CN107928845A - A kind of braided blood vessel stent and preparation method - Google Patents
A kind of braided blood vessel stent and preparation method Download PDFInfo
- Publication number
- CN107928845A CN107928845A CN201711261298.1A CN201711261298A CN107928845A CN 107928845 A CN107928845 A CN 107928845A CN 201711261298 A CN201711261298 A CN 201711261298A CN 107928845 A CN107928845 A CN 107928845A
- Authority
- CN
- China
- Prior art keywords
- alloy wire
- nitinol alloy
- blood vessel
- passivation film
- vessel stent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
Landscapes
- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a kind of braided blood vessel stent and preparation method, using braider using be enclosed with passivation film and drug-carried coat polyester multifilament, heat treatment after and be enclosed with the nitinol alloy wire of passivation film and drug-carried coat as raw material Co-knit, form of presentation is 2/2 twill-weave weaving method, during braiding, two kinds of silks are interleaved with each other, and unidirectional knitting forming, stent intertwined point after shaping is less, soft and elastic is good, and Relative sliding, surfacing are not likely to produce between braided wires.
Description
Technical field
The invention belongs to medical instruments field, more particularly to a kind of braided blood vessel stent and preparation method.
Background technology
Braided blood vessel stent is widely used in the narrow treatment of body cavities, is generally formed by the braiding of multiply monofilament,
Mostly from swollen type.Existing braided blood vessel stent existing defects：Diamond weave is similar to plain weave, and interweave electric more, flexing point
It is more, so that more stiff；He Gelisi braidings are similar to 3/3 twill-weave, and intertwined point is few, and it is long therefore strongly relatively regular to float length
Weave low, voidage is larger, and Relative sliding is relatively also easy to produce between yarn.
The content of the invention
The purpose of the present invention is that to solve the above-mentioned problems and provides a kind of braided blood vessel stent and preparation method.
The present invention is achieved through the following technical solutions above-mentioned purpose：
A kind of braided blood vessel stent, including intravascular stent body；
The rack body is the tubular structure by nitinol alloy wire and polyester multifilament knitting forming, and tube wall is oblique for 2/2
Line institutional framework, mesh are rectangle, and each crosspoint is the variable inside and outside silk overlay structure of the angle of the crossing, the Nitinol
Silk and the polyester multifilament surface are both provided with passivation film, and passivation film outer surface is provided with drug-carried coat.
Preferably, a diameter of 0.2mm of the nitinol alloy wire.
Preferably, the model 600D/192F of the polyester multifilament.
Preferably, the bore of the rack body is 6mm, pipe outside diameter is 6.8~7.2mm, thickness of pipe wall for 0.4~
0.6mm。
A kind of preparation method of braided blood vessel stent, comprises the following steps that：
Sizing heat treatment is carried out to nitinol alloy wire, in heat treatment process, nitinol alloy wire is wrapped in threaded bar mould
Heat on tool and jointly, nitinol alloy wire stereotyped structure is helical form, and heat treatment temperature is 500~600 DEG C, heat treatment time
For 5min；
In nitinol alloy wire and polyester multifilament surface design passivation film, and it is provided with passivation film outer surface and carries medicine painting
Layer；
Using braider to be enclosed with after the polyester multifilament of passivation film and drug-carried coat, heat treatment and be enclosed with passivating film
The nitinol alloy wire of layer and drug-carried coat is raw material Co-knit, and form of presentation is 2/2 twill-weave weaving method, is being woven
Cheng Zhong, two kinds of silks are interleaved with each other, and unidirectional knitting forming, and final overall structure forms tubulose.
The beneficial effects of the present invention are：
In the present invention, the tube wall of intravascular stent is 2/2 twill net structure, and intertwined point is less, compliance and elasticity is more preferable,
Relative sliding is not likely to produce between braided wires, is unidirectional weaving manner, surface more smooth.
Brief description of the drawings
Fig. 1 is the part frame wall schematic diagram of braided blood vessel stent of the present invention；
Fig. 2 is the cross-sectional view of polyester multifilament of the present invention；
Fig. 3 is the cross-sectional view of nitinol alloy wire of the present invention；
In figure：1- polyester multifilaments, 2- nitinol alloy wires, 3- crosspoints, 4- passivation films, 5- drug-carried coats.
Embodiment
The invention will be further described below in conjunction with the accompanying drawings：
With reference to shown in Fig. 1, Fig. 2 and Fig. 3, the present invention includes rack body, and rack body is by nitinol alloy wire 2 and terylene
The tubular structure of 1 knitting forming of multifilament, and tube wall is 2/2 twill-weave structure, mesh is rectangle, and each crosspoint 3 is
The variable inside and outside silk overlay structure of the angle of the crossing, nitinol alloy wire 2 and 1 surface of polyester multifilament are both provided with passivation film 4, and blunt
Change 4 outer surface of film layer and be provided with drug-carried coat 5.
Preferably, a diameter of 0.2mm of nitinol alloy wire 2.
Preferably, the model 600D/192F of polyester multifilament 1.
Preferably, the bore of rack body is 6mm, pipe outside diameter is 6.8~7.2mm, thickness of pipe wall for 0.4~
0.6mm。
The preparation method of braided blood vessel stent is as follows：
Sizing heat treatment is carried out to nitinol alloy wire 2, in heat treatment process, nitinol alloy wire 2 is wrapped in threaded bar
Heat on mould and jointly, 2 stereotyped structure of nitinol alloy wire is helical form, and heat treatment temperature is 500~600 DEG C, during heat treatment
Between be 5min；
In nitinol alloy wire and polyester multifilament surface design passivation film 4, and passivation film outer surface is provided with load medicine
Coating 5；
Using braider be enclosed with the polyester multifilament 1 of passivation film 4 and drug-carried coat 5, heat treatment after and be enclosed with blunt
The nitinol alloy wire 2 for changing film layer 4 and drug-carried coat 5 is raw material Co-knit, and form of presentation is 2/2 twill-weave weaving method,
During braiding, two kinds of silks are interleaved with each other, and unidirectional knitting forming, and final overall structure forms tubulose.During braiding,
Yarn device is taken using two, one of them takes yarn device winding screw shape nitinol alloy wire 2, another takes yarn device winding polyester multifilament 1,
Then schematic structure weaving is pressed.
Braided blood vessel stent of the present invention carries out bi-component braiding using polyester multifilament 1 and nitinol alloy wire 2, utilizes volume
Knit structure design and be prepared for integrated weaved type intravascular stent；
Terylene and Nitinol are two kinds of common Manual blood vessel tectorial membrane bracket biomaterials.Terylene is the one of polyester fiber
Kind, mechanical property is good, and durability is good, and cost is low, has good biocompatibility and stability in organismic internal environment；Nickel
Titanium alloy good biocompatibility, and there is shape memory and super-elasticity at the same time.The intertwined point of 2/2 twill net structure is less,
Strength and stiffening degree are not so good as diamond weave, but relatively soft, and elasticity is preferably；
Using first thermal finalization nitinol alloy wire 2, the rear scheme for carrying out bi-component braiding all-in-one blood pipe holder, is prepared into
The good internal diameter of type is the tubular bracket of 6mm；
It can be obtained by varying the configuration (quantity and arrangement of polyester multifilament 1 and nitinol alloy wire 2) of yarn during braiding
Obtain the intravascular stent of different structure；
During braiding, woven using unidirectional molding mode, surface is more smooth.
The foregoing is merely a prefered embodiment of the invention, is not intended to limit the invention, it is all the present invention spirit and
All any modification, equivalent and improvement made within principle etc., should be included within the scope of the present invention.
Claims (5)
1. a kind of braided blood vessel stent, including intravascular stent body, it is characterised in that
The rack body is the tubular structure by nitinol alloy wire and polyester multifilament knitting forming, and tube wall is 2/2 twill group
Knit structure, mesh is rectangle, and each crosspoint is the variable inside and outside silk overlay structure of the angle of the crossing, the nitinol alloy wire and
The polyester multifilament surface is respectively provided with passivation film, and passivation film outer surface is designed with drug-carried coat.
2. braided blood vessel stent according to claim 1, it is characterised in that a diameter of 0.2mm of the nitinol alloy wire.
3. braided blood vessel stent according to claim 1, it is characterised in that the model 600D/ of the polyester multifilament
192F。
4. braided blood vessel stent according to claim 1, it is characterised in that the bore of the rack body is 6mm, pipe
Outside diameter is 6.8~7.2mm, and thickness of pipe wall is 0.4~0.6mm.
A kind of 5. preparation method of braided blood vessel stent, it is characterised in that including：
Thermal finalization processing is carried out to nitinol alloy wire, in heat treatment process, nitinol alloy wire is wrapped on threaded bar mould
And heat jointly, nitinol alloy wire stereotyped structure is helical form, and heat treatment temperature is 500~600 DEG C, and heat treatment time is
5min；
In nitinol alloy wire and polyester multifilament surface design passivation film, and passivation film outer surface is provided with drug-carried coat；
Using braider be enclosed with the polyester multifilament of passivation film and drug-carried coat, heat treatment after and be enclosed with passivation film and
The nitinol alloy wire of drug-carried coat is raw material Co-knit, and form of presentation is 2/2 twill-weave weaving method, in braiding process
In, two kinds of silks are interleaved with each other, and unidirectional knitting forming, and final overall structure forms tubulose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711261298.1A CN107928845A (en) | 2017-12-04 | 2017-12-04 | A kind of braided blood vessel stent and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711261298.1A CN107928845A (en) | 2017-12-04 | 2017-12-04 | A kind of braided blood vessel stent and preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107928845A true CN107928845A (en) | 2018-04-20 |
Family
ID=61947482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711261298.1A Pending CN107928845A (en) | 2017-12-04 | 2017-12-04 | A kind of braided blood vessel stent and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107928845A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025414A (en) * | 2019-04-16 | 2019-07-19 | 吉林大学中日联谊医院 | A kind of braided blood vessel stent and preparation method thereof |
| CN115153953A (en) * | 2022-09-08 | 2022-10-11 | 深圳市华和创微医疗科技有限公司 | Three-dimensional braided stent and manufacturing method |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102973341A (en) * | 2012-11-08 | 2013-03-20 | 先健科技(深圳)有限公司 | Braided self-expanding type tube cavity support and manufacturing method thereof |
| WO2014093780A2 (en) * | 2012-12-13 | 2014-06-19 | 480 Biomedical, Inc. | Stent with reinforced joints |
| US20140243992A1 (en) * | 2013-02-28 | 2014-08-28 | Boston Scientific Scimed, Inc. | Medical devices for use along the biliary and/or pancreatic tract |
| CN105105867A (en) * | 2015-07-16 | 2015-12-02 | 东华大学 | Integrally-molded woven blood vessel covered stent and preparation method thereof |
| CN205181542U (en) * | 2015-11-19 | 2016-04-27 | 有研亿金新材料有限公司 | Close support of netting of multilayer |
| CN106073957A (en) * | 2016-06-20 | 2016-11-09 | 常州乐奥医疗科技股份有限公司 | A kind of Novel weaved intravascular stent |
-
2017
- 2017-12-04 CN CN201711261298.1A patent/CN107928845A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102973341A (en) * | 2012-11-08 | 2013-03-20 | 先健科技(深圳)有限公司 | Braided self-expanding type tube cavity support and manufacturing method thereof |
| WO2014093780A2 (en) * | 2012-12-13 | 2014-06-19 | 480 Biomedical, Inc. | Stent with reinforced joints |
| US20140243992A1 (en) * | 2013-02-28 | 2014-08-28 | Boston Scientific Scimed, Inc. | Medical devices for use along the biliary and/or pancreatic tract |
| CN105105867A (en) * | 2015-07-16 | 2015-12-02 | 东华大学 | Integrally-molded woven blood vessel covered stent and preparation method thereof |
| CN205181542U (en) * | 2015-11-19 | 2016-04-27 | 有研亿金新材料有限公司 | Close support of netting of multilayer |
| CN106073957A (en) * | 2016-06-20 | 2016-11-09 | 常州乐奥医疗科技股份有限公司 | A kind of Novel weaved intravascular stent |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025414A (en) * | 2019-04-16 | 2019-07-19 | 吉林大学中日联谊医院 | A kind of braided blood vessel stent and preparation method thereof |
| CN110025414B (en) * | 2019-04-16 | 2021-07-20 | 吉林大学中日联谊医院 | Braided vascular stent and preparation method thereof |
| CN115153953A (en) * | 2022-09-08 | 2022-10-11 | 深圳市华和创微医疗科技有限公司 | Three-dimensional braided stent and manufacturing method |
| CN115153953B (en) * | 2022-09-08 | 2023-01-03 | 深圳市华和创微医疗科技有限公司 | Three-dimensional braided stent and manufacturing method |
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Application publication date: 20180420 |
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