CN107898650A - Antibacterial soft liner materials for denture - Google Patents

Antibacterial soft liner materials for denture Download PDF

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Publication number
CN107898650A
CN107898650A CN201711380942.7A CN201711380942A CN107898650A CN 107898650 A CN107898650 A CN 107898650A CN 201711380942 A CN201711380942 A CN 201711380942A CN 107898650 A CN107898650 A CN 107898650A
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CN
China
Prior art keywords
glue
holly
parts
olive
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711380942.7A
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Chinese (zh)
Inventor
陈国平
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JIANGSU PROVINCE JIAN'ERKANG PHARMACEUTICAL SURGICAL DRESSING CO Ltd
Original Assignee
JIANGSU PROVINCE JIAN'ERKANG PHARMACEUTICAL SURGICAL DRESSING CO Ltd
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Application filed by JIANGSU PROVINCE JIAN'ERKANG PHARMACEUTICAL SURGICAL DRESSING CO Ltd filed Critical JIANGSU PROVINCE JIAN'ERKANG PHARMACEUTICAL SURGICAL DRESSING CO Ltd
Priority to CN201711380942.7A priority Critical patent/CN107898650A/en
Publication of CN107898650A publication Critical patent/CN107898650A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/80Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/884Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
    • A61K6/887Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/30Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
    • A61K6/35Preparations for stabilising dentures in the mouth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/80Preparations for artificial teeth, for filling teeth or for capping teeth

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  • Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Dental Preparations (AREA)

Abstract

The present invention relates to soft liner materials for denture technical field, especially a kind of soft its mass parts composition of antibacterial artificial tooth is as follows:80 100 parts of rubber mass, 1.2 2.8 parts of vulcanizing activator, 0.8 3.2 parts of stearic acid, 0.2 0.8 parts of magnesia, 0.1 0.9 parts of vitamin E;The rubber mass is made of holly glue, olive glue and butadiene rubber, and the mass ratio of holly glue, olive glue and butadiene rubber is 10:1‑1.8:5;Rubber mass is made in holly glue, olive glue and butadiene rubber in the present invention, improves sterilization, the bacteriostasis efficacy of rubber mass, helps to protect gum, improves oral health;The preparation method of holly glue and olive glue is simple and environmentally-friendly pollution-free in the present invention, and obtained product health is harmless, improves safety in utilization.

Description

Antibacterial soft liner materials for denture
Technical field
The present invention relates to soft liner materials for denture technical field, especially a kind of antibacterial soft liner materials for denture.
Background technology
Soft liner materials for denture, also known as flexible denture gasket material, can utilize its elastic deformation buffering snap-in force, close artificial tooth Tissue surface and tooth grain mucosal contact relation, and improve denture retention using tissue undercut area, it is that clinically common alleviate lives The important measures for the symptoms such as Malretention that dynamic artificial tooth occurs during wearing, repeatedly tenderness, masticatory efficiency be low.Can as one kind Long-time service and the material contacted with oral mucosa surface, the stability of its performance and the disease of cari oris mucosa easily triggered are limitations Its principal element applied.The relation that soft liner materials for denture occurs with denture stomatitis, is the major issue of clinician's concern, And the key for causing denture stomatitis to occur is adhesion of the microorganism especially Candida albicans to soft lining material.Therefore, research and develop It is a kind of to keep stablizing under physiological status, there is bonds well performance and be resistant to the denture soft lining material of candida albicans infection Material, has important clinical meaning.
The content of the invention
The purpose of the present invention is:A kind of stabilization under physiological status is provided, there is good adhesive property and be resistant to white The soft liner materials for denture of monilial infection.
In order to solve the above technical problems, the technical solution adopted by the present invention is as follows:
A kind of antibacterial soft liner materials for denture, its mass parts composition are as follows:80-100 parts of rubber mass, vulcanizing activator 1.2- 2.8 parts, 0.8-3.2 parts of stearic acid, 0.2-0.8 parts of magnesia, 0.1-0.9 parts of vitamin E;
The rubber mass is made of holly glue, olive glue and butadiene rubber, the matter of holly glue, olive glue and butadiene rubber Amount is than being 10:1-1.8:5.
Preferably, the antibacterial soft liner materials for denture is handled using the mixed solution of seaweed and dietary alkali, in mixed solution The mass fraction of seaweed is 20%, and the mass fraction of dietary alkali is 30%.
Preferably, the holly glue is made using following methods:By leaf of Chinese ilex spontaneous fermentation 15-18d, by ripe Chinese ilex Fruit is mixed in a certain ratio with the leaf of Chinese ilex to ferment, adds water infusion, after filtering, it is 1.1g/cm that filtrate, which is endured to concentration,3, obtain the winter Blue or green glue.
Preferably, the olive glue is made using following methods:By olive fruit spontaneous fermentation 15-18d, remove dento liva, Add water infusion, after filtering, it is 1.1g/cm that filtrate, which is endured to concentration,3, obtain olive glue.
Preferably, the mass ratio of the holly glue, olive glue and butadiene rubber is 10:1.5:5.
The beneficial effect of technical solution using the present invention is:
1st, rubber mass is made in holly glue, olive glue and butadiene rubber in the present invention, improves sterilization, the suppression of rubber mass Bacterium effect, helps to protect gum, improves oral health.
2nd, the preparation method of holly glue and olive glue is simple and environmentally-friendly pollution-free in the present invention, and obtained product health is harmless, Improve safety in utilization.
Embodiment
With reference to embodiment, the invention will be further described.
Embodiment 1
A kind of antibacterial soft liner materials for denture, its mass parts composition are as follows:It is 80 parts of rubber mass, 1.2 parts of vulcanizing activator, hard 0.8 part of resin acid, 0.2 part of magnesia, 0.1 part of vitamin E;Rubber mass is made of holly glue, olive glue and butadiene rubber, Chinese ilex The mass ratio of glue, olive glue and butadiene rubber is 10:1:5, holly glue is made using following methods in the present embodiment:By leaf of Chinese ilex Spontaneous fermentation 15d, ripe holly berry is mixed in a certain ratio with the leaf of Chinese ilex to ferment, adds water infusion, after filtering, filtrate is endured It is 1.1g/cm to concentration3, obtain holly glue.
Olive glue is made using following methods in the present embodiment:By olive fruit spontaneous fermentation 15d, remove dento liva, add water Infusion, after filtering, it is 1.1g/cm that filtrate, which is endured to concentration,3, obtain olive glue.
Antibacterial soft liner materials for denture is handled using the mixed solution of seaweed and dietary alkali in the present embodiment, sea in mixed solution The mass fraction of algae is 20%, and the mass fraction of dietary alkali is 30%.
Embodiment 2
A kind of antibacterial soft liner materials for denture, its mass parts composition are as follows:90 parts of rubber mass, 2 parts of vulcanizing activator, tristearin 2 parts of acid, 0.5 part of magnesia, 0.5 part of vitamin E;Rubber mass is made of holly glue, olive glue and butadiene rubber, holly glue, The mass ratio of olive glue and butadiene rubber is 10:1.5:5, holly glue is made using following methods in the present embodiment:By leaf of Chinese ilex Spontaneous fermentation 16d, ripe holly berry is mixed in a certain ratio with the leaf of Chinese ilex to ferment, adds water infusion, after filtering, filtrate is endured It is 1.1g/cm to concentration3, obtain holly glue.
Olive glue is made using following methods in the present embodiment:By olive fruit spontaneous fermentation 16d, remove dento liva, add water Infusion, after filtering, it is 1.1g/cm that filtrate, which is endured to concentration,3, obtain olive glue.
Antibacterial soft liner materials for denture is handled using the mixed solution of seaweed and dietary alkali in the present embodiment, sea in mixed solution The mass fraction of algae is 20%, and the mass fraction of dietary alkali is 30%.
Embodiment 3
A kind of antibacterial soft liner materials for denture, its mass parts composition are as follows:100 parts of rubber mass, 2.8 parts of vulcanizing activator, 3.2 parts of stearic acid, 0.8 part of magnesia, 0.9 part of vitamin E;The rubber mass is by holly glue, olive glue and butadiene rubber group Into the mass ratio of holly glue, olive glue and butadiene rubber is 10:1.8:5, holly glue uses following methods system in the present embodiment :By leaf of Chinese ilex spontaneous fermentation 18d, ripe holly berry is mixed in a certain ratio with the leaf of Chinese ilex to ferment, adds water infusion, mistake After filter, it is 1.1g/cm that filtrate, which is endured to concentration,3, obtain holly glue.
Olive glue is made using following methods in the present embodiment:By olive fruit spontaneous fermentation 18d, remove dento liva, add water Infusion, after filtering, it is 1.1g/cm that filtrate, which is endured to concentration,3, obtain olive glue.
Antibacterial soft liner materials for denture is handled using the mixed solution of seaweed and dietary alkali in the present embodiment, sea in mixed solution The mass fraction of algae is 20%, and the mass fraction of dietary alkali is 30%.
Antibacterial soft liner materials for denture in embodiment 1-3 is made using common preparation method.
Water imbibition, dissolubility test, in this experiment, Wo Menxuan are carried out to the antibacterial soft liner materials for denture in the present invention Selecting two kinds, clinically common acrylic resin and silastic material are as reference object, respectively in distilled water and artificial saliva Place 7-30 days in two media, contrasted with the material of the present invention (in embodiment 2).
(1) preparation of artificial saliva
The formula of artificial saliva is as shown in table 1, adds 1l distilled water, adjusts pH to 7.0, manually work saliva is put after configuration completion Enter and be mixed evenly in 37 DEG C of waters bath with thermostatic control, it is spare.
Table 1
Component Content mg/l
Potassium chloride 11200
Sodium chloride 6700
Disodium hydrogen phosphate 260
Potassium dihydrogen phosphate 200
Saleratus 1500
Potassium rhodanate 330
(2) specific experiment:
The sample prepared is cleaned by ultrasonic 10min by a in distilled water, is then disappeared under the conditions of 3 atmospheric pressure, 121 DEG C Malicious 20min, is then placed in 30 DEG C of drier and stores 24h, after move in the drier of room temperature and store 30min, then weigh, Record weight m1
Each group sample is put into 37 DEG C of distilled water and artificial saliva stores 30d respectively by b, then respectively by sample from water Middle taking-up, is gently done solid work macroscopic water stain with blotting paper, dries 15s in atmosphere, when taking out 1min or so in water, is claimed Weight, record weight m2
Sample is placed again into drier by c, when quality is constant again, records weight m3
Sample water absorption rate and dissolution rate are calculated respectively;
The water absorption rate and meltage of the present invention meets regulation.
It is complete by above-mentioned description, relevant staff using the above-mentioned desirable embodiment according to the present invention as enlightenment Various changes and amendments can be carried out without departing from the scope of the technological thought of the present invention' entirely.The technology of this invention Property scope is not limited to the content on specification, it is necessary to determines its technical scope according to right.

Claims (5)

1. a kind of antibacterial soft liner materials for denture, it is characterised in that its mass parts composition is as follows:80-100 parts of rubber mass, vulcanization 1.2-2.8 parts of activating agent, 0.8-3.2 parts of stearic acid, 0.2-0.8 parts of magnesia, 0.1-0.9 parts of vitamin E;
The rubber mass is made of holly glue, olive glue and butadiene rubber, the mass ratio of holly glue, olive glue and butadiene rubber For 10:1-1.8:5.
2. antibacterial soft liner materials for denture according to claim 1, it is characterised in that:The antibacterial soft liner materials for denture uses The mixed solution of seaweed and dietary alkali is handled, and the mass fraction of seaweed is 20% in mixed solution, and the mass fraction of dietary alkali is 30%.
3. antibacterial soft liner materials for denture according to claim 1, it is characterised in that:The holly glue uses following methods system :By leaf of Chinese ilex spontaneous fermentation 15-18d, ripe holly berry is mixed in a certain ratio with the leaf of Chinese ilex to ferment, adds water to endure Boil, after filtering, it is 1.1g/cm that filtrate, which is endured to concentration,3, obtain holly glue.
4. antibacterial soft liner materials for denture according to claim 1, it is characterised in that:The olive glue uses following methods system :By olive fruit spontaneous fermentation 15-18d, remove dento liva, add water infusion, after filtering, it is 1.1g/cm that filtrate, which is endured to concentration,3, Obtain olive glue.
5. antibacterial soft liner materials for denture according to claim 1, it is characterised in that:The holly glue, olive glue and suitable fourth The mass ratio of rubber is 10:1.5:5.
CN201711380942.7A 2017-12-20 2017-12-20 Antibacterial soft liner materials for denture Pending CN107898650A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108743402A (en) * 2018-06-25 2018-11-06 周以水 A kind of Anticmicrobial denture soft lining material and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1611194A (en) * 2003-12-29 2005-05-04 郭立明 Artificial tooth base soft pad and its preparing method
CN101125999A (en) * 2007-09-30 2008-02-20 川渝中烟工业公司 Method for extracting holly glue
JP2013249297A (en) * 2012-06-04 2013-12-12 Tokuyama Dental Corp Adhesive for denture base lining material
CN104546505A (en) * 2014-11-24 2015-04-29 中南大学湘雅二医院 Antibacterial false tooth soft lining material and application thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1611194A (en) * 2003-12-29 2005-05-04 郭立明 Artificial tooth base soft pad and its preparing method
CN101125999A (en) * 2007-09-30 2008-02-20 川渝中烟工业公司 Method for extracting holly glue
JP2013249297A (en) * 2012-06-04 2013-12-12 Tokuyama Dental Corp Adhesive for denture base lining material
CN104546505A (en) * 2014-11-24 2015-04-29 中南大学湘雅二医院 Antibacterial false tooth soft lining material and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王建新: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108743402A (en) * 2018-06-25 2018-11-06 周以水 A kind of Anticmicrobial denture soft lining material and preparation method thereof

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Address after: No.1 jianerkang Road, Zhixi Town, Jintan District, Changzhou City, Jiangsu Province

Applicant after: Jianerkang Medical Technology Co.,Ltd.

Address before: No.1 jianerkang Road, Zhixi Town, Jintan District, Changzhou City, Jiangsu Province

Applicant before: Jiangsu jianerkang Medical Technology Co.,Ltd.

Address after: No.1 jianerkang Road, Zhixi Town, Jintan District, Changzhou City, Jiangsu Province

Applicant after: Jiangsu jianerkang Medical Technology Co.,Ltd.

Address before: No.1 jianerkang Road, Zhixi Town, Jintan District, Changzhou City, Jiangsu Province

Applicant before: JIANGSU PROVINCE JIANERKANG MADICAL DRESSING CO.,LTD.

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Application publication date: 20180413