CN108477598A - Polysaccharide lucidum spore powder compounding tablet based on edible mushroom by-product and preparation process - Google Patents
Polysaccharide lucidum spore powder compounding tablet based on edible mushroom by-product and preparation process Download PDFInfo
- Publication number
- CN108477598A CN108477598A CN201810219780.7A CN201810219780A CN108477598A CN 108477598 A CN108477598 A CN 108477598A CN 201810219780 A CN201810219780 A CN 201810219780A CN 108477598 A CN108477598 A CN 108477598A
- Authority
- CN
- China
- Prior art keywords
- powder
- polysaccharide
- edible mushroom
- ultramicro
- lucidum spore
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000843 powder Substances 0.000 title claims abstract description 82
- 150000004676 glycans Chemical class 0.000 title claims abstract description 56
- 229920001282 polysaccharide Polymers 0.000 title claims abstract description 56
- 239000005017 polysaccharide Substances 0.000 title claims abstract description 56
- 235000001674 Agaricus brunnescens Nutrition 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title claims abstract description 27
- 239000006227 byproduct Substances 0.000 title claims abstract description 19
- 238000013329 compounding Methods 0.000 title claims abstract description 17
- 241000233866 Fungi Species 0.000 claims abstract description 20
- 241000222336 Ganoderma Species 0.000 claims abstract description 19
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims abstract description 17
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims abstract description 17
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims abstract description 17
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims abstract description 17
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 12
- 238000001556 precipitation Methods 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 238000001035 drying Methods 0.000 claims abstract description 8
- 238000002156 mixing Methods 0.000 claims abstract description 8
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 238000009835 boiling Methods 0.000 claims abstract description 7
- 238000000227 grinding Methods 0.000 claims abstract description 7
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 6
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 6
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 6
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 6
- 238000012216 screening Methods 0.000 claims abstract description 6
- 239000006228 supernatant Substances 0.000 claims abstract description 6
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims abstract description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 5
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims abstract description 5
- 239000012535 impurity Substances 0.000 claims abstract description 5
- 239000000853 adhesive Substances 0.000 claims abstract description 4
- 230000001070 adhesive effect Effects 0.000 claims abstract description 4
- 238000004140 cleaning Methods 0.000 claims abstract description 4
- 239000012530 fluid Substances 0.000 claims abstract description 3
- 238000002386 leaching Methods 0.000 claims abstract description 3
- 240000008397 Ganoderma lucidum Species 0.000 claims description 25
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims description 24
- 150000001875 compounds Chemical class 0.000 claims description 5
- 238000005469 granulation Methods 0.000 claims description 5
- 230000003179 granulation Effects 0.000 claims description 5
- 244000252132 Pleurotus eryngii Species 0.000 claims description 3
- 235000001681 Pleurotus eryngii Nutrition 0.000 claims description 3
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims 1
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 239000000047 product Substances 0.000 description 12
- 238000009700 powder processing Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 229930006000 Sucrose Natural products 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 239000000470 constituent Substances 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 235000016709 nutrition Nutrition 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 229960004793 sucrose Drugs 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 108010006464 Hemolysin Proteins Proteins 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000003228 hemolysin Substances 0.000 description 2
- -1 hydroxypropyl methyl Chemical group 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 241001264174 Cordyceps militaris Species 0.000 description 1
- 102000004889 Interleukin-6 Human genes 0.000 description 1
- 108090001005 Interleukin-6 Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 229920003091 Methocel™ Polymers 0.000 description 1
- 240000001307 Myosotis scorpioides Species 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 235000004251 balanced diet Nutrition 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000000035 biogenic effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000007888 film coating Substances 0.000 description 1
- 238000009501 film coating Methods 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 229940100601 interleukin-6 Drugs 0.000 description 1
- 230000007413 intestinal health Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000005229 liver cell Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 238000005502 peroxidation Methods 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000005550 wet granulation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses polysaccharide lucidum spore powder compounding tablets and preparation process based on edible mushroom by-product, and edible mushroom by-product is through removal of impurities, cleaning, drying, the air blast drying in baking oven, ultramicro grinding, and edible mushroom Ultramicro-powder is made in screening;Edible mushroom Ultramicro-powder is weighed, ultrasonic-leaching centrifuges, and after supernatant concentration, absolute ethyl alcohol is added, centrifuging and taking precipitation, after precipitation is vacuum dried, edible fungi polysaccharide Ultramicro-powder is made in ultramicro grinding;Lucidum spore powder cleans, broken wall, and ganoderma spove powder is made;By ganoderma spove powder, edible fungi polysaccharide Ultramicro-powder, maltodextrin, oligofructose, antierythrite, compounding powder is made in calcium carbonate.In addition, hydroxypropyl methyl cellulose is individually placed, it is spare;First suck the raw material mixing in addition to hydroxypropyl methyl cellulose;Water is added in hydroxypropyl methyl cellulose to mix, as adhesive;Pass through fluid bed boiling granulating.The beneficial effects of the invention are as follows being easily achieved, can be continuously produced, it is suitble to industrial applications.
Description
Technical field
The invention belongs to technical field of functional food, are related to a kind of polysaccharide/Reishi sporule from edible mushroom by-product
Powder compounds tablet and its preparation process.
Background technology
Edible mushroom is the fifth-largest industry after agricultural industry relaying grain, vegetables, fruit tree, oil plant.Edible mushroom is not only sought
It is foster abundant, and containing various bioactivators such as polysaccharide, protein, flavones and sequiterpenes, have and maintain intestinal health, resist
The functional characteristics such as oxidation.Edible mushroom consumes by numerous, region is wide, it has also become the important component of ordinary meal.The United Nations's grain
The balanced diet structure of agriculture Organisation recommendations " meat or fish one plain a mushroom ", edible fungi polysaccharide be in edible mushroom most important bioactivity at
Point.The edible fungi polysaccharide of science extraction is simultaneously compounded with other functional components, prepares the nutrition of nutrient balance and functional activity complementation
Health food is of great significance for promoting the general level of the health, efficiently using nutrition composition.Ganoderma lucidum Ganoderma lucidum
(Curtis:Fr.) P.Karst. is the rare medicinal fungi in China.Since it has abundant nutritional ingredient and physiological activity work(
Can, it can prevent or treat numerous diseases, once be referred to as in ancient times " celestial grass ".In recent years, the country in Southeast Asia including China
And many scholars of America & Canada have made intensive studies ganoderma lucidum.Modern scientific research proves, there are many ganoderma lucidum contains
Bioactive ingredients, such as polysaccharide, triterpene, sterol, nucleic acid, protein, polypeptide, aliphatic acid, wherein ganoderma lucidum polysaccharide and ganoderma lucidum three
Terpene is the key function ingredient of ganoderma lucidum.Modern science shows that ganoderma lucidum polysaccharide has and removes interior free yl, improves SOD activity, drop
Low liver cell LPO, anti-lipid peroxidation, enhancing antioxidant ability of organism and the effect for improving immunity.On the other hand, I
State largely natural Plant And Animal Resources In Naturalreserve and long-time clinical practice and the Chinese Traditional Medicine prescription under accumulating also be modern health,
The research for the treatment of disease scheduling theory provides abundant experimental material.Wherein, for ganoderma lucidum as precious edible and medical fungi, ganoderma lucidum is related
Production technology has become the hot spot that domestic and foreign scholars competitively develop, study.But the preparation process of traditional ganoderma lucidum polysaccharide piece
The middle auxiliary material used is more, 20% or more general sucrose addition, and ganoderma lucidum component content only 50% or so, and there are active ingredients
The problems such as content is low, and taking dose is big, and diabetic cannot be eaten.
Invention content
The purpose of the present invention is to provide polysaccharide lucidum spore powder compounding tablets and preparation work based on edible mushroom by-product
Skill, solves in the preparation process of traditional ganoderma lucidum polysaccharide piece that, cane sugar content more using auxiliary material is high, active constituent content is low, takes
The problem of dosage is big, diabetic inedibility.The beneficial effects of the invention are as follows being easily achieved, can be continuously produced, it is suitble to
Industrial applications.
The technical solution adopted in the present invention is to follow the steps below:
(1) preparation of edible mushroom Ultramicro-powder:Edible mushroom by-product is through removal of impurities, cleaning, drying, the air blast drying in baking oven,
Edible mushroom Ultramicro-powder is made in ultramicro grinding, screening;
(2) preparation of edible fungi polysaccharide:Edible mushroom Ultramicro-powder is weighed, ultrasonic-leaching centrifuges, and after supernatant concentration, adds
Enter absolute ethyl alcohol, centrifuging and taking precipitation, after precipitation is vacuum dried, edible fungi polysaccharide Ultramicro-powder is made in ultramicro grinding;
(3) preparation of lucidum spore powder:Lucidum spore powder cleans, broken wall, and ganoderma spove powder is made;
(4) raw material compounds:By ganoderma spove powder, edible fungi polysaccharide Ultramicro-powder, maltodextrin, oligofructose, red moss
Compounding powder is made in sugar alcohol, calcium carbonate.In addition, hydroxypropyl methyl cellulose is individually placed, it is spare;
(5) granulation and tabletting:First suck the raw material mixing in addition to hydroxypropyl methyl cellulose;By hydroxypropyl methyl fiber
Water mixing is added in element, as adhesive;Pass through fluid bed boiling granulating.
Further, in step (1) edible mushroom by-product according to needle mushroom:30wt%, Pleurotus eryngii:30wt%, ganoderma lucidum:
The ratio of 40wt%.
Further, edible mushroom Ultramicro-powder adds 12mL water per 1g in step (2).
Further, in step (2) edible fungi polysaccharide preparation condition:Ultrasonic power 750W, 80 DEG C of temperature extract 30 points
Clock, 5000rpm are centrifuged, and after supernatant concentration, the absolute ethyl alcohol of 4 times of volumes, 3500rpm centrifuging and takings precipitation is added.
Further, lucidum spore powder cleans in step (3), and moisture is controlled less than 6%.
Further, ganoderma spove powder 52% in step (4), edible fungi polysaccharide Ultramicro-powder 15%, maltodextrin 17%,
Oligofructose 4%, antierythrite 3%, calcium carbonate 6%, hydroxypropyl methyl cellulose 3%
Further, hydroxypropyl methyl cellulose is added 1 in step (5):1 water mixing.
Further, fluidized-bed temperature is at 48 DEG C in step (5), atomizing pressure >=0.18MPa.
Description of the drawings
Fig. 1 is lucid ganoderma spore powder polysaccharide boiling/spraying granulation particle;
Fig. 2 is lucid ganoderma spore powder polysaccharide coating tablets product;
Fig. 3 is lucid ganoderma spore powder polysaccharide piece not coated product.
Specific implementation mode
The present invention is described in detail With reference to embodiment.
Embodiment 1
1. the preparation of edible mushroom Ultramicro-powder:Fresh food bacterium by-product is through removal of impurities, cleaning, drying, 55 DEG C of drums in baking oven
Wind is dried, needle mushroom:30wt%, Pleurotus eryngii:30wt%, ganoderma lucidum:The ratio ultramicro grinding of 40wt%, 300 mesh screening, is made food
With bacterium Ultramicro-powder;
2. the preparation of edible fungi polysaccharide:Edible mushroom Ultramicro-powder is weighed, adds 12mL water, ultrasonic power by every 1g Ultramicro-powders
750W, 80 DEG C of temperature extract 30 minutes, 5000rpm centrifugations, and after supernatant concentration, the absolute ethyl alcohol of 4 times of volumes is added,
3500rpm centrifuging and takings precipitate, and after precipitation is vacuum dried, edible fungi polysaccharide Ultramicro-powder is made in ultramicro grinding, 300 mesh screening;
3. the preparation of lucidum spore powder:Fresh glossy ganoderma conidia powder raw material screening, removal impurity, part of going mouldy, then carries out
It cleans, 55 DEG C of air blast drying in baking oven, moisture control carries out broken wall using ultralow temperature physical wall breaking equipment, be made less than 6%
Ganoderma spove powder.
4. raw material compounds:By the edible fungi polysaccharide powder and lucidum spore powder that are obtained in step (2) and step (3) according to ganoderma lucidum
Conidia powder 52%%, edible fungi polysaccharide 15%, maltodextrin 17%, oligofructose 4%, antierythrite 3%, calcium carbonate 6%, than
Uniformly compounding powder is made in example.In addition, hydroxypropyl methyl cellulose (HPMC) 3% is individually placed, it is spare
5. granulation and tabletting:First raw material of the sucking in addition to hydroxypropyl methyl cellulose (HPMC) mixes 15 minutes;By hydroxyl
Propyl methocel (HPMC) is added 1:1 water mixing, as adhesive;Fluidized-bed temperature is controlled at 48 DEG C, atomizing pressure
The state of >=0.18MPa, boiling granulating;It is 54kgf plain pieces, film packet that particle obtained, which enters high speed tablet press to extrude hardness,
Clothing, packaging obtain finished product lucid ganoderma spore powder polysaccharide piece.
Embodiment 2
The present embodiment lucid ganoderma spore powder polysaccharide piece preparation method is identical as the step in embodiment 1, difference lies in without
Film coating.
As shown in Figure 1, being lucid ganoderma spore powder polysaccharide boiling/spraying granulation particle;Fig. 2 is lucid ganoderma spore powder polysaccharide coating tablets
Product;Fig. 3 is lucid ganoderma spore powder polysaccharide piece not coated product.Tablet powder is compounded using polysaccharide/lucidum spore powder of the present invention
Zoopery is carried out with the ganoderma lucidum polysaccharide tablet powder of traditional handicraft.3 groups of zoopery point, control group, polysaccharide of the invention/
Lucidum spore powder compounds tablet powder processing group, the ganoderma lucidum polysaccharide tablet powder processing group of traditional handicraft, every group of 20 mouse.It is right
According to group normal basal feed of feeding, test group feeds the lucid ganoderma spore powder polysaccharide piece powder of identical weight, and feeding is distinguished after 30 days
Measure poor mouse ear sheet weight, phagocytic index, the antibody product of serum hemolysin, thymus gland/weight, spleen/weight, liver/body
7 indexs such as interleukin-6 content in weight and liver.Test result such as table 1, by data in table 1 it is found that edible spore containing ganoderma lucidum
Sub- powder polysaccharide tablet powder Feed Energy significantly improves to be situated between in vain in the antibody product and liver of the auricle weight difference of mouse, serum hemolysin
Plain -6 contents, also, the significant effect of the polysaccharide of the present invention/lucidum spore powder compounding tablet powder processing group is higher than traditional handicraft
Ganoderma lucidum polysaccharide tablet powder processing group, this show the feed containing Cordyceps militaris superfine powder of the invention to mouse cell immune, body
Liquid is immune apparent humidification, also further demonstrates product active constituent content height of the present invention, same dose intake
Becoming apparent from improves body's immunity.
The variation of mouse immune index after 1 different disposal of table
Note:Data are mean+SD in table;There are significance differences in 0.05 level for same column difference lowercase letter
Different (n=20), test group 1 indicate the ganoderma lucidum polysaccharide tablet powder processing group of traditional handicraft;Test group 2 indicates the spirit of the present invention
Ganoderma lucidum spore powder polysaccharide tablet powder processing group.
Advantage of the present invention also resides in compared with traditional tablet making technology, and the present invention does not use sucrose, ganoderma lucidum component content 55%
More than, product safety is nontoxic, active constituent content is high.Since the product is multiple using multiple eating granulose and lucidum spore powder
Match, bioactivity is complementary, nutrient balance, have than the ingredients Biogenic active higher of single source, more comprehensively advantage, overcome
The weak and single present situation of the activity of some health products currently on the market.The present invention prepares ganoderma lucidum spore using a step boiling granulating technology
Sub- powder polysaccharide tablet compares high speed wet-granulation technique, improves product yield, reduce tablet breakage, reduces auxiliary material use
Amount, improves functional component content, has stronger operability and application value.
The above is only the better embodiment to the present invention, not makees limit in any form to the present invention
System, every any simple modification that embodiment of above is made according to the technical essence of the invention, equivalent variations and modification,
Belong in the range of technical solution of the present invention.
Claims (8)
1. the polysaccharide lucidum spore powder compounding tablet based on edible mushroom by-product and preparation process, it is characterised in that according to following step
It is rapid to carry out:
(1) preparation of edible mushroom Ultramicro-powder:Edible mushroom by-product is through removal of impurities, cleaning, drying, air blast drying, ultra micro in baking oven
It crushes, edible mushroom Ultramicro-powder is made in screening;
(2) preparation of edible fungi polysaccharide:Edible mushroom Ultramicro-powder is weighed, ultrasonic-leaching centrifuges, and after supernatant concentration, nothing is added
Water-ethanol, centrifuging and taking precipitation, after precipitation is vacuum dried, edible fungi polysaccharide Ultramicro-powder is made in ultramicro grinding;
(3) preparation of lucidum spore powder:Lucidum spore powder cleans, broken wall, and ganoderma spove powder is made;
(4) raw material compounds:By ganoderma spove powder, edible fungi polysaccharide Ultramicro-powder, maltodextrin, oligofructose, antierythrite,
Compounding powder is made in calcium carbonate.In addition, hydroxypropyl methyl cellulose is individually placed, it is spare;
(5) granulation and tabletting:First suck the raw material mixing in addition to hydroxypropyl methyl cellulose;By hydroxypropyl methyl cellulose plus
Enter water mixing, as adhesive;Pass through fluid bed boiling granulating.
2. according to polysaccharide lucidum spore powder compounding tablet and preparation process based on edible mushroom by-product described in claim 1,
It is characterized in that:Edible mushroom by-product is according to needle mushroom in the step (1):30wt%, Pleurotus eryngii:30wt%, ganoderma lucidum:40wt%
Ratio.
3. according to polysaccharide lucidum spore powder compounding tablet and preparation process based on edible mushroom by-product described in claim 1,
It is characterized in that:Edible mushroom Ultramicro-powder adds 12mL water per 1g in the step (2).
4. according to polysaccharide lucidum spore powder compounding tablet and preparation process based on edible mushroom by-product described in claim 1,
It is characterized in that:The preparation condition of edible fungi polysaccharide in the step (2):Ultrasonic power 750W, 80 DEG C of temperature extract 30 points
Clock, 5000rpm are centrifuged, and after supernatant concentration, the absolute ethyl alcohol of 4 times of volumes, 3500rpm centrifuging and takings precipitation is added.
5. according to polysaccharide lucidum spore powder compounding tablet and preparation process based on edible mushroom by-product described in claim 1,
It is characterized in that:Lucidum spore powder cleans in the step (3), and moisture is controlled less than 6%.
6. according to polysaccharide lucidum spore powder compounding tablet and preparation process based on edible mushroom by-product described in claim 1,
It is characterized in that:Ganoderma spove powder 52% in the step (4), edible fungi polysaccharide Ultramicro-powder 15%, maltodextrin 17% are low
Fructooligosaccharides 4%, antierythrite 3%, calcium carbonate 6%, hydroxypropyl methyl cellulose 3%.
7. according to polysaccharide lucidum spore powder compounding tablet and preparation process based on edible mushroom by-product described in claim 1,
It is characterized in that:Hydroxypropyl methyl cellulose is added 1 in the step (5):1 water mixing.
8. according to polysaccharide lucidum spore powder compounding tablet and preparation process based on edible mushroom by-product described in claim 1,
It is characterized in that:Fluidized-bed temperature is at 48 DEG C in the step (5), atomizing pressure >=0.18MPa.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810219780.7A CN108477598A (en) | 2018-03-16 | 2018-03-16 | Polysaccharide lucidum spore powder compounding tablet based on edible mushroom by-product and preparation process |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810219780.7A CN108477598A (en) | 2018-03-16 | 2018-03-16 | Polysaccharide lucidum spore powder compounding tablet based on edible mushroom by-product and preparation process |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108477598A true CN108477598A (en) | 2018-09-04 |
Family
ID=63339568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810219780.7A Pending CN108477598A (en) | 2018-03-16 | 2018-03-16 | Polysaccharide lucidum spore powder compounding tablet based on edible mushroom by-product and preparation process |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108477598A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109198640A (en) * | 2018-10-16 | 2019-01-15 | 徐州工程学院 | One bulb spore health-care food contg. Chinese caterpillar fungus and preparation method thereof |
CN113017081A (en) * | 2021-03-11 | 2021-06-25 | 重庆市生物技术研究所有限责任公司 | Ganoderma lucidum spore powder tablet and preparation method thereof |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1765374A (en) * | 2005-10-14 | 2006-05-03 | 陈沙 | Preparation method of ganoderma lucidum chewable tablet and product |
CN103461962A (en) * | 2012-06-07 | 2013-12-25 | 宁波海逸生物科技有限公司 | Formula of sporoderm-broken Ganoderma spore capsule for strengthening immune function |
CN103463458A (en) * | 2013-09-26 | 2013-12-25 | 张娥珍 | Dendrobium candidum compound chewable tablets and preparation method thereof |
CN106511403A (en) * | 2017-01-09 | 2017-03-22 | 仙芝科技(福建)股份有限公司 | Lucid ganoderma tablet and preparation method thereof |
CN107647251A (en) * | 2017-08-24 | 2018-02-02 | 太和县三九药业有限公司 | A kind of preparation method of compound edible mushroom nutrient chewable tablet |
-
2018
- 2018-03-16 CN CN201810219780.7A patent/CN108477598A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1765374A (en) * | 2005-10-14 | 2006-05-03 | 陈沙 | Preparation method of ganoderma lucidum chewable tablet and product |
CN103461962A (en) * | 2012-06-07 | 2013-12-25 | 宁波海逸生物科技有限公司 | Formula of sporoderm-broken Ganoderma spore capsule for strengthening immune function |
CN103463458A (en) * | 2013-09-26 | 2013-12-25 | 张娥珍 | Dendrobium candidum compound chewable tablets and preparation method thereof |
CN106511403A (en) * | 2017-01-09 | 2017-03-22 | 仙芝科技(福建)股份有限公司 | Lucid ganoderma tablet and preparation method thereof |
CN107647251A (en) * | 2017-08-24 | 2018-02-02 | 太和县三九药业有限公司 | A kind of preparation method of compound edible mushroom nutrient chewable tablet |
Non-Patent Citations (1)
Title |
---|
严奉伟等: "《食用菌深加工技术与工艺配方》", 31 May 2002, 科学技术文献出版社 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109198640A (en) * | 2018-10-16 | 2019-01-15 | 徐州工程学院 | One bulb spore health-care food contg. Chinese caterpillar fungus and preparation method thereof |
CN109198640B (en) * | 2018-10-16 | 2020-03-17 | 徐州工程学院 | Cordyceps militaris health food and preparation method thereof |
CN113017081A (en) * | 2021-03-11 | 2021-06-25 | 重庆市生物技术研究所有限责任公司 | Ganoderma lucidum spore powder tablet and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN100407947C (en) | Method for producing health-care food poured with boiling before eating it | |
Zhou et al. | Applied modern biotechnology for cultivation of Ganoderma and development of their products | |
CN101760478B (en) | Preparation method of radix puerariae red yeast rice | |
CN105641000A (en) | Antitumor composition containing grifola frondosus extract and preparation method thereof | |
CN106072491B (en) | A kind of fructus arctii base Ganoderma lucidum mycelium powder and preparation method thereof | |
CN105996022A (en) | Method for producing functional foods by simultaneously converting Chinese yam from cordyceps taishanensis | |
CN109393494A (en) | A kind of person in middle and old age's health-care food composition and its application | |
CN107183688B (en) | A kind of plant composite enzyme and preparation method thereof | |
CN104256286B (en) | Nutritious food with function of boosting immunity and preparation method of nutritious food | |
CN102994305A (en) | Method for preparing health-care food (therapy) product (nutrient juice wine) by use of extracts from cordyceps militaris and cocoon | |
CN108902628A (en) | A kind of anti-inflammatory probiotics solid beverage of children | |
CN108477598A (en) | Polysaccharide lucidum spore powder compounding tablet based on edible mushroom by-product and preparation process | |
CN101176521B (en) | North cordyceps rice flour product and preparation method thereof | |
CN106174475B (en) | A kind of selenoprotein holoside nutrient composite powder and preparation method thereof | |
CN105494843A (en) | Preparation method of blueberry tabletting sweets | |
CN1864530A (en) | A refined health food of high and cold mountain area crop and processing technology thereof | |
CN1461606A (en) | Health-care fruit and vegetable food with function of looseing bowel to relieve constipation and its prodn. method | |
CN101664180A (en) | Health-care nutritional complexing agent with effect of and preparation method thereof | |
CN108618128A (en) | Adjust the composition and its preparation method and application of immunity | |
CN105595351A (en) | Nutritional product with steady blood sugar regulation function, preparation method and application thereof | |
CN103805669A (en) | Preparation method of macromolecular yak skin collagen capable of improving glycogen reserve of organisms | |
JPH10287584A (en) | Physiologically active substance and its production | |
CN100484539C (en) | Functional food with blood sugar reducing action and its preparing method | |
CN102987405B (en) | Method for preparing health food capsules by using cordyceps militaris and cocoon extracts | |
CN102987408B (en) | Method for extracting nutritional ingredients such as free amino acids from waste cordyceps militaris cocoons |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180904 |
|
RJ01 | Rejection of invention patent application after publication |