CN108399938A - Stochastic system based on network answer and recall random method - Google Patents

Stochastic system based on network answer and recall random method Download PDF

Info

Publication number
CN108399938A
CN108399938A CN201711477693.3A CN201711477693A CN108399938A CN 108399938 A CN108399938 A CN 108399938A CN 201711477693 A CN201711477693 A CN 201711477693A CN 108399938 A CN108399938 A CN 108399938A
Authority
CN
China
Prior art keywords
random
subject
drug
interface
recalling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711477693.3A
Other languages
Chinese (zh)
Inventor
肖亮
赵桂云
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiaxing Tai Mei Medical Science And Technology Co Ltd
Original Assignee
Jiaxing Tai Mei Medical Science And Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiaxing Tai Mei Medical Science And Technology Co Ltd filed Critical Jiaxing Tai Mei Medical Science And Technology Co Ltd
Priority to CN201711477693.3A priority Critical patent/CN108399938A/en
Publication of CN108399938A publication Critical patent/CN108399938A/en
Pending legal-status Critical Current

Links

Landscapes

  • Medical Treatment And Welfare Office Work (AREA)

Abstract

The present invention provides a kind of stochastic system based on network answer and random method is recalled, is included the following steps:It receives and recalls random request in the subject of stochastic regime;Random request is recalled described in response, is withdrawn the random number for being assigned to the subject, so that the subject is reverted to non-stochastic regime, and the random number is made to revert to free state.

Description

Stochastic system based on network answer and recall random method
Technical field
The invention mainly relates to field of computer data processing more particularly to a kind of stochastic system and recall random side Method.
Background technology
Random experiment design in clinical research is the test sequence that each factor is arranged according to randomized algorithm, purpose It is that systematic error is made to be converted into random error, and the characteristic mutually compensated for using random error, to reduce test error.Random examination Test also known as randomized controlled trial.Object to participating in research carries out randomized grouping, can avoid artificially selective bias, makes Two or more sets objects into experiment are consistent as far as possible in baseline characteristic, i.e. the statistically comparativity between group, this Sample could guarantee test result it is true and reliable.By randomized grouping, the patient into each test group can be made in gender, year Many known and X factors for influencing prognosis such as age, disease severity, course of disease length are balancedly distributed to each group as far as possible In, can just learn in this way any one final result between group existing difference only because caused by the difference of intervening measure, and Be not as being unevenly distributed of patient characteristic, prognosis it is different and caused by.Before new drug lists, often to carry out it is multinomial with Machine check experiment is to prove validity and the safety of drug.Randomization repeats together with blind, sample, is the three of clinical research A basic principle.In order to reduce the science of test error and repeated explanation clinical research, clinical research is use up when satisfying the requirements Amount uses method of randomization.
With the development of Internet technology and mobile communication, the randomisation process of clinical research is increasingly intended to using letter The stochastic system of breathization, such as Internet answering system (Interactive Web Response System, IWRS) come in fact It is existing.When using IWRS, the process that executes randomization includes two processes with distribute medicine at random, corresponds to subject respectively and obtains It obtains a random number and corresponds to the other drug number for the treatment of group with the random number.
The clinical research carried out before the listing of one drug easily ten million so that hundreds of millions yuan of input, guarantee be randomized The correct operation of journey, it can be ensured that the science for the progress and research that clinical research is carried out is striven for for the sponsor of clinical research The result of clinical research is obtained as early as possible and wins more favorable condition for listing.Therefore, in carrying out clinical test, it is ensured that face Bed experiment is random correctly to have apparent social value.
In clinical test randomisation process, due to maloperation etc., row stochastic subject should not be held by mistake Ground has run random function, and subject is made to obtain random number, is designated as some experiment group, while being possible to be designated one A other drug number of respective sets.The case where accidentally being occupied which results in random number and possible drug number.If with Machine number and drug number are accidentally occupied, and random district's groups can be destroyed, and are violated the Random Design principle of clinical research, are contrary to research Science.
Invention content
The technical problem to be solved in the present invention is to provide a kind of stochastic system based on network answer and recall random side Method can restore the random number accidentally occupied.
In order to solve the above technical problems, recalling random method the present invention provides a kind of, include the following steps:Receive needle Random request is recalled to the subject in stochastic regime;Recall random request described in response, withdrawal be assigned to it is described by The random number of examination person makes the subject revert to non-stochastic regime, and the random number is made to revert to free state.
In one embodiment of this invention, the above method further includes:Random request is recalled described in response, withdrawal is assigned to institute The drug number for stating subject makes the drug number revert to free state.
In one embodiment of this invention, the above method further includes:It receives for recalling in the subject of dispensing Medication request;Medication request is recalled described in response, is withdrawn the drug number for being assigned to the subject, is kept the drug number extensive It is free state again.
In one embodiment of this invention, it receives for the step for recalling random request in the subject of stochastic regime Suddenly include:Include to recall random button at the random interface of the subject, to recall random request described in reception.
In one embodiment of this invention, it receives for wrapping the step of recalling medication request in the subject of dispensing It includes:Include to recall drug button at the random interface of the subject, to recall medication request described in reception.
In one embodiment of this invention, it receives for the step for recalling random request in the subject of stochastic regime Suddenly include:Random interface is recalled in offer, described to recall random interface including recalling reason dialog box;It receives and recalls reason by described The information inputted by dialog box.
In one embodiment of this invention, receive in the subject of stochastic regime recall random request after Further include:Approval is provided and recalls interface;Receive the approval operation that interface input is recalled by the approval.
In one embodiment of this invention, it receives and is gone back the step of recalling medication request in the subject of dispensing Including:Drug interface is recalled in offer, and the drug interface of recalling includes recalling reason dialog box;It receives and recalls reason by described The information of dialog box input.
In one embodiment of this invention, it receives and is also wrapped later for the medication request of recalling in the subject of dispensing It includes:Approval is provided and recalls interface;Receive the approval operation that interface input is recalled by the approval.
In one embodiment of this invention, it withdraws after being assigned to the random number of the subject and further includes:It is having the right Limit the use of the trace being deleted comprising the random number on the subject interface at family.
In one embodiment of this invention, it withdraws after being assigned to the drug number of the subject and further includes:It is having the right Limit the use of the trace being deleted comprising the drug number on the subject interface at family.
In one embodiment of this invention, the above method further includes:Release the random number and the drug number Correspondence.
In one embodiment of this invention, the above method further includes:The subject that random request is directed to is recalled described in forbidding The drug number being retracted is specified in dispensing for the first time later.
The present invention also proposes a kind of stochastic system based on network answer, including:Memory, can be by processor for storing The instruction of execution;And processor, for executing described instruction to realize method as described above.
The present invention also proposes a kind of computer storage media, is stored thereon with computer instruction, wherein working as computer instruction When being executed by processor, method as described above is executed.
Compared with prior art, the present invention can restore the random number accidentally occupied, to which random number can be weighed Newly used.If the subject also specifies a drug number after missing at random, this mistiming occupies drug number and is also resumed, It can be used again.After the random number and/or drug number that accidentally occupy are resumed, the random process of follow-up clinical research In can reuse the above-mentioned random number being resumed and drug number, and entire random and drug distribution process is not by shadow It rings.Therefore present invention can assure that clinical test is correct at random.
Description of the drawings
Fig. 1 is the randomization flow chart of one embodiment of the invention.
Fig. 2 is that one embodiment of the invention recalls random device flow chart.
Fig. 3 is that another embodiment of the present invention recalls random device flow chart.
Fig. 4 A-4D are subject's random process schematic diagrames of one embodiment of the invention.
Fig. 5 A-5D are that one embodiment of the invention recalls random process schematic diagram.
Fig. 6 A-6C are that one embodiment of the invention recalls pharmaceutical procedures schematic diagram.
Fig. 7 is the hardware implementation environment schematic diagram of one embodiment of the invention.
Fig. 8 is the block diagram of the stochastic system of one embodiment of the invention.
Specific implementation mode
For the above objects, features and advantages of the present invention can be clearer and more comprehensible, below in conjunction with attached drawing to the tool of the present invention Body embodiment elaborates.
Many details are elaborated in the following description to facilitate a thorough understanding of the present invention, still the present invention can be with Implemented different from other manner described here using other, therefore the present invention do not limited by following public specific embodiment System.
As shown in the application and claims, unless context clearly prompts exceptional situation, " one ", "one", " one The words such as kind " and/or "the" not refer in particular to odd number, may also comprise plural number.It is, in general, that term " comprising " only prompts to wrap with "comprising" Include clearly identify the step of and element, and these steps and element do not constitute one it is exclusive enumerate, method or equipment The step of may also including other or element.
The embodiment of the present invention describes stochastic system and recalls random method.Stochastic system is typically answered based on network The stochastic system answered, such as Internet answering system (IWRS).IWRS use random device be generally divided into static random and Dynamic random.Static random refers to before random operation, and the corresponding experiment group of random number has been determined;Dynamic random is then It is to be needed according to one experiment group of test situation and random algorithm acquisition at that time when obtaining random number.Below the present invention Embodiment static random is illustratively described.In such cases, random number and each is set in stochastic system in advance Treatment group corresponding to random number.
Clinical research often refers to the measure of a variety for the treatment of processing, including drug, medical instrument, physics, laser, radiation Deng.For the ease of narration, many kinds of measures of " drug " representative " treatment processing " is used in the term described below.
Fig. 1 is the randomization flow chart of one embodiment of the invention.With reference to figure 1, the random process of the present embodiment can be wrapped probably The subject that includes step 101 is random, it is step 103 recall it is random and step 104 again random.It is random to execute in step 101 When person's random operation, the random interface of some subject can be logged in, runs random function, stochastic system can be subject specified one A random number, while the subject is assigned to some treatment group.While random process or after terminating, subject Drug number can also be obtained.At this point, stochastic system be subject specify a drug number, theoretically the drug number with should Some treatment group that random number is distributed is consistent.When random executor or other users having permission are in step When 102 discovery random numbers above-mentioned are accidentally occupied, it can indicate that stochastic system executes step 103.In step 103, can log in The random interface of subject, operation recall function at random.After above-mentioned steps, the random number accidentally occupied is resumed, can To be used again.If the subject also specifies a drug number after accidentally random, this mistiming occupy drug number also by Restore, can be used again.When accidentally occupy random number and/or drug number be resumed after, follow-up clinical research with The above-mentioned random number being resumed and drug number can be reused during machine, and entire random and drug distribution process is not It is impacted.
In order to realize above-mentioned process, some states can be set in stochastic system.It is appreciated that the setting of state is simultaneously Nisi, the boundary between state can may as the case may be adjust.
Such as subject, non-stochastic regime and stochastic regime can be set.Non- stochastic regime for example, it can be set to For:Subject plans to participate in randomized clinical studies, but without the process for executing randomization, there is no random number and divides With the corresponding group of random number.Stochastic regime is for example, it can be set to be:If some subject meets participation clinical research Condition and participate in the randomized clinical studies, randomization first obtains a random number, and is assigned to the random number The corresponding experiment group of code.
Such as random number, can there are occupied state and free state.Occupied state for example, it can be set to For:Random number has been assigned to some subject.Free state is for example, it can be set to be:Random number is not yet designated To subject.
Similarly, for drug number, can there are occupied state and free state.Occupied state can for example be set It is set to:Drug number has been assigned to some subject.Free state is for example, it can be set to be:Drug number is not yet referred to Determine to subject.
Here, it includes normal the case where occupying that random number is occupied, also include the case where accidentally occupancy.Such as in certain research Heart faulty operation has run stochastic system, and has occupied random number, and such situation belongs to random number and accidentally occupies, and subsequently should Random number can not be used.If it is correct to give tacit consent to the process, stochastic system is continued to run with, it will lead to the random number accidentally occupied Code cancels, then will produce district's groups destruction, influences the normal use of random device.In the research having, result even in random Harmonious destruction between group, serious damage is brought to the science of clinical research.
Similarly, it includes normal the case where occupying that drug number is occupied, also includes the case where accidentally occupancy.Such as it is random Afterwards, a kind of situation is at random while the corresponding group of random number has been determined in subject, but temporarily need not also distribute medicine number Code, selects the other drug number of some correspondence group from drug reservoir again when to be needed.And another situation is that system is possible Some other drug number of designated groups can be selected in drug reservoir immediately, the drug number is also accidentally occupied at this time, is caused follow-up The drug number can not be used.No matter which kind of situation, random number accidentally occupy patient occupy a drug number, all belong to It is accidentally occupied in drug number.
It may include from being not used here, random number is not used, also include missing after occupancy is restored to be reused.Namely It says, accidentally occupies random number and be resumed back, can be used again in subsequent research.The random number has reused The corresponding subject of random maloperation before being likely to occur in, it is also possible to be happened at other subjects.
It may include from being not used here, drug number is not used, also include missing after occupancy is restored to be reused.Namely It says, accidentally occupies drug number and be resumed back, can be used again in subsequent research.The drug number has reused The corresponding subject of random maloperation before being likely to occur in, it is also possible to be happened at other subjects.
Fig. 4 A-4D are subject's random process schematic diagrames of one embodiment of the invention.Shown in Fig. 4 A, at interface 410, allow random executor to start random process, random executor's selection parameter, such as random fashion are may also allow for before starting To create subject, random number is distributed;Or to create subject, distribution random number and dispensing.Then it clicks " next Step ", the interface 420 of triggering Fig. 4 B.At interface 420, random executor is allowed to input subject number 421 and initials 422. Then " submission " button 423 is clicked, the interface 430 of triggering Fig. 4 C confirms random information for random executor.In " determination " button After 431 are clicked, the interface 440 of triggering Fig. 4 D.It may include random number 441 and drug number 442 in this interface 440.Such as Fruit drug number is not specified immediately, and " manual dispensing " button 443 can be selected to carry out specific drug number.
In clinical test, subject press enter experiment the priority time difference, successively obtain system distribution one with Machine number.In general, these random numbers generate in sequence, such as 01001,01002,01003, etc..Sometimes It waits possible first number to appear not to be with 1 ending (not being minimum), for example is 01005.Sometimes random number is arranged in order Row, it may appear that interrupt, system distributes a number without what relationship, and new number is sequentially allocated by the way of restarting Code, such as 01009,01010,01011,01012,01021,01022....But regardless of number is which kind of above-mentioned order, these Random number is all to design to be stored in the database of stochastic system in advance.
Random number is divided into two kinds of situations with the other relationship of corresponding test group, and one is pre-set, another kinds It is that quantity of the subject between test group determines the corresponding experiment group of current random number according to a kind of algorithm before.
Trial drug can be belonging respectively to different experiment groups, for subject receive drug be numbered, it is same by The drug number that examination person obtains always belongs to the same experiment group.One subject may obtain multiple drug numbers.
Random and distribute medicine process is that some subject enters experiment, and stochastic system first distributes a random number, The subject obtains corresponding experiment group by above-mentioned rule simultaneously;When subject's dispensing medicament, a drug number is obtained, The corresponding group of the number i.e. the corresponding group of random number.Sometimes, random number is exactly drug number;When some It waits, random number is not directly dependent upon with drug number, and only corresponding experiment group is consistent.
Subject is in non-stochastic regime before not obtaining random number, once obtaining random number, state reforms into Stochastic regime.One drug number, if not yet distributing to any one subject by system, drug number is vacant State;If being allocated to some subject by system, it is occupied state to belong to drug number.
Increase " recalling a random " button 444 at the random interface 440 of subject, can to the random number that accidentally occupies into Row is recalled.When random executor has found accidentally random, he can be allowed through click and " recall random " button 444 to initiate to recall Random request.
Fig. 2 is that one embodiment of the invention recalls random device flow chart.In conjunction with shown in A-5D referring to figs. 2 and 5, this reality The random device of recalling for applying example includes the following steps:
In step 201, includes to recall random button at the random interface of subject, random request is recalled to receive.
As shown in Figure 5A, " recalling random " button 511 is may include on random interface 510, is asked at random for receiving to recall It asks.
In step 202, receives and recall random request in the subject of stochastic regime.
With continued reference to Fig. 5 A, in one example, when " recalling random " button 511 is selected, it is believed that receive and remove Return random request.In another example, when " recalling random " button 511 is selected, it can trigger and recall random interface 512, It is completed etc. random interface 512 is recalled and after " preservation " button selected, just thinks to receive to recall random request.Preferably, It includes recalling reason dialog box 513 to recall random interface 512, and random executor is needed to select and/or indicate to recall random original Cause.Reason in menu includes but not limited to the options such as " maloperation ", " other ";When selecting " other " menu, dialogue can be popped up Frame, it is desirable that fill in definite reason in the form of text.System can receive the information by recalling the input of reason dialog box 513.
In step 203, can ratify to recall random request.
For example, with reference to shown in figure 5B, approval is provided and recalls interface 520, show revocation request, and have and recall reason By explanation.The approval operation that the input of interface 520 is recalled by approval is can receive, such as " approval " button 521 is selected.
According to experimental design, revocation request may obtain the approval of related personnel, for example place research unit mainly grinds The approval for the person of studying carefully and/or the approval of the responsible principal investigator of the clinical research project.Preferably, ratification process is divided into two steps, The first step is ratified by the principal investigator in the research center, and second step is criticized by the principal investigator for being responsible for the clinical research project It is accurate.
It is appreciated that when experimental design be not so require when, step 203 is just not essential.
In step 204, random number is withdrawn.
In step 205, drug number is withdrawn.
With reference to figure 5C, in interface 530, recall random.The random number and drug number of subject are distributed at this time It is retracted, includes to recall random entry 531 in interface.Subject reverts to non-stochastic regime.Random number and drug number Code reverts to free state.Accidentally occupying random number and drug number can be reused.
In addition, after step 205, can also be deleted comprising random number on the subject interface for have permission user Trace.Such as in the interface of Fig. 5 D 540, the random number 541 still as it can be seen that but show deleted label simultaneously.This State is exactly accidentally to occupy after random number recalls, and accidentally occupies the deletion state of random number.
Similarly, after step 205, it can be also deleted comprising drug number on the subject interface for have permission user Trace.This state is exactly accidentally to occupy the deletion state that drug number is accidentally occupied after drug number is recalled.
Here, it may include stochastic system guardian to have permission user, but do not include the random and relevant research people of dispensing Member.
Due to maloperation, it is possible to also specify a corresponding drug number while obtaining random number, then makes mistake It occupies random number and accidentally occupies drug number and establish one-to-one relationship.This correspondence in some cases may Convenient for discovering the experiment group corresponding to random or drug, to destroy randomization and the blind of clinical research.In order to eliminate This is influenced, and in one example, after step 205, can release the correspondence of the random number and drug number of recovery. In another example, a mechanism can be generated, in accidentally randomized subjects' dispensing for the first time, forbids specifying above-mentioned one-to-one correspondence That accidentally occupy drug number.Such case can also make accidentally to occupy random number and accidentally occupy drug number correspondence solution It removes.
In addition, when also unallocated drug number in random process, step 205 is dispensed, process simplification Fig. 3 Shown in flow chart.
After drug number is assigned, there is the demand for individually recalling drug.Therefore it can receive in dispensing Subject recall medication request, be then responding to this and recall medication request, withdraw the drug number for distributing to subject, make medicine Object number reverts to free state.Such as pharmaceutical procedures schematic diagram is recalled with reference to shown in figure 6A-6C.It, can be with first such as Fig. 6 A Dispensing entry at interface 610 provides " recalling " button 611.In one example, when " recalling random " button 611 is selected When, it is believed that it receives and recalls medication request.In another example, it when " recalling random " button 611 is selected, can trigger Drug interface 620 is recalled such as Fig. 6 B, is waited and is recalled drug interface 620 and be completed and after " preservation " button 621 selected, just recognize Random request is recalled to receive.Preferably, it includes recalling reason dialog box 622 to recall random interface 620, random executor is needed It selects and/or indicates to recall random reason.Reason in menu includes but not limited to the options such as " maloperation ", " other ";Choosing When selecting " other " menu, dialog box can be popped up, it is desirable that fill in definite reason in the form of text.System can be received by recalling reason The information that dialog box 622 inputs.Later, can ratify to recall medication request.Please process can refer to and recall random request, herein not It is reinflated.As shown in Figure 6 C, interface 630 includes to recall the entry 631 of dispensing, and it is free state to restore drug number D50, Enable mistake to occupy drug number to be reused.
Randomization example according to the ... of the embodiment of the present invention is set forth below.
It is randomized example 1:
The first step:Random executor's (maloperation), random step is performed at the random interface of some subject.It is random at this time System specifies a random number automatically.Stochastic system and the corresponding drug number of the not specified random number.
Second step:Random executor accidentally occupies the random interface of subject in random number, and random button is recalled in click, this When interface pop-up recall the menu of reason, random executor selects " maloperation ", and submits.
Third walks:The principal investigator in the research center obtains withdrawal of an application at the random interface of subject and reminds, and checks and removes Return reason, it is believed that can recall, be ratified.
4th step:The principal investigator for being responsible for the clinical research project obtains withdrawal of an application at the random interface of subject and carries It wakes up, checks and recall reason, it is believed that can recall, be ratified.
5th step:The state of subject from becoming not random at random, and accidentally random number is by recalling random operation.It is right In with checking for the user of permission, which still can be seen, but show deleted label simultaneously.
6th step:Some subject executes correct random, the subject acquisition occupied random number of maloperation.
It is randomized example 2:
The first step:Random executor's (maloperation), random step is performed at the random interface of some subject.It is random at this time System specifies a random number automatically, and stochastic system also specifies the corresponding drug number of the random number at this time.
Second step:Random executor accidentally occupies the random interface of subject in random number, and random button is recalled in click, this When interface pop-up recall the menu of reason, random executor selects " maloperation ", and submits.
Third walks:The principal investigator in the research center obtains withdrawal of an application at the random interface of subject and reminds, and checks and removes Return reason, it is believed that can recall, be ratified.
4th step:The principal investigator for being responsible for the clinical research project obtains withdrawal of an application at the random interface of subject and carries It wakes up, checks and recall reason, it is believed that can recall, be ratified.
5th step:The state of subject from becoming not random at random.For with checking for the user of permission, accidentally with By recalling random operation, which still can be seen machine number, but show deleted label simultaneously;Tested The random interface of person, after accidentally occupancy random process is withdrawn, accidentally occupying drug number still can be seen, but shows deleted simultaneously The label removed.
6th step:Some subject executes correct random, the subject acquisition occupied random number of maloperation, at this time Obtain dispensing number for the first time;The number cannot accidentally occupy that the drug number specified before random number, but mutually take an entrance examination Test another other drug number of group.
6th step:When some subject's dispensing medicament, the above-mentioned drug number accidentally occupied is obtained.
Fig. 7 is the hardware implementation environment schematic diagram of one embodiment of the invention.Refering to what is shown in Fig. 7, system may include client computer 710 and stochastic system 720, the two connected by network 730.Network 730 can with various known wired or wireless networks, This is not reinflated.Server 720 and the cooperation of client computer 710 are to realize method described in previous embodiment or its change case.Visitor User interface, communication port and input module can be equipped in family machine 410.Various boundaries can be presented to user in user interface Face, input module can receive the input of user.As an example, input module may include one kind or more of component below Kind:Mouse, trace ball, keyboard, touch control component, sound receiver etc..
Fig. 8 is the block diagram of the stochastic system of one embodiment of the invention.Stochastic system 720 may include internal communication bus 801, Processor (processor) 802, read-only memory (ROM) 803, random access memory (RAM) 804, communication port 805, with And hard disk 807.The data communication of 720 inter-module of stochastic system may be implemented in internal communication bus 801.Processor 802 can be into Row judges and sends out prompt.In some embodiments, processor 802 can be made of one or more processors.Communication port 805 may be implemented between stochastic system 720 and such as client computer 710 of outside into row data communication.In some embodiments, with Machine system 720 can send by communication port 805 from network and receive information and data.Stochastic system 720 can also include Various forms of program storage units and data storage element, such as hard disk 807, read-only memory (ROM) 803 and are deposited at random Access to memory (RAM) 804 can store computer disposal and/or communicate the various data files used and processor 802 Performed possible program instruction.Processor executes these instructions with the major part of implementation method.The knot of processor processing Fruit is transmitted to client computer 710 by communication port, is shown in the user interface of client computer 710.
For example, above-mentioned randomisation process may be embodied as computer program, be stored in hard disk 807, and can remember It is downloaded in processor 802 and executes, to implement the present processes.
When randomisation process is embodied as computer program, it can also store in a computer-readable storage medium as system Product.For example, computer readable storage medium can include but is not limited to magnetic storage apparatus (for example, hard disk, floppy disk, magnetic stripe), light Disk (for example, compact disk (CD), digital versatile disc (DVD)), smart card and flash memory device are (for example, electrically erasable is only Read memory (EPROM), card, stick, key driving).In addition, various storage media described herein can be represented for storing information One or more equipment and/or other machine readable medias.Term " machine readable media " can include but is not limited to store, Including and/or the carrying code and/or wireless channel and various other media (and/or storage medium) of instruction and/or data.
It should be understood that embodiments described above is only signal.Embodiment described herein can be in hardware, software, solid It is realized in part, middleware, microcode or its arbitrary combination.For hardware realization, processing unit can be in one or more spy Determine purposes integrated circuit (ASIC), digital signal processor (DSP), digital signal processing appts (DSPD), programmable logic device It part (PLD), field programmable gate array (FPGA), processor, controller, microcontroller, microprocessor and/or is designed as executing Other electronic units of function described herein or its combine interior realization.
In addition, be clear that unless stated otherwise or from context to refer to singulative, otherwise the application and institute The indefinite article used in attached claims should be typically interpreted as the meaning of expression " one or more ".
Although the present invention is described with reference to current specific embodiment, those of ordinary skill in the art It should be appreciated that above embodiment is intended merely to illustrate the present invention, can also make in the case of no disengaging spirit of that invention Go out various equivalent change or replacement, therefore, as long as to the variation of above-described embodiment, change in the spirit of the present invention Type will all be fallen in the range of following claims.

Claims (15)

1. a kind of recalling random method, include the following steps:
It receives and recalls random request in the subject of stochastic regime;
Random request is recalled described in response, withdraws the random number for being assigned to the subject, the subject is made to revert to not Stochastic regime, and the random number is made to revert to free state.
2. according to the method described in claim 1, it is characterized in that, further including:
Random request is recalled described in response, withdraws the drug number for being assigned to the subject, the drug number is made to revert to Free state.
3. according to the method described in claim 1, it is characterized in that, further including:
It receives and recalls medication request in the subject of dispensing;
Medication request is recalled described in response, withdraws the drug number for being assigned to the subject, the drug number is made to revert to Free state.
4. according to the method described in claim 1, it is characterized in that, receiving for recalling in the subject of stochastic regime The step of random request includes:Include to recall random button at the random interface of the subject, it is random to be recalled described in reception Request.
5. according to the method described in claim 3, recalling drug in the subject of dispensing it is characterized in that, receiving The step of request includes:Include to recall drug button at the random interface of the subject, to recall medication request described in reception.
6. according to the method described in claim 4, it is characterized in that, receiving for recalling in the subject of stochastic regime The step of random request includes:
Random interface is recalled in offer, described to recall random interface including recalling reason dialog box;
It receives through the information for recalling the input of reason dialog box.
7. method according to claim 1 or 6, which is characterized in that receive in the subject's of stochastic regime Recalling random request further includes later:
Approval is provided and recalls interface;
Receive the approval operation that interface input is recalled by the approval.
8. according to the method described in claim 5, recalling drug in the subject of dispensing it is characterized in that, receiving The step of request further includes:
Drug interface is recalled in offer, and the drug interface of recalling includes recalling reason dialog box;
It receives through the information for recalling the input of reason dialog box.
9. the method according to claim 3 or 8, which is characterized in that receive for recalling in the subject of dispensing Further include after medication request:
Approval is provided and recalls interface;
Receive the approval operation that interface input is recalled by the approval.
10. according to the method described in claim 1, being assigned to after the random number of the subject it is characterized in that, withdrawing Further include:
The trace being deleted comprising the random number on the subject interface for have permission user.
11. according to the method described in claim 2, being assigned to after the drug number of the subject it is characterized in that, withdrawing Further include:
The trace being deleted comprising the drug number on the subject interface for have permission user.
12. according to the method described in claim 2, it is characterized in that, further including:Release the random number and the drug number The correspondence of code.
13. according to the method described in claim 2, it is characterized in that, further including:Forbid it is described recall that random request is directed to by The drug number being retracted is specified after examination person in dispensing for the first time.
14. a kind of stochastic system based on network answer, including:
Memory, for storing the instruction that can be executed by processor;
Processor, for executing described instruction to realize such as claim 1-13 any one of them methods.
15. a kind of computer storage media, is stored thereon with computer instruction, wherein when computer instruction is executed by processor When, execute such as claim 1-13 any one of them methods.
CN201711477693.3A 2017-12-29 2017-12-29 Stochastic system based on network answer and recall random method Pending CN108399938A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711477693.3A CN108399938A (en) 2017-12-29 2017-12-29 Stochastic system based on network answer and recall random method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711477693.3A CN108399938A (en) 2017-12-29 2017-12-29 Stochastic system based on network answer and recall random method

Publications (1)

Publication Number Publication Date
CN108399938A true CN108399938A (en) 2018-08-14

Family

ID=63093712

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711477693.3A Pending CN108399938A (en) 2017-12-29 2017-12-29 Stochastic system based on network answer and recall random method

Country Status (1)

Country Link
CN (1) CN108399938A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114283908A (en) * 2021-12-23 2022-04-05 康奥生物科技(天津)股份有限公司 Subject data management method and system and electronic equipment

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101520824A (en) * 2009-03-06 2009-09-02 北京迪美斯科技发展有限公司 Method, device and system for testees to randomly group in medical clinical test
CN101520822A (en) * 2009-03-06 2009-09-02 北京迪美斯科技发展有限公司 Central stochastic system applied to medical clinical test
CN103714487A (en) * 2013-12-19 2014-04-09 广东粤铁科技有限公司 Ticket system and ticket-buying and ticket-checking method thereof for rail transit
CN105678392A (en) * 2015-12-25 2016-06-15 中国民航信息网络股份有限公司 Prepaid flight seat sale system and method thereof
CN105844088A (en) * 2013-08-06 2016-08-10 中国中医科学院 Universal clinical test electronic data acquisition system and method
US20160267255A1 (en) * 2010-06-12 2016-09-15 Medidata Solutions, Inc. Distributed randomization and supply management in clinical trials

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101520824A (en) * 2009-03-06 2009-09-02 北京迪美斯科技发展有限公司 Method, device and system for testees to randomly group in medical clinical test
CN101520822A (en) * 2009-03-06 2009-09-02 北京迪美斯科技发展有限公司 Central stochastic system applied to medical clinical test
US20160267255A1 (en) * 2010-06-12 2016-09-15 Medidata Solutions, Inc. Distributed randomization and supply management in clinical trials
CN105844088A (en) * 2013-08-06 2016-08-10 中国中医科学院 Universal clinical test electronic data acquisition system and method
CN103714487A (en) * 2013-12-19 2014-04-09 广东粤铁科技有限公司 Ticket system and ticket-buying and ticket-checking method thereof for rail transit
CN105678392A (en) * 2015-12-25 2016-06-15 中国民航信息网络股份有限公司 Prepaid flight seat sale system and method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114283908A (en) * 2021-12-23 2022-04-05 康奥生物科技(天津)股份有限公司 Subject data management method and system and electronic equipment

Similar Documents

Publication Publication Date Title
CA2370283C (en) Method and apparatus for conducting linked simulation operations utilizing a computer-based system model
US10791978B2 (en) Classifying individuals using finite mixture markov modelling and test trials with accounting for item position
Goldenholz et al. Confusing placebo effect with natural history in epilepsy: a big data approach
Travers et al. Motor‐linked implicit learning in persons with autism spectrum disorders
WO2021179630A1 (en) Complications risk prediction system, method, apparatus, and device, and medium
CN109741804A (en) A kind of information extracting method, device, electronic equipment and storage medium
CN106776165A (en) Server performance method of testing and system
US20200388356A1 (en) Clinical trial system for treatment application, terminal device having treatment application mounted thereon, and treatment application program
CN106846058A (en) Method and apparatus for choosing participant
CN109637615A (en) Judgment method, device, equipment and the readable storage medium storing program for executing of abnormal medicine prescription
Gould et al. Monitoring potential adverse event rate differences using data from blinded trials: the canary in the coal mine
US20130191153A1 (en) Assessing Variation In Clinical Response Data Based On A Computational Representation Of Neural Or Psychological Processes Underlying Performance On A Brain Function Test
CN108399938A (en) Stochastic system based on network answer and recall random method
CN108597563A (en) Dynamic random group technology and system
JP6771014B2 (en) Information processing equipment, information processing methods and programs
CN107526924A (en) A kind of information collecting method and system
Barricelli et al. MANTRA: mobile anticoagulant therapy management
Samper et al. Doubts about the role of rehearsal in the irrelevant sound effect
CN115691737A (en) Clinical trial electronic data management system and management method
CN112035361B (en) Test method, device, computer equipment and storage medium of medical diagnosis model
Zhan et al. A practical response adaptive block randomization (RABR) design with analytic type I error protection
CN113971997A (en) Method and system for determining drug delivery amount in clinical trial
Strielkina et al. Model of functional behavior of healthcare Internet of Things device
Abrams Influence of category size and target set size on unconscious priming by novel words
CN109388627B (en) Database access control method and device and electronic equipment

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20180814