CN107823090A - A kind of active white skin care solution and preparation method containing ambergris - Google Patents
A kind of active white skin care solution and preparation method containing ambergris Download PDFInfo
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- CN107823090A CN107823090A CN201711272574.4A CN201711272574A CN107823090A CN 107823090 A CN107823090 A CN 107823090A CN 201711272574 A CN201711272574 A CN 201711272574A CN 107823090 A CN107823090 A CN 107823090A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
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- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/84—Products or compounds obtained by lyophilisation, freeze-drying
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Abstract
The invention discloses a kind of shin moisturizer and preparation method of the beauty containing ambergris, belong to technical field of skin care, the weight/mass percentage composition of skin care compositions is 7.6% in skin care item, and skin care compositions includes the component of following mass fraction：1~4 part of 20~26 parts of tree peony stem cell extract, 5~10 parts of Katsumadai seed extract and ambergris.The skin care compositions and shin moisturizer of the present invention is not but not damage skin, and good the effect of beauty.
Description
Technical field
The invention belongs to technical field of skin care, more particularly to a kind of active white skin care solution and preparation method containing ambergris.
Background technology
With the improvement of living standard, more and more people focus on beautifying face and moistering lotion, and cosmetic industry is developed rapidly.Make up
Kind class is various, there is anti-aging, uvioresistant and whitening etc..However, the synthesis chemistry examination added in existing Skin whitening care cosmeticses
Agent is excessive, easily damages skin；Secondly, white-skinned face function is poor.
Therefore, it is necessary to prepare new skin care item, its not but not damage skin, and white-skinned face function is good.
The content of the invention
Present invention aims to overcome that the shortcomings of the prior art, and provide a kind of active white skin care solution containing ambergris and
Preparation method, not but not damage skin, and whitening effect is not good for the shin moisturizer.
To achieve the above object, the technical scheme taken of the present invention is：A kind of skin care compositions of whitening, it includes following
The component of mass fraction：1~4 part of 20~26 parts of tree peony stem cell extract, 5~10 parts of Katsumadai seed extract and ambergris.
Tree peony stem cell extract contains various active composition, such as tree peony polyphenol, can take good care of skin, make skin have bullet
Property.Katsumadai seed extract can suppress the activity of tyrosinase, decompose B16 cell thing.Ambergris can improve skin care compositions
Fragrance, it is adapted to vast consumer groups.
The preparation method of tree peony stem cell extract comprises the following steps：
1) part for tree peony stem is chosen, carry out disinfection processing；Chopping is seeded on MS culture mediums, dark training at 25 DEG C
Support；The outer paraphyte of propagation is taken out after two weeks, separates and is transferred in subculture medium and cultivate, subculture once, obtains every two weeks
To tree peony stem cell；
2) tree peony stem cell is cracked, is freeze-dried afterwards, that is, obtains tree peony stem cell extract.
The skin care compositions of the present invention includes tree peony stem cell extract, Katsumadai seed extract and ambergris, and tree peony is dry thin
Born of the same parents' extract, Katsumadai seed extract and ambergris, can skin care and skin whitenings in the range of certain proportion；And the skin care group
Compound is mostly natural materials, to skin zero damage.
As the improvement of above-mentioned technical proposal, skin care compositions includes the component of following mass fraction：Tree peony stem cell carries
Take 1~2 part of 22~25 parts of thing, 8~10 parts of Katsumadai seed extract and ambergris.
As the further improvement of above-mentioned technical proposal, skin care compositions also includes daisy flower extract.Daisy is extracted
Thing can suppress the generation of melanin, softening epidermal cell, reach good white-skinned face function.
As the further improvement of above-mentioned technical proposal, the mass fraction of the daisy flower extract is 5~8 parts.When
When the mass fraction of daisy flower extract is 5~8 parts, daisy flower extract can significantly improve the work(of the whitening of skin care compositions
Effect.
As the further improvement of above-mentioned technical proposal, skin care compositions is made up of the component of following mass fraction：It is male
5~8 parts of red 22~25 parts of stem cell extract, 8~10 parts of Katsumadai seed extract, 1~2 part of ambergris and daisy flower extract.
As the further improvement of above-mentioned technical proposal, the matter of the Katsumadai seed extract and the daisy flower extract
Amount is than being 1~1.3.When the mass ratio of Katsumadai seed extract and daisy flower extract is 1~1.3, Katsumadai seed extract and young bird
Chrysanthemum extract has collaboration whitening effect.
In addition, the present invention also provides application of the described skin care compositions in shin moisturizer.
In addition, the present invention also provides a kind of shin moisturizer for including described skin care compositions.
As the further improvement of above-mentioned technical proposal, the shin moisturizer is made up of the component of following weight/mass percentage composition：
Skin care compositions 7.6%, emulsifying agent 10.3% and NMF 8%, surplus are deionized water.
In addition, the present invention also provides a kind of preparation method of described shin moisturizer, it comprises the following steps successively：
S1) skin care compositions is added in deionized water, in 69 DEG C of heating stirring 2h, obtains mixture I；
S2 emulsifying agent and NMF) are added into the mixture I, in 53 DEG C of heating stirring 1h, skin care is obtained after cooling
Liquid.
The beneficial effects of the present invention are：The present invention provides a kind of active white skin care solution containing ambergris, skin care of the invention
Tree peony stem cell extract in composition, Katsumadai seed extract, the quality of ambergris and daisy flower extract are in certain proportion model
, can efficiently skin whitening in enclosing；And in said composition and shin moisturizer be mostly natural materials, to skin zero damage；It is in addition, careless
Fructus Amomi Rotundus extract and daisy flower extract can cooperate with whitening.
Embodiment
For the object, technical solutions and advantages of the present invention are better described, below in conjunction with specific embodiment and subordinate list pair
The present invention is described further.
Embodiment 1
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：20 parts of tree peony stem cell extract,
4 parts of 8.9 parts of Katsumadai seed extract and ambergris.
The preparation method of tree peony stem cell extract comprises the following steps in skin care compositions：
1) part for tree peony stem is chosen, carry out disinfection processing；Chopping is seeded on MS culture mediums, dark training at 25 DEG C
Support；The outer paraphyte of propagation is taken out after two weeks, separates and is transferred in subculture medium and cultivate, subculture once, obtains every two weeks
To tree peony stem cell；
2) tree peony stem cell is cracked, is freeze-dried afterwards, that is, obtains tree peony stem cell extract.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it comprises the following steps successively：
S1) skin care compositions is added in deionized water, in 69 DEG C of heating stirring 2h, obtains mixture I；
S2 emulsifying agent and NMF) are added into the mixture I, in 53 DEG C of heating stirring 1h, skin care is obtained after cooling
Liquid.
Embodiment 2
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：Tree peony stem cell extract 24.9
1 part of part, 10 parts of Katsumadai seed extract and ambergris.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Embodiment 3
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：26 parts of tree peony stem cell extract,
3.2 parts of 5 parts of Katsumadai seed extract and ambergris.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Embodiment 4
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：22 parts of tree peony stem cell extract,
5 parts of 8 parts of Katsumadai seed extract, 1 part of ambergris and daisy flower extract.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Embodiment 5
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：Tree peony stem cell extract 24.2
Part, 9 parts of Katsumadai seed extract, 2 parts of ambergris and 6 parts of daisy flower extract.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Embodiment 6
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：25 parts of tree peony stem cell extract,
7 parts of 10 parts of Katsumadai seed extract, 1.2 parts of ambergris and daisy flower extract.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Embodiment 7
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：22 parts of tree peony stem cell extract,
8 parts of 8 parts of Katsumadai seed extract, 1 part of ambergris and daisy flower extract.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Embodiment 8
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：Tree peony stem cell extract 24.2
Part, 9 parts of Katsumadai seed extract, 2 parts of ambergris and 7 parts of daisy flower extract.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Embodiment 9
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：25 parts of tree peony stem cell extract,
8 parts of 10 parts of Katsumadai seed extract, 1.2 parts of ambergris and daisy flower extract.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Comparative example 1
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：Tree peony stem cell extract 14.2
4 parts of part, 8 parts of Katsumadai seed extract and ambergris.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Comparative example 2
A kind of skin care compositions of whitening, it is made up of the component of following mass fraction：30 parts of tree peony stem cell extract,
0.8 part of 9 parts of Katsumadai seed extract and ambergris.
The present embodiment also provides a kind of shin moisturizer, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
7.6%th, emulsifying agent (sorbierite olive grease) 10.3% and NMF (glycerine) 8%, surplus is deionized water.
The preparation method of shin moisturizer described in the present embodiment, it is same as Example 1.
Effect example 1
Choose a number of volunteer, using MEXAMETER MX18 skin pigments instrument using 1 day before shin moisturizer and
Continuous use shin moisturizer determines the melanin content of volunteer's skin of face after 5 weeks, average.The face of volunteer is daily
Early, evening respectively smears a shin moisturizer, without using other active white skin care solutions during test.Measurement result is come with melanin reduced rate
Represent, melanin reduced rate is higher, illustrates that whitening effect is more obvious.The calculation formula of melanin reduced rate is as follows：
Melanin reduced rate=(use melanin after the melanin content-continuous use skin care item 5 weeks of 1 day before skin care item
Content)/use melanin content × 100% of 1 day before skin care item.
500 volunteers, are randomly divided into 5 groups：A1 groups use the shin moisturizer of embodiment 1, and B1 groups use the skin care of embodiment 2
Liquid, C1 groups use the shin moisturizer of embodiment 3, and D1 groups use the shin moisturizer of comparative example 1, and E1 groups use the shin moisturizer of comparative example 2, black
The measurement result of pigment reduced rate is as shown in table 1.
Table 1
| Group | A1 groups | B1 groups | C1 groups | D1 groups | E1 groups |
| Melanin reduced rate/% | 27.6 | 28.2 | 27.2 | 18.2 | 17.0 |
As shown in table 1, the melanin reduced rate of A1, B1 and C1 group is more than the melanin reduced rate of D1 and E1 groups；Thus may be used
See, when the mass fraction of tree peony stem cell in skin care compositions is 20~26 parts, mass fraction in one's early teens is 5~10 parts, dragon
When the fragrant mass fraction of saliva is 1~4 part, the white-skinned face function of skin care compositions and shin moisturizer is preferable.
Effect example 2
With reference to effect example, 1,600 volunteers are randomly divided into 6 groups：A2 groups use the shin moisturizer of embodiment 1, and B2 groups use real
The shin moisturizer of example 2 is applied, C2 groups use the shin moisturizer of embodiment 3, and D2 groups use the shin moisturizer of embodiment 4, and E2 groups use embodiment 5
Shin moisturizer, F2 groups use the shin moisturizer of embodiment 6, and the measurement result of melanin reduced rate is as shown in table 2.
Table 2
| Group | A2 groups | B2 groups | C2 groups | D2 groups | E2 groups | F2 groups |
| Melanin reduced rate/% | 27.6 | 28.2 | 27.2 | 36.3 | 36.5 | 37 |
As shown in table 2, the melanin reduced rate of A2, B2 and C2 group is less than the melanin reduced rate of D2, E2 and F2 group；Thus
It can be seen that when the mass fraction of tree peony stem cell in skin care compositions is 22~25 parts, mass fraction in one's early teens is 8~10 parts,
The mass fraction of ambergris is 1~2 part, when the mass fraction of Daisy is 5~8 parts, the whitening of skin care compositions and shin moisturizer
Effect is good.
Effect example 3
With reference to effect example, 1,600 volunteers are randomly divided into 6 groups：A3 groups use the shin moisturizer of embodiment 4, and B3 groups use real
The shin moisturizer of example 5 is applied, C3 groups use the shin moisturizer of embodiment 6, and D3 groups use the shin moisturizer of embodiment 7, and E3 groups use embodiment 8
Shin moisturizer, F3 groups use the shin moisturizer of embodiment 9, and the measurement result of melanin reduced rate is as shown in table 3.
Table 3
| Group | A3 groups | B3 groups | C3 groups | D3 groups | E3 groups | F3 groups |
| Melanin reduced rate/% | 36.3 | 36.5 | 37 | 46 | 47.2 | 43.5 |
As shown in table 3, the melanin reduced rate of A3, B3 and C3 group is less than the melanin reduced rate of D3, E3 and F3 group；Thus
It can be seen that the mass fraction of tree peony stem cell is 22~25 parts in skin care compositions, mass fraction in one's early teens is 8~10 parts, dragon
The fragrant mass fraction of saliva is 1~2 part, and the mass fraction of Daisy is 5~8 parts, and Katsumadai seed extract and daisy flower extract
Mass ratio be 1~1.3 when, the white-skinned face function of skin care compositions and shin moisturizer is more preferable.
Finally, it should be noted that above example to illustrate technical scheme rather than to the present invention protect
The limitation of scope, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should manage
Solution, technical scheme can be modified or replaced on an equal basis, without departing from technical solution of the present invention essence and
Scope.
Claims (10)
1. a kind of skin care compositions of whitening, it is characterised in that include the component of following mass fraction：Tree peony stem cell extract
1~4 part of 20~26 parts, 5~10 parts of Katsumadai seed extract and ambergris.
2. skin care compositions as claimed in claim 1, it is characterised in that include the component of following mass fraction：Tree peony is dry thin
1~2 part of 22~25 parts of born of the same parents' extract, 8~10 parts of Katsumadai seed extract and ambergris.
3. skin care compositions as claimed in claim 1 or 2, it is characterised in that also comprising daisy flower extract.
4. skin care compositions as claimed in claim 3, it is characterised in that the mass fraction of the daisy flower extract is 5~8
Part.
5. skin care compositions as claimed in claim 4, it is characterised in that be made up of the component of following mass fraction：Tree peony does
5~8 parts of 22~25 parts of cell extract, 8~10 parts of Katsumadai seed extract, 1~2 part of ambergris and daisy flower extract.
6. skin care compositions as claimed in claim 5, it is characterised in that the Katsumadai seed extract extracts with the Daisy
The mass ratio of thing is 1~1.3.
7. application of the composition of skin care in shin moisturizer as described in any one of claim 1~6.
A kind of 8. shin moisturizer for including the skin care compositions as described in power requires 1~6 any one.
9. shin moisturizer as claimed in claim 8, it is characterised in that the shin moisturizer by following weight/mass percentage composition component structure
Into：Skin care compositions 7.6%, emulsifying agent 10.3% and NMF 8%, surplus are deionized water.
10. a kind of preparation method of shin moisturizer as claimed in claim 9, it is characterised in that comprise the following steps successively：
S1) skin care compositions is added in deionized water, in 69 DEG C of heating stirring 2h, obtains mixture I；
S2 emulsifying agent and NMF) are added into the mixture I, in 53 DEG C of heating stirring 1h, shin moisturizer is obtained after cooling.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108721203A (en) * | 2018-08-09 | 2018-11-02 | 广州暨南生物医药研究开发基地有限公司 | Skin care item and preparation method thereof are repaired in a kind of whitening of the extract of stem cell containing tree peony |
| FR3130290A1 (en) | 2021-12-15 | 2023-06-16 | L'oreal | Dedifferentiated plant cells of the genus Paeonia, its extracts and its cosmetic uses |
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| CN104711215A (en) * | 2015-04-09 | 2015-06-17 | 广州赛莱拉干细胞科技股份有限公司 | Apple stem cell culture method and apple stem cells cultured by method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108721203A (en) * | 2018-08-09 | 2018-11-02 | 广州暨南生物医药研究开发基地有限公司 | Skin care item and preparation method thereof are repaired in a kind of whitening of the extract of stem cell containing tree peony |
| FR3130290A1 (en) | 2021-12-15 | 2023-06-16 | L'oreal | Dedifferentiated plant cells of the genus Paeonia, its extracts and its cosmetic uses |
| WO2023110780A1 (en) | 2021-12-15 | 2023-06-22 | L'oreal | Dedifferentiated plant cells of the genus paeonia, extracts thereof and cosmetic uses thereof |
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Application publication date: 20180323 |