CN108514590A - It is a kind of to be used to treat Chinese patent drug of diabetes and preparation method thereof - Google Patents

It is a kind of to be used to treat Chinese patent drug of diabetes and preparation method thereof Download PDF

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Publication number
CN108514590A
CN108514590A CN201810472103.6A CN201810472103A CN108514590A CN 108514590 A CN108514590 A CN 108514590A CN 201810472103 A CN201810472103 A CN 201810472103A CN 108514590 A CN108514590 A CN 108514590A
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parts
radix notoginseng
oyster
chinese patent
matrimony vine
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CN201810472103.6A
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Chinese (zh)
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廖和平
廖春阳
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese patent drugs and preparation method thereof for treating diabetes, and raw material includes oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit, water.The present invention provides a kind of for treating Chinese patent drug of diabetes and preparation method thereof, has no toxic side effect, can reduce blood glucose, blood pressure, blood fat etc. and make it restore to normal level and alleviate phenomena such as blood is viscous, to comprehensive reduction and block the various complication of diabetes.

Description

It is a kind of to be used to treat Chinese patent drug of diabetes and preparation method thereof
Technical field
The present invention relates to treating diabetes field, specially a kind of Chinese patent drug and its preparation sides for treating diabetes Method.
Background technology
Diabetes are the metabolic diseases characterized by hyperglycemia, and with the excessively high disease such as blood pressure, blood fat and blood is viscous Shape seriously endangers the health of people;The method that there is no radical cure diabetes at present, but can be carried out by means such as oral drugs There is costly and easily adverse reaction in control, existing Western medicine price.
Invention content
The present invention using Chinese herbal medicines combination anticancer theory, provide it is a kind of for treat diabetes Chinese patent drug and its Preparation method, according to traditional Chinese medical science prescription theory, extraction Chinese medicine essence is used for the control of diabetes, and toxic side effect is small.
Raw material of the present invention includes oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit;The above components are with parts by weight Meter is respectively:5~20 parts of oyster, 10~30 parts of Herba Epimedii, 8~25 parts of matrimony vine, 5~25 parts of the root bark of white mulberry, 5~30 parts of Radix Notoginseng, Gorgon euryale Real 3~15 parts, 200~500 parts of water.
Preferably, each component is respectively in terms of parts by weight:12 parts of oyster, 20 parts of Herba Epimedii, 15 parts of matrimony vine, Sang Bai 15 parts of skin, 12 parts of Radix Notoginseng, 10 parts of Gorgon fruit, 300 parts of water.
Preferably, the oyster is oyster shell powder.
Preferably, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit are powdered.
Preferably, in order to improve drug effect, the matrimony vine uses lycium barbarum, the Radix Notoginseng to use mountain of papers Radix Notoginseng.
A kind of preparation method for treating the Chinese patent drug of diabetes includes the following steps:
1)Raw material preparation:Oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit are cleaned and are rolled into powder after drying;
2)Base fluid takes:Oyster is added to the water and is stirred rear big fire to boiled rear slow boiling tanning 30min;
3)Raw material mixes:By in step 1 Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder be added into the base in step 2 In liquid and 3h is stirred so that semi-finished product medicine is made;
4)Patent medicine makes:Finished product is made in semi-finished product medicine drying in step 3.
Preferably, the oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder size be 50~150 mesh.
Preferably, the finished product is pill or powder or tablet.
Advantageous effect
The present invention utilizes the theory that Chinese medicine negative and positive reconcile, and using Chinese herbal medicines combined therapy diabetes, provides a kind of for controlling The Chinese patent drug of diabetes is treated, raw material have oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit;Wherein oyster and Radix Notoginseng can Supplementing qi and nourishing yin lets out turbid removing toxic substances;Matrimony vine, the root bark of white mulberry and Gorgon fruit being capable of help qi-regulating, kidney and spleen invigoratings;Herba Epimedii can strengthening the essence gas and add The drug effect of strong other medicines;The helps qi-regulating such as blood glucose, blood pressure, blood fat can be reduced and make it restore to normal level and alleviate blood and glued Phenomena such as;And using the function point analysis human body for letting out turbid removing toxic substances and help qi-regulating of oyster, Herba Epimedii, matrimony vine etc., prevent diabetes People's renal failure.
1, in preparation process, oyster tanning 30min makes the pharmacological property molecule in oyster fully be dissolved in water, then will be excessive The sheep leaves of pulse plants, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder be added in the base fluid being brewed into oyster and stir 3h, in whipping process Can continue heat base fluid, make its temperature keep 60~80 DEG C so that in base fluid oyster molecule be thoroughly impregnated to Herba Epimedii, matrimony vine, The root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder in, so that each drug component gives full play to synergistic effect.
2, it is parts of generic medicinal plants using natural animal-plant medicinal material, safe without toxic side effect, and raw material, materials are easy, Required expense is few.
3, preparation method is simple, will not increase the burden of user.
Description of the drawings
Fig. 1 is blood sugar test data before part is taken medicine.
Fig. 2 is glycosylated hemoglobin test data before part is taken medicine.
Fig. 3 is clinical testing data after part is taken medicine.
Specific implementation mode
Embodiment 1:A kind of Chinese patent drug for treating diabetes, including following components in parts by weight:5 parts of oyster, excessive sheep 10 parts of the leaves of pulse plants, 8 parts of matrimony vine, 5 parts of the root bark of white mulberry, 5 parts of Radix Notoginseng, 3 parts of Gorgon fruit, 200 parts of water.
The oyster is oyster shell powder, and the Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit are powdered;The Chinese holly Qi uses lycium barbarum, the Radix Notoginseng to use mountain of papers Radix Notoginseng.
A kind of preparation method for treating the Chinese patent drug of diabetes includes the following steps:
1)Raw material preparation:Oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit are cleaned and are rolled into powder after drying;
2)Base fluid takes:Oyster is added to the water and is stirred rear big fire to boiled rear slow boiling tanning 30min;
3)Raw material mixes:By in step 1 Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder be added into the base in step 2 In liquid and stirs 3h semi-finished product medicine is made;
4)Patent medicine makes:Tablet is made in semi-finished product medicine drying in step 3.
The oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder size be 50 mesh.
Embodiment 2:A kind of Chinese patent drug for treating diabetes, including following components in parts by weight:20 parts of oyster, excessive sheep 30 parts of the leaves of pulse plants, 25 parts of matrimony vine, 25 parts of the root bark of white mulberry, 30 parts of Radix Notoginseng, 15 parts of Gorgon fruit, 500 parts of water.
The oyster is oyster shell powder, and the Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit are powdered;The Chinese holly Qi uses lycium barbarum, the Radix Notoginseng to use mountain of papers Radix Notoginseng.
A kind of preparation method for treating the Chinese patent drug of diabetes includes the following steps:
1)Raw material preparation:Oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit are cleaned and are rolled into powder after drying;
2)Base fluid takes:Oyster is added to the water and is stirred rear big fire to boiled rear slow boiling tanning 30min;
3)Raw material mixes:By in step 1 Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder be added into the base in step 2 In liquid and 3h is stirred so that semi-finished product medicine is made;
4)Patent medicine makes:Powder is made in semi-finished product medicine drying in step 3.
The oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder size be 150 mesh.
Embodiment 3:12 parts of oyster, 20 parts of Herba Epimedii, 15 parts of matrimony vine, 15 parts of the root bark of white mulberry, 12 parts of Radix Notoginseng, 10 parts of Gorgon fruit, water 300 parts.
The oyster is oyster shell powder, and the Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit are powdered;The Chinese holly Qi uses lycium barbarum, the Radix Notoginseng to use mountain of papers Radix Notoginseng.
A kind of preparation method for treating the Chinese patent drug of diabetes includes the following steps:
1)Raw material preparation:Oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit are cleaned and are rolled into powder after drying;
2)Base fluid takes:Oyster is added to the water and is stirred rear big fire to boiled rear slow boiling tanning 30min;
3)Raw material mixes:By in step 1 Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder be added into the base in step 2 In liquid and stirs 3h semi-finished product medicine is made;
4)Patent medicine makes:Pill is made in semi-finished product medicine drying in step 3.
The oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder size be 100 mesh.
The present inventor studies Chinese herbal medicine for many years, finally has developed the Chinese patent drug of the present invention, as a treatment course with two months, often Day twice, takes after the meal;Since research and development, it has repeatedly been used for clinical treatment, according to the individual difference of ward mate's state of an illness, is advised in parts by weight Determine, than adjusting in range, multidigit ward mate to be helped to get well.
Partial clinical test data is listed as follows:
Detailed Jie has been carried out to a kind of Chinese patent drug and preparation method thereof for treating diabetes provided by the present invention above It continues, principle and implementation of the present invention are described herein, and the explanation of above example is only intended to help to understand The method of the present invention is with its core concept;Meanwhile for those of ordinary skill in the art, according to the thought of the present invention, having There will be changes in body embodiment and application range, in conclusion the content of this specification should not be construed as to this hair Bright limitation.

Claims (9)

1. a kind of for treating the Chinese patent drugs of diabetes, which is characterized in that raw material include oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit, water;The above components in terms of parts by weight be respectively:5~20 parts of oyster, 10~30 parts of Herba Epimedii, matrimony vine 8~ 25 parts, 5~25 parts of the root bark of white mulberry, 5~30 parts of Radix Notoginseng, 3~15 parts of Gorgon fruit, 200~500 parts of water.
2. a kind of Chinese patent drug for treating diabetes according to claim 1, which is characterized in that each component is with weight Measuring number meter is respectively:12 parts of oyster, 20 parts of Herba Epimedii, 15 parts of matrimony vine, 15 parts of the root bark of white mulberry, 12 parts of Radix Notoginseng, 10 parts of Gorgon fruit, water 300 parts.
3. a kind of Chinese patent drug for treating diabetes according to claim 1, which is characterized in that the oyster is oyster Shell powder.
4. a kind of Chinese patent drug for treating diabetes according to claim 1, which is characterized in that Herba Epimedii, matrimony vine, mulberry White skin, Radix Notoginseng, Gorgon fruit are powdered.
5. a kind of Chinese patent drug for treating diabetes according to claim 1, which is characterized in that the matrimony vine is using peaceful Summer matrimony vine.
6. a kind of Chinese patent drug for treating diabetes according to claim 1, which is characterized in that the Radix Notoginseng is using text Mountain Radix Notoginseng.
7. any one according to claim 1-6 is used to treat the preparation method of the Chinese patent drug of diabetes, feature exists In including the following steps:
Raw material preparation:Oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit are cleaned and are rolled into powder after drying;
Base fluid takes:Oyster is added to the water and is stirred, big fire to boiled rear slow boiling boils 30min;
Raw material mixes:By in step 1 Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit powder be added into the base fluid in step 2 In and stir 3h so that semi-finished product medicine is made;
Patent medicine makes:Finished product is made in semi-finished product medicine drying in step 3.
8. a kind of Chinese patent drug preparation method for treating diabetes according to claim 7, which is characterized in that step 1 Described in oyster, Herba Epimedii, matrimony vine, the root bark of white mulberry, Radix Notoginseng, Gorgon fruit, powder size be 50~150 mesh.
9. according to claim 7 a kind of for treating the Chinese patent drug preparation methods of diabetes, which is characterized in that it is described at Product are pill or powder or tablet.
CN201810472103.6A 2018-05-17 2018-05-17 It is a kind of to be used to treat Chinese patent drug of diabetes and preparation method thereof Pending CN108514590A (en)

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CN201810472103.6A CN108514590A (en) 2018-05-17 2018-05-17 It is a kind of to be used to treat Chinese patent drug of diabetes and preparation method thereof

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CN201810472103.6A CN108514590A (en) 2018-05-17 2018-05-17 It is a kind of to be used to treat Chinese patent drug of diabetes and preparation method thereof

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102793794A (en) * 2011-05-27 2012-11-28 董根荣 Medicinal composition for treating diabetes mellitus and preparation method thereof
CN106265972A (en) * 2015-05-13 2017-01-04 蒋蓉 A kind of Chinese patent medicine treating diabetic impotence

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102793794A (en) * 2011-05-27 2012-11-28 董根荣 Medicinal composition for treating diabetes mellitus and preparation method thereof
CN106265972A (en) * 2015-05-13 2017-01-04 蒋蓉 A kind of Chinese patent medicine treating diabetic impotence

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Application publication date: 20180911