CN108295167A - It is a kind of to treat children's rhinitis, the Chinese medicine composition of nasosinusitis and preparation and application - Google Patents
It is a kind of to treat children's rhinitis, the Chinese medicine composition of nasosinusitis and preparation and application Download PDFInfo
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- CN108295167A CN108295167A CN201810270184.1A CN201810270184A CN108295167A CN 108295167 A CN108295167 A CN 108295167A CN 201810270184 A CN201810270184 A CN 201810270184A CN 108295167 A CN108295167 A CN 108295167A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
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Abstract
Children's rhinitis, the Chinese medicine composition of nasosinusitis and preparation and application are treated the invention discloses a kind of, the Chinese medicine composition includes 5~15 parts of chrysanthemum by weight, 3~15 parts of radix scutellariae, 1~10 part of radix bupleuri, 1~10 part of raw Radix Paeoniae Alba, 3~15 parts of pinellia, 1~10 part of cassia twig, 3~15 parts of Flos Magnoliae Liliflorae.The Chinese medicine composition integrates clinical treatment experience for many years, is monarch with chrysanthemum, it is intended that liver and gall drop clearly in heat evil in inducing diaphoresis;Radix scutellariae is minister, it is intended that clearing heat and detoxicating, eliminating dampness purging intense heat;Radix bupleuri, Radix Paeoniae Alba, the tuber of pinellia, cassia twig are assistant;Flos Magnoliae Liliflorae is to make, and energy priming such as lung, stomach, the sensible inducing diaphoresis of facilitaing lung promoting the circulation of qi, all medicines share can be clearing heat and detoxicating, soothing the liver facilitaing lung, clear to drop convulsive seizure due to phlegm-fire stomach energy, can effectively treat rhinitis, nasosinusitis.Medicinal material used is gentle, does not hinder healthy tendency, does not damage tender dirty, and ingredient is simple, safe and effective and uneasy to recur, is particularly suitable for treating infant's rhinitis, nasosinusitis, has important clinical meaning and good application prospect.
Description
Technical field
The invention belongs to traditional Chinese medicine field, more particularly to a kind of Chinese prescriptions for treating children's rhinitis, nasosinusitis
And preparation and application.
Background technology
Children's rhinitis, nasosinusitis are common clinicals, and conservative treatment is generally used in treatment.It is single because of pathogenic factor complexity
Pure western medical treatment has been unable to meet clinical needs.
Clinical symptoms are different when children's rhinitis is broken out, and very big harm can be brought to child.In in daily learning life, one
A little patients can cause learning efficiency low because rhinitis causes headache, insobriety.When rhinitis influences the physiology work(of nasal cavity
When energy, patient will appear respiratory disorder, and causing blood oxygen concentration reduces, and influences the function and metabolism of its hetero-organization and organ;When
When the severe complications such as concurrent pulmonary emphysema, pulmonary heart disease, asthma, it may appear that headache, dizziness, decrease of memory, pectoralgia, uncomfortable in chest, smart
God's symptoms such as dispirited;When rhinitis influences smell mucous membrane, just will appear dysosmia, hear not the smells such as fragrant, smelly, and about
Ninety percent nasopharyngeal carcinoma is caused by rhinitis obstinate deteriorates.Therefore it can not adopt a casual attitude, treated in time to rhinitis, to avoid
Cause severe complication.
The generation of sinusitis in children and children's nasal cavity structure exception, respiratory mucosa fragility, respiratory tract infection and metamorphosis are anti-
Answer closely related, onset symptoms mostly nasal obstruction, runny nose, headache and hyposphresia, to be become apparent from morning.Early stage mostly uses
Drug therapy, but such patient anatomy and adult are not exactly the same, it in early days can be in certain journey using effective drug therapy
The influence to developing in the future is reduced on degree.But the classes drug such as conventionally employed antibiotic and hormone generally requires prolonged application, and
Reusability can increase whole body or local adverse reaction odds.In addition, clinically basic without for this group of children
The preferable rhinitis of effect that body uses, nasosinusitis drug, majority is to be reduced adult medication, there is certain unknown adverse reaction.
Invention content
The primary purpose of the present invention is that the shortcomings that overcoming the prior art and deficiency, provide a kind of for treating children's nose
Scorching, nasosinusitis Chinese medicine composition.
Another object of the present invention is to provide the Chinese medicine preparations of the Chinese medicine composition.
It is still another object of the present invention to provide the applications of the Chinese medicine composition.
The purpose of the invention is achieved by the following technical solution:
A kind of Chinese medicine composition for treating children's rhinitis, nasosinusitis, including following components by weight:
The Chinese medicine composition preferably comprises following components by weight:
Further preferably 15 parts of chrysanthemum, 10 parts of radix scutellariae, 10 parts of radix bupleuri, 8 parts of raw Radix Paeoniae Alba, 10 parts of pinellia, 10 parts of cassia twig,
12 parts of Flos Magnoliae Liliflorae;Or 5 parts of chrysanthemum, 15 parts of radix scutellariae, 10 parts of radix bupleuri, 10 parts of raw Radix Paeoniae Alba, 15 parts of pinellia, 10 parts of cassia twig, Flos Magnoliae Liliflorae
15 parts.
Various dosage forms, including decoction, tablet, capsule is made in the conventional method that this field can be used in the Chinese medicine composition
Agent, injection, powder-injection, granule, electuary, oral solution and syrup, or using tablet, capsule made of nanometer technique
Agent, injection, powder-injection or granule.
The decoction is preferably prepared via a method which to obtain:
After the Chinese medicine composition is impregnated, add water to cook to obtain.
The immersion preferably uses cold water to impregnate.
The time of the immersion is preferably 1~3 hour.
The decoction is cooked by slow fire after preferably boiling with strong fire.
The time of decoction is preferably at least 20 minutes.
A kind of Chinese medicine preparation is prepared by the Chinese medicine composition and pharmaceutically acceptable carrier.
The administering mode of the Chinese medicine preparation includes oral, injection, spraying, sucking or combinations thereof.
Application of the Chinese medicine composition or Chinese medicine preparation in preparing rhinitis, nasosinusitis drug pediatric medicament.
Children's rhinopathy is mostly that liver lung discord causes impairment of dispersing and descending function of the lung;The bright circulation of vital energy in the wrong direction of sun is not born heat, and nose key is above disturbed;Phlegm wet heat blocks
Lung key causes.So children's rhinopathy, mostly based on heat symptom-complex, especially phlegm wet heat is even more the root of children's rhinopathy.Diseases caused by external factors can also draw
Since childhood rhinopathy, but mostly inducement are not root places.Children are in growth phase, such as the nascent sun, yang-energy mistake
It contains, and because the rotten breast delicious food of often feeding grows greasy product, or hungry immoderate impairing the spleen and stomach of satisfying, causes the stagnant heat of taste.The stagnant gas of taste is not transported
Change and confine edema with the liver involved, irritability does not dredge courage mistake catharsis and life is damp and hot, above disturbs lung gold and causes impairment of dispersing and descending function of the lung, obstructed turbid nasal discharge head of having a stuffy nose occurs
Ache the diseases such as dizziness.Therefore, Chinese medicine composition of the invention integrates clinical treatment experience for many years, to treat the chrysanthemum of heat symptom-complex as monarch
Medicine, diaphoretic medicine, which is assistant, to be made.
Chrysanthemum is monarch in side, it is intended that liver and gall drop clearly in heat evil in inducing diaphoresis, while nourishing liver the moon will not the deficiency of the liver-yin and life is scorching.
Radix scutellariae is minister, it is intended that clearing heat and detoxicating, eliminating dampness purging intense heat solves cardiopulmonary liver and gall heat evil, rushes down positive open fire heat clearly.
Radix bupleuri, Radix Paeoniae Alba, the tuber of pinellia, cassia twig are assistant, and wherein the purpose of radix bupleuri, Radix Paeoniae Alba is the strongly fragrant of soothing the liver courage, makes the gas hair tonic of liver and gall
Catharsis is not trapped in soil, while energy promoting the circulation of qi helps lung qi a surname's hair.The bright stomach Qi of tuber of pinellia drop sun, stomach Qi must drop, not on disturb in lung, lung
Respectful drop is under.The logical battalion Wei Biaoli of cassia twig a surname, and energy middle benefit gas promoting the circulation of qi, not only contribute to dispersing and lowering lung-QI, but also the cold and cool medicine damage spleen of the system of capable of helping
Stomach.
Flos Magnoliae Liliflorae is to make, can priming such as lung, stomach, the sensible inducing diaphoresis of facilitaing lung promoting the circulation of qi makes to solve heresy of table is rapid, in table together
It controls.
Medicine-feeding shares can be clearing heat and detoxicating, soothing the liver facilitaing lung, clear drop convulsive seizure due to phlegm-fire stomach energy, indispensable, and it is ill can to solve nose key.
Since formula herbs are gentle, do not hinder healthy tendency, do not damage it is tender dirty, so being particularly suitable for children rhinopathy.
The present invention has the following advantages and effects with respect to the prior art:
(1) Chinese medicine composition of the invention synthesis clinical treatment experience for many years, to treat the chrysanthemum of heat symptom-complex as monarch drug in a prescription, inducing diaphoresis
Medicine, which is assistant, to be made, and indispensable, all medicines share can be clearing heat and detoxicating, soothing the liver facilitaing lung, clear to drop convulsive seizure due to phlegm-fire stomach energy, and it is ill can to solve nose key;Therefrom
The position for the monarch that dialectical angle illustrates between each component is cured, it is abundant to improve Chinese medicine theory system.
(2) since formula herbs are gentle, do not hinder healthy tendency, do not damage it is tender dirty, so being particularly suitable for treating infant's rhinitis, nasosinusitis is controlled
It treats;Ingredient is simple, but safely, effectively and uneasy to recur, mainly for this specific group of children, has important clinical meaning
Justice.
(3) Chinese medicine composition energy rapid recovery rhinopathy symptom of the invention, can take effect, can effectively treat for general one week
Virgin rhinitis, nasosinusitis, total effective rate are up to 97.1%, obvious adverse reaction are had no during medication.
Specific implementation mode
With reference to embodiment, the present invention is described in further detail, and embodiments of the present invention are not limited thereto.
Embodiment 1
Record is come infant 93 of going to a doctor, wherein man 60, female 33 is 3~14 years old age, 8 years old average.The course of disease 1~10 year,
It is 3 years average.
Take Chinese medicine composition of the present invention " 15 grams of chrysanthemum, 10 grams of radix scutellariae, 10 grams of radix bupleuri, 8 grams of raw Radix Paeoniae Alba, 10 grams of pinellia,
10 grams of cassia twig, 12 grams of Flos Magnoliae Liliflorae ", which adds, to be decocted in water for oral dose.After drug is impregnated 2 hours with cold water, 20 points are cooked by slow fire after boiling with strong fire
Clock obtains decoction.One dose per day (is taken) in three times, seven days as a treatment course.Curative effect is recorded after one course for the treatment of.
Observation index:The remissions situations such as nasal obstruction, runny nose, headache dysosmia, concha swelling recovery, nasal cavity cleaning feelings
Condition, nasal sinus area tenderness alleviate situation.
Efficacy assessment standard:
(1) effective:Nasal obstruction, runny nose, headache syndromes disappear, and smell restores, and concha swelling subsides, nasal cavity cleaning, nasal sinus area
Tenderness disappears;
(2) effectively:Nasal obstruction, runny nose, headache syndromes are alleviated, and concha swelling mitigates, and nasal secretion is reduced to effectively;
(3) invalid:Symptom and sign is without change after medication.
The results are shown in Table 1, it is seen that Chinese medicine composition energy rapid recovery rhinopathy symptom of the invention can effectively treat children
Rhinitis, nasosinusitis, total effective rate are up to 97.1%, obvious adverse reaction are had no during medication.
Table 1
It is effective | Effectively | In vain | |
Number of cases | 57 | 34 | 2 |
Percentage | 61.3% | 36.6% | 2.1% |
Model case
Mr. Wang, male, people from Hebei province, 8 years old, student.The yellow nasal mucus of patient's nasal obstruction, stream has a headache, spits yellow phlegm, generates heat.It is anti-over 1 year
Again because flu, fatigue and emotional factors etc. induce nasion portion pain, companion has a sleepless night, is forgetful, irritated.Once gone to a doctor repeatedly in nerve
Section, the inspection such as row electroencephalogram, rheoencephalogram is no abnormal, takes a variety of Chinese and western drugs, including antibiotic, vasodilator etc.
Without positive effect, studying and living is seriously affected.It is diagnosed as chronic nasosinusitis.
Take prescription of the present invention " 5 grams of chrysanthemum, 15 grams of radix scutellariae, 10 grams of radix bupleuri, 10 grams of raw Radix Paeoniae Alba, 15 grams of pinellia, cassia twig 10
Gram, 15 grams of Flos Magnoliae Liliflorae " decoction, after drug is impregnated 2 hours with cold water, decoction is cooked by slow fire 20 minutes to obtain after boiling with strong fire.
One dose per day (is taken) in three times, seven days as a treatment course.Do not generate heat after 3 doses, have a headache, the symptoms such as irritated, thirsty of having a stuffy nose it is bright
Aobvious to mitigate, phlegm is yellowish, and stool is normal.It is recommended that taking two courses for the treatment of, preventing cold is paid attention to.3 years no relapse of follow-up.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, it is other it is any without departing from the spirit and principles of the present invention made by changes, modifications, substitutions, combinations, simplifications,
Equivalent substitute mode is should be, is included within the scope of the present invention.
Claims (10)
1. a kind of for treating the Chinese medicine composition of children's rhinitis, nasosinusitis, which is characterized in that comprising it is following by weight
Component:
2. the Chinese medicine composition according to claim 1 for treating children's rhinitis, nasosinusitis, which is characterized in that include
Following components by weight:
3. the Chinese medicine composition according to claim 1 for treating children's rhinitis, nasosinusitis, which is characterized in that include
Following components by weight:
15 parts of chrysanthemum, 10 parts of radix scutellariae, 10 parts of radix bupleuri, 8 parts of raw Radix Paeoniae Alba, 10 parts of pinellia, 10 parts of cassia twig, 12 parts of Flos Magnoliae Liliflorae.
Or 5 parts of chrysanthemum, 15 parts of radix scutellariae, 10 parts of radix bupleuri, 10 parts of raw Radix Paeoniae Alba, 15 parts of pinellia, 10 parts of cassia twig, 15 parts of Flos Magnoliae Liliflorae.
4. being used to treat the Chinese medicine composition of children's rhinitis, nasosinusitis, feature according to claims 1 to 3 any one of them
It is:
The conventional method that this field can be used in the Chinese medicine composition is made various dosage forms, including decoction, tablet, capsule,
Injection, powder-injection, granule, electuary, oral solution and syrup, or using tablet, capsule, needle made of nanometer technique
Agent, powder-injection or granule.
5. the Chinese medicine composition according to claim 4 for treating children's rhinitis, nasosinusitis, which is characterized in that described
Decoction be prepared via a method which to obtain:
After the Chinese medicine composition is impregnated, add water to cook to obtain.
6. the Chinese medicine composition according to claim 5 for treating children's rhinitis, nasosinusitis, it is characterised in that:
The immersion is impregnated using cold water;
The time of the immersion is 1~3 hour.
7. the Chinese medicine composition according to claim 5 for treating children's rhinitis, nasosinusitis, it is characterised in that:
The decoction is to be cooked by slow fire after boiling with strong fire.
The time of decoction is at least 20 minutes.
8. a kind of Chinese medicine preparation, it is characterised in that:
By according to claim 1~7 any one of them for treating children's rhinitis, the Chinese medicine composition of nasosinusitis and pharmaceutically
Acceptable carrier is prepared.
9. Chinese medicine preparation according to claim 8, it is characterised in that:
The administering mode of the Chinese medicine preparation includes oral, injection, spraying, sucking or combinations thereof.
10. claim 1~7 any one of them is for treating children's rhinitis, the Chinese medicine composition of nasosinusitis or claim 8
Application of~9 any one of them Chinese medicine preparations in preparing rhinitis, nasosinusitis drug pediatric medicament.
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Cited By (1)
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CN112891507A (en) * | 2021-04-27 | 2021-06-04 | 海南海府科技有限公司 | A Chinese medicinal composition for treating rhinitis, and its preparation method |
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KR20010067653A (en) * | 2001-03-02 | 2001-07-13 | 김찬호 | Curing agent for allergic rhinitis and asthma, and the manufacturing method thereof |
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CN112891507A (en) * | 2021-04-27 | 2021-06-04 | 海南海府科技有限公司 | A Chinese medicinal composition for treating rhinitis, and its preparation method |
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