CN108229101B - 基于ngs的靶向测序数据模拟方法和装置 - Google Patents
基于ngs的靶向测序数据模拟方法和装置 Download PDFInfo
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CN109616154A (zh) * | 2018-12-27 | 2019-04-12 | 北京优迅医学检验实验室有限公司 | 测序深度的矫正方法及装置 |
CN109767813B (zh) * | 2018-12-27 | 2021-06-22 | 北京优迅医学检验实验室有限公司 | 测序深度的矫正方法及装置 |
CN109584959B (zh) * | 2018-12-27 | 2020-10-27 | 北京优迅医学检验实验室有限公司 | 测序深度的矫正方法及装置 |
CN109637585B (zh) * | 2018-12-27 | 2020-11-17 | 北京优迅医学检验实验室有限公司 | 测序深度的矫正方法及装置 |
CN109637586B (zh) * | 2018-12-27 | 2020-11-17 | 北京优迅医学检验实验室有限公司 | 测序深度的矫正方法及装置 |
CN111073952B (zh) * | 2018-12-29 | 2023-09-22 | 浙江安诺优达生物科技有限公司 | 构建dna文库的方法及其应用 |
CN116978453B (zh) * | 2023-09-22 | 2024-01-23 | 北京诺禾致源科技股份有限公司 | 判断融合基因真实性的方法和电子装置 |
Citations (3)
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CN104120181A (zh) * | 2011-06-29 | 2014-10-29 | 深圳华大基因医学有限公司 | 对染色体测序结果进行gc校正的方法及装置 |
CN105473741A (zh) * | 2013-06-21 | 2016-04-06 | 塞昆纳姆股份有限公司 | 用于遗传变异的非侵入性评估的方法和过程 |
CN107451419A (zh) * | 2017-07-14 | 2017-12-08 | 浙江大学 | 一种通过计算机程序模拟产生简化dna甲基化测序数据的方法 |
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104120181A (zh) * | 2011-06-29 | 2014-10-29 | 深圳华大基因医学有限公司 | 对染色体测序结果进行gc校正的方法及装置 |
CN105473741A (zh) * | 2013-06-21 | 2016-04-06 | 塞昆纳姆股份有限公司 | 用于遗传变异的非侵入性评估的方法和过程 |
CN107451419A (zh) * | 2017-07-14 | 2017-12-08 | 浙江大学 | 一种通过计算机程序模拟产生简化dna甲基化测序数据的方法 |
Non-Patent Citations (2)
Title |
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Identifying and mitigating bias in next-generation sequenci methods for chromatin biology;Clifford A. Meyer等;《Nature Reviews Genetics》;20140916;第15卷;全文 * |
Summarizing and correcting the GC content bias in high-throughput Sequencing;Yuval Benjamini等;《Nucleic Acids Research》;20120531;第40卷(第10期);全文 * |
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