CN108042642A - Pharmaceutical composition of oedema and preparation method thereof is gone in a kind of gynemetrics's postpartum anti-inflammatory - Google Patents

Pharmaceutical composition of oedema and preparation method thereof is gone in a kind of gynemetrics's postpartum anti-inflammatory Download PDF

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CN108042642A
CN108042642A CN201810046594.8A CN201810046594A CN108042642A CN 108042642 A CN108042642 A CN 108042642A CN 201810046594 A CN201810046594 A CN 201810046594A CN 108042642 A CN108042642 A CN 108042642A
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parts
gynemetrics
inflammatory
gone
oedema
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孙桂霞
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/355—Lonicera (honeysuckle)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention discloses the pharmaceutical composition that oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory, include the raw material of following parts by weight：30 50 parts of the coptis, 20 40 parts of Sculellaria barbata, 12 40 parts of Inula britannica chinensis, 10 30 parts of bitter citrus immature flower, 14 34 parts of sunset abelmoschus flower, 4 14 parts of thick stick perfume (or spice) rattan, 1 10 parts of cloud Siberian cocklebur skin, 3 12 parts of kuh-seng, 39 parts of Rhizoma Atractylodis Macrocephalae preparata, 28 parts of Schisandra chinensis, 5 15 parts of Cortex Phellodendri, 10 32 parts of honeysuckle, 27 parts of the root of Dahurain angelica, 18 parts of Radix Glycyrrhizae, 1 10 parts of vitamin E；The present invention proposes the preparation method that edema drugs composition is removed in a kind of gynemetrics's postpartum anti-inflammatory, comprises the following steps：S1 weighs the coptis, Sculellaria barbata, Inula britannica chinensis, bitter citrus immature flower, sunset abelmoschus flower, thick stick perfume (or spice) rattan, Yun Lingpi, kuh-seng according to deal proportioning, is dried after above-mentioned raw materials are cleaned.The pharmaceutical composition of the present invention can effectively treat cyesedema, prevention postpartum vaginal inflammation, pelvic infecton, evident in efficacy, and women can more effectively be helped to recover body, while the present invention is without any side effects, and treatment cost is low, is suitble to promote.

Description

Pharmaceutical composition of oedema and preparation method thereof is gone in a kind of gynemetrics's postpartum anti-inflammatory
Technical field
The present invention relates to the pharmaceutical compositions that gynemetrics's technical field more particularly to a kind of gynemetrics's postpartum anti-inflammatory go oedema And preparation method thereof.
Background technology
After forepart pregnant women, the positions such as limbs appearance occur edema, the easy inflammation in vagina position, easily occur cyesedema, A series of diseases such as postpartum vaginal inflammation, pelvic infecton.Clinical manifestation is pudendal pruritus swelling and pain, limbs of patient oedema, the edema of the face, is lacked The lazy speech of gas, loss of appetite, pain in the back, big loose stool is thin, tongue nature is light, and tongue is white, and slippery is powerless etc..The traditional Chinese medical science is considered that postpartum spleen, kidney are double empty It is caused；In addition nausea stops up resistance, mechanism of qi blocks up, water-damp not being transformed also results in swelling.In the prior art, treat with medicinal herbs and treat cyesedema side Agent is more, and curative effect is imprecise.
There is fungi autoeciousness in women's postpartum there are about 30% pregnant woman's intravaginal, is primarily due to gestational period vaginal epithelial cell sugar Former content increases, and vagina acidity is more than 4, and the renal glucose threshold of pregnant woman reduces in addition, normal nutritious property glycosuria, sugared content liter in urine Height promotes the growth and breeding of Candida albicans, triggers inflammation.Pregnant woman is in gestation, particularly in pregnant middle and advanced stage, It is common pregnancy complication to suffer from monilial vaginitis, and incidence is about 15%, and western medicine treatment effect is bad at present, and pair is made With larger, and allergy and drug resistance are easily generated, therefore it is proposed that the pharmaceutical composition of oedema is removed in a kind of gynemetrics's postpartum anti-inflammatory Object and preparation method thereof.
The content of the invention
Technical problems based on background technology, the present invention propose the drug that oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory Composition and preparation method thereof.
The pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory proposed by the present invention, includes the original of following parts by weight Material：30-50 parts of the coptis, 20-40 parts of Sculellaria barbata, 12-40 parts of Inula britannica chinensis, 10-30 parts of bitter citrus immature flower, 14-34 parts of sunset abelmoschus flower, thick stick are fragrant 4-14 parts of rattan, 1-10 parts of cloud Siberian cocklebur skin, 3-12 parts of kuh-seng, 3-9 parts of Rhizoma Atractylodis Macrocephalae preparata, 2-8 parts of Schisandra chinensis, 5-15 parts of Cortex Phellodendri, honeysuckle 10- 32 parts, 2-7 parts of the root of Dahurain angelica, 1-8 parts of Radix Glycyrrhizae, 1-10 parts of vitamin E.
Preferably, the raw material of following parts by weight is included：35-45 parts of the coptis, 25-35 parts of Sculellaria barbata, 17-35 parts of Inula britannica chinensis, 15-25 parts of bitter citrus immature flower, 19-29 parts of sunset abelmoschus flower, 6-12 parts of thick stick perfume (or spice) rattan, 3-8 parts of cloud Siberian cocklebur skin, 5-10 parts of kuh-seng, Rhizoma Atractylodis Macrocephalae preparata 5-7 Part, 3-7 parts of Schisandra chinensis, 7-13 parts of Cortex Phellodendri, 15-25 parts of honeysuckle, 3-6 parts of the root of Dahurain angelica, 2-7 parts of Radix Glycyrrhizae, 3-7 parts of vitamin E.
Preferably, the raw material of following parts by weight is included：40 parts of the coptis, 30 parts of Sculellaria barbata, 25 parts of Inula britannica chinensis, bitter citrus immature flower 20 Part, 25 parts of sunset abelmoschus flower, 9 parts of thick stick perfume (or spice) rattan, 5 parts of cloud Siberian cocklebur skin, 7 parts of kuh-seng, 6 parts of Rhizoma Atractylodis Macrocephalae preparata, 5 parts of Schisandra chinensis, 10 parts of Cortex Phellodendri, gold and silver Spend 20 parts, 4 parts of the root of Dahurain angelica, 4 parts of Radix Glycyrrhizae, 5 parts of vitamin E.
Preferably, the coptis, Sculellaria barbata, the weight ratio of Inula britannica chinensis are 35-45：25-35：17-35.
Preferably, the bitter citrus immature flower, sunset abelmoschus flower, the weight ratio of thick stick perfume (or spice) rattan are 15-25：19-29：6-12.
Preferably, the cloud Siberian cocklebur skin, kuh-seng, the weight ratio of Rhizoma Atractylodis Macrocephalae preparata are 3-8：5-10：5-7.
The present invention proposes the preparation method that edema drugs composition is removed in a kind of gynemetrics's postpartum anti-inflammatory, including following step Suddenly：
S1 weighs the coptis, Sculellaria barbata, Inula britannica chinensis, bitter citrus immature flower, sunset abelmoschus flower, thick stick perfume (or spice) rattan, Yun Lingpi, kuh-seng according to deal proportioning, It is dried after above-mentioned raw materials are cleaned, passes sequentially through pulverizer and crush, the mesh number of crushing is 200-300 mesh；
S2, the raw material after S1 is crushed are sequentially placed into cooker, are put into the 8-12 times of water measured, first big fire continuous heating 1-2h, Small fire continuous heating 30-50min again, obtains mixed liquor A；
S3 weighs Rhizoma Atractylodis Macrocephalae preparata, Schisandra chinensis, Cortex Phellodendri, honeysuckle, the root of Dahurain angelica, Radix Glycyrrhizae according to deal proportioning, is dried after cleaning, will be above-mentioned Raw material after drying is crushed by pulverizer, and the mesh number of crushing is 150-250 mesh, and the above-mentioned raw materials after crushing are blended in one It rises and obtains mixture B；
S4 adds in mixture B in mixed liquor A, adds in the 4-8 times of water measured, and continues small fire heating 3-4h, thick paste is obtained after concentration C；
S5 adds vitamin E into thick paste C, stirs and can obtain the medicine that oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory Compositions.
Preferably, described pharmaceutical composition is capsule or dripping pill.
In the present invention, the coptis has the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating.Sun plant all herbal medicine has clearing heat and detoxicating, living The functions such as blood and dissolving stasis, swelling and pain relieving, anticancer.Cold in nature sour, herb is containing ingredients such as multivitamin, trace element and amino acid. Inula britannica chinensis has immunological liver injury protective effect, and chemical composition gaillardin has antitumaous effect.Bitter citrus immature flower is used for chest and abdomen Bored distending pain, accumulation of food in the stomach and intes tine due to indigestion, phlegm and retained fluid, rectal prolapse, soothing the liver and stomach, qi-regulating.Sunset abelmoschus flower inducing diuresis for treating strangurtia；Promoting blood circulation；Hemostasis；Subdhing swelling and detoxicating. The effect of thick stick perfume (or spice) rattan has dispelling wind and eliminating dampness, promoting blood circulation and removing obstruction in channels, removing toxicity for detumescence, expelling insect and relieving itching.Cloud Siberian cocklebur skin cures mainly oedema general edema.This is sent out Bright ingredient is prepared according to certain method, is interacted between each ingredient, takes the pharmaceutical composition of the present invention, can be effective Treatment cyesedema, prevention postpartum vaginal is scorching, pelvic infecton, evident in efficacy, pay attention to low salt diet in daily life, and lie in bed Rest, more high fine foods of intake, keeps the skin wet, women can more effectively be helped to recover body, while the present invention is without any poison Side effect, treatment cost is low, is suitble to promote.
Specific embodiment
The present invention is made with reference to specific embodiment further to explain.
Embodiment one
The pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory proposed by the present invention, includes the raw material of following parts by weight：It is yellow 30 parts of company, 20 parts of Sculellaria barbata, 12 parts of Inula britannica chinensis, 10 parts of bitter citrus immature flower, 14 parts of sunset abelmoschus flower, 4 parts of thick stick perfume (or spice) rattan, 1 part of cloud Siberian cocklebur skin, kuh-seng 3 parts, 3 parts of Rhizoma Atractylodis Macrocephalae preparata, 2 parts of Schisandra chinensis, 5 parts of Cortex Phellodendri, 10 parts of honeysuckle, 2 parts of the root of Dahurain angelica, 1 part of Radix Glycyrrhizae, 1 part of vitamin E.
The present invention proposes the preparation method that edema drugs composition is removed in a kind of gynemetrics's postpartum anti-inflammatory, including following step Suddenly：
S1 weighs the coptis, Sculellaria barbata, Inula britannica chinensis, bitter citrus immature flower, sunset abelmoschus flower, thick stick perfume (or spice) rattan, Yun Lingpi, kuh-seng according to deal proportioning, It is dried after above-mentioned raw materials are cleaned, passes sequentially through pulverizer and crush, the mesh number of crushing is 200 mesh；
S2, the raw material after S1 is crushed are sequentially placed into cooker, are put into the water of 8 times of amounts, first big fire continuous heating 1h, then small fire Continuous heating 30min, obtains mixed liquor A；
S3 weighs Rhizoma Atractylodis Macrocephalae preparata, Schisandra chinensis, Cortex Phellodendri, honeysuckle, the root of Dahurain angelica, Radix Glycyrrhizae according to deal proportioning, is dried after cleaning, will be above-mentioned Raw material after drying is crushed by pulverizer, and the mesh number of crushing is 150 mesh, and the above-mentioned raw materials after crushing are mixed To mixture B；
S4 adds in mixture B in mixed liquor A, adds in the water of 4 times of amounts, continues small fire heating 3h, thick paste C is obtained after concentration；
S5 adds vitamin E into thick paste C, stirs and can obtain the medicine that oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory Compositions.
Embodiment two
The pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory proposed by the present invention, includes the raw material of following parts by weight：It is yellow 35 parts of company, 25 parts of Sculellaria barbata, 17 parts of Inula britannica chinensis, 15 parts of bitter citrus immature flower, 19 parts of sunset abelmoschus flower, 6 parts of thick stick perfume (or spice) rattan, 3 parts of cloud Siberian cocklebur skin, kuh-seng 5 parts, 5 parts of Rhizoma Atractylodis Macrocephalae preparata, 3 parts of Schisandra chinensis, 7 parts of Cortex Phellodendri, 15 parts of honeysuckle, 3 parts of the root of Dahurain angelica, 2 parts of Radix Glycyrrhizae, 3 parts of vitamin E.
The present invention proposes the preparation method that edema drugs composition is removed in a kind of gynemetrics's postpartum anti-inflammatory, including following step Suddenly：
S1 weighs the coptis, Sculellaria barbata, Inula britannica chinensis, bitter citrus immature flower, sunset abelmoschus flower, thick stick perfume (or spice) rattan, Yun Lingpi, kuh-seng according to deal proportioning, It is dried after above-mentioned raw materials are cleaned, passes sequentially through pulverizer and crush, the mesh number of crushing is 225 mesh；
S2, the raw material after S1 is crushed are sequentially placed into cooker, be put into 9 times amount water, first big fire continuous heating 1.25h, then Small fire continuous heating 35min, obtains mixed liquor A；
S3 weighs Rhizoma Atractylodis Macrocephalae preparata, Schisandra chinensis, Cortex Phellodendri, honeysuckle, the root of Dahurain angelica, Radix Glycyrrhizae according to deal proportioning, is dried after cleaning, will be above-mentioned Raw material after drying is crushed by pulverizer, and the mesh number of crushing is 175 mesh, and the above-mentioned raw materials after crushing are mixed To mixture B；
S4 adds in mixture B in mixed liquor A, adds in the water of 5 times of amounts, continues small fire heating 3.25h, thick paste is obtained after concentration C；
S5 adds vitamin E into thick paste C, stirs and can obtain the medicine that oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory Compositions.
Embodiment three
The pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory proposed by the present invention, includes the raw material of following parts by weight：It is yellow 40 parts of company, 30 parts of Sculellaria barbata, 25 parts of Inula britannica chinensis, 20 parts of bitter citrus immature flower, 25 parts of sunset abelmoschus flower, 9 parts of thick stick perfume (or spice) rattan, 5 parts of cloud Siberian cocklebur skin, kuh-seng 7 parts, 6 parts of Rhizoma Atractylodis Macrocephalae preparata, 5 parts of Schisandra chinensis, 10 parts of Cortex Phellodendri, 20 parts of honeysuckle, 4 parts of the root of Dahurain angelica, 4 parts of Radix Glycyrrhizae, 5 parts of vitamin E.
The present invention proposes the preparation method that edema drugs composition is removed in a kind of gynemetrics's postpartum anti-inflammatory, including following step Suddenly：
S1 weighs the coptis, Sculellaria barbata, Inula britannica chinensis, bitter citrus immature flower, sunset abelmoschus flower, thick stick perfume (or spice) rattan, Yun Lingpi, kuh-seng according to deal proportioning, It is dried after above-mentioned raw materials are cleaned, passes sequentially through pulverizer and crush, the mesh number of crushing is 250 mesh；
S2, the raw material after S1 is crushed are sequentially placed into cooker, be put into 10 times amount water, first big fire continuous heating 1.5h, then Small fire continuous heating 40min, obtains mixed liquor A；
S3 weighs Rhizoma Atractylodis Macrocephalae preparata, Schisandra chinensis, Cortex Phellodendri, honeysuckle, the root of Dahurain angelica, Radix Glycyrrhizae according to deal proportioning, is dried after cleaning, will be above-mentioned Raw material after drying is crushed by pulverizer, and the mesh number of crushing is 200 mesh, and the above-mentioned raw materials after crushing are mixed To mixture B；
S4 adds in mixture B in mixed liquor A, adds in the water of 6 times of amounts, continues small fire heating 3.5h, thick paste C is obtained after concentration；
S5 adds vitamin E into thick paste C, stirs and can obtain the medicine that oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory Compositions.
Example IV
The pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory proposed by the present invention, includes the raw material of following parts by weight：It is yellow 45 parts of company, 35 parts of Sculellaria barbata, 35 parts of Inula britannica chinensis, 25 parts of bitter citrus immature flower, 29 parts of sunset abelmoschus flower, 12 parts of thick stick perfume (or spice) rattan, 8 parts of cloud Siberian cocklebur skin, hardship 10 parts of ginseng, 7 parts of Rhizoma Atractylodis Macrocephalae preparata, 7 parts of Schisandra chinensis, 13 parts of Cortex Phellodendri, 25 parts of honeysuckle, 6 parts of the root of Dahurain angelica, 7 parts of Radix Glycyrrhizae, 7 parts of vitamin E.
The present invention proposes the preparation method that edema drugs composition is removed in a kind of gynemetrics's postpartum anti-inflammatory, including following step Suddenly：
S1 weighs the coptis, Sculellaria barbata, Inula britannica chinensis, bitter citrus immature flower, sunset abelmoschus flower, thick stick perfume (or spice) rattan, Yun Lingpi, kuh-seng according to deal proportioning, It is dried after above-mentioned raw materials are cleaned, passes sequentially through pulverizer and crush, the mesh number of crushing is 275 mesh；
S2, the raw material after S1 is crushed are sequentially placed into cooker, be put into 11 times amount water, first big fire continuous heating 1.75h, then Small fire continuous heating 45min, obtains mixed liquor A；
S3 weighs Rhizoma Atractylodis Macrocephalae preparata, Schisandra chinensis, Cortex Phellodendri, honeysuckle, the root of Dahurain angelica, Radix Glycyrrhizae according to deal proportioning, is dried after cleaning, will be above-mentioned Raw material after drying is crushed by pulverizer, and the mesh number of crushing is 225 mesh, and the above-mentioned raw materials after crushing are mixed To mixture B；
S4 adds in mixture B in mixed liquor A, adds in the water of 7 times of amounts, continues small fire heating 3.75h, thick paste is obtained after concentration C；
S5 adds vitamin E into thick paste C, stirs and can obtain the medicine that oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory Compositions.
Embodiment five
The pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory proposed by the present invention, includes the raw material of following parts by weight：It is yellow 50 parts of company, 40 parts of Sculellaria barbata, 40 parts of Inula britannica chinensis, 30 parts of bitter citrus immature flower, 34 parts of sunset abelmoschus flower, 14 parts of thick stick perfume (or spice) rattan, 10 parts of cloud Siberian cocklebur skin, hardship 12 parts of ginseng, 9 parts of Rhizoma Atractylodis Macrocephalae preparata, 8 parts of Schisandra chinensis, 15 parts of Cortex Phellodendri, 32 parts of honeysuckle, 7 parts of the root of Dahurain angelica, 8 parts of Radix Glycyrrhizae, 10 parts of vitamin E.
The present invention proposes the preparation method that edema drugs composition is removed in a kind of gynemetrics's postpartum anti-inflammatory, including following step Suddenly：
S1 weighs the coptis, Sculellaria barbata, Inula britannica chinensis, bitter citrus immature flower, sunset abelmoschus flower, thick stick perfume (or spice) rattan, Yun Lingpi, kuh-seng according to deal proportioning, It is dried after above-mentioned raw materials are cleaned, passes sequentially through pulverizer and crush, the mesh number of crushing is 300 mesh；
S2, the raw material after S1 is crushed are sequentially placed into cooker, are put into the water of 12 times of amounts, first big fire continuous heating 2h, then small Fiery continuous heating 50min, obtains mixed liquor A；
S3 weighs Rhizoma Atractylodis Macrocephalae preparata, Schisandra chinensis, Cortex Phellodendri, honeysuckle, the root of Dahurain angelica, Radix Glycyrrhizae according to deal proportioning, is dried after cleaning, will be above-mentioned Raw material after drying is crushed by pulverizer, and the mesh number of crushing is 250 mesh, and the above-mentioned raw materials after crushing are mixed To mixture B；
S4 adds in mixture B in mixed liquor A, adds in the water of 8 times of amounts, continues small fire heating 4h, thick paste C is obtained after concentration；
S5 adds vitamin E into thick paste C, stirs and can obtain the medicine that oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory Compositions.
In clinical treatment, 50 patients with inflammation and oedema are chosen, are divided into control group and experimental group, experimental group uses The pharmaceutical composition of embodiment three in the present invention, control group use western medicine：
1st day 10th day 20th day
Experimental group It is red and swollen using preceding private parts, there is inflammation, and have oedema, after use slightly Shade light feeling of pain Symptom is substantially reduced Symptom disappears, and has no adverse reaction
Control group It is red and swollen using preceding private parts, there is inflammation, and have oedema, after use slightly Shade light feeling of pain Feeling of pain mitigates, but symptom remains unchanged In the presence of Substantially vulva sore, burning heat sensation are alleviated, but It does not fully recover
The present invention can with help women recover body, treat oedema and anti-inflammatory, it is better to be aided with point massage, acupoint selection： Zusanli, Sanyinjiao, Yinlingquan, even reinforcing-reducing method gimmick also can smoke moxibustion at these acupuncture points with moxa stick.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto, Any one skilled in the art in the technical scope disclosed by the present invention, technique according to the invention scheme and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (8)

1. the pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory, which is characterized in that includes the raw material of following parts by weight：It is yellow 30-50 parts of company, 20-40 parts of Sculellaria barbata, 12-40 parts of Inula britannica chinensis, 10-30 parts of bitter citrus immature flower, 14-34 parts of sunset abelmoschus flower, thick stick perfume (or spice) rattan 4- 14 parts, 1-10 parts of cloud Siberian cocklebur skin, 3-12 parts of kuh-seng, 3-9 parts of Rhizoma Atractylodis Macrocephalae preparata, 2-8 parts of Schisandra chinensis, 5-15 parts of Cortex Phellodendri, honeysuckle 10-32 Part, 2-7 parts of the root of Dahurain angelica, 1-8 parts of Radix Glycyrrhizae, 1-10 parts of vitamin E.
2. the pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory according to claim 1, which is characterized in that including The raw material of following parts by weight：35-45 parts of the coptis, 25-35 parts of Sculellaria barbata, 17-35 parts of Inula britannica chinensis, 15-25 parts of bitter citrus immature flower, sunset abelmoschus root 19-29 parts of flower, 6-12 parts of thick stick perfume (or spice) rattan, 3-8 parts of cloud Siberian cocklebur skin, 5-10 parts of kuh-seng, 5-7 parts of Rhizoma Atractylodis Macrocephalae preparata, 3-7 parts of Schisandra chinensis, Cortex Phellodendri 7- 13 parts, 15-25 parts of honeysuckle, 3-6 parts of the root of Dahurain angelica, 2-7 parts of Radix Glycyrrhizae, 3-7 parts of vitamin E.
3. the pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory according to claim 1, which is characterized in that including The raw material of following parts by weight：40 parts of the coptis, 30 parts of Sculellaria barbata, 25 parts of Inula britannica chinensis, 20 parts of bitter citrus immature flower, 25 parts of sunset abelmoschus flower, thick stick are fragrant 9 parts of rattan, 5 parts of cloud Siberian cocklebur skin, 7 parts of kuh-seng, 6 parts of Rhizoma Atractylodis Macrocephalae preparata, 5 parts of Schisandra chinensis, 10 parts of Cortex Phellodendri, 20 parts of honeysuckle, 4 parts of the root of Dahurain angelica, Radix Glycyrrhizae 4 Part, 5 parts of vitamin E.
4. the pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory according to claim 1, which is characterized in that described The coptis, Sculellaria barbata, the weight ratio of Inula britannica chinensis are 35-45：25-35：17-35.
5. the pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory according to claim 1, which is characterized in that described Bitter citrus immature flower, sunset abelmoschus flower, the weight ratio of thick stick perfume (or spice) rattan are 15-25：19-29：6-12.
6. the pharmaceutical composition of oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory according to claim 1, which is characterized in that described Cloud Siberian cocklebur skin, kuh-seng, the weight ratio of Rhizoma Atractylodis Macrocephalae preparata are 3-8：5-10：5-7.
7. the preparation method of edema drugs composition is gone in a kind of gynemetrics's postpartum anti-inflammatory, which is characterized in that is comprised the following steps：
S1 weighs the coptis, Sculellaria barbata, Inula britannica chinensis, bitter citrus immature flower, sunset abelmoschus flower, thick stick perfume (or spice) rattan, Yun Lingpi, kuh-seng according to deal proportioning, It is dried after above-mentioned raw materials are cleaned, passes sequentially through pulverizer and crush, the mesh number of crushing is 200-300 mesh；
S2, the raw material after S1 is crushed are sequentially placed into cooker, are put into the 8-12 times of water measured, first big fire continuous heating 1-2h, Small fire continuous heating 30-50min again, obtains mixed liquor A；
S3 weighs Rhizoma Atractylodis Macrocephalae preparata, Schisandra chinensis, Cortex Phellodendri, honeysuckle, the root of Dahurain angelica, Radix Glycyrrhizae according to deal proportioning, is dried after cleaning, will be above-mentioned Raw material after drying is crushed by pulverizer, and the mesh number of crushing is 150-250 mesh, and the above-mentioned raw materials after crushing are blended in one It rises and obtains mixture B；
S4 adds in mixture B in mixed liquor A, adds in the 4-8 times of water measured, and continues small fire heating 3-4h, thick paste is obtained after concentration C；
S5 adds vitamin E into thick paste C, stirs and can obtain the medicine that oedema is gone in a kind of gynemetrics's postpartum anti-inflammatory Compositions.
8. the preparation method of edema drugs composition, feature are gone in a kind of gynemetrics's postpartum anti-inflammatory according to claim 1 It is, described pharmaceutical composition is capsule or dripping pill.
CN201810046594.8A 2018-01-18 2018-01-18 Pharmaceutical composition of oedema and preparation method thereof is gone in a kind of gynemetrics's postpartum anti-inflammatory Pending CN108042642A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108542955A (en) * 2018-05-29 2018-09-18 王芝秀 A kind of special anti-inflammatory medicine of postnatal care and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105434920A (en) * 2015-12-07 2016-03-30 张海燕 Postpartum antiphlogistic and edema-eliminating pharmaceutical composition for gynaecology and obstetrics and preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105434920A (en) * 2015-12-07 2016-03-30 张海燕 Postpartum antiphlogistic and edema-eliminating pharmaceutical composition for gynaecology and obstetrics and preparation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李保真；等: "广西壮族民间药用植物的初步研究(七)", 《广西医学》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108542955A (en) * 2018-05-29 2018-09-18 王芝秀 A kind of special anti-inflammatory medicine of postnatal care and preparation method thereof

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Application publication date: 20180518