CN108498329A - A kind of blood bag - Google Patents
A kind of blood bag Download PDFInfo
- Publication number
- CN108498329A CN108498329A CN201810438434.8A CN201810438434A CN108498329A CN 108498329 A CN108498329 A CN 108498329A CN 201810438434 A CN201810438434 A CN 201810438434A CN 108498329 A CN108498329 A CN 108498329A
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- CN
- China
- Prior art keywords
- subsidence part
- blood
- width
- subsidence
- centrifugal sedimentation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 67
- 239000008280 blood Substances 0.000 title claims abstract description 67
- 238000004062 sedimentation Methods 0.000 claims abstract description 67
- 210000001772 blood platelet Anatomy 0.000 claims abstract description 24
- 210000003743 erythrocyte Anatomy 0.000 claims abstract description 19
- 210000002381 plasma Anatomy 0.000 claims abstract description 17
- 239000004615 ingredient Substances 0.000 abstract description 3
- 239000000463 material Substances 0.000 description 11
- 238000000034 method Methods 0.000 description 6
- 239000004593 Epoxy Substances 0.000 description 5
- 239000004014 plasticizer Substances 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- -1 Polyethylene Polymers 0.000 description 3
- 235000021355 Stearic acid Nutrition 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 238000007599 discharging Methods 0.000 description 3
- 239000000314 lubricant Substances 0.000 description 3
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 3
- 239000004800 polyvinyl chloride Substances 0.000 description 3
- 229920000915 polyvinyl chloride Polymers 0.000 description 3
- 239000008117 stearic acid Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- QZCLKYGREBVARF-UHFFFAOYSA-N Acetyl tributyl citrate Chemical compound CCCCOC(=O)CC(C(=O)OCCCC)(OC(C)=O)CC(=O)OCCCC QZCLKYGREBVARF-UHFFFAOYSA-N 0.000 description 2
- ZFOZVQLOBQUTQQ-UHFFFAOYSA-N Tributyl citrate Chemical compound CCCCOC(=O)CC(O)(C(=O)OCCCC)CC(=O)OCCCC ZFOZVQLOBQUTQQ-UHFFFAOYSA-N 0.000 description 2
- CEGOLXSVJUTHNZ-UHFFFAOYSA-K aluminium tristearate Chemical group [Al+3].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CEGOLXSVJUTHNZ-UHFFFAOYSA-K 0.000 description 2
- 229940063655 aluminum stearate Drugs 0.000 description 2
- 239000002518 antifoaming agent Substances 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 125000003700 epoxy group Chemical group 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 238000003306 harvesting Methods 0.000 description 2
- 239000012760 heat stabilizer Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- 229920000647 polyepoxide Polymers 0.000 description 2
- 239000004626 polylactic acid Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 1
- 239000004808 2-ethylhexylester Substances 0.000 description 1
- 239000004804 Butyryltrihexylcitrate Substances 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 229920001612 Hydroxyethyl starch Polymers 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- YSMRWXYRXBRSND-UHFFFAOYSA-N TOTP Chemical compound CC1=CC=CC=C1OP(=O)(OC=1C(=CC=CC=1)C)OC1=CC=CC=C1C YSMRWXYRXBRSND-UHFFFAOYSA-N 0.000 description 1
- KRADHMIOFJQKEZ-UHFFFAOYSA-N Tri-2-ethylhexyl trimellitate Chemical compound CCCCC(CC)COC(=O)C1=CC=C(C(=O)OCC(CC)CCCC)C(C(=O)OCC(CC)CCCC)=C1 KRADHMIOFJQKEZ-UHFFFAOYSA-N 0.000 description 1
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- SAOKZLXYCUGLFA-UHFFFAOYSA-N bis(2-ethylhexyl) adipate Chemical compound CCCCC(CC)COC(=O)CCCCC(=O)OCC(CC)CCCC SAOKZLXYCUGLFA-UHFFFAOYSA-N 0.000 description 1
- HORIEOQXBKUKGQ-UHFFFAOYSA-N bis(7-methyloctyl) cyclohexane-1,2-dicarboxylate Chemical compound CC(C)CCCCCCOC(=O)C1CCCCC1C(=O)OCCCCCCC(C)C HORIEOQXBKUKGQ-UHFFFAOYSA-N 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- DPDORTBBLUCNJG-UHFFFAOYSA-N calcium tin Chemical compound [Ca].[Sn] DPDORTBBLUCNJG-UHFFFAOYSA-N 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 231100000433 cytotoxic Toxicity 0.000 description 1
- 230000001472 cytotoxic effect Effects 0.000 description 1
- 230000003013 cytotoxicity Effects 0.000 description 1
- 231100000135 cytotoxicity Toxicity 0.000 description 1
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 description 1
- 239000004806 diisononylester Substances 0.000 description 1
- BJAJDJDODCWPNS-UHFFFAOYSA-N dotp Chemical compound O=C1N2CCOC2=NC2=C1SC=C2 BJAJDJDODCWPNS-UHFFFAOYSA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 229940050526 hydroxyethylstarch Drugs 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000000944 linseed oil Substances 0.000 description 1
- 235000021388 linseed oil Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 238000005374 membrane filtration Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052901 montmorillonite Inorganic materials 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 229920001921 poly-methyl-phenyl-siloxane Polymers 0.000 description 1
- 229920001610 polycaprolactone Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- GZCWPZJOEIAXRU-UHFFFAOYSA-N tin zinc Chemical compound [Zn].[Sn] GZCWPZJOEIAXRU-UHFFFAOYSA-N 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 239000001069 triethyl citrate Substances 0.000 description 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- GWVUTNGDMGTPFE-UHFFFAOYSA-N trihexyl 2-butanoyloxypropane-1,2,3-tricarboxylate Chemical compound CCCCCCOC(=O)CC(C(=O)OCCCCCC)(OC(=O)CCC)CC(=O)OCCCCCC GWVUTNGDMGTPFE-UHFFFAOYSA-N 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
- A61J1/1425—Snap-fit type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1468—Containers characterised by specific material properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses a kind of blood bags.The blood bag, in centrifugal sedimentation, blood is placed in the blood bag, after centrifugal sedimentation, blood plasma is collected by the first subsidence part, and blood platelet, leucocyte are collected by the second subsidence part, red blood cell is collected by third subsidence part so that each ingredient thus isolated has higher purity, has higher separative efficiency.
Description
Technical field
The present invention relates to the technical fields of Blood Sedimentation device, in particular to a kind of blood bag.
Background technology
Currently, blood platelet, leucocyte extraction element are usually test tube, centrifuge tube or blood bag, if being used using these devices
Dry subgradient centrifugal process obtains blood platelet, the leucocyte of certain purity, or the sedimentation agents such as hydroxyethyl starch are added in blood
Auxiliary obtains.
In the prior art, blood platelet, the purity of leucocyte and inefficient are extracted in centrifugal sedimentation using blood bag, it is main
The reason is that after blood cell sedimentation separation, the blood platelet of formation, leucocyte interface are too thin, can not further with red blood cell etc. effectively point
From causing operating procedure complicated, red blood cell etc. is easily mixed into, blood platelet, the problems such as leucocyte is easy to be lost, or even has to use one
A little cytotoxic additives, such as gradient centrifugation is assisted using lymphocyte separation medium chemical substance, it needs to be centrifuged repeatedly
Washing removes the separating liquid, can be only achieved and mitigates cytotoxicity, safe separating purpose.But therefore cause the time-consuming expense of operating process
Power, blood platelet, leucocyte harvest quantity or quality be not high.Also useful membrane filtration method harvest blood platelet, leucocyte, but because
It needs to rinse repeatedly.
Invention content
In view of this, the embodiment of the present invention is designed to provide a kind of blood bag, using the blood bag energy greater efficiency and compared with
Centrifugal sedimentation is carried out to high-purity to blood.
A kind of blood bag is used for the centrifugal sedimentation of blood, including bag body, and the bag body includes one first subsidence part, for passing through
Blood plasma is collected after the centrifugal sedimentation；One second subsidence part, for collecting blood platelet, leucocyte after the centrifugal sedimentation；One
Third subsidence part, for collecting red blood cell after the centrifugal sedimentation；The both ends of second subsidence part are respectively communicated with described
One subsidence part and third subsidence part.
Further, the width of first subsidence part is more than the width of second subsidence part.
Further, the width of the third subsidence part is more than the width of second subsidence part.
Further, the width of first subsidence part is more than the width of the third subsidence part.
Further, first subsidence part is taper.
Further, the third subsidence part is elliposoidal.
Further, second subsidence part is vertical bar shaped.
Further, second subsidence part is communicated with outlet and inlet tube.
Further, the internal diameter of the inlet tube is more than the outlet.
Further, the bag body is additionally provided with overlap, and the overlap offers suppending hole.
The blood bag of the present invention, in centrifugal sedimentation, blood is placed in the blood bag, and after centrifugal sedimentation, blood plasma is by the first sedimentation
Portion is collected, and blood platelet, leucocyte are collected by the second subsidence part, and red blood cell is collected by third subsidence part so that is thus isolated
Each ingredient has higher purity, has higher separative efficiency.
To enable the above objects, features and advantages of the present invention to be clearer and more comprehensible, preferred embodiment cited below particularly, and coordinate
Appended attached drawing, is described in detail below.
Description of the drawings
In order to illustrate the technical solution of the embodiments of the present invention more clearly, below will be to needed in the embodiment attached
Figure is briefly described, it should be understood that the following drawings illustrates only certain embodiments of the present invention, therefore is not construed as pair
The restriction of range for those of ordinary skill in the art without creative efforts, can also be according to this
A little attached drawings obtain other relevant attached drawings.
Fig. 1 shows a viewing angle constructions figure of the blood bag that the embodiment of the present invention is provided.
Main element symbol description：
100 blood bags
20 bags of bodies
21 first subsidence parts
22 second subsidence parts
23 third subsidence parts
30 outlets
40 inlet tubes
50 overlaps
51 suppending holes.
Specific implementation mode
To facilitate the understanding of the present invention, blood bag is described more fully below with reference to relevant drawings.It is given in attached drawing
The preferred embodiment of blood bag is gone out.But blood bag can be realized in many different forms, however it is not limited to described herein
Embodiment.Keep the disclosure to blood bag more thorough and comprehensive on the contrary, purpose of providing these embodiments is.
In the description of the present invention, it is to be understood that, term " longitudinal direction ", " transverse direction ", "upper", "lower", "front", "rear",
The orientation or positional relationship of the instructions such as "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside" is based on attached drawing institute
The orientation or positional relationship shown, is merely for convenience of description of the present invention and simplification of the description, and does not indicate or imply the indicated dress
It sets or element must have a particular orientation, with specific azimuth configuration and operation, therefore should not be understood as the limit to the present invention
System.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example
Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not
Centainly refer to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be any
One or more embodiments or example in can be combined in any suitable manner.
In the description of the present invention, unless otherwise specified and limited, it should be noted that term " installation ", " connected ",
" connection " shall be understood in a broad sense, for example, it may be mechanical connection or electrical connection, can also be the connection inside two elements, it can
, can also indirectly connected through an intermediary, for the ordinary skill in the art to be to be connected directly, it can basis
Concrete condition understands the concrete meaning of above-mentioned term.
It please refers to Fig.1.The blood bag 100 of the embodiment of the present invention is used for the centrifugal sedimentation of blood, including bag body 20, this bag of body
20 include one first subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for through the centrifugation
Blood platelet, leucocyte are collected after sedimentation；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；This is second heavy
The both ends in drop portion 22 are respectively communicated with the first subsidence part 21 and third subsidence part 23.
In above-described embodiment, in centrifugal sedimentation, blood is first placed in the blood bag 100.After centrifugal sedimentation, blood plasma is by
One subsidence part 21 is collected, and blood platelet, leucocyte are collected by the second subsidence part 22, and red blood cell is collected by third subsidence part 23 so that
Thus each ingredient isolated has higher purity, has higher separative efficiency.
Note that above-mentioned first subsidence part 21, the second subsidence part 22 and third subsidence part 23 can be integration connection.
It should be apparent that placement status of the above-mentioned blood bag 100 in centrifugal sedimentation is so that bag body 20 is in vertical, i.e., the
One subsidence part 21 is located above, the second subsidence part 22 is located at intermediate, third subsidence part 23 and is located at bottom.Herein, upper and lower, in
Between refer to straight down, i.e., under being pointed by gravitational vectors.
The both ends of second subsidence part 22 are respectively communicated with first subsidence part 21 and third subsidence part 23, may be used directly
The mode of connection, the i.e. internal cavities of the second subsidence part 22 are connected with the internal cavities of the first subsidence part 21, the second subsidence part
22 internal cavities are connected with the internal cavities of third subsidence part 23, rather than by the way that outlet connection is arranged in the second subsidence part 22
Structure connects.
General material, such as PVC material can be used in blood bag 100, can enumerate a kind of material of PVC material blood bag 100
Composition, it is other to include the following components'mass percentage：15~50% plasticizer, 0.5~5% stabilizer, 0.l~1% lubricate
The polyvinyl chloride resin that agent and the degree of polymerization are 700~3000.Plasticizer is GOMGHA, ATBC, DINCH, DOA, BTHC, TOTM, DOTP
One or more of.Stabilizer includes 30~75wt% epoxies quasi-grease and 25~50wt% bimetallic salt complexs, epoxies oil
Fat is the appropriate youngster's oil of epoxidized soybean oil, epoxy, epoxy linseed oil, and one or more of in epoxy monoglyceride, bimetallic salt complex is calcium-
One or more of zinc, tin-zinc, tin-calcium.Lubricant includes lipoid substance, and lipoid substance is polymethylphenyl siloxane fluid, oxidation
Polyethylene wax, stearic acid polyol ester, one in high carbon acid polyacid/alcohol complex ester, stearic acid or adipic acid pentaerythritol ester
Kind is several.Certainly it is based on the purpose of environmental protection, blood bag 100 can also be used degradable material, such as biodegradable material, herein may be used
A kind of 100 material of biodegradable blood bag is enumerated, very includes 60~90% polylactic acid, 0~10% according to quality
Poly-epsilon-caprolactone, 0~20% lactic acid-epsilon-caprolactone copolymer, 2~20% medical plasticizer, 0~0.2% antifoaming agent, 0~
0.1% stearic acid lubricant, 0~5% heat stabilizer, 0~3% montmorillonite, the wherein average molecular weight of polylactic acid be 4~
1500000, glass temperature range be 40~60 DEG C, medical plasticizer be acetyl tri-n-butyl citrate, tri-n-butyl citrate,
Any one of triethyl citrate, polyethylene glycol or two or more mixtures, antifoaming agent are methyl-silicone oil or tricresyl phosphate fourth
Ester；Heat stabilizer is matched for maleic acid or epoxidized soybean oil；Lubricant is aluminum stearate or aluminum stearate.
In yet another embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.
In this embodiment, width refers to that (horizontal direction refers to perpendicular to gravity side to length angle value in the horizontal direction
To).The width maximum of first subsidence part 21 can with 65~75mm, such as 65mm, 66mm, 68mm, 70mm, 72mm, 75mm etc.,
Note that herein maximum refer to the first subsidence part 21 be non-uniform shapes, such as the case where taper described hereinafter for.Second
Subsidence part 22 is 3~5mm, such as 3mm, 3.5mm, 4mm, 4.2mm, 4.5mm or 5mm etc..
In a further embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.The width of third subsidence part 23 is more than the width of second subsidence part 22.
In this embodiment, the width maximum of third subsidence part 23 can be 12~20mm, such as 12mm, 13mm,
15mm, 16mm, 18mm or 20mm etc..Note that it is non-uniform shapes that maximum, which refers to third subsidence part 23, herein, as described later
Ellipse.
In yet another embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.The width of third subsidence part 23 is more than the width of second subsidence part 22.The width of first subsidence part 21 is more than described the
The width of three subsidence parts 23.
In this embodiment, the width of third subsidence part 23 can be 3~5 times of the width of the second subsidence part 22, such as 3
Again, 3.2 times, 3.5 times, 4 times, 4.5 times, 4.8 times or 5 times；The width of first subsidence part 21 can be the 3~5 of third subsidence part 23
Times, such as 3 times, 3.2 times, 3.5 times, 4 times, 4.5 times, 4.8 times or 5 times.
In a further embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.The width of third subsidence part 23 is more than the width of second subsidence part 22.The width of first subsidence part 21 is more than described the
The width of three subsidence parts 23.First subsidence part 21 is taper.
In this embodiment, the taper of the first subsidence part 21 can be form well known to cone, square cone etc..It needs
It is bright, herein taper and only refer to it is geometric by triangle, circle, trapezoidal rotate obtained circle around certain fixation straight line
The rotary body and the geometric frustum of a pyramid (being intercepted obtained by the pyramid with pyramid bottom surface parallel surface) of cone or the frustum of a cone, also
Cover combined by cylindricality and cone.The taper of first subsidence part 21 is taper wide at the top and narrow at the bottom, i.e., close to the second subsidence part
The width of 22 positions is less than the width far from 22 position of the second subsidence part.
In yet another embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.The width of third subsidence part 23 is more than the width of second subsidence part 22.The width of first subsidence part 21 is more than described the
The width of three subsidence parts 23.First subsidence part 21 is taper.Third subsidence part 23 is elliposoidal.
In this embodiment, the elliposoidal of third subsidence part 23 refers to that semiellipse is rotated about their axes obtained rotary body three
Tie up body.Certainly in a further embodiment, third subsidence part 23 can also be kidney ellipsoid, oblate spheroid etc..
In yet another embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.The width of third subsidence part 23 is more than the width of second subsidence part 22.The width of first subsidence part 21 is more than described the
The width of three subsidence parts 23.First subsidence part 21 is taper.Third subsidence part 23 is elliposoidal.Second subsidence part 22 is vertical bar
Shape.
In this embodiment, " bar shaped " refers to the shape that length is much larger than width, and two long sides (corresponding to length) are flat
Row or general parallel orientation.As an implementation, bar shape is straight bar-shaped trough.The two of " straight bar shape " finger body herein
Long side is straight line.As another embodiment, bar shape is that two long sides of arc bar shape finger body are arc
Shape, such as circular arc or elliptic arc etc..
In a further embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.The width of third subsidence part 23 is more than the width of second subsidence part 22.The width of first subsidence part 21 is more than described the
The width of three subsidence parts 23.First subsidence part 21 is taper.Third subsidence part 23 is elliposoidal.Second subsidence part 22 is vertical bar
Shape.Second subsidence part 22 is communicated with outlet 30 and inlet tube 40.
In this embodiment, inlet tube 40 is for being passed through the blood for waiting for centrifugal sedimentation into bag body 20；Outlet 30 is used for
By in bag body 20 it is separated go out blood plasma or red blood cell or blood platelet, leucocyte discharge bag body 20.Outlet 30 can be located at
The top of inlet tube 40, outlet 30 can be located proximate to 22 connectivity part of the first subsidence part 21 and the second subsidence part, inlet tube 40
It can be located proximate to 22 connectivity part of third subsidence part 23 and the second subsidence part.
In yet another embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.The width of third subsidence part 23 is more than the width of second subsidence part 22.The width of first subsidence part 21 is more than described the
The width of three subsidence parts 23.First subsidence part 21 is taper.Third subsidence part 23 is elliposoidal.Second subsidence part 22 is vertical bar
Shape.Second subsidence part 22 is communicated with outlet 30 and inlet tube 40.The internal diameter of inlet tube 40 is more than the outlet 30.
In this embodiment, the internal diameter of inlet tube 40 can be 1.4~2 times of 30 internal diameter of outlet, for example, 1.4 times, 1.5
Again, 1.7 times, 1.8 times, 1.9 times or 2 times etc..
In a further embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.The width of third subsidence part 23 is more than the width of second subsidence part 22.The width of first subsidence part 21 is more than described the
The width of three subsidence parts 23.First subsidence part 21 is taper.Third subsidence part 23 is elliposoidal.Second subsidence part 22 is vertical bar
Shape.Second subsidence part 22 is communicated with outlet 30 and inlet tube 40.The internal diameter of inlet tube 40 is more than the outlet 30.Bag body 20
It is additionally provided with overlap 50, the overlap 50 offers suppending hole 51.
In this embodiment, overlap 50 can be bar shaped, such as ring bar shaped, can surround the periphery of bag body 20.Overlap 50
It can be used and 100 same material of blood bag or other materials.Suppending hole 51, which is used for realizing, hangs on holder or similar structures,
Can be one or more, one word is arranged in overlap 50.The width of overlap 50 can be the first subsidence part 21 width 1/10~
1/5, such as 1/10,1/9,1/8,1/7,1/6 or 1/5 etc..Suppending hole 51 can be round, rectangular etc..The size of suppending hole 51 can
For 0.2~0.5 times of the width of overlap 50, such as 0.2,0.25,0.3,0.35,0.40,0.45 or 0.50.
In yet another embodiment, blood bag 100, are used for the centrifugal sedimentation of blood, including bag body 20, this bag of body 20 includes one
First subsidence part 21, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part 22, for being received after the centrifugal sedimentation
Collect blood platelet, leucocyte；One third subsidence part 23, for collecting red blood cell after the centrifugal sedimentation；Second subsidence part 22
Both ends are respectively communicated with the first subsidence part 21 and third subsidence part 23.The width of first subsidence part 21 is more than the width of the second subsidence part 22
Degree.The width of third subsidence part 23 is more than the width of second subsidence part 22.The width of first subsidence part 21 is more than described the
The width of three subsidence parts 23.First subsidence part 21 is taper.Third subsidence part 23 is elliposoidal.Second subsidence part 22 is vertical bar
Shape.Second subsidence part 22 is communicated with outlet 30 and inlet tube 40.The internal diameter of inlet tube 40 is more than the outlet 30.Bag body 20
It is additionally provided with overlap 50, the overlap 50 offers suppending hole 51.Bag body 20 is additionally provided with for adjusting the first subsidence part 21 and third
The regulating member (not shown) of 23 volume of subsidence part.
In this embodiment, the realization method of regulating member has very much.In the first realization method, regulating member is to practise
The mouth clip known or similar structure, or can refer to such as patent document CN203064381U, specially：Long-tail mouth clip, packet
Binder clip, discharging straight tube, nut and straight tube lid are included, the intermediate plate of the binder clip is metal, and intermediate plate longitudinal section is triangle, described
The clamp holder of binder clip be hingedly connected at intermediate plate up and down dop both sides, intermediate plate up and down dop centre setting indentation tube seat, folder
Circular hole is arranged in the centre of piece tail end facade, can clamp discharging straight tube and packaging bag together, and setting is convex among discharging straight tube
Edge, flange top are screw thread mouth, and lower part is straight mouth.
In second of realization method, regulating member can refer to Chinese patent literature CN 204918610U, specially：It should
Cell culture bags special fixture includes bottom plate, upper clamp plate, elastic cleat and bolt, and the upper surface of the bottom plate has boss,
The both sides of the bottom plate have supporting rod, have with the upper clamp plate thickness corresponding and upper and lower directions on the opposite face of the supporting rod
Sliding slot, there is upper and lower directions and threaded hole corresponding with the bolt, the upper clamp plate to hang down with bottom plate for the top of the supporting rod
Straight arrangement, and its sliding is set in the sliding slot, the both sides of the upper clamp plate have the backstop ear with contact above and below the supporting rod
There is in the backstop ear through-hole corresponding to the threaded hole, the elastic cleat to be fixed on the lower end of the upper clamp plate in portion
The opposite face of face, the elastic cleat and the boss is arc surface that can be tangent with the boss, and the end of thread of the bolt passes through
The through-hole is fixed in the threaded hole.Further include two springs, described two springs are respectively arranged on the upper clamp plate both sides
Backstop ear and the supporting rod of bottom plate both sides between, the end of thread of the bolt passes through the through-hole and spring to be fixed on institute
It states in threaded hole.
Although it is above it is more used the term for indicating structure, such as " bag body 20 ", " the first subsidence part 21 ", " second is heavy
Drop portion 22 ", " third subsidence part 23 " etc., but it does not preclude the possibility of using other terms.The use of these terms is only to be
More easily describe and explain the essence of the present invention；Being construed as any one of the additional limitations all is and present invention essence
What god disagreed.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (10)
1. a kind of blood bag is used for the centrifugal sedimentation of blood, which is characterized in that including bag body, the bag body includes one first sedimentation
Portion, for collecting blood plasma after the centrifugal sedimentation；One second subsidence part, for after the centrifugal sedimentation collect blood platelet,
Leucocyte；One third subsidence part, for collecting red blood cell after the centrifugal sedimentation；The both ends of second subsidence part connect respectively
Lead to first subsidence part and third subsidence part.
2. blood bag according to claim 1, which is characterized in that the width of first subsidence part is more than described second and settles
The width in portion.
3. blood bag according to claim 1, which is characterized in that the width of the third subsidence part is more than described second and settles
The width in portion.
4. blood bag according to claim 1, which is characterized in that the width of first subsidence part is settled more than the third
The width in portion.
5. blood bag according to claim 1, which is characterized in that first subsidence part is taper.
6. blood bag according to claim 1, which is characterized in that the third subsidence part is elliposoidal.
7. blood bag according to claim 1, which is characterized in that second subsidence part is vertical bar shaped.
8. blood bag according to claim 1, which is characterized in that second subsidence part is communicated with outlet and inlet tube.
9. blood bag according to claim 8, which is characterized in that the internal diameter of the inlet tube is more than the outlet.
10. blood bag according to claim 1, which is characterized in that the bag body is additionally provided with overlap, and the overlap offers outstanding
Hanging hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810438434.8A CN108498329A (en) | 2018-05-09 | 2018-05-09 | A kind of blood bag |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810438434.8A CN108498329A (en) | 2018-05-09 | 2018-05-09 | A kind of blood bag |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108498329A true CN108498329A (en) | 2018-09-07 |
Family
ID=63400150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810438434.8A Pending CN108498329A (en) | 2018-05-09 | 2018-05-09 | A kind of blood bag |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108498329A (en) |
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| CN2477185Y (en) * | 2001-05-23 | 2002-02-20 | 朱晓明 | Medical blood taking bag |
| CN1558857A (en) * | 2001-09-28 | 2004-12-29 | ��ʽ����Jms | Clip |
| CN102242054A (en) * | 2011-05-11 | 2011-11-16 | 浙江星月生物科技股份有限公司 | Totally-enclosed cell and cell factor preparation device and preparation method thereof |
| CN103028154A (en) * | 2011-12-14 | 2013-04-10 | 南京双威生物医学科技有限公司 | Platelet separation bag and method for manually separating platelet |
| CN203064381U (en) * | 2013-02-19 | 2013-07-17 | 西安科技大学 | Long tail bag opening clamp |
| CN204918610U (en) * | 2015-09-07 | 2015-12-30 | 上海逍鹏生物科技有限公司 | Cell culture bag special fixture |
| CN106963640A (en) * | 2017-05-02 | 2017-07-21 | 浙江绿蔻生物技术有限公司 | Blood sampling separation bag |
| CN108342357A (en) * | 2018-05-08 | 2018-07-31 | 深圳市祥平元创科技有限公司 | A kind of high-purity leucocyte extracting method and device |
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2018
- 2018-05-09 CN CN201810438434.8A patent/CN108498329A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2194721Y (en) * | 1994-06-21 | 1995-04-19 | 徐州市红十字中心血站 | Link bag for separation of blood white membrane |
| JPH09206356A (en) * | 1996-02-05 | 1997-08-12 | Nissho Corp | Blood bag and blood component separation method |
| CN2477185Y (en) * | 2001-05-23 | 2002-02-20 | 朱晓明 | Medical blood taking bag |
| CN1558857A (en) * | 2001-09-28 | 2004-12-29 | ��ʽ����Jms | Clip |
| CN102242054A (en) * | 2011-05-11 | 2011-11-16 | 浙江星月生物科技股份有限公司 | Totally-enclosed cell and cell factor preparation device and preparation method thereof |
| CN103028154A (en) * | 2011-12-14 | 2013-04-10 | 南京双威生物医学科技有限公司 | Platelet separation bag and method for manually separating platelet |
| CN203064381U (en) * | 2013-02-19 | 2013-07-17 | 西安科技大学 | Long tail bag opening clamp |
| CN204918610U (en) * | 2015-09-07 | 2015-12-30 | 上海逍鹏生物科技有限公司 | Cell culture bag special fixture |
| CN106963640A (en) * | 2017-05-02 | 2017-07-21 | 浙江绿蔻生物技术有限公司 | Blood sampling separation bag |
| CN108342357A (en) * | 2018-05-08 | 2018-07-31 | 深圳市祥平元创科技有限公司 | A kind of high-purity leucocyte extracting method and device |
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