CN108179073B - Mild bactericidal laundry detergent and preparation method thereof - Google Patents
Mild bactericidal laundry detergent and preparation method thereof Download PDFInfo
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- CN108179073B CN108179073B CN201810030166.6A CN201810030166A CN108179073B CN 108179073 B CN108179073 B CN 108179073B CN 201810030166 A CN201810030166 A CN 201810030166A CN 108179073 B CN108179073 B CN 108179073B
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- 239000003599 detergent Substances 0.000 title claims abstract description 44
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 230000000844 anti-bacterial effect Effects 0.000 title claims description 15
- 229930182470 glycoside Natural products 0.000 claims abstract description 46
- -1 alkyl glycoside Chemical class 0.000 claims abstract description 44
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 24
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims abstract description 22
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 claims abstract description 20
- 229930101531 artemisinin Natural products 0.000 claims abstract description 20
- 229960004191 artemisinin Drugs 0.000 claims abstract description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 20
- 239000008367 deionised water Substances 0.000 claims abstract description 19
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 19
- 150000002338 glycosides Chemical class 0.000 claims abstract description 19
- 230000001954 sterilising effect Effects 0.000 claims abstract description 19
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 19
- 239000002562 thickening agent Substances 0.000 claims abstract description 12
- 239000012752 auxiliary agent Substances 0.000 claims abstract description 9
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 72
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 58
- 238000003756 stirring Methods 0.000 claims description 35
- 238000006243 chemical reaction Methods 0.000 claims description 26
- 230000001804 emulsifying effect Effects 0.000 claims description 26
- 239000003054 catalyst Substances 0.000 claims description 19
- 239000000243 solution Substances 0.000 claims description 19
- 239000002131 composite material Substances 0.000 claims description 18
- 239000011259 mixed solution Substances 0.000 claims description 14
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 12
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 11
- 229960001484 edetic acid Drugs 0.000 claims description 11
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 9
- 239000007864 aqueous solution Substances 0.000 claims description 8
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical group CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 239000000661 sodium alginate Substances 0.000 claims description 6
- 235000010413 sodium alginate Nutrition 0.000 claims description 6
- 229940005550 sodium alginate Drugs 0.000 claims description 6
- 239000000686 essence Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 4
- 235000010987 pectin Nutrition 0.000 claims description 3
- 239000001814 pectin Substances 0.000 claims description 3
- 229920001277 pectin Polymers 0.000 claims description 3
- 229960000292 pectin Drugs 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 239000000230 xanthan gum Substances 0.000 claims description 3
- 235000010493 xanthan gum Nutrition 0.000 claims description 3
- 229920001285 xanthan gum Polymers 0.000 claims description 3
- 229940082509 xanthan gum Drugs 0.000 claims description 3
- 230000001133 acceleration Effects 0.000 claims description 2
- 239000006081 fluorescent whitening agent Substances 0.000 claims description 2
- 239000000049 pigment Substances 0.000 claims description 2
- 230000001502 supplementing effect Effects 0.000 claims description 2
- 238000005406 washing Methods 0.000 abstract description 7
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 description 12
- 229930182478 glucoside Natural products 0.000 description 8
- 239000004094 surface-active agent Substances 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 235000000177 Indigofera tinctoria Nutrition 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 238000004945 emulsification Methods 0.000 description 3
- 150000008131 glucosides Chemical class 0.000 description 3
- 229940097275 indigo Drugs 0.000 description 3
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000002244 precipitate Substances 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 238000006555 catalytic reaction Methods 0.000 description 2
- 239000003093 cationic surfactant Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
- 241000049464 Artemisia apiacea Species 0.000 description 1
- 235000011570 Artemisia caruifolia var apiacea Nutrition 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000013522 chelant Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 125000003147 glycosyl group Chemical group 0.000 description 1
- 239000008233 hard water Substances 0.000 description 1
- 150000007529 inorganic bases Chemical class 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/835—Mixtures of non-ionic with cationic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/22—Carbohydrates or derivatives thereof
- C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/382—Vegetable products, e.g. soya meal, wood flour, sawdust
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/38—Cationic compounds
- C11D1/62—Quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/662—Carbohydrates or derivatives
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/667—Neutral esters, e.g. sorbitan esters
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Detergent Compositions (AREA)
Abstract
The invention provides a mild sterilization laundry detergent which comprises the following components in parts by mass based on 100 parts by mass: 1.0-3.0 parts of alkyl glycoside citrate, 3.0-10.0 parts of alkyl glycoside, 1.5-2.5 parts of glycosyl amide quaternary ammonium salt, 1.5-3.0 parts of artemisinin extracting solution, 0.1-1 part of thickening agent, 0.1-5 parts of other auxiliary agents and the balance of deionized water. The laundry detergent has the advantages of mild sterilization, no residue and easy degradation, is suitable for washing infant clothes and close-fitting clothes, and has wide application prospect. Meanwhile, the invention also provides a preparation method of the mild sterilization laundry detergent.
Description
Technical Field
The invention belongs to the field of washing products, and particularly relates to a mild bactericidal laundry detergent and a preparation method thereof.
Background
Compared with washing powder, the laundry detergent has the advantages of easy dissolution, high active matter content, convenient use and the like, and is very popular with people. However, most of the conventional laundry detergent formulations use sulfate, alcohol ether carboxylate or sulfonate surfactants as active substances, alkanolamide 6501 as a thickening agent, alcohol ether and alcohol ether glycoside substances as main components, dioxane easily remains, and C is8-16The quaternary ammonium salt cationic surfactant is used as a bactericide, so that the laundry detergent has strong irritation, harmful substances are easy to remain on washed articles, the laundry detergent is used for washing clothes, especially infant clothes and underwear, the body health of people can be affected, and meanwhile, the formula contains a part of difficultly-degradable components and can pollute the environment. Therefore, the development of a laundry detergent which has biocompatibility, has a killing effect on pathogenic microorganisms, has no harmful substance residue, and is mild and moist to skin can meet new requirements of people on clothes health and environmental protection.
The glucoside citrate surfactant has good stability, can chelate metal ions to improve the hard water resistance of a formula, has excellent low-temperature solubility and easy rinsing performance, can be compounded with various surfactants and assistants, cannot form an insoluble organic complex particularly when being compounded with a cationic surfactant or other cationic assistants, and is a green multifunctional surfactant. Although alkyl glycoside citrate belongs to alkyl glycoside citrate surfactants, the main production raw materials of fatty alcohol, glucose, citric acid and the like are biomass-based renewable raw materials derived from natural products, are safe, non-toxic and easy to degrade, the product is not localized at present due to the limitation of the production technology of the alkyl glycoside citrate, and the application cost is greatly improved mainly by depending on the over-high price of the imported product. Therefore, the method for synthesizing the alkyl glycoside citrate which is low in cost and easy to dissolve in the laundry detergent is developed, and has important practical significance for developing the bactericidal laundry detergent with mild research performance.
Disclosure of Invention
In view of the above, the invention provides a mild bactericidal laundry detergent and a preparation method thereof, so as to solve the above problems.
Specifically, the invention adopts the following technical scheme:
the mild sterilization laundry detergent comprises the following components in parts by mass based on 100 parts by mass: 1.0-3.0 parts of alkyl glycoside citrate, 3.0-10.0 parts of alkyl glycoside, 1.5-2.5 parts of glycosyl amide quaternary ammonium salt, 1.5-3.0 parts of artemisinin extracting solution, 0.1-1 part of thickening agent, 0.1-5 parts of other auxiliary agents and the balance of deionized water.
Preferably, the alkyl glycoside citrate is a compound having the general formula:
wherein R is an alkyl group having a carbon chain length of 8 to 14 carbons, and n is 1.2 to 1.6.
Preferably, the quaternary ammonium glycosylamide salt is a compound having the general formula:
wherein R is1Is glucosyl or lactose group; r2Is an alkyl group having a carbon chain length of 10 to 16 carbons.
Based on the above, it comprises the following components in parts by mass, calculated as 100 parts by mass: 1.8-2.5 parts of alkyl glycoside citrate, 7.0-7.5 parts of alkyl glycoside, 1.5-2.5 parts of glycosyl amide quaternary ammonium salt, 2.0-2.5 parts of artemisinin extracting solution, 0.5-4 parts of thickening agent, 0.5-0.7 part of other auxiliary agents and the balance of deionized water.
Based on the above, the artemisinin extracting solution is obtained by steaming, extracting and concentrating dry artemisia apiacea leaves by deionized water, and the concentration of artemisinin in the artemisinin extracting solution is 1.5-2.5 g/ml.
Based on the above, the thickener is sodium alginate, xanthan gum or pectin.
Based on the above, the other auxiliary agents are one or a mixture of at least two of essence, fluorescent whitening agent, sodium hydroxide, potassium hydroxide and pigment.
Based on the above, the pH value of the mild sterilization laundry detergent is 7.0-7.5.
The preparation method of the mild bactericidal laundry detergent comprises the following steps: firstly, reacting citric acid and alkyl glucoside in a reaction kettle with a stirring head and an emulsifying head in the kettle under the vacuum condition under the catalysis of a hydrogen peroxide composite catalyst to obtain a mixed solution of alkyl glucoside citrate and alkyl glucoside; adding glycosyl amide quaternary ammonium salt, artemisinin extracting solution, thickening agent, other auxiliary agents and deionized water into the mixed solution, and uniformly mixing to obtain a laundry detergent product; the hydrogen peroxide composite catalyst comprises ethylene diamine tetraacetic acid and hydrogen peroxide, and the mass ratio of the ethylene diamine tetraacetic acid to the hydrogen peroxide is (96-99): (1-4).
Based on the above, the step of obtaining the mixed solution comprises: firstly adjusting the rotating speed of the stirring head to be 20-60 r/min, adjusting the rotating speed of the emulsifying head to be 30-800 r/min, adding 27-38% of alkyl glycoside aqueous solution by mass fraction into the reaction kettle, then gradually adding citric acid, increasing the rotating speed of the emulsifying head according to the acceleration of 100-200 r/min increase per minute in the process of adding the citric acid, after finishing adding the citric acid for 20-50 min, adjusting the rotating speed of the stirring head to be 80-120 r/min, adjusting the rotating speed of the emulsifying head to be 13000-15000 r/min, adding the hydrogen peroxide composite catalyst, and reacting for 30-60 min under the conditions of vacuum degree of 4000-8000 Pa and temperature of 36-48 ℃ to obtain the mixed solution.
Based on the above, the steps of obtaining the laundry detergent product comprise: firstly adjusting the rotating speed of the emulsifying head to 800-1000 r/min, adjusting the rotating speed of the stirring head to 30-60 r/min, adding the glycosyl amide quaternary ammonium salt and the artemisinin extracting solution and supplementing deionized water to 90% of the formula amount, then adding the thickening agent and stirring for 30-60 min to mix uniformly, then adjusting the pH value to 7.0-7.5, removing the vacuum in the reaction kettle and adjusting the vacuum to normal pressure, then adding the other auxiliary agents and the rest deionized water, adjusting the rotating speed of the emulsifying head to 300-500 r/min, adjusting the rotating speed of the stirring head to 20-50 r/min, and continuing stirring for 30-50 min to obtain the laundry detergent product.
Based on the above, in the step of obtaining the mixed solution, the mass ratio of the hydrogen peroxide composite catalyst to the alkyl glycoside added is (1.5-10): 100.
compared with the prior art, the invention has outstanding substantive characteristics and remarkable progress. Specifically, the mild sterilization laundry detergent provided by the invention takes alkyl glucoside citrate and alkyl glucoside as main active ingredients, and the compounding of the alkyl glucoside citrate and the alkyl glucoside is warmer for human skin, has a good effect of moistening skin, is more suitable for hand washing, and is not only suitable for washing infants and underwear; meanwhile, the glycosyl amide quaternary ammonium salt which has the glycosyl and the quaternary ammonium salt with high surface activity and high efficiency and strong bactericidal property is compounded with the artemisinin extracting solution to be used as the bactericide, so that the bactericidal effect can be ensured, and the generation of drug resistance can be avoided; furthermore, the thickening agent of the mild bactericidal laundry detergent is low in irritation due to the adoption of natural thickening agents such as sodium alginate, xanthan gum or pectin, no harmful substances are generated in the production or use process, and the mild bactericidal laundry detergent is more environment-friendly; furthermore, the mild sterilization laundry detergent is neutral, is milder, and is suitable for washing infant clothes and close-fitting clothes.
Meanwhile, the preparation method of the mild sterilization laundry detergent provided by the invention is simple, easy to operate and suitable for large-scale production; meanwhile, the method also comprises a step of preparing alkyl glycoside citrate, wherein the alkyl glycoside citrate is prepared by reacting alkyl glycoside and citric acid under the catalysis of a hydrogen peroxide composite catalyst, and the alkyl glycoside is excessive, so that a product after the reaction is mainly a mixed solution of the alkyl glycoside citrate and the alkyl glycoside, can be directly used, and the cost of the mild sterilization laundry detergent is effectively reduced; meanwhile, ethylene diamine tetraacetic acid in the hydrogen peroxide composite catalyst can play a role of a stabilizer, so that hydrogen peroxide is prevented from losing catalytic action by being reduced in the reaction process of alkyl glycoside and citric acid, inorganic base is added after the reaction of alkyl glycoside and citric acid is finished to adjust the pH value to be alkalescence, the ethylene diamine tetraacetic acid is neutralized and cannot play a role of the stabilizer any more, the hydrogen peroxide is reduced to water, no residue is generated, and irritation to infant clothes is avoided.
Detailed Description
The technical solution of the present invention is further described in detail by the following embodiments.
Example 1
The mild bactericidal laundry detergent comprises the following components in percentage by weight:
wherein, 1ml of the artemisinin extract contains 1.5g of artemisinin.
The mild sterilization laundry detergent is prepared in a reaction kettle with a stirring head and an emulsifying head inside, and the preparation method comprises the following steps:
preparation of alkyl glycoside citrate C8-10Mixing alkyl glycoside and partial deionized water to obtain C with mass fraction of 30%8-10An aqueous solution of an alkylglycoside, adding said C8-10Adding an alkyl glycoside aqueous solution into the reaction kettle, adjusting the rotating speed of the stirring head to be 50r/min, adjusting the rotating speed of the emulsifying head to be 600r/min, stirring for 15min, gradually adding citric acid, simultaneously increasing the rotating speed of the emulsifier to be 200r/min per minute, controlling the adding time of the citric acid to be 30min, adjusting the rotating speed of the emulsifying head to be 13000r/min after the addition of the citric acid is finished, adjusting the rotating speed of the stirring head to be 80r/min, adding a hydrogen peroxide composite catalyst, reacting for 40min under the conditions that the vacuum degree is 5000Pa and the reaction temperature is 42 ℃ to obtain a mixed solution of alkyl glycoside citrate and alkyl glycoside, sampling and detecting the content of the citric acid in the mixed solution to be 0.05%, and the hydrogen peroxide composite catalyst and the C are mixed catalyst8-10The mass ratio of the alkyl glycoside is 1: 10; the mass ratio of ethylene diamine tetraacetic acid to hydrogen peroxide in the hydrogen peroxide composite catalyst is 96: 4;
adjusting the rotating speed of the emulsifying head to 800r/min, the rotating speed of the stirring head to 50r/min, and keeping the vacuum degree to 5000Pa in the product preparation, and adding C into the reaction kettle14Adding 90% deionized water into glycosyl amide quaternary ammonium salt and artemisinin extracting solution, adding sodium alginate, and stirring for 50 min; and dropwise adding sodium hydroxide into the reaction kettle, adjusting the pH value of the solution to be 7.0, removing the vacuum, adjusting the solution to be normal pressure, adding essence, indigo and the rest deionized water into the reaction kettle, adjusting the rotating speed of the emulsifying head to be 500r/min, adjusting the rotating speed of the stirring head to be 30r/min, and continuously stirring for 30min until the solution is uniform and transparent to obtain the mild sterilization laundry detergent product.
Example 2
The mild bactericidal laundry detergent comprises the following components in percentage by weight:
wherein, each 1ml of the artemisinin extract contains 2.5g of artemisinin.
The mild sterilization laundry detergent is prepared in a reaction kettle with a stirring head and an emulsifying head inside, and the preparation method comprises the following steps:
preparation of alkyl glycoside citrate C10-12Mixing alkyl glycoside and partial deionized water to obtain C with mass fraction of 27%10-12An aqueous solution of an alkylglycoside, adding said C10-12Adding an alkyl glycoside aqueous solution into the reaction kettle, adjusting the rotating speed of the stirring head to be 60r/min, adjusting the rotating speed of the emulsifying head to be 800r/min, stirring for 20min, gradually adding citric acid, simultaneously increasing the rotating speed of the emulsifying head by 150r/min per minute, controlling the adding time of the citric acid to be 50min, adjusting the rotating speed of the emulsifying head to be 14000r/min after the citric acid is added, adjusting the rotating speed of the stirring head to be 80r/min, adding a hydrogen peroxide composite catalyst, reacting for 45min under the conditions that the vacuum degree is 4500Pa and the reaction temperature is 45 ℃ to obtain a mixed solution of alkyl glycoside citrate and alkyl glycoside, sampling and detecting the content of the citric acid in the mixed solution to be 0.07%, and adjusting the rotating speed of the hydrogen peroxide composite catalyst and the C to be 60r/min10-12The mass ratio of the alkyl glycoside is 7.2: 100; the hydrogen peroxide composite catalyst consists of ethylene diamine tetraacetic acid and hydrogen peroxide, and the mass ratio of the ethylene diamine tetraacetic acid to the hydrogen peroxide is 97: 3;
adjusting the rotating speed of the emulsifying head to 600r/min, the rotating speed of the stirring head to 60r/min, maintaining the vacuum degree to 4500Pa, and adding C into the reaction kettle16Adding 90% deionized water into glycosyl amide quaternary ammonium salt and artemisinin extracting solution, adding sodium alginate, and continuously stirring for 50 min; and dropwise adding sodium hydroxide into the reaction kettle, adjusting the pH value to 7.2, removing the vacuum, adjusting the pressure to normal pressure, continuously adding essence, indigo violet and the rest deionized water into the reaction kettle, adjusting the rotating speed of the emulsifying head to 600r/min, continuously stirring the mixture for 30min until the solution is uniform and transparent, and thus obtaining the mild sterilization laundry detergent product.
Example 3
The laundry detergent comprises the following components in percentage by weight:
wherein, each 1ml of the artemisinin extract contains 2.0g of artemisinin.
The mild sterilization laundry detergent is prepared in a reaction kettle with a stirring head and an emulsifying head inside, and the preparation method comprises the following steps:
preparation of alkyl glycoside citrate C12-14Mixing alkyl glycoside and partial deionized water to obtain 38% C8-10An aqueous solution of an alkylglycoside, adding said C12-14Adding alkyl glycoside aqueous solution into in the reation kettle, adjusting the rotational speed of agitator head is 20r/min, the rotational speed of emulsification head 700r/min, stirring 40min, add citric acid gradually, increase every minute simultaneously at the in-process of adding citric acid emulsification head rotational speed 180r/min, the control of the time of addition of citric acid is at 60min, adjust after citric acid adds, the rotational speed of emulsification head 15000r/min, the rotational speed of agitator head is 100r/min, adds hydrogen peroxide composite catalyst, under the condition that vacuum is 4200Pa, reaction temperature is 42 ℃, reaction 60min obtains the mixed solution of alkyl glycoside citrate and alkyl glycoside, the sample detection citric acid content in the mixed solution is 0.05%, hydrogen peroxide composite catalyst with C12-14The mass ratio of the alkyl glycoside is 1.5: 100; the hydrogen peroxide composite catalyst consists of ethylene diamine tetraacetic acid and hydrogen peroxide, and the mass ratio of the ethylene diamine tetraacetic acid to the hydrogen peroxide is 99: 1;
adjusting the rotation speed of the emulsifying head to be 500r/min, the rotation speed of the stirring head to be 60r/min, keeping the vacuum degree to be 4200Pa, and adding C into the reaction kettle12Adding 90% deionized water into glycosyl amide quaternary ammonium salt and artemisinin extracting solution, adding sodium alginate, and continuously stirring for 50 min; and (3) dropwise adding potassium hydroxide into the reaction kettle, adjusting the pH value to 7.5, removing the vacuum, adjusting the pressure to normal pressure, continuously adding essence, indigo and the rest deionized water, adjusting the rotating speed of the emulsifying head to 500r/min, adjusting the rotating speed of the stirring head to 50r/min, and continuously stirring for 50min until the solution is uniform and transparent, thereby obtaining the mild sterilization laundry detergent product.
Performance testing
The mild sterilization laundry detergent obtained in the examples 1 to 3 has no peculiar smell, and no suspended matters or precipitates. The detection proves that the stability of the laundry detergent is good, the laundry detergent is placed in a refrigerator at the temperature of (5 +/-2) ℃ for 24 hours, and the laundry detergent is observed when taken out and restored to the room temperature, is not layered, has no precipitate, and is transparent and not turbid; placing in a heat preservation box at the temperature of (40 +/-2) ℃ for 24h, taking out and observing, wherein the product is not layered, has no precipitate, and is transparent and not turbid.
Through detection, all indexes of the mild sterilization laundry detergent provided by the invention meet the standard requirements of GB/T1224-2007 liquid detergent for clothing.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention and not to limit it; although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art will understand that: modifications to the specific embodiments of the invention or equivalent substitutions for parts of the technical features may be made; without departing from the spirit of the present invention, it is intended to cover all aspects of the invention as defined by the appended claims.
Claims (1)
1. A preparation method of a mild bactericidal laundry detergent comprises the following steps:
in a reaction kettle internally provided with a stirring head and an emulsifying head, under the vacuum condition, firstly adjusting the rotating speed of the stirring head to be 20-60 r/min, the rotating speed of the emulsifying head is 30-800 r/min, alkyl glycoside aqueous solution with the mass fraction of 27% -38% is added into the reaction kettle, then citric acid is gradually added, in the process of adding the citric acid, the rotating speed of the emulsifying head is increased according to the acceleration of 100-200 r/min per minute, after the citric acid is added for 20-50 min, the rotating speed of the stirring head is adjusted to 80-120 r/min, the rotating speed of the emulsifying head is 13000-15000 r/min, then the hydrogen peroxide composite catalyst is added, reacting for 30-60 min under the conditions that the vacuum degree is 4000-8000 Pa and the temperature is 36-48 ℃ to obtain a mixed solution of alkyl glycoside citrate and alkyl glycoside; wherein the mass ratio of the added hydrogen peroxide composite catalyst to the alkyl glycoside is (1.5-10): 100, respectively; the hydrogen peroxide composite catalyst comprises ethylene diamine tetraacetic acid and hydrogen peroxide, and the mass ratio of the ethylene diamine tetraacetic acid to the hydrogen peroxide is (96-99): (1-4);
adjusting the rotating speed of the emulsifying head to be 800-1000 r/min again, adjusting the rotating speed of the stirring head to be 30-60 r/min, adding glycosyl amide quaternary ammonium salt and artemisinin extracting solution into the mixed solution, supplementing deionized water to 90% of the formula amount, adding a thickening agent, stirring for 30-60 min, uniformly mixing, adjusting the pH value to be 7.0-7.5, removing the vacuum in the reaction kettle, adjusting the vacuum to be normal pressure, adding other auxiliary agents and the rest deionized water, adjusting the rotating speed of the emulsifying head to be 300-500 r/min, adjusting the rotating speed of the stirring head to be 20-50 r/min, and continuously stirring for 30-50 min to obtain the mild sterilization laundry detergent;
wherein the thickening agent is sodium alginate, xanthan gum or pectin; the other auxiliary agents are one or the mixture of at least two of essence, fluorescent whitening agent, sodium hydroxide, potassium hydroxide and pigment;
the mild sterilization laundry detergent comprises the following components in parts by mass based on 100 parts by mass: 1.0-3.0 parts of alkyl glycoside citrate, 3.0-10.0 parts of alkyl glycoside, 1.5-2.5 parts of glycosyl amide quaternary ammonium salt, 1.5-3.0 parts of artemisinin extracting solution, 0.1-1 part of thickening agent, 0.1-5 parts of other auxiliary agents and the balance of deionized water.
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| CN103805367A (en) * | 2014-02-28 | 2014-05-21 | 刘菊 | High-efficiency sterilization laundry detergent |
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| CN103555450A (en) * | 2013-11-05 | 2014-02-05 | 中国日用化学工业研究院 | Antibacterial decontaminating liquid detergent and preparation method thereof |
| CN103805367A (en) * | 2014-02-28 | 2014-05-21 | 刘菊 | High-efficiency sterilization laundry detergent |
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| Title |
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| 烷基糖苷及其衍生物的技术进展;杨秀全等;《日用化学工业》;20120630;第42卷(第3期);第215页右栏2.3.1烷基糖苷柠檬酸酯 * |
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