CN108208332A - Promote growth of animal and improve Chinese medicine additive of immunity and preparation method thereof - Google Patents

Promote growth of animal and improve Chinese medicine additive of immunity and preparation method thereof Download PDF

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Publication number
CN108208332A
CN108208332A CN201611147673.5A CN201611147673A CN108208332A CN 108208332 A CN108208332 A CN 108208332A CN 201611147673 A CN201611147673 A CN 201611147673A CN 108208332 A CN108208332 A CN 108208332A
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animal
chinese medicine
medicine additive
preparation
raw material
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吴永丽
梁桂霞
宋楷
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Henan Hou Yi Industry Group Co Ltd
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Henan Hou Yi Industry Group Co Ltd
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Abstract

The present invention relates to the animal field of Chinese medicines, provide a kind of Chinese medicine additive for promoting growth of animal and improving animal immunizing power and preparation method thereof.Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 5 35, motherwort 5 35, Herba Epimedii 5 35, oriental wormwood 5 35, cordate houttuynia 5 35, Radix Paeoniae Alba 5 35, hawthorn 5 35, auxiliary material is dextrin, lactose, sucrose.The Chinese medicine additive of the present invention has the double action of pharmacological property and trophism concurrently, not only can directly improve the Immunoresistance of livestock and poultry, and can improve the appetite of livestock and poultry, improves Animal nutrition absorbability, effectively improves growth of animal and animal immunizing power.And have no toxic side effect, noresidue, have no drug resistance in animal body, edible animal meat quality is improved, increases the desire to buy of customer.Market acceptance of the present invention is high, and popularization difficulty is small, has good application and popularization value, can be effectively reduced animal feeding cost.

Description

Promote growth of animal and improve Chinese medicine additive of immunity and preparation method thereof
Technical field
The present invention relates to the animal field of Chinese medicines more particularly to promote growth of animal and the Chinese medicine additive of raising immunity And preparation method thereof.
Background technology
During animal-breeding, in order to improve the survival rate of animal, the speed of growth, some farms add in feed Western medicine or steroids chemical drugs are improved, however, environment is not only polluted in the application of Western medicine or steroids chemical drugs, can also be influenced The health of consumer is mutually refuted with the current consumption tide for pursuing ecology and pollution-free food.
Chinese herbal medicine is taken from nature and maintains its natural structure and the natural drug of bioactivity, and Chinese herbal medicine is to have Machine compound, has multiple nutritional components and bioactive substance, and effect not only has direct effect, but also have indirectly-acting more And the effects that integrally-regulated.Since Chinese medicine ingredient complexity is various, per a taste medicine inherently small compound, and in simply In the compound of medicine composition, that is, contain chemical composition, along with herbal mixture effect is different, constitute Chinese herb feed additive effect The diversity of function.
Chinese medicine Chinese medicine additive is that one kind has the effects that the drug substantially similar to antibiotic, chemical synthetic drug, and being should With the traditional Chinese veterinarian's theory in China and the physical property of Chinese herbal medicine, the cold and cool warm of negative and positive, the sour bitter sweet of object be pungent salty and object between relationship, Some are added in feed have and replenish qi to invigorate the spleen, digesting and appetizing, benefiting qi and nourishing blood, Yin-nourishing and body fluid promoting, the rightings such as tranquilizing and allaying excitement adjust negative and positive The Chinese medicine of balance.Chinese medicine not only has significantly as animal word feed additives in terms of resisting Animal diseases, promoting growth of animal Effect;And the exclusive characteristic of its mode of action, without hazard residue, being not likely to produce drug resistance etc., to have embodied huge application excellent Gesture.
Invention content
To solve the above problems, the present invention provides a kind of Chinese medicine additive for promoting growth of animal and improving animal immunizing power And preparation method thereof.
The technical scheme is that:Promote growth of animal and improve the Chinese medicine additive of immunity, including following weight The raw material of number:Radix Astragali 5-35, motherwort 5-35, Herba Epimedii 5-35, oriental wormwood 5-35, cordate houttuynia 5-35, Radix Paeoniae Alba 5-35, hawthorn 5-35, auxiliary material is dextrin, lactose, sucrose.
The parts by weight of the raw material are:Radix Astragali 10-20, motherwort 10-20, Herba Epimedii 10-20, oriental wormwood 10-20, fish raw meat Careless 10-20, Radix Paeoniae Alba 10-20, hawthorn 10-20;Auxiliary material is dextrin by weight ratio:Lactose:Sucrose=1:1:1.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of the 50%-80% of 10-20 times of volume is added in middle raw material, and it is 5~6.5 to adjust pH value, 20-40min, refluxing extraction 2-6 times are infiltrated, alcohol extract is collected in 40-80min, filtration every time;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, 60~80 DEG C of drying, granulation.
The preparation method of the Chinese medicine additive, step(2)For to step(1)10 times of volumes are added in middle raw material 60% ethyl alcohol, and adjust pH value as 5.6~5.8, infiltrate 30min, refluxing extraction 3 times, each 60min, alcohol is collected in filtration Extracting solution;
The preparation method of the Chinese medicine additive, step(3)In, the proportioning of the parts by weight of auxiliary material is dextrin:Lactose:Sugarcane Sugar=1:1:1.
Radix Astragali:Sweet, the tepor of property, returns spleen lung liver kidney channel;There is enhancing body's immunity, liver protection, diuresis, anti-aging, resist and answer Sharp, decompression and wide antibacterial action.
Motherwort:Property it is bitter, pungent, be slightly cold, Return liver, pericardium, bladder warp, disappear water promoting circulation of blood.Stasis eliminatings life is new, promoting blood circulation for regulating menstruation, diuresis Detumescence, it is clearing heat and detoxicating.
Herba Epimedii:Acrid-sweet flavor is warm-natured, walks liver kidney two warp.For mend the gate of vitality, strengthening the essence gas, strengthening the bones and muscles, tonifying kidney and strengthening yang key medicine.It is excessive The sheep leaves of pulse plants is containing ingredients such as icariine, volatile oil, ceryl alcohol, phytosterol, tannin, vitamin Es.It is also depressured, causes peripheral vessels Diastole, hypoglycemic, diuresis, kobadrin and the effect of vitamin E sample.Herba Epimedii can also increase cardiovascular and cerebrovascular blood flow, promote Hematopoiesis function, immune function and bone metabolism have anti-aging, antitumor and other effects.Xin Jiabo medical experts are the study found that excessive sheep The leaves of pulse plants can effectively kill breast cancer cell.
Oriental wormwood:Bitter, pungent, cold nature.Returns spleen, stomach, liver, gallbladder channel.There is the effect of eliminating dampness and heat, normalizing gallbladder to cure jaundice.Liver protection profit Courage, antipyretic, anti-inflammatory, reducing blood lipid, decompression, coronary dilatation effect.
Cordate houttuynia:Nature and flavor:《It does not record》:Acrid flavour, tepor;《Lv Cliff rocks book on Chinese herbal medicine》:It is cool in nature, it is nontoxic;《The southern regions of the Yunnan Province book on Chinese herbal medicine》:It is cold in nature, It is bitterly;《Detailed outline》:Pungent, tepor is slightly poisonous;《Medical center bun will》:It is sweet pungent salty.Channel tropism:《Bencao Jingshu》:Enter meridian of Hand-TAI YIN;《This Grass is new again》:Enter liver, lung two passes through.Cure mainly clearing heat and detoxicating, inducing diuresis to remove edema.Control pneumonia, lung abscess, hot dysentery, malaria, oedema, gonorrhoea, Leukorrhea, carbuncle swells, hemorrhoid, rectal prolapse, eczema, the favus of the scalp, mange.
Radix Paeoniae Alba:Bitter, acid, cold nature.Return liver, the spleen channel.Nourishing blood for regulating menstruation, astringing YIN to stop sweating, soft liver analgesic, suppressing liver-YANG.In vain Chinese herbaceous peony glycosides energy is anti-inflammatory, liver protection, drops enzyme, increases coronary flow, improves myocardial nutritional flow, expansion blood vessel, calmness, analgesia, resists Ulcer, the effect for adjusting blood glucose, while spleen lymphocyte proliferation can be promoted.
Hawthorn:Nature and flavor, sour, dry, food digesting stomach fortifying, scattered stasis change turbid lipid-loweringing.For meat stagnation, gastral cavilty turgor, rush down dysentery Abdominal pain, blood stasis closed, postpartum stasis, confidant sting, chest impediment and cardialgia, hernia pain, hyperlipidemia.Charred FRUCTUS CRATAEGI promoting digestion acts on Enhancing.For meat stagnation, rush down dysentery is not well.
The component pays attention to eighteen incompatibilities, nineteen counteraction in Chinese medicine according to the growth characteristic of animal, nutritional need, production law Conditionity compatibility, and pay attention to the concertedness in Chinese medicine between the nutriments such as vitamin, amino acid, mineral matter element with flying up and down Property, not only contribute to supplement diet in amino acid, vitamin and minerals deficiency, to balancing and improving livestock and poultry diet nutrition, Improve efficiency of feed utilization;The formula has invigorating spleen to remove dampness, enriching the blood and tonifying qi, clearing heat and detoxicating, warming kidney and enhancing yang, calm, adjusting machine of calming the nerves Yin-yang improves the pharmacological actions such as growth of animals or poultry performance, enhancing immunity of organisms, is finally reached saving and reduces livestock and poultry life Produce cost.
The present invention selects hawthorn to promote digestion, increases the appetite of animal, improves the nutrition intake amount of animal.Radix Astragali QI invigorating is helped Just, Radix Paeoniae Alba, oriental wormwood hepatic cholagogic, improvement cardiac muscle, promotion spleen lymphocyte proliferation, tune blood glucose, hypolipemic function, Herba Epimedii increase Cardiovascular and cerebrovascular blood flow promotes hematopoiesis function, bone metabolism, while promoting growth of animal, on the basis of the five internal organs are strong, and enhancing Animal autoimmune function;Play that motherwort is clearing heat and detoxicating simultaneously, the anti-inflammatory power of oriental wormwood and Radix Paeoniae Alba, confrontation ailment said due to cold or exposure, virus enter It invades, further improves immunocompetence.The present invention is whole from the traditional Chinese medical science under the guidance of theory of traditional Chinese medical science using traditional Chinese veterinary medicine theory as guidance Body idea is set out, with reference to the inherent characteristic of drug in itself, using the Radix Astragali with tonifying Qi and lifting yang effect as main ingredient, in conditioning the five internal organs Under purpose one group of Chinese medicine fodder addition that can promote growth of animal and improve animal immunizing power is constituted with reference to other medicines Agent.
Relative to the prior art, beneficial effects of the present invention are:
The Chinese medicine additive of the present invention has the double action of pharmacological property and trophism concurrently, not only can directly improve the immune of livestock and poultry and support Drag, and the appetite of livestock and poultry can be improved, it improves Animal nutrition absorbability, effectively improve growth of animal and animal immune Power.The present invention is allowed in the case where overall efficacy substantially enhances, cost by carrying out scientific and reasonable compatibility to plurality of Chinese It is greatly decreased instead, so that the addition cost in feed is being improved less than antibiotic and some chemical Chinese medicine additives The resistance of animal, the feed intake of animal and the absorption rate for feed nutrition, feed conversion rate etc. are better than antibiosis Plain and other chemical Chinese medicine additives, abandon injury of the chemicals to animal, have no toxic side effect in animal body, noresidue, nothing Drug resistance improves edible animal meat quality, increases the desire to buy of customer.Market acceptance of the present invention is high, and popularization difficulty is small, With good application and popularization value, animal feeding cost can be effectively reduced.
Specific embodiment
Embodiment 1
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 5-35, benefit Brittle Falsepimpernel Herb 5-35, Herba Epimedii 5-35, oriental wormwood 5-35, cordate houttuynia 5-35, Radix Paeoniae Alba 5-35, hawthorn 5-35, auxiliary material is dextrin, lactose, sugarcane Sugar.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 10-20 times of volume 50%-80% is added in middle raw material, and adjusts PH to 5-6.5, is infiltrated Alcohol extract is collected in 20-40min, refluxing extraction 2-6 times, every time 40-80min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material dextrin, lactose, sucrose, 60~80 DEG C of bakings It is dry, granulation.
Embodiment 2
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 10-20, benefit Brittle Falsepimpernel Herb 10-20, Herba Epimedii 10-20, oriental wormwood 10-20, cordate houttuynia 10-20, Radix Paeoniae Alba 10-20, hawthorn 10-20, auxiliary material is dextrin, breast Sugar, sucrose, weight proportion is dextrin:Lactose:Sucrose=1:1:1.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed by weight;
(2)To step(1)The ethyl alcohol of 10 times of volumes 60% is added in middle raw material, and adjusts PH to 5.6-5.8, infiltrates 30min, Alcohol extract is collected in refluxing extraction 3 times, each 60min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=1:1:1, 60~80 DEG C of drying, granulation.
Embodiment 3
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following weight:10 g of Radix Astragali, motherwort 10 G, 10 g of Herba Epimedii, 10 g of oriental wormwood, 10 g of cordate houttuynia, 10 g of Radix Paeoniae Alba, 10 g of hawthorn.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed by weight;
(2)To step(1)The ethyl alcohol of 10 times of volumes 50% is added in middle raw material, and adjusts PH to 5.0, infiltrates 30min, reflux Alcohol extract is collected in extraction 3 times, every time 60 min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=1:1:1, 60~80 DEG C of drying, granulation.
Embodiment 4
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following weight:20 g of Radix Astragali, motherwort 20 G, 10 g of Herba Epimedii, 10 g of oriental wormwood, 10 g of cordate houttuynia, 10 g of Radix Paeoniae Alba, 10 g of hawthorn.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed by weight;
(2)To step(1)The ethyl alcohol of 10 times of volumes 60% is added in middle raw material, and adjusts PH to 5.6-5.8, infiltrates 30min, Alcohol extract is collected in refluxing extraction 3 times, every time 60 min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=1:1:1, 60~80 DEG C of drying, granulation.
Embodiment 5
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 20, motherwort 20th, Herba Epimedii 15, oriental wormwood 10, cordate houttuynia 10, Radix Paeoniae Alba 10, hawthorn 10.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 15 times of volumes 50% is added in middle raw material, and adjusts PH to 5.8-6.2, infiltrates 40min, Alcohol extract is collected in refluxing extraction 5 times, every time 70 min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=2:1:2, 60~80 DEG C of drying, granulation.
Embodiment 6
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following weight:20 g of Radix Astragali, motherwort 15 G, 15 g of Herba Epimedii, 20 g of oriental wormwood, 10 g of cordate houttuynia, 10 g of Radix Paeoniae Alba, 10 g of hawthorn.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 20 times of volumes 80% is added in middle raw material, and adjusts PH to 6.2-6.5, infiltrates 50min, Alcohol extract is collected in refluxing extraction 2 times, every time 40 min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=1:3:2, 60~80 DEG C of drying, granulation.
Embodiment 7
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 20, motherwort 20th, Herba Epimedii 20, oriental wormwood 15, cordate houttuynia 15, Radix Paeoniae Alba 10, hawthorn 10.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 10 times of volumes 70% is added in middle raw material, and adjusts PH to 5-5.6,20min is infiltrated, returns Alcohol extract is collected in stream extraction 6 times, every time 80 min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=4:3,60 ~80 DEG C of drying, granulation.
Embodiment 8
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 5, motherwort 10th, Herba Epimedii 15, oriental wormwood 20, cordate houttuynia 25, Radix Paeoniae Alba 30, hawthorn 35.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 10 times of volumes 60% is added in middle raw material, and adjusts PH to 5-5.4,30min is infiltrated, returns Alcohol extract is collected in stream extraction 4 times, each 50min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=1:6:1, 60~80 DEG C of drying, granulation.
Embodiment 9
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 10, benefit are female Grass 15, Herba Epimedii 20, oriental wormwood 25, cordate houttuynia 30, Radix Paeoniae Alba 35, hawthorn 5.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 12 times of volume 50%-80% is added in middle raw material, and adjusts PH to 6.1-6.5, is infiltrated Alcohol extract is collected in 20min, refluxing extraction 5 times, each 50min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=2:5:4, 60~80 DEG C of drying, granulation.
Embodiment 10
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 15, benefit are female Grass 20, Herba Epimedii 25, oriental wormwood 30, cordate houttuynia 35, Radix Paeoniae Alba 5, hawthorn 10.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 14 times of volumes 50% is added in middle raw material, and adjusts PH to 5.6-5.8, infiltrates 30min, Alcohol extract is collected in refluxing extraction 4 times, each 40min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=10:1: 7,60~80 DEG C of drying, granulation.
Embodiment 11
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 20, benefit are female Grass 25, Herba Epimedii 30, oriental wormwood 35, cordate houttuynia 5, Radix Paeoniae Alba 10, hawthorn 15.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 16 times of volumes 60% is added in middle raw material, and adjusts PH to 5.8-6.0, infiltrates 40min, Alcohol extract is collected in refluxing extraction 2 times, each 70min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=1:10: 2,60~80 DEG C of drying, granulation.
Embodiment 12
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 25, benefit are female Grass 30, Herba Epimedii 35, oriental wormwood 5, cordate houttuynia 10, Radix Paeoniae Alba 15, hawthorn 20.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 18 times of volumes 50% is added in middle raw material, and adjusts PH to 6.0-6.2, infiltrates 25min, Alcohol extract is collected in refluxing extraction 3 times, each 80min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=4:6:5, 60~80 DEG C of drying, granulation.
Embodiment 13
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 30, benefit are female Grass 35, Herba Epimedii 5, oriental wormwood 10, cordate houttuynia 20, Radix Paeoniae Alba 25, hawthorn 30.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 20 times of volumes 50% is added in middle raw material, and adjusts PH to 6.2-6.5, infiltrates 35min, Alcohol extract is collected in refluxing extraction 4 times, each 60min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=8:9: 10,60~80 DEG C of drying, granulation.
Embodiment 14
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 35, benefit are female Grass 5, Herba Epimedii 10, oriental wormwood 15, cordate houttuynia 20, Radix Paeoniae Alba 25, hawthorn 30.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 10 times of volumes 80% is added in middle raw material, and adjusts PH to 5.6-5.8, infiltrates 20min, Alcohol extract is collected in refluxing extraction 4 times, each 70min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=5:7:6, 60~80 DEG C of drying, granulation.
Embodiment 15
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 15, benefit are female Grass 15, Herba Epimedii 5, oriental wormwood 5, cordate houttuynia 20, Radix Paeoniae Alba 20, hawthorn 15.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 10 times of volumes 60% is added in middle raw material, and adjusts PH to 5.6-5.8, infiltrates 30min, Alcohol extract is collected in refluxing extraction 3 times, each 60min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=1:1:1, 60~80 DEG C of drying, granulation.
Embodiment 16
Promote growth of animal and improve the Chinese medicine additive of immunity, include the raw material of following parts by weight:Radix Astragali 20, benefit are female Grass 20, Herba Epimedii 15, oriental wormwood 15, cordate houttuynia 5, Radix Paeoniae Alba 10, hawthorn 10.
The preparation method of the Chinese medicine additive, preparation process are:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of 10 times of volumes 60% is added in middle raw material, and adjusts PH to 5.6-5.8, infiltrates 30min, Alcohol extract is collected in refluxing extraction 3 times, each 60min, filtration;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, auxiliary material is dextrin:Lactose:Sucrose=1:1:1, 60~80 DEG C of drying, granulation.
Experiment contrast
Powder prepared by embodiment 1 is processed into oral liquid, granule or capsule, content specification:1 g finished products are equivalent to life 1.3 g of medicine.
Purposes:Improve the production performance and immunity of domestic animal, poultry.
Administration route:It is for oral administration(Mixed feeding, gavages mixed drink).
It is further proved of the invention below by way of experiment:
1st, influence of the Chinese medicine additive to sow feed intake during gestation and lactation
Basal diet is prepared according to trophic level, the healthy Suprapubic arch sling 30 that selection is pregnant 70-90 days, it is normal that sow presses pig farm Immune programme vaccine inoculation, period of gestation, sow feed 2 times, are fed daily during lactation 3 times, free water daily.Random point It it is 3 groups, i.e., negative control group is only fed:Basal diet, positive controls feeding:Basal diet+antibiotic, Chinese medicine preparation experiment Group feeding:Chinese medicine additive prepared by basal diet+embodiment 1.Sow during calculating sow gestation and during lactation is averaged Daily feed intake.
By result, it is found that the sow of gestation Chinese medicine preparation test group is averaged, daily feed intake is more than negative control group With positive controls;The sow of Chinese medicine preparation test group is averaged sum of the daily feed intake also greater than negative control group during lactation Positive controls.As a result such as table one:
2nd, the influence of Chinese medicine additive produced piglet weightening to sow
Litter weight and litter weight during weaned piglet, calculate and count piglet and put down during the birth of 3 groups of sow litters in experiment with computing 1 Equal daily gain.
By result it is found that the average daily gain of the produced piglet of Chinese medicine preparation test group sow is more than negative control group i.e. only The average daily gain of the produced piglet of sow of basal diet is added, is positive right also greater than antibiotic is added in basal diet According to the produced piglet average daily gain of sow of group.As a result such as table two:
3rd, the influence that Chinese medicine additive increases weight to growing and fattening pigs
Selective body focuses on the growing and fattening pigs 30 of 45-50 kg, is randomly divided into 3 groups, i.e., negative control group is only fed:Basal diet, sun Property control group fed:Basal diet+antibiotic, the feeding of Chinese medicine preparation test group:Chinese medicine prepared by basal diet+embodiment 1 adds Add agent, 3 groups of feeding 3 times daily, free water.The execution weight of 3 groups of growing and fattening pigs is weighed, is carried out according to corresponding feed mode It feeds, weighs the weight of 3 groups of growing and fattening pigs after 30 days, and calculate every daily gain of each group growing and fattening pigs.
By result it is found that after the feeding of 30 days, after adding Chinese medicine additive in basal diet, Chinese medicine preparation experiment The average daily gain of group is more than is not added with the additive group i.e. growing and fattening pigs of negative control group in basal diet, also greater than on basis The average daily gain of Antibiotic Additive group, that is, positive controls growing and fattening pigs is added in daily ration.As a result such as following table three:
4th, influence of the Chinese medicine preparation to piglet hog cholera antibody
30 piglets (not carrying out hog cholera immune) similar in selecting date of birth, are randomly divided into 3 groups, i.e., negative control group is only raised Hello:Basal diet, positive controls feeding:Basal diet+antibiotic, the feeding of Chinese medicine preparation test group:Basal diet+embodiment 1 Chinese medicine additive prepared, 3 groups of feeding 3 times daily, free water.With hog cholera antibody kit to the swine fever in piglet serum Antibody level is detected, and is illustrated according to kit, and blocking rate value >=40 are determined as the positive, blocking rate value≤40 are determined as It is negative.
Understand that the Chinese medicine preparation test group less adds additive negative control group by result, the swine fever in piglet body resists Body level increases.As a result such as following table four:
It can be seen from the experiment that taking the Chinese medicine additive of drug matching of the present invention, sow during gestation and lactation can be significantly improved Feed intake, and litter weight and litter weight during weaned piglet after lactation when improving the birth of piglet given birth to, can significantly improve The speed of weight increment of growing and fattening pigs;The resistance of pig can be significantly improved, although relatively horizontal using the hog cholera antibody in the pig body of antibiotic It is slightly lower, but Chinese medicine noresidue, viral drug resistance will not be increased.

Claims (5)

1. promote growth of animal and improve the Chinese medicine additive of immunity, it is characterised in that:Include the raw material of following parts by weight, Radix Astragali 5-35, motherwort 5-35, Herba Epimedii 5-35, oriental wormwood 5-35, cordate houttuynia 5-35, Radix Paeoniae Alba 5-35, hawthorn 5-35, auxiliary material are paste Essence, lactose, sucrose.
2. the Chinese medicine additive according to claim 1 for promoting growth of animal and improving immunity, it is characterised in that:It is described The parts by weight of raw material are:Radix Astragali 10-20, motherwort 10-20, Herba Epimedii 10-20, oriental wormwood 10-20, cordate houttuynia 10-20, Radix Paeoniae Alba 10-20, hawthorn 10-20;Auxiliary material is dextrin by weight ratio:Lactose:Sucrose=1:1:1.
3. the preparation method of the Chinese medicine additive according to claim 1 or 2 for promoting growth of animal and improving immunity, It is characterized in that:Its preparation process is:
(1)Raw material is weighed in parts by weight;
(2)To step(1)The ethyl alcohol of the 50%-80% of 10-20 times of volume is added in middle raw material, and it is 5~6.5 to adjust pH value, 20-40min, refluxing extraction 2-6 times are infiltrated, alcohol extract is collected in 40-80min, filtration every time;
(3)Alcohol extract rotary evaporation concentrates, and is concentrated into paste, adds in auxiliary material, 60~80 DEG C of drying, granulation.
4. the preparation method of the Chinese medicine additive according to claim 3 for promoting growth of animal and improving immunity, special Sign is:The preparation method of the Chinese medicine Chinese medicine additive, step(2)For to step(1)10 times of volumes are added in middle raw material 60% ethyl alcohol of amount, and it is 5.6~5.8 to adjust pH value, infiltrates 30min, refluxing extraction 3 times, each 60min filters, and collects Alcohol extract.
5. the preparation method of the Chinese medicine additive according to claim 3 for promoting growth of animal and improving immunity, special Sign is:The preparation method of the Chinese medicine Chinese medicine additive, step(3)In, the proportioning of the parts by weight of auxiliary material is dextrin: Lactose:Sucrose=1:1:1.
CN201611147673.5A 2016-12-13 2016-12-13 Promote growth of animal and improve Chinese medicine additive of immunity and preparation method thereof Pending CN108208332A (en)

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