CN107875198A - A kind of Chinese medicine composition for treating syphilis and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating syphilis and preparation method thereof Download PDFInfo
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- CN107875198A CN107875198A CN201711133551.5A CN201711133551A CN107875198A CN 107875198 A CN107875198 A CN 107875198A CN 201711133551 A CN201711133551 A CN 201711133551A CN 107875198 A CN107875198 A CN 107875198A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The present invention relates to a kind of Chinese medicine composition for treating syphilis and preparation method thereof.The Chinese medicine is prepared by the raw material including following parts by weight：Phoenix tree root, beggar-ticks, climbing groundsel, baeckea frutescen leaf, castor leaf.Present invention also offers the preparation method of this Chinese medicine composition.Chinese medicine composition provided by the invention is curative for effect, security is good, is free from side effects in treatment one, in terms of mesosyphilis, and it is easy to use, cost is low, effect is better than prior art.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition for treating syphilis and preparation method thereof.
Background technology
Modern medicine thinks that syphilis is as caused by syphilization conveyor screw, and rotten to the corn with private parts, outer breakout, muscles and bones is ached
Bitterly, skin nuclei of origin and fester, the dull-witted infectious disease mainly to show of look.The overwhelming majority is by sex track transmission, is a kind of
Sexually transmitted disease.It clinically can behave as primary syphilis, mesosyphilis, tertiary syphilis and latent syphilis.Simultaneously again have it is congenital and
Point of the day after tomorrow.Congenital mainly congenital syphilis, i.e. mother suffer from syphilis, fetus also syphilization.The day after tomorrow is due to unclean property more
Life causes.Primary syphilis:Significant Clinical symptoms is chancre.Secondary syphilid is characterized, and has constitutional symptom, chancre
Generation or overlapping generation after regression.The mucocutaneous damage subcutaneous fibrotic tubercle evil syphilitic heart disease of tertiary syphilis also has neural plum
Poison.Treatment of the modern medicine to syphilis has the effect of very big.
Syphilis is referred to as syphilis in the traditional Chinese medical science, mould sore, wide sore, day willow disease, venereal disease, sells sore, mycotic ulcer caused by venereal disease etc..It is rotten with private parts
It is rotten, outer breakout, arthralgia and myalgia, skin nuclei of origin and fester, the dull-witted epidemic disease class disease waited as common manifestation of look《Continuous doctor says》
Carry：It is great to control（1488 1505）It is the last years of a dynasty or reign, among the people to suffer from malignant sore, fail to see, exhaled as wide sore from Cantonese beginning Wu people.It is similar to again with it, meaning
Syphilis.《Compendium of Materia Medica》Author, famous medical scholar's Li Shizhen (1518-1593 A.D.) speaks approvingly of：Syphilis, ancient prescription do not carry, also without patient.
The south of the Five Ridges is arised from when near, is passed and cubic.It can be seen that in China, syphilis is a kind of thing from abroad, by Guangdong import throughout various regions.
The etiology and pathogenesis of syphilis causes for damp and hot pathogenic fire detoxification.《Surgery orthodox school syphilis opinion the 36th》Middle proposition：
" husband syphilis person, red bayberry is similar to it；Also known as when sore, because when gas multiply change, perverse trend, which is gathered, attacks；Also known as continuous flower sore, from phase continuous difficulty
Absolutely.There is the title of this three, always by the change of damp and hot pathogenic fire "《It is concise to cure syphilis of drawing a bow to the full》Middle theory：" this sore be toxic dampness and heat institute into.”
（1）Primary syphilis：Primary syphilis, the traditional Chinese medical science are referred to as chancre.
[rules for the treatment of] purging liver-heat, dampness removing toxic removing
（2）Mesosyphilis：Mesosyphilis, the traditional Chinese medical science are referred to as syphilis, are named because of its color such as red bayberry.Therefore, the traditional Chinese medical science is to the second phase
Syphilis is more to treat syphilis macula especially roserash to be good at.
[rules for the treatment of] internal cleaning By inducing sweat, wind and heat dispersing dehumidifying
（3）Tertiary syphilis：Late syphilis in the traditional Chinese medical science belongs to the category of tertiary syphilis, further, since tertiary syphilis can cause the heart
Blood vessel, nerve, bone, eye and other internal organ etc. lesion, thus it is clinical when answer diagnosis and treatment.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating syphilis；
It is a further object of the present invention to provide a kind of preparation method for the Chinese medicine composition for treating syphilis.
The purpose of the present invention is realized by following technical scheme：
The Chinese medicine composition for the treatment of syphilis of the present invention, is prepared by the raw material including following parts by weight：
Phoenix tree root 30-50 parts, beggar-ticks 30-50 parts, climbing groundsel 10-30 parts, baeckea frutescen leaf 10-30 parts, castor leaf 5-20 parts.
Preferably, it is to be prepared by the raw material including following parts by weight：
Phoenix tree root, for the root of Sterculiaceae plant Chinese parasol tree, wind-damp dispelling, and blood vessels, degrading the channel.Control pain in rheumatoid joints, discharging fresh blood stool,
Irregular menstruation, traumatic injury.
Beggar-ticks, it is the herb of feverfew beggar-ticks.Heat-clearing, removing toxic substances, dissipate the stasis of blood, detumescence.Preventing and curing malaria disease, diarrhoea, dysentery, liver
Inflammation, acute nephritis, stomachache, dysphagic, acute appendicitis, abscess of throat, traumatic injury, snake bite and insect sting.
Climbing groundsel, it is composite family Senecio plant climbing groundsel Senecio scandens Buch.-Ham., is entered with herb
Medicine.Hardship, it is pungent, it is cool.It is slightly poisonous.It is clearing heat and detoxicating, cool blood detumescence, clear liver and improve vision.For wind-fire red eye, sore furuncle poison, skin eczema
And the illness such as dysentery stomachache.
Baeckea frutescen leaf, Myrtaceae baeckea frutescen platymiscium baeckea frutescen Baeckea frutescens L. are used as medicine with leaf.It is pungent, bitter, puckery,
It is cool.Dispelling wind and eliminating dampness, diuresis of detoxifying, antalgesic-antipruritic.For venomous snake bite, burn and scald.
Castor leaf, the leaf of euphorbia plant castor-oil plant.Control tinea pedis, anti-tumour pain, asthma due to excessive phlegm of coughing, the fungal infection of the hand, boil.
Another aspect of the present invention there is provided the preparation method of the active component of Chinese medicine composition of the present invention, and this method is
It is prepared using the extraction of the ethanol of water extraction or 40-80% concentration expressed in percentage by volumes.Specific preparation method is as follows：
Scheme one：Take all 5 taste medicinal materials, extracting in water 2-3 times after mixing, 6-12 of each amount of water equivalent to medicinal material gross weight
Times, each extraction time is 1-3 hours, merges extract solution, filtration, relative density is 1.15- when filtrate is concentrated into 70-80 DEG C
1.20 clear cream, produces active component.
Scheme two：All 5 taste medicinal materials are taken, are extracted 2-3 times with 40-80% alcohol refluxs after mixing, each ethanol consumption is that medicinal material is total
4-10 times of amount, extraction time are 1-4 hours, merge extract solution, filtering, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, produces active component.
Scheme three：All 5 taste medicinal materials are taken, extracting in water 2-3 times after mixing, each amount of water is equivalent to medicinal material gross weight
6-12 times, each extraction time is 1-3 hours, merges extract solution, filtration, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, ethanol is added, it is 40-70% to make alcohol content, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80
DEG C when relative density be 1.10-1.25 medicinal extract, produce active component.
The Chinese medicine composition for the treatment of syphilis of the present invention, can be made with pharmaceutically acceptable carrier combination
Various conventional external preparations, as liniment, granule, lotion, tincture, finish, paste,（It is soft）Paste, press agent etc..
The pharmaceutically acceptable carrier of the present invention includes but is not limited to following：
Diluent：Distilled water, ethanol etc..
Cosolvent：The polyalcohols such as glycerine, sorbierite.
Preservative：Benzoic acid, sodium benzoate, propionic acid, parabens, ethyl-para-hydroxybenzoate etc..
Oleaginous base：Vaseline, liquid paraffin, lanolin, beeswax, animal oil, vegetable oil, glycerin monostearate,
Octadecyl alcolol etc. and its mixture,
Water-soluble base：Glycerine, sodium alginate, carbopol resin, starch gelatin, methylcellulose, sodium carboxymethylcellulose,
Polyethylene glycol, polyvinyl alcohol.
Transdermal enhancer：Cutin moisturizing diuretin, pyrrolones derivative, linoleic acid, laruyl alcohol, tween, dodecyl front three
Base ammonium bromide, dodecyl sodium sulfate, lauryl sodium sulfate, menthol, Laurocapram（Azone）Deng.
For example, it can be prepared as various common exterior-applied formulations by one of following method：
Method 1：Granule
Scheme one is taken to add granule and often use auxiliary material, routinely production method is prepared into one of to the gained active component of scheme three
Granule of the present invention.
Above-mentioned granule often includes one of diluent, wetting agent, adhesive, disintegrant or whole with auxiliary material.
Method 2：Liniment
Scheme one is taken to add liniment and often use auxiliary material one of to the gained active component of scheme three, routinely production method is prepared into
Invention liniment.
Above-mentioned liniment often includes one of diluent, preservative, cosolvent, transdermal enhancer or whole with auxiliary material.
Method 3：Paste
Scheme one is taken to add paste and often use auxiliary material one of to the gained active component of scheme three, routinely production method is prepared into
Invention paste.
Above-mentioned paste often includes one of oleaginous base, water-soluble base, preservative, transdermal enhancer or whole with auxiliary material.
Method 4：Lotion
Scheme one is taken after dilution, to add water to stir evenly, after standing filtering, produce one of to the gained active component of scheme three.
A kind of Chinese medicine composition for treating syphilis provided by the invention has advantages below：
1st, composition provided by the invention is safe and effective, there is a clearing heat and expelling damp, the work(of dispelling wind removing toxic substances, have to a phase, mesosyphilis compared with
Good curative effect.
2nd, composition provided by the invention has the effect of notable to syphilis, and total effective rate is up to 85.7%..
3rd, Traditional Chinese medicine composition formula of the present invention is rationally innovated, and production cost is low, technique is simple.
Embodiment
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are to be used to illustrate
The present invention rather than limitation of the present invention.The present invention is belonged to according to the simple modifications that the essence of the present invention is carried out to the present invention
Claimed scope.Unless otherwise indicated, the percentage of the amount of alcohol in the present invention is percentage by volume, and v/v represents solution
Volume ratio.
The lotion of embodiment 1
Weigh phoenix tree root 3kg, beggar-ticks 3kg, climbing groundsel 1kg, baeckea frutescen leaf 1kg, castor leaf 0.5kg.Extracting in water 3 times, three times
Amount of water is respectively 12 times of medicinal material gross weight, 8 times, 6 times, and extraction time is respectively 3 hours, 2 hours, 1 hour three times, is merged
Extract solution, filtration, relative density is 1.25 clear cream when filtrate is concentrated into 70 DEG C, adds the percent by volume of 2 times of clear cream weight
For 95% ethanol, stir evenly, stand 48 hours, filtration, filtrate recycling ethanol to 700mL, be added with water to 1000mL, stir evenly, stand
12h, refined filtration, packing, produce lotion of the present invention.
The granule of embodiment 2
Weigh phoenix tree root 5kg, beggar-ticks 5kg, climbing groundsel 3kg, baeckea frutescen leaf 3kg, castor leaf 2kg.3 are extracted with 40% alcohol reflux
Secondary, each ethanol consumption is respectively 10 times of medicinal material total amount, 8 times, 4 times, and extraction time is distinguished 3 hours, 2 hours, 1 hour, is closed
And extract solution, filtering, relative density is 1.25 medicinal extract when filtrate concentrates 60 DEG C, and adds auxiliary material dextrin, starch, mixes, with
Ethanol in proper amount is pelletized, and whole grain after 60 DEG C of dryings, particle is made, produces.
The granule of embodiment 3
Weigh phoenix tree root 3.5kg, beggar-ticks 3.5kg, climbing groundsel 1.5kg, baeckea frutescen leaf 1.5kg, castor leaf 1kg.Extracting in water 3
Secondary, amount of water is respectively equivalent to 12 times of medicinal material gross weight, 8 times, 6 times three times, each extraction time distinguish 3 hours, 2 hours, 1
Hour, merge extract solution, filtration, relative density is 1.20 clear cream when filtrate is concentrated into 70 DEG C, adds ethanol, makes the alcohol content be
40%, stand 24 hours, filtration, filtrate is concentrated into the medicinal extract that relative density when filtrate is concentrated into 70 DEG C is 1.10, add starch,
Dextrin, granulation, dry, whole grain produce.
The liniment of embodiment 4
Weigh phoenix tree root 4.5kg, beggar-ticks 4.5kg, climbing groundsel 2.5kg, baeckea frutescen leaf 2.5kg, castor leaf 1.5kg.Returned with ethanol
Stream extraction 2 times, each concentration of alcohol is respectively 80%, 60%, and each ethanol consumption is respectively 10 times of medicinal material total amount, 8 times, extraction
Time is respectively 4 hours, 3 hours, merges extract solution, filtering, relative density is 1.10 medicinal extract when filtrate is concentrated into 80 DEG C, is added
Purified water ad pond om is 2 times of medicinal material gross weight, adds 0.1% sodium benzoate, 0.05% methyl hydroxybenzoate, is mixed, point
Dress, produces liniment of the present invention.
The paste of embodiment 5
Weigh phoenix tree root 4kg, beggar-ticks 4kg, climbing groundsel 2kg, baeckea frutescen leaf 2kg, castor leaf 1.2kg.Extracting in water 2 times, twice
Amount of water is respectively 10 times of medicinal material gross weight, 8 times, and extraction time is respectively 2 hours, 1 hour twice, merges extract solution, filter
Cross, relative density is 1.10 medicinal extract when filtrate is concentrated into 80 DEG C, standby.
Stearic acid 15g is weighed, vaseline 100g, lanolin 80g, glyceryl stearate 35g, hexadecanol 80g, is heated to
85 DEG C, stir evenly, it is standby as oil phase;Separately take glycerine 130g, ethyl-para-hydroxybenzoate 2g, lauryl sodium sulfate 20g, the moon
Osmanthus Azone 25g, above-mentioned thick paste is added, water use regulation makes oil, the common 1000g of water two-phase, as aqueous phase, is heated to 90 DEG C, treats complete
After portion's dissolving, constant temperature stirs evenly to 85 DEG C；Oil phase is slowly added into aqueous phase, puts in refiner and stirs, is cooled down, is solidified, packing, i.e.,
Obtain paste of the present invention.
The paste of embodiment 6
Weigh phoenix tree root 3.8kg, beggar-ticks 4.2kg, climbing groundsel 2.3kg, baeckea frutescen leaf 1.8kg, castor leaf 1.8kg.Extracting in water 2
Secondary, each amount of water is respectively equivalent to 12 times of medicinal material gross weight, 10 times, and each extraction time is respectively 3 hours, 2 hours, closes
And extract solution, filtration, filtrate are concentrated into the clear cream that relative density at 80 DEG C is 1.05, add ethanol, it is 70% to make alcohol content, quiet
Put 12 hours, filter, relative density is 1.25 medicinal extract when filtrate is concentrated into 70 DEG C, standby.
Stearic acid 18g is weighed, vaseline 100g, lanolin 80g, glyceryl stearate 30g, hexadecanol 82g, is heated to
85 DEG C, stir evenly, it is standby as oil phase;Separately take glycerine 110g, ethyl-para-hydroxybenzoate 4g, lauryl sodium sulfate 30g, the moon
Osmanthus Azone 30g, above-mentioned thick paste is added, water use regulation makes oil, the common 1000g of water two-phase, as aqueous phase, is heated to 90 DEG C, treats complete
After portion's dissolving, constant temperature stirs evenly to 85 DEG C；Oil phase is slowly added into aqueous phase, puts in refiner and stirs, is cooled down, is solidified, packing, i.e.,
Obtain paste of the present invention.
The pulvis of embodiment 7
Weigh phoenix tree root 4.2kg, beggar-ticks 3.8kg, climbing groundsel 1.8kg, baeckea frutescen leaf 2.3kg, castor leaf 0.8kg.Crush, mistake
Sieve, is produced.
Embodiment 8
Lotion prepared by the embodiment of the present invention 1, syphilitic patient's external application is given, 2 times a day, clinical data is as follows：
| Disorder class | Illness number of cases | The course of disease | Treatment time | Efficiently individual quantity | Total effective rate |
| Syphilis | 35 | - 1 year April | The 2-3 months | 30 | 85.7% |
Embodiment 9
Cao XX, women, 25 years old, perineum fash was diagnosed as the syphilis second phase more than March, through physical examination and laboratory examination.,
After the embodiment of the present invention 6 is treated three weeks, fash flattens, and leaves filbert pigmentation.
Claims (7)
1. a kind of Chinese medicine composition for treating syphilis, it is characterised in that it is to include being prepared by the raw material of following parts by weight
's：Phoenix tree root 30-50 parts, beggar-ticks 30-50 parts, climbing groundsel 10-30 parts, baeckea frutescen leaf 10-30 parts, castor leaf 5-20 parts.
2. the Chinese medicine composition for the treatment of syphilis as claimed in claim 1, it is characterised in that it is by including following parts by weight
What raw material was prepared：Phoenix tree root 35-45 parts, beggar-ticks 35-45 parts, climbing groundsel 15-25 parts, baeckea frutescen leaf 15-25 parts, castor leaf
10-15 parts.
3. the Chinese medicine composition for the treatment of syphilis as claimed in claim 1 or 2, it is characterised in that its active component is to use water
Carry or the extraction of the ethanol of 40-80% concentration expressed in percentage by volumes is prepared.
4. the Chinese medicine composition for the treatment of syphilis as claimed in claim 3, it is characterised in that its active component is by following
What method was prepared：All 5 taste medicinal materials are taken, extracting in water 2-3 times after mixing, each amount of water is equivalent to medicinal material gross weight
6-12 times, each extraction time is 1-3 hours, merges extract solution, filtration, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, produces active component.
5. the Chinese medicine composition for the treatment of syphilis as claimed in claim 3, it is characterised in that its active component is by following
What method was prepared：All 5 taste medicinal materials are taken, are extracted 2-3 times with 40-80% alcohol refluxs after mixing, each ethanol consumption is medicine
4-10 times of material total amount, extraction time are 1-4 hours, merge extract solution, filtering, relative density when filtrate is concentrated into 70-80 DEG C
For 1.15-1.20 clear cream, active component is produced.
6. the Chinese medicine composition for the treatment of syphilis as claimed in claim 3, it is characterised in that its active component is by following
What method was prepared：All 5 taste medicinal materials are taken, extracting in water 2-3 times after mixing, each amount of water is equivalent to medicinal material gross weight
6-12 times, each extraction time is 1-3 hours, merges extract solution, filtration, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, ethanol is added, it is 40-70% to make alcohol content, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80
DEG C when relative density be 1.10-1.25 medicinal extract, produce active component.
A kind of 7. Chinese medicine composition for treating syphilis, as Chinese medicine composition and the medicine of the treatment syphilis described in claim 1 or 2
Acceptable carrier combination is prepared on.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711133551.5A CN107875198A (en) | 2017-11-16 | 2017-11-16 | A kind of Chinese medicine composition for treating syphilis and preparation method thereof |
Applications Claiming Priority (1)
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| CN201711133551.5A CN107875198A (en) | 2017-11-16 | 2017-11-16 | A kind of Chinese medicine composition for treating syphilis and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1086900A (en) * | 1913-02-28 | 1914-02-10 | Kalil David | Remedy for syphilis. |
| CN1220878A (en) * | 1997-12-22 | 1999-06-30 | 邓恺 | Vaginal protective agent |
| WO2001078704A2 (en) * | 2000-04-13 | 2001-10-25 | Evans William T | Gaba substrate and the use thereof for treating cognitive and emotional disorders |
-
2017
- 2017-11-16 CN CN201711133551.5A patent/CN107875198A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1086900A (en) * | 1913-02-28 | 1914-02-10 | Kalil David | Remedy for syphilis. |
| CN1220878A (en) * | 1997-12-22 | 1999-06-30 | 邓恺 | Vaginal protective agent |
| WO2001078704A2 (en) * | 2000-04-13 | 2001-10-25 | Evans William T | Gaba substrate and the use thereof for treating cognitive and emotional disorders |
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