CN108303556B - Medical intelligent biochemical detection system - Google Patents
Medical intelligent biochemical detection system Download PDFInfo
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- CN108303556B CN108303556B CN201810021069.0A CN201810021069A CN108303556B CN 108303556 B CN108303556 B CN 108303556B CN 201810021069 A CN201810021069 A CN 201810021069A CN 108303556 B CN108303556 B CN 108303556B
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- label
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
Abstract
The invention discloses a medical intelligent biochemical detection system, which comprises a base (1), a turntable (6), a liquid injection device, a cleaning device (7), a detection device (5) and a manipulator (9); the turntable, the liquid injection device, the cleaning device, the detection device and the manipulator are all arranged on the base; the liquid injection device, the cleaning device and the detection device are arranged around the turntable; the turntable is provided with a plurality of reaction tube accommodating holes (4); the manipulator is used for moving the reaction tube into the reaction tube accommodating hole and moving the reaction tube in the reaction tube accommodating hole out of the turntable; the liquid injection device is used for injecting a reagent into the reaction tube positioned in the reaction tube accommodating hole; the cleaning device is used for cleaning the reaction tube in the reaction tube accommodating hole; the detection device is used for detecting liquid in the reaction tube after the reagent is added, and before the reagent is added, the reaction tube is provided with sample liquid. The medical intelligent biochemical detection system is high in integration level and rich in functions.
Description
Technical Field
The invention relates to a medical intelligent biochemical detection system.
Background
The existing biochemical detection system is generally arranged in a hospital or a laboratory and is not convenient to move.
In addition, the existing biochemical detection system has a plurality of processes which can not realize automation, for example, the pasting of labels on the reaction tubes needs to be finished manually;
therefore, there is a need to design a new medical intelligent biochemical detection system.
Disclosure of Invention
The invention aims to provide a medical intelligent biochemical detection system which is high in integration level and rich in functions.
The technical solution of the invention is as follows:
a medical intelligent biochemical detection system is characterized by comprising a base (1), a turntable (6), a liquid injection device, a cleaning device (7), a detection device (5) and a manipulator (9);
the turntable, the liquid injection device, the cleaning device, the detection device and the manipulator are all arranged on the base;
the liquid injection device, the cleaning device and the detection device are arranged around the turntable;
the turntable is provided with a plurality of reaction tube accommodating holes (4); the reaction tube accommodating holes are uniformly distributed along the circumferential direction of the turntable;
the manipulator is used for moving the reaction tube into the reaction tube accommodating hole and moving the reaction tube in the reaction tube accommodating hole out of the turntable;
the liquid injection device is used for injecting a reagent into the reaction tube positioned in the reaction tube accommodating hole;
the cleaning device is used for cleaning the reaction tube in the reaction tube accommodating hole;
the detection device is used for detecting liquid in the reaction tube after the reagent is added, and before the reagent is added, the reaction tube is provided with sample liquid.
A reaction tube placement array (10) consisting of a plurality of reaction tube accommodating holes is arranged on the base. 3 x 5 array. Namely three-row five-column array, the manipulator firstly places the reaction tube with the label on the reaction tube placing position array, then adds various samples into the reaction tube, and then places the reaction tube with the samples in the reaction receiving hole in the turntable. After the reaction tube is detected and cleaned, the cleaned reaction tube is moved out to the reaction tube placing position array by the manipulator for storage.
The liquid injection device comprises a first liquid injection device (2) and a second liquid injection device (3).
6 reaction tube accommodating holes are arranged on the turntable; be equipped with 6 stations around the carousel, be respectively in proper order: a starting position (12), a first liquid injection level, a second liquid injection level, a detection position, a cleaning position and a reaction tube removing position (8);
the 6 stations are circumferentially and uniformly arranged; i.e. adjacent 2 are separated by 60 deg., 60 deg. referring to the central angle relative to the centre of the turntable.
The starting position is used for placing the reaction tube containing the sample liquid into the reaction tube containing hole on the turntable by the manipulator;
the first liquid injection level and the second liquid injection level are respectively provided with a first liquid injection device and a second liquid injection device which are respectively used for injecting a first reagent and a second reagent into the reaction tube;
a detection device is arranged at the detection position;
the reaction tube removing position is used for the manipulator to remove the reaction tube from the turntable. The manipulator can be 2, one for removing the reaction tube and one for placing the reaction tube.
The manipulator is an XYZ three-axis manipulator. Three-axis manipulators are a mature prior art.
The reaction tube is provided with a label, and the detection device is provided with a scanning device for scanning the label.
The detection device is provided with a communication module for transmitting detection data and label data. The wireless transmission device comprises a wired transmission module and a wireless transmission module; the wired transmission module is used for transmitting to an upper computer, and the wireless transmission module can enable a WiFi module or a Bluetooth module or a remote transmission module to be directly transmitted to a server (cloud), for example, the remote transmission module is GPRS, 3G, 4G or 5G transmission module.
The medical intelligent biochemical detection system is also connected with a reaction tube label printing, conveying and pasting system.
The medical intelligent biochemical detection system is arranged on a battery-driven automobile, and a wireless charging circuit for charging the battery is arranged on the automobile.
The intelligent biochemical detection system also comprises a wireless charging device for charging the automobile;
the wireless charging device comprises a supporting platform arranged in a recess (201) and a transmitting coil (214) arranged on the supporting platform; the supporting platform comprises a bottom layer movable platform (202), an upper layer movable platform (216) and a lifting mechanism for connecting the bottom layer movable platform and the upper layer movable platform; a longitudinal translation mechanism is arranged on the bottom layer movable platform; the upper layer movable platform is provided with a transverse translation mechanism. The lifting mechanism is a cylinder type lifting mechanism or a scissor type lifting mechanism (215). The cylinder type lifting mechanism is a push rod type driving mechanism, such as a pneumatic cylinder or a hydraulic cylinder. The longitudinal translation mechanism comprises a guide rail (205) arranged at the bottom of the concave part and a first rack rail (206); the number of the guide rails is 2; the rack rail is one, and the rack rail and the guide rail are arranged in parallel; a plurality of travelling wheels (209) capable of rolling on the guide rails are arranged at the bottom of the bottom layer movable platform; the number of the walking wheels is 4, and one side of each walking wheel is 2;
the front end of the bottom layer movable platform is provided with a first motor (203); a rotating shaft of the first motor is provided with a gear (207), and the gear is meshed with the first rack rail; when the first motor rotates, the bottom layer movable platform can be driven to longitudinally (front and back) translate along the first rack rail. The transverse translation mechanism comprises a second rack rail (211) and a second motor; the second rack rail is transversely arranged, and the left end or the right end of the upper movable platform of the second motor is arranged; a gear meshed with the second rack rail is arranged on a rotating shaft of the second motor, and when the second motor rotates, the upper movable platform can be driven to transversely (leftwards and rightwards) translate along the second rack rail; coded discs (208) are arranged on the rotating shafts of the first motor and the second motor; the code wheel is used for detecting the number of turns of the motor rotation, so that the displacement of the platform in advancing can be converted. An electric movable cover plate (219) is arranged at the opening of the concave part; the electric driving means motor driving, or electric signal control hydraulic cylinder or air cylinder driving; the number of the movable cover plates is 2, a push rod for driving the movable cover plates is arranged in the concave part, and the upper ends of the push rods are connected with the ground of the movable cover plates; an anti-pressing mechanism (210) is also arranged at the opening of the depressed part, and when the movable cover plate is unfolded, the anti-pressing mechanism can support the movable cover plate; the pressure-proof mechanism is in a square frame shape; stainless steel or cast iron is adopted; the wireless charging system also comprises a control unit, wherein the control unit comprises an MCU, and the transverse translation mechanism and the longitudinal translation mechanism are controlled by the MCU; the MCU is also connected with a communication module. The limit switch and the code disc output signals to the MCU; the first motor and the second motor are both stepping motors; the first rack rail is positioned between the 2 guide rails; the rear end of the bottom layer movable platform is provided with a limit switch (204); the front end of the motor is provided with a limit switch (204); the bottom layer movable platform is provided with a lead with a connecting plug (213); the wire is used for connecting and acquiring mains supply so as to supply power to the transmitting coil; the bottom layer movable platform is also provided with an MCU and a single-phase bridge type rectification and inversion circuit; the single-phase bridge type rectification and inversion circuit comprises a rectifier bridge and an inverter bridge, wherein the rectifier bridge adopts 4 power diodes, the inverter adopts 4 IGBTs, the connection mode is the existing mature technology, and the G pole of the IGBT is controlled by the pulse sent by the MCU. The input side of the rectifier bridge is connected with the commercial power, and the output side of the rectifier bridge is connected with the transmitting coil through the inverter; the rectifier bridge is used for changing alternating current into direct current, and the inverter is used for changing the direct current into alternating current with different frequencies.
Has the advantages that:
the medical intelligent biochemical detection system has the following characteristics:
(1) the flow detection device adopting the turntable has the advantages that 6 stations sequentially and circularly act, the detection efficiency is high, and the automation degree is high.
(2) The label paper automatic pasting machine has the advantages that the label paper conveying, printing and pasting module is unique, automatic pasting of label paper is achieved, manual intervention is not needed, and labor cost is saved.
(3) The whole detection system can be arranged on a vehicle-mounted platform, is convenient to move and provides medical detection service for remote areas.
(4) The wireless charging module is provided, clean energy is used, the environment-friendly characteristic is achieved, and the development trend is met.
(5) The overcurrent protection module is arranged, so that stable operation of the electrical equipment is protected conveniently, and damage caused by overcurrent is avoided.
In a word, the medical intelligent biochemical detection system has rich functions and high integration level, and is easy to popularize and implement.
Drawings
FIG. 1 is a schematic diagram of the general structure of an intelligent biochemical detection system;
FIG. 2 is a schematic view of a label sheet transport and printing apparatus;
FIG. 3 is a schematic view of the transfer of the label paper from the first suction cup to the second suction cup;
FIG. 4 is a schematic view of label sheet transport;
FIG. 5 is a schematic structural view of an integrated stirring, liquid injection and liquid extraction device;
FIG. 6 is a schematic view of the construction of the roller mechanism (label paper not shown);
fig. 7 is a schematic view of the structure of the roller mechanism (a state diagram where the label paper is located at the roller mechanism);
FIG. 8 is a schematic view showing the construction of the skin rolling mechanism (a state in which a reaction tube is sandwiched by pneumatic fingers and placed on a label paper);
FIG. 9 is a schematic view of the structure of the rolling mechanism (a state diagram after the reaction tube is dropped);
FIG. 10 is an electrical schematic block diagram of a wireless charging system for an automobile;
fig. 11 is a schematic view (side view) of the general structure of the wireless charging system for the automobile;
fig. 12 is a schematic general structural diagram (top view) of a wireless charging system for an automobile;
FIG. 13 is a schematic view of the cover plate when closed;
FIG. 14 is a schematic view of the cover plate when raised;
FIG. 15 is a schematic structural view of a press-proof frame;
FIG. 16 is a schematic diagram of a dimming circuit;
fig. 17 is a schematic diagram of a constant current charging;
FIG. 18 is a circuit diagram of a current detection and relay control for a turntable motor;
fig. 19 is a schematic diagram of an adjustable amplification amplifier.
Description of reference numerals: 1-a base, 2-a first liquid injection device, 3-a second liquid injection device, 4-a reaction tube accommodating hole, 5-a detection device, 6-a turntable, 7-a cleaning device, 8-a reaction tube removing position, 9-a manipulator, 10-a reaction tube placing position array, 11-a manipulator supporting platform, and 12-a starting position; 13-reaction tube.
21-pneumatic finger, 221-roller, 222-pneumatic chuck, 22-first roller, 23-second roller, and 24-label paper pallet. 25-label paper transfer module, 26-linear guide.
30-a label tape spool, 31-a label tape, 32-a first transfer roller, 33-a first nip roller, 34-a print head, 35-a second nip roller, 36-a rotation mechanism, 37-a first suction cup, 38-label paper, 39-a second transfer roller, 40-a rewind roll, 41-a print support table, 42-a slide rail, 43-a second suction cup.
50-a scaffold; 51-needle head, 52-eccentric wheel, 53-needle head seat, 54-motor, 55-lifting cylinder, 56-liquid injection tube and 57-liquid extraction tube.
201-a concave part, 202-a bottom movable platform, 203-a first motor, 204-a limit switch, 205-a guide rail, 206-a first rack rail, 207-a second driving gear, 208-a coded disc, 209-a walking wheel, 210-a lifting platform, 211-a second rack rail, 212-a lead, 213-a power-on plug, 214-a transmitting coil, 215-a scissor type lifting mechanism, 216-an upper movable platform, 217-a push rod, 218-a pressure-proof frame and 219-a movable cover plate.
Detailed Description
The invention will be described in further detail below with reference to the following figures and specific examples:
example 1: referring to fig. 1-9, the detection system, detection method, reaction tube label printing, transferring and pasting system and method are described in detail as follows:
(I): the medical intelligent biochemical detection system is characterized by comprising a base 1, a turntable 6, a liquid injection device, a cleaning device 7, a detection device 5 and a manipulator 9;
the turntable, the liquid injection device, the cleaning device, the detection device and the manipulator are all arranged on the base;
the liquid injection device, the cleaning device and the detection device are arranged around the turntable;
the turntable is provided with a plurality of reaction tube accommodating holes 4; the reaction tube accommodating holes are uniformly distributed along the circumferential direction of the turntable;
the manipulator is used for moving the reaction tube into the reaction tube accommodating hole and moving the reaction tube in the reaction tube accommodating hole out of the turntable;
the liquid injection device is used for injecting a reagent into the reaction tube positioned in the reaction tube accommodating hole;
the cleaning device is used for cleaning the reaction tube in the reaction tube accommodating hole;
the detection device is used for detecting liquid in the reaction tube after the reagent is added, and before the reagent is added, the reaction tube is provided with sample liquid.
A reaction tube placement array 10 composed of a plurality of reaction tube accommodation holes is provided on the base. 3 x 5 array. Namely three-row five-column array, the manipulator firstly places the reaction tube with the label on the reaction tube placing position array, then adds various samples into the reaction tube, and then places the reaction tube with the samples in the reaction receiving hole in the turntable. After the reaction tube is detected and cleaned, the cleaned reaction tube is moved out to the reaction tube placing position array by the manipulator for storage.
The liquid injection device comprises a first liquid injection device 2 and a second liquid injection device 3.
6 reaction tube accommodating holes are arranged on the turntable; be equipped with 6 stations around the carousel, be respectively in proper order: a starting position 12, a first liquid injection level, a second liquid injection level, a detection position, a cleaning position and a reaction tube removing position 8;
the 6 stations are circumferentially and uniformly arranged; i.e. adjacent 2 are separated by 60 deg., 60 deg. referring to the central angle relative to the centre of the turntable.
The starting position is used for placing the reaction tube containing the sample liquid into the reaction tube containing hole on the turntable by the manipulator;
the first liquid injection level and the second liquid injection level are respectively provided with a first liquid injection device and a second liquid injection device which are respectively used for injecting a first reagent and a second reagent into the reaction tube;
a detection device is arranged at the detection position;
the reaction tube removing position is used for the manipulator to remove the reaction tube from the turntable. The manipulator can be 2, one for removing the reaction tube and one for placing the reaction tube.
The manipulator is an XYZ three-axis manipulator. Three-axis manipulators are a mature prior art.
The reaction tube is provided with a label, and the detection device is provided with a scanning device for scanning the label.
The detection device is provided with a communication module for transmitting detection data and label data. The wireless transmission device comprises a wired transmission module and a wireless transmission module; the wired transmission module is used for transmitting to an upper computer, and the wireless transmission module can enable a WiFi module or a Bluetooth module or a remote transmission module to be directly transmitted to a server (cloud), for example, the remote transmission module is GPRS, 3G, 4G or 5G transmission module.
The medical intelligent biochemical detection system is also connected with a reaction tube label printing, conveying and pasting system.
The medical intelligent biochemical detection system is arranged on a battery-driven automobile, and a wireless charging circuit for charging the battery is arranged on the automobile.
The intelligent biochemical detection system also comprises a wireless charging device for charging the automobile;
the wireless charging device comprises a supporting platform arranged in the recess 201 and a transmitting coil 214 arranged on the supporting platform; the supporting platform comprises a bottom layer movable platform 202, an upper layer movable platform 216 and a lifting mechanism for connecting the bottom layer movable platform and the upper layer movable platform; a longitudinal translation mechanism is arranged on the bottom layer movable platform; the upper layer movable platform is provided with a transverse translation mechanism. The lifting mechanism is a cylinder type lifting mechanism or a scissor type lifting mechanism 215. The cylinder type lifting mechanism is a push rod type driving mechanism, such as a pneumatic cylinder or a hydraulic cylinder. The longitudinal translation mechanism comprises a guide rail 205 and a first rack rail 206 arranged at the bottom of the recess; the number of the guide rails is 2; the rack rail is one, and the rack rail and the guide rail are arranged in parallel; a plurality of travelling wheels 209 capable of rolling on the guide rails are arranged at the bottom of the bottom layer movable platform; the number of the walking wheels is 4, and one side of each walking wheel is 2;
the front end of the bottom layer movable platform is provided with a first motor 203; the gear (207) is arranged on the rotating shaft of the first motor, the gear is meshed with the first rack rail, when the first motor rotates, the bottom layer movable platform can be driven to longitudinally (front and back) translate along the first rack rail, the transverse translation mechanism comprises a second rack rail 211 and a second motor, the second rack rail is transversely arranged, the left end or the right end of the upper layer movable platform of the second motor is arranged, the gear meshed with the second rack rail is arranged on the rotating shaft of the second motor, when the second motor rotates, the upper layer movable platform can be driven to transversely (left and right) translate along the second rack rail, the code wheels 208 are arranged on the rotating shafts of the first motor and the second motor, the code wheels are used for detecting the number of turns of the motor rotation, and therefore the number of turns of the motor can be converted into the displacement of the platform, an electric movable cover plate 219 is arranged at the opening of the concave part, the electric motor is used for driving, or an electric signal control hydraulic cylinder or air cylinder is used for driving, the movable cover plate is 2, a push rod for driving the movable cover plate is arranged in the concave part, and the upper end of the push rod is connected with the ground of the movable cover plate; the opening of the concave part is also provided with a pressure prevention machine (210), the pressure prevention mechanism can support the movable cover plate when the movable cover plate is unfolded, the pressure prevention mechanism is in a square frame shape and made of stainless steel or cast iron, the wireless charging system further comprises a control unit, the control unit comprises an MCU, a transverse translation mechanism and a longitudinal translation mechanism are controlled by the MCU, the MCU is also connected with a communication module, a limit switch and a code disc output signal to the MCU, the first motor and the second motor are both stepping motors, a first rack rail is positioned between 2 guide rails, the rear end of the bottom layer movable platform is provided with a limit switch (204), the front end of the motor is provided with the limit switch 204, the bottom layer movable platform is provided with a lead with a connecting plug 213, the lead is used for connecting and obtaining commercial power so as to supply power for a transmitting coil, the MCU and a single-phase bridge type rectifying and inverting circuit are also arranged on the bottom layer movable platform, the single-phase bridge type rectifying and inverting circuit comprises a rectifying bridge and an inverting bridge, the rectifier bridge adopts 4 power diodes, the inverter adopts 4 IGBT, the connection mode is the prior mature technology, the G pole of the IGBT is controlled by the pulse sent by the MCU. The input side of the rectifier bridge is connected with the commercial power, and the output side of the rectifier bridge is connected with the transmitting coil through the inverter; the rectifier bridge is used for changing alternating current into direct current, and the inverter is used for changing the direct current into alternating current with different frequencies.
(I): an intelligent automatic biochemical detection method comprises the following steps:
step 1: loading a reaction tube on a turntable;
placing the reaction tube containing the sample into the reaction tube containing hole on the turntable by using a manipulator;
step 2: injecting a first reagent into the reaction tube and stirring;
and 4, step 4: a detection step;
performing photoelectric detection on the liquid in the reaction tube added with the first reagent and the second reagent by using a detection device; this step is well established in the art.
And step 5, cleaning (liquid pumping, cleaning liquid injection and liquid pumping).
Extracting liquid from the detected reaction tube, injecting cleaning liquid, stirring, and extracting the liquid after stirring; the injection of the cleaning liquid and the liquid extraction can be repeated for a plurality of times;
step 6: removing the reaction tube;
the cleaned reaction tubes are removed from the carousel by a robot.
The steps 1-6 are pipelined parallel steps.
Steps 1-6 are carried out at the following 6 stations, respectively: the device comprises a starting position, a first liquid injection level, a second liquid injection level, a detection position, a cleaning position and a reaction tube removing position.
And the liquid injection, stirring and cleaning are carried out by adopting an integrated stirring, liquid injection and liquid extraction device.
The integrated stirring, liquid injection and liquid extraction device comprises a bracket 50, a lifting needle seat 53, a lifting cylinder 55, a motor 54 and a needle 51;
the support is vertically arranged, a guide groove which can facilitate lifting of the needle head seat is arranged on the support, the lifting cylinder is arranged on the support, the lower end of the lifting cylinder is connected with the needle head seat, and the lifting cylinder can drive the needle head seat to lift; the needle head seat is provided with an eccentric wheel 52 and a motor 54, and when the motor drives the eccentric wheel to rotate and the needle head seat descends to the lowest position, the needle head performs stirring action; the needle head seat is provided with a liquid injection pipe 56 and a liquid pumping pipe 57; the needle head is connected with the reagent container through the liquid injection pipe; the liquid injection pipe is provided with a valve and a (micro) liquid injection pump; the needle head is also connected with a waste liquid collecting container through a liquid pumping pipe, and a (miniature) liquid pumping pump is arranged on the liquid pumping pipe.
After the needle seat is lifted by the air cylinder, the needle is separated from the reaction tube, no action is executed, after the needle seat is lowered to the lowest position by the air cylinder, the needle extends into the reaction tube, at the moment, if the motor is started, the stirring function is executed, at the moment, if the liquid injection pump is started, the liquid injection function (such as injection of a first reagent, injection of a second reagent and cleaning liquid such as clean water) is executed, and if the liquid discharge pump is started, liquid in the reaction tube is beaten out. The whole process of injecting cleaning liquid, stirring and discharging waste liquid is cleaning.
Automatic biochemical detection is implemented by adopting a medical intelligent biochemical detection system.
Label paper is adhered to the reaction tube.
And the detection result is transmitted to an upper computer or a data collection platform (such as a server) through a communication module.
The detection process is executed on the electric vehicle platform; and charging the lithium battery in the electric automobile platform by the wireless charging device.
(III) a reaction tube label printing, conveying and pasting system, which comprises a label belt conveying device, a label printing device and a label pasting device;
the label tape transfer means includes a label tape reel 30, a first transfer roller 32, a first nip roller 33, a second nip roller 35, a second transfer roller 39, and a recovery roll 40;
a label tape 31 is arranged on the label tape reel; a plurality of label paper 38 are stuck on the label belt at equal intervals;
the label tape is led out from the label tape disc and then sequentially passes through the first transmission roller, the first flattening roller, the second flattening roller and the second transmission roller to reach a rewinding roller;
the first conducting roller and the second conducting roller are used for changing the conducting direction of the label tape;
the first flattening roller and the second flattening roller are used for flattening the label tape to be horizontal, so that the label printing device can print on the label paper conveniently; the first flattening roll and the second flattening roll are both double rolls (namely, an upper roll and a lower roll are 2, the roll surfaces are tangent, and conduction is smooth).
A label printing device is provided between the first nip roller and the second nip roller, the label printing device including a print head 34 and a print support table 41; the printing head is positioned above the label tape, and the printing support platform is positioned below the printing head and the label tape;
the label pasting device is used for pasting the printed label paper on the outer wall of the reaction tube.
The label pasting device comprises a label paper conveying device and a leather rolling device;
the label paper conveying device comprises a first suction cup 37, a rotating mechanism 36 for driving the first suction cup to rotate, a slide rail 42 and a second suction cup 43 capable of translating along the slide rail; the first sucking disc is positioned above the second transfer roller, and can suck up the label paper on the label belt (suck the side without glue) and rotate the label paper by 180 degrees in a vertical plane under the action of the rotating mechanism; the sucker rotates from the downward direction to the upward direction;
the second sucker can suck the label paper from the first sucker and move to the leather rolling device along the slide rail; (the side with the glue is absorbed, the side with the glue only has glue at two ends, and no glue is arranged in the middle, so that the label paper can not stick to the second sucking disc when the second sucking disc is loosened).
The leather rolling device comprises a pneumatic finger 21 and 2 leather rolling rollers;
the pneumatic fingers are provided with pneumatic chucks 222 for clamping the reaction tubes;
the 2 leather rolling rollers are all horizontally arranged, and the 2 leather rolling rollers are positioned below the pneumatic finger; the 2 leather roller rollers are used for supporting the label paper 6 and the reaction tube 13 when the label paper is pasted, and are also used for driving the label paper roll to be pasted on the reaction tube through rotation; when 2 leather-covered rollers rotate, the rotating directions of the 2 leather-covered rollers are the same.
A label paper transfer module (i.e., label paper transfer device) is located between the pneumatic fingers and the 2 stitching rollers, and the label paper transfer module is used to move the label paper onto the 2 stitching rollers.
The bottom of the pneumatic finger is provided with at least 1 roller 221.
Two sides of the bottom of the pneumatic finger are respectively provided with 1 group of rollers 221, and each group of rollers comprises 1 or 2 rollers.
One of the 2 rollers can be moved laterally away from the other.
The reaction tube label printing, conveying and pasting system can be in butt joint with the medical intelligent biochemical detection system, and provides the reaction tube pasted with the label paper for the medical intelligent biochemical detection system.
(IV) the reaction tube label printing, transmitting and pasting method comprises the following steps:
step a: a printing step:
printing label paper on the label tape;
step b: and (3) stripping the label paper:
peeling the label paper from the label tape based on the first suction cup;
step c: rotating the label paper:
rotating the first suction cup based on the rotating mechanism;
step D: transferring the label paper:
transferring the label paper from the first suction disc to the second suction disc based on the second suction disc;
e, conveying label paper:
conveying the label paper to 2 leather rollers by a label paper conveying device by utilizing a geothermal sucking disc;
step F: label sticking paper
The reaction tube was moved to the label paper, and 2 peeling rollers were driven so that the label paper was adhered to the reaction tube.
In the wireless charging device, the pressure prevention mechanism is in a square frame shape. Stainless steel or cast iron is adopted, and the strength is high.
The wireless charging system for the automobile further comprises a control unit, wherein the control unit comprises an MCU, and the transverse translation mechanism and the longitudinal translation mechanism are controlled by the MCU; the MCU is also connected with a communication module.
The wireless charging system of the automobile is arranged on the parking space, an electric control parking space lock controlled by the MCU is also arranged on the wireless charging system of the automobile, and the wireless charging system of the automobile is combined with the shared parking space; the mobile cover plate is provided with an identification code used for interacting with the mobile phone, the identification code is a two-dimensional code or a bar code or a character string, and the intelligent mobile phone can be associated with the parking spot lock and the parking spot by scanning the code or inputting the character string; and the charging data is fed back to the mobile phone, so that the parking and charging are jointly charged.
The communication module is used for being connected with a remote server and also used for being communicated with an automobile based on Bluetooth or wifi or being controlled by a mobile phone (such as a mobile phone APP).
The first motor and the second motor are both stepping motors.
The rear end of the bottom layer movable platform is provided with a limit switch 204; the front end of the motor is provided with a limit switch 204. The limit switch acts to indicate that the front or the rear is in place, and the motor stops rotating, so that the safe operation of the whole equipment is guaranteed.
The bottom layer movable platform is also provided with an MCU and a single-phase bridge type rectification and inversion circuit; the inverter is used for converting direct current into alternating current with different frequencies, and the frequency is changed to improve charging efficiency.
The display screen is arranged in the concave part, is connected with the MCU and is used for field debugging and displaying field state data in real time.
And the automobile end is provided with a constant-current charging circuit for efficiently charging the lithium battery.
An inductor for inducing the automobile above is arranged at the opening of the concave part, such as an ultrasonic or photoelectric sensor; and the automatic charging is realized.
The charging system also comprises a brightness adjusting circuit for adjusting the brightness of the display screen (the display screen is positioned in the cab of the vehicle-mounted platform); the brightness adjusting circuit comprises an MCU, an LED lamp string, a triode, a potentiometer Rx and an A/D converter; the triode is an NPN type triode; a knob switch is arranged above a fixing frame of the display screen and is coaxially connected with the potentiometer Rx;
the potentiometer Rx and the first resistor R1 are connected in series to form a voltage division branch, one end of the voltage division branch is connected with the positive electrode Vcc of the power supply, and the other end of the voltage division branch is grounded; the connection point of the potentiometer Rx and the first resistor R1 is connected with the input end of the A/D converter; the output end of the A/D converter is connected with the data input port of the MCU;
the LED lamp string comprises a plurality of LED lamps which are connected in series; the anode of the LED lamp string is connected with the anode Vcc of the power supply; the negative electrode of the LED lamp string is connected with the C electrode of the triode, and the E electrode of the triode is grounded through a second resistor R2; the B pole of the triode is connected with the output end of the MCU. The power supply positive pole Vcc is 5V, and the A/D converter is an 8-bit serial output type converter.
The constant-current charging circuit comprises a constant-voltage driving chip and a current feedback circuit;
(1) the voltage output end of the constant voltage driving chip is a positive output end VOUT + of the constant current charging circuit; the negative output end of the constant voltage driving chip is grounded;
the constant voltage driving chip is powered by a direct current voltage power supply end VIN + and VIN-;
(2) the current feedback circuit comprises resistors R1, R2 and R5 and a reference voltage end VREF +;
the reference voltage end VREF + is grounded through resistors R1, R2 and R5 which are sequentially connected in series;
the connecting point of the resistor R5 and the resistor R2 is a negative output end VOUT < - >;
the connection point of the resistors R1 and R2 is connected with the feedback terminal FB of the constant voltage driving chip.
The constant current charging circuit also comprises a voltage feedback circuit;
the voltage feedback circuit comprises resistors R3 and R4 and a diode D1;
the resistors R3 and R4 are connected in series and then connected between the positive output end VOUT + of the constant current charging circuit and the ground; the connection point of the resistors R3 and R4 is connected with the anode of the diode D1; the cathode of the diode D1 is connected to the feedback terminal FB of the constant voltage driving chip.
Description of the working principle:
the stable reference power supply is used as a reference voltage, and the voltage which is equal to the voltage FB is obtained by dividing the voltage by R1, R2 and R5, so that the internal PWM of the DCDC IC is adjusted by the voltage FB to control the magnitude of the output current. For example, when the output current becomes larger, the voltage across the sampling resistor R5 will increase, and since VRFE + is a fixed value, the FB voltage becomes larger, FB becomes larger, the duty cycle will decrease, and the output current decreases, thereby completing a complete feedback to achieve the purpose of stabilizing the current output.
(1) Referring to fig. 18 to 19, the current detection and relay control circuit (also referred to as an overcurrent detection and protection circuit) of the electric device (turntable driving motor) is described as follows:
the working principle is as follows: the current transformer generates mutual inductance current by inserting a field alternating current wire into the current transformer (or a coil), the larger the field power consumption is, the larger the mutual inductance current is, the smaller the field power consumption is, and the smaller the mutual inductance current is, so that a signal waveform can be output by using a voltage comparator, and a Main Controller (MCU) can acquire field current size information by self-contained AD acquisition, thereby achieving the detection effect. In the circuit design, alternating current mutual inductance current is converted into direct current through four rectifier diodes, two output signals are provided, one is analog quantity, and the output signals are output by VOUT and output to an MCU; and the direct control relay is used for switching off and switching on the power supply of the motor at the high and low levels of TTL.
Description of the circuit:
vin is obtained from an output signal of the current transformer through a bridge rectifier; the comparator compares Vin with reference voltage Vref, and if Vin is greater than Vref, the comparator outputs low level to control the relay to be disconnected.
In addition, Vin enters an ADC port (namely, a port with an A/D conversion function) of the MCU after being amplified by the amplifier;
because the signal is weak, an amplifier with adjustable amplification factor is designed; the specific circuit connection and working principle are as follows:
the output end Vin of the bridge rectifier is a signal end, the signal end is connected with the inverting input end of the operational amplifier LM393 through a resistor R0, the homodromous input end of the operational amplifier LM393 is grounded through a resistor R0, the homodromous input end of the operational amplifier LM393 is also connected with 4 input channels of the 4-out-of-one selector through 4 resistors R01-R04 respectively, the output channel of the 4-out-of-one selector is connected with the output end Vout of the operational amplifier LM393, and the Vout is connected with the ADC end of the MCU;
in addition, 2 output ports of the MCU are respectively connected with a channel selection end A and a channel selection end B of a 4-selection selector;
calculation formula of Vout and Vin:
vout ═ Vin, (Rx + R0)/R0; wherein Rx ═ R01, R02, R03, or R04; determining which resistance to select based on the gate terminal AB; and R01, R02, R03 and R04 are each different; preferred R04-5-R03-25-R02-100-R01; r01-5 × R0. can conveniently achieve span and precision switching.
The detection device is an optical detection device, and specifically comprises the steps of pushing the reaction tube into a darkroom of the detection device, detecting the color and the like of the reaction tube through illumination, or taking a picture for analysis and processing to obtain a final detection result, specifically the prior art.
Claims (1)
1. A medical intelligent biochemical detection system is characterized by comprising a base (1), a turntable (6), a liquid injection device, a cleaning device (7), a detection device (5) and a manipulator (9);
the turntable, the liquid injection device, the cleaning device, the detection device and the manipulator are all arranged on the base;
the liquid injection device, the cleaning device and the detection device are arranged around the turntable;
the turntable is provided with a plurality of reaction tube accommodating holes (4); the reaction tube accommodating holes are uniformly distributed along the circumferential direction of the turntable;
the manipulator is used for moving the reaction tube into the reaction tube accommodating hole and moving the reaction tube in the reaction tube accommodating hole out of the turntable;
the liquid injection device is used for injecting a reagent into the reaction tube positioned in the reaction tube accommodating hole;
the cleaning device is used for cleaning the reaction tube in the reaction tube accommodating hole;
the detection device is used for detecting the liquid in the reaction tube after the reagent is added, and the sample liquid is arranged in the reaction tube before the reagent is added;
a reaction tube placing position array (10) consisting of a plurality of reaction tube containing holes is arranged on the base;
the liquid injection device comprises a first liquid injection device (2) and a second liquid injection device (3);
6 reaction tube accommodating holes are arranged on the turntable; be equipped with 6 stations around the carousel, be respectively in proper order: a starting position (12), a first liquid injection level, a second liquid injection level, a detection position, a cleaning position and a reaction tube removing position (8);
the 6 stations are circumferentially and uniformly arranged;
the starting position is used for placing the reaction tube containing the sample liquid into the reaction tube containing hole on the turntable by the manipulator;
the first liquid injection level and the second liquid injection level are respectively provided with a first liquid injection device and a second liquid injection device which are respectively used for injecting a first reagent and a second reagent into the reaction tube;
a detection device is arranged at the detection position;
the reaction tube removing position is used for the manipulator to remove the reaction tube from the turntable;
the manipulator is an XYZ three-axis manipulator;
the reaction tube is provided with a label, and the detection device is internally provided with a scanning device for scanning the label;
the detection device is provided with a communication module for transmitting detection data and label data;
the medical intelligent biochemical detection system is also connected with a reaction tube label printing, transmitting and pasting system;
the reaction tube label printing, conveying and pasting system comprises a label belt conveying device, a label printing device and a label pasting device;
the label belt conveying device comprises a label belt disc, a first conveying roller, a first flattening roller, a second conveying roller and a recovery roll;
a label tape is arranged on the label tape reel; a plurality of label paper is stuck on the label belt at equal intervals;
the label tape is led out from the label tape disc and then sequentially passes through the first transmission roller, the first flattening roller, the second flattening roller and the second transmission roller to reach a rewinding roller;
the first conducting roller and the second conducting roller are used for changing the conducting direction of the label tape;
the first flattening roller and the second flattening roller are used for flattening the label tape to be horizontal, so that the label printing device can print on the label paper conveniently; the first flattening roll and the second flattening roll are both double rolls;
the label printing device is arranged between the first flattening roller and the second flattening roller and comprises a printing head and a printing support platform; the printing head is positioned above the label tape, and the printing support platform is positioned below the printing head and the label tape;
the label pasting device is used for pasting the printed label paper on the outer wall of the reaction tube;
the label pasting device comprises a label paper conveying device and a leather rolling device;
the label paper conveying device comprises a first suction cup, a rotating mechanism 36 for driving the first suction cup to rotate, a sliding rail 42 and a second suction cup capable of translating along the sliding rail; the first sucker is positioned above the second transfer roller, can suck the label paper on the label belt, sucks the side without glue, and enables the label paper to rotate 180 degrees in a vertical plane under the action of the rotating mechanism; the sucker rotates from the downward direction to the upward direction;
the second sucker can suck the label paper from the first sucker and move to the leather rolling device along the slide rail; the side with the glue is sucked, the side with the glue is only provided with the glue at two ends, and the glue is not arranged in the middle, so that the label paper cannot be stuck to the second sucking disc when the second sucking disc is loosened;
the leather rolling device comprises a pneumatic finger and 2 leather rolling rollers;
the pneumatic fingers are provided with pneumatic chucks for clamping the reaction tubes;
the 2 leather rolling rollers are all horizontally arranged, and the 2 leather rolling rollers are positioned below the pneumatic finger; the 2 leather rolling rollers are used for supporting the label paper and the reaction tube when the label paper is pasted, and are also used for driving the label paper roll to be pasted on the reaction tube through rotation; when the 2 leather rolling rollers rotate, the rotating directions of the 2 leather rolling rollers are the same;
the label paper conveying device is positioned between the pneumatic fingers and the 2 leather rolling rollers, and the label paper conveying module is used for moving the label paper to the 2 leather rolling rollers;
the bottom of the pneumatic finger is provided with at least 1 roller;
two sides of the bottom of the pneumatic finger are respectively provided with 1 group of idler wheels, and each group of idler wheels comprises 1 or 2 idler wheels;
one of the 2 peeling rollers can move transversely relative to the other roller;
the reaction tube label printing, transmitting and pasting system can be butted with the medical intelligent biochemical detection system, and provides the reaction tube pasted with label paper for the medical intelligent biochemical detection system;
the medical intelligent biochemical detection system is arranged on a vehicle driven by a battery, and a wireless charging circuit for charging the battery is arranged on the vehicle;
the intelligent automatic biochemical detection method adopted by the medical intelligent biochemical detection system comprises the following steps:
step 1: loading a reaction tube on a turntable;
placing the reaction tube containing the sample into the reaction tube containing hole on the turntable by using a manipulator;
step 2: injecting a first reagent into the reaction tube and stirring;
step 3; injecting a second reagent into the reaction tube and stirring;
and 4, step 4: a detection step;
performing photoelectric detection on the liquid in the reaction tube added with the first reagent and the second reagent by using a detection device;
and 5: cleaning;
extracting liquid from the detected reaction tube, injecting cleaning liquid, stirring, and extracting the liquid after stirring; the injection of the cleaning liquid and the liquid extraction can be repeated for a plurality of times;
step 6: removing the reaction tube;
moving the cleaned reaction tube out of the turntable by a manipulator;
the steps 1-6 are assembly line type parallel steps; steps 1-6 are carried out at the following 6 stations, respectively: the device comprises a starting position, a first liquid injection level, a second liquid injection level, a detection position, a cleaning position and a reaction tube removing position.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810021069.0A CN108303556B (en) | 2018-01-10 | 2018-01-10 | Medical intelligent biochemical detection system |
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| CN201810021069.0A CN108303556B (en) | 2018-01-10 | 2018-01-10 | Medical intelligent biochemical detection system |
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