CN108088723A - A kind of decanter type Thinprep pap test pelleter - Google Patents

A kind of decanter type Thinprep pap test pelleter Download PDF

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Publication number
CN108088723A
CN108088723A CN201810090319.6A CN201810090319A CN108088723A CN 108088723 A CN108088723 A CN 108088723A CN 201810090319 A CN201810090319 A CN 201810090319A CN 108088723 A CN108088723 A CN 108088723A
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Prior art keywords
axis
line slideway
group
axis line
tip
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CN201810090319.6A
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Chinese (zh)
Inventor
廖乘胜
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WUHAN HER MEDICAL TECHNOLOGY DEVELOPMENT Co Ltd
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WUHAN HER MEDICAL TECHNOLOGY DEVELOPMENT Co Ltd
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Priority to CN201810090319.6A priority Critical patent/CN108088723A/en
Publication of CN108088723A publication Critical patent/CN108088723A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • G01N2001/386Other diluting or mixing processes

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The present invention relates in cell pathology equipment technical field, and in particular to a kind of decanter type Thinprep pap test pelleter.Sample transfer function is merged into pelleter by the decanter type Thinprep pap test pelleter, realizes the integration and automation of liquid relief and film-making;The disposable syringe that cost is higher and waste is more serious is changed to low-cost pipette, reduces consumptive material use cost;For transfer sample it is easily chaotic the problem of, the pelleter of the present invention is equipped with orderly work top layout, it is designed using by component cloth, by group operation during work, all operations related with specimen fluids are carried out in group, there is no intersecting between group and group, the cross contamination brought by dropping liquid or maloperation is avoided.

Description

A kind of decanter type Thinprep pap test pelleter
Technical field
The present invention relates in cell pathology equipment technical field, and in particular to a kind of decanter type Thinprep pap test film-making Machine.
Background technology
Liquid-based cell sample manufacturing is the vital step of cervical cancer cell examination, is the follow-up basis guarantor for dyeing and diagnosing Barrier, only qualified smear could correctly reflect pathological state, and doctor is helped to make correct diagnosis.Therefore, film-making is cytology A particularly important ring in diagnostic method, it is necessary to the reasonable effective flaking method of design and device.
Existing cell chip preparing machine is mainly membrane type method pelleter, natural sedimentation pelleter and centrifugal settling method pelleter, Wherein membrane type method pelleter by membrane tube extract cell, though cell can thin layer be uniformly distributed, clean background, free from admixture, not It can all extract with diagnostic value cell.Cell is deposited to by centrifugation on thin slice by centrifugal settling method pelleter, carefully Born of the same parents measure abundance, but are automatically controlled due to that can not realize, cell accumulation, overlapping, cellular morphology deformation, background are unintelligible.Naturally it is heavy Drop legal system piece machine introduces cell separation and extraction technology and weeds out mucus and impurity in advance, can exclude in sample blood or mucus into Divide interference, the cell component with diagnostic significance is enriched with, finally utilize cell self gravitation effect natural subsidence film-making, keep The original form of cell, cell pyknosis or creeping phenomenon are less, and cell distribution is uniform, be comparatively ideal flaking method.
Existing precipitating type liquid based thinlayer cytology moviemaking system (LCT) include low speed horizontal centrifuge, sample transfer and Settle dyeing machine three parts, low speed horizontal centrifuge be used for centrifuge tube gradient centrifugation, accurately control centrifugal force and from The heart time;Sample processor groundwork is will to be added to gradient liquid upper strata after sample mixing at a slow speed, forms pre- layering;Film-making contaminates Sample dilutions mixing after the completion of secondary centrifuging is transferred to natural subsidence film-making in preparation bin and is automatically performed cell dye by color machine Color.
Concrete operations flow is that cytobrush brush head fractures after drawing materials to be retained in specimen bottle, after specimen fluids are vibrated mixing 8ml is taken to be slowly added to, in advance plus in the centrifugation Taper Pipe of good 4ml density gradient liquid, spend since density gradient is liquid-tight and be more than sample Liquid, the specimen fluids of addition, which float on, forms layering on Graded Density reagent, then will centrifugation Taper Pipe be put into centrifuge fully from The heart is twice.Cell is at layering interfaces after centrifuging for the first time, and mucus is located at upper strata, and mucus is sucked with vacuum pump.Second from Blood and other interference components are further separated after the heart, cell of the enrichment with diagnostic significance is put into vortex oscillator, makes afterwards Cell is obtained to suspend again.Finally by specimen preparation and dyeing, when film-making, has been kept using cell gravity natural subsidence, cellular morphology It is whole, and sick cell, since proportion is more than normal cell, sinking speed is very fast, therefore the preferential glass for being coated with cell adherence agent Piece captures.LCT pelleters can once be opened with film-making 48, take about 1 it is small when.From the point of view of production effect, cell is more concentrated, and distribution is more Uniformly, there is a small amount of overlapping but deformed without drawing, for cell without degradation degeneration, coloring is good, meets diagnosis requirement.Have benefited from unification Change, standardize, the processing routine of automation, specimen quality can be also consistent.But there are following Railway Projects for the flow:
1. consumptive material is more.Medical disposable material have specimen bottle, liquid relief syringe, centrifuge tube, 1ml liquid reliefs TIP pipe, preparation bin and Adhesiveness glass slide etc., wherein liquid relief syringe use cost highest, waste are serious;
2. needing to add gradient liquid to every centrifuge tube by hand, the degree of automation is inadequate;
3. sample needs to shift between devices, and needs each sample being put into correspondence position, easily chaotic;
4. liquid relief TIP pipes can only operate one by one during film-making, less efficient;
5. only four kinds of dye liquor species can be used, and conduit component not acid-alkali-corrosive-resisting, pap staining can only be done.
The content of the invention
For technical problem in the prior art, object of the present invention is to provide a kind of decanter type liquid-based thin layers Sample transfer function is merged into pelleter by cell chip preparing machine, realizes the integration and automation of liquid relief and film-making, greatly It improves work efficiency greatly.
The technical proposal of the invention is realized in this way:
A kind of decanter type Thinprep pap test pelleter, including left socle, right support, pedestal, workbench, three axis samplers Tool device and driving device;The workbench is arranged on pedestal;The left socle supports three axis sampling mechanical device left ends, right Stent supports three axis sampling mechanical device right ends, and left socle and right support make three axis sampling mechanical devices set on the table Portion;
Gradient liquid storehouse, buffer solution storehouse and several groups of pelletizers are set on the workbench, and every group of pelletizer includes suitable TIP pipes group, specimen bottle group, centrifuge tube group, adhesiveness glass slide group and the sedimentation preparation bin group of sequence arrangement, in every group of pelletizer TIP pipes, specimen bottle, centrifuge tube, adhesiveness glass slide are identical with sedimentation preparation bin number;
The three axis sampling mechanical device include planer-type truss, the multidimensional line slideway on planer-type truss and Mechanical arm assembly, the multidimensional line slideway include X-axis line slideway, Y-axis line slideway and Z axis line slideway, and Y-axis straight line is led Rail is mounted on two crossbeams of planer-type truss Y direction, and X-axis line slideway is arranged between two Y-axis line slideways, and It can be slided along Y-axis line slideway, Z axis line slideway is fixedly connected with the first sliding block that can be slided on X-axis line slideway;It is described Mechanical arm assembly includes several TIP pipe fittings and TIP pipe fitting fixed frames, the TIP pipe fittings fixed frame and Z axis line slideway It is slidably connected, the TIP pipe fittings are arranged on TIP pipe fitting fixed frames lower part, and the TIP pipe fittings connect plunger pump;
The kinetic control system for control three axis sampling mechanical devices (5) during film-making correct transfering reagent, It sample and mixing is carried out to sample breaks up operation, the kinetic control system connection driving device.
Further, the workbench further includes support plate and supporting rack, and support frame as described above is set on the supporting plate, described TIP pipes, specimen bottle, centrifuge tube, adhesiveness glass slide and sedimentation preparation bin in pelletizer are arranged on supporting rack.
Further, the mating dedicated TIP pipes in the gradient liquid storehouse and buffer solution storehouse.
Further, 4 groups of pelletizers are set on the workbench.
Further, the driving device includes X-axis servomotor, Y-axis servomotor and Z axis servomotor, the X-axis Servomotor connects X-axis line slideway, Y-axis servomotor connection Y-axis line slideway, and Z axis servomotor connection Z axis straight line is led Rail.
Further, the mechanical arm assembly, which further includes, unloads tube sheet and electromagnet lock core, and TIP pipe fittings, which run through, unloads tube sheet, And TIP pipe fittings is made to be flexibly connected with unloading tube sheet;The electromagnet lock core is arranged on Z axis line slideway.
Further, the plunger pump is multichannel plunger pump, and each passage connects a TIP pipe fitting.
Further, the multichannel plunger pump includes several cylinders and a linear stepping motor, Mei Yisuo A floating junction is set before stating cylinder;Each cylinder is driven simultaneously by the linear stepping motor.
Further, the pelleter further includes housing, and the housing is arranged on gradient liquid storehouse, the outside in buffer solution storehouse, Control panel and switch are set on housing, for the operation of control settlement formula Thinprep pap test pelleter.
Compared with prior art, the beneficial effects of the present invention are:
(1) sample transfer function is merged into film-making by a kind of decanter type Thinprep pap test pelleter disclosed by the invention In machine, the integration and automation of liquid relief and film-making are realized;
(2) disposable syringe that cost is higher and waste is more serious is changed to low-cost pipette, reduces consumption Material use cost:The present invention eliminates the higher liquid relief syringe of cost, uses the 10ml specification TIP pipettes of low cost instead, uses Multiple plunger pumps replace syringe piston function, plunger pump by tracheae and TIP pipes connection it is not direct contacted with liquid, prevent Cross contamination ensure that service life;TIP pipes can not only be used in liquid relief step, but also can be used for after shifting secondary centrifuging Cell, eliminate the TIP pipettes of another 1ml specification;
(3) for transfer sample it is easily chaotic the problem of, pelleter of the invention be equipped with orderly work top layout and A kind of special centrifuge tube transfer frame, is designed using by component cloth, and by group operation during work, all operations related with specimen fluids are all It is to be carried out in group, there is no intersecting between group and group, avoids the cross contamination brought by dropping liquid or maloperation;
(4) for the problem of sample efficiency is low is shifted, the present invention devises gantry truss-like three-dimensional machinery arm, has There is high efficiency and high stability, simple in structure, easy to maintain.
Description of the drawings
Fig. 1 is the general assembly drawing of the decanter type Thinprep pap test pelleter of the present invention;
Fig. 2 is the structure diagram of the decanter type Thinprep pap test film-making machine worktable of the present invention;
Fig. 3 is the structure diagram of the three axis sampling mechanical device of decanter type Thinprep pap test pelleter of the present invention;
Fig. 4 is the structure diagram of the decanter type Thinprep pap test pelleter multichannel plunger pump of the present invention.
In figure:1- left socles, 2- right supports, 3- pedestals, 4- workbench, 5 three axis sampling mechanical devices, 41-TIP pipes group, 42- specimen bottles group, 43- centrifuge tubes group, 44- sedimentation preparation bins group, 45- adhesiveness glass slides group, 46- support plates, 47- supports Frame, 48- gradient liquid storehouse, 49- buffer solutions storehouse, 51- planer-types truss, 52-X axis line slideway, 53-Y axis line slideway, 54-Z axis Line slideway, the first sliding blocks of 55-, 56- mechanical arm assemblies, 57-TIP pipe fittings, 58-TIP pipe fittings fixed frame, 59- unload tube sheet, 61- linear stepping motors, 62-T types screw, 63- floating junctions, 64- cylinders
Specific embodiment
It shows that example illustrates certain embodiments of the present invention, and should not be construed as the model of the limitation present invention It encloses.Present disclosure can be improved from material, method and reaction condition simultaneously, all these improvement should all It falls within the spirit and scope of the present invention.
Embodiment:
As shown in Figure 1, a kind of decanter type Thinprep pap test pelleter, including include left socle 1, right support 2, pedestal 3, Workbench 4, three axis sampling mechanical devices 5, driving device and kinetic control system;The workbench 4 is set on the base 3;Institute It states left socle 1 and supports three axis sampling mechanical devices, 5 left end, right support 2 supports three axis sampling mechanical devices, 5 right end, 1 He of left socle Right support 2 makes three axis sampling mechanical devices 5 be arranged on 4 top of workbench.
As shown in Fig. 2, workbench 4 includes support plate 46 and supporting rack 47, supporting rack 47 is arranged in support plate 46, this reality The workbench 4 for applying example is divided to for two row, each column two groups of pelletizers of setting.In the outermost of workbench 4, gradient liquid is arranged side by side Storehouse 48, buffer solution storehouse 49;Every group of pelletizer includes tactic TIP pipes group 41, specimen bottle group 42, centrifuge tube group 43, viscous Attached property glass slide group 45 and sedimentation preparation bin group 44, TIP pipes, specimen bottle, centrifuge tube, adhesiveness glass slide in every group of pelletizer It is identical with sedimentation preparation bin number, it is 6.TIP pipes, specimen bottle, centrifuge tube, adhesiveness glass slide in pelletizer and heavy Drop preparation bin is arranged on supporting rack 47.Centrifuge tube in the present embodiment is located on centrifuge tube shelf, the centrifuge tube shelf Slant setting and vertical placement two states are may be configured as, for the two kinds of operating modes selections of liquid relief and film-making.
Workbench is used to be designed by component cloth, and when work is also by a group operation, and each sample is to regard to individual TIP Pipe, all operations related with specimen fluids are carried out in group, there is no intersecting between group and group, are avoided because of dropping liquid or mistake Operate the cross contamination brought.Gradient liquid and buffer solution, which belong to, shares reagent, also needs to avoid cross contamination.The solution of use is It is managed for the special tip of its mating same specification, ensure to contact with reagent is all this special tip pipe.Buffer solution additive amount is less, The tip pipes of 10ml, which can meet, once adds four groups, and one group of special tip pipe is configured on buffer solution storehouse.And gradient liquid is every Group need to add 4ml, and the tip pipes of 10ml, which obviously cannot meet, once adds all groups, can be entered here using every group of tip pipes Sample be contaminated before neutral gear, be first used for adding gradient liquid, i.e., every group of TIP pipes first step operation is exactly from the absorption of gradient liquid storehouse 4ml reagents enter back into specimen fluids and carry out subsequent operation, so ensure that shared gradient liquid is not contaminated afterwards.
As shown in figure 3, three axis sampling mechanical devices 5 use planer-type truss structure, built by multidimensional line slideway, Its spatial movement realized with three orthogonal linear motions, have can high-speed cruising, installation and debugging facilitate etc. excellent Point can reach very high positional precision.Three axis sampling mechanical devices 5 specifically include planer-type truss 51, mounted on planer-type purlin Multidimensional line slideway and mechanical arm assembly 56 on frame, multidimensional line slideway include X-axis line slideway 52, Y-axis line slideway 53 With Z axis line slideway 54, Y-axis line slideway 53 is mounted on two crossbeams of planer-type truss 51Y direction of principal axis, and X-axis straight line is led Rail 52 is arranged between two Y-axis line slideways 53, and can be slided along Y-axis line slideway 53, Z axis line slideway 54 with can be in X The first sliding block 55 slided on axis line slideway 52 is fixedly connected;X-axis line slideway 52, Y-axis line slideway 53 and Z axis straight line are led Corresponding servomotor is all connected on rail 54, the correct transfering reagent of film-making flow and sample are pressed for driving manipulator component 56, And mixing is carried out to sample and the operations such as breaks up.Mechanical arm assembly 56 includes 6 and is managed with 41 corresponding TIP of TIP pipes group in workbench 4 Connector 57 and TIP pipe fittings fixed frame 58, TIP pipe fittings fixed frame 58 are slidably connected with Z axis line slideway 54, and 6 TIP pipes connect First 57 are arranged on 58 lower part of TIP pipe fittings fixed frame, the disposable loading in a manner that Z axis downlink is pressed into.Each TIP pipe fittings One passage of connecting multi-channel plunger pump.In order to facilitate loading and unload TIP pipe fittings, the dress of TIP pipe fittings fixed frame 58 One end of TIP pipe fittings installs one piece and unloads tube sheet 59, and TIP pipe fittings 57, which run through, to be unloaded tube sheet 59 and make TIP pipe fittings 57 and unload pipe Plate 59 is flexibly connected, and an electromagnet lock core is installed on Z axis line slideway 54, and electromagnet lock core, which hooks, during unloading unloads tube sheet, Support plate is unloaded when Z axis uplink to be relatively fixed, TIP pipes are extruded under the extruding for unloading support plate.
In the present embodiment, the effect of plungers pump plunger pump is to provide positive and negative air-pressure to TIP pipes, passes through volume displaced effect Liquid is drawn or discharges, as long as the liquid drawn is no more than the capacity of TIP pipes, liquid, which would not enter in pipeline, to be polluted. Required absorption amount of liquid is 0-8ml, therefore TIP tube capacity amounts select 10ml.Plunger pumpage is up to 15ml, more than TIP tube capacity amounts, Gas has subtle expansion or compression during because of work, need to consider surplus.Assembly of the plunger pump sets 6 parallel channels, each passage altogether Transtracheal connects a TIP pipe.Cylinder seal circle has self-lubricating function, can reduce abrasion and maintenance, lift-off seal and use Service life.6 cylinders 64 are driven by same linear stepping motor 61, and the exhaust that linear motion is converted to cylinder acts, directly The distance of line movement is exactly the size of capacity, and easy to control, precision is higher.To prevent multiple cylinder error in mounting position peace What row degree error band came interlocks stuck phenomenon when being synchronized with the movement, a floating junction 63 is added in before every cylinder, enables six cylinders synchronous suitable Smooth operation.
Decanter type Thinprep pap test pelleter in the present embodiment is also provided with housing 6, and housing 6 is arranged on gradient liquid storehouse 48th, the outside in buffer solution storehouse 49 sets control panel 7 and switch 8 on housing 6, for control settlement formula Thinprep pap test system The operation of piece machine.
Kinetic control system in the present embodiment correctly shifts for three axis sampling mechanical devices 5 of control during film-making It reagent, sample and mixing is carried out to sample breaks up operation, the kinetic control system connects driving device and plunger pump.
The operation principle of decanter type Thinprep pap test pelleter of the present invention is:1) operation of host computer reception user refers to Order, set workbench, three axis sampling mechanical devices and pump with the relevant running parameter of work order, and parameter monolithic will be made Machine control system;2) single-chip computer control system obtains sampling mechanical dress according to work in every parameter, film-making program, corresponding algorithm The actual motion trace information and the real work parameter of pump put, and actual motion trace information is sent to three axis sampling mechanicals Device;The real work parameter of pump is sent to plunger pump;3) three axis sampling mechanical devices receive actual motion trace information and refer to Order, plunger pump receive running parameter instruction, each carry out liquid relief, tableting operation according to according to instruction.
Liquid relief, tableting operation step are:
According to workflow, under the operation effect of three axis sampling mechanical devices, plunger pump controls TIP pipes from gradient first Liquid storehouse is drawn 4ml gradient liquid and is added in this group of centrifuge tube, and tip pipes enter specimen bottle mixing and break up cell and draw 8ml marks afterwards This liquid is transferred on tilted-putted centrifuge tube, and specimen fluids form pre- layering with gradient liquid after slowly having injected.Hereafter centrifuge tube It is transferred to centrifuge to be centrifuged twice, puts back to work top again after finishing, the difference is that centrifuge tube is put by inclination before It puts and makes into place vertically, tip pipes are again started up, and 1ml buffer solutions are first drawn out of buffer solution storehouse and add in mixing dilution in centrifuge tube, Then the cell liquid after absorption 0.5-1ml mixings is transferred to preparation bin and carries out sedimentation film-making.
Sample transfer function is merged into pelleter by a kind of decanter type Thinprep pap test pelleter disclosed by the invention In, realize the integration and automation of liquid relief and film-making;The disposable syringe that cost is higher and waste is more serious is changed to Low-cost pipette reduces consumptive material use cost;For the problem of sample is easily chaotic is shifted, pelleter of the invention is matched somebody with somebody Standby work top layout in order, is designed using by component cloth, by group operation, all operations related with specimen fluids during work All it is to be carried out in group, there is no intersecting between group and group, avoids the cross contamination brought by dropping liquid or maloperation;The present invention Gantry truss-like three-dimensional machinery arm is devised, with excellent with high efficiency and high stability, simple in structure, easy to maintain etc. Point.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto, Any one skilled in the art in the technical scope disclosed by the present invention, technique according to the invention scheme and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (9)

1. a kind of decanter type Thinprep pap test pelleter, which is characterized in that including including left socle (1), right support (2), bottom Seat (3), workbench (4), three axis sampling mechanical devices (5), driving device and kinetic control system;The workbench (4) is set On pedestal (3);The left socle (1) supports three axis sampling mechanical device (5) left ends, and right support (2) supports three axis samplers Tool device (5) right end, left socle (1) and right support (2) make three axis sampling mechanical devices (5) be arranged on workbench (4) top;
Gradient liquid storehouse (48), buffer solution storehouse (49) and several groups of pelletizers, every group of pelletizer are set on the workbench (4) Including tactic TIP pipes group (41), specimen bottle group (42), centrifuge tube group (43), adhesiveness glass slide group (45) and sedimentation Preparation bin group (44), TIP pipes, specimen bottle, centrifuge tube, adhesiveness glass slide and sedimentation preparation bin number phase in every group of pelletizer Together;
The three axis sampling mechanical device (5) includes planer-type truss (51), the multidimensional straight line on planer-type truss is led Rail and mechanical arm assembly (56), it is straight that the multidimensional line slideway includes X-axis line slideway (52), Y-axis line slideway (53) and Z axis Line guide rail (54), Y-axis line slideway (53) are mounted on two crossbeams of planer-type truss (51) Y direction, X-axis line slideway (52) be arranged between two Y-axis line slideways (53), and can be slided along Y-axis line slideway (53), Z axis line slideway (54) with The first sliding block (55) that can be slided on X-axis line slideway (52) is fixedly connected;The mechanical arm assembly (56) includes several TIP Pipe fitting (57) and TIP pipe fittings fixed frame (58), the TIP pipe fittings fixed frame (58) are slided with Z axis line slideway (54) Connection, the TIP pipe fittings (57) are arranged on TIP pipe fittings fixed frame (58) lower part, TIP pipe fittings (57) connection plunger pump;
The kinetic control system is for control three axis sampling mechanical devices (5) correct transfering reagent, sample during film-making Operation is broken up with mixing is carried out to sample, the kinetic control system connects driving device.
A kind of 2. decanter type Thinprep pap test pelleter according to claim 1, which is characterized in that the workbench (4) support plate (46) and supporting rack (47) are further included, support frame as described above (47) is arranged in support plate (46), the pelletizer In TIP pipes, specimen bottle, centrifuge tube, adhesiveness glass slide and sedimentation preparation bin be arranged on supporting rack (47).
A kind of 3. decanter type Thinprep pap test pelleter according to claim 1, which is characterized in that the gradient liquid storehouse (48) managed with buffer solution storehouse (49) mating dedicated TIP.
4. a kind of decanter type Thinprep pap test pelleter according to claim 1, which is characterized in that on the workbench 4 groups of pelletizers are set.
A kind of 5. decanter type Thinprep pap test pelleter according to claim 1, which is characterized in that the driving device Including X-axis servomotor, Y-axis servomotor and Z axis servomotor, the X-axis servomotor connection X-axis line slideway (52), Y Axis servomotor connection Y-axis line slideway (53), Z axis servomotor connection Z axis line slideway (54).
A kind of 6. decanter type Thinprep pap test pelleter according to claim 1, which is characterized in that the manipulator group Part (56), which further includes, unloads tube sheet (59) and electromagnet lock core, and TIP pipe fittings (57), which run through, unloads tube sheet (59), and makes TIP pipe fittings (57) it is flexibly connected with unloading tube sheet (59);The electromagnet lock core is arranged on Z axis line slideway (54).
7. a kind of decanter type Thinprep pap test pelleter according to claim 1, which is characterized in that the plunger pump is Multichannel plunger pump, each passage connect a TIP pipe fitting.
A kind of 8. decanter type Thinprep pap test pelleter according to claim 6, which is characterized in that the multi-channel column Plug pump includes several cylinders (64) and a linear stepping motor (61), and a floating junction is set before each cylinder (63);Each cylinder is driven simultaneously by the linear stepping motor (61).
9. a kind of decanter type Thinprep pap test pelleter according to claim 1, which is characterized in that the pelleter is also Including housing (6), the housing (6) is arranged on gradient liquid storehouse (48), the outside of buffer solution storehouse (49), and control is set on housing (6) Panel (7) processed and switch (8), for the operation of control settlement formula Thinprep pap test pelleter.
CN201810090319.6A 2018-01-30 2018-01-30 A kind of decanter type Thinprep pap test pelleter Pending CN108088723A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108613860A (en) * 2018-07-27 2018-10-02 上海皓信生物科技有限公司 Liquid-based pelleter
CN109297796A (en) * 2018-12-19 2019-02-01 孝感市森茂激光数控设备有限公司 A kind of sampling of automatic sedimentation pelleter and dye liquor injection device and method
CN109540601A (en) * 2018-12-19 2019-03-29 孝感市森茂激光数控设备有限公司 A kind of suction nozzle buffer mechanism of automatic sedimentation pelleter
CN111238890A (en) * 2020-01-16 2020-06-05 江西业力医疗器械有限公司 Detection method for liquid-based fungi by using liquid-based flaking technology based on centrifugation method
CN113075006A (en) * 2021-03-19 2021-07-06 深圳市鹏一医疗仪器有限公司 Drop dyeing and piece making dyeing all-in-one machine capable of achieving direct wet sealing

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