CN108174875A - A kind of nanoscale thimerosal having no toxic side effect - Google Patents

A kind of nanoscale thimerosal having no toxic side effect Download PDF

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Publication number
CN108174875A
CN108174875A CN201810036432.6A CN201810036432A CN108174875A CN 108174875 A CN108174875 A CN 108174875A CN 201810036432 A CN201810036432 A CN 201810036432A CN 108174875 A CN108174875 A CN 108174875A
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thimerosal
edible alcohol
mixing
side effect
nanoscale
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崔建中
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Zhong Hong Nano Fiber Technology Danyang Co Ltd
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Zhong Hong Nano Fiber Technology Danyang Co Ltd
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Priority to CN201810036432.6A priority Critical patent/CN108174875A/en
Publication of CN108174875A publication Critical patent/CN108174875A/en
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
    • A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
    • A01N41/04—Sulfonic acids; Derivatives thereof
    • A01N41/08—Sulfonic acid halides; alpha-Hydroxy-sulfonic acids; Amino-sulfonic acids; Thiosulfonic acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/16—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Agronomy & Crop Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Fruits And Vegetables (AREA)

Abstract

The present invention proposes a kind of nanoscale thimerosal having no toxic side effect, and composition includes by weight percentage：The water of concentrate 10 20% and surplus；The composition of concentrate is as follows by weight percentage：Extract from fruit 60 75%, sulfamic acid 1 3%, C5H6Br2N2O2 3 7%, nano silver 0.08 2%, stearyl dimethyl benzyl ammonium chloride 2 4% and surplus water, the present invention can strong bactericidal, long acting antibiotic, use scope is extensive, safe without toxic side effect.

Description

A kind of nanoscale thimerosal having no toxic side effect
Technical field
The present invention relates to a kind of thimerosal, more particularly to a kind of nanoscale thimerosal having no toxic side effect.
Background technology
Foodsafety is the problem of current consumer compares concern, and fruits and vegetables are consumers eats wider food, What therefore the safety of this based food was just shown is increasingly important.Cleaning and sterilizing is the important process link of postharvest fruit and vegetable working process, Especially for the fresh-cut fruit and vegetable product quickly grown now, cleaning and sterilizing is even more very important.Effect is sterilized in cleaning process The quality of fruit directly influences the fresh-keeping quality of product and the edible safety of storage shelf life and consumer.
The taste that obtained thimerosal is usually directly diluted by disinfectant is more unpleasant, if it is desired to have disinfectant Pleasant fragranced then needs additionally to increase aromatic and bulking agent to realize, cumbersome cumbersome due to operating, and user is difficult Individually to complete, trouble is brought to user.
And since existing thimerosal contains more harmful chemicals element, use environment is single, can not directly apply to Human body can not also ensure that it sterilizes anti-microbial property.
Invention content
The present invention proposes a kind of nanoscale thimerosal having no toxic side effect regarding to the issue above, can strong bactericidal, long-acting Antibacterial, use scope is extensive, safe without toxic side effect.
Specific technical solution is as follows：
A kind of nanoscale thimerosal having no toxic side effect, composition include by weight percentage：Concentrate 10-20% and The water of surplus；
The composition of concentrate is as follows by weight percentage：
Extract from fruit 60-75%, sulfamic acid 1-3%, C5H6Br2N2O2 3-7%, nano silver 0.08-2%, octadecyldimethyl benzyl The water of ammonium chloride 2-4% and surplus.
Further, the extract from fruit is carried by weight percentage by the pomegranate of pineapple extracting solution 30-40% and surplus Liquid is taken to mix.
Further, the preparation method of the pineapple extracting solution is：
（1）After pineapple is cleaned stripping and slicing, it is broken into pineapple slurries；
（2）Mixed serum is obtained after edible alcohol mixing is added in pineapple slurries, by volume percentage, edible alcohol adds Enter the 5-12% that amount is pineapple slurries；
（3）Separating treatment is carried out to mixed serum using centrifuge, takes supernatant spare after separation；
（4）Edible alcohol is added in isolated slurry, by volume percentage, the addition of edible alcohol is slurry 20-40% stands 15-30min after mixing, carries out separating treatment to it using centrifuge, takes supernatant spare after separation；
（5）Repeat step（4）2-3 times；
（6）By step（3）（4）（5）Isolated supernatant after mixing, keeps the temperature 30- at a temperature of 70-80 DEG C 120min.
Further, the preparation method of the pomegranate extracting solution is：
（1）Pomegranate seed is taken to add in edible alcohol, is broken into pomegranate seed slurries, by weight percentage, the addition of edible alcohol 4-10% for pomegranate seed slurries；
（2）Mixed serum is obtained after citric acid mixing is added in pomegranate seed slurries, by weight percentage, the addition of citric acid The 0.5-3% for pomegranate seed slurries is measured,；
（3）Separating treatment is carried out to mixed serum using centrifuge, takes supernatant spare after separation；
（4）Edible alcohol is added in isolated slurry, by weight percentage, the addition of edible alcohol is slurry 20-40% stands 15-30min after mixing, carries out separating treatment to it using centrifuge, takes supernatant spare after separation；
（5）Repeat step（4）2-3 times；
（6）By step（3）（4）（5）Isolated supernatant after mixing, keeps the temperature 30- at a temperature of 70-80 DEG C 120min.
Further, the preparation method of concentrate is：By sulfamic acid, C5H6Br2N2O2, nanometer at a temperature of 40-60 DEG C After silver, stearyl dimethyl benzyl ammonium chloride and water stir evenly, room temperature is naturally cooled to, adds extract from fruit mixing Uniformly.
Further, the preparation method of thimerosal is：Concentrate and water are uniformly mixed at normal temperatures.
Beneficial effects of the present invention are：
The pure natural extraction of the present invention rich in natural fiavanoids and aliphatic acid, has potent antibacterial effect, the nontoxic secondary work to skin With without chemical noxious ingredient, securely and reliably.
The present invention has：（1）Heat resistance is strong, and 30min is heated at 100 DEG C, and anti-microbial property is constant；（2）Acid resistance is strong, Below PH3.0 anti-microbial properties are constant；（3）Alkali resistance is strong, and more than PH12.0 anti-microbial properties are constant.
The present invention is widely used, can be widely applied in utensil, food, skin and oral cavity sterilize.
Specific embodiment
For technical scheme of the present invention is made to be more clear clearly, below the present invention is described further, it is any to this The technical characteristic of inventive technique scheme carries out the scheme that equivalencing is obtained with conventional reasoning and each falls within the scope of the present invention.
Embodiment one
A kind of nanoscale thimerosal having no toxic side effect, composition include by weight percentage：Concentrate 15% and surplus Water；
The composition of concentrate is as follows by weight percentage：
Extract from fruit 65%, sulfamic acid 2%, C5H6Br2N2O2 4%, nano silver 1.2%, stearyl dimethyl benzyl ammonium chloride 3% With the water of surplus.
Further, the extract from fruit is extracted by weight percentage by the pomegranate of pineapple extracting solution 35% and surplus Liquid mixes.
Further, the preparation method of the pineapple extracting solution is：
（1）After pineapple is cleaned stripping and slicing, it is broken into pineapple slurries；
（2）Mixed serum is obtained after edible alcohol mixing is added in pineapple slurries, by volume percentage, edible alcohol adds Enter 8% that amount is pineapple slurries；
（3）Separating treatment is carried out to mixed serum using centrifuge, takes supernatant spare after separation；
（4）Edible alcohol is added in isolated slurry, by volume percentage, the addition of edible alcohol is slurry 25%, 20min is stood after mixing, separating treatment is carried out to it using centrifuge, takes supernatant spare after separation；
（5）Repeat step（4）3 times；
（6）By step（3）（4）（5）Isolated supernatant after mixing, keeps the temperature 60min at a temperature of 80 DEG C.
Further, the preparation method of the pomegranate extracting solution is：
（1）Pomegranate seed is taken to add in edible alcohol, is broken into pomegranate seed slurries, by weight percentage, the addition of edible alcohol 6% for pomegranate seed slurries；
（2）Mixed serum is obtained after citric acid mixing is added in pomegranate seed slurries, by weight percentage, the addition of citric acid 1.5% for pomegranate seed slurries is measured,；
（3）Separating treatment is carried out to mixed serum using centrifuge, takes supernatant spare after separation；
（4）Edible alcohol is added in isolated slurry, by weight percentage, the addition of edible alcohol is slurry 30%, 20min is stood after mixing, separating treatment is carried out to it using centrifuge, takes supernatant spare after separation；
（5）Repeat step（4）3 times；
（6）By step（3）（4）（5）Isolated supernatant after mixing, keeps the temperature 70min at a temperature of 80 DEG C.
Further, the preparation method of concentrate is：At a temperature of 50 DEG C by sulfamic acid, C5H6Br2N2O2, nano silver, After stearyl dimethyl benzyl ammonium chloride and water stir evenly, room temperature is naturally cooled to, it is equal to add extract from fruit mixing It is even.
Further, the preparation method of thimerosal is：Concentrate and water are uniformly mixed at normal temperatures.
Embodiment two
A kind of nanoscale thimerosal having no toxic side effect, composition include by weight percentage：Concentrate 12% and surplus Water；
The composition of concentrate is as follows by weight percentage：
Extract from fruit 75%, sulfamic acid 3%, C5H6Br2N2O2 6%, nano silver 0.5%, stearyl dimethyl benzyl ammonium chloride 2% With the water of surplus.
Further, the extract from fruit is carried by weight percentage by the pomegranate of pineapple extracting solution 30-40% and surplus Liquid is taken to mix.
Further, the preparation method of the pineapple extracting solution is：
（1）After pineapple is cleaned stripping and slicing, it is broken into pineapple slurries；
（2）Mixed serum is obtained after edible alcohol mixing is added in pineapple slurries, by volume percentage, edible alcohol adds Enter 12% that amount is pineapple slurries；
（3）Separating treatment is carried out to mixed serum using centrifuge, takes supernatant spare after separation；
（4）Edible alcohol is added in isolated slurry, by volume percentage, the addition of edible alcohol is slurry 40%, 30min is stood after mixing, separating treatment is carried out to it using centrifuge, takes supernatant spare after separation；
（5）Repeat step（4）3 times；
（6）By step（3）（4）（5）Isolated supernatant after mixing, keeps the temperature 80min at a temperature of 80 DEG C.
Further, the preparation method of the pomegranate extracting solution is：
（1）Pomegranate seed is taken to add in edible alcohol, is broken into pomegranate seed slurries, by weight percentage, the addition of edible alcohol 10% for pomegranate seed slurries；
（2）Mixed serum is obtained after citric acid mixing is added in pomegranate seed slurries, by weight percentage, the addition of citric acid 3% for pomegranate seed slurries is measured,；
（3）Separating treatment is carried out to mixed serum using centrifuge, takes supernatant spare after separation；
（4）Edible alcohol is added in isolated slurry, by weight percentage, the addition of edible alcohol is slurry 40%, 30min is stood after mixing, separating treatment is carried out to it using centrifuge, takes supernatant spare after separation；
（5）Repeat step（4）3 times；
（6）By step（3）（4）（5）Isolated supernatant after mixing, 30-120min is kept the temperature at a temperature of 70 DEG C .
Further, the preparation method of concentrate is：At a temperature of 55 DEG C by sulfamic acid, C5H6Br2N2O2, nano silver, After stearyl dimethyl benzyl ammonium chloride and water stir evenly, room temperature is naturally cooled to, it is equal to add extract from fruit mixing It is even.
Further, the preparation method of thimerosal is：Concentrate and water are uniformly mixed at normal temperatures.

Claims (6)

1. a kind of nanoscale thimerosal having no toxic side effect, it is characterized in that, composition includes by weight percentage：Concentration The water of liquid 10-20% and surplus；
The composition of concentrate is as follows by weight percentage：
Extract from fruit 60-75%, sulfamic acid 1-3%, C5H6Br2N2O2 3-7%, nano silver 0.08-2%, octadecyldimethyl benzyl The water of ammonium chloride 2-4% and surplus.
2. a kind of nanoscale thimerosal having no toxic side effect as described in claim 1, it is characterized in that, the extract from fruit is pressed Weight percent meter is mixed by the pomegranate extracting solution of pineapple extracting solution 30-40% and surplus.
3. a kind of nanoscale thimerosal having no toxic side effect as claimed in claim 2, it is characterized in that, the pineapple extracting solution Preparation method is：
（1）After pineapple is cleaned stripping and slicing, it is broken into pineapple slurries；
（2）Mixed serum is obtained after edible alcohol mixing is added in pineapple slurries, by volume percentage, edible alcohol adds Enter the 5-12% that amount is pineapple slurries；
（3）Separating treatment is carried out to mixed serum using centrifuge, takes supernatant spare after separation；
（4）Edible alcohol is added in isolated slurry, by volume percentage, the addition of edible alcohol is slurry 20-40% stands 15-30min after mixing, carries out separating treatment to it using centrifuge, takes supernatant spare after separation；
（5）Repeat step（4）2-3 times；
（6）By step（3）（4）（5）Isolated supernatant after mixing, keeps the temperature 30- at a temperature of 70-80 DEG C 120min.
4. a kind of nanoscale thimerosal having no toxic side effect as claimed in claim 2, it is characterized in that, the pomegranate extracting solution Preparation method is：
（1）Pomegranate seed is taken to add in edible alcohol, is broken into pomegranate seed slurries, by weight percentage, the addition of edible alcohol 4-10% for pomegranate seed slurries；
（2）Mixed serum is obtained after citric acid mixing is added in pomegranate seed slurries, by weight percentage, the addition of citric acid The 0.5-3% for pomegranate seed slurries is measured,；
（3）Separating treatment is carried out to mixed serum using centrifuge, takes supernatant spare after separation；
（4）Edible alcohol is added in isolated slurry, by weight percentage, the addition of edible alcohol is slurry 20-40% stands 15-30min after mixing, carries out separating treatment to it using centrifuge, takes supernatant spare after separation；
（5）Repeat step（4）2-3 times；
（6）By step（3）（4）（5）Isolated supernatant after mixing, keeps the temperature 30- at a temperature of 70-80 DEG C 120min.
5. a kind of nanoscale thimerosal having no toxic side effect as described in claim 1, it is characterized in that, the preparation method of concentrate For：Sulfamic acid, C5H6Br2N2O2, nano silver, stearyl dimethyl benzyl ammonium chloride and water are stirred at a temperature of 40-60 DEG C After mixing uniformly, room temperature is naturally cooled to, extract from fruit is added and is uniformly mixed.
6. a kind of nanoscale thimerosal having no toxic side effect as described in claim 1, it is characterized in that, the preparation method of thimerosal For：Concentrate and water are uniformly mixed at normal temperatures.
CN201810036432.6A 2018-01-15 2018-01-15 A kind of nanoscale thimerosal having no toxic side effect Pending CN108174875A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579702A (en) * 2012-03-14 2012-07-18 山东赛克赛斯药业科技有限公司 Medicine for treating dental ulcer and preparation method thereof
CN104522050A (en) * 2015-01-07 2015-04-22 安徽瀚驰生物科技有限公司 Composite bactericide of nano-silver and polyhexamethylene guanidine and processing technology of composite bactericide
CN106135296A (en) * 2016-06-30 2016-11-23 广东三和化工科技有限公司 A kind of environment-friendlydisinfectant disinfectant and preparation method thereof
CN106212551A (en) * 2016-07-29 2016-12-14 腾科宝迪（厦门）生物科技有限公司 A kind of daily non-stimulated disinfectant and preparation method thereof
CN106798716A (en) * 2017-02-22 2017-06-06 上海纳米技术及应用国家工程研究中心有限公司 Leave nanometer silver antimicrobial hand cleanser

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579702A (en) * 2012-03-14 2012-07-18 山东赛克赛斯药业科技有限公司 Medicine for treating dental ulcer and preparation method thereof
CN104522050A (en) * 2015-01-07 2015-04-22 安徽瀚驰生物科技有限公司 Composite bactericide of nano-silver and polyhexamethylene guanidine and processing technology of composite bactericide
CN106135296A (en) * 2016-06-30 2016-11-23 广东三和化工科技有限公司 A kind of environment-friendlydisinfectant disinfectant and preparation method thereof
CN106212551A (en) * 2016-07-29 2016-12-14 腾科宝迪（厦门）生物科技有限公司 A kind of daily non-stimulated disinfectant and preparation method thereof
CN106798716A (en) * 2017-02-22 2017-06-06 上海纳米技术及应用国家工程研究中心有限公司 Leave nanometer silver antimicrobial hand cleanser

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* Cited by examiner, † Cited by third party
Title
张流波等: "《医学消毒学最新进展》", 31 December 2015, 人民军医出版社 *
张立华等: "石榴不同部位提取物抗油脂氧化及抑菌活性的比较", 《中国粮油学报》 *

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