CN107898749A - A kind of topical composition with skin-care effect and preparation method thereof - Google Patents

A kind of topical composition with skin-care effect and preparation method thereof Download PDF

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Publication number
CN107898749A
CN107898749A CN201711485557.9A CN201711485557A CN107898749A CN 107898749 A CN107898749 A CN 107898749A CN 201711485557 A CN201711485557 A CN 201711485557A CN 107898749 A CN107898749 A CN 107898749A
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parts
preparation
honey
propolis
fermentation
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CN107898749B (en
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杜红
孙继林
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Chengdu Auxiliary Biology Technology Co Ltd
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Chengdu Auxiliary Biology Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Zoology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention provides a kind of topical composition with skin-care effect and preparation method thereof, it is prepared by the raw material of following weight proportioning:5~15 parts of safflower, 20~40 parts of ginseng, 5~15 parts of rhodiola root, 10~30 parts of hymsleya amabilis, 10~30 parts of radix glycyrrhizae, 20~40 parts of Poria cocos, 10~30 parts of radix astragali, 10~30 parts of lanatechead saussurea herb with flower, 30~50 parts of propolis, 350~500 parts of honey.The results show, topical composition of the invention have whitening, nti-freckle, moisturizing, anti-acne, calm down the multi-efficiencies such as wrinkle and anti-aging, solve the problems, such as that existing skin care item effect is single, have a vast market application prospect at the same time.

Description

A kind of topical composition with skin-care effect and preparation method thereof
Technical field
The invention belongs to cosmetic field, and in particular to a kind of topical composition and its preparation side with skin-care effect Method.
Background technology
With the development of science and technology with the continuous improvement of living standards of the people, cosmetics are in people live in occupation of more Carry out more consequence.In recent years, the kind of cosmetics is on the increase, its feature is also increasingly stronger, while scientific and technological content It is higher and higher.One of the mainstream product of skin care item as cosmetics, has also obtained significant progress.
At present, the skin care item of in the market mainly have two kinds, and one kind is using chemical synthesis substance as main component, although effect Substantially, but the harmful components such as heavy metal or fluorescent powder may be contained, long-time service can produce skin certain side effect;It is another Kind is Chinese medicinal skin care product, and effect relaxes, and toxic side effect is small.
But the effect of current Chinese medicinal skin care product, is single, it is necessary to which flesh could be solved using the different skin care item of multiple efficacies at the same time Skin there are the problem of.Such as:CN107049838A discloses a kind of more by fragrant citrus essential oil, cinnamon essential oil, Rosa Damascana, red wine What phenol, alkanet extract, rhodiola root extract, PORIA ALBA, peach kernel, rhizoma typhonii formed only has effects that the facial mask of anti-wrinkle; CN107375155A disclose it is a kind of by lotus-seed-heart powder, blueberry extracting solution, chamomile extracting solution, asparagus juice, Siraitia grosvenorii, trehalose, What honeysuckle, radix glycyrrhizae, rose, FOLIUM ET RAMULUS COTINI, hairystalk loosestrife herb formed only has effects that the facial mask of replenishing water and preserving moisture;CN104922011A is disclosed It is a kind of by aloe, white lilac, lead a cow in vain, PORIA ALBA, gingko benevolence, bletilla, the root of Dahurain angelica, Rhizoma Atractylodis Macrocephalae, bird's nest, adlay, felwort, when Return, the facial treatment milk only with white-skinned face function of ginkgo composition.
Therefore, it is badly in need of a kind of skin care item with multi-efficiency now.
The content of the invention
The technical scheme is that provide a kind of topical composition with skin-care effect.Another technology of the present invention Scheme there is provided the preparation method and purposes of the topical composition.
The present invention provides a kind of topical composition with skin-care effect, it is prepared by the raw material of following weight proportioning Form:
5~15 parts of safflower, 20~40 parts of ginseng, 5~15 parts of rhodiola root, 10~30 parts of hymsleya amabilis, 10~30 parts of radix glycyrrhizae, Poria cocos 20~40 parts, 10~30 parts of radix astragali, 10~30 parts of lanatechead saussurea herb with flower, 30~50 parts of propolis, 350~500 parts of honey.
It is further preferred that it is prepared by the raw material of following weight proportioning:
10 parts of safflower, 30 parts of ginseng, 10 parts of rhodiola root, 20 parts of hymsleya amabilis, 20 parts of radix glycyrrhizae, 30 parts of Poria cocos, 20 parts of radix astragali, saussurea involucrata Spend 20 parts, 40 parts of propolis, 400 parts of honey.
The present composition be by safflower, ginseng, rhodiola root, hymsleya amabilis, radix glycyrrhizae, Poria cocos, radix astragali, lanatechead saussurea herb with flower primary powder End, water or extractive with organic solvent be active ingredient, in addition propolis, honey and medicine, cosmetics acceptable auxiliary material or The preparation that auxiliary sexual element is prepared.
Wherein, the preparation is emulsion, film, gelling agent.Specific product may include mildy wash, facial mask, lotion, face cream Or eye cream.
Present invention also offers the preparation method of the topical composition, it comprises the following steps:
(1) propolis and honey are weighed by weight ratio, is stirred evenly, under conditions of 25~40 DEG C of temperature, humidity 75% It is sealed by fermentation 1~3 day, up to propolis honey;
(2) by other raw materials, broken wall is ground into impalpable powder respectively;
(3) impalpable powder and propolis honey are weighed by weight ratio, is stirred evenly, in 25~30 DEG C of temperature, the bar of humidity 75% It is sealed by fermentation 5~15 days under part, adds the preparation that acceptable auxiliary material or auxiliary sexual element are prepared in medicine, cosmetics.
Wherein, in step (1), fermentation temperature is 30 DEG C, and fermentation time is 2 days.
Wherein, in step (2), the temperature of the broken wall is 10 ± 2 DEG C.
Wherein, in step (3), fermentation temperature is 25 DEG C, and fermentation time is 10 days.
Wherein, in step (3), fermentation process further includes stirring 10 minutes daily, and mixing speed is 20 revs/min;It is preferred that Ground, the stirring are stirring 5 minutes clockwise, counterclockwise stirring 5 minutes.
Present invention also offers the topical composition to prepare whitening, nti-freckle, moisturizing, anti-acne, calm down wrinkle or prolong Purposes in the medicine or cosmetics of slow aging.
In the present invention, safflower, invigorate blood circulation, removing blood stasis and analgesics;Ginseng, reinforces vital energy, and veins takes off admittedly, reinforces the spleen to benefit the lung, and promotes the production of body fluid Blood-nourishing, tranquilize the mind and promote the intelligence;Rhodiola root, qi and activate blood circulation, promotes blood circulation and relievings asthma;Hymsleya amabilis, clearing heat and detoxicating, swelling and pain relieving;Radix glycyrrhizae, invigorates the spleen and benefits qi, It is clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription;Poria cocos, clearing damp and promoting diuresis, invigorating the spleen, calming heart;Radix astragali, tonifying Qi and lifting yang, Gu Table hidroschesis, inducing diuresis for removing edema, blood-nourishing of promoting the production of body fluid, the stagnant logical numbness of row, pus draining and toxin expelling, expelling pus and promoting granulation;Lanatechead saussurea herb with flower, clearing heat and detoxicating, swelling and pain relieving; Propolis, qi-restoratives is weak, changes turbid fat, only quenches one's thirst, external application removing toxicity for detumescence, restrains myogenic;Honey, bowl spares, moisturizes, and relieves pain, removing toxic substances, external application Myogenic sore.
Topical composition of the present invention skilfully uses the Functions of all kinds of Chinese medicines each effect, at the same skilfully use pure natural honey, Propolis, does not add the pure natural skin care item of any additive.Skin care item of the present invention are played to greatest extent by fermentation, all kinds of Chinese medicines Respective effect, and during the fermentation, skin care item are finer and smoother, use and more moisten.
The results show, topical composition of the invention have at the same time whitening, nti-freckle, moisturizing, anti-acne, calm down wrinkle with And the multi-efficiency such as anti-aging, solve the problems, such as that existing skin care item effect is single, have a vast market application prospect.
Obviously, the above according to the present invention, according to the ordinary technical knowledge and customary means of this area, is not departing from Under the premise of the above-mentioned basic fundamental thought of the present invention, the modification, replacement or change of other diversified forms can also be made.
The embodiment of form by the following examples, remakes further specifically the above of the present invention It is bright.But the scope that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to following example.It is all to be based on the above of the present invention The technology realized belongs to the scope of the present invention.
Brief description of the drawings
Fig. 1 is the propolis honey after present invention fermentation.
Fig. 2 is the mixed broken wall traditional Chinese medicine powder of the present invention.
Fig. 3 is the paste mixture before present invention fermentation.
Fig. 4 is the facial mask of fermentation 2 days.
Fig. 5 is the facial mask after fermenting 10 days.
Embodiment
The preparation of embodiment 1, facial mask of the present invention
Formula:Safflower 10g, ginseng 30g, rhodiola root 10g, hymsleya amabilis 20g, radix glycyrrhizae 20g, Poria cocos 30g, radix astragali 20g, lanatechead saussurea herb with flower 20g, propolis 40g, honey 400g.
Preparation method:
1. weighing honey and propolis by formula ratio, stir evenly, be placed in 30 DEG C of temperature, sealed in the environment of humidity 75%, Fermentation 2 days, is made propolis honey, sees Fig. 1.
, except all raw materials of propolis honey are ground into impalpable powder respectively at broken wall at 10 DEG C, 2. 200 mesh will be crossed in formula Sieve, all raw material powder except propolis honey are weighed by formula ratio, are uniformly mixed, are seen Fig. 2.
3. adding the propolis honey fermented into mixed material powder, stir, paste is made, see Fig. 3.
4. by step, 3. middle gained paste is placed in 25 DEG C of temperature, is sealed in the environment of humidity 75%, stirring of uncapping daily Once, with 20 turns per minute of speed, stirring 5 minutes, then stirring 5 minutes clockwise counterclockwise, ferment 10 days, see Fig. 4, Fig. 5.
Application method:After abundant face cleaning, face is directly spread on, is cleaned after 20~30 minutes, 2~3 times weekly.
The preparation of embodiment 2, lotion of the present invention
Formula:Safflower 5g, ginseng 20g, rhodiola root 15g, hymsleya amabilis 10g, radix glycyrrhizae 30g, Poria cocos 20g, radix astragali 30g, lanatechead saussurea herb with flower 10g, propolis 50g, honey 350g.
Preparation method:
1. weighing honey and propolis by formula ratio, stir evenly, be placed in 30 DEG C of temperature, sealed in the environment of humidity 75%, Fermentation 2 days, is made propolis honey.
2. weighing all raw materials except propolis honey by formula ratio, the water of 10 times of amounts is added, decocts 30min, filtering, filter residue The water of 8 times of amounts is added, decocts 20min, filtering, merges filtrate twice, concentration.
3. adding propolis honey into concentrate, it is uniformly mixed, you can.
The preparation of embodiment 3, mildy wash of the present invention
Formula:Safflower 15g, ginseng 40g, rhodiola root 5g, hymsleya amabilis 30g, radix glycyrrhizae 10g, Poria cocos 40g, radix astragali 10g, lanatechead saussurea herb with flower 30g, propolis 30g, honey 500g.
Preparation method:
1. weighing honey and propolis by formula ratio, stir evenly, be placed in 30 DEG C of temperature, sealed in the environment of humidity 75%, Fermentation 2 days, is made propolis honey.
2. all raw materials of propolis honey will be removed in formula, impalpable powder is ground into respectively at broken wall at 10 DEG C, crosses 200 mesh Sieve, all raw materials except propolis honey are weighed by formula ratio, are uniformly mixed.
3. by above-mentioned raw materials powder, propolis honey and 2g laureth sodium sulfovinates, it is uniformly mixed, you can.
The screening of embodiment 4, facial mask fermentation condition of the present invention
1st, the screening of fermentation temperature
Using the formula and preparation method of embodiment 1, influence of the fermentation temperature to facial mask lotion in investigating step 4., Range of temperature is 20~30 DEG C, and experimental result is as shown in table 1:
Table 1, facial mask lotion fermentation temperature screening
2nd, the screening for humidity of fermenting
Using the formula and preparation method of embodiment 1, influence of the fermentation humidity to facial mask lotion in investigating step 4., Range of humidity variation is 60%~90%, and experimental result is as shown in table 2:
The screening of table 2, facial mask lotion fermentation humidity
3rd, the screening of fermentation time
Using the formula and preparation method of embodiment 1, influence of the fermentation time to facial mask lotion in investigating step 4., Time change scope is 1~15 day, and experimental result is as shown in table 3:
The screening of table 3, facial mask lotion fermentation time
Test result indicates that the optimal fermentation temperature of facial mask lotion of the present invention is 30 DEG C, fermentation humidity is 75%, during fermentation Between be 10 days.
Illustrate beneficial effects of the present invention below by way of the mode of test example.
Test example 1
1st, test material
The facial mask that embodiment 1 is prepared;New seven white whitening and softening skin facial mask (shining new edition) of herborist (make up by Shanghai herborist Product Co., Ltd) contain " new seven is white " upgrading elite that seven kinds of Chinese herbal medicines such as Radix Paeoniae Alba, radix ampelopsis, the bletilla striata, tribulus terrestris gather.
2nd, test object
45 volunteers, women, 22~60 years old age, 15 one group of people.
3rd, test method and result
3.1 test method:
The female volunteers 45 at 22~60 years old age are selected during test, are randomly divided into test group, positive controls, sky White 3 groups of control group, every group of 15 people.The facial mask that test group volunteer is prepared using embodiment 1, positive controls volunteer make With new seven white whitening and softening skin facial mask (shining new edition) of herborist, blank control group volunteer is without using any product, test group and sun Property control group according to the respective application method normal use of facial mask, test period is 1 month.Observe each group volunteer before testing With changed corresponding number after test.
3.2 testing standards and result
3.2.1 moisturizing is tested
Testing standard:The easy peeling of skin, tight person are drying, and face moistens, flexible person is moistening, between the two for Normally.Test result is shown in Table 4.
4 moisturizing of table is tested
Test result indicates that compared with blank control group, test group has obvious moistening effect, with positive controls ratio Compared with test group moistening effect is better than positive controls.
3.2.2 whitening is tested
Testing standard:Using the facial mask front-back portion colour of skin occur change, after use compared with before use, blee highlight, No longer dark yellow person is then to bleach.Test result is shown in Table 5.
5 whitening of table is tested
Test result indicates that compared with blank control group, test group has obvious whitening effect, with positive controls ratio Compared with test group whitening effect is better than positive controls.
3.2.3 light spot test
Testing standard:For the crowd of the existing spot of face, the change occurred using facial mask front-back portion spot, is relatively made after use Desalinated with preceding, facial spot or even disappeared.Test result is shown in Table 6.
6 light spot of table is tested
Group There is spot number before test Light spot number after test
Test group 6 4
Positive controls 5 1
Blank control group 8 0
Test result indicates that compared with blank control group, test group has obvious light spot effect, with positive controls ratio Compared with the light spot effect of test group is better than positive controls.
3.2.4 anti-acne is tested
Testing standard:For the crowd of the long acne of face, the change occurred using the acne in facial mask front-back portion, after use compared with Before use, the acne of face has decreased or even eliminated.Test result is shown in Table 7.
7 anti-acne of table is tested
Group There is acne number before test Anti-acne number after test
Test group 5 5
Positive controls 6 0
Blank control group 3 0
Test result indicates that compared with blank control group, test group has obvious anti-acne effect, with positive controls ratio Compared with test group anti-acne effect is better than positive controls.
3.2.5 anti-wrinkle is tested
Testing standard:For the crowd of the long wrinkle of face, the change occurred using facial mask front-back portion wrinkle, after use Compared with before use, the wrinkle of face has been lessened or even eliminated.Test result is shown in Table 8.
8 anti-wrinkle of table is tested
Group There is wrinkle number before test Anti-wrinkle number after test
Test group 3 2
Positive controls 2 0
Blank control group 3 0
Test result indicates that compared with blank control group, positive controls, test group has obvious anti-wrinkle effect.
To sum up, the present invention plays respective effect by skilfully using the functions of all kinds of Chinese medicines, at the same skilfully use pure natural honey, Propolis, the pure natural skin care item for not containing any additive being prepared have whitening, nti-freckle, moisturizing, anti-acne, calm down at the same time The multi-efficiency such as wrinkle and anti-aging, solves the problems, such as that existing skin care item effect is single, has a vast market application Prospect.

Claims (10)

  1. A kind of 1. topical composition with skin-care effect, it is characterised in that:It is by following weight proportioning raw material prepare and Into:
    5~15 parts of safflower, 20~40 parts of ginseng, 5~15 parts of rhodiola root, 10~30 parts of hymsleya amabilis, 10~30 parts of radix glycyrrhizae, Poria cocos 20~ 40 parts, 10~30 parts of radix astragali, 10~30 parts of lanatechead saussurea herb with flower, 30~50 parts of propolis, 350~500 parts of honey.
  2. 2. topical composition according to claim 1, it is characterised in that:It is by following weight proportioning raw material prepare and Into:
    10 parts of safflower, 30 parts of ginseng, 10 parts of rhodiola root, 20 parts of hymsleya amabilis, 20 parts of radix glycyrrhizae, 30 parts of Poria cocos, 20 parts of radix astragali, lanatechead saussurea herb with flower 20 Part, 40 parts of propolis, 400 parts of honey.
  3. 3. topical composition according to claim 1 or 2, it is characterised in that:It is by safflower, ginseng, rhodiola root, snow Courage, radix glycyrrhizae, Poria cocos, radix astragali, primary powder, water or the extractive with organic solvent of lanatechead saussurea herb with flower are active ingredient, add propolis, honey And the preparation that acceptable auxiliary material or auxiliary sexual element are prepared in medicine, cosmetics.
  4. 4. topical composition according to claim 3, it is characterised in that:The preparation is emulsion, film, gelling agent.
  5. 5. the preparation method of any one of the claim 1-4 topical compositions, it is characterised in that:It comprises the following steps:
    (1) propolis and honey are weighed by weight ratio, is stirred evenly, and are sealed under conditions of 25~40 DEG C of temperature, humidity 75% Fermentation 1~3 day, up to propolis honey;
    (2) by other raw materials, broken wall is ground into impalpable powder respectively;
    (3) impalpable powder and propolis honey are weighed by weight ratio, is stirred evenly, under conditions of 25~30 DEG C of temperature, humidity 75% It is sealed by fermentation 5~15 days, adds the preparation that acceptable auxiliary material or auxiliary sexual element are prepared in medicine, cosmetics.
  6. 6. preparation method according to claim 5, it is characterised in that:In step (1), fermentation temperature is 30 DEG C, during fermentation Between be 2 days.
  7. 7. the preparation method according to claim 5 or 6, it is characterised in that:In step (2), the temperature of the broken wall is 10 ±2℃。
  8. 8. preparation method according to claim 5, it is characterised in that:In step (3), fermentation temperature is 25 DEG C, during fermentation Between be 10 days.
  9. 9. preparation method according to claim 5, it is characterised in that:In step (3), fermentation process further includes daily stirring 10 minutes, mixing speed was 20 revs/min;Preferably, the stirring is stirring 5 minutes clockwise, counterclockwise stirring 5 minutes.
  10. 10. preparing whitening, nti-freckle according to claim 1-4 any one of them topical composition, moisturizing, anti-acne, calming down wrinkle Purposes in line or the medicine or cosmetics of anti-aging.
CN201711485557.9A 2017-12-29 2017-12-29 A topical composition with skin caring effect and its preparation method Active CN107898749B (en)

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CN115804741A (en) * 2022-12-10 2023-03-17 广州腾麟生物科技有限公司 Anti-aging active composition for promoting absorption and preparation method and application thereof

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CN115177576A (en) * 2022-09-09 2022-10-14 广州优理氏生物科技有限公司 Composition for moisturizing, repairing and anti-aging of skin, application of composition and facial mask liquid
CN115804741A (en) * 2022-12-10 2023-03-17 广州腾麟生物科技有限公司 Anti-aging active composition for promoting absorption and preparation method and application thereof

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Application publication date: 20180413

Assignee: SICHUAN FUZHENG PHARMACEUTICAL CO.,LTD.

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