CN108114112A - A kind of blood-activating analgetic plaster and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of blood-activating analgetic plasters, it is by Radix Angelicae Sinensis, Caulis Spatholobi, Radix Angelicae Pubescentis, monkshood, radix aconiti agrestis, turpentine, lycopodium calvatum, pawpaw, lopseed, ground bettle, flying worm, full worm, rhizoma typhonii, dragon's blood, safflower, peach kernel, frankincense, myrrh, semen momordicae is formed according to certain weight proportion, by sorting, it impregnates, it refines, distillation, oil refining, lower pellet, it releases fire-toxin, go dryness evil, unpacking, beach is made, with promoting blood circulation and removing blood stasis, relaxing tendons and activating collaterals, it is warming channel and expelling cold, dispelling wind and eliminating dampness, swelling and pain relieving, the effect of strengthening muscles and bones, traumatic injury can effectively be treated, rheumathritis, caput femoris necrosis etc..

Description

A kind of blood-activating analgetic plaster and preparation method thereof

Technical field

The present invention relates to a kind of pharmaceutical technology fields, and in particular to a kind of to treat traumatic injury, rheumatic arthritis, femur The blood-activating analgetic plaster of head necrosis.The invention further relates to the preparation methods of the Chinese medicinal ointment.

Background technology

The diseases such as traumatic injury, rheumathritis, caput femoris necrosis are since qi and blood is not at prolonged joint, muscles and bones Logical, channels and collaterals are obstructed, and joint, muscles and bones lose body swelling, pain caused by flourish or Acute and chronic inflammation etc..So that patient articular Bitterly, redness, inflammation, even activity be obstructed, function limitation, normally life and sleep, severe patient are even raw for the lighter's ache influence Work cannot take care of oneself, and bring pain to patient, while also add burden to household.

For a long time, arthralgia, traumatic injury etc. are considered as indisposition, are carried no weight, and wait arthritis, the stock of development The situation of head necrosis just causes patient and household's note that still at this moment can only often be alleviated with the drug of anti-inflammatory, analgesic The slight illness of patient can not thoroughly treat the disease of patient, palliative, easily recur.Such disease group is vast in society, right There is also extensive demands on this kind of drug and curative effect.

The content of the invention

The object of the present invention is to provide a kind of Chinese medicinal ointment, the Chinese medicinal ointment for treatment traumatic injury, rheumatic arthritis, Caput femoris necrosis, which has, treats both principal and secondary aspect of disease, is quick, evident in efficacy, cheap, the characteristics of having no toxic side effect.

It is a further object of the present invention to provide the preparation methods of the blood-activating analgetic plaster.

Inventor observes traumatic injury, rheumatic arthritis, caput femoris necrosis to trouble in clinical treatment practice for many years The pain that person brings, according to the rule of development of the illness and the combination principle of Chinese medicine, and by substantial amounts of clinical verification, instead Multiple Exploration and conclusion goes out a kind of new formula of blood-activating analgetic plaster, present invention selection Radix Angelicae Sinensis, Caulis Spatholobi, Radix Angelicae Pubescentis, monkshood, radix aconiti agrestis, turpentine, Lycopodium calvatum, pawpaw, lopseed, ground bettle, flying worm, full worm, rhizoma typhonii, dragon's blood, safflower, peach kernel, frankincense, myrrh, semen momordicae into Row combination, by these drugs by sorting, immersion, refinement, distillation, oil refining, it is lower it is red, release fire-toxin, go dryness evil, unpacking, beach system Into blood-activating analgetic plaster so that each efficacy of drugs generates synergistic effect, with promoting blood circulation and removing blood stasis, swelling and pain relieving, strengthens muscles and bones Effect, so as to effectively treat traumatic injury, rheumatic arthritis, caput femoris necrosis.

The effect of drug in the present invention：

Wherein：

Radix Angelicae Sinensis：For the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Nature and flavor：Sweet, It is pungent, bitter, temperature.Return liver, the heart, the spleen channel.Effect：It enriches blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.Radix Angelicae Sinensis Central nervous system has suppression It makes and uses, volatile oil has the effects that calmness, hypnosis, analgesia, anesthesia.For blood deficiency chlorosis, dizziness palpitaition, asthenia cold abdominalgia, rheumatism Numbness pain, injury from falling down, ulcer sores.According to《Book on Chinese herbal medicine is just》It carries：" its is sweet in flavor and weighs, therefore can specially enrich blood, and gas is light and pungent, therefore again can Promoting circulation of blood, can support nutrition blood, tonifying Qi production of sperm, five viscera settling, strengthen body, beneficial mind, and all tangible deficient diseases are omni-benefiting." modern times doctor Learning research confirms, Radix Angelicae Sinensis has antibacterial, antiinflammation, and Radix Angelicae Sinensis hot water extract is bright to having during chronic articular rheumatism acute attack Aobvious inhibitory action.

Caulis Spatholobi：For the dry of pulse family Leguminosae plant spatholobus suberectus Spatholobus suberectusDunn Dry rattan.Nature and flavor：Bitter, sweet, warm.Return liver and kidney channel.Effect：It enriches blood, invigorates blood circulation, dredging collateral.This product promoting circulation of blood blood-nourishing, relaxing tendons and activating collaterals, to control Treatment passages through which vital energy circulates is not smooth, the common medicine of channels discord disease.

Radix Angelicae Pubescentis：For samphire Angelica pubescens Angelica pubescens Maxim. f. biserrata The dry root of Shan et Yuan.Nature and flavor：It is pungent, bitter, tepor.Return kidney, bladder warp.Effect：Dispelling wind and eliminating dampness, numbness relieving and pain relieving.For Wind-cold-dampness arthralgia, lumbocrural pain, few the moon volt wind headache.Clinically it is usually used in expelling wind and eliminating dampness, numbness relieving and pain relieving, all wind-cold-dampness arthralgias, joint Pain, it is no matter new long, it can apply, especially using diseases such as the numbness pain of lower part, soreness of waist and knee joint, two atrophy numbness, joint stuffiness to be suitable.

Monkshood：For dry female root of ranunculaceae plant rhizome of Chinese monkshood Aconitum carmichaeli Debx..Nature and flavor：Pungent, Hardship, heat；It is very toxic.The thoughts of returning home, liver,kidney,spleen warp.Effect：Dispelling wind and eliminating dampness, antalgic.For wind-cold-dampness arthralgia, arthralgia, the heart Abdomen crymodynia, cold hernia are had a pain, narcotic analgesic.

Radix aconiti agrestis：For the dried root of ranunculaceae plant north rhizome of Chinese monkshood Aconitum kusnezoffii Reichb..Nature and flavor： It is pungent, bitter, heat；It is very toxic.The thoughts of returning home, liver,kidney,spleen warp.Effect：Dispelling wind and eliminating dampness, antalgic.For wind-cold-dampness arthralgia, arthralgia, Trusted subordinate's crymodynia, cold hernia are had a pain, narcotic analgesic.

Turpentine：For the knot of pinaceae plant Pinus tabulaeformis tabulaeformis Carr, masson pine or the limb of pinus yunnanensis Section.Nature and flavor：Hardship, temperature.Distributed in heart and lung channels.Major function：Dispelling wind and eliminating dampness, active pain relieving.For rheumatic arthritis, pain in waist and lower extremities, big bone Section disease, treating swelling and pain by traumatic injury.《Collected statements on the herbal foundation》：Turpentine, temperature is dry, and such as sufficient knee muscles and bones has wind to have wet, acid of having a pain, and impotence is weak powerless Person is stood with this and fullyed recover from an illness.If deficiency of Yin marrow is weary, blood is dry fiery person, preferably considers and uses it.

Lycopodium calvatum：For the herb of Lycopodiaceae Lycopodium plant lycopod Lycopodium japonicum Thunb..Nature and flavor： It is bitter, pungent, warm.Return liver warp.Effect：Dispelling wind and eliminating dampness, relaxing tendons and activating collaterals.For wind-cold-dampness arthralgia, muscle arteries and veins contraction pain carbuncle.Bruise torsion is controlled in external application Wound swelling and pain.

Pawpaw：For rosaceous plant chaenomeles lagenaria Chaenomeles speciosa（Sweet）The drying of Nakai closely into Ripe fruit.Nature and flavor：Acid, temperature.Return liver, the spleen channel.Effect：Relaxing tendons and activating collaterals, stomach dampness elimination.Pawpaw has the work of preferable relaxing tendons and activating collaterals With, and the stopping numbness pain that can dehumidify, to control the key medicine of arthritis with fixed pain caused by dampness, spasm of muscles and vessels.Being generally used for soreness of waist and knee joint when controlling arthralgia pain due to rheumatism, person is in the majority, Often with the adapteds such as tiger bone.To control the key medicine for convulsion of vomiting and diarrhoea.For summer-heat and damp cholera, the disease for convulsion of vomiting and diarrhoea, can compatibility coix seed, bite The medicines such as sand, the coptis, evodia rutaecarpa are the same as use.Research shows with separation and Extraction pawpaw phenol in pawpaw water-soluble portion through extracorporeal bacteria inhibitor test It proves, bacteriostasis is apparent.

Lopseed：For Euphorbiaceae Speranskia plant speranskia tuberculata Speranskia tuberculata（Bunge） Baill., Balsaminaceae herbaceous plant balsamine Impatiens balsamina L., Bignoniaceae Chinese Incarvilla Herb platymiscium Chinese Incarvilla Herb Incarvillea sinensis Lam., pulse family Vetch plant vicia amoena Vicia amoena Fisch. herb and Ericaceae Gaultheria plant Caulis et folium gaultheriae yunnanensis Gaultheria yunnanensis（Franch.）Rehd. complete stool.Nature and flavor： It is pungent, bitter, temperature.It is slightly poisonous.Return liver and kidney channel.Effect：Dispelling wind and eliminating dampness, removing toxic substances analgesic.Main arthralgia pain due to rheumatism；Muscles and bones contracture；Cold-dampness foot Gas；Lumbar strain；Paralysis；Amenorrhoea；Eczema of scrotum；Sore furuncle poison.It is no matter new long with arthralgia pain due to rheumatism is controlled, it can apply.It can coordinate Cortex acanthopanacis, caulis lonicerae, Pine Nodular Branch, the root of Chinese clematis will be the same as use.For traumatic injury, the stagnant pain of the stasis of blood or women's amenorrhea, can coordinate The medicines such as Radix Angelicae Sinensis, peach kernel, Herba Lycopi are the same as use.In addition this product can also treat boil carbuncle swells, snakebite and bugbite, can be appropriate with fresh grass, batter down outer It applies.

Ground bettle：For Corydiidae eupolyphagasinensis walker Eupolyphaga sinensis Walker or polyphagaplancyi Stelephaga The female adult of plancyi (Boleny) is all.Nature and flavor：It is cold, it is salty；It is slightly poisonous.Return liver warp.Effect：Broken stasis of blood blood, continuous muscles and bones, for controlling Treat traumatic injury, injury of tendon and muscle fracture, pain caused by ecchymoma.This product it is salty-cold enter blood, it is main enter Liver Channel, property is apt to walk to alter, can activating blood circulation and reducing swelling analgesic, continue Muscle synthetism is cured the wound, and is traumatology common medicine, is chiefly used in the injury of tendon and muscle of fracturing, blood stasis and swelling pain especially.

Flying worm：Scientific name stiff silkworm is that the larva in 4~5 ages of Bombycidae insect silkworm Bombyx mori Linnaeus. infects （Or artificial infection）Muscardine Beauveria bassiana（Bals.）Vuillant and lethal larva hirudo leech.Nature and flavor： It is salty, pungent, it puts down.Return liver, lung, stomach.Effect：It expels endogenous wind to relieve convulsion, reducing phlegm and resolving masses.It cures mainly：Apoplectic aphasia, middle tuyere nose eye are oblique.

Full worm：Scientific name scorpio is the hirudo leech of Buthidae animal buthus martensii Karscs Buthus martensii Karsch.Property Taste：It is pungent, flat, toxic.Return liver warp.Effect：Ceases wind antispastic, dispersing pathogen accumulation are removed obstruction in channels to relieve pain.For child convulsion, spasm of twitching, in Air port is askew, hemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.This product, which can detoxify, dissipates poison and dredging collateral Analgesic, can adapted no matter oral administration and externally.Often with centipede, stiff silkworm with use.This product is heated to 100 DEG C, and 30min, toxin can disappear It removes.Scorpio master enters Liver Channel, can calm down liver wind and wind and removing obstruction in channels, has good Inflammation Zhijing effect, various available for treating Spasm caused by reason is twitched, and with the high fever for controlling pediatric acute convulsion, is often equal with Rhizoma Gastrodiae, stiff silkworm and is used.

Rhizoma typhonii：For the dry tuber of aroid Typhonium giganteum Typhonium giganteum Engl..Nature and flavor： It is pungent, warm, toxic.Return stomach, Liver Channel.Effect：Wind-dispelling phlegm, arresting convulsion are jerked, detoxicating and resolving a mass analgesic.For heap soil or fertilizer over and around the roots of apoplexy phlegm, facial paralysis, language Say puckery stuttering, phlegm and headache, migraine and general headache, larynx numbness pharyngalgia, lockjaw；Control scrofula subcutaneous nodule, venomous snake bite, lockjaw, carbuncle swells outside.

Dragon's blood：For the processed system of resin of babassu Sanguis Draxonis Daemonorops draco Blume. fruits exudation Into.Nature and flavor：It is sweet, salty, it puts down.Converge to heart and liver channels.Effect：Removing blood stasis and relieving pain, hemostasia and promoting granulation.It is lost for falling to flutter, internal injury stasis caused pain；Wound Haemophilia.《Detailed outline》Described in：" black horse Lin exhausts, the fat liquid of wood, such as the human fat and blood of people, sweet-salty and walk blood, lid brothers faint cloudy medicine .Liver and all main blood Gu Er of pericardium.Interchannel Liu Shi clouds, dragon's blood are and the panacea of blood are except blood pain.Frankincense, myrrh, though main blood Disease, and it is simultaneous enter qi leel, this is then specially in blood system person ".

Safflower：For the tubular corolla of feverfew safflower Carthamus tinctorius L..Nature and flavor：Temperature, it is pungent.The thoughts of returning home, Liver Channel.Effect：Invigorate blood circulation, removing blood stasis and analgesics.The pungent scattered temperature of safflower is logical, specially enters blood system, energy promoting blood circulation, promoting menstruation tune arteries and veins, Chang Yutao The mutual reinforcements between such as benevolence, Radix Angelicae Sinensis, Rhizoma Chuanxiong are use.Safflower has expansion blood vessel function.Carthamin yellow can be obviously prolonged blood plasma recalcification time, coagulate Blood zymogen time and clotting time.

Peach kernel：For rosaceous plant peach Prunus persica（L.）Batsch or mountain peach Prunus davidiana （Carr.）Franch. dry mature seed.Nature and flavor：Bitter, sweet, flat.The thoughts of returning home, liver, large intestine channel.Effect：Promoting blood circulation, ease constipation Defaecation, it is relieving cough and asthma.The power of peach kernel dissolving stasis is stronger, also known as stasis-breaking drug, for treating blood stasis, wei lumps in the abdomen, often with safflower, Radix Angelicae Sinensis.Peach Benevolence blocks blood flow, blood obstacle has improvement result, each internal organs each group can be made to knit functional recovery normal.

Frankincense：For Burseraceae Boswellia carterii platymiscium Boswellia carterii Boswellia carterii Birdw. [B. sacra Fluek.], the fragrant tree B. bhawdajiana Birdw. of medicine glue and its resin of congener skin zone exudation.Nature and flavor：Pungent, bitter, Temperature.The thoughts of returning home, liver, the spleen channel.Effect：Promoting blood circulation and stopping pain, detumescence and promoting granulation.This product be used for sore after do not close up long, often with myrrh compatibility, It is externally applied to affected part.

Myrrh：For Burseraceae myrrh platymiscium myrrh Commiphora myrrha Engl. [C. molmol Engl.] And it belongs to him together and plants the oleo-gum-resin of the trunk skin zone exudation of plant.Nature and flavor：It is bitter, flat.Enter Liver Channel.Effect：Blood stasis eliminatings are dissipated, detumescence is fixed Bitterly.It can be clinically used for treatment acute mastitis.

Semen momordicae：For cucurbitaceous plant Momordica cochinchiensis Momordica cochinchinensis（Lour.）Spreng. dry Dry mature seed.Nature and flavor：Bitter, micro-sweet, it is cool；It is toxic.Return liver, spleen, stomach.Effect：Mass dissipating and swelling eliminating attacks poison and treats sore.For sore Pyogenic infections, acute mastitis, scrofula, anal fistula, chronic eczema, the favus of the scalp.《Essentials of Materia Medica》：It purges heat, sore is controlled in external application, and profit large intestine controls rush down dysentery infantile malnutrition due to digestive disturbances or intestinalparasites.Scrofula Sore hemorrhoid, acute mastitis, freshwater mussel poison.Detumescence chases after poison.

Using above-mentioned technical proposal, the beneficial effects of the invention are as follows：Radix Angelicae Sinensis, Caulis Spatholobi replenishing and activating blood are removed obstruction in channels to relieve pain, solely Work, monkshood, radix aconiti agrestis dispelling wind and eliminating dampness, antalgic, the more than five tastes are monarch drug in a prescription, directly act on affected part and patient's progress wind-dispelling is removed Wet, antalgic, qi and blood of the reduction of patient caused by disease is obstructed, and channels and collaterals are obstructed, and the pain caused by honor is lost in joint, muscles and bones Bitterly, the symptoms such as redness, turpentine active pain relieving, lycopodium calvatum, pawpaw relaxing tendons and activating collaterals, lopseed removing toxic substances analgesic, more than several tastes be ministerial drug, Enhance monarch drug in a prescription drug effect, accelerate the elimination of redness, inflammation, pain, help with other all medicines, play dispelling wind and eliminating dampness, promoting blood circulation and removing blood stasis, dredging collateral altogether The benefits of analgesic, the made plaster of the present invention, in patient body-surface acupuncture point, its promoting blood circulation and removing blood stasis, relaxing muscles and tendons are played by channels and collaterals with drug effect The effect of dredging collateral, warming channel and expelling cold, dispelling wind and eliminating dampness.

Medicine material dosage of the present invention is largely groped summary through inventor's progress and is drawn, each raw material dosage is following Parts by weight scope, which all has, to be had a better effect：Radix Angelicae Sinensis 25-35g, Caulis Spatholobi 45-55g, Radix Angelicae Pubescentis 25-35g, monkshood 50-70g, radix aconiti agrestis 50-70g, turpentine 25-35g, lycopodium calvatum 25-35g, pawpaw 10-20g, lopseed 25-35g, ground bettle 25-35g, flying worm 25- 35g, full worm 25-35g, rhizoma typhonii 10-20g, dragon's blood 25-35g, safflower 10-20g, peach kernel 15-25g, frankincense 30-40g, myrrh 30-40g, semen momordicae 25-35g.

Wherein it is preferably：Radix Angelicae Sinensis 30g, Caulis Spatholobi 50g, Radix Angelicae Pubescentis 30g, monkshood 60g, radix aconiti agrestis 60g, turpentine 30g, lycopodium calvatum 30g, pawpaw 15g, lopseed 30g, ground bettle 30g, flying worm 30g, full worm 30g, rhizoma typhonii 15g, dragon's blood 30g, safflower 15g, peach Benevolence 20g, frankincense 35g, myrrh 35g, semen momordicae 30g.

The present invention is also added into remaining blood, centipede, Moschus, borneol.

More than blood：This product is carbide made of human hair.Nature and flavor：Hardship is put down.Return liver, stomach.Effect：Hemostasis, stagnation resolvation.For It spits blood, spitting of blood, bleeding from five sense organs or subcutaneous tissue, hematuria, metrostaxis, traumatic hemorrhage.

Centipede：For Scolopendridae animal Scolopendpa Subspinipes Mutilans L. KOCH Scolopendra subspinipes mutilans L. Koch's Hirudo leech.Nature and flavor：It is pungent, warm, toxic.Return liver warp.Effect：Ceases wind antispastic, work(poison dissipating bind, removes obstruction in channels to relieve pain.For child convulsion, take out It jerks spasm, middle air port is askew, hemiplegia, lockjaw, rheumatoid arthritis stubborn, sore, scrofula, venomous snake bite.This product pungent-warm is toxic, and property is apt to It walks to alter, it is dry strong violent, often it is use with scorpio mutual reinforcement between in row expression.

Moschus：For the secretion in animal in deer family woods musk deer, horse musk deer or the ripe male body note capsule of former musk deer.Nature and flavor：It is pungent, warm.The thoughts of returning home, The spleen channel.Effect：Inducing resuscitation of having one's ideas straightened out, invigorate blood circulation, swelling and pain relieving.Moschus pungent-warm, air exhaustion are fragrant, and it is very strong to walk the property altered, and has very strong Have one's ideas straightened out the logical effect for closing inducing resuscitation, be the key medicine of inducing resuscitation of having one's ideas straightened out.

Borneol：For Spore density Borneolum Syntheticum resin processed goods or be that camphor, turpentine oil etc. chemically synthesize Be processed into product.Nature and flavor：It is pungent, bitter, it is slightly cold.The thoughts of returning home, spleen, lung channel.Effect：Inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain.For pyreticosis god Dusk, convulsion are fainted, apoplexy coma due to blocking of the respiratory system, bstruction of the circulation of vital energy is fainted cruelly, middle evil is gone into a coma, hot eyes, aphtha, abscess of throat, and duct is suppurated.This product has heat-clearing solution Poison, the effect of erosion prevention and muscle growing, can control burn and scald.

It is added enter medicinal material parts by weight it is as follows：4-9g, centipede 3-9g, Moschus 0.03-0.1g, borneol 0.1-0.3g more than blood.

It is wherein preferred：6g, centipede 6g, Moschus 0.06g, borneol 0.2g more than blood.

The effect that blood is remaining, centipede can enhance dissolving stasis is added in prescription, promotes the opening of affected part stasis blocking, increases Moschus and ice Piece, not only can with flavouring, can also invigorate blood circulation, accelerate Medicated Permeation to affected part, promote the recovery of patient.

A kind of preparation method of blood-activating analgetic plaster, which is characterized in that preparation method is as follows：

Step 1: it impregnates：By weight proportion of the present invention, first by Radix Angelicae Sinensis, Caulis Spatholobi, Radix Angelicae Pubescentis, monkshood, radix aconiti agrestis, turpentine, lycopodium calvatum, Pawpaw, lopseed, ground bettle, flying worm, full worm, rhizoma typhonii, dragon's blood, safflower, peach kernel, frankincense, myrrh, semen momordicae are put into sesame oil It impregnates, it is spring and summer five days, seven days autumn and winter, spare；

Step 2: it refines：By soaked drug in step 1 and sesame oil with slow boiling tanning 4 it is small when, and have peach, mulberry, Chinese scholartree, willow, Until medicinal material is withered and yellow when floating over liquid level, the removal dregs of a decoction are filtered from fire for elm, five stirrings, spare；

Step 3: distillation：Filtered medicine oil in step 2 to be inserted again in refining container, addition blood is remaining, centipede medicinal material, then It is refined one hour with slow boiling, then the filtering removal dregs of a decoction, spare；

Step 4: oil refining：Filtered medicine oil in step 3 is inserted in refining container, experienced medicine oil is endured to dropping into a bead with slow boiling Shape, it is spare；

Step 5: lower pellet：By the medicine oil in step 4, heating with high heat is lower red again, and red lead is worn into fine powder, is uniformly spread in the oil, And stirred 5 to 8 minutes with five up times, when dense smoke emits most, use slow boiling instead and continue stirring tanning 5 to 15 minutes, lotion color and luster In it is shiny black when can be spare from fire；

Step 6: it releases fire-toxin：Boiled plaster in step 5 is poured into the well water got ready, impregnates three to five days and changes water daily Once, it is spare；

Step 7: go dryness evil：The plaster soaked in step 6 is dried in the shade, is packed into terrine, is sealed with beeswax and fills mouth, embedment is shady and cool Cellar is put within 7 to 10th at dry 15, it is spare；

Step 8: unpacking：By in step 7 in terrine nature and flavor, smell, color and luster have reached requirement plaster take out separately storage, It is spare；

Step 9: stand medicine：The fine medicinal material stirring of Moschus, borneol, dragon's blood will be added after plaster block water-bath fusing in step 8 Plaster is uniformly applied to after uniformly with bamboo chip cotton, i.e. usable on dogskin.

The present invention is not only easy to use compared with common Chinese prescription, and by directly acting on affected part, sends out faster Curative effect is waved, the oxidation of effective ingredient and red lead is leached by sesame oil, improves enlivening for traditional Chinese medicine ingredients to greatest extent Property and drug penetrating power, reach quick promoting blood circulation and removing blood stasis, channels sootheing and network vessel quickening, warming channel and expelling cold, dispelling wind and eliminating dampness, swelling and pain relieving, strong The effect of muscle zhuanggu, can effectively treat traumatic injury, rheumatic arthritis, caput femoris necrosis.

The present invention an important feature be：From selection to tanning, from tanning to refinement, shaping is finally arrived, all using only Special technique, these boil the road for the yin-yang and five elements for embodying Chinese Medicine culture in processes everywhere.Its value of blood-activating analgetic plaster Inner disease outer treat, the outer therapeutic features controlled of outer disease of the traditional Chinese medical science are even more shown, since plaster acts on human skin, so extracting Fragrant odour is mainly extracted during medicinal material and kills the strong authentic medicinal herbs of power thoroughly, and is subject to the medicine of channel tropism to lead its medicine, loosing the interspaces of skin and muscles, thoroughly Key hole, opening block and activating stagnancy make drug preferably through lesion, therefore blood-activating analgetic plaster has anti-inflammatory analgetic, relaxes through dredging collateral, and wind-dispelling dissipates The effect of cold, promoting blood circulation and removing blood stasis.The drug in plaster simultaneously with resuscitation with aromatics can stimulate nerves reaction by pore, can adjust Body function promotes antibody to be formed, so as to improve the immunity of the human body.

Specific embodiment

Embodiment one, Radix Angelicae Sinensis 25g, Caulis Spatholobi 45g, Radix Angelicae Pubescentis 25g, monkshood 50g, radix aconiti agrestis 50g, turpentine 25g, lycopodium calvatum 25g, Pawpaw 10g, lopseed 25g, ground bettle 25g, flying worm 25g, full worm 25g, rhizoma typhonii 10g, dragon's blood 25g, safflower 10g, peach kernel 15g, frankincense 30g, myrrh 30g, semen momordicae 25g.

Step 1: it impregnates：By above-mentioned weight proportion, first by Radix Angelicae Sinensis, Caulis Spatholobi, Radix Angelicae Pubescentis, monkshood, radix aconiti agrestis, turpentine, stretch muscle Grass, pawpaw, lopseed, ground bettle, flying worm, full worm, rhizoma typhonii, dragon's blood, safflower, peach kernel, frankincense, myrrh, semen momordicae are put into eight It is impregnated in jin sesame oil, it is spring and summer five days, seven days autumn and winter, spare；

Step 2: it refines：By soaked drug in step 1 and sesame oil with slow boiling tanning 4 it is small when, and have peach, mulberry, Chinese scholartree, willow, Until medicinal material is withered and yellow when floating over liquid level, the removal dregs of a decoction are filtered from fire for elm, five stirrings, spare；

Step 3: distillation：Filtered medicine oil in step 2 is inserted again in refining container, add in 4g, centipede 3g medicines more than blood Material, then refined one hour with slow boiling, then the filtering removal dregs of a decoction, spare；

Step 4: oil refining：Filtered medicine oil in step 3 is inserted in refining container, experienced medicine oil is endured to dropping into a bead with slow boiling Shape, it is spare；

Step 5: lower pellet：By the medicine oil in step 4, heating with high heat is lower red again, and three jin of red leads are worn into fine powder, are uniformly sprinkling upon It in oil, and is stirred 5 to 8 minutes with five up times, when dense smoke emits most, uses slow boiling instead and continue stirring tanning 5 to 15 minutes, lotion Color and luster can be spare from fire when being in shiny black；

Step 6: it releases fire-toxin：Boiled plaster in step 5 is poured into the well water got ready, impregnates three to five days and changes water daily Once, it is spare；

Step 7: go dryness evil：The plaster soaked in step 6 is dried in the shade, is packed into terrine, is sealed with beeswax and fills mouth, embedment is shady and cool Cellar is put within 7 to 10th at dry 15, it is spare；

Step 8: unpacking：By in step 7 in terrine nature and flavor, smell, color and luster have reached requirement plaster take out separately storage, It is spare；

Step 9: stand medicine：Moschus 0.03g, borneol 0.1g, dragon's blood 25g will be added after plaster block water-bath fusing in step 8 Plaster is uniformly applied to cotton, i.e. usable on dogskin by fine medicinal material with bamboo chip after stirring evenly.

Embodiment two, Radix Angelicae Sinensis 30g, Caulis Spatholobi 50g, Radix Angelicae Pubescentis 30g, monkshood 60g, radix aconiti agrestis 60g, turpentine 30g, lycopodium calvatum 30g, Pawpaw 15g, lopseed 30g, ground bettle 30g, flying worm 30g, full worm 30g, rhizoma typhonii 15g, dragon's blood 30g, safflower 15g, peach kernel 20g, frankincense 35g, myrrh 35g, semen momordicae 30g.

Step 1: it impregnates：By above-mentioned weight proportion, first by Radix Angelicae Sinensis, Caulis Spatholobi, Radix Angelicae Pubescentis, monkshood, radix aconiti agrestis, turpentine, stretch muscle Grass, pawpaw, lopseed, ground bettle, flying worm, full worm, rhizoma typhonii, dragon's blood, safflower, peach kernel, frankincense, myrrh, semen momordicae are put into eight It is impregnated in jin sesame oil, it is spring and summer five days, seven days autumn and winter, spare；

Step 2: it refines：By soaked drug in step 1 and sesame oil with slow boiling tanning 4 it is small when, and have peach, mulberry, Chinese scholartree, willow, Until medicinal material is withered and yellow when floating over liquid level, the removal dregs of a decoction are filtered from fire for elm, five stirrings, spare；

Step 3: distillation：Filtered medicine oil in step 2 is inserted again in refining container, add in 6g, centipede 6g medicines more than blood Material, then refined one hour with slow boiling, then the filtering removal dregs of a decoction, spare；

Step 4: oil refining：Filtered medicine oil in step 3 is inserted in refining container, experienced medicine oil is endured to dropping into a bead with slow boiling Shape, it is spare；

Step 5: lower pellet：By the medicine oil in step 4, heating with high heat is lower red again, and three jin of red leads are worn into fine powder, are uniformly sprinkling upon It in oil, and is stirred 5 to 8 minutes with five up times, when dense smoke emits most, uses slow boiling instead and continue stirring tanning 5 to 15 minutes, lotion Color and luster can be spare from fire when being in shiny black；

Step 6: it releases fire-toxin：Boiled plaster in step 5 is poured into the well water got ready, impregnates three to five days and changes water daily Once, it is spare；

Step 7: go dryness evil：The plaster soaked in step 6 is dried in the shade, is packed into terrine, is sealed with beeswax and fills mouth, embedment is shady and cool Cellar is put within 7 to 10th at dry 15, it is spare；

Step 8: unpacking：By in step 7 in terrine nature and flavor, smell, color and luster have reached requirement plaster take out separately storage, It is spare；

Step 9: stand medicine：Moschus 0.06g, borneol 0.2g, dragon's blood 30g will be added after plaster block water-bath fusing in step 8 Plaster is uniformly applied to cotton, i.e. usable on dogskin by fine medicinal material with bamboo chip after stirring evenly.

Embodiment three, Radix Angelicae Sinensis 35g, Caulis Spatholobi 55g, Radix Angelicae Pubescentis 35g, monkshood 70g, radix aconiti agrestis 70g, turpentine 35g, lycopodium calvatum 35g, Pawpaw 20g, lopseed 35g, ground bettle 35g, flying worm 35g, full worm 35g, rhizoma typhonii 20g, dragon's blood 35g, safflower 20g, peach kernel 25g, frankincense 40g, myrrh 40g, semen momordicae 35g.

Step 1: it impregnates：By above-mentioned weight proportion, first by Radix Angelicae Sinensis, Caulis Spatholobi, Radix Angelicae Pubescentis, monkshood, radix aconiti agrestis, turpentine, stretch muscle Grass, pawpaw, lopseed, ground bettle, flying worm, full worm, rhizoma typhonii, dragon's blood, safflower, peach kernel, frankincense, myrrh, semen momordicae are put into eight It is impregnated in jin sesame oil, it is spring and summer five days, seven days autumn and winter, spare；

Step 2: it refines：By soaked drug in step 1 and sesame oil with slow boiling tanning 4 it is small when, and have peach, mulberry, Chinese scholartree, willow, Until medicinal material is withered and yellow when floating over liquid level, the removal dregs of a decoction are filtered from fire for elm, five stirrings, spare；

Step 3: distillation：Filtered medicine oil in step 2 is inserted again in refining container, add in 9g, centipede 9g medicines more than blood Material, then refined one hour with slow boiling, then the filtering removal dregs of a decoction, spare；

Step 4: oil refining：Filtered medicine oil in step 3 is inserted in refining container, experienced medicine oil is endured to dropping into a bead with slow boiling Shape, it is spare；

Step 5: lower pellet：By the medicine oil in step 4, heating with high heat is lower red again, and three jin of red leads are worn into fine powder, are uniformly sprinkling upon It in oil, and is stirred 5 to 8 minutes with five up times, when dense smoke emits most, uses slow boiling instead and continue stirring tanning 5 to 15 minutes, lotion Color and luster can be spare from fire when being in shiny black；

Step 6: it releases fire-toxin：Boiled plaster in step 5 is poured into the well water got ready, impregnates three to five days and changes water daily Once, it is spare；

Step 7: go dryness evil：The plaster soaked in step 6 is dried in the shade, is packed into terrine, is sealed with beeswax and fills mouth, embedment is shady and cool Cellar is put within 7 to 10th at dry 15, it is spare；

Step 8: unpacking：By in step 7 in terrine nature and flavor, smell, color and luster have reached requirement plaster take out separately storage, It is spare；

Step 9: stand medicine：Moschus 0.01g, borneol 0.3g, dragon's blood 35g will be added after plaster block water-bath fusing in step 8 Plaster is uniformly applied to cotton, i.e. usable on dogskin by fine medicinal material with bamboo chip after stirring evenly.

Radix Angelicae Pubescentis, monkshood and radix aconiti agrestis are made into composite behaviour test respectively, by the way that three kinds of medicinal materials are done combination not of the same race, to patient Time from medication to analgesic is tested, and test result is as follows：

There are stronger mating reactions, in each combination, three kinds of medicines between Radix Angelicae Pubescentis, monkshood, radix aconiti agrestis three as can be seen from the above table Material is simultaneously using most short to the healing time of patient pain.

To show that Chinese medicine of the present invention makees traumatic injury, rheumathritis, caput femoris necrosis with good blood-activating analgetic With, by it is of the invention on the market it is common treatment traumatic injury, rheumathritis, caput femoris necrosis external used medicine medicine compare Experiment, specific steps and result are as follows：

1st, 300 are selected as test group and carries out system clinical observation, and selects medical history, the state of an illness, age, gender and treatment side The comparable Patients with 300 Cases of method as a control group, patient age, gender, course of disease of test group and control group etc. items basic document It is essentially identical, no significant difference（P ＞ 0.05）.

2nd, therapy：Test group is using paste made of the preparation method described in the specific embodiment of the invention two, often It once, 15 days courses for the treatment of.Control group selects common treatment traumatic injury, rheumathritis, caput femoris necrosis on the market External used medicine treated, observation the cycle be 15 days.

3rd, test group and control group are inspected periodically using identical inspection method, will be inspected periodically result and are carried out statistical Analysis.

The variation of the symptom eliminates number of days such as table 1 two groups of patient skin swelling, pain, extravasated blood

As it can be seen from table 1 the time that test group eliminates either since symptom is still treated always on number of days, all much Higher than control group, test group patient after 5 days the symptoms such as swelling, pain, extravasated blood can completely disappear, and control group swelling, pain, The symptom of extravasated blood is only needed except half.

Leucocyte, neutrophil leucocyte, erythrocyte sedimentation rate testing result before and after 2 two groups of the table course of therapy of patient two

The inspection knot of test group quantity of leucocyte, neutrophil leucocyte quantity, erythrocyte sedimentation rate after two course of therapy as can be seen from Table 2 Fruit is all substantially reduced, and reaches normal value, although and control group also decreases, reduce unobvious, and be not reaching to just Constant value.Illustrate that traumatic injury, rheumathritis, the Irritation Trial group patient caused by caput femoris necrosis have obtained very big change It is kind, check that recovered normal value, disease are controlled data, and control group patient does not improve a lot, to disease Therapeutic effect unobvious.

3 two groups of table patient two course of therapy result counts

Wherein：Total effective rate=cure rate+improvement rate

The treatment total effective rate that two groups of patients are compared by table 3 can be found that test group apparently higher than control group, thus illustrates, originally Invention Chinese medicine has good effect of dissolving stasis and relieving pain to traumatic injury, rheumathritis, caput femoris necrosis, can effectively improve and control The cure rate for the treatment of is worth promoting in clinical practice.

Above example is only to illustrate the technical solution of type of the present invention, rather than its limitations；Although with reference to foregoing implementation Type of the present invention is described in detail in example, it will be understood by those of ordinary skill in the art that：It still can be to foregoing each Technical solution recorded in embodiment modifies or carries out equivalent substitution to which part technical characteristic；And these are changed Or replace, the essence of appropriate technical solution is not made to depart from the spirit and scope of each embodiment technical solution of type of the present invention.

Claims (7)

1. a kind of blood-activating analgetic plaster, which is characterized in that the blood-activating analgetic plaster mainly by Radix Angelicae Sinensis, Caulis Spatholobi, Radix Angelicae Pubescentis, monkshood, radix aconiti agrestis, Turpentine, lycopodium calvatum, pawpaw, lopseed, ground bettle, flying worm, full worm, rhizoma typhonii, dragon's blood, safflower, peach kernel, frankincense, myrrh, Momordica cochinchiensis Son composition, by sorting, immersion, refinement, distillation, oil refining, it is lower it is red, release fire-toxin, dryness evil, unpacking, beach gone to be made.

2. blood-activating analgetic plaster according to claim 1, which is characterized in that the weight proportion of bulk pharmaceutical chemicals in the blood-activating analgetic plaster It is as follows：Radix Angelicae Sinensis 25-35g, Caulis Spatholobi 45-55g, Radix Angelicae Pubescentis 25-35g, monkshood 50-70g, radix aconiti agrestis 50-70g, turpentine 25-35g, muscle is stretched Careless 25-35g, pawpaw 10-20g, lopseed 25-35g, ground bettle 25-35g, flying worm 25-35g, full worm 25-35g, rhizoma typhonii 10- 20g, dragon's blood 25-35g, safflower 10-20g, peach kernel 15-25g, frankincense 30-40g, myrrh 30-40g, semen momordicae 25-35g.

3. blood-activating analgetic plaster according to claim 1, which is characterized in that the weight proportion of bulk pharmaceutical chemicals in the blood-activating analgetic plaster It is as follows：It is Radix Angelicae Sinensis 30g, Caulis Spatholobi 50g, Radix Angelicae Pubescentis 30g, monkshood 60g, radix aconiti agrestis 60g, turpentine 30g, lycopodium calvatum 30g, pawpaw 15g, deep Careless 30g, ground bettle 30g, flying worm 30g, full worm 30g, rhizoma typhonii 15g, dragon's blood 30g, safflower 15g, peach kernel 20g, frankincense 35g, do not have Medicine 35g, semen momordicae 30g.

4. according to claim 1-3 any one of them blood-activating analgetic plaster, which is characterized in that the blood-activating analgetic plaster is also added into Blood is remaining, centipede, Moschus, borneol.

5. blood-activating analgetic plaster according to claim 4, which is characterized in that the weight proportion of drug is such as in the blood-activating analgetic plaster Under：4-9g, centipede 3-9g, Moschus 0.03-0.1g, borneol 0.1-0.3g more than blood.

6. blood-activating analgetic plaster according to claim 5, which is characterized in that the weight proportion of drug is such as in the blood-activating analgetic plaster Under：6g, centipede 6g, Moschus 0.06g, borneol 0.2g more than blood.

7. blood-activating analgetic plaster according to claim 4, which is characterized in that the preparation method of the blood-activating analgetic plaster is as follows：

Step 1: it impregnates：By weight proportion of the present invention, first by Radix Angelicae Sinensis, Caulis Spatholobi, Radix Angelicae Pubescentis, monkshood, radix aconiti agrestis, turpentine, lycopodium calvatum, Pawpaw, lopseed, ground bettle, flying worm, full worm, rhizoma typhonii, dragon's blood, safflower, peach kernel, frankincense, myrrh, semen momordicae are put into sesame oil It impregnates, it is spring and summer five days, seven days autumn and winter, spare；

Step 2: it refines：By soaked drug in step 1 and sesame oil with slow boiling tanning 4 it is small when, and have peach, mulberry, Chinese scholartree, willow, Until medicinal material is withered and yellow when floating over liquid level, the removal dregs of a decoction are filtered from fire for elm, five stirrings, spare；

Step 3: distillation：Filtered medicine oil in step 2 to be inserted again in refining container, addition blood is remaining, centipede medicinal material, then It is refined one hour with slow boiling, then the filtering removal dregs of a decoction, spare；

Step 4: oil refining：Filtered medicine oil in step 3 is inserted in refining container, experienced medicine oil is endured to dropping into a bead with slow boiling Shape, it is spare；

Step 5: lower pellet：By the medicine oil in step 4, heating with high heat is lower red again, and red lead is worn into fine powder, is uniformly spread in the oil, And stirred 5 to 8 minutes with five up times, when dense smoke emits most, use slow boiling instead and continue stirring tanning 5 to 15 minutes, lotion color and luster In it is shiny black when can be spare from fire；

Step 6: it releases fire-toxin：Boiled plaster in step 5 is poured into the well water got ready, impregnates three to five days and changes water daily Once, it is spare；

Step 7: go dryness evil：The plaster soaked in step 6 is dried in the shade, is packed into terrine, is sealed with beeswax and fills mouth, embedment is shady and cool Cellar is put within 7 to 10th at dry 15, it is spare；

Step 8: unpacking：By in step 7 in terrine nature and flavor, smell, color and luster have reached requirement plaster take out separately storage, It is spare；

Step 9: stand medicine：The fine medicinal material stirring of Moschus, borneol, dragon's blood will be added after plaster block water-bath fusing in step 8 Plaster is uniformly applied to after uniformly with bamboo chip cotton, i.e. usable on dogskin.