CN107961001A - Appraisal procedure, device and the atherosclerosis detector of Degree of arteriosclerosis - Google Patents

Appraisal procedure, device and the atherosclerosis detector of Degree of arteriosclerosis Download PDF

Info

Publication number
CN107961001A
CN107961001A CN201711391505.5A CN201711391505A CN107961001A CN 107961001 A CN107961001 A CN 107961001A CN 201711391505 A CN201711391505 A CN 201711391505A CN 107961001 A CN107961001 A CN 107961001A
Authority
CN
China
Prior art keywords
pulse wave
destination object
ppg signals
ppg
characteristic point
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711391505.5A
Other languages
Chinese (zh)
Inventor
苗芬
李烨
刘记奎
刘增丁
闻博
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Institute of Advanced Technology of CAS
Original Assignee
Shenzhen Institute of Advanced Technology of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Institute of Advanced Technology of CAS filed Critical Shenzhen Institute of Advanced Technology of CAS
Priority to CN201711391505.5A priority Critical patent/CN107961001A/en
Publication of CN107961001A publication Critical patent/CN107961001A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007Evaluating blood vessel condition, e.g. elasticity, compliance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802Sensor mounted on worn items
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Cardiology (AREA)
  • Signal Processing (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

The present invention provides a kind of appraisal procedure of Degree of arteriosclerosis, device and atherosclerosis detector, it is related to artery sclerosis detection technique field, this method includes:Gather the PPG signals of at least two body part of destination object;Detect the characteristic point of each PPG signals;According to the characteristic point of each PPG signals, the pulse wave conduction speed of the destination object is determined;Based on the pulse wave conduction speed pre-established and the correspondence at age, the Degree of arteriosclerosis of the destination object is assessed.The mode of present invention detection Degree of arteriosclerosis is more simple and feasible.

Description

Appraisal procedure, device and the atherosclerosis detector of Degree of arteriosclerosis
Technical field
The present invention relates to artery sclerosis detection technique field, more particularly, to a kind of appraisal procedure of Degree of arteriosclerosis, Device and atherosclerosis detector.
Background technology
Angiocardiopathy is to seriously endanger the major disease of human health, and arteriosclerotic lesion is most of cardiovascular diseases The common pathophysiological basis of disease, the arteriosclerotic lesion of any body part may all cause the ischemic work(of respective regions Can, such as coronary heart disease, cerebral apoplexy etc..Therefore, the hardenability for knowing artery is the key of Prevention of cardiovascular disease level.
Present artery sclerosis detection device is broadly divided into invasive detection and two class of Non-invasive detection, invasive detection device master Degree of arteriosclerosis is detected by the way of arteriography, but the detection device based on angiography belongs to and has Invasive operation, has the characteristics that detection of complex, expensive, sensitivity is low.Non-invasive detection equipment can be applied and be based on ultrasonic imaging Vascular compliance detection the methods of, equally have cost it is high, it is complicated, need specialized guidance, be unfavorable for portable monitoring The problems such as.
For existing equipment it is complex to the detection method of Degree of arteriosclerosis the problem of, not yet propose at present effective Solution.
The content of the invention
In view of this, it is an object of the invention to provide a kind of appraisal procedure of Degree of arteriosclerosis, device and artery are hard Change detector, to improve the problem of existing equipment is complex to the detection method of Degree of arteriosclerosis.
To achieve these goals, the technical solution that the embodiment of the present invention uses is as follows:
In a first aspect, an embodiment of the present invention provides a kind of appraisal procedure of Degree of arteriosclerosis, including:Gather target pair As the PPG signals of at least two body parts;Detect the characteristic point of each PPG signals;According to the characteristic point of each PPG signals, determine The pulse wave conduction speed of destination object;Based on the pulse wave conduction speed pre-established and the correspondence at age, mesh is assessed Mark the Degree of arteriosclerosis of object.
Further, the step of PPG signals of above-mentioned at least two body part of collection destination object, including:Pass through photoelectricity The PPG signals of at least two body part of volume pulsation wave collector synchronous acquisition destination object.
Further, the step of characteristic point of each PPG signals of above-mentioned detection, including:Each PPG signals are carried out at interference filtering Reason;Detect the characteristic point of each PPG signals after interference filtering is handled.
Further, the step of characteristic point of each PPG signals of the above-mentioned detection after interference filtering is handled, including:Based on difference Divide threshold method, detect the characteristic point of each PPG signals after interference filtering is handled, characteristic point includes PPG starting points, PPG peak points With PPG first differential maximum of points.
Further, the above-mentioned characteristic point according to each PPG signals, the step of determining the pulse wave conduction speed of destination object, Including:According to the time gap of individual features point in multiple PPG signals, pulse wave translation time is determined;According to what is obtained in advance The biological information of destination object, determines the length of vessel of destination object;Biological information includes one kind in height, brachium and leg length It is or a variety of;According to length of vessel and pulse wave translation time, the pulse wave conduction speed of destination object is determined.
Further, it is above-mentioned according to length of vessel and pulse wave translation time, determine the pulse wave conduction speed of destination object The step of, including:Pulse wave conduction speed using the ratio of length of vessel and pulse wave translation time as destination object.
Further, the establishment step of above-mentioned pulse wave conduction speed and the correspondence at age includes:The default quantity of collection Sample of users age and pulse wave conduction speed;Based on collection result, change of the pulse wave conduction speed with the age is drawn Change curve.
Further, the step of Degree of arteriosclerosis of above-mentioned assessment destination object, including:From pulse wave conduction speed with year The pulse wave conduction speed corresponding age of destination object is searched in the change curve in age;According to the pulse transit of destination object At the speed corresponding age, assess the Degree of arteriosclerosis of destination object.
Second aspect, the embodiment of the present invention also provide a kind of apparatus for evaluating of Degree of arteriosclerosis, including:Signal acquisition mould Block, for gathering the PPG signals of at least two body part of destination object;Characteristic point detection module, for detecting each PPG signals Characteristic point;Conduction of velocity determining module, for the characteristic point according to each PPG signals, determines the pulse transit of destination object Speed;Artery evaluation module, for based on the pulse wave conduction speed pre-established and the correspondence at age, assessing target pair The Degree of arteriosclerosis of elephant.
The third aspect, an embodiment of the present invention provides a kind of atherosclerosis detector, including processor and photoelectricity volume arteries and veins Fight ripple collector;Photoplethysmographic collector is used for the PPG signals for gathering at least two body part of destination object;Processing Computer program is stored with device, computer program is performed when being run by processor such as the method for any one of first aspect.
An embodiment of the present invention provides a kind of appraisal procedure of Degree of arteriosclerosis, device and atherosclerosis detector, leads to The characteristic point of the PPG signals of the multiple body parts of detected target object is crossed, can determine the pulse transit speed of the destination object Degree, and then based on the pulse wave conduction speed pre-established and the correspondence at age, the artery for assessing the destination object is hard Change degree.The detection method of this Degree of arteriosclerosis is eased feasible, is also applied for domestic medicine, by portable or wear The PPG signals of formula equipment collection user body parts are worn, analyze PPG signals the artery sclerosis journey that can assess the user Degree, user can easily know artery situation, improve the preventive effect to angiocardiopathy.
Other feature and advantage of the disclosure will illustrate in the following description, alternatively, Partial Feature and advantage can be with Deduce from specification or unambiguously determine, or by implement the disclosure above-mentioned technology it can be learnt that.
To enable the above objects, features and advantages of the present invention to become apparent, preferred embodiment cited below particularly, and coordinate Appended attached drawing, is described in detail below.
Brief description of the drawings
, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution of the prior art Embodiment or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, in describing below Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor Put, other attached drawings can also be obtained according to these attached drawings.
Fig. 1 shows a kind of appraisal procedure flow chart for Degree of arteriosclerosis that the embodiment of the present invention is provided;
Fig. 2 shows a kind of signal acquisition schematic diagram that the embodiment of the present invention is provided;
Fig. 3 shows a kind of PPG characteristic points detects schematic diagram that the embodiment of the present invention is provided;
Fig. 4 shows a kind of pulse wave translation time schematic diagram that the embodiment of the present invention is provided;
Fig. 5 shows a kind of PWV distribution maps for different age group that the embodiment of the present invention is provided;
Fig. 6 shows a kind of structure diagram of the apparatus for evaluating for Degree of arteriosclerosis that the embodiment of the present invention is provided;
Fig. 7 shows a kind of structure diagram for atherosclerosis detector that the embodiment of the present invention is provided.
Embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with attached drawing to the present invention Technical solution be clearly and completely described, it is clear that described embodiment is part of the embodiment of the present invention, rather than Whole embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creative work premise Lower all other embodiments obtained, belong to the scope of protection of the invention.
Existing arteriosclerosis detecting method is mostly complex, and many testing principles are all the arterial vascular bullets of measurement Property, the vascular compliance detection such as based on ultrasonic imaging, the totality based on reflective wave augmentation index quantitative response arterial system Elasticity, arterial elasticity detection based on plane strain method etc., mostly cumbersome, it is not high to measure the accuracy of arterial elasticity, and And the artery sclerosis assay device structures of the application above method are complicated, it is necessary to specialized guidance is just usable, are not easy to portable inspection Survey, and cost is higher, it is difficult to applied in domestic medicine.
To improve the above problem, a kind of appraisal procedure of Degree of arteriosclerosis provided in an embodiment of the present invention, device and dynamic Arteries and veins hardens detector, which can be applied in Wearable, can also be applied to such as hand being connected with signal picker In the terminal devices such as mechanical, electrical brain, for assessing Degree of arteriosclerosis.The technology can use corresponding hardware and software to realize, with Under describe in detail to the embodiment of the present invention.
Embodiment one:
A kind of appraisal procedure of Degree of arteriosclerosis is present embodiments provided, this method can be held by atherosclerosis detector OK, which can be portable set, and in one embodiment, which is wearable Equipment, in another embodiment, the atherosclerosis detector are the portable terminal device for including signal picker and processor, letter Number collector and processor can be integrally disposed, can also physical separation set, in practical applications, which can also adopt With mobile phone, tablet computer etc., portable inspectiont can be achieved.A kind of appraisal procedure of Degree of arteriosclerosis shown in Figure 1 Flow chart, specifically includes following steps:
Step S102, gathers the PPG signals of at least two body part of destination object.
In practical applications, can be by photoplethysmographic collector synchronous acquisition destination object (that is, positive receive Tester) at least two body parts PPG (photoplethysmograph, photoplethysmographic) signal.Photoelectricity volume Pulse wave collector namely above-mentioned signal picker, for gathering PPG signals.In order to make signal acquisition result more accurate, light The signal sampling rate of Power Capacity pulse wave collector can be not less than 500Hz.
The body part of destination object can include but is not limited to:Finger, wrist, ear, toe, ankle etc.;For ease of Understand, a kind of signal acquisition schematic diagram shown in Figure 2, illustrate collectable ear PPG, wrist PPG, finger tip PPG and Toe point PPG;Due to the bilateral symmetry of human body, because in actual acquisition, and left ear PPG, auris dextra PPG etc. can be subdivided into.
Step S104, detects the characteristic point of each PPG signals.
Present embodiments provide a kind of embodiment of characteristic point detection:
(1) interference filtering processing is carried out to each PPG signals;That is, being pre-processed to the original PPG signals of collection, filter The interference such as baseline drift caused by except being moved due to human body respiration etc..
(2) characteristic point of each PPG signal of the detection after interference filtering is handled.Specifically, difference threshold algorithm can be based on, The characteristic point of each PPG signals after interference filtering is handled is detected, characteristic point includes PPG starting points (that is, PPG troughs), PPG peaks It is worth point (that is, PPG wave crests) and PPG first differentials maximum of points (first derivative maximum).Specifically, it may refer to Fig. 3 institutes A kind of PPG characteristic points detects schematic diagram shown, the A points in Fig. 3 are PPG starting points, and B points are PPG first differential maximum of points, C points For PPG peak points.
Step S106, according to the characteristic point of each PPG signals, determines the pulse wave conduction speed of destination object.Due to human body There is a certain distance, the PPG signals that each position measures also have certain difference, can specifically be embodied between each position Time gap between the individual features point of PPG signals, such as, has between the wave crest of left ear PPG and the wave crest of left finesse PPG Regular hour distance, has regular hour distance etc. between the trough of left ear PPG and the trough of wrist PPG.According to multiple Time gap between PPG signals individual features point, and the body part corresponding to multiple PPG signals, it may be determined that pulse Ripple conduction of velocity.
In specific implementation, step S106 is referred to following steps and determines pulse wave conduction speed:
(1) according to the time gap of individual features point in multiple PPG signals, pulse wave translation time is determined.Specifically, from Being chosen in the PPG signals of collection can be with multiple PPG signal of comparative feature point, multiple PPG signals pair for comparative feature point The body part answered is preferably body side, can be that left hand is left so that the corresponding PPG signals of two body parts compare as an example Foot, right hand right crus of diaphragm, left ear left hand, the auris dextra right hand, left ear left foot, auris dextra right crus of diaphragm etc..Specifically, it may refer to one shown in Fig. 4 Kind pulse wave translation time schematic diagram, illustrates the corresponding PPG signals of two body parts in the figure, two-way PPG signals Time gap between starting point is PTT_Bottom (also known as distance between trough), the time interval between the trough of two-way PPG signals From for PTT_Peak (also known as corrugation pitch from), the distance between first derivative maximum of two-way PPG signals is PTT_ MaxDeri.Further, it is possible to which above three time gap is averaged, pulse wave translation time PTT (Pulse are obtained Transit Time).If multiple PPG signals for comparing, obtained multiple time gaps can finally be averaged, Determine PTT.
(2) biological information for the destination object that basis obtains in advance, determines the length of vessel of destination object;Biological information bag Include the one or more in height, brachium and leg length.For example, blood vessel can be obtained according to height and the product of empirical scalar value Length, or length of vessel is determined by the mode such as table look-up, each body counted by big data can be recorded in form and is believed Cease corresponding length of vessel.
(3) according to length of vessel and pulse wave translation time, the pulse wave conduction speed of destination object is determined.Specifically, Pulse wave conduction speed that can be using the ratio of length of vessel and pulse wave translation time as destination object.Assuming that length of vessel For L, pulse wave translation time PTT, then pulse wave conduction speed PWV=L/PTT.
Step S108, based on the pulse wave conduction speed pre-established and the correspondence at age, assesses destination object Degree of arteriosclerosis.
Specifically, pulse wave conduction speed and the correspondence at age can be obtained by way of big data statistics, In a kind of embodiment, age and the pulse wave conduction speed of the sample of users of default quantity are gathered;Based on collection result, paint Pulse wave conduction speed processed with the age change curve.Such as, 5000 people's above demographic datas are collected and is used for all age group The statistics of PWV (Pulse Wave Velocity, pulse wave conduction speed), wherein each age bracket number is more than 50 people, And curves of the PWV with change of age is drawn, a kind of PWV distribution maps of different age group shown in Fig. 5 are for details, reference can be made to, in the figure Curves of the PWV with change of age is illustrated, shows average value curve, and two with average value+1SD and -1SD Curve, wherein, 1SD represents a standard deviation, it can be seen that PWV increases with being incremented by for age.Empirical tests are known, young PWV is 1200cm/s for each person, and the average PWV of old group is 1400cm/s, and then it is larger to show that PWV has for all ages and classes Discrimination, it was demonstrated that the scheme that the present embodiment is proposed has feasibility.
Since abovementioned steps have determined that the pulse wave conduction speed of destination object, from pulse wave conduction speed with The pulse wave conduction speed corresponding age of destination object is searched in the change curve at age;Further according to the pulse wave of destination object The conduction of velocity corresponding age, you can assess the Degree of arteriosclerosis of destination object.Such as, the pulse transit speed of destination object The corresponding age is spent more higher than the age of destination object, then the Degree of arteriosclerosis of destination object is higher.
In the above method of the present embodiment, by the characteristic point of the PPG signals of the multiple body parts of detected target object, just It can determine that the pulse wave conduction speed of the destination object, so it is corresponding with the age based on the pulse wave conduction speed pre-established Relation, assesses the Degree of arteriosclerosis of the destination object.The detection method of this Degree of arteriosclerosis is eased feasible, by Measurable photoplethysmographic and perform the above method portable medical device or wearable device i.e. can be achieved, preferably Cost is reduced, therefore can also be measured in domestic medicine by user's complete independently, user can easily know artery feelings Condition, improves the preventive effect to angiocardiopathy.
The above method is not only simple and convenient, effectively reduces the cost of the artery sclerosis detection device using this method, and It is this preferably to realize the assessment of body local and overall Degree of arteriosclerosis by the way of more PPG convergence analysis, Make artery sclerosis testing result more comprehensively reliable.
Embodiment two:
It is dynamic an embodiment of the present invention provides one kind for the appraisal procedure of the Degree of arteriosclerosis provided in embodiment one The apparatus for evaluating of arteries and veins hardenability, the device can be arranged on artery sclerosis detection device, a kind of artery shown in Figure 6 The structure diagram of the apparatus for evaluating of hardenability, including with lower module:
Signal acquisition module 602, for gathering the PPG signals of at least two body part of destination object;
Characteristic point detection module 604, for detecting the characteristic point of each PPG signals;
Conduction of velocity determining module 606, for the characteristic point according to each PPG signals, determines that the pulse wave of destination object passes Lead speed;
Artery evaluation module 608, for based on the pulse wave conduction speed pre-established and the correspondence at age, assessment The Degree of arteriosclerosis of destination object.
In the above device of the present embodiment, by the characteristic point of the PPG signals of the multiple body parts of detected target object, just It can determine that the pulse wave conduction speed of the destination object, so it is corresponding with the age based on the pulse wave conduction speed pre-established Relation, assesses the Degree of arteriosclerosis of the destination object.The detection method of this Degree of arteriosclerosis is eased feasible, Suitable for domestic medicine, the PPG signals of user body parts are gathered by portable or Wearable, PPG signals are carried out Analysis can assess the Degree of arteriosclerosis of the user, and user can easily know artery situation, improve to cardiovascular disease The preventive effect of disease.
The technique effect of the device that the present embodiment is provided, its realization principle and generation is identical with previous embodiment, for letter Describe, device embodiment part does not refer to part, refers to corresponding contents in preceding method embodiment.
Embodiment three:
Corresponding to the appraisal procedure and device of foregoing Degree of arteriosclerosis, a kind of artery sclerosis detection is present embodiments provided Instrument, including processor and photoplethysmographic collector;
Photoplethysmographic collector is used for the PPG signals for gathering at least two body part of destination object;
Computer program is stored with processor, computer program performs embodiment one such as when being run by processor and provides Degree of arteriosclerosis appraisal procedure.
Above-mentioned atherosclerosis detector can be portable set, in one embodiment, the atherosclerosis detector For Wearable, in another embodiment, which is to include signal picker and processor just Take terminal, signal picker and processor can be integrally disposed, can also physical separation set, in practical applications, the processing Device can also use mobile phone, computer etc. to realize.
Fig. 7 is a kind of structure diagram of atherosclerosis detector provided in an embodiment of the present invention, including:Processor 70, Memory 71, bus 72 and photoplethysmographic collector 73, processor 70, photoplethysmographic collector 73 and storage Device 71 is connected by bus 72;Processor 70 is used to perform the executable module stored in memory 71, such as computer program.
Wherein, memory 71 may include high-speed random access memory (RAM, Random Access Memory), Non-labile memory (non-volatile memory), for example, at least a magnetic disk storage may be further included.By extremely A few photoplethysmographic collector 73 (can be wired or wireless connection) realize the system network element with it is at least one Communication connection between other network elements, can use internet, wide area network, local network, Metropolitan Area Network (MAN) etc..
Bus 72 can be isa bus, pci bus or eisa bus etc..It is total that bus can be divided into address bus, data Line, controlling bus etc..For ease of representing, only represented in Fig. 7 with a four-headed arrow, it is not intended that an only bus or one The bus of type.
Photoplethysmographic collector 73 can gather the corresponding PPG signals of multiple body parts, and by wired or Bus is wirelessly transferred to, so as to pass to processor and memory.
Wherein, memory 71 is used for storage program, and processor 70 performs the above method after execute instruction is received, preceding State the method performed by the device that the stream process that any embodiment of the embodiment of the present invention discloses defines and can be applied to processor 70 In, or realized by processor 70.
Processor 70 is probably a kind of IC chip, has the disposal ability of signal.During realization, above-mentioned side Each step of method can be completed by the integrated logic circuit of the hardware in processor 70 or the instruction of software form.Above-mentioned Processor 70 can be general processor, including central processing unit (Central Processing Unit, abbreviation CPU), network Processor (Network Processor, abbreviation NP) etc.;It can also be digital signal processor (Digital Signal Processing, abbreviation DSP), application-specific integrated circuit (Application Specific Integrated Circuit, referred to as ASIC), ready-made programmable gate array (Field-Programmable Gate Array, abbreviation FPGA) or other are programmable Logical device, discrete gate or transistor logic, discrete hardware components.It can realize or perform in the embodiment of the present invention Disclosed each method, step and logic diagram.General processor can be microprocessor or the processor can also be appointed What conventional processor etc..The step of method with reference to disclosed in the embodiment of the present invention, can be embodied directly in hardware decoding processing Device performs completion, or performs completion with the hardware in decoding processor and software module combination.Software module can be located at Machine memory, flash memory, read-only storage, programmable read only memory or electrically erasable programmable memory, register etc. are originally In the storage medium of field maturation.The storage medium is located at memory 71, and processor 70 reads the information in memory 71, with reference to Its hardware completes the step of above method.
It is apparent to those skilled in the art that for convenience and simplicity of description, the system of foregoing description Specific work process, may be referred to the corresponding process in previous embodiment, details are not described herein.
The calculating of the appraisal procedure of the Degree of arteriosclerosis that the embodiment of the present invention is provided, device and atherosclerosis detector Machine program product, including the computer-readable recording medium of program code is stored, the instruction that said program code includes can use In the method described in previous methods embodiment that performs, specific implementation can be found in embodiment of the method, and details are not described herein.
If the function is realized in the form of SFU software functional unit and is used as independent production marketing or in use, can be with It is stored in a computer read/write memory medium.Based on such understanding, technical scheme is substantially in other words The part to contribute to the prior art or the part of the technical solution can be embodied in the form of software product, the meter Calculation machine software product is stored in a storage medium, including some instructions are used so that a computer equipment (can be People's computer, server, or network equipment etc.) perform all or part of step of each embodiment the method for the present invention. And foregoing storage medium includes:USB flash disk, mobile hard disk, read-only storage (ROM, Read-Only Memory), arbitrary access are deposited Reservoir (RAM, Random Access Memory), magnetic disc or CD etc. are various can be with the medium of store program codes.
Finally it should be noted that:Embodiment described above, is only the embodiment of the present invention, to illustrate the present invention Technical solution, rather than its limitations, protection scope of the present invention is not limited thereto, although with reference to the foregoing embodiments to this hair It is bright to be described in detail, it will be understood by those of ordinary skill in the art that:Any one skilled in the art The invention discloses technical scope in, it can still modify the technical solution described in previous embodiment or can be light It is readily conceivable that change, or equivalent substitution is carried out to which part technical characteristic;And these modifications, change or replacement, do not make The essence of appropriate technical solution departs from the spirit and scope of technical solution of the embodiment of the present invention, should all cover the protection in the present invention Within the scope of.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.

Claims (10)

  1. A kind of 1. appraisal procedure of Degree of arteriosclerosis, it is characterised in that including:
    Gather the PPG signals of at least two body part of destination object;
    Detect the characteristic point of each PPG signals;
    According to the characteristic point of each PPG signals, the pulse wave conduction speed of the destination object is determined;
    Based on the pulse wave conduction speed pre-established and the correspondence at age, the artery sclerosis journey of the destination object is assessed Degree.
  2. 2. according to the method described in claim 1, it is characterized in that, collection destination object at least two body part The step of PPG signals, including:
    Pass through the PPG signals of at least two body part of photoplethysmographic collector synchronous acquisition destination object.
  3. 3. according to the method described in claim 1, it is characterized in that, the step of the characteristic point of each PPG signals of the detection, Including:
    Interference filtering processing is carried out to each PPG signals;
    Detect the characteristic point of each PPG signals after interference filtering is handled.
  4. 4. the according to the method described in claim 3, it is characterized in that, each PPG of the detection after interference filtering is handled The step of characteristic point of signal, including:
    Based on difference threshold algorithm, the characteristic point of each PPG signals after interference filtering is handled is detected, the characteristic point includes PPG starting points, PPG peak points and PPG first differential maximum of points.
  5. 5. according to the method described in claim 1, it is characterized in that, the characteristic point according to each PPG signals, determines institute The step of stating the pulse wave conduction speed of destination object, including:
    According to the time gap of individual features point in multiple PPG signals, pulse wave translation time is determined;
    According to the biological information of the destination object obtained in advance, the length of vessel of the destination object is determined;The body Information includes the one or more in height, brachium and leg length;
    According to the length of vessel and the pulse wave translation time, the pulse wave conduction speed of the destination object is determined.
  6. It is 6. according to the method described in claim 5, it is characterized in that, described according to the length of vessel and the pulse transit Time, the step of determining the pulse wave conduction speed of the destination object, including:
    Pulse wave conduction speed using the ratio of the length of vessel and the pulse wave translation time as the destination object.
  7. 7. according to the method described in claim 1, it is characterized in that, the pulse wave conduction speed and the correspondence at age Establishment step includes:
    The age of the sample of users of the default quantity of collection and pulse wave conduction speed;
    Based on collection result, change curve of the pulse wave conduction speed with the age is drawn.
  8. 8. the method according to the description of claim 7 is characterized in that Degree of arteriosclerosis of the assessment destination object Step, including:
    The pulse wave conduction speed pair of the destination object is searched in change curve from the pulse wave conduction speed with the age The age answered;
    According to the pulse wave conduction speed of the destination object corresponding age, the artery sclerosis journey of the destination object is assessed Degree.
  9. A kind of 9. apparatus for evaluating of Degree of arteriosclerosis, it is characterised in that including:
    Signal acquisition module, for gathering the PPG signals of at least two body part of destination object;
    Characteristic point detection module, for detecting the characteristic point of each PPG signals;
    Conduction of velocity determining module, for the characteristic point according to each PPG signals, determines that the pulse wave of the destination object passes Lead speed;
    Artery evaluation module, for based on the pulse wave conduction speed pre-established and the correspondence at age, assessing the mesh Mark the Degree of arteriosclerosis of object.
  10. 10. a kind of atherosclerosis detector, it is characterised in that including processor and photoplethysmographic collector;
    The photoplethysmographic collector is used for the PPG signals for gathering at least two body part of destination object;
    Computer program is stored with the processor, the computer program performs such as right when being run by the processor It is required that 1 to 8 any one of them method.
CN201711391505.5A 2017-12-20 2017-12-20 Appraisal procedure, device and the atherosclerosis detector of Degree of arteriosclerosis Pending CN107961001A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711391505.5A CN107961001A (en) 2017-12-20 2017-12-20 Appraisal procedure, device and the atherosclerosis detector of Degree of arteriosclerosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711391505.5A CN107961001A (en) 2017-12-20 2017-12-20 Appraisal procedure, device and the atherosclerosis detector of Degree of arteriosclerosis

Publications (1)

Publication Number Publication Date
CN107961001A true CN107961001A (en) 2018-04-27

Family

ID=61995656

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711391505.5A Pending CN107961001A (en) 2017-12-20 2017-12-20 Appraisal procedure, device and the atherosclerosis detector of Degree of arteriosclerosis

Country Status (1)

Country Link
CN (1) CN107961001A (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108852307A (en) * 2018-05-24 2018-11-23 重庆理工大学 A kind of non-contact noninvasive Arteriosclerosis detecting device
CN109730723A (en) * 2019-03-11 2019-05-10 京东方科技集团股份有限公司 Determine method, artery sclerosis detection device and the system of pulse transit time
CN110710960A (en) * 2019-09-12 2020-01-21 东莞市康助医疗科技有限公司 Arterial blood vessel age estimation method and device
CN110881967A (en) * 2018-09-10 2020-03-17 深圳市迈迪优科技有限公司 Non-invasive multi-segment peripheral arterial vessel elastic function detection method and instrument thereof
CN110960199A (en) * 2019-12-24 2020-04-07 中国人民解放军陆军军医大学第一附属医院 System for double-variable measurement of arteriosclerosis degree
CN111000537A (en) * 2019-12-24 2020-04-14 中国人民解放军陆军军医大学第一附属医院 Method for correcting influence of age, sex and blood pressure on pulse wave propagation speed
CN112274120A (en) * 2020-10-28 2021-01-29 河北工业大学 Noninvasive arteriosclerosis detection method and device based on one-way pulse wave
CN112274121A (en) * 2020-10-28 2021-01-29 河北工业大学 Noninvasive arteriosclerosis detection method and device based on multipath pulse waves
CN113229787A (en) * 2021-03-22 2021-08-10 安庆师范大学 Blood vessel age estimation and effectiveness evaluation method based on pulse signal shape characteristics
CN113303774A (en) * 2020-02-26 2021-08-27 Oppo广东移动通信有限公司 Wearable equipment
CN113598724A (en) * 2021-09-03 2021-11-05 上海市高血压研究所 Device for assessing cardiovascular autonomic nerve function
US11863937B2 (en) 2021-03-30 2024-01-02 Sonova Ag Binaural hearing system for providing sensor data indicative of a physiological property, and method of its operation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101977546A (en) * 2008-03-19 2011-02-16 欧姆龙健康医疗事业株式会社 Electronic blood pressure gauge for measuring blood pressure by using volume compensation method
US8195261B2 (en) * 2005-11-14 2012-06-05 Konica Minolta Sensing, Inc. Vital information measuring device
CN105873503A (en) * 2013-12-25 2016-08-17 旭化成株式会社 Cardiac pulse waveform measurement device, portable device, medical device system, and vital sign information communication system
CN107088071A (en) * 2016-02-17 2017-08-25 松下知识产权经营株式会社 Bioinformation detecting device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8195261B2 (en) * 2005-11-14 2012-06-05 Konica Minolta Sensing, Inc. Vital information measuring device
CN101977546A (en) * 2008-03-19 2011-02-16 欧姆龙健康医疗事业株式会社 Electronic blood pressure gauge for measuring blood pressure by using volume compensation method
CN105873503A (en) * 2013-12-25 2016-08-17 旭化成株式会社 Cardiac pulse waveform measurement device, portable device, medical device system, and vital sign information communication system
CN107088071A (en) * 2016-02-17 2017-08-25 松下知识产权经营株式会社 Bioinformation detecting device

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108852307A (en) * 2018-05-24 2018-11-23 重庆理工大学 A kind of non-contact noninvasive Arteriosclerosis detecting device
CN110881967A (en) * 2018-09-10 2020-03-17 深圳市迈迪优科技有限公司 Non-invasive multi-segment peripheral arterial vessel elastic function detection method and instrument thereof
CN109730723B (en) * 2019-03-11 2021-01-26 京东方科技集团股份有限公司 Method for determining pulse transmission time, arteriosclerosis detection equipment and system
CN109730723A (en) * 2019-03-11 2019-05-10 京东方科技集团股份有限公司 Determine method, artery sclerosis detection device and the system of pulse transit time
CN110710960A (en) * 2019-09-12 2020-01-21 东莞市康助医疗科技有限公司 Arterial blood vessel age estimation method and device
CN110710960B (en) * 2019-09-12 2022-12-09 东莞市康助医疗科技有限公司 Arterial blood vessel age estimation method and device
CN110960199A (en) * 2019-12-24 2020-04-07 中国人民解放军陆军军医大学第一附属医院 System for double-variable measurement of arteriosclerosis degree
CN111000537A (en) * 2019-12-24 2020-04-14 中国人民解放军陆军军医大学第一附属医院 Method for correcting influence of age, sex and blood pressure on pulse wave propagation speed
CN113303774A (en) * 2020-02-26 2021-08-27 Oppo广东移动通信有限公司 Wearable equipment
CN112274120A (en) * 2020-10-28 2021-01-29 河北工业大学 Noninvasive arteriosclerosis detection method and device based on one-way pulse wave
CN112274121A (en) * 2020-10-28 2021-01-29 河北工业大学 Noninvasive arteriosclerosis detection method and device based on multipath pulse waves
CN113229787A (en) * 2021-03-22 2021-08-10 安庆师范大学 Blood vessel age estimation and effectiveness evaluation method based on pulse signal shape characteristics
US11863937B2 (en) 2021-03-30 2024-01-02 Sonova Ag Binaural hearing system for providing sensor data indicative of a physiological property, and method of its operation
CN113598724A (en) * 2021-09-03 2021-11-05 上海市高血压研究所 Device for assessing cardiovascular autonomic nerve function

Similar Documents

Publication Publication Date Title
CN107961001A (en) Appraisal procedure, device and the atherosclerosis detector of Degree of arteriosclerosis
CN106413534B (en) Continuous blood pressure measuring device, measuring model establishing method and system
CN108185996B (en) Arterial blood vessel age estimation model construction method and device
CN104382571B (en) A kind of measurement blood pressure method and device based on radial artery pulse wave conduction time
US20170202459A1 (en) Wireless monitoring system
CN108186000A (en) Real-time blood pressure monitor system and method based on heart impact signal and photosignal
EP3474749B1 (en) Dynamic calibration of a blood pressure measurement device
JP6310401B2 (en) Method, system and computer program for processing a signal representing a physiological rhythm
EP3133985B1 (en) A method and a device for non invasive blood pressure measurement
CN109645979A (en) Ambulatory ecg signal artifact identification method and device
Hong et al. Aging index using photoplethysmography for a healthcare device: comparison with brachial-ankle pulse wave velocity
JP2017533034A (en) Actigraphy method and apparatus
CN103989463A (en) Radial artery pulse wave detecting system and method based on finger tip pulse waves
CN110115583A (en) The method and apparatus of monitoring of respiration
Rasool et al. Continuous and noninvasive blood pressure estimation by two-sensor measurement of pulse transit time
TWM554775U (en) Wireless position-detection blood pressure continuous measurement system
C. Dela Cruz et al. Deriving heart rate and respiratory rate from ecg using wavelet transform
EP3856014A1 (en) Model-based sensor technology for detection of cardiovascular status
Kotzen et al. Benchmarking photoplethysmography peak detection algorithms using the electrocardiogram signal as a reference
US20190298190A1 (en) Pulse detection, measurement and analysis based health management system, method and apparatus
CN104027097A (en) Vascular function noninvasive detecting method and device
Shoeibi et al. Nonlinear features of photoplethysmography signals for Non-invasive blood pressure estimation
C. Dela Cruz et al. Non-contact determination of heart rate variability using 24 GHz Doppler radar
Wolling et al. Optimal preprocessing of raw signals from reflective mode photoplethysmography in wearable devices
WO2020133497A1 (en) Method for evaluating recovery status of hospital patient, device, system, and storage medium

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20180427