CN108420459A - A kind of blood vessel endoscope imaging probe and imaging method - Google Patents
A kind of blood vessel endoscope imaging probe and imaging method Download PDFInfo
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- 238000003384 imaging method Methods 0.000 title claims abstract description 61
- 239000000523 sample Substances 0.000 title claims abstract description 48
- 210000004204 blood vessel Anatomy 0.000 title claims abstract description 43
- 230000002792 vascular Effects 0.000 claims abstract description 23
- 239000000835 fiber Substances 0.000 claims abstract description 20
- 238000004026 adhesive bonding Methods 0.000 claims description 5
- 239000011521 glass Substances 0.000 claims description 5
- 238000006243 chemical reaction Methods 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 2
- 238000011835 investigation Methods 0.000 abstract description 4
- 230000000694 effects Effects 0.000 description 5
- 208000024172 Cardiovascular disease Diseases 0.000 description 4
- 208000026106 cerebrovascular disease Diseases 0.000 description 4
- 230000002526 effect on cardiovascular system Effects 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000012014 optical coherence tomography Methods 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000003759 clinical diagnosis Methods 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 210000004351 coronary vessel Anatomy 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000002608 intravascular ultrasound Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000001839 endoscopy Methods 0.000 description 1
- 230000007274 generation of a signal involved in cell-cell signaling Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 235000009566 rice Nutrition 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00163—Optical arrangements
- A61B1/00165—Optical arrangements with light-conductive means, e.g. fibre optics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0661—Endoscope light sources
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
- A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0891—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
- A61B8/5238—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
- A61B8/5261—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from different diagnostic modalities, e.g. ultrasound and X-ray
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Abstract
The present invention relates to a kind of blood vessel endoscope imaging probe and imaging methods, probe includes cylindrical shell, it is disposed with ultrasonic transducer and prism in an axial direction in the cylindrical shell, the ultrasonic transducer is electrically connected with signal processor, the prism with the matched multimode fibre of the prism by being connected to laser, ultrasonic projection region of the ultrasonic transducer on vascular wall partially overlaps with laser projection region of the prism on the vascular wall, there is angle with from the prism to the incident line direction in the laser projection region from the ultrasonic transducer to the incident line direction in the ultrasonic projection region.Technical solution provided by the invention can take into account the investigation depth and image quality of blood vessel endoscope imaging probe.
Description
Technical field
The present invention relates to the field of medical instrument technology more particularly to a kind of blood vessel endoscope imaging probes and imaging method.
Background technology
Cardiovascular and cerebrovascular disease has become one of the principal disease for seriously affecting health of people life, according to statistics, the whole world
There are up to ten million people to die of cardiovascular and cerebrovascular disease every year.The origin cause of formation of cardiovascular and cerebrovascular disease is mainly to be grown in atherosclerosis blood
Vulnerable plaque in pipe ruptures suddenly, and arteries is caused to block, to make blood vessel blood supply interrupt, final threat to life.
At present medically before making a definite diagnosis cardiovascular and cerebrovascular disease, it usually needs by probe using imaging means to heart and brain
Vulnerable plaque in blood vessel is observed, using observed image as the Clinical Basis of later stage diagnosis and treatment and evidence.Common imaging hand
Section includes Optical coherence tomography (OCT) and blood vessel endoscope ultrasonic imaging (IVUS) etc..But these common imaging skills
Art there are problems that.The imaging resolution of OCT is higher, and image quality is preferable, but investigation depth is inadequate, is only capable of detection imaging
The surface at position can not detect the deep for being imaged position.IVUS is then on the contrary, can be used to visit the deep for being imaged position
It surveys, but its resolution ratio is relatively low, image quality is poor.
Invention content
The investigation depth and image quality of blood vessel endoscope imaging probe in order to balance, the present invention provide a kind of blood vessel endoscope at
As probe and imaging method.
The present invention provides a kind of blood vessel endoscope imaging probe, including cylindrical shell, in the cylindrical shell in an axial direction
Be disposed with ultrasonic transducer and prism, the ultrasonic transducer is electrically connected with signal processor, the prism by with institute
It states the matched multimode fibre of prism and is connected to laser, ultrasonic projection region and institute of the ultrasonic transducer on vascular wall
It states laser projection region of the prism on the vascular wall to partially overlap, from the ultrasonic transducer to the ultrasonic projection area
The incident line direction in domain has angle with from the prism to the incident line direction in the laser projection region.
The advantageous effect of blood vessel endoscope imaging probe provided by the invention is：It, will be in probe when carrying out blood vessel endoscope
Cylindrical shell equipped with ultrasonic transducer and prism and the part fiber being connect with prism are put into blood vessel, and it is made to prolong along blood vessel
Direction is stretched, that is, is moved axially.Shell can be all-transparent material, or be equipped on the projecting direction of laser and ultrasonic wave
Transparent window.The prism at rear portion will be generated by laser in shell and the laser refraction conducted through multimode fibre is projected to blood
On tube wall, form laser projection region, be located at front in shell ultrasonic transducer receive the reflection of laser projection region because swashing
The feedback ultrasonic wave sent out vascular tissue's heating and generated, and it is converted into electric signal, ultrasonic transducer is connected by conducting wire
Signal processor can be based on photoacoustic imaging principle and generate that resolution ratio is higher and the preferable photoacoustic image of image quality according to this signal.
Meanwhile ultrasonic transducer can also emit ultrasonic wave, and receive by the ultrasonic wave of its own transmitting in ultrasonic projection region because swashing
It sends out vascular tissue's heating and reflects the feedback ultrasonic wave generated, after being converted to electric signal, signal processor can be based on super simultaneously
Acoustic imaging principle generates ultrasonoscopy according to this signal.Due to the projected area part of ultrasonic transducer and prism on vascular wall
Overlap and the incident line have certain angle, so on the one hand ensure ultrasonic transducer can and meanwhile receipt source in its own and prism
Reflect ultrasonic wave, and because ultrasonic transducer is presented axially in front of prism, the ultrasonoscopy for making signal processor generate
There is the investigation depth of bigger relative to photoacoustic image, and the two is not easy to interfere.On the other hand, axially disposed coaxial rib
Mirror and ultrasonic transducer can make the radial dimension of probe entirety substantially be less than existing radially arranged prism and ultrasonic transduction
The probe size of device keeps probe operation more flexible.
Based on the above technical solution, the present invention can also be improved as follows.
Further, the ultrasonic projection region is circle, and the laser projection region is ellipse.
Further, the incident line of rearmost end and the laser projection region be in an axial direction in an axial direction in the ultrasonic projection region
The range of the angle of the incident line of front end is 15 ° to 25 °.
Advantageous effect using above-mentioned further scheme is：When being observed into blood vessel due to probe, it usually needs edge
Blood vessel extending direction, that is, move axially, and direction of the probing shell far from laser and signal processor can be considered as to front, leaned on
Close direction is considered as rear.Since ultrasonic projection region and laser projection region partly overlap, make laser signal and ultrasonic wave
There is superposition in signal, the signal strength of the two overlapping region is stronger compared to the signal strength of respective isolated area, in this way can be with
Improve the axial visual effect of optoacoustic and the imaging of ultrasonic double-mode formula.In addition, by adjusting between ultrasonic transducer and prism away from
From making the incident lines of two projected areas, there are 15 ° to 25 ° of angles, ensure that the axial operating distance of probe, maximum reachable
6.5 millimeter.
Further, the jointing end face of the prism and the multimode fibre is lived by UV gluings.
Advantageous effect using above-mentioned further scheme is：Lived with UV gluings be all cylinder and the prism that is mutually matched and
Multimode fibre can reduce the reflection loss of light at the two joint interface.
Further, the jointing end face outer of the prism and the multimode fibre is arranged with glass capillary.
Advantageous effect using above-mentioned further scheme is：One can be reserved in the glass capillary that joint outer is arranged
The interface of air/prism, to reach the total reflection of light path.
Further, the core diameter of the multimode fibre is 200 microns.
Further, the ultrasonic transducer is single array element ultrasonic transducer.
Further, the full-size of the ultrasonic transducer is less than or equal to 1 millimeter.
Further, the length of the cylindrical shell is less than or equal to 4 millimeters.
Advantageous effect using above-mentioned further scheme is：The energy converter of micromation can further expand the application model of probe
It encloses, it is made to can be used for coronary artery blood vessel and capillary based endoscopic imaging.The length of probe cylindrical shell may be less than or equal to 4 millis
Rice, diameter may be less than or equal to 6 millimeters.
The present invention also provides a kind of blood vessel endoscope imaging methods, are applied to above-mentioned blood vessel endoscope imaging probe, including：
Step 1, prism will be generated by laser and the laser refraction conducted through multimode fibre is projected on vascular wall, be formed
Laser projection region；
Step 2, on ultrasonic transducer direct projection projection ultrasonic wave to vascular wall, ultrasonic projection region is formed；
Step 3, ultrasonic transducer receives the first feedback ultrasonic wave of laser projection region reflection respectively and ultrasonic wave is thrown
Penetrate the second feedback ultrasonic wave of region reflection；
Step 4, signal processor is according to the signal converted by the first feedback ultrasonic wave and by the second feedback ultrasonic wave conversion
Signal generate optoacoustic and ultrasonic double-mode formula imaging.
Since ultrasonic imaging is to provide image comparison based on acoustic impedance difference, and photoacoustic imaging is to be based on optical absorption coefficient
Difference provides image comparison, and the image that two imaging patterns obtain can provide different information, the letter of this Double-mode imaging
Breath can complementary and verification mutually.Make that there is the blood vessel endoscope of coaxial optoacoustic and ultrasonic double-mode state imaging function to pop one's head in while meeting
By the depth and resolution requirement at imaging position, subsequent clinical diagnosis can be given to provide abundanter information.
Description of the drawings
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technology description to be briefly described, it should be apparent that, the accompanying drawings in the following description is this hair
Some bright embodiments for those of ordinary skill in the art without having to pay creative labor, can be with
Obtain other attached drawings according to these attached drawings.
Fig. 1 is the hot spot schematic diagram that blood vessel endoscope image optics probe is incident upon on vascular wall；
Fig. 2 is the structural schematic diagram of the blood vessel endoscope imaging probe of the embodiment of the present invention；
Fig. 3 is the flow diagram of the blood vessel endoscope imaging method of the embodiment of the present invention.
Specific implementation mode
The principle and features of the present invention will be described below with reference to the accompanying drawings, and the given examples are served only to explain the present invention, and
It is non-to be used to limit the scope of the present invention.
Since traditional optoacoustic endoscopy system optics probe segment light path does not focus, so the laser being emitted from optic probe
It is elliptical shape in the projection hot spot of vascular wall, and central light strength is most strong, intensity gradually weakens around.As shown in Figure 1, hot spot
Axially distributed length is Z, and the radially distributed length of hot spot is H, Z compares radial direction, in axial direction always greater than H
The light path distribution bigger in direction.
Since the acoustical range in ultrasonic transducer is fixed, keep sound wave and light path lap bigger,
Imaging signal will be stronger.So in order on the basis of not increasing probe size and probe makes complexity, will be changed on probe
The arrangement mode of energy device 2 and prism 3 is set as front and back axial alignment, can make the axial operating distance of probe wider in this way.
As shown in Fig. 2, blood vessel endoscope imaging probe provided in an embodiment of the present invention includes cylindrical shell 1, it is cylindrical outer
Ultrasonic transducer 2 and prism 3 are disposed in shell 1 in an axial direction, ultrasonic transducer 2 is electrically connected with signal processor 4, prism 3
By being connected to laser 6, ultrasonic projection area of the ultrasonic transducer 2 on vascular wall 9 with 3 matched multimode fibre 5 of prism
Domain 7 partially overlaps with laser projection region 8 of the prism 3 on vascular wall 9, from ultrasonic transducer 2 to ultrasonic projection region 7
Incident line direction has angle with from prism 3 to the incident line direction in laser projection region 8.
In the present embodiment, when carrying out blood vessel endoscope, the cylinder of ultrasonic transducer and prism will be equipped in probe
Shell and the part fiber being connect with prism are put into blood vessel, and make it along blood vessel extending direction, that is, move axially.Shell can
Think all-transparent material, or is equipped with transparent window on the projecting direction of laser and ultrasonic wave.The rib at rear portion in shell
Mirror will be generated by laser and the laser refraction conducted through multimode fibre is projected on vascular wall, form laser projection region, position
Ultrasonic transducer in front in shell receives the feedback of laser projection region reflection generated because exciting vascular tissue's heating
Ultrasonic wave, and it is converted into electric signal, the signal processor of ultrasonic transducer is connected by conducting wire can be based on photoacoustic imaging original
Manage and image quality preferable photoacoustic image higher according to this signal generation resolution ratio.Meanwhile ultrasonic transducer can also emit it is super
Sound wave, and receive and reflect generation because exciting vascular tissue's heating in ultrasonic projection region by the ultrasonic wave of its own transmitting
Ultrasonic wave is fed back, after being converted to electric signal, it is super according to the generation of this signal that signal processor can be based on ultrasonic imaging principle simultaneously
Acoustic image.Due to the projected area of ultrasonic transducer and prism on vascular wall partially overlap and the incident line have certain angle,
On the one hand ensure in this way ultrasonic transducer can receipt source reflecting ultrasonic wave in its own and prism simultaneously, and because ultrasound is changed
Energy device is presented axially in front of prism, and the ultrasonoscopy that signal processor generates is made to have the spy of bigger relative to photoacoustic image
Depth measurement degree, and the two is not easy to interfere.On the other hand, axially disposed coaxial prism and ultrasonic transducer can make probe whole
The radial dimension of body is substantially less than the probe size of existing radially arranged prism and ultrasonic transducer, makes probe operation more
Flexibly.
Preferably, ultrasonic projection region 7 is circle, and laser projection region 8 is ellipse.
Preferably, the incident line of rearmost end and laser projection region 8 front end in an axial direction in an axial direction of ultrasonic projection region 7
The incident line angle, that is, the range of β is 15 ° to 25 °.
When being observed into blood vessel due to probe, it usually needs along blood vessel extending direction, that is, move axially, can will visit
Direction of the head shell far from laser and signal processor is considered as front, and close direction is considered as rear.Due to ultrasonic projection
Region and laser projection region partly overlap, and laser signal and ultrasonic signal is made to there is superposition, the signal of the two overlapping region
Intensity is stronger compared to the signal strength of respective isolated area, and the axial direction that can improve optoacoustic and the imaging of ultrasonic double-mode formula in this way can
Visual effect fruit.In addition, by adjusting the distance between ultrasonic transducer and prism, making the incident lines of two projected areas, there are 15 °
To 25 ° of angle, the axial operating distance of probe ensure that, it is maximum up to 6.5 millimeters.
Preferably, prism 3 and the jointing end face of multimode fibre 5 are lived by UV gluings.
It is all cylinder and the prism and multimode fibre that are mutually matched to be lived with UV gluings, can be reduced at the two joint interface
Reflection loss of light.
Preferably, prism 3 and the jointing end face outer of multimode fibre 5 are arranged with glass capillary.
The interface of an air/prism can be reserved in the glass capillary that joint outer is arranged, to reach the complete of light path
Reflection.
Preferably, the core diameter of multimode fibre 5 is 200 microns.
Preferably, ultrasonic transducer 2 is single array element ultrasonic transducer.
Preferably, the full-size of ultrasonic transducer 2 is less than or equal to 1 millimeter.
Preferably, the length of cylindrical shell 1 is less than or equal to 4 millimeters.
The energy converter of micromation can further expand the application range of probe, it is made to can be used for coronary artery blood vessel and capillary
Based endoscopic imaging.The length of probe cylindrical shell may be less than or equal to 4 millimeters, and diameter may be less than or equal to 6 millimeters.
The embodiment of the present invention also provides a kind of blood vessel endoscope imaging method, is applied to above-mentioned blood vessel endoscope imaging probe, such as
Shown in Fig. 3, this method includes：
Step 1, prism will be generated by laser and the laser refraction conducted through multimode fibre is projected on vascular wall, be formed
Laser projection region.
Step 2, on ultrasonic transducer direct projection projection ultrasonic wave to vascular wall, ultrasonic projection region is formed.
Step 3, ultrasonic transducer receives the first feedback ultrasonic wave of laser projection region reflection respectively and ultrasonic wave is thrown
Penetrate the second feedback ultrasonic wave of region reflection.
Step 4, signal processor is according to the signal converted by the first feedback ultrasonic wave and by the second feedback ultrasonic wave conversion
Signal generate optoacoustic and ultrasonic double-mode formula imaging.
Since ultrasonic imaging is to provide image comparison based on acoustic impedance difference, and photoacoustic imaging is to be based on optical absorption coefficient
Difference provides image comparison, and the image that two imaging patterns obtain can provide different information, the letter of this Double-mode imaging
Breath can complementary and verification mutually.Make that there is the blood vessel endoscope of coaxial optoacoustic and ultrasonic double-mode state imaging function to pop one's head in while meeting
By the depth and resolution requirement at imaging position, subsequent clinical diagnosis can be given to provide abundanter information.
Reader should be understood that in the description of this specification reference term " one embodiment ", " is shown " some embodiments "
The description of example ", " specific example " or " some examples " etc. mean specific features described in conjunction with this embodiment or example, structure,
Material or feature are included at least one embodiment or example of the invention.In the present specification, above-mentioned term is shown
The statement of meaning property need not be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described
It may be combined in any suitable manner in any one or more of the embodiments or examples.In addition, without conflicting with each other, this
The technical staff in field can be by the spy of different embodiments or examples described in this specification and different embodiments or examples
Sign is combined.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all the present invention spirit and
Within principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of blood vessel endoscope imaging probe, which is characterized in that including cylindrical shell (1), the interior edge of the cylindrical shell (1)
It axially is disposed with ultrasonic transducer (2) and prism (3), the ultrasonic transducer (2) is electrically connected with signal processor (4),
The prism (3) with the prism (3) matched multimode fibre (5) by being connected to laser (6), the ultrasonic transducer
(2) the ultrasonic projection region (7) on vascular wall (9) and laser projection area of the prism (3) on the vascular wall (9)
Domain (8) partially overlaps, the incident line direction from the ultrasonic transducer (2) to the ultrasonic projection region (7) with from described
Prism (3) to the incident line direction of the laser projection region (8) has angle.
2. blood vessel endoscope imaging probe according to claim 1, which is characterized in that the ultrasonic projection region (7) is
Circle, the laser projection region (8) are ellipse.
3. blood vessel endoscope imaging probe according to claim 2, which is characterized in that ultrasonic projection region (7) edge
The range of the incident line of axial rearmost end and the laser projection region (8) angle of the incident line of front end in an axial direction is 15 °
To 25 °.
4. blood vessel endoscope imaging probe according to claim 1, which is characterized in that the prism (3) and the multimode light
The jointing end face of fine (5) is lived by UV gluings.
5. blood vessel endoscope imaging probe according to claim 4, which is characterized in that the prism (3) and the multimode light
The jointing end face outer of fine (5) is arranged with glass capillary.
6. blood vessel endoscope imaging probe according to claim 5, which is characterized in that the core diameter of the multimode fibre (5) is
200 microns.
7. blood vessel endoscope imaging probe according to claim 1, which is characterized in that the ultrasonic transducer (2) is Dan Zhen
First ultrasonic transducer.
8. blood vessel endoscope imaging probe according to claim 7, which is characterized in that the maximum of the ultrasonic transducer (2)
Size is less than or equal to 1 millimeter.
9. according to claim 1 to 8 any one of them blood vessel endoscope imaging probe, which is characterized in that the cylindrical shell
(1) length is less than or equal to 4 millimeters.
10. a kind of blood vessel endoscope imaging method is applied on claim 1 to 9 any one of them blood vessel endoscope imaging probe,
It is characterized in that, the method includes：
Step 1, prism will be generated by laser and the laser refraction conducted through multimode fibre is projected on vascular wall, form laser
Projected area；
Step 2, on ultrasonic transducer direct projection projection ultrasonic wave to vascular wall, ultrasonic projection region is formed；
Step 3, ultrasonic transducer receives the first feedback ultrasonic wave and the ultrasonic projection area of laser projection region reflection respectively
Second feedback ultrasonic wave of domain reflection；
Step 4, signal processor is according to the signal converted by the first feedback ultrasonic wave and by the letter of the second feedback ultrasonic wave conversion
Number generate optoacoustic and ultrasonic double-mode formula imaging.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117122262A (en) * | 2023-04-11 | 2023-11-28 | 深圳信息职业技术学院 | Positioning method for endoscope acquired image and endoscope system |
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