
Lower each component：Milk powder, chitosan oligosaccharide, xylo-oligosaccharide, dietary fiber and unsaturated fatty acid.
Further, the parts by weight of each component are：98~99.5 parts of milk powder, 0.15~0.25 part of chitosan oligosaccharide, oligomeric wood
0.1~0.2 part of sugar, 0.05~0.15 part of dietary fiber, 0.05~0.15 part of unsaturated fatty acid.
Further, the parts by weight of each component are：99.45 parts of milk powder, 0.2 part of chitosan oligosaccharide, 0.15 part of xylo-oligosaccharide, meals
Eat 0.1 part of fiber, 0.1 part of unsaturated fatty acid.
Further, the chitosan oligosaccharide, xylo-oligosaccharide, unsaturated fatty acid purity be 95% or more.
Further, the unsaturated fatty acid is eicosapentaenoic acid.
Further, the milk powder is the composition of skimmed milk power or skimmed milk power and whole milk powder.
The method of the present invention chitosan oligosaccharide has nontoxic, Yi Sheng as the unique existing positively charged native compound of nature
The characteristic of object degradation.Chitosan oligosaccharide has fabulous water solubility, greatly expands its application range, and chitosan oligosaccharide has reducing blood lipid blood
Pressure, protects the function of cardiovascular health, also has effects that prevent senile dementia and inhibits diabetes；Chitosan oligosaccharide also has very
Good anti-oxidation function, can inhibit Apoptosis to delay body aging；Inhibit harmful intestinal tract bacteria, promotes the beneficial bacteriums such as lactic acid bacteria
Breeding；Chitosan oligosaccharide can promote the activity of osteoblast to increase by certain mechanism, promote repair of fractured bones, Saving cortilage health；
Chitosan oligosaccharide can improve the immunocompetence of body, strengthening body resistance.Xylo-oligosaccharide is also known as wood oligose, and calcium, iron can be promoted by having
It absorbs and inhibits the functions such as pathogen and diarrhea, protection liver.Dietary fiber plays important on keeping digestive system health
Role, wall of digestive can be cleaned with prevention of cardiovascular disease, cancer, diabetes and Other diseases by absorbing enough fibers
With enhancing digestive function, while the removal of the carcinogen and noxious material in food can be diluted and be accelerated, protect fragile disappear
Change and road and prevent colon cancer, and digestion rate and most rapid drainage cholesterol can be slowed down, can allow blood glucose and cholesterol in blood
Control is in optimal level.Eicosapentaenoic acid (EPA) has reduction blood fat and triglycerides, prevention of arterial atherosis
Effect, meanwhile, the antioxidation of chitosan oligosaccharide can remove free radical in the present invention, prevent EPA from being aoxidized, and EPA is made to play more
Good effect, reaches optimum efficiency.These functional raw materials are added in milk powder, person in middle and old age can be largely prevented and treated
The angiocardiopathy of people.The present invention is worth with market potential.
Specific implementation mode
With reference to embodiments, a kind of the present invention will be described in detail chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health.
Embodiment 1
A kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health includes each component of following parts by weight：Milk
98 parts of powder, 0.15 part of chitosan oligosaccharide, 0.1 part of xylo-oligosaccharide, 0.05 part of dietary fiber, 0.05 part of unsaturated fatty acid.The shell is few
Sugar, xylo-oligosaccharide, unsaturated fatty acid purity be 95% or more, the unsaturated fatty acid be eicosapentaenoic acid, it is described
Milk powder is the composition of skimmed milk power or skimmed milk power and whole milk powder.The above components are uniformly mixed, then according to existing
Technique carries out filling.
Embodiment 2
A kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health includes each component of following parts by weight：Milk
99.5 parts of powder, 0.25 part of chitosan oligosaccharide, 0.2 part of xylo-oligosaccharide, 0.15 part of dietary fiber, 0.15 part of unsaturated fatty acid.The shell
Oligosaccharides, xylo-oligosaccharide, unsaturated fatty acid purity be 95% or more, the unsaturated fatty acid be eicosapentaenoic acid, institute
State the composition that milk powder is skimmed milk power or skimmed milk power and whole milk powder.The above components are uniformly mixed, then according to existing
There is technique to carry out filling.
Embodiment 3
A kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health includes each component of following parts by weight：Milk
99.45 parts of powder, 0.2 part of chitosan oligosaccharide, 0.15 part of xylo-oligosaccharide, 0.1 part of dietary fiber, 0.1 part of unsaturated fatty acid.The shell is few
Sugar, xylo-oligosaccharide, unsaturated fatty acid purity be 95% or more, the unsaturated fatty acid be eicosapentaenoic acid, it is described
Milk powder is the composition of skimmed milk power or skimmed milk power and whole milk powder.The above components are uniformly mixed, then according to existing
Technique carries out filling.
Clinical application is tested
(1) efficiency assay
According to itself, contrast method, the volunteer to being applicable in this formula milk are divided into seminar and control group between group
Two groups, 3 chitosan oligosaccharide milk powder 30d of embodiment takes in seminar, and control group takes ordinary powdered milk 30d, measures subject again on an empty stomach
Blood glucose and 2h-plasma glucose.It lives with reference to original by gender, age, labor intensity, ideal body weight to every subject before test-meal
Custom provides corresponding diet, separately twice daily feeds milk powder, each 40g.Experimental result such as table 1.
1 seminar of table and control group validity contrast table
(2) fasting blood-glucose improves situation
Reduced parameter：Fasting blood glucose level and percentage is reduced, itself compares that there were significant differences before and after fasting blood-glucose experiment,
And average blood sugar declines >=10% after testing, there were significant differences for blood glucose value or blood glucose decline percentage compared with the control group, can sentence
It is positive to determine given the test agent fasting blood-glucose index result.
Seminar is divided into three groups, every group of 45 people take 1,2,3 milk powder of embodiment respectively, and 45 people of control group takes common
Milk powder is provided accordingly every subject by gender, age, labor intensity, ideal body weight before test-meal with reference to original living habit
Diet, separately twice daily feed milk powder, each 40g.Fasting blood-glucose comparison, experimental result such as table 2 are carried out after taking 30d.
2 fasting blood-glucose comparative situation table of table
| Group | Before test-meal (mmol/L) | After test-meal (mmol/L) | P | Difference | Rate of descent/% |
| Embodiment 1 | 9.79±0.93 | 8.53±0.70 | 0 | 1.26±0.35 | 12.87±2.77 |
| Embodiment 2 | 9.78±0.95 | 8.45±0.60 | 0 | 1.33±0.30 | 13.59±3.05 |
| Embodiment 3 | 9.79±0.91 | 8.44±0.80 | 0 | 1.35±0.28 | 13.78±2.56 |
| Control group | 9.78±0.96 | 9.46±0.92 | 0.6579 | 0.25±0.48 | 2.41±4.73 |
| P1 | 0.6846 | 0 | - | - | - |
| P2 | 0.6758 | 0 | - | - | - |
The main clinic symptoms of three groups of seminar, which improve, as can be seen from the test results is significantly better than control group.Seminar three
Group fasting blood sugar has pole significant difference (P<0.01)；Control group fasting blood sugar is without significant difference (P>0.05)；It is ground after experiment
Study carefully three groups of fasting blood-glucoses of group to decline obviously, has pole significant difference (P with control group<0.01).
(3) 2h-plasma glucose improves situation
Reduced parameter：2h-plasma glucose is horizontal and reduces percentage, itself relatively has significantly before and after 2h-plasma glucose experiment
Difference, and average blood sugar declines >=10% after experiment, there were significant differences for blood glucose value or blood glucose decline percentage compared with the control group,
It can determine that given the test agent 2h-plasma glucose index result is positive.
Seminar is divided into three groups, every group of 45 people take 1,2,3 milk powder of embodiment respectively, and 45 people of control group takes common
Milk powder is provided accordingly every subject by gender, age, labor intensity, ideal body weight before test-meal with reference to original living habit
Diet, separately twice daily feed milk powder, each 40g.2h-plasma glucose comparison, experimental result such as table 3 are carried out after taking 30d.
3 2h-plasma glucose comparative situation table of table
| Group | Before test-meal | After test-meal | P | Difference | Rate of descent/% |
| Embodiment 1 | 13.37±1.28 | 11.89±1.15 | 0 | 1.48±0.38 | 11.07±2.68 |
| Embodiment 2 | 13.38±1.30 | 11.31±1.13 | 0 | 2.06±0.42 | 15.39±3.05 |
| Embodiment 3 | 13.35±1.25 | 11.40±1.11 | 0 | 1.95±0.52 | 14.59±3.43 |
| Control group | 13.40±1.40 | 13.10±1.24 | 0.3962 | 0.31±0.84 | 2.01±6.09 |
| P1 | 0.8523 | 0 | - | - | - |
| P2 | 0.8639 | 0 | - | - | - |
| P3 | 0.8448 | 0 | - | - | - |
The main clinic symptoms of three groups of seminar, which improve, as can be seen from the test results is significantly better than control group.Seminar three
Group 2h-plasma glucose value has pole significant difference (P<0.01)；Control group 2h-plasma glucose value is without significant difference (P>0.05).Experiment
Three groups of 2h-plasma glucoses of seminar are decreased obviously afterwards, have pole significant difference (P with control group<0.01).
Any one of 2 fasting blood-glucose, the 2h-plasma glucose indexs positive can determine that the given the test agent has hypoglycemic work(
Energy.Therefore the milk powder for continuously taking the present invention, can be effectively reduced blood glucose level, have certain protective effect to angiocarpy,
The generation that can prevent disease ensures the health of body.
Above-described embodiment simply to illustrate that the present invention technical concepts and features, it is in the art the purpose is to be to allow
Those of ordinary skill cans understand the content of the present invention and implement it accordingly, and it is not intended to limit the scope of the present invention.It is all
It is the equivalent changes or modifications made according to the essence of the content of present invention, should all covers within the scope of the present invention.
Claims (7)
1. a kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health, it is characterised in that including following each component：Milk powder, shell
Oligosaccharides, xylo-oligosaccharide, dietary fiber and unsaturated fatty acid.
2. a kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health according to claim 1, it is characterised in that packet
Include each component of following weight：98~99.5 parts of milk powder, 0.15~0.25 part of chitosan oligosaccharide, 0.1~0.2 part of xylo-oligosaccharide, diet
0.05~0.15 part of fiber, 0.05~0.15 part of unsaturated fatty acid.
3. a kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health according to claim 1 or 2, it is characterised in that
Include each component of following weight：99.45 parts of milk powder, 0.2 part of chitosan oligosaccharide, 0.15 part of xylo-oligosaccharide, 0.1 part of dietary fiber, no
0.1 part of saturated fatty acid.
4. a kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health according to claim 1, it is characterised in that：Institute
State chitosan oligosaccharide, xylo-oligosaccharide, unsaturated fatty acid purity be 95% or more.
5. a kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health according to claim 1 or 2, feature exist
In：The unsaturated fatty acid is eicosapentaenoic acid.
6. a kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health according to claim 3, it is characterised in that：Institute
It is eicosapentaenoic acid to state unsaturated fatty acid.
7. a kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health according to claim 1, it is characterised in that：Institute
State the composition that milk powder is skimmed milk power or skimmed milk power and whole milk powder.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810050062.1A CN108552320A (en) | 2018-01-18 | 2018-01-18 | A kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health |
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| CN201810050062.1A CN108552320A (en) | 2018-01-18 | 2018-01-18 | A kind of chitosan oligosaccharide milk powder beneficial to middle-aged and the old's cardiovascular health |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112042756A (en) * | 2020-09-16 | 2020-12-08 | 甘肃华羚乳品股份有限公司 | Chitosan oligosaccharide yak milk yoghurt tablet and preparation method thereof |
| CN112244096A (en) * | 2020-10-28 | 2021-01-22 | 江南大学 | Selenium-rich modified milk powder containing probiotics and preparation method thereof |
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| CN102948483A (en) * | 2012-12-03 | 2013-03-06 | 内蒙古伊利实业集团股份有限公司 | Blood fat reducing milk powder and preparation method thereof |
| WO2014132296A1 (en) * | 2013-02-28 | 2014-09-04 | 株式会社ニュートリション・アクト | Powdery yoghurt material and yoghurt making method |
| CN107212097A (en) * | 2017-04-01 | 2017-09-29 | 高培（广州）乳业有限公司 | A kind of milk powder beneficial to middle-aged and old intestinal healths |
-
2018
- 2018-01-18 CN CN201810050062.1A patent/CN108552320A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102948483A (en) * | 2012-12-03 | 2013-03-06 | 内蒙古伊利实业集团股份有限公司 | Blood fat reducing milk powder and preparation method thereof |
| WO2014132296A1 (en) * | 2013-02-28 | 2014-09-04 | 株式会社ニュートリション・アクト | Powdery yoghurt material and yoghurt making method |
| CN107212097A (en) * | 2017-04-01 | 2017-09-29 | 高培（广州）乳业有限公司 | A kind of milk powder beneficial to middle-aged and old intestinal healths |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112042756A (en) * | 2020-09-16 | 2020-12-08 | 甘肃华羚乳品股份有限公司 | Chitosan oligosaccharide yak milk yoghurt tablet and preparation method thereof |
| CN112244096A (en) * | 2020-10-28 | 2021-01-22 | 江南大学 | Selenium-rich modified milk powder containing probiotics and preparation method thereof |
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Application publication date: 20180921 |