CN108522841A - A kind of animals and plants nanometer selenium peptide nutrient solution and preparation method thereof - Google Patents

A kind of animals and plants nanometer selenium peptide nutrient solution and preparation method thereof Download PDF

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Publication number
CN108522841A
CN108522841A CN201810223935.4A CN201810223935A CN108522841A CN 108522841 A CN108522841 A CN 108522841A CN 201810223935 A CN201810223935 A CN 201810223935A CN 108522841 A CN108522841 A CN 108522841A
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nutrient solution
animals
water
selenium
preparation
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Chinese (zh)
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葛明站
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Mudanjiang Ai Li Wei Ya Biotechnology Co Ltd
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Mudanjiang Ai Li Wei Ya Biotechnology Co Ltd
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Priority to CN201810223935.4A priority Critical patent/CN108522841A/en
Publication of CN108522841A publication Critical patent/CN108522841A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C05FERTILISERS; MANUFACTURE THEREOF
    • C05CNITROGENOUS FERTILISERS
    • C05C11/00Other nitrogenous fertilisers
    • CCHEMISTRY; METALLURGY
    • C05FERTILISERS; MANUFACTURE THEREOF
    • C05GMIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS; FERTILISERS CHARACTERISED BY THEIR FORM
    • C05G3/00Mixtures of one or more fertilisers with additives not having a specially fertilising activity

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A kind of animals and plants nanometer selenium peptide nutrient solution and preparation method thereof, is related to a kind of animals and plants nutrient solution and preparation method thereof, and the weight percent proportioning of nutrient solution is:Yeast 20g, L nitrogen propylhomoserin 300g, glucose 90g, sub- selenium receive 10g, glutathione 20g, water 560g.Each component in addition to water is weighed in prescription ratio, and initial sub- sour na concn 10ML/l, shaking table turn 200r/min in fermentation medium, liquid amount 40ml/500ml, 27 DEG C of temperature, initial pH 6.0, with this condition, yeast bio amount reaches 11g/l, and final selenium organic transformation rate is 90.2%, water is added, makes water content up to 55%~60%, refrigeration stands 12 hours, then insoluble impurities is made to precipitate, after taking its supernatant liquid filtering, refrigeration to stand, sterilizing, it is filling.The present invention realizes preparation safety reliable, nonhazardous, noresidue, easy to use, and technology is simple and practicable.

Description

A kind of animals and plants nanometer selenium peptide nutrient solution and preparation method thereof
Technical field
The present invention relates to a kind of animals and plants nutrient solutions and preparation method thereof, allow animals and plants to have richness more particularly to one kind The nanometer selenium peptide nutrient solution and preparation method thereof of selenium effect.
Background technology
With the rapid development of farming and animal husbandry, farming and animal husbandry disease popularity is increasingly frequent, and farming and animal husbandry endures bacterial drug resistance enhancing to the fullest extent, The puzzlements such as the huge increasing of disease prevention and cure cost, cause the interests of peasant household that can not ensure.
The clinical manifestation of animals and plants disease includes animal whole body, airframe systems, organ or morphologic change locally occurs and goes out Existing functional disorder.The part disease of animals and plants selenium deficiency can be transmitted to mankind's zoonosis through a variety of ways would generally be to The health care belt of the mankind carrys out strong influence.And public health may be threatened.
Animals and plants selenium deficiency causes disease in order to prevent, and generality prevents pre- measure by food Selenium Supplement as main source.It is right For plant usually increase selenium element is carried out by using the fertilizer containing selenium element.But from the point of view of most of practices, peasant household It is difficult the dosage for grasping food or fertilizer, cannot effectively plays the role of balanced dynamic plant selenium element.
So enhancing animals and plants selenium element content is most important, animals and plants selenium element is increased with a kind of nanometer selenium peptide nutrient solution Deng more advantageous.
Invention content
The purpose of the present invention is to provide a kind of animals and plants nanometer selenium peptide nutrient solutions and preparation method thereof, and nutrient solution liquid is matched The needs in the markets Fang Shiying can be improved animals and plants body selenium rich ability, prevent secondary infection.Process Quality Control solution is closed Reason realizes reliable preparation safety, nonhazardous, noresidue, easy to use, the simple and practicable feature of technology.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of animals and plants nanometer selenium peptide nutrient solution, the weight percent of the nutrient solution, which matches, is:Yeast 20g, L- nitrogen propylhomoserin 300g, glucose 90g, sub- selenium receive 10g, glutathione 20g, water 560g.
A kind of animals and plants nanometer selenium peptide nutrition liquid and preparation method thereof, the method includes following preparation process:
Each component in addition to water is weighed in prescription ratio, and initial sub- sour na concn 10ML/l, shaking table turn 200r/ in fermentation medium Min, liquid amount 40ml/500ml, 27 DEG C of temperature, initial pH 6.0, with this condition, yeast bio amount reach 11g/l, finally Selenium organic transformation rate is 90.2%, and water is added, and makes water content up to 55%~60%, refrigeration stands 12 hours, then makes insoluble miscellaneous Matter precipitates, and after taking its supernatant liquid filtering, refrigeration to stand, sterilizing is filling.
Advantages of the present invention is with effect:
1. the present invention selects technique centered on the characteristic of effective components of Chinese medicinal, the chemical property in conjunction with active ingredients of plants is stringent Stitch technique, oral solution effective component content made of extract is high, and anti-bacteria and anti-virus potency is high, finally makes the antibacterial of finished product anti- Virus titer is equal to the potency of medicinal material even higher than used.The anti-bacteria and anti-virus medicinal material in Chinese medicine can be directly substituted, due in Medicament extract absorptivity is very high, so being more than 20 grams of raw medicinal herbs powder the effect of 1 gram of extract, the technology for improving product contains Amount, reduces small product size;The antimicrobial component of Chinese herbal medicine is complicated, and bacterium is difficult effectively to be identified to it and generate tolerance, is used for The effect of enhancing Western medicine, and make up the shortcomings that Western medicine is also easy to produce tolerance;It can enhance product tolerance to be mixed with Western medicine, and Increase its curative effect;And it can be individually made anti-bacteria and anti-virus preparation, for treating communicable disease caused by all kinds of bacterial viruses.
It is founded alone according to years'experiences 2. prescription of the present invention is scientific research group, pure Chinese medicine noresidue is safe, And it noresidue, has no toxic side effect.By using said preparation, whole Chinese herb on the prevention to have received good curative effect in cultivation, Chinese medicine is pre- Anti- property drug cost is higher compared with Western medicine, although the disposable drug cost of Chinese medicine is high, the time maintained is more much longer than Western medicine, Not higher than Western medicine or less than Western medicine expenses for medicine from the point of view of average every chicken of whole a collection of chicken.The reasonable recipe, treating both manifestation and root cause of disease are right Virus, moreover, Chinese medicine, which is used for a long time, can improve chicken body premunition, has no drug resistance and stops infected with effect is prevented, treated well The medicine phase.
3. drug used in the present invention have enhance or adjust body non-specific immune function and specific immune function, Anti-inflammatory, it is antiviral, enhancing digestive system function the effects that, so that the constitution of chicken is enhanced.It is shown experimentally that in layer breeding process Middle to be prevented after drinking water using the traditional Chinese medicine oral liquid, control group chicken feeds basal diet;Whole observational record each group chicken daily output Egg amount, egg size, feed intake have increase, incidence, broken egg number, the death rate to have decline.Test group chicken experimental period total earnings ratio Control group increases average every chicken and takes in 1.03-2.20 members more;Economic benefit improves 13.0%-26.6%.Invention formulation with it is anti- The contrast test that raw element class drug uses during broiler feeding, the results showed that broiler growth, survival rate and feed conversion rate Respectively 5.1%, 8.2% and 4.5% is improved than antibiotic group.Proof has no adverse effects to the growth of Broiler chicks, test chicken appetite Vigorous, feather smooth-going, weight is relatively uniform, is in a good state of health, and improves 20% or more survival rate.It is outer in the spirit of chicken group Sight, mental status, the uniformity, chicken fur color and luster be all substantially better than control group.
Specific implementation mode
The following describes the present invention in detail with reference to examples.
Specific synthesis process:Each ingredient in addition to water is weighed in prescription ratio, including following weight percent is matched Yeast 20g, L- nitrogen propylhomoserin 300g of square component, glucose 90g, sub- selenium receive 10g, glutathione 20g, water 560g.Utilize yeast The influence of cell growth and selenium rich ability carries out orthogonal test on the basis of experiment of single factor, obtains preferably yeast life Object, the environmental condition that yeast bio converts inorganic selenium are:Initial sub- sour na concn 10ML/l, shaking speed in fermentation medium 200r/min, liquid amount 40ml/500ml, 27 DEG C of temperature, initial pH 6.0, with this condition, yeast bio amount reach 11g/ L, final selenium organic transformation rate are 90.2%, and water is added, and make water content up to 55%~60%, refrigeration stands 12 hours, then makes not Solubility impurity precipitates, and takes its supernatant liquid filtering, takes out filtering, and refrigeration stands 24 hours, filling, and sterilizing is to get appearance character The nutrient solution of milky clear liquid.

Claims (2)

1. a kind of animals and plants nanometer selenium peptide nutrient solution, which is characterized in that the weight percent of the nutrient solution, which matches, is:Yeast 20g, L- nitrogen propylhomoserin 300g, glucose 90g, sub- selenium receive 10g, glutathione 20g, water 560g.
2. a kind of animals and plants nanometer selenium peptide nutrition liquid and preparation method thereof, which is characterized in that the method includes following preparation process:
Each component in addition to water is weighed in prescription ratio, and initial sub- sour na concn 10ML/l, shaking table turn 200r/ in fermentation medium Min, liquid amount 40ml/500ml, 27 DEG C of temperature, initial pH 6.0, with this condition, yeast bio amount reach 11g/l, finally Selenium organic transformation rate is 90.2%, and water is added, and makes water content up to 55%~60%, refrigeration stands 12 hours, then makes insoluble miscellaneous Matter precipitates, and after taking its supernatant liquid filtering, refrigeration to stand, sterilizing is filling.
CN201810223935.4A 2018-03-19 2018-03-19 A kind of animals and plants nanometer selenium peptide nutrient solution and preparation method thereof Pending CN108522841A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102860408A (en) * 2012-09-24 2013-01-09 江西昌丰由由生物科技有限公司 Preparation method of multifunctional live microorganism preparation for forage
CN106119139A (en) * 2016-06-21 2016-11-16 南京农业大学 A kind of selenium-rich produces glutathion compound bacteria and its preparation method and application
CN106387317A (en) * 2016-08-31 2017-02-15 上海绿博生物科技发展有限公司 Microorganism feed additive capable of protecting pig livers and preparation method of microorganism feed additive
CN106801069A (en) * 2017-01-22 2017-06-06 广州天科生物科技有限公司 Nano selenium and preparation method thereof
CN107624953A (en) * 2017-08-31 2018-01-26 北京二商生物科技有限公司 A kind of preparation method of selenium-rich high protein activated peptide as additive

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102860408A (en) * 2012-09-24 2013-01-09 江西昌丰由由生物科技有限公司 Preparation method of multifunctional live microorganism preparation for forage
CN106119139A (en) * 2016-06-21 2016-11-16 南京农业大学 A kind of selenium-rich produces glutathion compound bacteria and its preparation method and application
CN106387317A (en) * 2016-08-31 2017-02-15 上海绿博生物科技发展有限公司 Microorganism feed additive capable of protecting pig livers and preparation method of microorganism feed additive
CN106801069A (en) * 2017-01-22 2017-06-06 广州天科生物科技有限公司 Nano selenium and preparation method thereof
CN107624953A (en) * 2017-08-31 2018-01-26 北京二商生物科技有限公司 A kind of preparation method of selenium-rich high protein activated peptide as additive

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Title
傅善来: "《补硒治未病》", 31 October 2009, 上海科技教育出版社 *
姜锡瑞: "《生物发酵产业技术》", 31 May 2016, 中国轻工业出版社 *
钱洪彬等: "酵母硒对热应激致育肥猪氧化损伤保护作用的研究", 《中国畜牧兽医文摘》 *
韦建福: "还原型谷胱甘肽对肉鸡生长及血清ICF-1水平、组织IGF-1 mRNA表达的影响", 《中国兽医学报》 *

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Application publication date: 20180914