CN108289367A - A kind of medical proton-synchrotron - Google Patents
A kind of medical proton-synchrotron Download PDFInfo
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- CN108289367A CN108289367A CN201810071323.8A CN201810071323A CN108289367A CN 108289367 A CN108289367 A CN 108289367A CN 201810071323 A CN201810071323 A CN 201810071323A CN 108289367 A CN108289367 A CN 108289367A
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- magnet
- sextupole
- quadrupole
- combined
- deflection
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- 238000002347 injection Methods 0.000 claims description 16
- 239000007924 injection Substances 0.000 claims description 16
- 230000001133 acceleration Effects 0.000 claims description 4
- 230000005284 excitation Effects 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 8
- 229910052742 iron Inorganic materials 0.000 description 4
- 238000010276 construction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005086 pumping Methods 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 241000209094 Oryza Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005265 energy consumption Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 238000005452 bending Methods 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000001064 degrader Substances 0.000 description 1
- 238000004146 energy storage Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000002463 transducing effect Effects 0.000 description 1
Classifications
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H13/00—Magnetic resonance accelerators; Cyclotrons
- H05H13/04—Synchrotrons
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H2277/00—Applications of particle accelerators
- H05H2277/10—Medical devices
- H05H2277/11—Radiotherapy
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- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Particle Accelerators (AREA)
Abstract
Include by three straight sections connections to form three deflection dipolar magnets of loop configuration, the straight sections include horizontal focusing and horizontal defocus quadrupole and sextupole combined magnet the present invention relates to a kind of medical proton-synchrotron.The present invention combines the horizontal focusing of control operating point by using small number of deflection dipolar magnet or defocuses quadrupole electromagnet, loopful envelope function is controlled in smaller level, effectively increase the acceptance and proton storage number of synchrotron, proton utilization rate and duty ratio are improved, treatment time is shortened；In addition, the structure of the present invention is closely, reduce unnecessary gap and magnet device, to realize the function of medical accelerator using component number as few as possible, reduces synchrotron the space occupied, thereby reduce building cost and treatment cost.
Description
Technical field
The present invention relates to for oncotherapy synchrotron field more particularly to a kind of medical proton synchrotron accelerate
Device.
Background technology
Excellent Bragg peak character makes it become means the most advanced in oncotherapy to proton in the depth direction
One of, the construction of proton therapeutic appts and therapeutic community is more and more in the world at present.Proton in operation at present and construction is controlled
Cancer accelerator is mainly cyclotron and synchrotron.
Cyclotron can provide stable continuous beam, and line cut-out and opening speed quickly, can meet breathing
The requirement of gate.But cyclotron change energy dependence is the mechanical device being placed on high energy line --- degrader,
Beam energy is reduced using scattering；Its advantage is that energy adjustment is rapid, 50 milliseconds one grade of change energy velocity may be implemented,
Quick multiple scanning pattern can be supported to treat mobile tumour；But the disadvantage is that scattering causes line utilization rate very low, when treatment
When minimum energy 70MeV by efficiency less than 1%, a large amount of lines damages caused by scattering caused by dropping energy and energy selection later
Mistake can cause greatly to radiate, and prodigious pressure is caused to radiation protection and equipment safety.
Compared with cyclotron, the obvious advantage of synchrotron is that it can easily carry out the energy of line
It adjusts, to adapt to the needs that radiotherapy accurately changes ion energy, does not need additional energy drop energy piece, it can be ensured that phase
To the environment of clean (radiation is small).After using new multipotency amount lead-out mode, the intrinsic transducing time is slow, causes nothing
The shortcomings that imitating treatment time length and can not adapting to quick multiple scanning is substantially not present.
Have patent document CN105392270A in designs such as specific magnet, power supplys, it is contemplated that this new technology, from
And greatly reduce treatment time.But the design of this accelerator have the disadvantages that for：When it is complex, use 8
Block deflects dipolar magnet and 12 pieces focus and defocus quadrupole electromagnet, and the increase of element means the decline of reliability；Second is that structure
Not compact enough, the gap between element and element is at waste；Third, energy consumption is higher, magnet is powerful device, the liter of cycle
Energy process can be dropped and waste big energy；Fourth, envelope function is still larger, thus space charge effect is larger, and particle is caused to be deposited
It stores up less.
Invention content
In order to solve the problems, such as above-mentioned existing synchrotron, the present invention is intended to provide a kind of medical proton synchrotron
Accelerator.
Medical proton-synchrotron of the present invention includes by three straight sections connections to form loop configuration
Three deflection dipolar magnets, the straight sections include horizontal focusing and horizontal defocus quadrupole and sextupole combined magnet.
The deflection dipolar magnet be first, second, and third deflection dipolar magnet, wherein first deflection dipolar magnet and
Second deflection dipolar magnet is connected, and the second deflection dipolar magnet is connected with third deflection dipolar magnet, and third deflects dipolar magnet
Also it is connected to constitute a loop configuration with the first deflection dipolar magnet.
The four sextupoles combined magnet is the first, second, and third horizontal focusing quadrupole and sextupole combined magnet, Yi Ji
One, second and third horizontal defocus quadrupole and sextupole combined magnet, wherein first level focus quadrupole and sextupole combined magnet and
First level defocuses quadrupole and sextupole combined magnet is connected between the first deflection dipolar magnet and the second deflection dipolar magnet, the
Two horizontal focusing quadrupoles are connected to the second deflection two with sextupole combined magnet and the second horizontal defocus quadrupole with sextupole combined magnet
Between pole magnet and third deflection dipolar magnet, third horizontal focusing quadrupole and sextupole combined magnet and third horizontal defocus quadrupole
It is connected between third deflection dipolar magnet and the first deflection dipolar magnet with sextupole combined magnet.
Third deflects and is connected with third horizontal focusing quadrupole and six in turn between dipolar magnet and the first deflection dipolar magnet
Pole combined magnet, the first injection bump magnet, high-frequency acceleration device and third horizontal defocus quadrupole and sextupole combined magnet.
Third horizontal focusing quadrupole is connected with sextupole combined magnet and draws magnetostatic septum magnet.
It is connected with first level in turn between first deflection dipolar magnet and the second deflection dipolar magnet and focuses quadrupole and six
Pole combined magnet, lateral high frequency pumping electrode, the second injection bump magnet, injection electrostatic cutting plate and first level defocus
Quadrupole and sextupole combined magnet.
Injection electrostatic cutting plate is connected with the magnetostatic septum magnet of injection.
It is connected with the second horizontal focusing quadrupole and six in turn between second deflection dipolar magnet and third deflection dipolar magnet
Pole combined magnet, third injection bump magnet, extraction electrostatic cutting plate and the second horizontal defocus quadrupole combine magnetic with sextupole
Iron.
The deflection dipolar magnet is superconducting magnet or conventional magnet.
The present invention is by using the horizontal focusing effect and horizontal focusing quadrupole electromagnet and horizontal defocus for deflecting dipolar magnet
Magnet effect reaches double-directional focusing, can control its horizontal and vertical envelope function all in smaller level.With patent document
The technical solution of CN105392270A is compared, although the vertical envelope function of the invention bigger in horizontal defocus quadrupole electromagnet,
But the smaller in the bending iron more sensitive to envelope, the acceptance of synchrotron is effectively increased, proton storage is increased
Number improves proton utilization rate and duty ratio, shortens treatment time；And small envelope function means smaller magnet
Aperture and small magnet energy storage, also reduce energy expenditure；Less magnet quantity decreases the perimeter of entire accelerator, from
And the space of synchrotron is efficiently utilized, and then the construction cost of device and building is farthest reduced, it reduces
Treatment cost.In short, the present invention by using it is small number of deflection dipolar magnet combine control operating point horizontal focusing or
Quadrupole electromagnet is defocused, loopful envelope function is controlled in smaller level, the acceptance and proton of synchrotron are effectively increased
Number is stored, proton utilization rate and duty ratio are improved, shortens treatment time；In addition, the structure of the present invention is closely, reduce
Unnecessary gap and magnet device are reduced with being realized the function of medical accelerator using component number as few as possible
Synchrotron the space occupied, thereby reduces building cost and treatment cost.
Description of the drawings
Fig. 1 is the structural schematic diagram of medical proton-synchrotron according to a preferred embodiment of the present invention；
Fig. 2 is the schematic diagram of the envelope function of the medical proton-synchrotron in Fig. 1.
Specific implementation mode
Below in conjunction with the accompanying drawings 1~2, presently preferred embodiments of the present invention is provided, and be described in detail, makes to be better understood when
Function, the feature of the present invention.
As shown in Figure 1, medical proton-synchrotron according to the present invention includes the first, second, and third two pole magnetic of deflection
Iron 1,2,3, wherein the first deflection dipolar magnet 1 is connected with the second deflection dipolar magnet 2, the second deflection dipolar magnet 2 and third
It deflects dipolar magnet 3 to be connected, third deflection dipolar magnet 3 is also connected with the first deflection dipolar magnet 1 to constitute a loop configuration
With deflected beam (beam direction is the clockwise direction of loop configuration in Fig. 1).
Medical proton-synchrotron further includes the first, second, and third straight sections, wherein first straight line section is connected to
Between one deflection dipolar magnet 1 and second deflects dipolar magnet 2, second straight line section is connected to the second deflection dipolar magnet 2 and the
Between three deflection dipolar magnets 3, third straight sections are connected between the third deflection deflection dipolar magnet 1 of dipolar magnet 3 and first.
First straight line section includes the be connected in turn between the first deflection dipolar magnet 1 and second deflection dipolar magnet 2
One horizontal focusing quadrupole is injected with the lateral high frequency pumping electrode 31 of sextupole combined magnet 21, one, the second injection bump magnet 14, one
Electrostatic cutting plate 12 and first level defocus quadrupole and sextupole combined magnet 41.Wherein, first straight line section further includes and injects
The one of the connection of electrostatic cutting plate 12 injects magnetostatic septum magnet 11.
Second straight line section includes the be connected in turn between the second deflection dipolar magnet 2 and third deflection dipolar magnet 3
Two horizontal focusing quadrupoles draw electrostatic cutting plate 32 and second with sextupole combined magnet 22, third injection bump magnet 15, one
Horizontal defocus quadrupole and sextupole combined magnet 42.
Third straight sections include be connected in turn third deflection dipolar magnet 3 and first deflect between dipolar magnet 1 the
Three horizontal focusing quadrupoles and sextupole combined magnet 23, the first injection bump magnet 13, a high-frequency acceleration device 51 and third water
It is flat to defocus quadrupole and sextupole combined magnet 43.Wherein, third straight sections further include being combined with third horizontal focusing quadrupole with sextupole
The one of the connection of magnet 23 draws magnetostatic septum magnet 33.
It is connected by vacuum tube (not shown) between above-mentioned each component.
In actual use, low energy proton beam is provided by injecting magnetostatic septum magnet by injector in a treatment cycle
11, injection electrostatic cutting plate 12, the first, second, and third injection bump magnet 13,14,15, first, second, and third deflection two
Pole magnet 1,2,3 is injected into the medical proton-synchrotron of the present invention and stores；Then, it is required according to treatment, passes through synchronization
Rise the field strength of the first, second, and third deflection dipolar magnet 1,2,3, proton can measure under the action of high-frequency acceleration device 51
To promotion.Under corresponding treatment energy, excitation the first, second, and third horizontal defocus quadrupole and sextupole combined magnet 41,42,
43 6 pole component makes operating point be moved adjacent to third order resonance line, and proton is in lateral high frequency pumping electrode 31, first, second
It is diffused into extraction channel under the action of third horizontal focusing quadrupole and sextupole combined magnet 21,22,23, is cut by drawing electrostatic
It cuts plate 32 and draws magnetostatic septum magnet 33 and be drawn out to outside proton-synchrotron until patient.When needed, it can treat
Stop drawing in period, and switches energy and implement to draw.
Fig. 2 is the corresponding horizontal and vertical line envelope function of the present embodiment, wherein the size of ordinate representative function,
Unit is rice (m), and abscissa indicates that the lengthwise position in synchrotron, unit are rice (m).As it can be seen that the present invention has packet
Network function is small, the big feature of effective acceptance, simulates calculation shows that more protons can be stored.
In conclusion the present embodiment use 3 pieces deflection dipolar magnet combination quadrupole iron focusing reduce envelope function with
Shorten perimeter, resonance six pole magnet combination greatly simplifies number of elements on quadrupole electromagnet, reduces energy consumption.
In addition to previous examples, the present invention can also have other variations, i.e., every claims applied according to the present invention
And simple, equivalent changes and modifications made by description, fall within the claims of patent of the present invention.This hair
Bright not detailed description is routine techniques content.
Claims (9)
1. a kind of medical proton-synchrotron, which is characterized in that medical proton-synchrotron includes passing through three straight sections
Connection to form three of loop configuration deflection dipolar magnets, the straight sections include horizontal focusing and horizontal defocus quadrupole and
Sextupole combined magnet.
2. medical proton-synchrotron according to claim 1, which is characterized in that the deflection dipolar magnet is the
One, second and third deflection dipolar magnet (1,2,3), wherein first deflection dipolar magnet (1) and second deflects dipolar magnet
(2) be connected, second deflection dipolar magnet (2) and third deflection dipolar magnet (3) is connected, third deflection dipolar magnet (3) also with
First deflection dipolar magnet (1) is connected to constitute a loop configuration.
3. medical proton-synchrotron according to claim 2, which is characterized in that the four sextupoles combined magnet is the
One, second and third horizontal focusing quadrupole and sextupole combined magnet (21,22,23) and the first, second, and third horizontal defocus
Quadrupole and sextupole combined magnet (41,42,43), wherein first level focuses quadrupole and sextupole combined magnet (21) and the first water
It is flat defocus quadrupole and sextupole combined magnet (41) be connected to the first deflection dipolar magnet (1) and second deflect dipolar magnet (2) it
Between, the second horizontal focusing quadrupole is connect with sextupole combined magnet (22) and the second horizontal defocus quadrupole with sextupole combined magnet (42)
Between the second deflection dipolar magnet (2) and third deflection dipolar magnet (3), third horizontal focusing quadrupole and sextupole combined magnet
(23) and third horizontal defocus quadrupole is connected to third deflection dipolar magnet (3) and the first deflection two with sextupole combined magnet (43)
Between pole magnet (1).
4. medical proton-synchrotron according to claim 3, which is characterized in that third deflect dipolar magnet (3) and
It is connected with third horizontal focusing quadrupole and sextupole combined magnet (23), the first injection between first deflection dipolar magnet (1) in turn
Bumper magnet (13), high-frequency acceleration device (51) and third horizontal defocus quadrupole and sextupole combined magnet (43).
5. medical proton-synchrotron according to claim 4, which is characterized in that third horizontal focusing quadrupole and sextupole
Combined magnet (23), which is connected with, draws magnetostatic septum magnet (33).
6. medical proton-synchrotron according to claim 3, which is characterized in that first deflection dipolar magnet (1) and
It is connected with first level between second deflection dipolar magnet (2) in turn and focuses quadrupole and sextupole combined magnet (21), lateral high frequency
Excitation electrode (31), the second injection bump magnet (14), injection electrostatic cutting plate (12) and first level defocus quadrupole and six
Pole combined magnet (41).
7. medical proton-synchrotron according to claim 6, which is characterized in that injection electrostatic cutting plate (12) connects
There is the magnetostatic septum magnet (11) of injection.
8. medical proton-synchrotron according to claim 3, which is characterized in that second deflection dipolar magnet (2) and
The second horizontal focusing quadrupole is connected between third deflection dipolar magnet (3) in turn to inject with sextupole combined magnet (22), third
Bumper magnet (15) draws electrostatic cutting plate (32) and the second horizontal defocus quadrupole and sextupole combined magnet (42).
9. medical proton-synchrotron according to claim 1, which is characterized in that the deflection dipolar magnet is superconduction
Magnet or conventional magnet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810071323.8A CN108289367A (en) | 2018-01-25 | 2018-01-25 | A kind of medical proton-synchrotron |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810071323.8A CN108289367A (en) | 2018-01-25 | 2018-01-25 | A kind of medical proton-synchrotron |
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| Publication Number | Publication Date |
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| CN108289367A true CN108289367A (en) | 2018-07-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201810071323.8A Pending CN108289367A (en) | 2018-01-25 | 2018-01-25 | A kind of medical proton-synchrotron |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113382530A (en) * | 2021-07-22 | 2021-09-10 | 中国科学院上海高等研究院 | Medical proton synchrotron of super high dose rate |
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|---|---|---|---|---|
| JPH056800U (en) * | 1991-07-04 | 1993-01-29 | 石川島播磨重工業株式会社 | Ring type particle accelerator |
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2018
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113382530A (en) * | 2021-07-22 | 2021-09-10 | 中国科学院上海高等研究院 | Medical proton synchrotron of super high dose rate |
| CN113382530B (en) * | 2021-07-22 | 2023-11-10 | 中国科学院上海高等研究院 | Medical proton synchrotron with ultra-high dosage rate |
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Effective date of registration: 20221215 Address after: 201800 Shanghai city Jiading District Road No. 2019 Applicant after: SHANGHAI INSTITUTE OF APPLIED PHYSICS, CHINESE ACADEMY OF SCIENCES Applicant after: Shanghai Alliance Investment Ltd. Address before: 201800 Shanghai city Jiading District Road No. 2019 Applicant before: SHANGHAI INSTITUTE OF APPLIED PHYSICS, CHINESE ACADEMY OF SCIENCES |
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Application publication date: 20180717 |