CN108309888A - A kind of anti-inflammation detumescence Deacne pack - Google Patents

A kind of anti-inflammation detumescence Deacne pack Download PDF

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Publication number
CN108309888A
CN108309888A CN201810352643.0A CN201810352643A CN108309888A CN 108309888 A CN108309888 A CN 108309888A CN 201810352643 A CN201810352643 A CN 201810352643A CN 108309888 A CN108309888 A CN 108309888A
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Prior art keywords
extract
trehalose
milfoil
gymnema sylvestre
inflammation detumescence
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不公告发明人
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Foshan Sanshui Jiahua Chemical Research Institute (general Partnership)
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Foshan Sanshui Jiahua Chemical Research Institute (general Partnership)
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Priority to CN201810352643.0A priority Critical patent/CN108309888A/en
Publication of CN108309888A publication Critical patent/CN108309888A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645Proteins of vegetable origin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/008Preparations for oily skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of anti-inflammation detumescence Deacne packs, include the ingredient of following mass percent:Gymnema sylvestre extract 0.1 10%, milfoil extract 0.1 8%, Herba Commelinae extract 0.1 8%, trehalose 0.2 4%, pumpkin albumen 0.2 6%.The effect of facial mask of the present invention passes through broad-spectrum antibacterial is capable of the microbial environment on balance skin surface, while also having effects that moisturizing oil-control with detumescence, analgesia and Healing to skin damage, effectively takeing good care of skin.

Description

A kind of anti-inflammation detumescence Deacne pack
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of anti-inflammation detumescence Deacne pack.
Background technology
Sebum secretion is vigorous easily to put aside dirt, especially fat-soluble organic substance and perhaps multiple-microorganism, and induces scorching Disease.Pore is coarse, is easy to cause bacterium, fungi, virus etc. that can drive straight in, and causes infection, so as to cause inflammatory reaction.It is scorching More even can occur small pox along with red and swollen, shouting pain, influence beauty again during disease.
Invention content
The technical problem to be solved in the present invention is to provide a kind of anti-inflammation detumescence Deacne packs.Facial mask of the present invention is pressed down by wide spectrum The effect of bacterium, is capable of the microbial environment on balance skin surface, while having detumescence, analgesia and Healing to skin damage, Also have effects that moisturizing oil-control, effectively takees good care of skin.
To achieve the above object, the present invention provides following scheme:
A kind of anti-inflammation detumescence Deacne pack, includes the ingredient of following mass percent:Gymnema sylvestre extract 0.1-10%, alpine yarrow Careless extract 0.1-8%, Herba Commelinae extract 0.1-8%, trehalose 0.2-4%, pumpkin albumen 0.2-6%.
Further, the anti-inflammation detumescence Deacne pack, includes the ingredient of following mass percent:Gymnema sylvestre extract 2-8%, milfoil extract 2-6%, Herba Commelinae extract 2-6%, trehalose 0.5-3%, pumpkin albumen 1-5%.
Further, the facial mask includes the ingredient of following mass percent:Gymnema sylvestre extract 5%, milfoil carry Take object 4%, Herba Commelinae extract 4%, trehalose 2%, pumpkin albumen 3%.
The present invention also provides a kind of anti-inflammation detumescence Deacne packs, further include the ingredient of following mass percent:Glycerine 2- 8%, butanediol 5-15%, glycine betaine 1-3%, Sodium Hyaluronate 0.05-0.1%, dipotassium glycyrrhizinate 0.02-0.08%, card wave Nurse 0.1-0.4%, xanthans 0.01-0.08%, EDETATE SODIUM 0.1-0.3%, methyl hydroxybenzoate 0.02-0.1%, Nipasol 0.02-0.1%, deionization surplus.
The present invention also provides a kind of preparation methods of anti-inflammation detumescence Deacne pack:
(1) by glycerine, butanediol, glycine betaine, Sodium Hyaluronate, carbomer, xanthans, EDETATE SODIUM, methyl hydroxybenzoate, hydroxyl Phenylpropyl alcohol ester, deionized water are added in agitated kettle and are heated to 80-85 DEG C, and stirring and dissolving is complete;
(2) it is cooled to 45-55 DEG C, Gymnema sylvestre extract, milfoil extract, Herba Commelinae extract, trehalose, pumpkin is added Complete, cooling discharging is extremely dissolved in seed albumen, dipotassium glycyrrhizinate, stirring.
Compared with prior art, the invention has the advantages that:
(1) present invention by Gymnema sylvestre extract, milfoil extract, Herba Commelinae extract, trehalose and pumpkin albumen into Row reasonable compatibility, scientific matching make different effective active compositions generate synergistic function, greatly increase plant component Activity.(2) present invention has effects that broad-spectrum antibacterial, is capable of the microbial environment on balance skin surface, anti-inflammatory to play Effect;Simultaneously to causing skin damage that there is detumescence, analgesia because squeezing small pox and promoting Healing;The also work(with moisturizing oil-control Effect realizes that anti-acne, long-time service can effectively take good care of skin, beautiful skin of getting well.Pumpkin albumen being capable of anti-inflammatory, adjusting office Portion's skin environment balance, collaboration trehalose can also effectively improve the holding oiliness and retentiveness of product, so that product is had excellent Water conservation oil absorption.Gymnema sylvestre extract, milfoil extract, Herba Commelinae extract synergistic effect, effective antimicrobial antiphlogistic, promoting blood circulation stop Bitterly.(3) present component is green safe, mildly non-stimulated to skin, and preparation process is simple, adapts to industrialized production.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to Routine techniques carries out.
Involved each ingredient is described as follows in facial mask of the present invention:
Gymnema sylvestre (Gymnema sylvestre (Retz.) Schult, abbreviation GS) is trailing plants Mi sections Gymnema (Gymnema R.Br.) class plant, also known as australian cowplant root or leaf, Jong-koutong, Smilax china L mainly contain saponin, terpene, flavones, polypeptide, pectin, biology The chemical compositions such as alkali, polysaccharide.Sinha etc. studies three kinds of gram positive bacterias of Gymnema sylvestre extract pair (hay bacillus, golden yellow grape Coccus and micrococcus luteus) and five kinds of gram-negative bacterias (Escherichia coli, comma bacillus, pseudomonas aeruginosa, shigella dysenteriae and Shigella) bacteriostasis, find Gymnema sylvestre extract significant bacteriostasis is all had to above 8 kinds of bacteriums;Malik etc. It was found that gymnema sylvestre water extract has anti-inflammatory effect, and when gymnema sylvestre mass fraction is 200,300 and 500mg/kg, disappear with the positive Scorching drug (bute) has similar anti-inflammatory activity.It is anti-that Diwan etc. has found that gymnema sylvestre has in inflammation model Scorching effect, the anti-inflammatory significant effect in the claw oedema of rat and peritonaeum edema model.
Milfoil, alias alpine yallow herb, alpine yarrow, centipede wormwood artemisia, Flying Centipede.Herb containing alpine yarrow element, blue sesame oil not, gum camphor and Deacetylmatricarin, aconitic acid, succinic acid, fumaric acid, ɑ-furans acid, synanthrin and Cineole.Milfoil is in China northeast, North China And the ground such as Shaanxi, Gansu are widely distributed, wild resource is abundant.Milfoil has the effect of detoxification and promoting urination, promoting blood circulation and stopping pain.It cures mainly A variety of diseases such as " acute tonsillitis pharyngalgia, dysentery, abdominalgia with intestinal abscess, puckery pain of heat gonorrhea, under humid tropics, snakebite and bugbite ".In addition, milfoil carries Take object in vitro to staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, bacterium sonnei, bacterium flexneri has height Inhibiting effect.
Dayflower is the herb of Commelianaceae Commelina dayflower.《Compendium of Materia Medica》、《The southern regions of the Yunnan Province book on Chinese herbal medicine》、《This Grass pushes away old》In it is on the books.Dayflower is cold in nature, sweet in flavor, light, return lung, stomach, small intestinl channel, with row water, heat-clearing, cool blood, removing toxic substances Effect.Takeda etc. is detached from dayflower identifies flavocommelin, duck plantar flavine;The separation such as Baek identify suberone, The compounds such as black malt lactone, cupreol.Dayflower has broad-spectrum antibacterial action, can be to anti-Staphylococcus aureus, white Color staphylococcus, eight connect coccus, streptococcus, Escherichia coli, typhoid bacillus etc., while having anti-inflammatory, analgesic activity.
Trehalose is the nonreducing sugar being made of special disaccharide molecule, and property is highly stable, can high temperature, it is high and cold, Special protective film is formed in cell surface under conditions of dry dehydration etc. is severe, is effectively protected biomolecular structure and is not broken It is bad, to the life process and biological characteristic of the body that sustains life.The moisture-keeping function of trehalose is hydroxyl, Suo Ji in glycan molecule Hydrogen bond can be formed with other polar groups with hydrone and combines a large amount of moisture, meanwhile, sugar subchain is also interweaved networking Shape plays very strong water retention in addition with the Hydrogenbond of water.
Pumpkin is also known as white melon seeds, gold melon seed, is grown in the inside of pumpkin, is the mature seed of cucurbitaceous plant pumpkin. Contain the nutritional ingredients such as abundant fat, protein, sterol and various minerals in pumpkin.With oxidation-resisting and caducity, disappear The effects that inflammation, vasodilator, adjusting local skin environmental balance.Wherein, abundant pumpkin albumen, plant are contained in pumpkin Albumen can be absorbed since amino acid classes are complete and composition ratio relatively balances, have higher nutritive value, and due to it easily It is quality raw materials, while pumpkin albumen can effectively improve product with excellent additional effects such as anti-oxidant and vasodilators Holding oiliness and retentiveness, make product have excellent water conservation oil absorption.
Embodiment 1
A kind of anti-inflammation detumescence Deacne pack, includes the ingredient of following mass percent:Gymnema sylvestre extract 0.1, milfoil carry Take object 0.1, Herba Commelinae extract 0.1, trehalose 0.2, pumpkin albumen 0.2, glycerine 2, butanediol 5, glycine betaine 1, hyalomitome Sour sodium 0.05, dipotassium glycyrrhizinate 0.02, carbomer 0.1, xanthans 0.01, EDETATE SODIUM 0.1, methyl hydroxybenzoate 0.02%, oxybenzene Propyl ester 0.02%, deionization surplus.
Embodiment 2
A kind of anti-inflammation detumescence Deacne pack, includes the ingredient of following mass percent:Gymnema sylvestre extract 10%, milfoil carry Take object 8%, Herba Commelinae extract 8%, trehalose 4%, pumpkin albumen 6%, glycerine 8%, butanediol 15%, glycine betaine 3%, Sodium Hyaluronate 0.1%, dipotassium glycyrrhizinate 0.08%, carbomer 0.4%, xanthans 0.08%, EDETATE SODIUM 0.1-0.3%, Methyl hydroxybenzoate 0.1%, Nipasol 0.1%, deionization surplus.
Embodiment 3
A kind of anti-inflammation detumescence Deacne pack, includes the ingredient of following mass percent:Gymnema sylvestre extract 5%, milfoil carry Take object 4%, Herba Commelinae extract 4%, trehalose 2%, pumpkin albumen 3%, glycerine 5%, butanediol 11%, glycine betaine 2%, Sodium Hyaluronate 0.08%, dipotassium glycyrrhizinate 0.05%, carbomer 0.25%, xanthans 0.05%, EDETATE SODIUM 0.2%, hydroxyl Benzene methyl 0.06%, Nipasol 0.06%, deionization surplus.
Embodiment 4
A kind of anti-inflammation detumescence Deacne pack, includes the ingredient of following mass percent:Gymnema sylvestre extract 2-8%, milfoil Extract 2-6%, Herba Commelinae extract 2-6%, trehalose 0.5-3%, pumpkin albumen 1-5%, glycerine 2-8%, butanediol 5-15%, glycine betaine 1-3%, Sodium Hyaluronate 0.05-0.1%, dipotassium glycyrrhizinate 0.02-0.08%, carbomer 0.1- 0.4%, xanthans 0.01-0.08%, EDETATE SODIUM 0.1-0.3%, methyl hydroxybenzoate 0.02-0.1%, Nipasol 0.02- 0.1%, deionization surplus.
Embodiment 5
A kind of anti-inflammation detumescence Deacne pack, includes the ingredient of following mass percent:Gymnema sylvestre extract 2-8%, milfoil Extract 2-6%, Herba Commelinae extract 2-6%, trehalose 0.5-3%, pumpkin albumen 1-5%, glycerine 2-8%, butanediol 5-15%, glycine betaine 1-3%, Sodium Hyaluronate 0.05-0.1%, dipotassium glycyrrhizinate 0.02-0.08%, carbomer 0.1- 0.4%, xanthans 0.01-0.08%, EDETATE SODIUM 0.1-0.3%, methyl hydroxybenzoate 0.02-0.1%, Nipasol 0.02- 0.1%, deionization surplus.
Embodiment 6
A kind of preparation method of anti-inflammation detumescence Deacne pack:(1) by glycerine, butanediol, glycine betaine, Sodium Hyaluronate, card Wave nurse, xanthans, EDETATE SODIUM, methyl hydroxybenzoate, Nipasol, deionized water are added in agitated kettle and are heated to 83 DEG C, and stirring is molten Solution is complete;(2) 45 DEG C are cooled to, Gymnema sylvestre extract, milfoil extract, Herba Commelinae extract, trehalose, pumpkin egg is added In vain, complete, cooling discharging is extremely dissolved in dipotassium glycyrrhizinate, stirring.
Embodiment 7
A kind of preparation method of anti-inflammation detumescence Deacne pack:(1) by glycerine, butanediol, glycine betaine, Sodium Hyaluronate, card Wave nurse, xanthans, EDETATE SODIUM, methyl hydroxybenzoate, Nipasol, deionized water are added in agitated kettle and are heated to 80 DEG C, and stirring is molten Solution is complete;(2) 50 DEG C are cooled to, Gymnema sylvestre extract, milfoil extract, Herba Commelinae extract, trehalose, pumpkin egg is added In vain, complete, cooling discharging is extremely dissolved in dipotassium glycyrrhizinate, stirring.
Embodiment 8
A kind of preparation method of anti-inflammation detumescence Deacne pack:(1) by glycerine, butanediol, glycine betaine, Sodium Hyaluronate, card Wave nurse, xanthans, EDETATE SODIUM, methyl hydroxybenzoate, Nipasol, deionized water are added in agitated kettle and are heated to 85 DEG C, and stirring is molten Solution is complete;(2) 55 DEG C are cooled to, Gymnema sylvestre extract, milfoil extract, Herba Commelinae extract, trehalose, pumpkin egg is added In vain, complete, cooling discharging is extremely dissolved in dipotassium glycyrrhizinate, stirring.
A kind of preparation method of anti-inflammation detumescence Deacne pack is above-described embodiment 6 in embodiment 1,2;It is a kind of in embodiment 3 The preparation method of anti-inflammation detumescence Deacne pack is above-described embodiment 7;A kind of preparation of anti-inflammation detumescence Deacne pack in embodiment 4,5 Method is above-described embodiment 8.
Comparative example 1
Compared with Example 1, Gymnema sylvestre extract is not added.
Comparative example 2
Compared with Example 1, milfoil extract is not added.
Comparative example 3
Compared with Example 1, Herba Commelinae extract is not added.
Comparative example 4
Compared with Example 1, trehalose is not added.
Comparative example 5
Compared with Example 1, pumpkin albumen is not added.
Comparative example 6
Compared with Example 1, Gymnema sylvestre extract 10.1%, milfoil extract 8.1%, Herba Commelinae extract is added 8.1%, trehalose 4.1%, pumpkin albumen 6.1%.
Efficacy validation
Human body patch test
Organize 100 volunteers according to《Cosmetics safety technical specification》The human skin patch examination of (2015 editions) records It tests, the back of subject will be pasted on low sensitization adhesive tape added with the spot of tested material examination device or forearm song is surveyed, gently being pressed with palm makes Be equably pasted on skin, continue for 24 hours.Anti-inflammation detumescence obtained by test 1-5 of the embodiment of the present invention and comparative example 1-6 is dispelled Acne facial mask is to the potential adverse reaction of human skin, and the results are shown in Table 1.
Table 1
Anti-inflammation detumescence Deacne pack made from embodiment 1-5 is nonirritant to human skin as can be seen from Table 1.
Efficacy assessments
It is random to select 1000 volunteers, each experimental group choose facial inflammatory reaction, long acne, the inclined oiliness of skin it is on probation 60 people of person (male 40 female 20), used 1 time every 1 day, is used continuously 1 month.Other any skin cares must not be used to produce in experimentation Product, and subject has been fully completed verification process, and experimental result is shown in Table 2:
2 each embodiment of table, comparative example using effect
It is moistened by 2 visible embodiment 1-5 of table, the apparent number of anti-acne effect is far above comparative example 1-6, it is seen that system of the present invention Standby facial mask can assign skin and moisten effect well, have excellent preserving moisture and protecting skin effect, improve dry skin problem, to Skin water and oil balance is maintained, effective anti-acne effect is further played.
Bacteriostasis efficacy is verified
For trying strain:Staphylococcus aureus, Escherichia coli, propionibacterium acnes
Culture medium and condition of culture:Nutrient agar (36 ± 1 DEG C of incubator 48 ± 2h of culture, for golden yellow grape Coccus, Escherichia coli culture), cooked meat medium (be used for propionibacterium acnes culture).
Test method:With reference to National Standard of the People's Republic of China GB15797-2002, " Disposable Sanitary Accessory is defended Appendix C 4 " stripping property resists (suppression) bacterium product bacteriostasis property test method " in raw standard ".
Formula:X=(A-B)/A × 100%
In formula:X --- bacteriostasis rate, %
A --- control sample averagely recycles bacterium colony;
B --- test specimen averagely recycles bacterium colony.
Bacteriostasis efficacy is evaluated:Efficacy assessments divide three-level:It is effective, effective and invalid, it as a result see the table below 3.
Table 3
Group/strain Escherichia coli Staphylococcus aureus Propionibacterium acnes
Embodiment 1 It is effective It is effective Effectively
Embodiment 2 It is effective Effectively It is effective
Embodiment 3 It is effective It is effective It is effective
Embodiment 4 It is effective Effectively It is effective
Embodiment 5 It is effective It is effective It is effective
Comparative example 1 Effectively Effectively Effectively
Comparative example 2 Effectively Effectively Effectively
Comparative example 3 Effectively Effectively Effectively
Comparative example 4 Effectively Effectively Effectively
Comparative example 5 Effectively Effectively Effectively
Comparative example 6 Effectively Effectively In vain
Known to the data analysis of table 3 Gymnema sylvestre extract in facial mask of the present invention, milfoil extract, Herba Commelinae extract, Trehalose, pumpkin albumen compounding have synergistic function, can play significant antibacterial effect, maintain microbial balance, into One step plays effective anti-inflammatory, anti-acne effect.
The present invention is described by way of example above, but the present invention is not limited to above-mentioned specific embodiment, all to be based on Any changes or modifications that the present invention is done belong to the scope of protection of present invention.

Claims (5)

1. a kind of anti-inflammation detumescence Deacne pack, which is characterized in that include the ingredient of following mass percent:Gymnema sylvestre extract 0.1-10%, milfoil extract 0.1-8%, Herba Commelinae extract 0.1-8%, trehalose 0.2-4%, pumpkin albumen 0.2- 6%.
2. anti-inflammation detumescence Deacne pack as described in claim 1, which is characterized in that include the ingredient of following mass percent: Gymnema sylvestre extract 2-8%, milfoil extract 2-6%, Herba Commelinae extract 2-6%, trehalose 0.5-3%, pumpkin albumen 1-5%.
3. facial mask as claimed in claim 2, which is characterized in that include the ingredient of following mass percent:Gymnema sylvestre extract 5%, milfoil extract 4%, Herba Commelinae extract 4%, trehalose 2%, pumpkin albumen 3%.
4. anti-inflammation detumescence Deacne pack as described in any one of claims 1-3, which is characterized in that further include following quality percentage The ingredient of ratio:Glycerine 2-8%, butanediol 5-15%, glycine betaine 1-3%, Sodium Hyaluronate 0.05-0.1%, dipotassium glycyrrhizinate 0.02-0.08%, carbomer 0.1-0.4%, xanthans 0.01-0.08%, EDETATE SODIUM 0.1-0.3%, methyl hydroxybenzoate 0.02- 0.1%, Nipasol 0.02-0.1%, deionization surplus.
5. a kind of preparation method of the anti-inflammation detumescence Deacne pack as described in claim any one of 1-4, which is characterized in that including with Lower step:
(1) by glycerine, butanediol, glycine betaine, Sodium Hyaluronate, carbomer, xanthans, EDETATE SODIUM, methyl hydroxybenzoate, oxybenzene third Ester, deionized water are added in agitated kettle and are heated to 80-85 DEG C, and stirring and dissolving is complete;
(2) it is cooled to 45-55 DEG C, Gymnema sylvestre extract, milfoil extract, Herba Commelinae extract, trehalose, pumpkin egg is added In vain, complete, cooling discharging is extremely dissolved in dipotassium glycyrrhizinate, stirring.
CN201810352643.0A 2018-04-18 2018-04-18 A kind of anti-inflammation detumescence Deacne pack Withdrawn CN108309888A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112933022A (en) * 2021-04-16 2021-06-11 河南董欣生物科技有限公司 Composition for controlling oil and activating skin of face, preparation method and application
CN116889539A (en) * 2023-05-05 2023-10-17 天地慈(东莞)生物科技有限公司 Composition for relieving and resisting allergy, and preparation method and application thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112933022A (en) * 2021-04-16 2021-06-11 河南董欣生物科技有限公司 Composition for controlling oil and activating skin of face, preparation method and application
CN116889539A (en) * 2023-05-05 2023-10-17 天地慈(东莞)生物科技有限公司 Composition for relieving and resisting allergy, and preparation method and application thereof
CN116889539B (en) * 2023-05-05 2024-02-09 天地慈(东莞)生物科技有限公司 Composition for relieving and resisting allergy, and preparation method and application thereof

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