CN108478467A - A kind of toner and preparation method thereof - Google Patents
A kind of toner and preparation method thereof Download PDFInfo
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- CN108478467A CN108478467A CN201810177616.4A CN201810177616A CN108478467A CN 108478467 A CN108478467 A CN 108478467A CN 201810177616 A CN201810177616 A CN 201810177616A CN 108478467 A CN108478467 A CN 108478467A
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- Prior art keywords
- glycerine
- ursin
- toner
- niacinamide
- panthenol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of toners, include the component of following parts by weight：4~6wt% of phosphate buffer, 2~5wt% of dipotassium glycyrrhizinate, 1~3wt% of glycerine, 0.05~0.15wt% of sodium hyaluronate, 0.2~0.6wt% of beta glucan, 0.2~0.8wt% of preservative, 1~3wt% of glycine betaine, 0.2~0.8wt% of acetyl chitosamine, 0.5~1.5wt% of niacinamide, methyl gluceth 20 or methyl gluceth 10 are 1~3wt%, 0.2~0.8wt% of ursin, 0.1~0.5wt% of mannitol, 0.1~0.5wt% of panthenol, and 1~3wt% of glycerine polymethacrylates；Surplus is deionized water.Toner disclosed by the invention, easily prepared, production cost is relatively low, and skin is enabled to have higher activity and moisture retention, also has the multiple efficacies such as sterilization, antibacterial, anti-inflammatory, removing toxic substances, antiallergic, deodorization.
Description
Technical field
The present invention relates to a kind of toner and for the preparation method of the toner.
Background technology
Toner is also referred to as firming lotion, toner etc., and main function, which is that, to be cleaned again to restore the acid of skin surface
Base number, and cuticula is improved, so that skin is preferably absorbed, and prepare for application maintenance product.The main component of toner is water
It is that moisturizer, the maximum effect of firming lotion are careful pore with the height of moisturizer, moisturizing degree, it can be with active balance
Fat secretion is increasingly welcome by modern female.
Chinese patent literature notification number CN106860379A discloses a kind of preparation method of ferment reparation toner, by bee
Glue extracting solution, hazel extract, ursin, puridoxine hydrochloride, beta glucan enzyme, Lactobacillus casei, phytosterol, Monot's benzene
Ancestor, epiphysin, Arnica extracting solution, turmeric extract, ferulic acid, seaweed extracted liquor, Fructus Forsythiae extracting solution, smokes extract solution from aloe
Clothing grass extracting solution, Fructus Schisandrae Chinensis extractive solution, garden burnet extracting solution, cloves extracting solution, vitamin C, sodium hyaluronate, hyaluronic acid powder, poly- paddy
Propylhomoserin powder, reed fragrant plant oil, water-soluble olive oil, oat beta glucan, water-soluble dimension E, glycerine, perfume (or spice), ionized water mixed preparing form.It is this
Toner is limited to the activity of skin and the effect of moisture retention, and its ingredient is mostly plant extracts, and manufacturing cost is relatively low, unfavorable
In large-scale production.
Invention content
In order to overcome the deficiencies of existing technologies, technical problem to be solved by the present invention lies in propose a kind of toner, energy
Enough so that skin has higher activity and moisture retention, and also have sterilization, antibacterial, anti-inflammatory, removing toxic substances, antiallergic, deodorization etc. a variety of
Effect.In addition, this toner is easily prepared, production cost is relatively low.
For this purpose, the present invention uses following technical scheme：
The present invention provides a kind of toners, include the component of following parts by weight：4~6wt% of phosphate buffer, Radix Glycyrrhizae
Sour 2~5wt% of dipotassium, 1~3wt% of glycerine, 0.05~0.15wt% of sodium hyaluronate, 0.2~0.6wt% of beta glucan, preservative
0.2~0.8wt%, 1~3wt% of glycine betaine, 0.2~0.8wt% of acetyl chitosamine, 0.5~1.5wt% of niacinamide, methyl Portugal
Sugar alcohol polyethers -20 or methyl gluceth -10 be 1~3wt%, 0.2~0.8wt% of ursin, mannitol 0.1~
0.5wt%, 0.1~0.5wt% of panthenol and 1~3wt% of glycerine polymethacrylates；Surplus is deionized water.
Phosphate buffer is a common buffer solution for being used for biological study, and phosphate buffer helps to protect
Constant pH value is held, the osmotic pressure and ion concentration of solution are usually close with human body pH (isotonic).Dipotassium glycyrrhizinate be white or
Off-white color fine powder, purity have a special sweet taste up to 98%, it is water-soluble it is good, mouthfeel is pure.Dipotassium glycyrrhizinate has antibacterial, anti-inflammatory, solution
The multiple efficacies such as poison, antiallergic, deodorization.Sodium hyaluronate refers generally to hyaluronic acid, is by D-Glucose aldehydic acid and N-acetyl-glucosamine group
At dissacharide units sodium hyaluronate, have good heat insulation function.Beta glucan is a kind of polysaccharide, is present in certain micro-organisms in life
In the mucus secreted in growth process, there is high bioactivity.Glycine betaine is a kind of alkaloid, has strong hygroscopicity
Can, for the secondary metabolite of metabolism, it is very important osmotic adjustment, people have found have a kind of ingredient that can rise in beet
To fine cleaning action, and skin is not injured, it is very safe, it is named as glycine betaine, modern age be used to clean class skin care item peace
It is complete effective.The product that acetyl chitosamine is obtained by chitosan moiety deacetylation, chitin mostly come from shellfish
Shell, such as shrimp crab play the role of that skin moisturizing ingredients sodium hyaluronate is promoted to generate.Niacinamide is also known as niacinamide, is niacin
Amide compound can prevent pachylosis.Methyl gluceth -20 or methyl gluceth -10 are one kind by natural
The moisturizing ingredient of Derived from D-Glucose, as mild as a dove, non-stimulated.Ursin also known as Arbutin, white acicular crystal or powder.Extraction
It is derived from the leaf of black bearberry, the generation of melanin can be prevented, by the activity of the internal tyrosinase of inhibition to reduce skin-color
Element deposition, dispelling stain and freckle, while also having the effect of sterilization, anti-inflammatory.Mannitol is that the isomer of D-sorbite is easy
It is dissolved in water, is the solid of white clear, there is the sweet taste of similar sucrose.Panthenol is also known as general phthalyl alcohol, and several originals of vitamin, panthenol is to skin
Have the effects that moisturizing, anti-inflammatory, moisturizing and stimulation cell division with hair, therefore it is widely used in cream, lotion and liquor.
Glycerine polymethacrylates is the lubricant that water-soluble clear gel is not done, and transparent, multi-functional moisturizing substrate increases skin
Sense and lubricity improve moisture retention, prepare transparent, colorless product.
In the present invention further technical solution, toner includes the component of following parts by weight：Phosphate buffer 4.5
~5.5wt%, 2.5~4.5wt% of dipotassium glycyrrhizinate, 1.5~2.5wt% of glycerine, 0.08~0.12wt% of sodium hyaluronate, the Portugals β are poly-
0.25~0.55wt% of sugar, 0.25~0.75wt% of preservative, 1.5~2.5wt% of glycine betaine, acetyl chitosamine 0.25~
0.75wt%, 0.55~1.45wt% of niacinamide, 1.5~2.5wt% of methyl gluceth, ursin 0.25~
0.75wt%, 0.15~0.45wt% of mannitol, 0.15~0.45wt% of panthenol and glycerine polymethacrylates 1.5~
2.5wt%；Surplus is deionized water.
In the present invention further technical solution, toner includes phosphate buffer 5wt%, dipotassium glycyrrhizinate
3wt%, glycerine 2wt%, sodium hyaluronate 0.1wt%, beta glucan 0.4wt%, preservative 0.5wt%, glycine betaine 2wt%, acetyl shell
Osamine 0.5wt%, niacinamide 1wt%, methyl gluceth 2wt%, ursin 0.5wt%, mannitol 0.3wt%, panthenol
0.3wt% and glycerine polymethacrylates 1wt%；Surplus is deionized water.
The present invention also provides a kind of preparation methods for above-mentioned toner, implement as follows：First by phosphoric acid
Salt buffer 5wt%, dipotassium glycyrrhizinate 3wt%, glycerine 2wt%, sodium hyaluronate 0.1wt%, mannitol 0.3wt%, panthenol
0.3wt% is added into suitable deionized water solution, and by blender to be stirred with 1500-2000r/min mixing speeds
Appropriate time is controlled mixeding liquid temperature at 85~90 DEG C by mode of heating；Then, it stands and waits for that temperature is down to 60 DEG C or so
When, beta glucan 0.4wt%, preservative 0.5wt%, glycine betaine 2wt%, acetyl chitosamine 0.5wt%, niacinamide is added
1wt%, methyl gluceth 2wt%, ursin 0.5wt% and glycerine polymethacrylates 1wt%, continue through and stir
Device is mixed to stir appropriate time with 500-2000r/min mixing speeds, until temperature drops to 40 DEG C or so.Finally, it stands extremely
It is sealed after room temperature.
Beneficial effects of the present invention are：
Toner provided by the invention, including the substances such as phosphate buffer, sodium hyaluronate and beta glucan so that skin toner
Water has higher activity and moisture retention.Toner, which further includes ursin, can effectively reduce Skin pigmentation, dispelling stain
And freckle, the combination of ursin and dipotassium glycyrrhizinate make toner have sterilization, antibacterial, anti-inflammatory, removing toxic substances, antiallergic, deodorization etc.
Multiple efficacies.It can be seen that toner provided by the invention is a kind of comprehensive skin care item with multiple skin-protecting function.
Specific implementation mode
The technical solution further illustrated the present invention below by specific implementation mode.
Embodiment one
The toner provided in the present embodiment includes the component of following parts by weight：Phosphate buffer 4wt%, glycyrrhizic acid
Dipotassium 2wt%, glycerine 1wt%, sodium hyaluronate 0.05wt%, beta glucan 0.2wt%, preservative 0.2wt%, glycine betaine 1wt%,
Acetyl chitosamine 0.2wt%, niacinamide 0.5wt%, methyl gluceth 1wt%, ursin 0.2wt%, mannitol
0.1wt%, panthenol 0.1wt% and glycerine polymethacrylates 1wt%；Surplus is deionized water.It is provided by the invention refreshing
Skin water has multiple skin-protecting function.
Embodiment two
The toner provided in the present embodiment includes the component of following parts by weight：Phosphate buffer 6wt%, glycyrrhizic acid
Dipotassium 5wt%, glycerine 3wt%, sodium hyaluronate 0.15wt%, beta glucan 0.6wt%, preservative 0.8wt%, glycine betaine 3wt%,
Acetyl chitosamine 0.8wt%, niacinamide 1.5wt%, methyl gluceth 3wt%, ursin 0.8wt%, mannitol
0.5wt%, panthenol 0.5wt% and glycerine polymethacrylates 3wt%；Surplus is deionized water.
Embodiment three
The toner provided in the present embodiment includes the component of following parts by weight：Phosphate buffer 4.5wt%, Radix Glycyrrhizae
Sour dipotassium 2.5wt%, glycerine 1.5wt%, sodium hyaluronate 0.08wt%, beta glucan 0.25wt%, preservative 0.25wt%, beet
Alkali 1.5wt%, acetyl chitosamine 0.25wt%, niacinamide 0.55wt%, methyl gluceth 1.5wt%, ursin
0.25wt%, mannitol 0.15wt%, panthenol 0.15wt% and glycerine polymethacrylates 1.5wt%；Surplus be go from
Sub- water.
Example IV
The toner provided in the present embodiment includes the component of following parts by weight：Phosphate buffer 5.5wt%, Radix Glycyrrhizae
Sour dipotassium 4.5wt%, glycerine 2.5wt%, sodium hyaluronate 0.12wt%, beta glucan 0.55wt%, preservative 0.75wt%, beet
Alkali 2.5wt%, acetyl chitosamine 0.75wt%, niacinamide 1.45wt%, methyl gluceth 2.5wt%, ursin
0.75wt%, mannitol 0.45wt%, panthenol 0.45wt% and glycerine polymethacrylates 2.5wt%；Surplus be go from
Sub- water.
Embodiment five
The toner provided in the present embodiment includes the component of following parts by weight：Phosphate buffer 5wt%, glycyrrhizic acid
Dipotassium 3wt%, glycerine 2wt%, sodium hyaluronate 0.1wt%, beta glucan 0.4wt%, preservative 0.5wt%, glycine betaine 2wt%, second
Acyl chitosamine 0.5wt%, niacinamide 1wt%, methyl gluceth 2wt%, ursin 0.5wt%, mannitol 0.3wt%,
Panthenol 0.3wt% and glycerine polymethacrylates 1wt%；Surplus is deionized water.Phosphate buffer is commonly to use
In a buffer solution of biological study, phosphate buffer helps to maintain constant pH value, the osmotic pressure of solution and from
Sub- concentration is usually close with human body pH (isotonic).Dipotassium glycyrrhizinate is white or off-white color fine powder, purity has spy up to 98%
Different sweet taste, it is water-soluble it is good, mouthfeel is pure.Dipotassium glycyrrhizinate has the multiple efficacies such as antibacterial, anti-inflammatory, removing toxic substances, antiallergic, deodorization.Sodium hyaluronate
Refer generally to hyaluronic acid, the dissacharide units sodium hyaluronate being made of D-Glucose aldehydic acid and N-acetyl-glucosamine has good
Heat insulation function.Beta glucan is a kind of polysaccharide, is present in the mucus that certain micro-organisms is secreted in growth course, is had high
Bioactivity.Glycine betaine is a kind of alkaloid, and it for the secondary metabolite of metabolism is extremely important to have strong moisture pick-up properties
Osmotic adjustment, people have found have a kind of ingredient that can play fine cleaning action in beet, and do not injure skin, non-
Chang Anquan is named as glycine betaine, and modern age be used to clean class skin care item safe and effective.Acetyl chitosamine is taken off by chitosan moiety
The product that acetyl group obtains, chitin mostly come from the shell of shellfish, such as shrimp crab, there is promotion skin moisturizing ingredients
The effect that sodium hyaluronate generates.Niacinamide is also known as niacinamide, is the amide compound of niacin, can prevent pachylosis.Methyl
Glucitol polyethers -20 or methyl gluceth -10 are a kind of moisturizing ingredients derived from natural glucose, as mild as a dove, nothing
Stimulation.Ursin also known as Arbutin, white acicular crystal or powder.The leaf from black bearberry is extracted, it can be by inhibiting internal
The activity of tyrosinase prevents the generation of melanin, to reduce Skin pigmentation, dispelling stain and freckle, also has simultaneously
It sterilizes, the effect of anti-inflammatory.Mannitol is that the isomer of D-sorbite is soluble easily in water, is the solid of white clear, has similar
The sweet taste of sucrose.Panthenol is also known as general phthalyl alcohol, several originals of vitamin, and panthenol has moisturizing, anti-inflammatory, moisturizing and thorn to skin and hair
The effects that swashing cell division, therefore it is widely used in cream, lotion and liquor.Glycerine polymethacrylates is water-soluble transparent
The lubricant that gel is not done, transparent, multi-functional moisturizing substrate increase skin sense and lubricity, improve moisture retention, prepare saturating
It is bright, colorless product.In conclusion toner provided by the invention, can either make skin have higher activity and moisture retention,
Skin pigmentation, dispelling stain and freckle can be effectively reduced again, and also there is sterilization, antibacterial, anti-inflammatory, removing toxic substances, antiallergic, remove
The multiple efficacies such as smelly are a kind of comprehensive skin protection cosmetics with a variety of U.S. face skin-protecting functions.
Embodiment six
A kind of preparation method for above-mentioned toner is provided in the present embodiment, is implemented as follows：First by phosphorus
Phthalate buffer 5wt%, dipotassium glycyrrhizinate 3wt%, glycerine 2wt%, sodium hyaluronate 0.1wt%, mannitol 0.3wt%, panthenol
0.3wt% is added into suitable deionized water solution, and by blender to be stirred with 1500-2000r/min mixing speeds
Appropriate time is controlled mixeding liquid temperature at 85~90 DEG C by mode of heating；Then, it stands and waits for that temperature is down to 60 DEG C or so
When, beta glucan 0.4wt%, preservative 0.5wt%, glycine betaine 2wt%, acetyl chitosamine 0.5wt%, niacinamide is added
1wt%, methyl gluceth 2wt%, ursin 0.5wt% and glycerine polymethacrylates 1wt%, continue through and stir
Device is mixed to stir appropriate time with 500-2000r/min mixing speeds, until temperature drops to 40 DEG C or so.Finally, it stands extremely
It is sealed after room temperature.
The present invention is described with reference to the preferred embodiments, and those skilled in the art know, is not departing from the present invention's
In the case of spirit and scope, various changes or equivalence replacement can be carried out to these features and embodiment.The present invention is not by this
The limitation of specific embodiment disclosed in place, other embodiments fallen into claims hereof belong to protection of the present invention
Range.
Claims (4)
1. a kind of toner, which is characterized in that include the component of following parts by weight：4~6wt% of phosphate buffer, glycyrrhizic acid
2~5wt% of dipotassium, 1~3wt% of glycerine, 0.05~0.15wt% of sodium hyaluronate, 0.2~0.6wt% of beta glucan, preservative 0.2
~0.8wt%, 1~3wt% of glycine betaine, 0.2~0.8wt% of acetyl chitosamine, 0.5~1.5wt% of niacinamide, methyl alcohol
1~3wt% of polyethers, 0.2~0.8wt% of ursin, 0.1~0.5wt% of mannitol, 0.1~0.5wt% of panthenol and glycerine
1~3wt% of polymethacrylates；Surplus is deionized water.
2. toner according to claim 1, it is characterised in that：
Include the component of following parts by weight：4.5~5.5wt% of phosphate buffer, 2.5~4.5wt% of dipotassium glycyrrhizinate, glycerine
1.5~2.5wt%, 0.08~0.12wt% of sodium hyaluronate, 0.25~0.55wt% of beta glucan, 0.25~0.75wt% of preservative,
1.5~2.5wt% of glycine betaine, 0.25~0.75wt% of acetyl chitosamine, 0.55~1.45wt% of niacinamide, methyl alcohol are poly-
1.5~2.5wt% of ether, 0.25~0.75wt% of ursin, 0.15~0.45wt% of mannitol, 0.15~0.45wt% of panthenol,
And 1.5~2.5wt% of glycerine polymethacrylates；Surplus is deionized water.
3. toner according to claim 2, it is characterised in that：
Phosphate buffer 5wt%, dipotassium glycyrrhizinate 3wt%, glycerine 2wt%, sodium hyaluronate 0.1wt%, beta glucan 0.4wt%,
Preservative 0.5wt%, glycine betaine 2wt%, acetyl chitosamine 0.5wt%, niacinamide 1wt%, methyl gluceth 2wt%,
Ursin 0.5wt%, mannitol 0.3wt%, panthenol 0.3wt% and glycerine polymethacrylates 1wt%；Surplus is to go
Ionized water.
4. a kind of preparation method for claims 1 to 3 any one of them toner, it is characterised in that：First by phosphate
Buffer solution 5wt%, dipotassium glycyrrhizinate 3wt%, glycerine 2wt%, sodium hyaluronate 0.1wt%, mannitol 0.3wt%, panthenol 0.3wt%
It is added in suitable deionized water solution, and when by blender to stir appropriate with 1500-2000r/min mixing speeds
Between, mixeding liquid temperature is controlled at 85~90 DEG C by mode of heating；Then, it stands when temperature is down to 60 DEG C or so, β is added
Glucan 0.4wt%, preservative 0.5wt%, glycine betaine 2wt%, acetyl chitosamine 0.5wt%, niacinamide 1wt%, methyl Portugal
Sugar alcohol polyethers 2wt%, ursin 0.5wt% and glycerine polymethacrylates 1wt%, continue through blender with 500-
2000r/min mixing speeds stir appropriate time, until temperature drops to 40 DEG C or so.Finally, it is sealed after standing to room temperature.
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2018
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| WO2000038646A1 (en) * | 1998-12-23 | 2000-07-06 | The Boots Company Plc | Dermatological compositions containing tannic acid and a microbial proliferation inhibitor |
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| CN106309237A (en) * | 2016-09-26 | 2017-01-11 | 杭州惠博士生物科技有限公司 | Hyaluronic acid private part care gel and preparation method thereof |
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