CN108273009B - Traditional Chinese medicine pill for treating condyloma acuminata - Google Patents
Traditional Chinese medicine pill for treating condyloma acuminata Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine pill for treating condyloma acuminatum, belonging to the technical field of Chinese herbal medicines. Thirty-three traditional Chinese medicine raw materials such as radix bupleuri, radix curcumae, angelica sinensis, red paeony root, honeysuckle, forsythia and the like are subjected to microwave heating sterilization, crushed into fine powder by a crusher, sieved by a sieve, dried, prepared into pills with refined honey and polished to obtain the traditional Chinese medicine composition. The invention has the effects of eliminating dampness and killing insects, clearing heat and expelling toxin, reducing swelling and curing sore, soothing liver and relieving depression, cooling blood and removing blood stasis, removing putrefaction and promoting granulation and promoting aging, can effectively treat both symptoms and root causes of condyloma acuminatum patients, has high cure rate, low recurrence rate and small side effect on human bodies, has simple preparation process and convenient administration, and is particularly suitable for treating condyloma acuminatum patients.
Description
Technical Field
The invention relates to a traditional Chinese medicine pill for treating condyloma acuminatum, belonging to the technical field of Chinese herbal medicines.
Background
Condyloma acuminata is a skin disease that is caused by infection with human papilloma virus, which often occurs around the anus and genitalia. Condyloma acuminata is usually generated in the glans, coronary sulcus, prepuce frenum, urethral orifice, penis, perineum, anus, rectum, vaginal orifice, clitoris, vagina, cervix and other parts. It is usually manifested as a pale-red papule with soft texture, sharp tip and gradually increasing size, with or without a handle. Patients often have foreign body sensation, burning, itching or a feeling of sexual hindrance. The wart bodies of a few patients can grow into huge condyloma acuminatum or malignant change. The modern medicine is generally treated by western medicines such as external podophyllum emodi ester tincture, trichloroacetic acid, imiquimod cream and the like, and has side effects of certain systemic toxicity or greater irritation and the like on a human body; serious patients are usually treated by methods such as laser, freezing, electrocautery, microwave and the like, great wounds are caused to human bodies, the warts cannot be completely removed by the methods, the roots of the warts continuously grow out of the skin after the warts are atrophied and flattened by the treatment methods to form new warts, and the warts tend to grow longer and larger, have high recurrence rate and are easy to cause the immunity of the patients to be reduced.
The traditional Chinese medicine considers that the main pathogenesis of condyloma acuminatum is the verruca acuminatum caused by the fact that the sexual intercourse is unclean or dirty objects are indirectly contacted, damp-heat toxin invades vulva skin mucosa from the outside, and stagnation heat of the liver channel, disharmony of qi and blood and the combination of damp-heat toxin are caused. The damp-toxin is a yin pathogen, which is sticky in nature and difficult to remove, and tends to damage healthy qi. The condyloma acuminatum is easy to recur because of the lingering pathogen due to deficiency of the healthy qi. However, some existing oral Chinese patent medicines such as gentian liver-fire purging pills, forsythia toxin-vanquishing pills and the like belong to broad-spectrum toxin expelling medicines, are difficult to aim at the characteristics of condyloma acuminatum lesion, have long treatment course and can not achieve good curative effect particularly on some stubborn cases.
Disclosure of Invention
The invention aims to: provides a Chinese medicinal pill for treating condyloma acuminatum, which can eliminate dampness and parasites, clear heat and expel toxin, reduce swelling and cure sore, sooth liver and relieve depression, cool blood and remove blood stasis, remove slough and promote granulation, has no traumatic and side effects and can radically cure the wart with low recurrence rate and low treatment cost.
The technical scheme of the invention is as follows:
a traditional Chinese medicine pill for treating condyloma acuminatum is characterized in that: the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight (unit: g):
bupleurum root 45-55 curcuma root 75-85 angelica 95-105 red peony root 75-85
Honeysuckle flower 45-55 weeping forsythia 75-85 rhubarb 45-55 mirabilite 55-65
95-105 parts of radix sophorae flavescentis, 95-105 parts of rhizoma smilacis glabrae, 45-55 parts of golden cypress, 45-55 parts of semen plantaginis, 25-35 parts of
25-35 herba patriniae, 35-45 fructus kochiae, 35-45 fructus cnidii, 35-45 herba artemisiae scopariae
35-45 of snake slough, 35-45 of cicada slough, 45-55 of fineleaf schizonepeta herb, 35-45 of divaricate saposhnikovia root
25-35 parts of angelica dahurica, 55-65 parts of cordate houttuynia, 75-85 parts of tamarix chinensis, 45-55 parts of ephedra
45-55 cassia twig, 55-65 almond, 55-65 bulbus fritillariae cirrhosae, 55-65 thunberg fritillary bulb, 75-85
45-55 parts of rhizoma atractylodis, 55-65 parts of Chinese yam, 75-85 parts of white hyacinth bean and 45-55 parts of pepper
Raw licorice root 25-35
The traditional Chinese medicine pill for treating condyloma acuminatum is prepared from the following traditional Chinese medicine raw materials in parts by weight (unit: g):
bupleuri radix 48-52, radix Curcumae 78-82, radix Angelicae sinensis 98-102, radix Paeoniae Rubra 78-82
Honeysuckle flower 48-52 capsule of weeping forsythia 78-82 rheum officinale 48-52 mirabilite 58-62
98-102 parts of radix sophorae flavescentis, 98-102 parts of rhizoma smilacis glabrae, 48-52 parts of golden cypress, 48-52 parts of semen plantaginis, 28-32 parts of semen plantaginis
Herba Artemisiae Scopariae 28-32 herba Patriniae 38-42 Kochiae fructus 38-42 fructus Cnidii 38-42
38-42 snake slough, 38-42 cicada slough, 48-52 schizonepeta, 38-42 divaricate saposhnikovia root
Radix Angelicae Dahuricae 28-32 herba Houttuyniae 58-62 ramulus et folium Tamaricis 78-82 herba Ephedrae 48-52
Cassia twig 48-52 almond 58-62 bulbus fritillariae cirrhosae 58-62 thunberg fritillary bulb 78-82
Rhizoma atractylodis 48-52, Chinese yam 58-62, white hyacinth bean 78-82 and zanthoxylum 48-52
28-32 of raw licorice
The traditional Chinese medicine pill for treating condyloma acuminatum is prepared from the following traditional Chinese medicine raw materials in parts by weight (unit: g):
bupleuri radix 50, Curcmae rhizoma 80, Angelicae Gigantis radix 100, and radix Paeoniae Rubra 80
Honeysuckle flower 50, weeping forsythia 80, rhubarb 50 and mirabilite 60
Radix Sophorae Flavescentis 100, rhizoma Smilacis Glabrae 100, cortex Phellodendri 50, semen plantaginis 30
Herba Artemisiae Scopariae 30 herba Patriniae 40 fructus Kochiae 40 fructus Cnidii 40
40 snake slough, 40 cicada slough, 40 schizonepeta, 50 divaricate saposhnikovia root and 40
Radix Angelicae Dahuricae, herba Houttuyniae, 60 ramulus et folium Tamaricis, 80 herba Ephedrae, 50
Cassia twig 50 apricot kernel 60 Sichuan fritillary bulb 60 Zhejiang fritillary bulb 80
50 rhizoma atractylodis, 60 Chinese yam, 80 white hyacinth bean and 50 zanthoxylum bungeanum
Radix Glycyrrhizae 30
The preparation method of the traditional Chinese medicine pill for treating condyloma acuminatum comprises the following steps:
weighing the raw materials of thirteen traditional Chinese medicines including radix bupleuri, radix curcumae, angelica sinensis, radix paeoniae rubra, honeysuckle, fructus forsythiae, rheum officinale, mirabilite, radix sophorae flavescentis, rhizoma smilacis glabrae, cortex phellodendri, semen plantaginis, oriental wormwood, patrinia, fructus kochiae, fructus cnidii, periostracum serpentis, periostracum cicadae, herba schizonepetae, radix sileris, radix angelicae, herba houttuyniae, tamarix chinensis, ephedra, cassia twig, almond, bulbus fritillariae cirrhosae, fritillaria thunbergii, rhizoma atractylodis, Chinese yam, white hyacinth beans, pepper and raw liquorice in parts by weight, mixing, heating and sterilizing for 4 minutes by using microwaves, crushing the raw materials of: 1, adding refined honey, and preparing into big honeyed pills, namely the finished product of the traditional Chinese medicine pills for treating condyloma acuminatum.
The specification of the invention is as follows: each pill weighs 12 g.
The application and dosage are as follows: the invention is a medicine for oral administration, which is taken with warm boiled water, 1 pill is taken 1 hour after meal in the morning, in the middle of the day and at night, and 1 month is 1 course of treatment.
The medicine property characteristics and the efficacy of each component raw material are as follows:
bupleurum root: pungent and bitter in flavor and slightly cold in nature. It enters liver, gallbladder and lung meridians. Harmonize exterior and interior, soothe liver, relieve depression, raise yang, lift sinking, allay fever and check malaria. Can be used for treating common cold, fever, alternating chills and fever, distending pain in chest and hypochondrium, menoxenia, uterine prolapse, and proctoptosis. Modern pharmacological research proves that: bupleuri radix has antibacterial, antiviral, and liver injury resisting effects.
Turmeric root-tuber: pungent, bitter and cold. It enters liver, heart and lung meridians. Move qi and remove blood stasis, clear heart fire and relieve depression, promote bile flow and cure jaundice. Can be used for treating amenorrhea, dysmenorrhea, chest and abdomen distention and pain, pricking pain, fever unconsciousness, epilepsy, jaundice, and dark urine.
Chinese angelica: sweet, pungent and warm. It enters liver, heart and spleen meridians. Tonify blood, activate blood, regulate menstruation, alleviate pain, moisten intestines to relieve constipation. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, constipation due to intestinal dryness, rheumatic arthralgia, traumatic injury, superficial infection, pyocutaneous disease.
Red peony root: bitter and slightly cold. It enters liver meridian. Clear heat and cool blood, dissipate blood stasis and alleviate pain. Can be used for treating macula due to toxic heat, hematemesis, epistaxis, conjunctival congestion, swelling and pain, liver depression, hypochondriac pain, amenorrhea, dysmenorrhea, abdominal pain, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
Honeysuckle flower: sweet and cold in nature. It enters lung and stomach meridians. Clearing away heat and toxic material, diminishing inflammation and relieving swelling. It can be used for treating fever due to affection of exogenous wind-heat or epidemic febrile disease, heatstroke, toxic heat, dysentery, carbuncle, furuncle, pharyngitis, and various infectious diseases. Modern researches prove that the honeysuckle contains pharmacological active ingredients such as chlorogenic acid and luteolin glycoside, has strong inhibition on various pathogenic bacteria such as hemolytic streptococcus, staphylococcus aureus and the like and upper respiratory infection pathogenic viruses and the like, can enhance immunity, resist early pregnancy, protect liver, resist tumor, diminish inflammation, relieve fever, stop bleeding (blood coagulation), inhibit intestinal absorption of cholesterol and the like, has very wide clinical application, and can be used for treating various diseases such as respiratory infection, bacillary dysentery, acute urinary system infection, hypertension and the like by being compatible with other medicines.
Fructus forsythiae: bitter and slightly cold. It enters lung, heart and small intestine meridians. Clear heat and remove toxicity, resolve swelling and dissipate nodulation. Can be used for treating carbuncle, cellulitis, scrofula, acute mastitis, erysipelas, wind-heat type common cold, early epidemic febrile disease, warm heat entering nutrient system, hyperpyrexia, polydipsia, coma, macula, and stranguria with heat. The fructus forsythiae is contained in the traditional Chinese medicine of the sore house holy drug, and has the functions of carbuncle, swelling, sore and toxin removing and phlegm nodule eliminating. Li shi zhen yu: fructus forsythiae is similar to human heart, and has two synthetic sheets, of which the kernel is very fragrant, and is also the principal drug of heart meridian and jueyin collateral qi system. All sores and ulcers with pain and itching belong to heart fire, so they are the twelve-channel sore family holy drug and they are also indicated for heat in the meridian qi system of shaoyang hands and feet and yangming hands. Modern pharmacological research shows that the forsythia has the function of resisting pathogenic microorganisms. The volatile oil emulsion of fructus forsythiae seed has inhibitory effect on gram-positive bacteria and gram-negative bacteria, and has inhibitory effect on Candida albicans and tropical candida, Beijing family 68-1 strain virus, Sendai strain virus, and Coxsackie B5 virus.
Rhubarb: bitter and cold. It enters spleen, stomach, large intestine, liver and pericardium meridians. Purge heat and unblock intestines, cool blood and remove toxicity, dispel stasis and dredge meridians. Used for treating excessive heat constipation, abdominal pain due to stagnation, dysentery, damp-heat jaundice, blood heat hematemesis, conjunctival congestion, pharyngeal swelling, acute appendicitis, abdominal pain, carbuncle, furuncle, amenorrhea due to blood stasis, traumatic injury, and scald due to hot water and fire; upper gastrointestinal hemorrhage.
Mirabilite: salty, bitter and cold. It enters stomach and large intestine meridians. Purge heat and relax bowels, moisten dryness and soften hard mass, clear fire and relieve swelling. Used for treating excessive heat constipation, abdominal pain due to stagnation, and intestinal abscess with swelling and pain; it is indicated for acute mastitis, hemorrhoid with swelling and pain.
Flavescent sophora root: bitter and cold. It enters heart, liver, stomach, large intestine and bladder meridians. Clear heat and dry dampness, kill parasites and induce diuresis. Can be used for treating dysentery with heat, hematochezia, jaundice, anuria, leucorrhea with red and white discharge, pudendal swelling, pruritus vulvae, eczema, skin pruritus, scabies, tinea, and leprosy; it can be used for treating trichomonas vaginitis.
Glabrous greenbrier rhizome: sweet, bland and mild. It enters liver and stomach meridians. Remove dampness, remove toxicity, and relieve joint pain. Can be used for treating damp-heat stranguria with turbid discharge, leukorrhagia, carbuncle swelling, scrofula, scabies, tinea, syphilis and limb spasm and arthralgia and myalgia caused by mercury poisoning.
Phellodendron bark: bitter and cold. It enters kidney and bladder meridians. Clear heat and dry dampness, purge fire and remove steam, remove toxicity and cure sore. Can be used for treating damp-heat dysentery, jaundice, leukorrhagia, stranguria caused by heat, tinea pedis, flaccidity, hectic fever due to yin deficiency, night sweat, spermatorrhea, pyocutaneous disease, toxic swelling, eczema, and pruritus.
Plantain seed: sweet and slightly cold. It enters liver, kidney, lung and small intestine meridians. Clearing away heat, promoting urination, eliminating dampness, treating stranguria, improving eyesight, and eliminating phlegm. Can be used for treating edema, heat stranguria, pain, summer-heat dampness, diarrhea, conjunctival congestion, swelling and pain, and cough due to phlegm-heat.
Herba artemisiae scopariae: bitter, pungent and slightly cold. It is entered into spleen, stomach, liver and gallbladder meridians. Clear damp-heat and alleviate jaundice. Can be used for treating jaundice, oliguria, eczema, and pruritus; infectious icteric hepatitis.
Herba Patriniae: pungent, bitter and cool. Enter stomach, large intestine and liver meridians. Clearing away heat and toxic material, eliminating carbuncle, expelling pus, promoting blood circulation and removing blood stasis. Can be used for treating abdominal pain, pain in chest and abdomen due to excessive heat and blood stasis, and puerperal abdominal pain due to intestinal carbuncle, pulmonary abscess, sore, carbuncle, and toxic swelling.
The preparation method comprises the following steps of (1) preparing broom cypress fruit: pungent, bitter and cold. It enters kidney and bladder meridians. Clear heat and promote diuresis, dispel wind and relieve itching. Can be used for treating difficult and painful urination, pruritus vulvae, leukorrhagia, rubella, eczema, and skin pruritus.
Fructus cnidii: pungent, bitter and warm; has little toxicity. It enters kidney meridian. Warming kidney and strengthening yang, drying dampness, dispelling wind and killing parasites. Can be used for treating sexual impotence, cold womb, leukorrhagia due to cold-dampness, and lumbago due to damp arthralgia; externally treating vulvar eczema and pruritus vulvae of women; trichomonas vaginitis.
Snake slough: salty, sweet and neutral. It enters liver meridian. Dispel wind, arresting convulsion, remove toxicity and remove nebula. Can be used for treating infantile convulsion, spasm, nebula, pharyngitis, sore throat, furuncle, and skin pruritus.
Cicada slough: sweet and cold in nature. It enters lung and liver meridians. Dispel wind and remove heat, relieve sore throat, promote eruption, remove nebula and relieve spasm. Can be used for treating wind-heat type common cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion, nebula, convulsion, and tetanus.
Herba schizonepetae: pungent and warm. It enters lung and liver meridians. Relieve exterior syndrome, dispel wind and promote eruption. Can be used for treating common cold, headache, measles, rubella, and initial stage of pyocutaneous disease. Stir-baked into charcoal is indicated for hematochezia, metrorrhagia and metrostaxis and postpartum anemic fainting.
Wind prevention: pungent, sweet and warm. It enters bladder, liver and spleen meridians. Relieve exterior syndrome, dispel wind, subdue dampness and stop spasm. Can be used for treating common cold, headache, rheumatalgia, rubella, pruritus, and tetanus.
Radix angelicae: pungent and warm. Enter lung, spleen and stomach meridians. Dispel wind, dry dampness, resolve swelling and alleviate pain. It can be used for treating headache, supercilium pain, odontalgia, nasosinusitis, cold-dampness, abdominal pain, intestinal wind, hemorrhoid, leucorrhea with red and white discharge, carbuncle, skin ulcer, pruritus, scabies, and tinea.
Houttuynia cordata: pungent and slightly cold herbs enter lung meridian. Clear heat and remove toxicity, induce diuresis and alleviate edema. Treating pneumonia, lung abscess, dysentery, malaria, edema, gonorrhea, leucorrhea, carbuncle, swelling, hemorrhoid, rectocele, eczema, alopecia, scabies and tinea.
Tamarix chinensis: sweet and salty, neutral. Enters lung, stomach and heart channels, dispels wind, relieves exterior syndrome, promotes urination and detoxifies. It is used to treat measles, rubella, cough, asthma, rheumatic osteodynia, etc. The "Dong Yi Bao Jian" (eastern medicine and treasures) of "Tamarix chinensis is used for treating scabies and tinea and all malignant sores". Modern pharmacological research shows that tamarix chinensis has obvious cough relieving, antibacterial, antipyretic and hepatitis resisting effects.
Herba ephedrae: pungent, slightly bitter and warm. It enters lung and bladder meridians. Induce sweating and dispel cold, ventilate lung and relieve dyspnea, induce diuresis to alleviate edema. Can be used for treating common cold due to wind-cold, chest distress, cough, and edema; bronchial asthma. Honey Chinese ephedra can moisten lung and relieve cough. It is often indicated for exterior syndrome, asthma and cough.
Cassia twig: pungent, sweet and warm. It enters heart, lung and bladder meridians. Induce sweating to relieve muscles, warm and dredge meridians, strengthen yang to transform qi, and smooth the flow of qi. Can be used for treating wind-cold type common cold, abdominal psychroalgia, blood cold amenorrhea, arthralgia, phlegm retention, edema, palpitation, and galloping.
Almond: bitter and slightly warm; has little toxicity. Enter lung and large intestine meridians. Dispel phlegm and relieve cough, relieve dyspnea, moisten intestines. It is indicated for cough due to exogenous pathogenic factor, dyspnea, throat impediment, constipation due to intestinal dryness.
Bulbus Fritillariae Cirrhosae: bitter and sweet in taste, slightly cold in nature; entering lung and heart meridians; moistening and purging, descending and micro-liter; has effects of clearing heat, eliminating phlegm, moistening lung, relieving cough, resolving hard mass and relieving swelling; it can be used for treating chronic cough due to asthenia, dry cough due to lung heat, lung abscess with pus, scrofula, tuberculosis, mammary abscess, and sore.
Thunberg fritillary bulb: bitter and cold. It enters lung and heart meridians. The functions are mainly used for clearing heat and resolving masses, eliminating phlegm and relieving cough, and is used for wind-heat affecting lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula and sore toxicity.
Rhizoma atractylodis: pungent, bitter and warm. It enters spleen, stomach and liver meridians. Dry dampness and invigorate spleen, dispel wind and cold, improve vision. Can be used for treating abdominal distention, diarrhea, edema, tinea pedis, paralysis 36484m, rheumatalgia, common cold due to wind-cold evil, and night blindness.
Chinese yam: sweet, mild and nontoxic. It enters spleen, lung and kidney meridians. Tonify spleen and stomach, promote the production of body fluid and nourish lung, tonify kidney and astringe essence. Can be used for treating spleen deficiency, anorexia, chronic diarrhea, lung deficiency, cough, asthma, spermatorrhea, leukorrhagia, frequent micturition, and diabetes due to deficiency heat. The bran-parched rhizoma Dioscoreae has effects of invigorating spleen and invigorating stomach. Can be used for treating spleen deficiency, anorexia, diarrhea, loose stool, and leukorrhagia.
White hyacinth bean: sweet and warm. It enters spleen and stomach meridians. To invigorate the spleen, resolve dampness, regulate the middle warmer and relieve summer heat. Can be used for treating weakness of spleen and stomach, anorexia, diarrhea, leukorrhagia, summer heat, dampness, vomiting and diarrhea, chest distress, and abdominal distention.
Chinese prickly ash: pungent flavor and warm nature. It enters spleen, stomach and kidney meridians. Warming the middle-jiao to dispel cold, removing dampness, relieving pain, killing parasites and removing fishy smell. It is used to treat retention of food and drink, psychroalgia of heart and abdomen, emesis, hiccup, cough, adverse qi, anemofrigid-damp arthralgia, diarrhea, dysentery, hernia pain, toothache, ascariasis, enterobiasis, pudendal pruritus, sore, and scabies.
Raw licorice root: sweet and neutral. It enters heart, lung, spleen and stomach meridians. Invigorating spleen and replenishing qi, clearing away heat and toxic material, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the drugs. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, swelling, sore, and drug toxicity and strong nature.
The disease treatment mechanism of the invention is as follows: the invention takes the bupleurum, the curcuma, the angelica and the red paeony root to enter liver channels of foot jueyin, soothes liver and relieves depression, and takes various medicines to reach focus. Honeysuckle, forsythia, rhubarb, mirabilite, radix sophorae flavescentis and phellodendron bark are used for clearing heart-fire, and smilax glabra, plantain seed, oriental wormwood, herba patriniae, broom cypress fruit and common cnidium fruit are used for purging damp-heat in liver and gallbladder, eliminating dampness and disinsection and eliminating damp-heat internal environment parasitized by virus. Cicada slough, snake slough, herba schizonepetae, radix sileris, radix angelicae, houttuynia cordata, tamarix chinensis, ephedra, cassia twig and almond among the ministerial drugs promote viruses to float on the surface of the skin from the muscle, and the virus is promoted to be new, removed the putrefaction and engendered, subsided swelling and cured sore; bulbus Fritillariae Cirrhosae and Bulbus Fritillariae Thunbergii soften wart and promote discharge, dissipate stagnation and dredge collaterals. The Chinese yam, the rhizoma atractylodis and the white hyacinth bean are adjuvant drugs, play a role in strengthening spleen, removing dampness and relieving the virus internal growth environment of moist heat of the pudendum, and promote the pudendum to be dry. The guiding drug is the cold and cool drug in the formula prepared by the pepper and the liquorice, the pepper prevents the damage of the yang qi of the organism, plays the roles of warming yang, killing insects, strengthening and expelling toxin, and the liquorice not only can harmonize the properties of the drugs, but also can detoxify and relieve the discomfort symptom of the pudendum. The traditional Chinese medicine pill has clear treatment rules and reasonable compatibility, has the efficacies of eliminating dampness and killing insects, clearing liver and expelling toxin, reducing swelling and curing sores, cooling blood and removing blood stasis, removing necrosis and promoting granulation and the like, has good curative effect, quick response, convenient administration, safety and reliability, and can achieve the effect of treating both symptoms and root causes.
The invention has the beneficial effects that:
the pill agent of the invention is a natural pure traditional Chinese medicine pill, adopts the comprehensive synergistic effect of thirty-three traditional Chinese medicines of bupleurum, curcuma aromatica, angelica, red paeony root, honeysuckle, forsythia, rhubarb, mirabilite, sophora flavescens, glabrous greenbrier rhizome, phellodendron, plantain seed, oriental wormwood, dahurian patrinia herb, belvedere fruit, common cnidium fruit, snake slough, cicada slough, fineleaf schizonepeta herb, divaricate saposhnikovia root, dahurian angelica root, heartleaf houttuynia herb, tamarisk, ephedra, cassia twig, almond, bulbus fritillariae cirrhosae, thunberg fritillary bulb, rhizoma atractylodis, yam, white hyacinth bean, pepper and raw liquorice with specific dosage, has the efficacies of eliminating dampness and killing insects, clearing heat and expelling, can effectively treat both principal and secondary aspects of diseases of condyloma acuminatum patients, has high cure rate, low recurrence rate, small side effect on human bodies, simple preparation process and convenient administration, and is particularly suitable for treating condyloma acuminatum patients.
In order to illustrate the efficacy of the invention in treating condyloma acuminatum, 215 patients with condyloma acuminatum who are diagnosed are selected for clinical observation, and the observation results are as follows:
1. case selection
215 patients with condyloma acuminatum are clinically diagnosed, wherein 101 male patients are aged 17-54 years, the average age is 38.3 years, the half year with the shortest disease course and the 5 years with the longest disease course; 114 women aged 16-65 years, with an average age of 41.8 years, the shortest disease course of one month and the longest disease course of 7 years.
The patients with condyloma acuminatum were randomly divided into 107 treatment groups of 50 men and 57 women and 108 control groups of 51 men and 57 women. The disease course and the severity of symptoms of the two groups of cases of the treatment group and the control group are basically consistent, have no obvious difference and are comparable.
2. Method of treatment
The pills are orally taken by a treatment group, are taken with warm boiled water, are respectively taken 1 pill after 1 hour every day in the morning, in the middle of the day and at night, and 30 days are 1 course of treatment.
In the control group, 0.5% podophyllotoxin tincture (also called foenum graecum tincture) is applied externally to wart body, and recombinant human interferon intramuscular injection therapy is combined according to the state of illness, and 30 days is 1 course of treatment.
3. Determination of therapeutic effect
And (3) healing: the skin damage is completely disappeared, the clinical symptoms are disappeared, the wart body is completely disappeared, the histopathological examination is normal, and the acetic acid white test is negative.
The method has the following advantages: the clinical symptoms are obviously improved, the number of warts is reduced by more than 30 percent, and the acetic acid white test is positive.
And (4) invalidation: clinical symptoms have no obvious change, and papilloma hyperplasia, hollow cells at the upper part of a spinous layer and a granular layer and capillary vessel hyperplasia in a dermal papilla are mainly seen under a microscope; the aceto-white test is positive.
4. As a result: the experiment totals 215 cases, wherein 107 cases of the treatment group and 108 cases of the control group are treated, and the curative effect results after the treatment group and the control group are respectively treated for 2 courses are shown in table 1.
Table 1: therapeutic results of the treatment groups and the control group
The curative effect results of the treatment group and the control group show that the total effective rate of the invention for treating the patients suffering from condyloma acuminatum reaches 100 percent, the cure rate reaches 94.3 percent, and the total effective rate and the cure rate are both obviously higher than those of the control group.
The incidence of adverse events in the treatment group and the control group during the treatment period is shown in Table 2
Table 2: incidence of adverse reactions between treatment group and control group
Recurrence of the disease: after clinical basic cure, because a certain case state still exists in the body, if the body is decompensated or infected again after a period of time, the disease is easy to relapse, and the relapse rate of the treatment group and the control group is shown in table 3.
TABLE 3 relapse rates in different time periods for the treatment group and the control group
The specific implementation mode is as follows:
the invention is further illustrated by the following examples, which are not intended to limit the scope of the invention.
Weighing the traditional Chinese medicine raw materials of the embodiments according to the parts by weight, uniformly mixing, heating and sterilizing for 4 minutes by using microwaves, then crushing the thirty-three traditional Chinese medicine raw materials into fine powder by using a crusher, sieving by using a 100-mesh sieve, drying, preparing pills by using 100 parts of sieved fine powder and 100 parts of refined honey as adhesives, further drying and polishing the pills to obtain the finished traditional Chinese medicine pills for treating condyloma acuminatum.
Examples of typical cases are:
1. a certain Wang, a man, a 20 year old and unmarried, the initial diagnosis is carried out in 2013 in 1 month and 20 days, the patient finds that the glans, the penis, the vulva and the perianal region have neoplasms, no pain and itch and other discomforts 3 days ago, the patient is led to a certain Shenzhen hospital to see a doctor, and the physical examination is carried out: there are substantial convex vegetation on glans, penis and perianal, rice grain to soybean size, rough and granular surface, acetic acid experiment (+), bleeding occasionally. And (-). In Shenzhen, the wart atrophy is resolved by microwave operation under local anesthesia. However, after one month, new lesions continue to grow outward from the root of the original wart. After the medicine is taken for 1 month, the glans, the penis and the perianal neoplasm are gradually reduced and shrunk, the local foreign body sensation is reduced, the glans, the penis and the perianal neoplasm disappear after the medicine is continuously taken for 2 months, and the acetic acid experiment (-) reaches the clinical cure standard. The medicine is continuously taken for 2 weeks to consolidate the curative effect, and no relapse occurs in 2015, 6 months and 19 days of follow-up.
2. Zhang, woman, 56 years old, dissimilarity, in the first visit of 7, month 14 in 2015, the patient found that there were substantial convex excrescences in the vulva and perianal area one month after some unclean intercourse, and in some hospitals the laser excision treatment was performed, and the patient relapsed and had increased volume less than one month after excision, so the treatment with laser three times, and the patient was decided to use the traditional Chinese medicine treatment. Through inspection, 8 vulva and perianal neoplasms have handles, are soft in quality and free of touch pain, have sexual intercourse discomfort and are diagnosed as condyloma acuminatum, the traditional Chinese medicine dialectically considers that damp-heat toxin gathers in the lower jiao, after the vulva and perianal neoplasms are taken for 5 weeks, the vulva and perianal neoplasms become dry, and after the vulva and perianal neoplasms are continuously taken for 4 weeks, the neoplasms are atrophied and shed, and the skin of the perianal vulva is smooth and has no obvious boundary with the surrounding skin. Has reached the clinical cure standard. No recurrence occurred in 2016, 7, 18 days of follow-up.
3. In a certain forest, male, 37 years old, married, and in the initial diagnosis date, in 2017, 10 and 28 days old, when taking a bath once, the creatures with different sizes from 4 soybeans to red dates are found unintentionally at 3 points, 5 points, 8 points and 11 points of the perianal area, and are in the shapes of cauliflower and papilloma, white or light red, and some skin lesions have broken surfaces and purulent secretion. The multifunctional electric ion operation therapeutic machine is used in a certain hospital in Guangdong for removing therapy, and then antibiotic ointment is coated on the local part of the body, and the body is bound up. The antibiotic ointment is applied every day, the growth-promoting substances disappear after ten days of treatment, and the growth-promoting substances grow from the roots after the second month of relapse. The Chinese traditional medicine treatment is applied, the diagnosis of damp-heat toxin stasis in the lower energizer is made through dialectical treatment, and the treatment method adopts the direct oral Chinese traditional medicine to expel toxin. After the medicine is taken for 2 weeks, a plurality of growth-promoting organisms grow out from the root part around the anus, the medicine is continuously taken for 1 month, the growth-promoting organisms grow out firstly subsequently, and then the atrophy disappears in ten days. The medicine is continuously taken for 2 weeks to consolidate the curative effect, no proliferation organisms appear around the anus, the clinical cure is realized, and no relapse occurs in follow-up visits to the present.
Claims (1)
1. A traditional Chinese medicine pill for treating condyloma acuminatum is characterized in that: the traditional Chinese medicine is prepared from the following traditional Chinese medicine raw materials in parts by weight:
bupleuri radix 50, Curcmae rhizoma 80, Angelicae Gigantis radix 100, and radix Paeoniae Rubra 80
Honeysuckle flower 50, weeping forsythia 80, rhubarb 50 and mirabilite 60
Radix Sophorae Flavescentis 100, rhizoma Smilacis Glabrae 100, cortex Phellodendri 50, semen plantaginis 30
Herba Artemisiae Scopariae 30 herba Patriniae 40 fructus Kochiae 40 fructus Cnidii 40
40 snake slough, 40 cicada slough, 40 schizonepeta, 50 divaricate saposhnikovia root and 40
Radix Angelicae Dahuricae, herba Houttuyniae, 60 ramulus et folium Tamaricis, 80 herba Ephedrae, 50
Cassia twig 50 apricot kernel 60 Sichuan fritillary bulb 60 Zhejiang fritillary bulb 80
50 rhizoma atractylodis, 60 Chinese yam, 80 white hyacinth bean and 50 zanthoxylum bungeanum
Radix Glycyrrhizae 30
Weighing the raw materials of thirteen traditional Chinese medicines including radix bupleuri, radix curcumae, angelica sinensis, radix paeoniae rubra, honeysuckle, fructus forsythiae, rheum officinale, mirabilite, radix sophorae flavescentis, rhizoma smilacis glabrae, cortex phellodendri, semen plantaginis, oriental wormwood, dahurian patrinia herb, fructus kochiae, fructus cnidii, periostracum serpentis, periostracum cicadae, herba schizonepetae, radix sileris, radix angelicae, houttuynia cordata, tamarix chinensis, ephedra, cassia twig, almond, bulbus fritillariae cirrhosae, fritillaria thunbergii, rhizoma atractylodis, Chinese yam, white hyacinth beans, pepper and raw liquorice according to the weight parts, mixing, heating and sterilizing for 4 minutes by using microwaves, then crushing the raw materials of the thirty-three traditional Chinese medicines into fine powder by using a crusher, sieving by using a 100-mesh sieve, drying, sieving the.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1197660A (en) * | 1997-04-28 | 1998-11-04 | 王陕清 | Medicine 'Youxiaojing' for eliminating wart |
| CN101120986A (en) * | 2006-08-09 | 2008-02-13 | 林朝文 | Body-clearing itching-relieving liquid |
| CN105213908A (en) * | 2014-06-27 | 2016-01-06 | 费俊 | Be used for the treatment of the fumigation and washing agent of condyloma acuminatum of anus |
-
2018
- 2018-04-18 CN CN201810346786.0A patent/CN108273009B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1197660A (en) * | 1997-04-28 | 1998-11-04 | 王陕清 | Medicine 'Youxiaojing' for eliminating wart |
| CN101120986A (en) * | 2006-08-09 | 2008-02-13 | 林朝文 | Body-clearing itching-relieving liquid |
| CN105213908A (en) * | 2014-06-27 | 2016-01-06 | 费俊 | Be used for the treatment of the fumigation and washing agent of condyloma acuminatum of anus |
Non-Patent Citations (4)
| Title |
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| 中药内服、外洗治疗***93例;杨洪刚;《中医药信息》;20031231(第03期);第45页 * |
| 中药复方顽疣净对小鼠免疫器官重量和淋巴细胞转化的影响;刘源等;《湖北中医学院学报》;20060331(第01期);第25-26页 * |
| 消风散证治举隅;李爱君;《现代中西医结合杂志》;20010331(第05期);第438-439页 * |
| 祛湿除疣汤治疗***尖锐湿庞42例;叶秀春等;《海峡药学》;19951231(第03期);第70-71页 * |
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