CN107854546A - Dog, cat cough suppressing medicine and preparation method thereof - Google Patents

Dog, cat cough suppressing medicine and preparation method thereof Download PDF

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Publication number
CN107854546A
CN107854546A CN201711095961.5A CN201711095961A CN107854546A CN 107854546 A CN107854546 A CN 107854546A CN 201711095961 A CN201711095961 A CN 201711095961A CN 107854546 A CN107854546 A CN 107854546A
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parts
medicine
cat
cough
dog
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王秀君
李正
王永兴
阎峰
侯显涛
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Henan University of Animal Husbandry and Economy
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Henan University of Animal Husbandry and Economy
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
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  • Medical Informatics (AREA)
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  • Biotechnology (AREA)
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  • Engineering & Computer Science (AREA)
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Abstract

The invention discloses a kind of dog, cat cough suppressing medicine and preparation method thereof, it is intended to solves conventional medication dog, cat cough and asthma is ineffective, has the technical problem of side effect.The Chinese medicine preparation is made up of gingko, semen armeniacae amarae, earthworm, the root bark of white mulberry, dried orange peel, radix scutellariae, Poria cocos, Cynanchum glaucescens, kuh-seng, radix glycyrrhizae, auxiliary material, is boiled by heating to obtain.According to substantial amounts of clinical observation, verification type, clinical manifestation and treatment prognosis etc. carry out comprehensive analysis, cough suppressing medicine reasonable recipe of the present invention, each component synergy, its cough-relieving, relieving asthma, resolving sputum effect it is notable；The preparation method of the medicine is simple, easy to use, is adapted to the needs of scale industrial production.

Description

Dog, cat cough suppressing medicine and preparation method thereof
Technical field
The present invention relates to animal technical field of Chinese medicine, and in particular to a kind of dog, cat cough suppressing medicine and preparation method thereof.
Background technology
With the development of social economy and the acceleration of urbanization process, people's cultural life and living standard are increasingly One of improve, social senilization paces are accelerated, and raising pet has become many people's leisure, loosened with emotion sustenance mode, into For a kind of pastime of people's life.It except bring people it is many it is happy in addition to, mental health to the mankind, ease off the pressure It is very helpful, " companion animals " is often referred to as by people's cordiality.However, pet also often suffers from various common diseases Disease influences its quality of life.Therefore, while raising pets quantity is more and more, Medical pet also increasingly causes social pass Note.
Pet during feeding management, change due to environment, caused by the generation of disease using cough and asthma as primary symptom Respiratory infectious disease or inflammation room clinically one of relatively common symptom.Cough is that a kind of defence of animal body acts, energy Foreign body in respiratory tree and pathological discharge thing are excreted, play a part of to exclude foreign matter cleaning respiratory tract, meanwhile, cough also can Body is damaged.Winter-Spring and climate variability season often occur, and are not limited by age, kind.
Although China's Medical pet was quickly grown at nearly 10 years, treatment method is mainly with the Western medicine such as antibiotic or anti- Raw element is used cooperatively with Chinese medicine, and its major drawbacks is easily to fall ill repeatedly, and cure rate is not high.Curative effect both cannot be guaranteed, and deposit again In many safety issues such as medicament residue, and there is the shortcomings of cost is high, side effect is big.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of reasonable recipe, compatibility degree of having, raw material sources are extensive, to prescription Just, have no toxic side effect, the dog of pure Chinese medicinal preparation, cat cough suppressing medicine and preparation method thereof.
In order to solve the above technical problems, the present invention adopts the following technical scheme that：
A kind of dog, cat cough suppressing medicine, are made up of the bulk drug of following weight：8~12 parts of gingko, 8~12 parts of semen armeniacae amarae, earthworm 4 ~6 parts, 8~12 parts of the root bark of white mulberry, 4~6 parts of dried orange peel, 8~12 parts of radix scutellariae, 4~6 parts of Poria cocos, 8~12 parts of Cynanchum glaucescens, 4~6 parts of kuh-seng, 4~6 parts of radix glycyrrhizae, 230~260 parts of auxiliary material.
Preferably, the dog, cat cough suppressing medicine are made up of the bulk drug of following parts by weight：10 parts of gingko, 10 parts of semen armeniacae amarae, 5 parts of earthworm, 10 parts of the root bark of white mulberry, 5 parts of dried orange peel, 10 parts of radix scutellariae, 5 parts of Poria cocos, 10 parts of Cynanchum glaucescens, 5 parts of kuh-seng, 5 parts of radix glycyrrhizae, auxiliary material 250 Part.
It is further preferred that the auxiliary material is at least one of dextrin, starch, glucose.
It is further preferred that the medicine is pill or tablet.
Above-mentioned dog, the preparation method of cat cough suppressing medicine, including following preparation technology：
（1）Decoct for the first time：Each bulk drug in addition to auxiliary material is weighed according to proportioning, extractor is put into, to extractor plus water, intense fire Boil, be then cooked by slow fire 25~35min, by medical filtration to fluid reservoir, the dregs of a decoction are recycled to extractor；
（2）Second of decoction：Into the dregs of a decoction plus water, boil by intense fire, be then cooked by slow fire 30min, then by medical filtration to liquid storage Tank, the dregs of a decoction are recycled to extractor；
（3）Concentration：The decoction for decocting extraction twice is merged, paste is concentrated into, obtains Chinese medicine paste；
（4）Dextrin, starch, glucose are weighed by proportioning, is added in Chinese medicine paste, is stirred and evenly mixed, ointment is made；
（5）Softwood is put into the funnel of tablet press machine, starts tabletting.
Compared with prior art, advantageous effects of the invention are：
1. the present invention uses pure Chinese medicinal preparation, grope meticulously by long-term, substantial amounts of practical studies, with reference to modern medicine medicine Achievement in research is managed, develops and obtains, is mainly used in treating dog, cats to cough as the breathing problem of cardinal symptom, is administered It is convenient, have no toxic side effect, therapeutic effect is significantly better than commercially available conventional dog cat pectoral.
It is 2. relieving cough and reducing sputum to relieving asthma with gingko, semen armeniacae amarae, Cynanchum glaucescens three altogether for monarch drug in a prescription in side of the present invention；Earthworm, the root bark of white mulberry, Radix scutellariae, clearing lung-heat heat and cough-relieving, monarch drug in a prescription can be aided in, be altogether ministerial drug；Dried orange peel, Poria cocos, kuh-seng, invigorating the spleen, clearing damp, heat-clearing, it is altogether assistant Medicine；Radix glycyrrhizae mediation property of medicine, to make medicine.
3. raw material sources of the present invention are extensive, by traditional Chinese medicine reasonable formula, medicinal essence is special, compatibility degree of having, all medicines share, Each component acts synergistically；Its formulation of Chinese medicine preparation of the present invention is tablet or pill, easy to use, is easy to preserve and carries.
4. the preparation method of the medicament is simple in the present invention, no complicated equipment and cumbersome technique, scale is facilitated to grasp Make, cost is cheap, remarkable in economical benefits.
The pharmacological effect of primary raw material medicine is summarized as follows in side：
Gingko, also known as ginkgo nut：Sweet and slightly bitter taste, the gas that can astringe the lung, asthma of coughing surely, reduce amount of expectoration, eliminating phlegm relieving asthma.
Semen armeniacae amarae：Bitter, tepor, it is slightly poisonous；Sending down abnormally ascending is relieving cough and asthma, relaxes bowel, and relieving cough and asthma effect is good.
Earthworm：Cold in nature, taste is salty, has heat-clearing, antispastic, Zhichuan, diuresis to function；Return liver, stomach, lung, bladder warp, clearing lung-heat are put down Asthma, for lung heat asthma；Accumulation of pathogenic heat in the lung is controlled, impairment of purifying and descending function of the lung is gasped for breath, whistling sound in the throat person, and alone grind is taken orally i.e. Effect, can also be equal with Chinese ephedra, gypsum, almond and use.
The root bark of white mulberry：It is sweet, tremble with fear, enter lung channel；Removing heat from lung and relieving asthma, line water detumescence；The root bark of white mulberry focuses on purging the lung of pathogenic fire heat and flat cough and asthma, is used for Lung has hot, hot phlegm to stop up the cough of lung, asthma, phlegm Huang person：For lying prostrate the strongly fragrant lung of fire, symptoms include coughing with a lot of sputum, color Huang are sticky；Breathed heavily for lung heat It is inverse, symptoms include cough and asthma gas gushes, breath slightly promotees；For liver-fire attacking lung, liverzang-fire attacking lung, symptoms include circulation of vital energy in the wrong direction cough and asthma.
Dried orange peel：It is bitter, pungent, it is warm-natured.Return lung, the spleen channel.Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For coughing with a lot of sputum.
Radix scutellariae：Nature and flavor：Hardship, tremble with fear.Channel tropism：Enter the heart, lung, courage, large intestine channel.Control high fever polydipsia, cough with lung heat.
Poria cocos：It is sweet, light, it is mild-natured.The thoughts of returning home, lung, spleen, kidney channel.Clearing damp and promoting diuresis, invigorating the spleen, calming heart.For oedema oliguria, phlegm Drink feel dizzy and heart palpitations, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Cynanchum glaucescens：It is pungent, bitter, tepor.Lowering the adverse-rising QI to resolve phlegm, cough-relieving.Purging the lung of pathogenic fire sending down abnormally ascending, lower phlegm are only coughed, hemoptysis.Controlling lung, asthma is full in fact, cough, More phlegm, gastral cavity pain.
Kuh-seng：Bitter, it is cold in nature.The thoughts of returning home, liver, stomach, large intestine, bladder warp.Heat-clearing and damp-drying drug, desinsection, diuresis.
Embodiment
Technical scheme is described in detail with reference to specific embodiment, but following examples are not in any way Limit the scope of the present invention.Involved reagent is commercially available conventional reagent unless otherwise instructed in following examples.
Embodiment 1
A kind of dog, cat cough suppressing medicine, are made up of the bulk drug of following weight：The g of gingko 10, the g of semen armeniacae amarae 10, earthworm 5 g, Sang Bai The g of skin 10, the g of dried orange peel 5, the g of radix scutellariae 10, the g of Poria cocos 5, the g of Cynanchum glaucescens 10, the g of kuh-seng 5, radix glycyrrhizae 5 g, dextrin 15g, starch 30g, Disintegrant 5g, the g of glucose 200.
The medicine is prepared by the following method：
（1）Decoct for the first time：Claim each bulk drug in addition to dextrin, starch, disintegrant, glucose according to said ratio, put into Extractor, exceed powder 2cm to extractor plus water, boil by intense fire, after then slow fire keeps 25~35 min, by medical filtration extremely Fluid reservoir, the dregs of a decoction are recycled to extractor；
（2）Second of decoction：Add water to equal with powder, boil by intense fire into the dregs of a decoction, then slow fire keeps 30min, then by medicine Liquid filters to fluid reservoir, the dregs of a decoction and is recycled to extractor；
（3）Concentration：The decoction for decocting extraction twice is merged, paste is concentrated into, obtains Chinese medicine paste；
（4）Dextrin 15g, starch 30g, disintegrant 5g, glucose 200g are weighed, gained Chinese medicine paste is walked in addition, is stirred Mixing is mixed, softwood is made；
（5）By the softwood tabletting machine of upper step, you can.
Embodiment 2
A kind of dog, cat cough suppressing medicine, are made up of the bulk drug of following weight：Gingko 12g, semen armeniacae amarae 8g, earthworm 6g, the root bark of white mulberry 12g, dried orange peel 4g, radix scutellariae 8g, Poria cocos 6g, Cynanchum glaucescens 8g, kuh-seng 5g, radix glycyrrhizae 4g, dextrin 12g, starch 26g, disintegrant 5g, Portugal Grape sugar 187g.
The preparation method of the medicine is same as Example 1.
Embodiment 3
A kind of dog, cat cough suppressing medicine, are made up of the bulk drug of following weight：Gingko 9g, semen armeniacae amarae 12g, earthworm 5g, the root bark of white mulberry 8g, dried orange peel 6g, radix scutellariae 12g, Poria cocos 4g, Cynanchum glaucescens 12g, kuh-seng 6g, radix glycyrrhizae 6g, dextrin 17g, starch 30g, disintegrant 7g, Glucose 206g.
The preparation method of the medicine is same as Example 1.
The treatment of dog, cat cough suppressing medicine prepared by the embodiment of the present invention 1 for shepherd dog cough, to its treatment results Verified, detailed process is as follows：
Choose 600 illness（Cough）Shepherd dog, be by age divided into eight groups, experimental group 1 to 4, control group 1 to 4, every group 25 Only, and three repetitions are set, the ill shepherd dog age that control group corresponds to group is identical with experimental group.Wherein, experimental group illness is herded The Chinese medicine preparation treatment that sheep dog is prepared using the embodiment of the present invention 1, control group are controlled using conventional commercial cat, dog with cough stopping tablet Treat, administration time, dosage are all consistent, referring specifically to table 1, table 2：
It can be seen from table 1, table 2 compared with the medicine that conventional commercial is used for dog cat cough-relieving, for identical illness, phase is taken With the medicine of dosage, cough suppressing medicine prepared by the present invention has obvious advantage in therapeutic effect.
Model case
A Cibotium barometz (L.) J. Sm cough case 1. Zhengzhou Wang Wang pet clinics see and treat patients in November, 2016, female, 2 years old, body weight 12 was public Jin, body temperature is slightly higher, coughs, and has a running nose, the in disorder tarnish of hair, is diagnosed as pure cough due to wind-cold evil.Prepared by the oral present invention Cough suppressing medicine, twice a day, take 2 days, symptom substantially mitigates, and continues to take one day again.Further consultation after taking three days, substantially Recovery from illness, simply coughs once in a while.Continue to take the cough suppressing medicine, once a day, one time 2, be used in conjunction two days, further consultation, fully recover.
2. pets hospital in December, 2016 is wished in Anhui, the young cat of or so two weeks is adopted, sneezing, nasal cavity dryness, nasal obstruction, Intraocular has secretion, breathes obvious not smooth.Once repeatedly gone to a doctor before taking cough suppressing medicine of the present invention, Relapse rate is ineffective.Clothes With cough suppressing medicine of the present invention, one at a time, twice a day, it is used in conjunction 3 days, has fully recovered during further consultation.
3. Agricultural University Of Anhui's pets hospital, see and treat patients March 20 in 2017 one and win U.S. dog, 1 years old, 1 kilogram of body weight, cough, Have a running nose, shake.With this film, one at a time, twice a day, once every three days, symptom disappears.

Claims (5)

1. a kind of dog, cat cough suppressing medicine, it is characterised in that be made up of the bulk drug of following parts by weight：8~12 parts of gingko, bitter apricot 8~12 parts of benevolence, 4~6 parts of earthworm, 8~12 parts of the root bark of white mulberry, 4~6 parts of dried orange peel, 8~12 parts of radix scutellariae, 4~6 parts of Poria cocos, Cynanchum glaucescens 8~ 12 parts, 4~6 parts of kuh-seng, 4~6 parts of radix glycyrrhizae, 230~260 parts of auxiliary material.
2. dog according to claim 1, cat cough suppressing medicine, it is characterised in that be made up of the bulk drug of following parts by weight：In vain 10 parts of fruit, 10 parts of semen armeniacae amarae, 5 parts of earthworm, 10 parts of the root bark of white mulberry, 5 parts of dried orange peel, 10 parts of radix scutellariae, 5 parts of Poria cocos, 10 parts of Cynanchum glaucescens, kuh-seng 5 Part, 5 parts of radix glycyrrhizae, 250 parts of auxiliary material.
3. dog according to claim 1 or 2, cat cough suppressing medicine, it is characterised in that the auxiliary material is dextrin, starch, grape At least one of sugar, disintegrant.
4. dog according to claims 1 to 3, cat cough suppressing medicine, it is characterised in that the medicine is pill or tablet.
5. dog described in Claims 1 to 4, the preparation method of cat cough suppressing medicine, it is characterised in that comprise the following steps：
（1）Decoct for the first time：Each bulk drug in addition to auxiliary material is weighed according to proportioning, adds water after mixing thereto, boils by intense fire, so After be cooked by slow fire 25~35min, filter to obtain decoction, dregs of a decoction recovery；
（2）Second of decoction：Add water into the dregs of a decoction, boil by intense fire, be then cooked by slow fire 30min, secondary filter obtains decoction；
（3）Concentration：The decoction for decocting extraction twice is merged, paste is concentrated into, obtains Chinese medicine paste；
（4）Dextrin, starch, glucose, disintegrant are weighed by proportioning, Chinese medicine paste is added thereto, stirred and evenly mixed, is made soft Material；
（5）Softwood is put into the funnel of tablet press machine, starts tabletting.
CN201711095961.5A 2017-11-06 2017-11-06 Dog, cat cough suppressing medicine and preparation method thereof Pending CN107854546A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1660181A (en) * 2004-12-29 2005-08-31 哈药集团世一堂制药厂 Medication for treating acute upper respiratory infection and acute bronchitis and preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1660181A (en) * 2004-12-29 2005-08-31 哈药集团世一堂制药厂 Medication for treating acute upper respiratory infection and acute bronchitis and preparation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王玉等: "喘嗽宁治疗哮喘308例的疗效观察", 《中华中医药杂志》 *

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