CN108423207B - Syringe pre-filling device - Google Patents
Syringe pre-filling device Download PDFInfo
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- CN108423207B CN108423207B CN201810264440.6A CN201810264440A CN108423207B CN 108423207 B CN108423207 B CN 108423207B CN 201810264440 A CN201810264440 A CN 201810264440A CN 108423207 B CN108423207 B CN 108423207B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B43/00—Forming, feeding, opening or setting-up containers or receptacles in association with packaging
- B65B43/42—Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up state; Feeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging position; Locating containers or receptacles at the filling position; Supporting containers or receptacles during the filling operation
- B65B43/52—Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up state; Feeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging position; Locating containers or receptacles at the filling position; Supporting containers or receptacles during the filling operation using roller-ways or endless conveyors
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B65/00—Details peculiar to packaging machines and not otherwise provided for; Arrangements of such details
- B65B65/003—Packaging lines, e.g. general layout
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B7/00—Closing containers or receptacles after filling
- B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
- B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a syringe pre-filling device, which comprises: the conveying chain can be clamped with the needle cylinder of the injector and is used for conveying the needle cylinder; the injector plugging mechanism is positioned at the periphery of the upstream of the conveying chain and used for extruding the soft plug into the bottom of the inner cavity of the syringe of the conveying chain; the syringe filling mechanism is positioned at the periphery of the midstream of the conveying chain and is used for filling liquid medicine into the plugged needle cylinder; and the injector cap screwing mechanism is positioned at the periphery of the downstream of the conveying chain and is used for screwing the cylinder cap to the lower end of the filled cylinder. The invention provides a brand-new pre-filling device for the syringe by designing a plunger adding mechanism, a filling mechanism and a cap screwing mechanism of the syringe, thereby saving the step of manually extracting liquid medicine during use, ensuring that the medicine is used more quickly, more conveniently and safely, and simultaneously improving the utilization rate of the liquid medicine.
Description
Technical Field
The invention belongs to the technical field of pharmaceutical machinery, and particularly relates to a pre-filling device of an injector.
Background
A syringe is a common medical device that primarily uses a needle to draw or inject a gas or liquid.
The medical market is changing and biotechnological therapies and the number of drug candidates that can be administered only by injection route are increasing, and they involve a very wide range of therapeutic fields. Some biotech drugs require frequent injections by a nurse, and at this time, the prefilled syringe eliminates some of the operation steps, making it faster and easier to use.
The nurse measures the drug from the vial into the syringe is a time consuming task, has high operational requirements, is prone to error, and often has difficulty in stabilizing the vial and measuring the correct dose.
Pre-filled syringes can significantly reduce the amount of product overfill. The use of the pre-filled syringe can save raw material medicines.
The prefilled syringe has the obvious advantages of safe medication, convenient use, high liquid medicine utilization rate and the like.
When the traditional full-glass syringe and the disposable plastic syringe are used, when liquid medicine is sucked or pushed through an injection needle, the liquid medicine in a medicine bottle or a bag always remains and cannot be completely utilized, and particularly, a small amount of valuable liquid medicine is easy to cause liquid medicine waste, and the dosage of the liquid medicine is insufficient, so that the medicine effect and the treatment effect are influenced. The inner cavity of the syringe is directly filled with liquid medicine, so that the utilization rate of the liquid medicine is improved, and the waste of the liquid medicine is reduced.
Disclosure of Invention
The invention provides a solution of a pre-filling device of a syringe, aiming at the problems that when the traditional syringe is used, liquid medicine cannot be completely utilized when the liquid medicine is sucked or pushed through a syringe needle, the liquid medicine is easily wasted, the dosage of the liquid medicine is insufficient, and the drug effect and the treatment effect are influenced.
The syringe prefilling device of the present invention comprises:
the conveying chain can be clamped with the needle cylinder of the injector and is used for conveying the needle cylinder;
the injector plugging mechanism is positioned at the periphery of the upstream of the conveying chain and used for extruding the soft plug into the bottom of the inner cavity of the syringe of the conveying chain;
the syringe filling mechanism is positioned at the periphery of the midstream of the conveying chain and is used for filling liquid medicine into the plugged needle cylinder;
and the injector cap screwing mechanism is positioned at the periphery of the downstream of the conveying chain and is used for screwing the cylinder cap to the lower end of the filled cylinder.
The syringe stopper mechanism comprises:
the plugging unit is used for placing the soft plug and can be positioned right above the conveying chain;
and the plug extruding unit is used for extruding the soft plug placed in the plug adding unit into the bottom of the inner cavity of the needle cylinder on the conveying chain.
And the cylinder blocking unit is positioned on one side of the conveying chain and used for blocking the needle cylinder from sliding off.
The plugging unit includes:
the plugging bottom plate is positioned above the conveying chain;
the plug channels are parallel to each other and used for transporting the soft plug, and the inner walls of the grooves on the two sides of the plug channels are respectively provided with a convex edge which can be clamped with the soft plug and guides the soft plug;
and the round holes vertically penetrate through the bottoms of the plug channels at one ends respectively and are used for dropping the soft plugs into the needle cylinders of the conveying chain.
The plug baffle is vertically fixed at one end of the plugging base plate close to the round hole and used for blocking the soft plug transported in the plug channel to prevent the soft plug from falling off;
the vibrating disc is internally provided with a plurality of soft plugs and is used for screening the soft plugs, the soft plugs circulate to the plug channel and flow into the position right above the round holes of the plug channel and can be blocked by the plug baffle.
The plug-squeezing unit has:
the plug extruding device comprises a plug extruding bracket and plug extruding shafts which respectively movably penetrate through the plug extruding bracket;
the two ends of the extrusion upper plate are respectively connected with the upper end of the plug extruding shaft, and a plurality of vertically downward extrusion needles are fixed on the extrusion upper plate, can be positioned right above the conveying chain needle cylinder and are used for poking the soft plug to enter the bottom of the inner cavity of the needle cylinder;
the two cams are positioned below the plug extruding bracket, are respectively connected with the lower part of the plug extruding shaft through a connecting rod, and drive the upper extruding plate to reciprocate up and down by the circular motion of the cams;
and the speed reducer is connected with the axes of the two cams and is used for driving the cams to do circular motion.
The barrier cylinder unit has:
the device comprises two retaining cylinder supports and two retaining cylinder shafts which respectively penetrate through the retaining cylinder supports;
the two ends of the U-shaped baffle are respectively connected to one side of the two baffle shaft and are used for resisting the side surface of the needle cylinder on the conveying chain so as to prevent the needle cylinder from separating from the conveying chain;
and the air cylinder is connected with the other sides of the two cylinder blocking shafts and used for pushing the cylinder blocking shafts to drive the U-shaped baffle to be far away from or close to the needle cylinder on the conveying chain.
The cam is a round wheel, the inner side of the round wheel is provided with an oval groove, and a ball is arranged in the groove and used for locking one end of the connecting rod
The U-shaped baffle is provided with a contact pad which is positioned on the inner side of the U-shaped baffle, the contact pad is provided with a plurality of arc-shaped pad grooves which are arranged at intervals, and the arc-shaped pad grooves are opposite to the conveying chain and used for covering the needle cylinders on the conveying chain to fix the needle cylinders.
The two sides of the contact pad are respectively provided with a slope surface for buffering the needle cylinder from sliding into the arc-shaped pad groove of the contact pad.
The syringe filling mechanism includes:
the transfusion unit is used for inputting liquid medicine;
and the liquid filling unit is used for filling the liquid medicine input by the infusion unit into the needle cylinder on the conveying chain.
And the cylinder pressing unit is positioned on one side of the conveying chain and used for pressing and blocking the needle cylinder from falling in the filling process.
The infusion unit is provided with a plurality of liquid medicine adjusting parts, and the liquid medicine adjusting parts are provided with:
the middle part of the hollow rod sleeve is provided with a liquid medicine inlet and a liquid medicine outlet, and the liquid medicine outlet is communicated with the liquid filling unit;
the ceramic rod is rotatably inserted into the hollow rod sleeve, two axially arranged medicine grooves are formed in the outer surface of the ceramic rod, and the two medicine grooves and the axial line of the ceramic rod are clamped by 90 degrees; after the ceramic rod is rotated, the medicine groove can be aligned to the medicine liquid inlet or the medicine liquid outlet of the hollow rod sleeve.
The infusion unit includes:
the infusion device comprises an infusion base and a top plate parallel to the infusion base;
the lower ends of the two side columns are respectively and vertically fixed at the two side ends of the upper surface of the infusion base; the upper ends of the upper ends are vertically fixed at the two side ends of the lower surface of the top plate;
a rotating shaft penetrating into one of the two side columns;
the speed reducer is positioned at the lower part of the infusion base and is in driving connection with the lower end of the rotating shaft;
the gears are meshed with each other in pairs and are positioned on the top plate, and the gears are in driving connection with the upper end of the rotating shaft;
the rod shafts penetrate through the top plate, the upper ends of the rod shafts are in driving connection with the gears, and the lower ends of the rod shafts are in driving connection with the ceramic rods;
the sleeve shafts penetrate through the infusion base, the upper ends of the sleeve shafts are in driving connection with the hollow rod sleeves, and the lower ends of the sleeve shafts are in driving connection with the servo motor.
The pressure cylinder unit has:
the two pressing cylinder supports and the two pressing cylinder shafts respectively and movably penetrate through the pressing cylinder supports;
the two ends of the pressing and blocking assembly are respectively connected to one side of the two pressing cylinder shafts and are used for pressing and blocking the side surface and the upper surface of the needle cylinder on the conveying chain so as to prevent the needle cylinder from jumping off;
and the air cylinder is connected with the other sides of the two pressing cylinder shafts and used for pushing the pressing cylinder shafts to drive the pressing and blocking assembly to be far away from or close to the needle cylinder on the conveying chain.
The pressure keeps off subassembly has:
the U-shaped baffle plate is provided with a contact pad which is positioned at the inner side of the U-shaped baffle plate, the contact pad is provided with a plurality of arc-shaped pad grooves which are arranged at intervals, the arc-shaped pad grooves can be opposite to the conveying chain, and the side surfaces of the arc-shaped pad grooves are covered with needle cylinders on the conveying chain to fix the needle cylinders;
and the lower surface of the horizontal pressing plate can be pressed on the top surface of the needle cylinder for preventing the needle cylinder from being extruded in the vertical direction during the filling process.
The two sides of the contact pad are respectively provided with a slope surface for buffering the needle cylinder from sliding into the arc-shaped pad groove of the contact pad; the horizontal pressing plate is provided with a slope surface and is used for buffering the needle cylinder from sliding into the lower surface of the pressing plate.
The liquid filling unit has:
the lower end of the liquid filling component is connected with the infusion unit and is used for receiving liquid medicine conveyed by the infusion unit;
and the lifting assembly penetrates through the liquid filling assembly and is used for lifting the liquid filling assembly to the lower end of the needle cylinder.
The liquid filling assembly has:
a plurality of infusion tubes for delivering the liquid medicine;
the infusion tube is sleeved with the infusion sleeves, and the upper parts of the infusion sleeves are provided with convex rings;
the connecting plugs are respectively fixed at the top end of the infusion tube and can be connected with the nozzle of the needle cylinder;
the springs are respectively sleeved outside the infusion sleeve, and the upper ends of the springs are abutted under the convex ring of the infusion sleeve;
the lifting assembly has:
the infusion tube is arranged on the plane rack in a penetrating mode at intervals, the lower portion of the infusion tube is arranged on the plane rack in a penetrating mode through a nut, and the lower end of the spring abuts against the plane rack;
the upper ends of the two lifting shafts are respectively fixed at the two ends of the rack;
and the two cams are respectively connected with the lower end of the lifting shaft and are used for lifting the lifting shaft and the plane rack when the cams do circular motion, so that the upper end of the infusion tube is driven to be butted with the lower end of the needle cylinder of the conveying chain.
The liquid medicine inlet and the liquid medicine outlet are symmetrically distributed on two sides of the hollow rod sleeve.
The cam is a round wheel, an oval groove is formed in the inner side of the round wheel, and a ball is arranged in the groove and used for locking the lower end of the lifting shaft.
The syringe cap screwing mechanism comprises:
the cover placing unit is used for placing a cylinder cover to be covered on the cylinder;
the stamping unit is used for stamping the cylinder placed on the cover placing unit away from the cover placing unit and entering a rotary cover unit;
the cap screwing unit is used for receiving the cylinder cap from the cap placing unit and screwing the cylinder cap at the lower end of the cylinder.
The cylinder blocking assembly comprises a cylinder pressing sheet and a cylinder blocking assembly; the cylinder pressing piece is fixed above the conveying chain and used for blocking the needle cylinder from moving upwards; the cylinder blocking part is positioned on one side of the conveying chain and used for preventing the needle cylinder from falling.
A plurality of round holes are arranged on the cylinder pressing sheet at intervals, the round holes are opposite to the needle cylinder on the conveying chain and used for detecting that the optical fiber penetrates into the needle cylinder,
the barrel stopper has:
two cylinder-resisting support columns;
the two ends of the U-shaped resistance plate are respectively connected with one end of each of the two cylinder-resistant pillars, the U-shaped resistance plate is provided with a plurality of block-shaped contact pads, the block-shaped contact pads are positioned on the inner side of the U-shaped resistance plate, each block-shaped contact pad is provided with an arc-shaped pad groove, each arc-shaped pad groove can be over against the conveying chain, and the side surface of each arc-shaped pad groove is covered with a cylinder on the conveying chain so as to fix the cylinder;
and the pistons of the small cylinders can movably penetrate through the U-shaped baffle plate and are respectively connected with the block-shaped contact pads so as to adjust the block-shaped contact pads to be far away from or close to the needle cylinders on the conveying chain.
The cover placing unit includes:
the cover placing base is provided with a cover channel on the upper surface, and the cover channel is communicated with the circular through hole on the bulge;
the cover supporting pieces are arranged oppositely in each pair and are respectively positioned on two sides of the bulge part, and each cover supporting piece is provided with a heavy end and a light end which is integrally formed with the heavy end; the heavy end is pivoted on the side edge of the cover placing base, the light end is provided with a thin crescent-shaped end portion, and the light end abuts against the lower surface of the protruding portion under the action of gravity and extends into the circular through hole of the protruding portion.
And the vibrating disk is internally provided with a plurality of cylinder covers for screening the circulation of the cylinder covers to the cover channels, flows into the circular through holes of the convex parts and can be supported by the cover supporting piece.
The stamping unit has:
the stamping device comprises a stamping support and two stamping shafts which respectively penetrate through two sides of the stamping support in a movable manner;
the two ends of the poking cover upper plate are respectively connected with the top end of the poking cover shaft, and a plurality of vertically downward poking cover rods are fixed on the poking cover upper plate and can be positioned right above the circular through holes of the convex parts, so that the poking cover upper plate is used for poking the cylinder covers placed on the cover placing units into the cover screwing units;
the two cams are positioned below the stamping cover bracket, are respectively connected with the lower end of the stamping cover shaft, and drive the stamping cover upper plate to reciprocate up and down by the circular motion of the cams;
and the motor is connected with the axis of the cam and is used for driving the cam to do circular motion.
The cam is a circular wheel, the inner side of the cam is provided with an oval groove, and a ball is arranged in the groove and used for locking the lower end of the poking cover shaft.
The cap screwing unit includes:
the cover screwing component can be positioned right below the circular through hole of the boss and is used for receiving the cylinder cover from the cover placing unit and screwing the cylinder cover to the lower end of the cylinder on the conveying chain;
the lifting component is arranged in a penetrating way and used for lifting the screwing cover component to the lower end of the needle cylinder.
The screw cap assembly has:
a plurality of rotary cover shafts are arranged at intervals;
the gears are meshed with each other pairwise, and the centers of the gears are respectively penetrated with the rotary cover shafts;
the motor is connected with the mutually meshed gears and drives the gears to rotate;
the cylinder cover can be placed in the cover heads, and the cover heads are screwed on the top end of the cover rotating shaft;
the lifting assembly has:
the middle part of the rotary cover shaft can movably penetrate through the rotary cover upper platform;
the horizontal cylinder is connected with the middle part of the upper rotary cover platform and is used for horizontally moving the rotary cover component;
the lower rotary cover platform is parallel to the upper rotary cover platform, and the bottom of the rotary cover shaft penetrates through the upper surface of the lower rotary cover platform;
and the lifting cylinder is connected with the lower surface of the lower platform of the screw cap and is used for vertically lifting the screw cap component.
The screw cap assembly has:
the shaft sleeves are respectively sleeved outside the rotary cover shafts;
the springs are respectively sleeved on the lower part of the rotary cover shaft, the upper end of the springs is abutted against the lower part of the shaft sleeve, and the lower end of the springs is abutted against the lower rotary cover platform.
The conveying chain is provided with a plurality of clamping cylinder blocks which are connected in series, the upper part of the side surface and the lower part of the side surface of each clamping cylinder block are respectively provided with an upper clamping plate and a lower clamping plate, and the corresponding positions of the upper clamping plate and the lower clamping plate are respectively provided with an arc-shaped clamping groove used for embedding the needle cylinder.
The positive progress effects of the invention are as follows: the invention provides a brand-new pre-filling device for the syringe by designing the plugging mechanism, the filling mechanism and the cap screwing mechanism of the syringe, thereby saving the step of manually extracting the liquid medicine during use, ensuring that the liquid medicine is used more quickly, more conveniently and safely, and simultaneously improving the utilization rate of the liquid medicine. .
The conception, the specific structure and the technical effects of the present invention will be further described with reference to the accompanying drawings to fully understand the objects, the features and the effects of the present invention.
Drawings
Fig. 1 is a perspective view of a syringe prefilling device of the present invention;
FIG. 2 is a perspective view of the conveyor chain of the present invention;
FIG. 3 is a perspective view of the syringe stopper mechanism of the present invention;
FIG. 4A is a perspective view of a stopper unit of the syringe stopper mechanism of the present invention;
FIG. 4B is a perspective view of the FIG. 4A from another angle;
FIG. 4C is an enlarged perspective view of the bottom plate;
FIG. 4D is an enlarged perspective view of the plug channel including the soft plug;
FIG. 5 is a perspective view of a plunger unit of the syringe plunger mechanism of the present invention;
FIG. 6A is a perspective view of the barrel unit of the syringe plugging mechanism of the present invention;
FIG. 6B is a perspective view of the combination of FIG. 6A and a conveyor chain at another angle;
FIG. 7 is a perspective view of the syringe filling mechanism of the present invention;
FIG. 8 is a perspective view of a liquid medicine metering device of an infusion unit of the syringe filling mechanism of the present invention;
FIG. 9 is a perspective view of the infusion unit of the syringe filling mechanism of the present invention;
FIG. 10 is a perspective view of the filling unit of the syringe filling mechanism of the present invention;
FIG. 11 is a partially enlarged perspective view of the fill assembly of the fill unit of the syringe filling mechanism of the present invention;
fig. 12A is a perspective view of a barrel pressing unit of the syringe filling mechanism of the present invention;
FIG. 12B is a perspective view of the structure of FIG. 12A from another angle;
FIG. 13 is a perspective view of the syringe cap screwing mechanism of the present invention;
FIG. 14A is a perspective view of a cap placing unit of the syringe cap screwing mechanism according to the present invention;
FIG. 14B is a partially enlarged perspective view of the cap placing unit of the syringe cap screwing mechanism of the present invention;
FIG. 14C is a perspective view of the FIG. 14B from another angle;
FIG. 15 is a perspective view of the covering unit of the syringe cover rotating mechanism of the present invention;
FIG. 16A is a perspective view of the cap screwing unit of the syringe cap screwing mechanism of the present invention;
FIG. 16B is a perspective view of the structure of FIG. 16A from another angle;
FIG. 16C is an enlarged partial perspective view of the cap-rotating assembly of the cap-rotating unit of the syringe cap-rotating mechanism of the present invention;
FIG. 17A is a perspective view of the barrel assembly of the syringe cap screwing mechanism of the present invention;
FIG. 17B is a perspective view of the structure of FIG. 17A at another angle;
fig. 17C is a perspective view of the combination of fig. 17A and a conveyor chain.
Detailed Description
As shown in fig. 1, the syringe prefilling apparatus of the present invention includes a conveyor chain 10, a syringe plugging mechanism 20, a syringe filling mechanism 30, and a syringe capping mechanism 40. The conveyor chain 10 can be used to clamp the syringes of the injector for conveying the syringes. And the injector plugging mechanism 20 is positioned at the periphery of the upstream of the conveying chain 10 and is used for extruding the soft plug into the bottom of the cavity of the syringe of the conveying chain 10. And the syringe filling mechanism 30 is positioned at the periphery of the midstream of the conveying chain 10 and is used for filling the liquid medicine into the plugged needle cylinder. And the injector cap screwing mechanism 40 is positioned at the periphery of the downstream of the conveying chain 10 and is used for screwing the cylinder cap to the lower end of the filled cylinder.
As shown in fig. 2, the conveying chain 10 has a plurality of cartridge blocks 12 connected in series, the upper side portion and the lower side portion of each cartridge block 12 are respectively provided with an upper cartridge 121 and a lower cartridge 122, and the corresponding positions of the upper cartridge 121 and the lower cartridge 122 are respectively provided with an arc-shaped slot 13 for inserting a syringe.
As shown in fig. 3, the injector plugging mechanism 20 includes a plugging unit 21, which can be used for placing soft plugs and can be located right above the conveying chain 10; a plug extruding unit 22 for extruding the soft plug placed in the plug adding unit 21 into the bottom of the inner cavity of the syringe on the conveying chain 10; and the cylinder blocking unit 23 is positioned on one side of the conveying chain 10 and used for blocking the needle cylinder from sliding off.
As shown in fig. 4A to 4D, the plugging unit 21 includes: the plugging base plate 211 is positioned above the conveying chain 10, the plugging base plate 211 is fixed on a linear feeder 218 (model: YQdc-190; manufacturer: Dongguan precise automation equipment Co., Ltd.), one side, close to the round hole 217, of the linear feeder 218 is lower, one side, far away from the round hole 217, of the linear feeder is higher, the linear feeder 218 is fixed on a plugging base 219, and the plugging base 219 is supported by two columns; the plug channels 212 are positioned on the upper surface of the plugging base plate 211, the plug channels 212 are parallel to each other and are used for transporting soft plugs, and the inner walls 213 of the slots on the two sides of the plug channels 212 are respectively provided with a convex rib 214 which can be clamped with the soft plugs and guides the soft plugs; the circular holes 217 are respectively and vertically penetrated through the groove bottom 215 at one end of the plug groove channel 212, and are used for soft plugs to fall into the needle cylinders of the conveying chain 10; the plug baffle plate 216 is vertically fixed at one end, close to the round hole 217, of the plugging base plate 211 and is used for blocking soft plugs transported in the plug channel 212 to prevent the soft plugs from falling; the vibrating disk (not shown) (manufacturer: Kunshan vibration quick automation device science and technology Co., Ltd.) is internally provided with a plurality of soft plugs for screening the soft plugs to flow to the plug channel 212, and flow into the position right above the circular hole 217 of the plug channel 212 and can be blocked by the plug baffle plate 216.
As shown in fig. 5, the jamming unit 22 has: a jamming bracket 221 and jamming shafts 222 movably penetrating the jamming bracket 221, respectively; the two ends of the extrusion upper plate 223 are respectively connected with the upper end of the extrusion plug shaft 222, and a plurality of vertically downward extrusion needles 224 are fixed on the extrusion upper plate 223, can be positioned right above the needle cylinder of the conveying chain 10 and are used for extruding the soft plug into the bottom of the inner cavity of the needle cylinder; two cams 225, located below the jam support 221, the cams 225 are connected with the lower part of the jam shaft 222 by connecting rods 226, the circumferential motion of the cams 225 drives the upper squeeze plate 223 to reciprocate up and down, the cams 225 are round wheels, the inner side of the cams 225 is provided with oval grooves 227, and balls 228 are arranged in the grooves for locking one end of the connecting rods 226; and the speed reducer 229 is connected with the axes of the two cams 225 and is used for driving the cams 225 to do circular motion.
As shown in fig. 6A to 6B, the shift cylinder unit 23 includes: two retainer cylinder supports 231 and two retainer cylinder shafts 232 which respectively penetrate through the retainer cylinder supports; the U-shaped baffle 233 is provided with a contact pad 234 which is positioned at the inner side of the U-shaped baffle 233 and is provided with a plurality of arc-shaped pad grooves 235 arranged at intervals, the arc-shaped pad grooves 235 are opposite to the conveying chain 10 and are used for covering the needle cylinders on the conveying chain 10 to fix the needle cylinders, and both sides of the contact pad 234 are respectively provided with a slope surface 236 which is used for buffering the sliding of the needle cylinders into the arc-shaped pad grooves 235 of the contact pad 234; and the air cylinder 237 is connected with the other sides of the two baffle shaft 232 and is used for pushing the baffle shaft 232 to drive the U-shaped baffle 233 to be far away from or close to the needle cylinder on the conveying chain 10.
As shown in fig. 7, the syringe filling mechanism 30 includes an infusion unit 31 for infusing a liquid medicine; the liquid filling unit 32 is used for filling the liquid medicine input by the infusion unit into a syringe on the conveying chain 10; and a cylinder pressing unit 33 located at one side of the conveying chain 10 and used for pressing and stopping the falling of the needle cylinder in the filling process.
As shown in fig. 8, the infusion unit 31 includes a plurality of drug solution dispensers 311, and the drug solution dispenser 311 includes: a hollow rod sleeve 3111, the middle part of which is provided with a liquid medicine inlet 3112 and a liquid medicine outlet 3113, and the liquid medicine outlet 3113 is communicated with a liquid conveying pipe 3211 of the liquid filling unit 32; a ceramic rod 3114 rotatably inserted into the hollow rod sleeve 3111, the ceramic rod 3114 having two axial medicine grooves 3115 on the outer surface thereof, the two medicine grooves 3115 and the axis of the ceramic rod 3114 being sandwiched at 90 ° with each other; after the ceramic rod 3114 is rotated, the medicine tank 3115 can be aligned with the medicine liquid inlet 3112 or the medicine liquid outlet 3113 of the hollow rod housing 3111, and the medicine liquid inlet 3112 and the medicine liquid outlet 3113 are symmetrically distributed on two sides of the hollow rod housing 3111. As shown in fig. 9, the infusion unit 31 further includes: an infusion base 312 and a top plate 313 parallel to the infusion base 312; two side columns 314, the lower ends of which are respectively vertically fixed on two side ends of the upper surface of the transfusion base 312; the upper ends of the upper ends are vertically fixed at the two side ends of the lower surface of the top plate 313; a rotation shaft penetrating into one side post 314 of the two side posts 314; the reducer 315 is positioned at the lower part of the infusion base 312 and is in driving connection with the lower end of the rotating shaft; a plurality of gears 316 which are meshed with each other in pairs and are positioned on the top plate 313, and the plurality of gears 316 are in driving connection with the upper end of the rotating shaft; a plurality of rod shafts 317 penetrating the top plate 313, the upper ends of which are in driving connection with the gear 316 and the lower ends of which are in driving connection with the ceramic rod 3114; a plurality of sleeve shafts 318 penetrate the transfusion base 312, the upper ends of the sleeve shafts 318 are in driving connection with the hollow rod sleeve 3111, and the lower ends are in driving connection with the servo motor 319.
As shown in fig. 10 to 11, the liquid filling unit 32 includes: a liquid filling unit 321 having a lower end connected to the infusion unit 31 and receiving the liquid medicine supplied from the infusion unit 31; the lifting component 322 is provided with a liquid filling component 321 in a penetrating way and used for lifting the liquid filling component 321 to the lower end of the needle cylinder.
The liquid filling unit 321 has: a plurality of infusion tubes 3211 for delivering the liquid medicine; a plurality of infusion sleeves 3212 which are sleeved outside the infusion tube 3211, wherein the upper part of the infusion sleeves 3212 is provided with a convex ring 3213; a plurality of connecting plugs 3214 which are respectively fixed at the top end of the transfusion tube 3211 and can be connected with the mouth of the syringe; a plurality of springs 3215 which are respectively sleeved outside the infusion sleeve 3212, and the upper ends of which abut against the lower part of a convex ring 3213 of the infusion sleeve 3212;
the lifting assembly 322 has: a plane bench 3221, on which infusion tubes 3211 are arranged at intervals, the lower part of the infusion tube 3211 is arranged on the plane bench 3221 by a nut, and the lower end of a spring 3215 is abutted against the plane bench 3221; the upper ends of the two lifting shafts 3222 are respectively fixed at two ends of the plane table 3221; two cams 3223 are respectively connected to the lower end of the lifting shaft 3222, and when the cams 3223 perform a circular motion, the cams are used for lifting the lifting shaft 3222 and the planar platform 3221, so as to drive the upper end of the infusion tube 3211 to abut against the lower end of the needle cylinder of the conveying chain 10, the cams 3223 are round wheels, and each of the round wheels has an oval groove 3224 on the inner side thereof, and a ball 3225 is disposed in the groove for locking the lower end of the lifting shaft 3222.
As shown in fig. 12A to 12B, the platen unit 33 includes: two pressing cylinder supports 331 and two pressing cylinder shafts 332 which respectively penetrate the pressing cylinder supports 331 movably; a blocking assembly 333, both ends of which are respectively connected to one side of the two syringe shafts 332, for blocking the lateral surface and the upper surface of the syringe on the conveying chain 10 to prevent the syringe from falling; the blocking member 333 has a U-shaped rail 3331, the U-shaped rail 3331 has a contact pad 3334 inside the U-shaped rail 3331, the contact pad 3334 has a plurality of arc-shaped pad slots 3335 spaced apart from each other, the arc-shaped pad slots 3335 are opposite to the conveying chain 10, the side surfaces of the contact pad 3334 cover the needle cylinder on the conveying chain 10 to fix the needle cylinder, and the two sides of the contact pad 3334 have slope surfaces 3336 respectively for sliding the buffer needle cylinder into the arc-shaped pad slots 3335 of the contact pad 3334; the pressing block component 333 also has a horizontal pressing plate 3332, the lower surface of the horizontal pressing plate 3332 can be pressed on the top surface of the syringe for preventing the syringe from being extruded in the vertical direction during the filling process, and the horizontal pressing plate 3332 also has a slope surface 3337 for buffering the sliding of the syringe into the lower surface of the horizontal pressing plate 3332; and the air cylinder 3333 is connected with the other sides of the two pressing cylinder shafts 332 and used for pushing the pressing cylinder shafts 332 to drive the U-shaped baffle 3331 to be far away from or close to the cylinders on the conveying chain 10.
As shown in fig. 13, the syringe cap screwing mechanism 40 includes a cap placing unit 41 for placing a cap to be fitted to the cylinder; a stamping unit 42 for moving the cartridge stamp placed on the placing and covering unit 41 away from the placing and covering unit 41 into a capping unit 43; a cap screwing unit 43 for receiving the cap from the cap placing unit 41 and screwing the cap to the lower end of the cylinder; a rail assembly 44.
As shown in fig. 14A to 14C, the capping unit 41 includes: a cover base 411, one side of which extends outward and is provided with a plurality of protrusions 4111 arranged at intervals, the protrusions 4111 are internally provided with circular through holes 4112 which are used for the cylinder cover to pass through and vertically penetrate through the protrusions 4111, the upper surface of the cover base 411 is provided with cover channels 4113, and the cover channels 4113 are communicated with the circular through holes 4112 on the protrusions 4111; the cover placing unit 41 further includes a vibrating tray (not shown) (manufacturer: Kun mountain Shaji Automation Equipment technologies, Ltd.), and a plurality of barrel covers are placed inside the vibrating tray, and are used for screening the barrel covers to flow into the cover grooves 4113, flow into the circular through holes 4112 of the protrusions 4111, and are supported by the cover supporting members 412; a plurality of pairs of cover supporting members 412, each pair of cover supporting members 412 is oppositely arranged and is respectively positioned at two sides of the bulge 4111, and each cover supporting member 412 is provided with a heavy end 4121 and a light end 4122 which is integrally formed with the heavy end 4121; the heavy end 4121 is pivotally connected to a side of the cover base 411, the light end 4122 has a thin crescent end 4123, the light end 4122 abuts against the lower surface of the protrusion 4111 under the action of gravity, and the thin crescent end 4123 extends into the circular through hole 4112 of the protrusion 4111. When the cartridge cover is located in the circular through hole 4112, the cartridge cover is held by the thin crescent-shaped end portions 4123 of the two holder members 412 disposed oppositely.
As shown in fig. 15, the stamping unit 42 has: a stamp-cover holder 421, and two stamp-cover shafts 422 movably penetrating both sides of the stamp-cover holder 421, respectively; the upper poking plate 423 is fixed on the upper poking plate 423, two ends of the upper poking plate 423 are respectively connected with the top end of the poking shaft 422, and a plurality of vertically downward poking rods 424 are fixed on the upper poking plate 423, can be positioned right above the circular through hole 4112 of the protrusion 4111, and are used for poking the cylinder cover placed on the circular through hole 4112 of the protrusion 4111 into the rotary cover unit 43; two cams 425 positioned below the stamp cover support 421, wherein the cams 425 are respectively connected with the lower end of the stamp cover shaft 422, and the upper stamp cover plate 423 is driven by the circular motion of the cams 425 to reciprocate up and down; and a motor 426 coupled to an axial center of the cam 425 for driving the cam 425 to move in a circular motion, wherein the cam 425 is a circular wheel having an oval groove 427 formed in an inner side thereof and a ball 428 formed therein for locking a lower end of the stamp cover shaft 422.
As shown in fig. 16A to 16C, the capping unit 43 includes: the screw cap assembly 431 can be positioned right below the circular through hole 4112 of the boss 4111, and is used for receiving the cylinder cap from the cap placing unit 41 and screwing the cylinder cap to the lower end of the cylinder on the conveying chain 10; a lifting component 432, through which the screw cap component 431 is arranged, for lifting the screw cap component 431 to the lower end of the syringe.
The screw cap assembly 431 has: a plurality of spiral cover shafts 4311 arranged at intervals; the gears 4312 are meshed with each other pairwise, and the centers of the gears 4312 are respectively provided with a rotary cover shaft 4311 in a penetrating way; a motor 4313 connected to the gear 4312 engaged with each other, for driving the gear 4312 to rotate; a plurality of cover heads 4314, wherein a cylinder cover is arranged in the cover heads 4314, and the cover heads 4314 are screwed on the top end of the cover screwing shaft 4311; the shaft sleeves 4315 are respectively sleeved outside the rotary cover shaft 4311; the springs 4316 are respectively sleeved on the lower part of the spiral cover shaft 4311, the upper ends of the springs 4316 are abutted against the lower part of the shaft sleeve 4315, and the lower ends of the springs 4316 are abutted against the lower spiral cover platform 4323.
The pulling assembly 432 has: the middle part of the screw cap shaft 4311 is movably arranged on the screw cap upper platform 4321 in a penetrating way; a horizontal cylinder 4322 connected to the middle of the cap-screwing upper platform 4321 for horizontally moving the cap-screwing assembly 431; a screw cap lower platform 4323 parallel to the screw cap upper platform 4321, the bottom of the screw cap shaft 4311 is arranged on the upper surface of the screw cap lower platform 4323 in a penetrating manner; and a lifting cylinder 4324 connected to a lower surface of the cap-screwing lower platform 4323 for vertically lifting the cap screwing assembly 431.
As shown in fig. 17A to 17C, the syringe cap screwing mechanism further includes:
a cylinder assembly 44, said cylinder assembly 44 comprising a cylinder pressing piece 441 and a cylinder blocking assembly 442; the cylinder pressing piece 441 is fixed above the conveying chain 10 and used for blocking the needle cylinder from moving upwards; the cylinder stopper 442 is located at one side of the conveyor chain 10 to prevent the needle cylinder from falling.
A plurality of round holes 4411 are formed in the cylinder pressing piece 441 at intervals, and the round holes 4411 are opposite to the cylinders on the conveying chain 10 and used for detecting that optical fibers penetrate into the cylinders;
the barrel stopper 442 has:
two cylinder support 4421;
a U-shaped resistance plate 4423, both ends of the U-shaped resistance plate 4423 are respectively connected to one end of the two cylinder-resistant supports 4421, the U-shaped resistance plate 4423 has a plurality of block-shaped contact pads 4424, the block-shaped contact pads 4424 are located inside the U-shaped resistance plate 4423, the block-shaped contact pads 4424 have arc-shaped pad slots 4425, the arc-shaped pad slots 4425 can be over against the conveying chain 10, and the side surfaces of the U-shaped resistance plate 4423 cover the cylinders on the conveying chain 10 to fix the cylinders;
a plurality of small air cylinders 4426, the pistons of the small air cylinders 4426 movably penetrate the U-shaped resistance plate 4423 and are respectively connected with the plurality of block-shaped contact pads 4424 to adjust the block-shaped contact pads 4424 to be far away from or close to the needle cylinders on the conveying chain 10.
The operating principle of the syringe prefilling device of the invention is as follows:
as shown in fig. 3, the cork is screened in a vibrating tray (not shown) (manufacturer: kunshan vibration agile automation equipment science and technology limited), and after being screened by vibration, the cylindrical surface of the cork is upward, the conical surface is downward, the cork enters a cork channel 212, and then the cork is conveyed to the position right above a round hole 217 and is blocked by a cork baffle 216.
The two cams 225 are driven by the decelerator 229 to make a circular motion, and the pressing pin 224 of the pressing upper plate 223 is driven to make a vertical downward motion, as shown in fig. 4A to 4D and fig. 5, the cork disposed right above the circular hole 217 passes through the circular hole 217 by the pressure of the pressing pin 224, and falls into the needle cylinder right below. As shown in fig. 6A to 6B, in the process, the air cylinder 237 drives the U-shaped baffle 233 of the cylinder blocking unit 23 to move horizontally and inwardly, and the arc-shaped pad groove 235 of the contact pad 234 on the inner side of the U-shaped baffle 233 on the cylinder blocking unit 23 covers the needle cylinder on the conveying chain 10 to prevent the needle cylinder from falling.
As shown in FIG. 5, the force applied by the squeeze pin 224 continues to squeeze the soft bung into the bottom of the interior chamber of the barrel.
After the stopper is added, the pressing pin 224 is driven by the decelerator 229 to move vertically upward to be separated from the cylinder. The U-shaped flap 233 moves horizontally outwards, away from the needle cylinder on the conveyor chain 10.
The conveyor chain 10 continues to move forward.
As shown in fig. 7, when the syringe transported by the conveyor chain 10 moves to a position right above the filling unit 32, the movement of the conveyor chain 10 is stopped.
As shown in fig. 8 to 9, the reducer 315 drives the gears 316 engaged with each other, so as to drive the ceramic rod 3114 on the upper portion of the infusion unit 31 to twist clockwise or counterclockwise, and when the medicine tank 3115 on the outer surface of the ceramic rod 3114 is twisted to align with the medicine liquid inlet 3112 of the hollow rod housing 3111, the hollow rod housing 3111 outside the ceramic rod 3114 is driven by the servo motor 319 to move vertically up and down, thereby drawing the medicine liquid to a certain dosage. After the liquid medicine is completely extracted, the ceramic rod 3114 is twisted again until the medicine groove 3115 on the outer surface of the ceramic rod 3115 is aligned with the liquid medicine outlet 3113 of the hollow rod sleeve 3111, and the liquid medicine flows from the infusion unit 31 to the filling unit 32.
As shown in fig. 10, when the liquid medicine flows into the filling unit 32, the two cams 3223 drive the filling assembly 32 to move vertically upward, and the movement stops after contacting the lower end of the syringe, so that the filling assembly 32 fills the liquid medicine into the syringe.
As shown in fig. 12A-12B, in the process, the air cylinder 3333 drives the U-shaped rail 3331 to move horizontally inward, and the arc-shaped groove 3335 of the inner contact pad 3334 covers the syringe on the conveying chain 10 to prevent the syringe from slipping off during filling. A horizontal pressing plate 3332 is fixed to the U-shaped rail 3331, and the lower surface of the horizontal pressing plate 3332 is pressed against the top surface of the cylinder to prevent the cylinder from being escaped in the vertical direction during the filling process.
After filling is complete, the fill assembly 32 is moved vertically away from the lower end of the syringe and the U-shaped rail 3331 is moved horizontally outward away from the syringe on the conveyor chain 10 as shown in fig. 7.
The conveyor chain 10 continues to move forward.
As shown in fig. 13, when the needle cylinder transported by the conveyor chain 10 moves to the opposite side of the U-shaped resistance plate 4423, the movement of the conveyor chain 10 is stopped.
As shown in fig. 14A to 14C, the cover is screened in a vibrating tray (not shown) (manufacturer: kunshan shangjie automation device technologies), after screening, the cover is placed into a cover groove 4113, which is communicated with the cover placing base 411, with the inner surface facing upward and the outer surface facing downward, and then is transported into a circular through hole 4112 of a protrusion 4111 on one side of the cover placing base 411 and is held by the cover holding member 412.
Subsequently, as shown in fig. 15, the poking rod 424 makes a vertical downward movement to drop the cartridge-poking placed on the circular through hole 4112 of the boss 4111 into the head 4314 of the screw-capping unit 43 as shown in fig. 16A to 16C.
As shown in fig. 17A to 17C, in the process, the horizontal cylinder 4322 drives the U-shaped resistance plate 4423 of the cylinder resistance part 441 to move horizontally inward, and after the arc-shaped pad groove 4425 of the block-shaped contact pad 4424 on the inner side of the U-shaped resistance plate 4423 covers the cylinder on the conveying chain 10, the cylinder is prevented from sliding down. A cylinder pressing piece 441 is fixed on the U-shaped baffle 4423, and the lower surface of the cylinder pressing piece 441 can be pressed on the top surface of the needle cylinder to prevent the needle cylinder from being extruded and fallen in the vertical direction during the cap screwing process.
As shown in fig. 13, the screw cap assembly 431 is driven by the lifting cylinder 4324 to move vertically upward until the cap 4314 contacts the lower end of the syringe, and the movement is stopped, and then the motor 4313 drives the gear 4312 on the screw cap assembly 431 to screw the syringe cap.
The screw cap assembly 431 moves vertically downward away from the lower end of the cylinder after the cylinder cap is screwed down. The U-shaped stop 4423 moves horizontally outward away from the needle cylinder on the conveyor chain 10.
The invention provides the injector pre-filling device in the liquid medicine pre-filling process, the liquid medicine is directly filled in the inner cavity of the needle cylinder, the liquid medicine utilization rate is improved, and the waste of the liquid medicine is reduced.
Claims (24)
1. A syringe prefill device, comprising:
the conveying chain can be clamped with the needle cylinder of the injector and is used for conveying the needle cylinder;
the injector plugging mechanism is positioned at the periphery of the upstream of the conveying chain and used for extruding the soft plug into the bottom of the inner cavity of the syringe of the conveying chain;
the syringe filling mechanism is positioned at the periphery of the midstream of the conveying chain and is used for filling liquid medicine into the plugged needle cylinder;
the injector cap screwing mechanism is positioned at the periphery of the downstream of the conveying chain and is used for screwing the cylinder cap to the lower end of the filled cylinder;
the syringe cap screwing mechanism comprises:
the cover placing unit is used for placing a cylinder cover to be covered on the cylinder;
the stamping unit is used for stamping the cylinder placed on the cover placing unit away from the cover placing unit and entering a rotary cover unit;
the cap screwing unit is used for receiving the cylinder cap from the cap placing unit and screwing the cylinder cap on the lower end of the cylinder;
the cover placing unit includes:
the cover placing base is provided with a plurality of protruding parts which are arranged at intervals and extend outwards from one side of the cover placing base, and a circular through hole which is used for the cylinder cover to pass through and vertically penetrates through the protruding parts is formed in the protruding parts;
the cover supporting pieces are arranged oppositely in each pair and are respectively positioned on two sides of the bulge part, and each cover supporting piece is provided with a heavy end and a light end which is integrally formed with the heavy end; the heavy end is pivoted on the side edge of the cover placing base, the light end is provided with a thin crescent-shaped end part, the light end abuts against the lower surface of the bulge part under the action of gravity, and the thin crescent-shaped end part extends into the circular through hole of the bulge part;
the stamping unit has:
the stamping device comprises a stamping support and two stamping shafts which respectively penetrate through two sides of the stamping support in a movable manner;
the two ends of the poking cover upper plate are respectively connected with the top end of the poking cover shaft, and a plurality of vertically downward poking cover rods are fixed on the poking cover upper plate and can be positioned right above the circular through holes of the convex parts, so that the poking cover upper plate is used for poking the cylinder covers placed on the cover placing units into the cover screwing units;
the two cams are positioned below the stamping cover bracket, are respectively connected with the lower end of the stamping cover shaft, and drive the stamping cover upper plate to reciprocate up and down by the circular motion of the cams;
the motor is connected with the axis of the cam and is used for driving the cam to do circular motion;
the cap screwing unit includes:
the cover screwing component can be positioned right below the circular through hole of the boss and is used for receiving the cylinder cover from the cover placing unit and screwing the cylinder cover to the lower end of the cylinder on the conveying chain;
the lifting component is arranged in a penetrating way and used for lifting the screwing cover component to the lower end of the needle cylinder.
2. Syringe prefill device according to claim 1, wherein: the syringe stopper mechanism comprises:
the plugging unit is used for placing the soft plug and can be positioned above the conveying chain;
and the plug extruding unit is used for extruding the soft plug placed in the plug adding unit into the bottom of the inner cavity of the needle cylinder on the conveying chain.
3. Syringe prefill device according to claim 2, wherein: the syringe stopper mechanism further comprises:
and the cylinder blocking unit is positioned on one side of the conveying chain and used for blocking the needle cylinder from sliding off.
4. Syringe prefill device according to claim 2, wherein: the plugging unit includes:
the plugging bottom plate is positioned above the conveying chain;
the plug channels are parallel to each other and used for transporting the soft plug, and the inner walls of the grooves on the two sides of the plug channels are respectively provided with a convex edge which can be clamped with the soft plug and guides the soft plug;
and the round holes vertically penetrate through the bottoms of the plug channels at one ends respectively and are used for dropping the soft plugs into the needle cylinders of the conveying chain.
5. Syringe prefill device according to claim 4, wherein: the plugging unit further includes:
the plug baffle is vertically fixed at one end, close to the round hole, of the plug adding bottom plate and used for blocking the soft plug transported in the plug channel from falling.
6. Syringe prefill device according to claim 5, wherein: the plug adding unit comprises a vibrating disc, a plurality of soft plugs are placed inside the vibrating disc and used for screening the soft plugs, the soft plugs circulate to the plug channels and flow into the plug channels, the soft plugs are right above the round holes and can be blocked by the plug baffle plates.
7. Syringe prefill device according to claim 2, wherein: the plug-squeezing unit has:
the plug extruding device comprises a plug extruding bracket and plug extruding shafts which respectively movably penetrate through the plug extruding bracket;
the two ends of the extrusion upper plate are respectively connected with the upper end of the plug extruding shaft, and a plurality of vertically downward extrusion needles are fixed on the extrusion upper plate, can be positioned right above the conveying chain needle cylinder and are used for poking the soft plug to enter the bottom of the inner cavity of the needle cylinder;
the two cams are positioned below the plug extruding bracket, are respectively connected with the lower part of the plug extruding shaft through a connecting rod, and drive the upper extruding plate to reciprocate up and down by the circular motion of the cams;
and the speed reducer is connected with the axes of the two cams and is used for driving the cams to do circular motion.
8. A syringe prefill device according to claim 3, wherein: the barrier cylinder unit has:
the device comprises two retaining cylinder supports and two retaining cylinder shafts which respectively penetrate through the retaining cylinder supports;
the two ends of the U-shaped baffle are respectively connected to one side of the two baffle shaft and are used for resisting the side surface of the needle cylinder on the conveying chain so as to prevent the needle cylinder from separating from the conveying chain;
and the air cylinder is connected with the other sides of the two cylinder blocking shafts and used for pushing the cylinder blocking shafts to drive the U-shaped baffle to be far away from or close to the needle cylinder on the conveying chain.
9. Syringe prefill device according to claim 8, wherein: the U-shaped baffle is provided with a contact pad which is positioned on the inner side of the U-shaped baffle, the contact pad is provided with a plurality of arc-shaped pad grooves which are arranged at intervals, and the arc-shaped pad grooves are opposite to the conveying chain and used for covering the needle cylinders on the conveying chain to fix the needle cylinders.
10. Syringe prefill device according to claim 1, wherein: the syringe filling mechanism includes:
the transfusion unit is used for inputting liquid medicine;
and the liquid filling unit is used for filling the liquid medicine input by the infusion unit into the needle cylinder on the conveying chain.
11. Syringe prefill device according to claim 10, wherein: the syringe filling mechanism further comprises:
and the cylinder pressing unit is positioned on one side of the conveying chain and used for pressing and blocking the needle cylinder from falling in the filling process.
12. Syringe prefill device according to claim 10, wherein: the infusion unit is provided with a plurality of liquid medicine adjusting parts, and the liquid medicine adjusting parts are provided with:
the middle part of the hollow rod sleeve is provided with a liquid medicine inlet and a liquid medicine outlet, and the liquid medicine outlet is communicated with the liquid filling unit;
the ceramic rod is rotatably inserted into the hollow rod sleeve, two axially arranged medicine grooves are formed in the outer surface of the ceramic rod, and the two axially arranged medicine grooves and the axial lead of the ceramic rod are clamped by 90 degrees; after the ceramic rod is rotated, the medicine groove can be aligned to the medicine liquid inlet or the medicine liquid outlet of the hollow rod sleeve.
13. Syringe prefill device according to claim 12, wherein: the infusion unit includes:
the infusion device comprises an infusion base and a top plate parallel to the infusion base;
the lower ends of the two side columns are respectively and vertically fixed at the two side ends of the upper surface of the infusion base; the upper ends of the upper ends are vertically fixed at the two side ends of the lower surface of the top plate;
a rotating shaft penetrating into one of the two side columns;
the speed reducer is positioned at the lower part of the infusion base and is in driving connection with the lower end of the rotating shaft;
the gears are meshed with each other in pairs and are positioned on the top plate, and the gears are in driving connection with the upper end of the rotating shaft;
the rod shafts penetrate through the top plate, the upper ends of the rod shafts are in driving connection with the gears, and the lower ends of the rod shafts are in driving connection with the ceramic rods;
the sleeve shafts penetrate through the infusion base, the upper ends of the sleeve shafts are in driving connection with the hollow rod sleeves, and the lower ends of the sleeve shafts are in driving connection with the servo motor.
14. Syringe prefill device according to claim 11, wherein: the pressure cylinder unit has:
the two pressing cylinder supports and the two pressing cylinder shafts respectively and movably penetrate through the pressing cylinder supports;
the two ends of the pressing and blocking assembly are respectively connected to one side of the two cylinder pressing shafts and are used for pressing and blocking the side surface and the upper surface of the cylinder on the conveying chain so as to prevent the cylinder from jumping off;
and the air cylinder is connected with the other sides of the two pressing cylinder shafts and used for pushing the pressing cylinder shafts to drive the pressing and blocking assembly to be far away from or close to the needle cylinder on the conveying chain.
15. Syringe prefill device according to claim 14, wherein: the pressure keeps off subassembly has:
the U-shaped baffle plate is provided with a contact pad which is positioned at the inner side of the U-shaped baffle plate, the contact pad is provided with a plurality of arc-shaped pad grooves which are arranged at intervals, the arc-shaped pad grooves can be opposite to the conveying chain, and the side surfaces of the arc-shaped pad grooves are covered with needle cylinders on the conveying chain to fix the needle cylinders;
the horizontal pressing plate is fixedly connected to the U-shaped baffle plate, and the lower surface of the horizontal pressing plate can be pressed on the top surface of the needle cylinder to prevent the needle cylinder from being extruded and falling in the vertical direction during the filling process.
16. Syringe prefill device according to claim 10, wherein: the liquid filling unit has:
the lower end of the liquid filling component is connected with the infusion unit and is used for receiving liquid medicine conveyed by the infusion unit;
and the lifting assembly penetrates through the liquid filling assembly and is used for lifting the liquid filling assembly to the lower end of the needle cylinder.
17. Syringe prefill device according to claim 16, wherein:
the liquid filling assembly has:
a plurality of infusion tubes for delivering the liquid medicine;
the infusion tube is sleeved with the infusion sleeves, and the upper parts of the infusion sleeves are provided with convex rings;
the connecting plugs are respectively fixed at the top end of the infusion tube and can be connected with the nozzle of the needle cylinder;
the springs are respectively sleeved outside the infusion sleeve, and the upper ends of the springs are abutted under the convex ring of the infusion sleeve;
the lifting assembly has:
the infusion tube is arranged on the plane rack in a penetrating mode at intervals, the lower portion of the infusion tube is arranged on the plane rack in a penetrating mode through a nut, and the lower end of the spring abuts against the plane rack;
the upper ends of the two lifting shafts are respectively fixed at the two ends of the rack;
and the two cams are respectively connected with the lower end of the lifting shaft and are used for lifting the lifting shaft and the plane rack when the cams do circular motion, so that the upper end of the infusion tube is driven to be butted with the lower end of the needle cylinder of the conveying chain.
18. Syringe prefill device according to claim 12, wherein: the liquid medicine inlet and the liquid medicine outlet are symmetrically distributed on two sides of the hollow rod sleeve.
19. Syringe prefill device according to claim 1, wherein: the syringe cap screwing mechanism further comprises:
the cylinder blocking assembly comprises a cylinder pressing sheet and a cylinder blocking assembly; the cylinder pressing piece is fixed above the conveying chain and used for blocking the needle cylinder from moving upwards; the cylinder blocking part is positioned on one side of the conveying chain and used for preventing the needle cylinder from falling.
20. The syringe prefill device of claim 19, wherein:
a plurality of round holes are formed in the cylinder pressing sheet at intervals, and the round holes are opposite to the needle cylinder on the conveying chain and used for detecting that the optical fibers penetrate into the needle cylinder;
the barrel stopper has:
two cylinder-resisting support columns;
the two ends of the U-shaped resistance plate are respectively connected with one end of each of the two cylinder-resistant support columns, the U-shaped resistance plate is provided with a plurality of block-shaped contact pads, the block-shaped contact pads are positioned on the inner sides of the U-shaped resistance plate, each block-shaped contact pad is provided with an arc-shaped pad groove, each arc-shaped pad groove can be over against the conveying chain, and the side surface of each arc-shaped pad groove is covered with a needle cylinder on the conveying chain so as to fix the needle cylinder;
and the pistons of the small cylinders can movably penetrate through the U-shaped baffle plate and are respectively connected with the block-shaped contact pads so as to adjust the block-shaped contact pads to be far away from or close to the needle cylinders on the conveying chain.
21. Syringe prefill device according to claim 1, wherein:
the upper surface of the cover placing base is provided with a cover channel communicated to the circular through hole on the boss;
the cover placing unit further comprises a vibrating disc, a plurality of cylinder covers are placed inside the vibrating disc and used for screening the cylinder covers, the cylinder covers circulate to the cover channels and flow into the circular through holes of the protruding portions, and the cylinder covers can be supported by the cover supporting pieces.
22. Syringe prefill device according to claim 1, wherein:
the screw cap assembly has:
a plurality of rotary cover shafts are arranged at intervals;
the gears are meshed with each other pairwise, and the centers of the gears are respectively penetrated with the rotary cover shafts;
the motor is connected with the mutually meshed gears and drives the gears to rotate;
the cylinder cover can be placed in the cover heads, and the cover heads are screwed on the top end of the cover rotating shaft;
the lifting assembly has:
the middle part of the rotary cover shaft can movably penetrate through the rotary cover upper platform;
the horizontal cylinder is connected with the middle part of the upper rotary cover platform and is used for horizontally moving the rotary cover component;
the lower rotary cover platform is parallel to the upper rotary cover platform, and the bottom of the rotary cover shaft penetrates through the upper surface of the lower rotary cover platform;
and the lifting cylinder is connected with the lower surface of the lower platform of the screw cap and is used for vertically lifting the screw cap component.
23. The syringe prefill device of claim 22, wherein: the screw cap assembly has:
the shaft sleeves are respectively sleeved outside the rotary cover shafts;
the springs are respectively sleeved on the lower part of the rotary cover shaft, the upper end of the springs is abutted against the lower part of the shaft sleeve, and the lower end of the springs is abutted against the lower rotary cover platform.
24. Syringe prefill device according to claim 1, wherein: the conveying chain is provided with a plurality of clamping cylinder blocks which are connected in series, the upper part of the side surface and the lower part of the side surface of each clamping cylinder block are respectively provided with an upper clamping plate and a lower clamping plate, and the corresponding positions of the upper clamping plate and the lower clamping plate are respectively provided with an arc-shaped clamping groove used for embedding the needle cylinder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810264440.6A CN108423207B (en) | 2018-03-28 | 2018-03-28 | Syringe pre-filling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810264440.6A CN108423207B (en) | 2018-03-28 | 2018-03-28 | Syringe pre-filling device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108423207A CN108423207A (en) | 2018-08-21 |
| CN108423207B true CN108423207B (en) | 2020-04-21 |
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| CN201810264440.6A Active CN108423207B (en) | 2018-03-28 | 2018-03-28 | Syringe pre-filling device |
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| CN111806776B (en) * | 2020-07-15 | 2022-04-05 | 长沙一星制药机械有限公司 | Prefilled syringe filling and sealing machine |
| CN114684397A (en) * | 2022-05-07 | 2022-07-01 | 安徽徽科生物工程技术有限公司 | Accurate filling equipment of gel suppository |
| CN116215930B (en) * | 2023-02-20 | 2024-07-23 | 湖南科伦制药有限公司 | Filling and plugging machine for syringe |
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|---|---|---|---|---|
| CN201095593Y (en) * | 2007-10-17 | 2008-08-06 | 朱文忠 | Filling cap-rotating machine |
| CN201634405U (en) * | 2009-12-04 | 2010-11-17 | 顾志伟 | Disposable injector filling and plugging machine |
| CN102838063B (en) * | 2012-09-29 | 2014-06-04 | 山东淄博民康药业包装有限公司 | Pre-encapsulating glass syringe vacuum plugging method |
| CN105173147B (en) * | 2015-08-07 | 2017-04-12 | 南京固延机械有限公司 | Pre-filled injector filling machine |
| CN204873794U (en) * | 2015-08-21 | 2015-12-16 | 上海都能制药机械设备有限公司 | Syringe liquid filling capper |
| CN206051525U (en) * | 2016-09-21 | 2017-03-29 | 上海都能制药机械设备有限公司 | Full-automatic syringe liquid filling and sealing machine |
| CN106697419B (en) * | 2016-12-14 | 2022-10-28 | 山东新华医疗器械股份有限公司 | Syringe filling capper |
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2018
- 2018-03-28 CN CN201810264440.6A patent/CN108423207B/en active Active
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| Publication number | Publication date |
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| CN108423207A (en) | 2018-08-21 |
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