CN107823314A - A kind of new medicine composition for treating headache and preparation method - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of new medicine composition for treating headache according to the understanding mechanism that Chinese traditional treatment is had a headache, each component and its mass parts ratio of the Chinese medicine composition are as follows：30~350g of yncaria stem with hooks, 30~120g of Ligusticum wallichii, 80~160g of the root of kudzu vine, 30~120g of Chinese ephedra, 15~100g of asarum, 30~150g of RADIX ACONITI LATERALIS PREPARATA, 30~120g of radix bupleuri, 60~160g of the root of herbaceous peony, 100~260g of notopterygium root, 30~150g of levisticum, 30~100g of radix scutellariae, windproof 50~120g, 100~360g of glutinous rehmannia, 80~160g of Radix Angelicae Sinensis, 15~60g of evodia rutaecarpa, 100~160g of reticulate millettia, 80~160g of peach kernel, 30~120g of safflower, 30~120g of the root of Dahurain angelica, 30~100g of Jehol Ligusticum Rhizome；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of new medicine composition for treating headache and preparation method

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of new medicine composition for treating headache, particularly supply The new medicine composition and the field of preparation method that headache uses.

Background technology

Shown according to documents and materials：Headache（headache）It is clinical common symptom, generally will be limited to the head first half, Headache is referred to as with the pain of upper bit including geisoma, helix upper limb and pillow outer knuckle line.Headache is because various, neuralgia, cranium Interior infection, intracranial space-occupying lesion, cranial vascular disease, cranium the outside maxillofacial disease and general disease such as acute infection, poisoning etc. are equal It can cause to have a headache.Age of onset is common in young, middle age and old age.

Clinical manifestation：

Headache degree has and gently has weight, and pain time has with short.Pain form is varied, common distending pain, vexed pain, tear sample Bitterly, shock by electricity sample pain, prickling-like pain, partly with vascular pulsation sense and head lock ring sense, and the disease such as Nausea and vomiting, dizziness Shape.Secondary headache can also be often accompanied by generating heat with other systems disease symptomses or sign, such as infectious diseases, vascular lesion Often with neurologic impairment symptoms such as hemiplegia, aphasia etc..Headache produces different harm according to degree, and patient can be lost by being in a bad way Lose live and work ability.

So, just how to find a kind of new medicine composition that can effectively treat headache, be those skilled in the art urgently The problem of to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment headache, people gradually appreciate Chinese traditional treatment head The advantages of pain, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for the headache of existing western medical treatment Present situation, the purpose of the present invention is to be to provide a kind of new medicine composition for treating headache, extensive early to solve headache The problem of rehabilitation health.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively be controlled Treat the above-mentioned disease of headache one.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：There is provided and a kind of treat the new of headache Chinese medicine composition and preparation method, it is characterised in that each component and mass parts of the Chinese medicine composition are than as follows：

30~350g of yncaria stem with hooks, 30~120g of Ligusticum wallichii, 80~160g of the root of kudzu vine, 30~120g of Chinese ephedra, 15~100g of asarum, RADIX ACONITI LATERALIS PREPARATA 30 It is~150g, 30~120g of radix bupleuri, 60~160g of the root of herbaceous peony, 100~260g of notopterygium root, 30~150g of levisticum, 30~100g of radix scutellariae, windproof 50~120g, 100~360g of glutinous rehmannia, 80~160g of Radix Angelicae Sinensis, 15~60g of evodia rutaecarpa, 100~160g of reticulate millettia, peach kernel 80~ 160g, 30~120g of safflower, 30~120g of the root of Dahurain angelica, 30~100g of Jehol Ligusticum Rhizome, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and starch are fitted Amount.

A kind of new medicine composition for treating headache and preparation method, it is characterised in that the Chinese medicine composition it is each Individual component and mass parts are than as follows：

38~310g of yncaria stem with hooks, 38~105g of Ligusticum wallichii, 90~140g of the root of kudzu vine, 38~105g of Chinese ephedra, 20~90g of asarum, RADIX ACONITI LATERALIS PREPARATA 38 It is~130g, 38~105g of radix bupleuri, 70~140g of the root of herbaceous peony, 115~230g of notopterygium root, 38~130g of levisticum, 38~90g of radix scutellariae, windproof 58~105g, 115~320g of glutinous rehmannia, 90~120g of Radix Angelicae Sinensis, 20~45g of evodia rutaecarpa, 120~130g of reticulate millettia, peach kernel 100~ 120g, 45~105g of safflower, 38~105g of the root of Dahurain angelica, 45~80g of Jehol Ligusticum Rhizome, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and starch are fitted Amount.

A kind of new medicine composition for treating headache and preparation method, it is characterised in that the Chinese medicine composition it is each Individual component and mass parts are than as follows：

Yncaria stem with hooks 280g, Ligusticum wallichii 95g, root of kudzu vine 120g, Chinese ephedra 95g, asarum 80g, RADIX ACONITI LATERALIS PREPARATA 115g, radix bupleuri 95g, root of herbaceous peony 120g, Qiang Work 200g, levisticum 115g, radix scutellariae 80g, windproof 95g, glutinous rehmannia 260g, Radix Angelicae Sinensis 105g, evodia rutaecarpa 40g, reticulate millettia 115g, peach kernel 105g, safflower 95g, root of Dahurain angelica 95g, Jehol Ligusticum Rhizome 70g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

A kind of new medicine composition for treating headache and preparation method, it is characterised in that methods described includes following step Suddenly it is prepared：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is ground into according to mass parts than altogether（30~50 mesh）Graininess bag Decoct；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 50min, then soaked medicine is put into marmite again, The cold boiling water for adding 8~9 times of raw material Chinese medicine weight carries out first time high heat decoction, when 18min is arrived in decoction, turns slow fire and boils 120min, leaching decoction；2. the cold boiling water for adding 7~8 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time Boil, when 15min is arrived in decoction, turn slow fire and boil 110min, leaching decoction；3. decoction mixing twice is condensed into relative density is 1.08 clear cream, then dry, grind and sterilize after it is standby；

C, the method for 1. preparing Chinese medicine capsules according to tradition, after smalls sieving ground in " B ", appropriate micro mist is added Silica gel, microcrystalline cellulose and starch, are mixed evenly, and are then prepared into capsule（Total length is after its capsule is sealed 23.3mm, medicinal powder capacity 0.4~0.5g/ grains）, 2. then polish, sterilize, sealed packaging.

A kind of new medicine composition for treating headache and preparation method, it is characterised in that the instructions of taking is：Will system The capsule medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 3g（6）/ time, warm water delivery service, 3 days For a course for the treatment of, after 1~2 course for the treatment of of taking medicine, symptom disappears, and disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Yncaria stem with hooks, nature and flavor：Sweetness and bitterness, it is slightly cold, there is the effect of The flat liver of heat-clearing, relieving convulsion and spasm, for treating child convulsion, the morbid night crying of babies, heat Contain the diseases such as dynamic wind, eclampsia, dizziness due to hyperactivity of liver-YANG, irascibility distending pain in the head；

Ligusticum wallichii, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation, promote breath and open depression, wind-expelling pain-stopping, for treating menstruation not The stagnant raw meat pain of tune, closed dysmenorrhea, the postpartum stasis of blood, abdominal mass lump, pain in chest and hypochondrium, dizziness of having a headache, wind-cold-dampness arthralgia, traumatic injury, ulcer sore Ulcer；

The root of kudzu vine, nature and flavor：It is sweet, pungent, flat, have expelling pathogenic factors from muscles and skin bring down a fever, deliver examine, promote the production of body fluid to quench thirst, Shengyang Zhixie the effect of, for treating Fever caused by exogenous pathogens, rigidity of nape and headache, measles go out that not smooth, warm disease is thirsty, diabete, diarrhea, dysentery, hypertension, coronary heart disease etc. from the beginning of, rash Disease；

Chinese ephedra, nature and flavor：Arduous, temperature, have sweating, relieving asthma, sharp water the effect of, for treat typhoid fever table is real, fever with chilliness is lossless, Headache nasal obstruction, arthralgia, cough and asthma, geomantic omen edema, difficult urination, the stupid numbness of ailment said due to cold or exposure, munbness, rubella itch；

Asarum, nature and flavor：It is pungent, warm, there is wind-dispelling, cold dispelling, water-filling, the effect of having one's ideas straightened out, for treat air-cooled headache, nasosinusitis, dentalgia, The diseases such as phlegm and retained fluid cough is inverse, arthralgia pain due to rheumatism；

RADIX ACONITI LATERALIS PREPARATA, nature and flavor：Pungent, sweet, big heat, it is poisonous, there is recuperating depleted yang, mends fire supporing yang, the effect of by wind-cold damp pathogen, for controlling Treat yang depletion collapse, cold weak pulse of limb, impotence, Gong Leng, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors, numbness and ache of cold dampness；

Radix bupleuri, nature and flavor：Bitter, pungent, cold nature, there is inducing diaphoresis to bring down a fever, soothing liver-qi stagnation, rise the effect of lifting yang-energy, it is outer for treating Feel heating, fevers and chills alternate, malaria, liver-depressed hypochondrium pain mammary swelling, have a headache a dizzy, irregular menstruation, the prolapse of the anus of collapse from qi deficiency, the prolapse of uterus, The diseases such as gastroptosis；

The root of herbaceous peony, nature and flavor：Bitter, acid, it is slightly cold, there is the effect of smooth liver and relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating, it is dizzy for treating headache The disease such as dizzy, hypochondriac pain, stomachache, four limbs contraction pain, blood deficiency chlorosis, irregular menstruation, spontaneous perspiration, night sweat；

Notopterygium root, nature and flavor：Arduous, temperature, has the effect of dissipating exterior cold, wind-damp dispelling, sharp joint, for treating cold, headache nothing Sweat, wind-cold-dampness arthralgia, item strengthening tendons urgency, joint ache, geomantic omen edema, skin sore；

Levisticum, nature and flavor：Pungent, bitter, tepor, there is the effect of dispelling wind and eliminating dampness, numbness relieving and pain relieving, for treating wind-cold-dampness arthralgia, waist and knee pain Bitterly, few the moon volt wind headache；

Radix scutellariae, nature and flavor：It is bitter, cold in nature, have clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, it is antiabortive the effect of, for treating lung heat cough Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle Swollen furunculosis illness；

It is windproof, nature and flavor：Acrid flavour, sweet, slightly warm in nature, have expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, spasmolysis, it is antipruritic the effect of, it is outer for treating Feel chill, headache bodily pain, arthralgia pain due to rheumatism, skeletal pain, stomachache diarrhea, discharging fresh blood stool, lockjaw, rubella itch, sore from the beginning of；

Glutinous rehmannia, nature and flavor：It is sweet, cold, there is clearing heat and cooling blood, yin-nourishing, the effect of promoting the production of body fluid, for treating the deep red polydipsia of pyreticosis tongue, in the deficiency of Yin Heat, hectic fever due to yin labor heat, Heat Diabetes, haematemesis, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis；

Radix Angelicae Sinensis, nature and flavor：It is sweet, pungent, slight bitter, warm-natured, there is the effect of benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, for treating Irregular menstruation, Amenorrhea stomachache, Disorder lumps in the abdomen knot are poly-, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, intestines are dry and shit is difficult, weight after dysentery characterized by blood in the stool, ulcer sore Surreptitiously, the illness such as injury from falling down；

Evodia rutaecarpa, nature and flavor：It is pungent, bitter, hot, mild toxicity, there is the effect of eliminating cold to stop pain, soothing the liver lower gas, middle benefit gas eliminating dampness, for treating gastral cavity Abdomen crymodynia, jueyin headache, colic, tinea pedis swelling and pain, vomiting acid regurgitation, cold-dampness diarrhea；

Reticulate millettia, nature and flavor：It is bitter, micro-sweet, warm-natured, there is the effect of activating blood and relaxing tendons, nourishing blood for regulating menstruation, for treat it is numb in every limb, Quadriplegia, arthralgia pain due to rheumatism, women have through diseases such as uncomfortable, dysmenorrhoea, amenorrhoeas；

Peach kernel, nature and flavor：It is bitter sweet, flat, there is the effect of blood-breaking row stasis of blood, moisturize laxation, for treating Amenorrhea, Disorder lumps in the abdomen, pyreticosis stores blood, The dry constipation of wandering arthritis, malaria, traumatic injury, blood stasis and swelling pain, blood；

Safflower, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation can be through, stasis-dispelling and pain-killing, for treating Amenorrhea, dysmenorrhoea, the postpartum stasis of blood The diseases such as resistance stomachache, born of the same parents' numbness pained a lump in the abdomen causing distension and pain, traumatic injury, arthralgia, middle windage yaw are completed, macula；

The root of Dahurain angelica, nature and flavor：It is acrid flavour, warm-natured, there is dispelling wind and eliminating dampness, logical the effect of stealing analgesic, detumescence and apocenosis, for treating head of catching a cold Bitterly, pain in the supra-orbital bone, toothache, nasal obstruction, nasosinusitis, wet victory chronic diarrhea, women leukorrhea, ulcer sores, venomous snake bite；

Jehol Ligusticum Rhizome, nature and flavor：It is pungent, warm, have wind-dispelling, cold dispelling, dehumidifying, analgesic the effect of, for treat anemofrigid cold, mountain peak top pain, Rheumatism podomere numbness pain.

Medicine of the present invention is the principle based on Chinese traditional treatment headache, is recognized from the pathomechanism according to headache and pharmacological action For：With regard to headache, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned headache, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of new medicine composition for treating headache, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows：

Yncaria stem with hooks 280g, Ligusticum wallichii 95g, root of kudzu vine 120g, Chinese ephedra 95g, asarum 80g, RADIX ACONITI LATERALIS PREPARATA 115g, radix bupleuri 95g, root of herbaceous peony 120g, Qiang Work 200g, levisticum 115g, radix scutellariae 80g, windproof 95g, glutinous rehmannia 260g, Radix Angelicae Sinensis 105g, evodia rutaecarpa 40g, reticulate millettia 115g, peach kernel 105g, safflower 95g, root of Dahurain angelica 95g, Jehol Ligusticum Rhizome 70g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Embodiment 2：

A kind of new medicine composition for treating headache, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows：

Yncaria stem with hooks 310g, Ligusticum wallichii 105g, root of kudzu vine 140g, Chinese ephedra 105g, asarum 90g, RADIX ACONITI LATERALIS PREPARATA 130g, radix bupleuri 105g, root of herbaceous peony 140g, Notopterygium root 230g, levisticum 130g, radix scutellariae 90g, windproof 105g, glutinous rehmannia 320g, Radix Angelicae Sinensis 120g, evodia rutaecarpa 45g, reticulate millettia 130g, peach Benevolence 120g, safflower 105g, root of Dahurain angelica 105g, Jehol Ligusticum Rhizome 80g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Embodiment 3：

A kind of new medicine composition for treating headache, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows：

Yncaria stem with hooks 350g, Ligusticum wallichii 120g, root of kudzu vine 160g, Chinese ephedra 120g, asarum 100g, RADIX ACONITI LATERALIS PREPARATA 150g, radix bupleuri 120g, the root of herbaceous peony 160g, notopterygium root 260g, levisticum 150g, radix scutellariae 100g, windproof 120g, glutinous rehmannia 360g, Radix Angelicae Sinensis 160g, evodia rutaecarpa 60g, reticulate millettia 160g, peach kernel 160g, safflower 120g, root of Dahurain angelica 120g, Jehol Ligusticum Rhizome 100g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

Model case

Through clinical conditions headache totally 1135, the age is 630 of more than 19 years old, and only 505 are less than 19 years old. 1030 to be fully recovered in 1135 patients, effective 82, invalid 23.Total effective rate is up to 98%.

Claims (3)

1. a kind of new medicine composition for treating headache, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows：

30~350g of yncaria stem with hooks, 30~120g of Ligusticum wallichii, 80~160g of the root of kudzu vine, 30~120g of Chinese ephedra, 15~100g of asarum, RADIX ACONITI LATERALIS PREPARATA 30 It is~150g, 30~120g of radix bupleuri, 60~160g of the root of herbaceous peony, 100~260g of notopterygium root, 30~150g of levisticum, 30~100g of radix scutellariae, windproof 50~120g, 100~360g of glutinous rehmannia, 80~160g of Radix Angelicae Sinensis, 15~60g of evodia rutaecarpa, 100~160g of reticulate millettia, peach kernel 80~ 160g, 30~120g of safflower, 30~120g of the root of Dahurain angelica, 30~100g of Jehol Ligusticum Rhizome, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and starch are fitted Amount.

2. the new medicine composition for the treatment of headache according to claim 1, it is characterised in that the Chinese medicine composition Each component and its mass parts are than as follows：

38~310g of yncaria stem with hooks, 38~105g of Ligusticum wallichii, 90~140g of the root of kudzu vine, 38~105g of Chinese ephedra, 20~90g of asarum, RADIX ACONITI LATERALIS PREPARATA 38 It is~130g, 38~105g of radix bupleuri, 70~140g of the root of herbaceous peony, 115~230g of notopterygium root, 38~130g of levisticum, 38~90g of radix scutellariae, windproof 58~105g, 115~320g of glutinous rehmannia, 90~120g of Radix Angelicae Sinensis, 20~45g of evodia rutaecarpa, 120~130g of reticulate millettia, peach kernel 100~ 120g, 45~105g of safflower, 38~105g of the root of Dahurain angelica, 45~80g of Jehol Ligusticum Rhizome, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and starch are fitted Amount.

3. the new medicine composition of the treatment headache according to claim 1 to 2, it is characterised in that the Chinese traditional medicine composition The each component and its mass parts of thing are than as follows：

Yncaria stem with hooks 280g, Ligusticum wallichii 95g, root of kudzu vine 120g, Chinese ephedra 95g, asarum 80g, RADIX ACONITI LATERALIS PREPARATA 115g, radix bupleuri 95g, root of herbaceous peony 120g, Qiang Work 200g, levisticum 115g, radix scutellariae 80g, windproof 95g, glutinous rehmannia 260g, Radix Angelicae Sinensis 105g, evodia rutaecarpa 40g, reticulate millettia 115g, peach kernel 105g, safflower 95g, root of Dahurain angelica 95g, Jehol Ligusticum Rhizome 70g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.