CN108355055A - A kind of pharmaceutical composition for treating hypertension - Google Patents
A kind of pharmaceutical composition for treating hypertension Download PDFInfo
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- CN108355055A CN108355055A CN201810421198.9A CN201810421198A CN108355055A CN 108355055 A CN108355055 A CN 108355055A CN 201810421198 A CN201810421198 A CN 201810421198A CN 108355055 A CN108355055 A CN 108355055A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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Abstract
It is to carry out prescription, the oral preparations being prepared by the common process and auxiliary material of pharmacy by matrimony vine, pueraria lobata, sealwort, fried cassia, hawthorn, celery seed/FLOS CHRYSANTHEMI ALBA from Haizhou of China for bulk pharmaceutical chemicals the invention discloses a kind of pharmaceutical composition for treating hypertension.Non-clinical statistical data shows that pharmaceutical composition of the invention has good therapeutic effect for hypertension, and total effective rate is up to 89.16%.In addition, the present invention uses integration of drinking and medicinal herbs, medicinal material without any toxicity and side effects and food materials for raw material, drug safety is high, and can take for a long time also has extraordinary health effect.
Description
Technical field
The present invention relates to a kind of pharmaceutical compositions for treating hypertension, belong to traditional Chinese medicine and field of pharmaceutical preparations.
Background technology
Hypertension（hypertension）It is a kind of common, with systemic arterial blood pressure（Systolic pressure and/or diastolic pressure）Increase
A height of main feature（The millimetres of mercury of systolic pressure >=140, the millimetres of mercury of diastolic pressure >=90）Clinical syndrome, can with the heart, brain,
The function of the organs such as kidney or the clinical syndrome of organic lesion.Hypertension is most common chronic disease and cardiovascular and cerebrovascular diseases
Most important risk factor.Current 50% cardiovascular and cerebrovascular disease is caused by hypertension.High blood pressure category Chinese medicine " dizziness " and " head
Scope bitterly ", Chinese medicine think this of its disease for imbalance of yin and yang, and disease is designated as interior raw wind, phlegm, hemostasis.By it on tcm clinical practice
It is divided into liver-yang hyperactivity, hyperactivity of yang due to yin deficiency, the deficiency of liver-yin and kidney-yin and yin-yang deficiency four card types and interior wind, blood stasis, phlegm hinders three accompanying symptoms.
Types of drugs for treating hypertension is various.Currently, having 6 classes by what WHO-ISH was recommended as first-line drug：Including
Diuretics, beta-blocker, calcium antagonist, angiotensin converting enzyme inhibitor (ACEI), Angiotensin Ⅱ receptor antagonist
（AT1）, alpha blocker.But said medicine therapy still has some shortcomings, for example, Western medicine is mostly symptomatic treatment, takes stopgap measures without controlling
This, and the state of an illness easily recurs, adverse reaction is more, be also easy to produce drug resistance, long-time service also will produce dependence and withdrawal reaction.
Studies have shown that Chinese medicine has unique advantage in the treatment of angiocardiopathy.Compared with Western medicine, traditional Chinese medicine ingredients are multiple
It is miscellaneous, integration of the curative effect often by multicomponent, too many levels, multiple target point is played, treatment myocardial ischemia disease, which has, to be treated
The features such as imitating, is active strong, side effect is low, largely improves the compliance of patient.Currently, clinically also by some
Natural drug composition is for assisting in treating hypertension and achieves certain curative effect, for example, FUFANG LUOBUMA PIAN, Niuhuang Jiangya
Piece etc., still, often constituent is complicated for similar pharmaceutical composition, and drug safety is indefinite, and production technology is complicated, production
It is of high cost, it causes control of product quality difficult, is unfavorable for keeping the stability of product quality.
Invention content
The purpose of the present invention is to provide a kind of pharmaceutical compositions for treating hypertension.
It is original that pharmaceutical composition of the present invention for treating hypertension, which is by matrimony vine, pueraria lobata, sealwort, fried cassia, hawthorn,
Expect that medicine carries out prescription compatibility, each component effect is made to generate collaboration, plays promoting qi circulation and relieving pain altogether, dissipate stasis of blood knot, clear liver and improve vision, strengthening the essence life
Blood, it is eliminating dampness and eliminating phlegm the effect of, with promote Blood vessel cleaning and adjust blood fat, blood pressure, reduce blood viscosity.
Hawthorn, sour sweet, tepor, enters spleen, stomach, Liver Channel, and it is that China is peculiar to have digestion gathered food, scattered blood stasis, taenifugal effect
Dual-purpose of drug and fruit species, have the effects that reducing blood lipid, blood pressure, cardiac stimulant, arrhythmia, main component is flavonoids and organic acid
Class compound.
Matrimony vine, it is sweet in flavor, it is mild-natured.Function：Tonifying kidney and benefiting sperm nourishes the liver to improve visual acuity, and blood-enriching tranquillizing promotes the production of body fluid to quench thirst, and moistens the lung and relieve the cough.It is modern
Studies have shown that polysaccharides can effectively reduce the content of triglycerides and cholesterol in the rat blood serum for suffer from hyperlipidemia, have
Apparent reducing blood lipid adjusts lipid metabolism function, has positive effect to prevention of cardiovascular disease.Impaired pancreas islet can be remarkably reinforced
Intracellular superoxide mutase（SOD）Activity, improve the oxidation resistance of islet cells, mitigate peroxide to cell
Damage reduces interior dialdehyde production quantity, this shows that polysaccharides has islet cells certain protective effect.Modern is come
It says, the most practical effect of matrimony vine is exactly antifatigue and reduces blood pressure.
Pueraria lobata, it is sweet in flavor, pungent, it is cool in nature.It brings down a fever with expelling pathogenic factors from muscles and skin, the effect of promoting eruption promotes the production of body fluid to quench thirst, Shengyang Zhixie.Contain pueraria lobata
The Multiple components such as element, daizeol, arachidic acid, amino acid, protein, multivitamin, organic calcium, and have invigorating the spleen protect liver, disappear
Thermal detoxification, promoting production of body fluid and benefiting qi, reducing blood lipid, hypoglycemic effect, be the current Ministry of Agriculture, the Ministry of Public Health approve edible and medicinal health products.
Sealwort, it is sweet in flavor, it is mild-natured, there is the effect of boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney-nourishing.It is main to contain Siberian solomonseal rhizome polysaccharide, steroidal soap
Glycosides composition.For the medicine-food two-purpose medicinal material that the Ministry of Public Health ratifies to use, it is antifatigue, soft that pharmacological evaluation shows that Rhizoma Polygonati extract has
Change blood vessel, reduce blood glucose and improve immunity and the effects that resisting myocardial ischemia, has good protective effect to blood pressure.
Fried cassia（It fries）, it is bitter, sweet and cool in nature, have the function of clearing away the liver-fire, wind-damp dispelling, tonifying kidney and improving eyesight etc..Fried cassia
Rich in ingredients such as Chrysophanol, rheum emodin, obtusins, has the function of decompression, antibacterial and reduce cholesterol, adjust fat.
The present invention is using hawthorn as monarch drug in a prescription, food digesting stomach fortifying, scattered stasis, reducing blood lipid, blood pressure lowering；It is with pueraria lobata, fried cassia
Ministerial drug, wherein pueraria lobata promote the production of body fluid to quench thirst, the work(of Shengyang Zhixie, and pueraria lobata has the benefits of improving brain blood cycle, to because of hypertension
The symptoms such as caused headache, dizziness, tinnitus and pain in low back and legs have preferable alleviation effect；Cassia seed is adjutant, auxiliary monarch drug in a prescription drop
Blood pressure, clears liver and improve vision at reducing blood lipid；It is to make with sealwort, matrimony vine, boosting qi and nourishing yin, strengthening the essence reinforce the kidney, clear liver and improve vision.Complete put beats the scattered stasis of blood altogether
Change tie, clear liver and improve vision, strengthening the essence green blood, it is eliminating dampness and eliminating phlegm the effect of, with promote Blood vessel cleaning and adjust blood pressure, reduction blood viscousness
Degree alleviates headache, the symptoms such as dizziness, tinnitus caused by hypertension.
The Chinese medicine composition of the present invention, each bulk pharmaceutical chemicals are matched by with following weight parts：9-13 parts of sealwort, fried cassia
7-12 parts, 6-10 parts of pueraria lobata, 10-15 parts of hawthorn, 2-6 parts of matrimony vine, 0 ~ 5 part of celery seed/FLOS CHRYSANTHEMI ALBA from Haizhou of China.
Optimum ratio：10-12 parts of sealwort, fried cassia be 8-10 parts sub-, 6-8 parts of pueraria lobata, 12-15 parts of hawthorn, 3-5 parts of matrimony vine,
2 ~ 4 parts of celery seed/FLOS CHRYSANTHEMI ALBA from Haizhou of China.
Optimum proportioning：12 parts of sealwort, 9 parts of fried cassia, 8 parts of pueraria lobata, 14 parts of hawthorn, 4 parts of matrimony vine, 3 parts of celery seed.
The present invention Chinese medicine composition, the oral preparations that can be prepared by the common process and auxiliary material of pharmacy, as tablet,
Powder, granule, soft capsule, hard capsule, oral solution, vina, distillate medicinal water, medicinal tea etc..
The effect of hypertension therapy of the present invention is illustrated below by clinical trial.
1. treatment group's drug：Sealwort medlar tea：（Pharmaceutical composition of the present invention is prepared according to the method for embodiment 1）, by sweet
Respectful hundred thatched cottages Pharmaceutical Technology Co., Ltd provides.Specification：Per packed 10g.
2. control group medication：Bezoar pill for lowering blood pressure is produced by Beijing Pharmacy stock Co., Ltd of Tongrentang（Chinese medicines quasi-word
Z11020199）, commercially available.Specification：1.6g/ balls, per 10 ball of box.
3. test method
3.1 pathology select：Chinese herbalist clinic is selected in hypertensive patient 88 altogether from November, 2014 in September, 2016, is randomly divided into
Treatment group and control group, treatment group is 48 selected, 32 ~ 70 years old age, average age（51.66±11.34）Year, wherein male 25
Example, women 23；It was found that 1.5 ~ 6.5 years hypertension time.Control group is 40 selected, 31 ~ 70 years old age, average age 52.23
± 11.67 years old, wherein male 22, women 18；It was found that 1.2 ~ 6.5 years hypertension time.Two groups of comparing differences are without conspicuousness
(P>0.05).All patients meet 1 999 years W H O Evaluation of Diagnostic Criteria of Hypertension：The m m H g of systolic pressure >=14 0, diastole
>=90 m m H g, clinical manifestation are pressed to have headache, dizzy, palpitaition, insomnia, body again weak etc..All cases exclude secondary
Property hypertension and hypertensive crisis patient.
3.2 therapy：Sealwort medlar tea is taken by treatment group, 1 bag every time, daily 2 bags, sets in boiling water in a manner of making tea,
Unlimited secondary plus water is drunk to tasteless.Continuously take two months.Control group takes Bezoar pill for lowering blood pressure, 1 ball, once a day.More than
Patient observes 3 courses for the treatment of altogether with 10 days as a treatment course.
4. case is selected in and the standard of curative effect evaluation
4.1 Western medicine diagnostic criteria：Reference《2010 Chinese hypertension prevention and control guides》It formulates：（1）Non- blood pressure measurement three times on the same day, is received
>=140 or/and diastole >=90mmHg of contracting pressure；（2）Blood pressure 140-159/90-99mmHg is 1 grade of hypertension；Blood pressure 160-179/
100-109mmHg is 2 grades of hypertension；Blood pressure >=180/ >=110mmHg is 3 grades of hypertension.Systolic pressure >=140mmHg but diastolic pressure
<90mmHg is classified as simple contraction.
4.2 tcm diagnosis standard：All equal references of selected patient《New Chinese medicine guideline of clinical investigations》[2] dialectical point
Type is：Turbid interior solidifying, 4 type of hypofunction of YANG QI in chest of liver-yang hyperactivity, the deficiency of liver-yin and kidney-yin, phlegm.
4.3 inclusion criteria：1. meeting hypertension diagnosis；2. for 1 grade, 2 grades of hypertension or simple systolic phase phase hypertension；③
Differential diagnosis in tcm is one of liver-yang hyperactivity, the deficiency of liver-yin and kidney-yin, the turbid interior solidifying, hypofunction of YANG QI in chest of phlegm；4. the age is between 30 ~ 70 years old；5. voluntarily
Sign informed consent form.
4.5 the standard of curative effect evaluation：It is effective：Hypertension clinic cardinal symptom disappears, and diastolic pressure reaches normal range (NR)；Or diastole
Though pressure does not drop to normally, 20 m m Hg or more are declined.Effectively：Hypertension clinic cardinal symptom is relieved, diastole
Drops<1 0mmHg, but have reached normal range；Or diastolic pressure relatively treats 10 ~ 19mmHg of preceding decline, but do not reach just
Normal range；Or systolic pressure relatively treats preceding decline 30mmHg.In vain：Without substantially reduced, blood pressure does not have hypertension clinic cardinal symptom
Decline or blood pressure are got higher before relatively treating.Using effective number and significant figure as total significant figure.
4.6 statistical procedures：All data are handled using SPSS1.30 statistics softwares, component count data ratio
Compared with using X2It examines, with P<0.05 has statistical significance for difference.
5. result
5.1 total effects compare：After treating three courses for the treatment of, treatment group's total effective rate is 89.16%, and control group total effective rate is
77.5%, there was no significant difference for comparison among groups（P>0.05）, it is shown in Table 1：
Treatment group and control group compare, P>0.05.Although statistical procedures curative effect no significant difference, total effective rate numerical value sheet
Invention pharmaceutical composition sealwort medlar tea is substantially better than control group drug.
5.2 two groups of pretherapy and post-treatment blood pressures compare：It is shown in Table 2：
As can be seen from Table 2, pharmaceutical composition of the present invention can effectively treat hypertension；And with existing marketed drug phase
Than under identical administering mode, the effect of pharmaceutical composition of the present invention significantly improves.Belonging to sum up, pharmaceutical composition of the present invention
Object can treat hypertension, provide a kind of new selection for clinical treatment hypertension, drug safety is high, and application prospect is good
It is good.
Specific implementation mode
The prescription of pharmaceutical composition of the present invention, preparation and dosage form are described further below by specific embodiment.
Embodiment 1：The preparation of medicinal tea
Raw material proportioning：12 parts of sealwort, 9 parts of fried cassia, 8 parts of pueraria lobata, 14 parts of hawthorn, 4 parts of matrimony vine, 3 parts of celery seed；
Preparation process：It by above-mentioned 5 taste medicinal material through pure water rinsing, 60 DEG C of drying, mixes, crushes, cross 14 mesh sieve, bag is made in packing
It makes tea agent.Specification：Per packed 10g；
Instructions of taking：It 1 bag every time, daily 2 bags, sets in boiling water in a manner of making tea, unlimited secondary plus water is drunk to tasteless.Continuously take
Two months.
Embodiment 2：The preparation of granule
Raw material proportioning：10 parts of sealwort, 8 parts of fried cassia, 6 parts of pueraria lobata, 12 parts of hawthorn, 3 parts of matrimony vine, 2 parts of celery seed；
Preparation process：Above-mentioned 6 taste medicinal material is added water to cook three times, each amount of water is 8 times of amounts of medicinal material, and decocting time 1 hour closes
And decocting liquid, filtration, it is 1.2 that filtrate, which is concentrated into relative density,（40℃）Thick paste, mixing is dried under reduced pressure（50 ~ 60 DEG C, 0.08 ~-
0.09Mpa）, it is ground into fine powder（Cross No. 5 sieves, 80 mesh）, be added dextrin, mixing, wet method be made granule to get.Specification：Every bag
Fill 5g；
Instructions of taking：1 bag every time, daily 2 bags, warm boiled water.Continuously take two months.
Embodiment 3：The preparation of capsule
Raw material proportioning：12 parts of sealwort, 10 parts of fried cassia, 8 parts of pueraria lobata, 14 parts of hawthorn, 5 parts of matrimony vine, 4 parts of celery seed；
Preparation process：Above-mentioned 6 taste medicinal material is added water to cook three times, each amount of water is 8 times of amounts of medicinal material, and decocting time 1 hour closes
And decocting liquid, filtration, it is 1.12 that filtrate, which is concentrated into relative density,（60℃）Thick paste, mixing is dried under reduced pressure（50 ~ 60 DEG C, 0.08 ~-
0.09Mpa）, it is ground into fine powder（Cross No. 5 sieves, 80 mesh）, maltodextrin, mixing is added, wet method is made granule, filling capsule,
To obtain the final product.Specification：Every 0.3g；
Instructions of taking：5 tablets each time, 2 times a day, warm boiled water.Continuously take two months.
Embodiment 4：The preparation of tablet
Raw material proportioning：9 parts of sealwort, 7 parts of fried cassia, 6 parts of pueraria lobata, 10 parts of hawthorn, 2 parts of matrimony vine；
Preparation process：Above-mentioned 5 taste medicinal material is added water to cook 2 times, each amount of water is that 12 times of medicinal material is measured, decocting time 1.5 hours,
Collecting decoction, filtration, it is 1.15 that filtrate, which is concentrated into relative density,（60℃）Thick paste, mixing is dried under reduced pressure（50 ~ 60 DEG C, 0.08
~-0.09Mpa）, it is ground into fine powder（Cross No. 4 sieves, 80 mesh）, microcrystalline cellulose, mixing is added, dry method is made particle, tabletting, i.e.,
.Specification：Every 0.5g；
Instructions of taking：3 tablets once, 2 times a day, warm boiled water.Continuously take two months.
Embodiment 5：The preparation of pill
Raw material proportioning：13 parts of sealwort, 12 parts of fried cassia, 10 parts of pueraria lobata, 15 parts of hawthorn, 6 parts of matrimony vine, 5 parts of celery seed；
Preparation process：Above-mentioned 6 taste medicinal material is added water to cook 2 times, each amount of water is that 12 times of medicinal material is measured, decocting time 1.5 hours,
Collecting decoction, filtration, it is 1.15 that filtrate, which is concentrated into relative density,（60℃）Thick paste, mixing is dried under reduced pressure（50 ~ 60 DEG C, 0.08
~-0.09Mpa）, pueraria lobata is ground into fine powder（Cross No. 7 sieves, 120 mesh）, be added above-mentioned extract powder, mixing, general ball to get.Specification：
Every 0.3g；
Instructions of taking：3 tablets each time, 2 times a day, warm boiled water.Continuously take two months.
Embodiment 6：The preparation of medicinal tea
Raw material proportioning：12 parts of sealwort, 9 parts of fried cassia, 8 parts of pueraria lobata, 7 parts of hawthorn, 4 parts of matrimony vine, 3 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China；
Preparation process：By above-mentioned 6 taste pharmaceutical decocting piece, mixes, dispenses in proportion, bag tea agent is made.Specification：Per packed 20g；
Instructions of taking：It 1 bag every time, daily 1 bag, sets in boiling water in a manner of making tea, unlimited secondary plus water is drunk to tasteless.Continuously take
Two months.
In the various embodiments described above, the proportioning of each raw material is in parts by weight.
Claims (5)
1. a kind of pharmaceutical composition for treating hypertension is by sealwort, fried cassia, pueraria lobata, hawthorn, matrimony vine, celery seed/Hang Bai
Chrysanthemum is that bulk pharmaceutical chemicals carry out prescription, the oral preparations being prepared by the common process and auxiliary material of pharmacy.
2. a kind of pharmaceutical composition for treating hypertension as described in claim 1, it is characterised in that：Each bulk pharmaceutical chemicals are by following
Parts by weight are stated to be matched：9-13 parts of sealwort, fried cassia be 7-12 parts sub-, 6-10 parts of pueraria lobata, 10-15 parts of hawthorn, 2-6 parts of matrimony vine,
0 ~ 5 part of celery seed/FLOS CHRYSANTHEMI ALBA from Haizhou of China.
3. a kind of pharmaceutical composition for treating hypertension as described in claim 1, it is characterised in that：Each bulk pharmaceutical chemicals are by following
Parts by weight are stated to be matched：10-12 parts of sealwort, fried cassia be 8-10 parts sub-, 6-8 parts of pueraria lobata, 12-15 parts of hawthorn, 3-5 parts of matrimony vine,
2 ~ 4 parts of celery seed/FLOS CHRYSANTHEMI ALBA from Haizhou of China.
4. a kind of pharmaceutical composition for treating hypertension as described in claim 1, it is characterised in that：Each bulk pharmaceutical chemicals are by following
Parts by weight are stated to be matched：12 parts of sealwort, 9 parts of fried cassia, 8 parts of pueraria lobata, 14 parts of hawthorn, 4 parts of matrimony vine, 3 parts of celery seed.
5. a kind of pharmaceutical composition for treating hypertension as described in claim 1, it is characterised in that：The oral preparations are piece
Agent, powder, granule, soft capsule, hard capsule, oral solution, vina, distillate medicinal water, medicinal tea, medicine materical crude slice agent.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111053167A (en) * | 2020-01-20 | 2020-04-24 | 颜振清 | Medicine and food homologous selenium-zinc-rich trace element three-high regulation beverage and preparation process thereof |
| CN115813871A (en) * | 2022-12-23 | 2023-03-21 | 宝利康生物科技(天津)有限公司 | Blood pressure reducing tablet candy and application method thereof |
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| CN101822749A (en) * | 2010-01-28 | 2010-09-08 | 窦啟玲 | Medicinal preparation for curing hypertension and hyperlipaemia and preparation method thereof |
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| CN101411497A (en) * | 2008-11-26 | 2009-04-22 | 河南省宛西制药股份有限公司 | Lipid-lowering pressure-reducing hypoglycemic health tea |
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| CN101912021A (en) * | 2010-09-07 | 2010-12-15 | 张玉喜 | Celery tea drink and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111053167A (en) * | 2020-01-20 | 2020-04-24 | 颜振清 | Medicine and food homologous selenium-zinc-rich trace element three-high regulation beverage and preparation process thereof |
| CN115813871A (en) * | 2022-12-23 | 2023-03-21 | 宝利康生物科技(天津)有限公司 | Blood pressure reducing tablet candy and application method thereof |
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Application publication date: 20180803 |