CN108267183A - A kind of device and method of synchro measure breathing gas flow and ingredient - Google Patents
A kind of device and method of synchro measure breathing gas flow and ingredient Download PDFInfo
- Publication number
- CN108267183A CN108267183A CN201710003931.0A CN201710003931A CN108267183A CN 108267183 A CN108267183 A CN 108267183A CN 201710003931 A CN201710003931 A CN 201710003931A CN 108267183 A CN108267183 A CN 108267183A
- Authority
- CN
- China
- Prior art keywords
- signal
- unit
- processing unit
- infrared
- breathing gas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000029058 respiratory gaseous exchange Effects 0.000 title claims abstract description 71
- 238000000034 method Methods 0.000 title claims abstract description 23
- 239000004615 ingredient Substances 0.000 title claims abstract description 20
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims abstract description 100
- 238000012545 processing Methods 0.000 claims abstract description 73
- 229910002092 carbon dioxide Inorganic materials 0.000 claims abstract description 50
- 239000001569 carbon dioxide Substances 0.000 claims abstract description 50
- 230000002411 adverse Effects 0.000 claims abstract description 21
- 230000008054 signal transmission Effects 0.000 claims abstract description 21
- 238000012360 testing method Methods 0.000 claims abstract description 20
- 230000007613 environmental effect Effects 0.000 claims abstract description 15
- 230000004199 lung function Effects 0.000 claims abstract description 14
- 238000005259 measurement Methods 0.000 claims description 27
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 17
- 230000003750 conditioning effect Effects 0.000 claims description 13
- 230000000644 propagated effect Effects 0.000 claims description 10
- 238000010521 absorption reaction Methods 0.000 claims description 7
- 230000003321 amplification Effects 0.000 claims description 6
- 238000001514 detection method Methods 0.000 claims description 6
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 238000002329 infrared spectrum Methods 0.000 claims description 3
- 238000004806 packaging method and process Methods 0.000 claims description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 2
- 229910052799 carbon Inorganic materials 0.000 claims description 2
- 230000010354 integration Effects 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims description 2
- 238000004088 simulation Methods 0.000 claims description 2
- 238000012546 transfer Methods 0.000 claims description 2
- 241000790917 Dioxys <bee> Species 0.000 claims 1
- 238000007781 pre-processing Methods 0.000 claims 1
- 230000003519 ventilatory effect Effects 0.000 abstract description 15
- 230000005540 biological transmission Effects 0.000 abstract description 7
- 238000003745 diagnosis Methods 0.000 abstract description 6
- 239000003814 drug Substances 0.000 abstract description 2
- 238000010586 diagram Methods 0.000 description 10
- 230000006870 function Effects 0.000 description 10
- 238000005516 engineering process Methods 0.000 description 5
- 238000007689 inspection Methods 0.000 description 5
- 238000009613 pulmonary function test Methods 0.000 description 5
- 230000000241 respiratory effect Effects 0.000 description 5
- 238000002604 ultrasonography Methods 0.000 description 5
- 238000005070 sampling Methods 0.000 description 4
- 230000001360 synchronised effect Effects 0.000 description 4
- 238000009423 ventilation Methods 0.000 description 4
- 239000000523 sample Substances 0.000 description 3
- 238000002835 absorbance Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 230000002123 temporal effect Effects 0.000 description 2
- 208000030090 Acute Disease Diseases 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 1
- 206010011409 Cross infection Diseases 0.000 description 1
- 241001269238 Data Species 0.000 description 1
- 206010014561 Emphysema Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 208000006193 Pulmonary infarction Diseases 0.000 description 1
- 208000004756 Respiratory Insufficiency Diseases 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000007575 pulmonary infarction Effects 0.000 description 1
- 238000011897 real-time detection Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 201000004193 respiratory failure Diseases 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000002627 tracheal intubation Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F1/00—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow
- G01F1/66—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow by measuring frequency, phase shift or propagation time of electromagnetic or other waves, e.g. using ultrasonic flowmeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/3504—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Analytical Chemistry (AREA)
- Fluid Mechanics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Electromagnetism (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring Volume Flow (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
Abstract
The present invention relates to a kind of synchro measure breathing gas flow and the device and method of ingredient, device includes：Ultrasonic flow transducer subelement, in infrared End-tidal carbon dioxide sensor subunits, environmental condition test cell, drive control and signal processing unit, signal transmission unit, power supply unit.Method includes：Downstream propagation times T is measured with ultrasonic flow transducer subelementfWith adverse current propagation time Tb；The REAL TIME INFRARED THERMAL IMAGE intensity signal of infrared End-tidal carbon dioxide sensor subunits acquisition in utilization；The content C of the flow of breathing gas, real-time carbon dioxide is calculated using drive control and signal processing unit.The method of the present invention is implemented synchronously to measure the ventilatory function and ventilatory of lung function in same integrated sensor, and diagnosis efficiency is greatly improved, and the application in tele-medicine is realized by wireless data transmission.
Description
Technical field
The present invention relates to breathing gas flow and composition measurement field, specifically a kind of synchro measure breathing gas stream
The device and method of amount and ingredient.
Background technology
Pulmonary function test includes ventilatory function, ventilatory, respiratory regulation function and pulmonary circulatory function etc..Respiratory flow measures
Amount is widely used in pulmonary function test field.Basic pulmonary function test is a kind of physical inspection method, passes through simple respiratory flow
Measurement can obtain some basic lung function parameters such as：The ventilatory functions index such as capacity performance index, ventilation index, airway resistance.
Pulmonary function test can be with the common chronic lung disease of screening such as：Pulmonary emphysema, asthma, Chronic Obstructive Pulmonary Disease.It is this to measure only
It can check ventilatory function.
Most of lung function instrument flow measurement is measured using turbine, hot line or differential pressure pickup, precision, reliable
Property, stabilization and repeatability, safety, use cost cannot all meet the clinical requirement to pulmonary function test instrument performance.Ultrasound
Gas flow measurement technology can then overcome as above shortcoming, and with following features：Precision is high；It is reliable long-lived without moving parts；Stream
Measurements are by environmental parameter such as gas component, and pressure, temperature, humidity influence is small, reproducible；Stability is good, remove from through
The trouble often proofreaded；Easily disinfection avoids cross-infection.
The diffusion index measured needed for checking ventilatory must then use being tested with disperse for complex and expensive
The special instrument of function.Which limits the extensive uses of ventilatory inspection.Market in urgent need one kind is for advanced more multigroup
Close the sensing technology that the lung function instrument of function uses：Can be convenient, it is reliable and low cost to measure flow and predominant gas simultaneously
The sensor of ingredient.The lung function instrument established by means of this sensing technology is made in primary check while obtains ventilation work(
Energy, ventilatory data are possibly realized, and screening and diagnosis efficiency is greatly improved, and reduce doctors and patients' cost.
Last carbon dioxide (ETCO is exhaled in middle infrared absorption measurement2) acute disease field is widely used at present, such as：Anesthesia machine and
The security application of lung ventilator, all kinds of respiratory insufficiencies, CPR, serious shock, heart failure and pulmonary infarction determine general anesthesia
The position of endotracheal intubation.In addition to this ETCO2Real time detection performance and obtain very valuable parameter can realize soon
Speed, accurately, safety, the inspection of noninvasive ventilatory, with reference to ventilatory function inspection, patient diagnosis is provided it is more advanced,
Tool accurately and quickly.But it there is no such outpatient service instrument and application at present.
In view of ultrasonic respiratory flow measures and ETCO2It belongs to non-intruding form real―time precision measurment means and provides respectively
Most there are the ventilatory function of diagnosis reference value, the information of ventilatory, the two combination can then open up completely new diagnosis research
Neighborhood and practical approach.
Since respiratory ventilation is synchronous and occur in succession in breath cycle with ventilation, the two temporal associativity is extremely strong,
Abundant information.Information of the further investigation with time correlation is expectable to be inferred to than any method is used alone more and can
The diagnostic message leaned on.This proposes higher requirement for sensor simultaneously：Two kinds of sensors must measure in same device
The necessary time high-resolution of data sampling, measurement data sampling must occur, not interfere with each other, collected data must be real-time simultaneously
Processing, two groups of real time datas that treated must be passed with the fixed and minimum time difference with most plain mode to central processing section
It is defeated.
It there is no individual at present, mechanism or company have the technology that can meet requirements above or product to occur.The present invention provides
Effective solution and method.
Invention content
For above-mentioned shortcoming in the prior art, the technical problem to be solved in the present invention is to provide a kind of synchronizations
The device and method of breathing gas flow and ingredient is measured, using ultrasonic flow rate sensing and the integrated knot of middle infrared carbon dioxide sensing
The method of structure, the processing of time interleaving synchronized sampling and transmission obtains high time resolution and high-precision breathing gas flow and two
Carbon component real-time synchronization information is aoxidized, realizes the unified measurement of more than one main lung function.
Present invention technical solution used for the above purpose is：A kind of synchro measure breathing gas flow and ingredient
Device and method.
A kind of device of synchro measure breathing gas flow and ingredient, including：
Ultrasonic flow transducer unit connects drive control and signal processing unit, for measuring downstream propagation times Tf
With adverse current propagation time Tb, and export to drive control and signal processing unit；
In infrared End-tidal carbon dioxide sensor unit, drive control and signal processing unit are connected, for adopting in real time
Collect End-tidal carbon dioxide infrared intensity signal, and export to drive control and signal processing unit；
Environmental condition test cell connects drive control and signal processing unit, for measuring temperature, pressure, humidity letter
Number, and export to drive control and signal processing unit；
Drive control and signal processing unit, connection ultrasonic flow transducer subelement, in infrared End-tidal carbon dioxide
Sensor subunits, environmental condition test cell, signal transmission unit, for driving and controlling said units work, receive
State the signal and data of unit output；It is additionally operable to the downstream propagation times T receivedfWith adverse current propagation time TbCalculate breathing
The flow of gas and the content C that real-time carbon dioxide is calculated according to the infrared intensity signal of reception；Again by breathing gas
Flow and the content C of carbon dioxide is exported to signal transmission unit in real time；
Signal transmission unit connects drive control and signal processing unit, is turned using time zone interleaved code packaging method
The flow of breathing gas and the content C of real-time carbon dioxide are sent out to lung function instrument host or Internet data center；
Power supply unit connects said units, for providing working power for said units.
The ultrasonic flow transducer subelement, including：
Tested gas measurement passageway, for guiding tested breathing gas；
Two sonacs, it is oblique be placed in measure gas channel both ends, between distance be Lu, and sonac
The axis angle of axis and tested gas measurement passageway is θ, for emitting ultrasonic signal, receiving ultrasonic echo signal；Institute
State two sonac alternate emissions and received ultrasonic signal；
Power drive unit, connection drive control and signal processing unit, two sonacs, timing units；For
Under the control of drive control and signal processing unit, alternately control two sonac transmittings or receive excusing from death wave letter
Number, while output pulse signal driving timing unit works；
The preliminary conditioning unit of signal connects two sonacs；The ultrasonic signal of sonac output is filtered
Wave, shaping and average treatment are then output to level discriminator unit；
Level discriminator unit, connection signal conditioning unit；Thresholding detection is carried out to the signal of signal condition unit output, when
Triggering timing module stops timing when signal reaches predetermined threshold value；
Timing unit connects level discriminator unit；For recording ultrasonic pulse downstream propagation times TfWhen being propagated with adverse current
Between Tb, and export to interface unit；
Interface unit, connection drive control and signal processing unit, timing unit；For exporting downstream propagation times TfWith
Adverse current propagation time TbTo drive control and signal processing unit；
Infrared End-tidal carbon dioxide sensor subunits in described, including：
Middle infrared transmitter, trepanning is mounted on tested gas measurement passageway outer wall, and its launch window face is exposed to
In breathing gas；For emitting pulse modulated infrared radiation signal to tested gas；
Infrared detector, trepanning is mounted on tested gas measurement passageway outer wall, and its reception window side is exposed to and exhales
In air-breathing body, and it is staggered relatively with middle infrared transmitter；For acquiring the infrared intensity signal in tested gas in real time；
Power drive unit connects drive control and signal processing unit, middle infrared transmitter, lock phase amplification module；With
Under the control in drive control and signal processing unit, infrared transmitter works in transmitting pulse signal driving, exports simultaneously
Synchronous control signal gives lock phase amplifying unit；
Phase amplifying unit is locked, connects infrared detector；Processing is amplified for the infrared intensity signal to reception；
The preliminary conditioning unit of signal, connection lock phase amplifying unit；For being integrated to infrared intensity amplified signal
And average treatment, it is then output to level discriminator unit；
Level discriminator unit, the preliminary conditioning unit of connection signal；For carrying out level detection, Ran Houding to received signal
When export REAL TIME INFRARED THERMAL IMAGE intensity signal to interface unit；
Interface unit connects drive control and signal processing unit；For forwarding REAL TIME INFRARED THERMAL IMAGE intensity signal to drive
Dynamic control and signal processing unit；
The environmental condition test cell includes：Temperature sensor, pressure sensor, humidity sensor；Each biography
There are driving and signal condition unit inside sensor；For acquiring, improving temperature signal, pressure signal, moisture signal and be sent to
Drive control and the control in signal processing unit and digital signal center processing unit, the conditioning include amplification, filtering, zero
Point is stablized.
The drive control includes with signal processing unit：
Ultrasonic flow transducer driving unit, for be sonac provide pulse drive signal；
In infrared End-tidal carbon dioxide sensor driving unit, for middle infrared transmitter provide pulsed drive letter
Number；
Ultrasonic flow transducer interface unit, for forwarding downstream propagation times TfWith adverse current propagation time TbAt center
Manage unit；
In infrared End-tidal carbon dioxide sensor interface unit, mould is carried out to the REAL TIME INFRARED THERMAL IMAGE intensity signal of reception
Intend pretreatment, then export to center processing unit；The simulation pretreatment includes amplification, filtering, zero point stability, is used to implement mould
Number conversion；
Clock unit provides simultaneously operating signal to whole device；
Center processing unit, to carry number and the microprocessor of analog interface, for the downstream propagation times to reception
TfWith adverse current propagation time TbIt calculates the flow of breathing gas and is calculated according to the REAL TIME INFRARED THERMAL IMAGE intensity signal of reception real
When carbon dioxide content C；
Environmental condition test interface unit, for being believed using the method for multi-point calibration temperature signal, pressure signal, humidity
It number carries out calculating compensation and export to center processing unit；
Communication interface unit, connection signal transmission unit；For exporting the flow of breathing gas and real-time carbon dioxide
Content C is to signal transmission unit；
Power interface unit, for providing working power for said units.
The signal transmission unit includes：
Wire signal transmission unit, be used to implement with the wired data transfer of lung function instrument host and ask for power supply supply；
Wireless signal transmitting unit is used to implement wireless data exchange and wireless controlled with lung function instrument host or internet
System.
The power supply unit includes：
Power supplied locally unit is chargeable battery and its charging circuit；
External wired power supply unit, including dispatch from foreign news agency detecting, conditioning and protection circuit；For connecting external power supply；
Power Management Unit, for being managed to power supplied locally unit and external wired power supply unit.
A kind of method of synchro measure breathing gas flow and ingredient, includes the following steps：
Ultrasonic wave downstream propagation times T is measured by ultrasonic flow transducer unitfWith adverse current propagation time Tb, and export
It is used to calculate the flow of breathing gas to drive control and signal processing unit；
Infrared End-tidal carbon dioxide sensor subunits measure infrared intensity signal in, and export to driving
Control is used to calculate the content C of real-time carbon dioxide with signal processing unit；
The drive control calculates the flow of breathing gas with signal processing unit, includes the following steps：
S1：Downstream propagation times T when ultrasonic signal is propagated in breathing gasf, adverse current propagation time TbIt substitutes into public
Formula (1) calculates breathing gas velocity of sound Sr：
S2：Time difference for being transmitted in breathing gas according to ultrasonic wave, the velocity of sound, breathing gas stream can be obtained according to formula (2)
Fast u：
S3：According to breathing gas flow velocity u and pipeline sectional area A is measured, breathing gas flow Q can be obtained according to formula (3)：
Q=u × A (3)
Wherein, downstream propagation times TfFor ultrasonic signal propagation direction it is consistent with airflow direction when ultrasonic wave it is super at two
The time propagated between raw sensor, adverse current propagation time TbFor ultrasonic signal propagation direction it is opposite with airflow direction when ultrasound
The time that wave is propagated between two excusing from death sensors；Ultrasonic measurement distance is distance L between two sonacsuIt is fixed
Value, ultrasonic sensor axis are θ with tested gas measurement passageway axis angle.
The content C that the drive control calculates real-time carbon dioxide with signal processing unit includes the following steps：
According to infrared spectrum theory and Lambert-beer's law：
I=I0exp(-KCLR) (4)
Wherein, I infrared lights pass through the light intensity after TCH test channel, I0Enter the light intensity before TCH test channel for infrared light, C is exhales
Inhale the content of carbon dioxide in gas, LRFor the length of transmitted light path, K is absorption coefficient, and K and temperature, pressure, humidity
Signal is related.
The invention has the advantages that and advantage：
The present invention implements the principal functional parame-ters classification of synchronous two lung function of measurement in same integrated sensor
That is diagnosis efficiency is greatly improved in ventilatory function and ventilatory, reduces medical treatment cost and can realize that wireless data transmission carries out
Mobile or tele-medicine.
Description of the drawings
Fig. 1 is the system structure diagram of the present invention；
Fig. 2 is the ultrasonic flow transducer sub-unit structure schematic diagram in present system；
Fig. 3 be present system in infrared End-tidal carbon dioxide sensor unit structure schematic diagram；
Fig. 4 (a) is integrated ultrasonic flow rate infrared End-tidal carbon dioxide sensor detection in present system
Part body principle schematic；
Fig. 4 (b) is to include integrated ultrasonic flow rate infrared End-tidal carbon dioxide sensor in present system
The practical schematic diagram of probe portion mechanism, ultrasound occur with infrared survey in same plane；
Fig. 4 (c) is to include integrated ultrasonic flow rate infrared End-tidal carbon dioxide sensor in present system
The practical schematic diagram of probe portion mechanism, ultrasound occur with infrared survey in orthogonal plane；
Fig. 5 is drive control and signal processing sub-unit structure schematic diagram in present system；
Fig. 6 is the signal transmission unit structure diagram in present system；
Fig. 7 is the data encoding transmission structure schematic diagram that the signal transmission unit in present system uses；
Fig. 8 is the power supply unit structure diagram in present system.
Specific embodiment
The present invention is described in further detail with reference to the accompanying drawings and embodiments.
As shown in Figure 1, the device of a kind of synchro measure breathing gas flow and ingredient, including ultrasonic flow transducer list
Member, in infrared End-tidal carbon dioxide sensor unit, environmental condition test cell, drive control and signal processing unit, letter
Number transmission unit, power supply unit.Ultrasonic flow transducer unit, for measuring downstream propagation times TfWith adverse current propagation time Tb；
In infrared End-tidal carbon dioxide sensor unit, for acquiring REAL TIME INFRARED THERMAL IMAGE intensity signal；Environmental condition test cell,
For measuring temperature, pressure, moisture signal；Drive control and signal processing unit, for driving and controlling said units to work,
Receive the signal and data of said units output；It is additionally operable to the downstream propagation times T receivedfWith adverse current propagation time TbMeter
It calculates the flow of breathing gas and the content C of real-time carbon dioxide is calculated according to the infrared intensity signal of reception；It will exhale again
The content C of the flow of air-breathing body and real-time carbon dioxide is exported to signal transmission unit；Signal transmission unit, using the time
The flow of area interleaved code packaging method forwarding breathing gas and in real time the content C of carbon dioxide to lung function instrument host or
Internet data center；Power supply unit, for providing working power for said units.
As shown in Fig. 2, the drive control in the present invention is connected with signal processing unit with ultrasonic flow transducer subelement
Controlling driving unit therein, alternately control ultrasonic sensor 1 and ultrasonic sensor 2 emit ultrasonic signal, ultrasonic sensing
Sonac 2 receives the transmitting signal of sonac 1, the transmitting excusing from death wave of sonac 2 during the transmitting excusing from death wave signal of device 1
Sonac 1 receives the transmitting signal of sonac 2 during signal, in driving unit control ultrasonic sensor transmitting ultrasound
Timing unit is opened while wave signal, the signal after signal condition unit improves is carried out thresholding inspection by level discriminator unit
Survey, when signal reaches preset value triggering timing unit stop timing, generate interrupt signal through interface unit be sent to drive control with
Center processing unit in signal processing unit carries out data processing.During propagation by measuring ultrasonic signal and adverse current
Between difference measure the flow velocity of breathing gas, so as to calculating outflow.
Ultrasonic signal propagation direction is consistent with airflow direction to transmit for fair current, as shown in Fig. 2 and Fig. 4 (a), ultrasonic sensing
Sonac 1 receives signal and is transmitted for fair current during the transmitting excusing from death wave signal of device 2.
Ultrasonic signal propagation direction is opposite with airflow direction for countercurrent, as shown in Fig. 2 and Fig. 4 (a), ultrasonic sensing
It is countercurrent that sonac 2, which receives signal, during the transmitting excusing from death wave signal of device 1.
The measuring method of flow includes the following steps：
Survey the velocity of sound and flow velocity of breathing gas：
If ultrasonic signal downbeam propagation time when breathing gas is propagated is Tf, the countercurrent direction propagation time is Tb,
The velocity of sound of breathing gas is Sr, flow velocity u, ultrasonic measurement distance LuFor definite value, ultrasonic sensor axis and conduit axis
Angle is θ, then：
The downbeam propagation time：Tf=Lucosθ/(Sr+u)
The countercurrent direction propagation time：Tb=Lucosθ/(Sr-u)
Carrying out simple operation can obtain：
The time and be that ultrasonic signal is propagated in breathing gas：Tf+Tb=2Lucosθ/(Sr-u)
Ultrasonic signal is in the time difference that breathing gas is propagated：Tb-Tf=2Lucosθ/(Sr-u)
The breathing gas flow velocity much smaller than the velocity of sound is neglected, (Sr-u) is approximately equal to breathing gas velocity of sound Sr
The time transmitted in breathing gas according to ultrasonic wave and formula can obtain the breathing gas velocity of sound
The time difference formula transmitted in breathing gas according to ultrasonic wave can obtain breathing gas flow velocity
Breathing gas flow Q can be obtained according to breathing gas flow velocity u and measurement pipeline sectional area A
Q=u × A
The capacity V of breathing gas can be obtained to breathing gas moment flow integration
V=∫ Qdt
Because acoustic velocity measutement value, which is proportional to, measures airway length Lu, measurement sensitivity also relationship proportional therewith.The present invention
Employ the measurement duct width more than usual same type of sensor, smaller θ angles are to improve equivalent measurement airway length Lu.It measures
Pipeline section is more than 60 millimeters for square type width.Simultaneously in order to reduce influence of the vortex for measurement accuracy, air inlet is using circle
It slips over the cross sectional shape crossed and is measured as possible using the relatively low low flow velocity region in big section.
As shown in figure 3, the drive control in the present invention is with signal processing unit, the infrared End-tidal carbon dioxide in senses
Device subelement is connected, control driving unit therein driven with impulse form in infrared transmitter, driving unit control in it is red
Synchronizing signal also is provided to lock phase amplifying unit while external transmitter emits signal, signal condition unit is by amplified signal
It is integrated and the signal after signal condition unit improves is carried out level detection by average treatment, level discriminator unit, determined
When generate the signal processing unit that interrupt signal is sent to through interface unit in drive control and signal processing unit and carry out at data
Reason.The intensity difference to be given off carbon dioxide by measuring infrared signal, to measure the specific peak absorbance rate of breathing gas, so as to
Calculate the spectrogram that the content that gives off carbon dioxide changes over time.
As shown in Fig. 4 (b), for the present invention the integrated ultrasonic flow rate that includes of system and in infrared End-tidal carbon dioxide
The practical schematic diagram of content level sensor probe portion mechanism.It is larger for ir-absorbance, the excessively weak situation of signal, may be used as
Structure shown in Fig. 4 (c) is to reduce absorption path-length.
As shown in figure 5, drive control and signal processing unit timesharing in the present invention, sending out staggeredly is ultrasonic infrared in
Driving control signal；Timesharing, reception and processing ultrasonic flow transducer the subelement infrared End-tidal carbon dioxide in staggeredly
The signal of sensor subunits；Treated each unit signal is with digital coding, and time zone load distribution mode is packaged, after encryption
Host computer or internet are transmitted to through signal transmission unit.For the numerical resolution realized the temporal resolution of this synchronization and measured
Rate, the signal refreshing frequency of ultrasonic flow transducer subelement infrared End-tidal carbon dioxide sensor subunits in need to exist
It is more than 1 kHz.Timer precision in ultrasonic flow transducer subelement is needed better than 50nS.
Environmental condition unit：According to infrared spectrum theory, different molecular has apparent absorption to the infrared light of its specific wavelength
Effect.According to Lambert-beer's law：
I=I0exp(-KCLR)
Wherein I0For infrared light by the light intensity after TCH test channel, I infrared lights enter the light intensity before TCH test channel, and K is gas
Absorption coefficient, C be under test gas concentration, LRLength for transmitted light path；Above formula points out, the length and gas of transmitted light path
When absorption coefficient determines, I/I can be passed through0Ratio calculates the concentration of tested gas.In practical application, due to infrared survey knot
Fruit affected by many factors can reduce precision such as temperature, air pressure, humidity etc..Environmental condition test cell contains temperature sensing
Device, pressure sensor, humidity sensor survey multidate information and can be used to the method for multi-point calibration to changes in environmental conditions shadow
It rings and carries out calculating compensation to restore test result precision.Compensation calculation method is known information.
As shown in fig. 6, signal transmission unit is responsible for driving, control is carried out with signal processing unit through local interface unit
Coding is packaged, host computer or internet node is transmitted to through wired or wireless interface unit after encryption.To ensure ultrasonic flow rate
Smallest synchronization time difference and information time is kept to differentiate in transmission process with the infrared data for exhaling last carbon dioxide real-time sampling
Rate, data on flows and gas concentration lwevel data are encoded using 16 bit formats, alternately timesharing, continuous one millisecond of decimal tool packet timing
Interval transmission, as shown in Figure 7.Receiving terminal carries out data interval time recovery again after receiving.Radio interface unit can be WIFI,
Bluetooth or other close range wireless communication means.
As shown in figure 8, power supply uses wired or wireless power supply mode.In the occasion for having AC power, this sensor can lead to
Cross the cable merged with connection power supply and the energy that can charge to battery unit offer under power control unit management and control such as USB
Amount, charhing unit carry out charge control and management.It when needing radio operation, is powered by interior with battery unit, power supply control is single
Member carries out electric discharge management.Power control unit also bears external power conditioning, system protection effect simultaneously.
Claims (10)
1. a kind of device of synchro measure breathing gas flow and ingredient, which is characterized in that including：
Ultrasonic flow transducer unit connects drive control and signal processing unit, for measuring downstream propagation times TfAnd adverse current
Propagation time Tb, and export to drive control and signal processing unit；
In infrared End-tidal carbon dioxide sensor unit, connect drive control and signal processing unit, exhaled for acquiring in real time
Last carbon dioxide infrared intensity signal is inhaled, and is exported to drive control and signal processing unit；
Environmental condition test cell connects drive control and signal processing unit, for measuring temperature, pressure, moisture signal, and
It exports to drive control and signal processing unit；
Drive control and signal processing unit, connection ultrasonic flow transducer subelement, in infrared End-tidal carbon dioxide sensing
Device subelement, environmental condition test cell, signal transmission unit, for driving and controlling said units work, receive above-mentioned list
The signal and data of member output；It is additionally operable to the downstream propagation times T receivedfWith adverse current propagation time TbCalculate breathing gas
Flow and the content C of real-time carbon dioxide is calculated according to the infrared intensity signal of reception；Again by the stream of breathing gas
The content C of amount and real-time carbon dioxide is exported to signal transmission unit；
Signal transmission unit connects drive control and signal processing unit, is exhaled using the forwarding of time zone interleaved code packaging method
The flow of air-breathing body and in real time the content C of carbon dioxide are to lung function instrument host or Internet data center；
Power supply unit connects said units, for providing working power for said units.
2. the device of a kind of synchro measure breathing gas flow according to claim 1 and ingredient, which is characterized in that described
Ultrasonic flow transducer subelement, including：
Tested gas measurement passageway, for guiding tested breathing gas；
Two sonacs, it is oblique be placed in measure gas channel both ends, between distance be Lu, and the axis of sonac
Axis angle with tested gas measurement passageway is θ, for emitting ultrasonic signal, receiving ultrasonic echo signal；Described two
A sonac alternate emission and received ultrasonic signal；
Power drive unit, connection drive control and signal processing unit, two sonacs, timing units；For driving
Dynamic control is under the control of signal processing unit, alternately controlling two sonac transmittings or receiving excusing from death wave signal, together
When the work of output pulse signal driving timing unit；
The preliminary conditioning unit of signal connects two sonacs；The ultrasonic signal of sonac output is filtered, it is whole
Shape and average treatment are then output to level discriminator unit；
Level discriminator unit, connection signal conditioning unit；Thresholding detection is carried out to the signal of signal condition unit output, works as signal
Triggering timing module stops timing when reaching predetermined threshold value；
Timing unit connects level discriminator unit；For recording ultrasonic pulse downstream propagation times TfWith adverse current propagation time Tb,
And it exports to interface unit；
Interface unit, connection drive control and signal processing unit, timing unit；For exporting downstream propagation times TfAnd adverse current
Propagation time TbTo drive control and signal processing unit.
3. the device of a kind of synchro measure breathing gas flow according to claim 1 and ingredient, which is characterized in that described
In infrared End-tidal carbon dioxide sensor subunits, including：
Middle infrared transmitter, trepanning is mounted on tested gas measurement passageway outer wall, and its launch window face is exposed to breathing
In gas；For emitting pulse modulated infrared radiation signal to tested gas；
Infrared detector, trepanning is mounted on tested gas measurement passageway outer wall, and it receives window side and is exposed to tidal air
In body, and it is staggered relatively with middle infrared transmitter；For acquiring the infrared intensity signal in tested gas in real time；
Power drive unit connects drive control and signal processing unit, middle infrared transmitter, lock phase amplification module；For
Under the control of drive control and signal processing unit, infrared transmitter works, while export synchronization in transmitting pulse signal driving
Signal is controlled to give lock phase amplifying unit；
Phase amplifying unit is locked, connects infrared detector；Processing is amplified for the infrared intensity signal to reception；
The preliminary conditioning unit of signal, connection lock phase amplifying unit；For carrying out integration peace to infrared intensity amplified signal
It handles, is then output to level discriminator unit；
Level discriminator unit, the preliminary conditioning unit of connection signal；For carrying out level detection to received signal, then timing is defeated
Go out REAL TIME INFRARED THERMAL IMAGE intensity signal to interface unit；
Interface unit connects drive control and signal processing unit；For REAL TIME INFRARED THERMAL IMAGE intensity signal to be forwarded to be controlled to driving
System and signal processing unit.
4. the device of a kind of synchro measure breathing gas flow according to claim 1 and ingredient, which is characterized in that described
Environmental condition test cell includes：Temperature sensor, pressure sensor, humidity sensor；Each sensor internal has
Driving and signal condition unit；For acquiring, improving temperature signal, pressure signal, moisture signal and be sent to drive control and letter
Control and digital signal center processing unit in number processing unit, the conditioning include amplification, filter, zero point stability.
5. the device of a kind of synchro measure breathing gas flow according to claim 1 and ingredient, which is characterized in that described
Drive control includes with signal processing unit：
Ultrasonic flow transducer driving unit, for be sonac provide pulse drive signal；
In infrared End-tidal carbon dioxide sensor driving unit, for middle infrared transmitter provide pulse drive signal；
Ultrasonic flow transducer interface unit, for forwarding downstream propagation times TfWith adverse current propagation time TbGive center processing list
Member；
In infrared End-tidal carbon dioxide sensor interface unit, the REAL TIME INFRARED THERMAL IMAGE intensity signal of reception simulate pre-
Processing, then export to center processing unit；The simulation pretreatment includes amplification, filtering, zero point stability, is used to implement modulus and turns
It changes；
Clock unit provides simultaneously operating signal to whole device；
Center processing unit, to carry number and the microprocessor of analog interface, for the downstream propagation times T to receptionfWith it is inverse
Flow propagation time TbIt calculates the flow of breathing gas and real-time dioxy is calculated according to the REAL TIME INFRARED THERMAL IMAGE intensity signal of reception
Change the content C of carbon；
Environmental condition test interface unit, for using multi-point calibration method to temperature signal, pressure signal, moisture signal into
Row, which calculates, to be compensated and exports to center processing unit；
Communication interface unit, connection signal transmission unit；For exporting the content C of the flow of breathing gas and real-time carbon dioxide
To signal transmission unit；
Power interface unit, for providing working power for said units.
6. the device of a kind of synchro measure breathing gas flow according to claim 1 and ingredient, which is characterized in that described
Signal transmission unit includes：
Wire signal transmission unit, be used to implement with the wired data transfer of lung function instrument host and ask for power supply supply；
Wireless signal transmitting unit is used to implement wireless data exchange and wireless control with lung function instrument host or internet.
7. the device of a kind of synchro measure breathing gas flow according to claim 1 and ingredient, which is characterized in that described
Power supply unit includes：
Power supplied locally unit is chargeable battery and its charging circuit；
External wired power supply unit, including dispatch from foreign news agency detecting, conditioning and protection circuit；For connecting external power supply；
Power Management Unit, for being managed to power supplied locally unit and external wired power supply unit.
8. a kind of method of synchro measure breathing gas flow and ingredient, which is characterized in that include the following steps：
Ultrasonic wave downstream propagation times T is measured by ultrasonic flow transducer unitfWith adverse current propagation time Tb, and export to drive
Dynamic control is used to calculate the flow of breathing gas with signal processing unit；
Infrared End-tidal carbon dioxide sensor subunits measure infrared intensity signal in, and export to drive control
It is used to calculate the content C of real-time carbon dioxide with signal processing unit.
9. the method for a kind of synchro measure breathing gas flow according to claim 8 and ingredient, which is characterized in that described
Drive control calculates the flow of breathing gas with signal processing unit, includes the following steps：
S1：Downstream propagation times T when ultrasonic signal is propagated in breathing gasf, adverse current propagation time TbSubstitute into formula
(1) breathing gas velocity of sound Sr is calculated：
S2：Time difference for being transmitted in breathing gas according to ultrasonic wave, the velocity of sound, breathing gas flow velocity u can be obtained according to formula (2)：
S3：According to breathing gas flow velocity u and pipeline sectional area A is measured, breathing gas flow Q can be obtained according to formula (3)：
Q=u × A (3)
Wherein, downstream propagation times TfFor ultrasonic signal propagation direction it is consistent with airflow direction when ultrasonic wave two excusing from death pass
The time propagated between sensor, adverse current propagation time TbFor ultrasonic signal propagation direction it is opposite with airflow direction when ultrasonic wave exist
The time propagated between two excusing from death sensors；Ultrasonic measurement distance is distance L between two sonacsuFor definite value,
Ultrasonic sensor axis is θ with tested gas measurement passageway axis angle.
10. the method for a kind of synchro measure breathing gas flow according to claim 8 and ingredient, which is characterized in that institute
It states drive control and the content C of the real-time carbon dioxide of signal processing unit calculating includes the following steps：
According to infrared spectrum theory and Lambert-beer's law：
I=I0exp(-KCLR) (4)
Wherein, I passes through the light intensity after TCH test channel, I for infrared light0Enter the light intensity before TCH test channel for infrared light, C is breathing
The content of carbon dioxide in gas, LRFor the length of transmitted light path, K is absorption coefficient, and K believes with temperature, pressure, humidity
Number correlation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710003931.0A CN108267183A (en) | 2017-01-04 | 2017-01-04 | A kind of device and method of synchro measure breathing gas flow and ingredient |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710003931.0A CN108267183A (en) | 2017-01-04 | 2017-01-04 | A kind of device and method of synchro measure breathing gas flow and ingredient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108267183A true CN108267183A (en) | 2018-07-10 |
Family
ID=62771588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710003931.0A Pending CN108267183A (en) | 2017-01-04 | 2017-01-04 | A kind of device and method of synchro measure breathing gas flow and ingredient |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108267183A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050284476A1 (en) * | 2004-06-24 | 2005-12-29 | Blanch Paul B | Method and apparatus for non-invasive prediction of intrinsic positive end-expiratory pressure (PEEPi) in patients receiving ventilator support |
| CN102770070A (en) * | 2009-12-28 | 2012-11-07 | 佛罗里达大学研究基金会有限公司 | System and method for assessing real time pulmonary mechanics |
| CN103705243A (en) * | 2013-12-16 | 2014-04-09 | 天津大学 | Method for synchronously monitoring concentration of carbon dioxide and breath flow amount in main flow mode |
| CN103948401A (en) * | 2014-05-20 | 2014-07-30 | 夏云 | Portable lung function instrument and lung function detection method |
| CN105105750A (en) * | 2015-09-15 | 2015-12-02 | 天津大学 | Main flow type human breathing flow and carbon dioxide concentration simultaneous monitoring device and method |
-
2017
- 2017-01-04 CN CN201710003931.0A patent/CN108267183A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050284476A1 (en) * | 2004-06-24 | 2005-12-29 | Blanch Paul B | Method and apparatus for non-invasive prediction of intrinsic positive end-expiratory pressure (PEEPi) in patients receiving ventilator support |
| CN102770070A (en) * | 2009-12-28 | 2012-11-07 | 佛罗里达大学研究基金会有限公司 | System and method for assessing real time pulmonary mechanics |
| CN103705243A (en) * | 2013-12-16 | 2014-04-09 | 天津大学 | Method for synchronously monitoring concentration of carbon dioxide and breath flow amount in main flow mode |
| CN103948401A (en) * | 2014-05-20 | 2014-07-30 | 夏云 | Portable lung function instrument and lung function detection method |
| CN105105750A (en) * | 2015-09-15 | 2015-12-02 | 天津大学 | Main flow type human breathing flow and carbon dioxide concentration simultaneous monitoring device and method |
Non-Patent Citations (2)
| Title |
|---|
| 俞俊棠 等: "《生物工艺学（下册）》", 31 May 1992, 华东化工学院出版社 * |
| 王仲生: "《智能检测与控制技术》", 30 September 2002, 西北工业大学出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5632281A (en) | Non-invasive estimation of arterial blood gases | |
| US5800361A (en) | Non-invasive estimation of arterial blood gases | |
| ITRM970314A1 (en) | PORTABLE SYSTEM FOR BREATH-BY-BREATH MEASUREMENT OF THE METABOLIC PARAMETERS OF A SUBJECT, WITH TRANSMISSION OF DATA IN TELEMETRY AND | |
| JP2019516442A (en) | Breath analysis device | |
| CN106061381B (en) | Detect the method for ARDS and the system for detecting ARDS | |
| CN103705244B (en) | Method for synchronously monitoring breath pressure and concentration of carbon dioxide in main flow mode | |
| CN208988880U (en) | A kind of cardiopulmonary exercise evaluating system | |
| US20160249828A1 (en) | On-airway pulmonary function tester | |
| Jaffe et al. | Continuous monitoring of respiratory flow and CO2 | |
| CN103487295B (en) | Expiration nitric oxide measures sampling apparatus | |
| CN111157480A (en) | Real-time dynamic quantitative detection device for carbon dioxide in human body exhaled air | |
| WO2023046169A1 (en) | Alveolar gas concentration measurement apparatus and method for separated airway | |
| Schlegelmilch et al. | Pulmonary function testing | |
| CN104391107B (en) | A kind of Exhaled nitric oxide measuring method not needing control expiratory gas flow | |
| CN210871585U (en) | Side-stream type carbon dioxide measuring device | |
| WO2018134823A1 (en) | Dual sensor | |
| CN205163962U (en) | Breathe protection equipment combined test stand | |
| CN105496412B (en) | A kind of expiration inflammation monitoring method and device | |
| CN108267480A (en) | One kind exhales hydrogen functions of intestines and stomach and disease detecting system and detection method | |
| WO2018041068A1 (en) | Flow sensor for pulmonary function testing, spirometer and testing method and application thereof | |
| CN108267183A (en) | A kind of device and method of synchro measure breathing gas flow and ingredient | |
| EP2303119B1 (en) | Ventilation analysis and monitoring | |
| CN212853458U (en) | Nasal tube type rapid comprehensive collector for CO2 and O2 concentration during sleeping | |
| CN205941349U (en) | Infrared gaseous disease detection auxiliary instrument | |
| CN108267182A (en) | The lung function instrument and method of a kind of synchro measure breathing gas flow and content |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180710 |
|
| RJ01 | Rejection of invention patent application after publication |