CN107982481A - A kind of pill medicine for treating gout and preparation method thereof - Google Patents

A kind of pill medicine for treating gout and preparation method thereof Download PDF

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Publication number
CN107982481A
CN107982481A CN201711130067.7A CN201711130067A CN107982481A CN 107982481 A CN107982481 A CN 107982481A CN 201711130067 A CN201711130067 A CN 201711130067A CN 107982481 A CN107982481 A CN 107982481A
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medicine
gout
myrrh
tortoiseshell
desmodium
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孙思远
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Sichuan Yichuang Biotechnology Co Ltd
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Sichuan Yichuang Biotechnology Co Ltd
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
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    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/484Glycyrrhiza (licorice)
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    • A61K9/20Pills, tablets, discs, rods
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    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of pill medicine for treating gout according to the understanding mechanism of Chinese traditional treatment gout, each component and its mass parts ratio of the medicine are as follows:150~280g of frankincense, 150~650g of desmodium, 30~350g of rheum officinale, 100~350g of black soya bean, 20~70g of Schisandra chinensis, 30~150g of radix glycyrrhizae, 30~120g of cortex magnoliae officinalis, 30~120g of curcuma zedoary, 150~450g of tortoiseshell, 30~120g of dried orange peel, 100~160g of plantain seed, 30~70g of fructus amomi, 30~60g of myrrh, 50~150g of safflower;Medicine provided by the invention is a good Chinese prescription.

Description

A kind of pill medicine for treating gout and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for treating gout, particularly suffers from for gout The field of the pill medicine that person uses and preparation method thereof.
Background technology
Shown according to related document:Gout is by monosodium urate salt(MSU)Crystal correlation arthropathy caused by deposition, it is and fast Purine metabolic disorder and(Or)Hyperuricemia caused by underexcretion is directly related, refers in particular to acute characteristic arthritis and slow Property tophus disease, mainly include acute attack arthritis, tophus formation, tophaceous chornic arthritis, lithate kidney Sick and uric acid lithangiuria, severe one may occur in which joint deformity and renal insufficiency.Gout often with Central obesity, hyperlipidemia, Hypertension, diabetes B and cardiovascular disease etc. show.
So, a kind of Chinese medicine composition that can effectively treat gout how is just found, is that those skilled in the art urgently will Solve the problems, such as.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment gout, people gradually appreciate Chinese traditional treatment pain The advantages of wind, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment gout Present situation, the purpose of the invention is to provide a kind of pill medicine for treating gout, is got well early with solving patient with gout The problem of.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively be treated above-mentioned Gout.
To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is:A kind of pill for treating gout is provided Medicine and preparation method thereof, it is characterised in that each component and mass parts of the medicine are than as follows:
It is 150~280g of frankincense, 150~650g of desmodium, 30~350g of rheum officinale, 100~350g of black soya bean, 20~70g of Schisandra chinensis, sweet 30~150g of grass, 30~120g of cortex magnoliae officinalis, 30~120g of curcuma zedoary, 150~450g of tortoiseshell, 30~120g of dried orange peel, plantain seed 100~ 160g, 30~70g of fructus amomi, 30~60g of myrrh, 50~150g of safflower, auxiliary material:Appropriate starch.
A kind of pill medicine for treating gout and preparation method thereof, it is characterised in that each component and matter of the medicine Part is measured than as follows:
It is 180~250g of frankincense, 180~560g of desmodium, 38~310g of rheum officinale, 115~310g of black soya bean, 26~60g of Schisandra chinensis, sweet 38~130g of grass, 38~105g of cortex magnoliae officinalis, 38~105g of curcuma zedoary, 180~400g of tortoiseshell, 38~105g of dried orange peel, plantain seed 115~ 140g, 38~60g of fructus amomi, 38~52g of myrrh, 58~130g of safflower, auxiliary material:Appropriate starch.
A kind of pill medicine for treating gout and preparation method thereof, it is characterised in that each component and matter of the medicine Part is measured than as follows:
Frankincense 220g, desmodium 500g, rheum officinale 280g, black soya bean 280g, Schisandra chinensis 52g, radix glycyrrhizae 118g, cortex magnoliae officinalis 95g, curcuma zedoary 95g, Tortoiseshell 350g, dried orange peel 95g, plantain seed 120g, fructus amomi 52g, myrrh 45g, safflower 118g, auxiliary material:Appropriate starch.
A kind of pill medicine for treating gout and preparation method thereof, it is characterised in that system that described method includes following steps It is standby to form:
A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and drying, it is ground into superfine end according to mass parts ratio and treats With;
B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch are sieved, is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent(The granularity of its water-bindered pill is:3.9mm~4.0mm), and then dry, sealed packaging is Can.
A kind of pill medicine for treating gout and preparation method thereof, it is characterised in that the instructions of taking is:It will prepare Water pill medicine three times a day to take, once a dose in the morning, afternoon and evening, dosage 6.5g/time, warm water delivery service.15 days are one A course for the treatment of, treats 4~8 courses for the treatment of, checks:Blood uric acid recovers normal.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component:
Frankincense, nature and flavor:Acrid, bitter, warm, has the effect of blood-activating and qi-promoting analgesic, detumescence and promoting granulation, for treating chest impediment and cardialgia, gastral cavilty Pain, dysmenorrhoea Amenorrhea, postpartum stasis, abdominal mass abdominal pain, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore;
Desmodium, nature and flavor:Sweet in flavor, salty, cold nature, has removing dampness through diuresis and removing jaundice, inducing diuresis for treating strangurtia, the efficacy of removing toxicity for detumescence effect, for treating Jaundice with damp-heat pathogen, courage the are swollen disease such as hypochondriac pain, urolithiasis, heat gonorrhea, difficulty and pain in micturition, carbuncle swells furunculosis, snakebite and bugbite;
Rheum officinale, nature and flavor:It is bitter, cold in nature, it is nontoxic, there is the effect of purging heat logical intestines, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, for treating reality Hot constipation, stagnate not well abdominal pain, rush down dysentery, jaundice with damp-heat pathogen, blood-head tells nosebleed, hot eyes, pharynx swelling, abdominalgia with intestinal abscess, carbuncle swells furunculosis, hemostasis warp Close, traumatic injury, scald, upper gastrointestinal bleeding;
Black soya bean, nature and flavor:It is sweet, flat, there is the effect of benefiting shrewd head, nourishing the blood to expel wind, Li Shui, removing toxic substances, for treating deficiency of Yin polydipsia, head Dizzy blurred vision, body void hidrosis, lumbago due to the kidney deficiency, oedema oliguria, numbness pain contraction, numb in every limb, medicine food poisoning;
Schisandra chinensis, nature and flavor:It is sour, sweet, warm, there is the effect of convergence astringent method, nourishing generate fluid, kidney calming, for treating void of coughing long Asthma, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, injury thirst, feeble pulse of losing heart, Heat Diabetes, palpitation and insomnia;
Radix glycyrrhizae, nature and flavor:It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swell in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, the disease such as ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning;
Cortex magnoliae officinalis, nature and flavor:It is bitter, pungent, warm-natured, there is the effect of gas consumption product, eliminating dampness except full, relieving asthma, for treating dyspepsia gas The diseases such as stagnant, abdominal distention constipation, damp retention in middle-jiao, abdominal swelling and diarrhea, phlegm stops up the circulation of vital energy in the wrong direction, chest full of cough;
Curcuma zedoary, nature and flavor:Toil, temperature, have the effect of blood-breaking, Xiao Ji Zhi Tong, for treat pained vim and vigour, eating accumulation, Abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhoea, abdominal mass knurl lump in the abdomen, traumatic injury, be additionally operable to abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, Accumulation, abdominal mass lump, women's blood stasis, traumatic injury are had a pain eating accumulation, and it is antitumor that modern pharmacology shows that oriental wormwood has Effect:Its aromatic turmeric oil preparation is in vitro to the L615 leukaemia and ascitic type of Mouse Ehrlich Carcinoma Cells, 615 mouse inbred lines The growth of a variety of knurl strains such as liver cancer cells has obvious suppression and destruction.Clinic makees intratumoral injection uterine neck with oil of zedoary turmeric Cancer, after treatment visible tumor tissue necrosis come off, local lymphocytes infiltration, some cases lump disappear, uterine neck is smooth, prompt cowherb Art plays the role of directly killing oncocyte;
Tortoiseshell, nature and flavor:It is salty sweet, flat, there is the effect of enriching yin, checking exuberance of yang, kidney tonifying, strong bone, for treating the deficiency of the kidney yin, hectic fever due to yin labor Heat, haematemesis, bleeding from five sense organs or subcutaneous tissue, chronic cough, seminal emission, uterine bleeding, band under, pain in the back, the atrophic debility of bones, wind formation from yin deficiency, protracted dysentery, chronic malaria, hemorrhoid, children's fontanel Do not conform to;
Dried orange peel, nature and flavor:Warm-natured, acrid flavour, bitter, have in regulating qi-flowing for strengthening spleen, tune, eliminating dampness, clears phlegm, for treating taste gas Stagnant abdominal fullness and distention or pain, indigestion, the abdominal distension uncomfortable in chest in wet turbid resistance, indigestion and loss of appetite loose stool, the cough and asthma of phlegm obstructing lung, also For chest gastral cavity turgor, deficiency of food vomiting and diarrhoea, coughing with a lot of sputum;
Plantain seed, nature and flavor:It is sweet in flavor, cold in nature, there is the effect for the treatment of stranguria reducing fever and causing diuresis, excreting dampness antidiarrheal, improving eyesight, eliminating the phlegm, for treating The diseases such as puckery pain of heat gonorrhea, oedema turgor, summer heat damp diarrhea, red eye, swell pain, phlegm-heat cough;
Fructus amomi, nature and flavor:It is acrid flavour, warm-natured, there is the effect of dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy antiabortive, for treat it is wet it is turbid in Resistance, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, vomiting and diarrhea, pernicious vomiting, fetal irritability;
Myrrh, nature and flavor:It is acrid flavour, hardship, mild-natured, there is the effect of scattered stasis pain, detumescence and promoting granulation, for treating chest impediment and cardialgia, gastral cavilty Pain, dysmenorrhoea Amenorrhea, postpartum stasis, Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, traumatic injury, carbuncle swells sore;
Safflower, nature and flavor:It is acrid flavour, warm-natured, there is the effect of promoting blood circulation can be through, stasis-dispelling and pain-killing, for treating Amenorrhea, dysmenorrhoea, the postpartum stasis of blood The diseases such as resistance abdominal pain, born of the same parents' numbness is pained, and a lump in the abdomen causing distension and pain, traumatic injury, arthralgia, middle windage yaw are completed, macula.
Medicine of the present invention is the principle based on Chinese traditional treatment gout, is recognized from the pathomechanism according to gout and pharmacological action For:With regard to gout, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.
Embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned gout, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail:
Embodiment 1:
A kind of pill medicine for treating gout, it is characterised in that each component and mass parts of the medicine are than as follows:
Frankincense 220g, desmodium 500g, rheum officinale 280g, black soya bean 280g, Schisandra chinensis 52g, radix glycyrrhizae 118g, cortex magnoliae officinalis 95g, curcuma zedoary 95g, Tortoiseshell 350g, dried orange peel 95g, plantain seed 120g, fructus amomi 52g, myrrh 45g, safflower 118g, auxiliary material:Appropriate starch.
Embodiment 2:
A kind of pill medicine for treating gout, it is characterised in that each component and mass parts of the medicine are than as follows:
Frankincense 250g, desmodium 560g, rheum officinale 310g, black soya bean 310g, Schisandra chinensis 60g, radix glycyrrhizae 130g, cortex magnoliae officinalis 105g, curcuma zedoary 105g, tortoiseshell 400g, dried orange peel 105g, plantain seed 140g, fructus amomi 60g, myrrh 52g, safflower 130g, auxiliary material:Appropriate starch.
Embodiment 3:
A kind of pill medicine for treating gout, it is characterised in that each component and mass parts of the medicine are than as follows:
Frankincense 280g, desmodium 650g, rheum officinale 350g, black soya bean 350g, Schisandra chinensis 70g, radix glycyrrhizae 150g, cortex magnoliae officinalis 120g, curcuma zedoary 120g, tortoiseshell 450g, dried orange peel 120g, plantain seed 160g, fructus amomi 70g, myrrh 60g, safflower 150g, auxiliary material:Appropriate starch.
Model case:
Through clinical conditions patient with gout totally 1365, the age is 810 of more than 57 years old, and only 555 are less than 57 years old. Blood uric acid recovers normally have 915, effective 327, invalid 123 in 1365 patients.Total effective rate is up to 91%.

Claims (3)

1. a kind of pill medicine for treating gout, it is characterised in that each component and its mass parts of the medicine are than following institute Show:
It is 150~280g of frankincense, 150~650g of desmodium, 30~350g of rheum officinale, 100~350g of black soya bean, 20~70g of Schisandra chinensis, sweet 30~150g of grass, 30~120g of cortex magnoliae officinalis, 30~120g of curcuma zedoary, 150~450g of tortoiseshell, 30~120g of dried orange peel, plantain seed 100~ 160g, 30~70g of fructus amomi, 30~60g of myrrh, 50~150g of safflower, auxiliary material:Appropriate starch.
2. it is according to claim 1 treatment gout pill medicine, it is characterised in that each component of the medicine and its Mass parts are than as follows:
It is 180~250g of frankincense, 180~560g of desmodium, 38~310g of rheum officinale, 115~310g of black soya bean, 26~60g of Schisandra chinensis, sweet 38~130g of grass, 38~105g of cortex magnoliae officinalis, 38~105g of curcuma zedoary, 180~400g of tortoiseshell, 38~105g of dried orange peel, plantain seed 115~ 140g, 38~60g of fructus amomi, 38~52g of myrrh, 58~130g of safflower, auxiliary material:Appropriate starch.
3. the pill medicine of the treatment gout according to claim 1 to 2, it is characterised in that each component of the medicine And its mass parts are than as follows:
Frankincense 220g, desmodium 500g, rheum officinale 280g, black soya bean 280g, Schisandra chinensis 52g, radix glycyrrhizae 118g, cortex magnoliae officinalis 95g, curcuma zedoary 95g, Tortoiseshell 350g, dried orange peel 95g, plantain seed 120g, fructus amomi 52g, myrrh 45g, safflower 118g, auxiliary material:Appropriate starch.
CN201711130067.7A 2017-11-15 2017-11-15 A kind of pill medicine for treating gout and preparation method thereof Withdrawn CN107982481A (en)

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Application publication date: 20180504