CN108187216A - A kind of tumor locus drug delivery device - Google Patents

A kind of tumor locus drug delivery device Download PDF

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Publication number
CN108187216A
CN108187216A CN201711478212.0A CN201711478212A CN108187216A CN 108187216 A CN108187216 A CN 108187216A CN 201711478212 A CN201711478212 A CN 201711478212A CN 108187216 A CN108187216 A CN 108187216A
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China
Prior art keywords
drug delivery
outer barrel
tumor locus
cover body
upper cover
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CN201711478212.0A
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Chinese (zh)
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CN108187216B (en
Inventor
王兰华
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Geng Haitao
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention discloses a kind of tumor locus drug delivery devices, it includes outer barrel, round medicine storehouse, medicine feeding mechanism, limit cone cylinder, upper cover body and lower cover, upper cover body is rotatablely connected with cooperation at the top of outer barrel, the medicine feeding mechanism is included by the downward fixed fixing axle of upper cover body bottom center, the fixed first bevel gear in fixing axle lower end, the camshaft that outer barrel inner wall stretches out, fixed second bevel gear on the camshaft, rotation cam, drug delivery bar and resetting spring with annular chuck, the process that the present invention completes drug delivery by the medicine feeding mechanism being driven by bevel gear and cam mechanism and liquid recycles, and the effect liquid for passing through resetting spring recycles and drug delivery existence time is poor, to liquid and tumor locus enough action time.And pass through and limit cone cylinder and find positioning accurately in knub position, the process of drug delivery and liquid recycling can be completed only by rotary upper cover body, and operating process is very easy.In addition, the present invention also has the advantages that energy conservation and environmental protection, lower-cost.

Description

A kind of tumor locus drug delivery device
Technical field
The present invention relates to the field of medical instrument technology more particularly to a kind of tumor locus drug delivery devices.
Background technology
At present, when treating tumour, it is often necessary to operations, the mesh such as be observed the tumor locus of patient, sampled, be administered Means are mainly by taking or instillation related drugs carry out control treatment used by preceding, but this mode medication cycle It is longer, and because be by digest or the circulatory system carry out drug absorption and not directly against internal medicine tumour affected part carry out to Medicine often works slow, and control effect unobvious so as to need to treat for a long time, increase the burden of patient, to patient It makes troubles.Because very close between the therapeutic dose and toxic dose of chemotherapeutics, medical staff is past for dosage Toward the medication process for taking conservative and multiple courses for the treatment of, it is poor that chemotherapy effect is carried out by way of taking or instiling.At present, have Some drug delivery devices for being directly used in tumor locus are disclosed, the name announced such as State Intellectual Property Office on 03 15th, 2017 Referred to as " a kind of Internal Medicine-Oncology drug delivery device ", application publication number be CN106492335A patent of invention, announced to Medicine device uses dual-piston structure, is recycled in time after facilitating spray, can directly act on during use and be carried out with tumor locus Dispenser.However this device is inconvenient in use, staff needs hand steered a baffle, proficiency pull handle band Dynamic dual-piston structure, will also find dispenser position accurately and avoid dispenser position offset, it is easy to which bottom is applied during pull handle Medicine position is shaken, therefore fails to obtain preferable operating experience.
In view of the above-mentioned problems, it is necessary to provide one kind can administering position it is accurate and accurately control dosage, and simultaneous Has the tumour drug delivery device of necessary operation convenience.
Invention content
The purpose of the present invention is to provide a kind of tumor locus drug delivery device, by being driven by bevel gear and cam mechanism Medicine feeding mechanism complete drug delivery and liquid recycling process, and pass through resetting spring effect liquid recycling and drug delivery exist Time difference, to liquid and tumor locus enough action time.And pass through and limit cone cylinder and find positioning accurately in knub position, drug delivery and The process of liquid recycling can be completed only by rotary upper cover body, and operating process is very easy.
To achieve the above object, the present invention specifically adopts the following technical scheme that:
The present invention provides a kind of tumor locus drug delivery device, the drug delivery device includes outer barrel, round medicine storehouse, drug delivery Mechanism, limiting cone cylinder, upper cover body and lower cover, wherein, the outer barrel is the cylindrical structure that two-part is threadedly coupled, it is described on Cover is rotatablely connected with cooperation at the top of outer barrel, and the medicine feeding mechanism is included by the fixed fixation downwards of upper cover body bottom center Camshaft that axis, the fixed first bevel gear in fixing axle lower end, outer barrel inner wall stretch out, fixed second cone on the camshaft Gear, rotation cam, drug delivery bar and resetting spring with annular chuck, outer barrel is fixed in the camshaft front end by bearing Internal wall, the first bevel gear and second bevel gear engaged transmission, the rotation cam is fixed on tail end of camshaft, described to send Medicine bar is set under rotation cam and is driven by rotation cam, and the circle medicine storehouse includes the round administration storehouse at middle part and enclose to be set on Annular recovery bin outside the round administration storehouse, and the round administration storehouse passes through annular partition interval, institute with annular recovery bin It states and piston is equipped in round medicine storehouse, the piston bottom face corresponds to annular partition and is equipped with recessing groove, and the round medicine the top of the warehouse pair It answers and upward cylindrical bore is equipped at the center of piston, annular elastomeric spring abutment, the drug delivery are equipped on the inside of the cylindrical bore Bar stretches into cylindrical bore and is connected at the piston centre, and the resetting spring is sheathed on the outside of drug delivery bar, and resets bullet Spring bottom is fixed on the annular elastomeric spring abutment, is touched at the top of resetting spring with the annular chuck, the round administration orlop Portion is communicated with the delivery tube with downward check valve, and the annular recovery bin is uniformly provided with along bottom margin with unidirectional upwards The return hose of valve, the limiting cone cylinder are threadedly coupled the outer barrel bottom, and limited cone cylinder bottom is along its circumferencial direction Bottom chuck is uniformly provided with, the return hose is close to the limiting cone cylinder inner wall and extends to limiting cone cylinder bottom.
As the present invention to the preferred of said program, the outer barrel top is circumferentially with rotation slide unit, the upper cover body Equipped with the rotation sliding slot being adapted with the rotation slide unit, the outer barrel is with upper cover body by rotating slide unit with rotating sliding slot Cooperation rotation connection.The rotation of upper cover body provides rotation cam power in medicine feeding mechanism so that piston provides liquid.
As the present invention to the preferred of said program, the lower cover is connect with the limiting cone cylinder bottom thread.This hair Bright middle lower cover can be connect after the completion of device use with device, provide stable placement and protection.
As the present invention to the preferred of said program, the delivery tube is medical rigid woven hose.
As the present invention to the preferred of said program, the drug delivery bar is Z-type bar, and the upper end is set under rotation cam, end End is fixedly connected at piston centre.
As the present invention to the preferred of said program, the drug delivery bar upper end is equipped with ball.Ball can be into one in the present invention Step reduces the frictional resistance between drug delivery bar and rotation cam, improves the service life of drug delivery bar in device.
As the present invention to the preferred of said program, the return hose is close to limiting cone cylinder inner wall by stent and is fixed. Return hose is defined in the present invention and is conducive to liquid reflux, and only absorbs the liquid for spilling into device edge, it can Ensure that knub position obtains enough dosages, while the liquid of spilling is recycled, avoid damage to external skin.
As the present invention to the preferred of said program, the outer barrel inner wall is equipped with annular gasket, and the circle medicine storehouse leads to Annular gasket is crossed to be connected in outer barrel.Circle medicine storehouse of the invention is fixed on by way of clamping in outer barrel, can be facilitated Handled, sterilized after the administration is complete, in order to the addition again and use of liquid.
As the present invention to the preferred of said program, the outer barrel outside is equipped with handle.It should during easy to operation Device is fixed.
The beneficial effects of the present invention are:The present invention in use, will first by lower cover after limiting cone cylinder is removed It limits cone cylinder to fix at tumor locus by its bottom chuck, and attention is corresponding with knub position by delivery tube, determines that position is looked for Start administration process after standard, slowly upper cover body is rotated and causes rotation cam rotation that drug delivery bar is depressed into minimum point, at this time liquid Knub position is sent to by delivery tube under the driving of piston, is then rotated further upper cover body until resetting spring is complete by drug delivery bar All reset, at this time piston reach peak position, liquid passes through the return hose with check valve and is back to annular recovery bin, by The crossfire of liquid is avoided in the effect of check valve;The present invention has preferable fixed effect, in use singlehanded fixed dress Put outer barrel, another hand rotation upper cover body is easy to operate, is administered simultaneously that position is accurate, and dosage is accurate, can be with Corresponding rotation cam is portrayed in upper cover body and reaches minimum point and the mark of peak, to improve the precision of medication.In addition, this Invention also has the advantages that energy conservation and environmental protection, lower-cost.
Description of the drawings
Fig. 1 is a kind of structure diagram of tumor locus drug delivery device of the present invention.
Wherein, 1-outer barrel, 2-limiting cone cylinder, 3-upper cover body, 4-lower cover, 5-fixing axle, the 6-the first cone tooth Wheel, 7-camshaft, 8-second bevel gear, 9-rotation cam, 10-drug delivery bar, 11-annular chuck, 12-resetting spring, 13-circle administration storehouse, 14-annular recovery bin, 15-annular partition, 16-piston, 17-recessing groove, 18-cylindrical hole Road, 19-annular elastomeric spring abutment, 20-check valve, 21-delivery tube, 22-return hose, 23-bottom chuck, 24-rotation are slided Platform, 25-rotation sliding slot, 26-ball, 27-stent, 28-annular gasket, 29-handle.
Specific embodiment
In order to which the technical means, creative features, achievable purpose and effectiveness for realizing invention are easy to understand, with reference to Invention is expanded on further in specific embodiment.
A kind of tumor locus drug delivery device as shown in Figure 1, the drug delivery device include outer barrel 1, round medicine storehouse, drug delivery Mechanism, limiting cone cylinder 2, upper cover body 3 and lower cover 4, wherein, the cylindrical structure that the outer barrel 1 is threadedly coupled for two-part, institute It states upper cover body 3 to be rotatablely connected with 1 top cooperation of outer barrel, the medicine feeding mechanism includes solid downwards by 3 bottom center of upper cover body Camshaft 7, the camshaft 7 that fixed fixing axle 5, the fixed first bevel gear 6 in 5 lower end of fixing axle, 1 inner wall of outer barrel stretch out Upper fixed second bevel gear 8, rotation cam 9, the drug delivery bar 10 with annular chuck 11 and resetting spring 12, the camshaft 1 inner wall of outer barrel, the first bevel gear 6 and 8 engaged transmission of second bevel gear, the rotation are fixed in 7 front ends by bearing Cam 9 is fixed on 7 end of camshaft, and the drug delivery bar 10 is set on rotation cam 9 times and passes through rotation cam 9 and drives, the circle Shape medicine storehouse includes the round administration storehouse 13 at middle part and encloses the annular recovery bin 14 outside the round administration storehouse 13, and the circle Shape is administered storehouse 13 and is spaced with annular recovery bin 14 by annular partition 15, and piston 16, the piston are equipped in the circle medicine storehouse 16 bottom surfaces correspond to annular partition 15 equipped with recessing groove 17, and the round medicine the top of the warehouse is corresponded to and is equipped with upwards at the center of piston 16 Cylindrical bore 18,18 inside of the cylindrical bore is equipped with annular elastomeric spring abutment 19, and the drug delivery bar 10 stretches into cylindrical hole Road 18 is simultaneously connected at 16 center of piston, and the resetting spring 12 is sheathed on 10 outside of drug delivery bar, and 12 bottom of resetting spring Portion is fixed on the annular elastomeric spring abutment 19, and 12 top of resetting spring is touched with the annular chuck 11, the round administration storehouse 13 bottoms are communicated with the delivery tube 21 with downward check valve 20, and the annular recovery bin 14 is uniformly provided with band along bottom margin There is the return hose 22 of upward check valve 20, the limiting cone cylinder 2 is threadedly coupled 1 bottom of outer barrel, and limited cone cylinder 2 Bottom is uniformly provided with bottom chuck 23 along its circumferencial direction, and the return hose 22 is close to limiting 2 inner wall of cone cylinder and is extended to Limit 2 bottom of cone cylinder.
In this example, 1 top of outer barrel is circumferentially with rotation slide unit 24, and the upper cover body 3 is equipped with and described turn The adaptable rotation sliding slot 25 of dynamic slide unit 24, the outer barrel 1 is with upper cover body 3 by rotating slide unit 24 with rotating matching for sliding slot 25 Close rotation connection.The rotation of upper cover body 3 provides 9 power of rotation cam in medicine feeding mechanism so that piston 16 provides liquid.
In this example, the lower cover 4 is connect with limiting 2 bottom thread of cone cylinder.Lower cover 4 can in the present invention It after the completion of device use, is connect with device, stable placement and protection is provided.
In this example, the delivery tube 21 is medical rigid woven hose.
In this example, the drug delivery bar 10 is Z-type bar, and the upper end is set under rotation cam 9, and end is fixedly connected on work It fills at 16 centers.
In this example, 10 upper end of drug delivery bar is equipped with ball 26.Ball 26 can further reduce drug delivery in the present invention Frictional resistance between bar 10 and rotation cam 9 improves the service life of drug delivery bar 10 in device.
In this example, the return hose 22 by stent 27 be close to limit 2 inner wall of cone cylinder fix.To returning in the present invention Stream hose 22, which is defined, is conducive to liquid reflux, and only absorb the liquid for spilling into device edge, can ensure tumour position It puts to obtain enough dosages, while recycling the liquid of spilling into, avoids damage to external skin.
In this example, 1 inner wall of outer barrel is equipped with annular gasket 28, and the circle medicine storehouse is blocked by annular gasket 28 It is connected in outer barrel 1.Circle medicine storehouse of the invention is fixed on by way of clamping in outer barrel 1, can easily be tied in administration It handled, sterilized after beam, in order to the addition again and use of liquid.
In this example, 1 outside of outer barrel is equipped with handle 29.The device is fixed during easy to operation.
The beneficial effects of the present invention are:The present invention in use, first by lower cover 4 from limiting cone cylinder 2 remove after, Limiting cone cylinder 2 is fixed to by its bottom chuck 23 at tumor locus, and attention is corresponding with knub position by delivery tube 21, really Positioning put find accurately after start administration process, slowly upper cover body 3 is rotated so that rotation cam 9 rotate drug delivery bar 10 is depressed into it is minimum Point, at this time liquid knub position is sent to by delivery tube 21 under the driving of piston 16, be then rotated further upper cover body 3 until multiple Position spring 12 resets drug delivery bar 10 completely, and piston 16 reaches peak position at this time, and liquid passes through returning with check valve 20 Stream hose is back to annular recovery bin 14, since the effect of check valve 20 avoids the crossfire of liquid;The present invention has preferable solid Determine effect, in use singlehanded fixing device outer barrel handle 29, another hand rotation upper cover body 3 is easy to operate, It is accurate to be administered simultaneously position, dosage is accurate, can also be portrayed in upper cover body 3 corresponding rotation cam 9 reach minimum point and The mark of peak, to improve the precision of medication.In addition, the present invention also has the advantages that energy conservation and environmental protection, lower-cost.
The basic principle, main feature and advantage of invention has been shown and described above, the technical staff of the industry should Solution, invention is not restricted to the described embodiments, the above embodiments and description only describe the principle of invention, not Under the premise of being detached from spirit and range, invention also has various changes and modifications, these changes and improvements both fall within requirement In the invention scope of protection.The claimed range of invention is defined by appending claims and equivalents.

Claims (9)

1. a kind of tumor locus drug delivery device, which is characterized in that the drug delivery device includes outer barrel, round medicine storehouse, drug delivery machine Structure, limiting cone cylinder, upper cover body and lower cover, wherein, the cylindrical structure that the outer barrel is threadedly coupled for two-part, the upper cover Body is rotatablely connected with cooperation at the top of outer barrel, and the medicine feeding mechanism is included by the fixed fixation downwards of upper cover body bottom center Camshaft that axis, the fixed first bevel gear in fixing axle lower end, outer barrel inner wall stretch out, fixed second cone on the camshaft Gear, rotation cam, drug delivery bar and resetting spring with annular chuck, outer barrel is fixed in the camshaft front end by bearing Internal wall, the first bevel gear and second bevel gear engaged transmission, the rotation cam is fixed on tail end of camshaft, described to send Medicine bar is set under rotation cam and is driven by rotation cam, and the circle medicine storehouse includes the round administration storehouse at middle part and enclose to be set on Annular recovery bin outside the round administration storehouse, and the round administration storehouse passes through annular partition interval, institute with annular recovery bin It states and piston is equipped in round medicine storehouse, the piston bottom face corresponds to annular partition and is equipped with recessing groove, and the round medicine the top of the warehouse pair It answers and upward cylindrical bore is equipped at the center of piston, annular elastomeric spring abutment, the drug delivery are equipped on the inside of the cylindrical bore Bar stretches into cylindrical bore and is connected at the piston centre, and the resetting spring is sheathed on the outside of drug delivery bar, and resets bullet Spring bottom is fixed on the annular elastomeric spring abutment, is touched at the top of resetting spring with the annular chuck, the round administration orlop Portion is communicated with the delivery tube with downward check valve, and the annular recovery bin is uniformly provided with along bottom margin with unidirectional upwards The return hose of valve, the limiting cone cylinder are threadedly coupled the outer barrel bottom, and limited cone cylinder bottom is along its circumferencial direction Bottom chuck is uniformly provided with, the return hose is close to the limiting cone cylinder inner wall and extends to limiting cone cylinder bottom.
2. a kind of tumor locus drug delivery device according to claim 1, which is characterized in that circumferential at the top of the outer barrel to set There is rotation slide unit, the upper cover body is equipped with the rotation sliding slot being adapted with the rotation slide unit, and the outer barrel leads to upper cover body It crosses rotation slide unit and is rotatablely connected with rotating the cooperation of sliding slot.
3. a kind of tumor locus drug delivery device according to claim 1, which is characterized in that the lower cover and the limiting Cone cylinder bottom thread connects.
4. a kind of tumor locus drug delivery device according to claim 1, which is characterized in that the delivery tube is medical rigid Woven hose.
5. a kind of tumor locus drug delivery device according to claim 1, which is characterized in that the drug delivery bar is Z-type bar, Upper end is set under rotation cam, and end is fixedly connected at piston centre.
6. a kind of tumor locus drug delivery device according to claim 5, which is characterized in that the drug delivery bar upper end is equipped with rolling Pearl.
7. a kind of tumor locus drug delivery device according to claim 1, which is characterized in that the return hose passes through stent It is close to limiting cone cylinder inner wall to fix.
8. a kind of tumor locus drug delivery device according to claim 1, which is characterized in that the outer barrel inner wall is equipped with ring Shape gasket, the circle medicine storehouse are connected to by annular gasket in outer barrel.
9. a kind of tumor locus drug delivery device according to claim 1, which is characterized in that handle is equipped on the outside of the outer barrel Hand.
CN201711478212.0A 2017-12-29 2017-12-29 Tumor part drug delivery device Active CN108187216B (en)

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Application Number Priority Date Filing Date Title
CN201711478212.0A CN108187216B (en) 2017-12-29 2017-12-29 Tumor part drug delivery device

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Application Number Priority Date Filing Date Title
CN201711478212.0A CN108187216B (en) 2017-12-29 2017-12-29 Tumor part drug delivery device

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CN108187216A true CN108187216A (en) 2018-06-22
CN108187216B CN108187216B (en) 2021-03-16

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110680541A (en) * 2019-11-12 2020-01-14 张盈明 Auxiliary extension instrument for oral medicine
CN112843456A (en) * 2021-02-04 2021-05-28 王艳 Internal medicine is clinical with four limbs medicator

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Publication number Priority date Publication date Assignee Title
US5197484A (en) * 1990-09-18 1993-03-30 Peb Biopsy Corporation Method and device for precutaneous excisional breast biopsy
FR2756493A1 (en) * 1996-12-02 1998-06-05 Delab DEVICE FOR LOCAL ADMINISTRATION OF SOLID OR SEMI-SOLID FORMULATIONS
CN202104958U (en) * 2011-06-23 2012-01-11 李洪湘 Medical suction injection and endoscopic variceal ligation therapeutic apparatus
CN204073070U (en) * 2014-06-27 2015-01-07 张罗 Anti-return liquid medicine feeder
CN204468984U (en) * 2015-03-17 2015-07-15 张学勇 A kind of otorhinolaryngology administrator
CN205832370U (en) * 2016-04-05 2016-12-28 杨焕莲 A kind of Internal Medicine-Oncology doser
CN106492335A (en) * 2016-12-01 2017-03-15 闫朝光 A kind of Internal Medicine-Oncology doser
CN107261308A (en) * 2017-07-28 2017-10-20 梁晶 A kind of gynemetrics's clinic uses injecting type feeding device

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5197484A (en) * 1990-09-18 1993-03-30 Peb Biopsy Corporation Method and device for precutaneous excisional breast biopsy
FR2756493A1 (en) * 1996-12-02 1998-06-05 Delab DEVICE FOR LOCAL ADMINISTRATION OF SOLID OR SEMI-SOLID FORMULATIONS
CN202104958U (en) * 2011-06-23 2012-01-11 李洪湘 Medical suction injection and endoscopic variceal ligation therapeutic apparatus
CN204073070U (en) * 2014-06-27 2015-01-07 张罗 Anti-return liquid medicine feeder
CN204468984U (en) * 2015-03-17 2015-07-15 张学勇 A kind of otorhinolaryngology administrator
CN205832370U (en) * 2016-04-05 2016-12-28 杨焕莲 A kind of Internal Medicine-Oncology doser
CN106492335A (en) * 2016-12-01 2017-03-15 闫朝光 A kind of Internal Medicine-Oncology doser
CN107261308A (en) * 2017-07-28 2017-10-20 梁晶 A kind of gynemetrics's clinic uses injecting type feeding device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110680541A (en) * 2019-11-12 2020-01-14 张盈明 Auxiliary extension instrument for oral medicine
CN110680541B (en) * 2019-11-12 2021-07-20 张盈明 Auxiliary extension instrument for oral medicine
CN112843456A (en) * 2021-02-04 2021-05-28 王艳 Internal medicine is clinical with four limbs medicator

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Inventor after: Geng Haitao

Inventor after: Zhang Xiaoxia

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Inventor after: Wang Lanhua

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