CN107773813A - A kind of precharging preparation of the erythropoietin class parenteral solution with safety guard - Google Patents

A kind of precharging preparation of the erythropoietin class parenteral solution with safety guard Download PDF

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Publication number
CN107773813A
CN107773813A CN201610786780.6A CN201610786780A CN107773813A CN 107773813 A CN107773813 A CN 107773813A CN 201610786780 A CN201610786780 A CN 201610786780A CN 107773813 A CN107773813 A CN 107773813A
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CN
China
Prior art keywords
inner cylinder
needle
needle tubing
safety device
outer barrel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610786780.6A
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Chinese (zh)
Inventor
周永春
厉颖
戴素霞
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Chemo Wanbang Biopharma Co Ltd
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Shanghai Chemo Wanbang Biopharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Shanghai Chemo Wanbang Biopharma Co Ltd filed Critical Shanghai Chemo Wanbang Biopharma Co Ltd
Priority to CN201610786780.6A priority Critical patent/CN107773813A/en
Publication of CN107773813A publication Critical patent/CN107773813A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M5/3134Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3257Semi-automatic sleeve extension, i.e. in which triggering of the sleeve extension requires a deliberate action by the user, e.g. manual release of spring-biased extension means

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The present invention relates to medical instruments field, more particularly to a kind of precharging preparation of the erythropoietin class parenteral solution with safety guard.Present invention firstly provides a kind of precharging type syringe with safety device; including safety device; the safety device includes outer barrel and the first inner cylinder being sheathed in outer barrel; first inner cylinder is movably set in outside needle tubing through elastomeric element; the rear end of the outer barrel is provided with needle tubing flange displacement limiting part; first inner cylinder includes Tip protection part, and the outer wall of the first inner cylinder and the inwall of outer barrel, which are correspondingly provided with, to be prevented the first limit assembly of tube rear end abjection outer barrel in first and stop the second limit assembly that the first inner cylinder front end is moved toward syringe needle direction.When erythropoietin class decoction is pre-charged with the needle tubing of the precharging type syringe, the precharging preparation of the erythropoietin class parenteral solution with safety guard is formed.The present invention can eject after the completion of injection by setting safety device, protect syringe needle not injure medical personnel and patient.

Description

A kind of precharging preparation of the erythropoietin class parenteral solution with safety guard
Technical field
The present invention relates to medical instruments field, more particularly to a kind of erythropoietin class parenteral solution with safety guard Precharging preparation.
Background technology
Erythropoietin class product has two kinds of formulations of parenteral solution and freeze-dried powder on current domestic medical market, uses cillin bottle bag Dress or pre-filled packaging, the bottled product in XiLin are packed, it is necessary to first open, then aspirated again with syringe, so when in use Easily cause secondary pollution.The syringe needle of syringe is also easy to produce liquor residue with the dead space of needle tubing junction, and usage amount is inaccurate. Other conventional needle hypodermic injection area is big, patient pain is felt increase.Equally, powder pin need to be added after liquid redissolves and used, The problem of same can be produced.
Precharging type syringe is the inner packing using precharging type syringe as product, it be will injection medicine directly it is filling In pre-filled needle tubing, and injection needle is installed on needle tubing, syringe and decoction packing container are combined into one, it is direct during use Injection, it is very convenient.Precharging type syringe is as a kind of interior packaging material for directly contacting medicine, with traditional packaging material (cillin bottle or peace Small jar is packed) compare, it is safer convenient.
But precharging type syringe in the market does not install safety device, the syringe needle of precharging type syringe holds Medical personnel and patient easily are stabbed, infection risk is higher.
The content of the invention
In view of the above the shortcomings that prior art, the technical problem to be solved in the present invention is that providing a kind of band safety protects The precharging preparation of the erythropoietin class parenteral solution of protection unit.Safety device can eject after the completion of injection, protect syringe needle not Injure medical personnel and patient.
In order to achieve the above objects and other related objects, the present invention adopts the following technical scheme that:
Present invention firstly provides a kind of precharging type syringe with safety device, including needle tubing, piston, syringe needle, pin Head helmet and push rod, needle tubing are the hollow circular cylinder of opening, are fixed with syringe needle on the conehead of needle tubing front end, syringe needle is socketed on syringe needle Helmet, needle-covering cap is interior to be provided with the seal rubber plug supporting with syringe needle, is provided with a piston in needle tubing, piston is connected with push rod, described The rear end of needle tubing is provided with needle tubing flange;The precharging type syringe also includes safety device, the safety device bag Outer barrel and the first inner cylinder being sheathed in outer barrel are included, first inner cylinder is movably set in outside the needle tubing through elastomeric element, institute The rear end for stating outer barrel is provided with needle tubing flange displacement limiting part, and first inner cylinder includes Tip protection part, the first inner cylinder The inwall of outer wall and outer barrel, which is correspondingly provided with, to be prevented the first limit assembly of tube rear end abjection outer barrel in first and stops the first inner cylinder The second limit assembly that front end is moved toward syringe needle direction.
Preferably, first limit assembly includes the first limiting section being located on first inner tank theca, described outer The inwall of cylinder is provided with inwardly protruded second limiting section.
Preferably, first limiting section is provided with multiple, and along the circumferential direction uniformly arrangement.
Preferably, second limit assembly includes being located at the first clamping of outwardly convex on the outer wall of first inner cylinder Portion and the second card-tight part positioned at the outer cylinder front end, first card-tight part and the second card-tight part Elastic Contact.
Preferably, second card-tight part is provided with multiple grooves, and multiple grooves are along the circumferential direction distributed.
Preferably, the elastomeric element is spring to precharging type syringe, and the spring is looped around the outer of first inner cylinder On wall.
Preferably, the second inner cylinder is provided with the outer barrel, second inner cylinder is fixed on the needle tubing flange displacement limitation On part, neck is provided with second inner cylinder, one end of the elastomeric element is fixed on the neck.
Preferably, the rear end of the outer barrel is provided with fixed mount, and the fixed mount is fixed on the needle tubing flange displacement limitation On part, the flange is between the fixed mount and the needle tubing flange displacement limiting part.
Preferably, the needle diameter is 0.2~0.5mm, and the needle point of syringe needle is double inclined plane, three inclined-planes or five inclined-planes.
Preferably, the needle tubing volume is 1ml, 2ml, 2.25ml, 2.5ml, 3ml or 5ml.
Preferably, the needle-covering cap outer surface is provided with anti-slip veins.
Preferably, erythropoietin class decoction, the erythropoietin class decoction choosing are pre-charged with the needle tubing of the precharging type syringe From Recombinant Human Erythropoietin, Recombinant Human Erythropoietin-heterozygosis Fc fusion proteins, Recombinant Human Erythropoietin-Fc fusion proteins, change configuration restructuring The carbamylation derivative of people's erythropoietin, Pegylation Recombinant Human Erythropoietin or Recombinant Human Erythropoietin, form band safeguard protection The precharging preparation of the erythropoietin class parenteral solution of device.
As described above, precharging type syringe of the present invention and the erythropoietin class parenteral solution with safety guard is pre- Formula preparation is filled, is had the advantages that:Medical care is extremely easy to use, without suction, without installing syringe needle, reduces the note of patient Penetrate cost;
1st, avoid, using the generation aspirated repeatedly after dilution and cause plug to be considered to be worth doing, reducing residual and secondary pollution chance;
2nd, design, can be fully utilized without dead space, noresidue decoction, dosage is more accurate;
3rd, Unit Dose Volume is small, and distending pain sense is lighter during injection;
4th, syringe needle is sharp keen, convenient operation, reduces tingling sensation;
5th, it is disposable, direct injection, pollution risk is reduced, increase the drug safety of patient;
6th, after the completion of injecting, safety device is artificially excited, after inner cylinder ejection, injection needle is entangled completely, can effectively protect The risk that medical personnel infect from acupuncture.
Brief description of the drawings
Fig. 1 is the structural representation when present invention does not excite.
Fig. 2 is the structural representation after the present invention excites.
Fig. 3 is the planar structure schematic diagram of the second card-tight part.
Component label instructions
10 needle tubings
11 pistons
12 syringe needles
13 needle-covering caps
14 push rods
15 needle tubing flanges
20 safety devices
30 outer barrels
31 needle tubing flange displacement limiting parts
311 through holes
32 second limiting sections
33 fixed mounts
40 first inner cylinders
400 Tip protection parts
41 first limiting sections
42 first card-tight parts
43 second card-tight parts
431 grooves
50 elastomeric elements
60 second inner cylinders
61 necks
Embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation Content disclosed by book understands other advantages and effect of the present invention easily.
It should be clear that structure, ratio, size depicted in this specification institute accompanying drawings etc., only coordinating specification to be taken off The content shown, so that those skilled in the art understands and reads, the enforceable qualifications of the present invention are not limited to, therefore Do not have technical essential meaning, the modification of any structure, the change of proportionate relationship or the adjustment of size, do not influenceing the present invention Under the effect of can be generated and the purpose that can reach, it all should still fall the scope that can cover in disclosed technology contents It is interior.Meanwhile cited such as " on ", " under ", "left", "right", the term of " centre " in this specification, it is merely convenient to describe Understand, and be not used to limit the enforceable scope of the present invention, its relativeness is altered or modified, and technology is being changed without essence Inside hold, when being also considered as the enforceable category of the present invention.
As depicted in figs. 1 and 2, a kind of precharging type syringe with safety device of present invention offer, including needle tubing 10, Piston 11, syringe needle 12, needle-covering cap 13 and push rod 14, needle tubing 10 is the hollow circular cylinder of opening, on the conehead of the front end of needle tubing 10 Syringe needle 12 is fixed with, is removably socketed needle-covering cap 13 on syringe needle 12, is provided with needle-covering cap 13 and supporting close of syringe needle 12 Sealing plug, be provided with capping of the piston 11 as needle tubing herb liquid in needle tubing, can slide and seal in needle tubing, piston 11 with Push rod 14 connects, and push rod 14 has one section to be inserted into needle tubing, can be moved with piston 11 in needle tubing, the rear end of the needle tubing 10 Provided with needle tubing flange 15.
As shown in Figure 1 to Figure 3, the precharging type syringe also includes safety device 20, the safety device Including outer barrel 30 and the first inner cylinder 40 being sheathed in outer barrel 30, first inner cylinder 40 is movably set in institute through elastomeric element 50 State outside needle tubing 10, the rear end of the outer barrel 30 is provided with needle tubing flange displacement limiting part 31, the needle tubing flange displacement limiting unit Part 31 is provided with through hole 311, and the needle tubing flange displacement limiting part 31 can be used for stopping the needle tubing flange 15, prevent described Needle tubing flange 15 enters in the outer barrel 30.First inner cylinder 40 includes Tip protection part 400, the bullet of the first inner cylinder 40 When going out, the Tip protection part 400 is enclosed on the periphery of the syringe needle 12, the outer wall of the first inner cylinder 40 and the inwall pair of outer barrel 30 Should be provided with prevents the first limit assembly of tube rear end abjection outer barrel in first and stops that the front end of the first inner cylinder 40 is transported toward syringe needle direction The second dynamic limit assembly, first limit assembly ensure that when first inner cylinder 40 ejects the outer barrel 30 will not be left. When not exciting, the rear end of first inner cylinder 40 contacts through the through hole 311 with the needle tubing flange 15, front end with it is described outer The first inner cylinder 40 is stated in 30 Elastic Contacts of cylinder, the front end of the outer barrel 30 by elastic card residence, and second limit assembly ensures In the case of no applied external force, first inner cylinder 40 will not move forward.The elastomeric element 50 is positioned at described the Between one inner cylinder 40 and the outer barrel 30, the elastomeric element 50 applies elastic force to the first limiting section 41, so that described first Inner cylinder 40 by active force forward, but due to the active force be less than outer barrel 30 front end by fettering first inner cylinder 40 Active force, first inner cylinder 40 is not moved forward in the presence of no external thrust.
Preferably, first limit assembly includes the first limiting section 41 being located on the outer wall of the first inner cylinder 40, institute The inwall for stating outer barrel 30 is provided with inwardly protruded second limiting section 32.Preferably, first limiting section 41 is provided with multiple, and Along the circumferential direction uniformly arrangement.After when the present invention excites, first limiting section 41 is moved to the front end of the outer barrel 30, this Shi Houduan the second limiting section 32 can block first limiting section 41, be moved after preventing first inner cylinder 40, further really Protect the security used.Preferably, the elastomeric element 50 is spring, and the spring is looped around the outer wall of first inner cylinder 40 On.Preferably, the second inner cylinder 60 is provided with the outer barrel 30, second inner cylinder 60 is fixed on the needle tubing flange displacement limitation On part 31, neck 61 is provided with second inner cylinder 60, one end of the elastomeric element 60 is fixed on the neck 61.
As shown in Figure 1 to Figure 3, it is preferable that second limit assembly includes being located on the outer wall of first inner cylinder 40 First card-tight part 42 of outwardly convex and the second card-tight part 43 positioned at the front end of outer barrel 30, first card-tight part 42 With the Elastic Contact of the second card-tight part 43.The second card-tight part 43 states the first card by elastic card residence described in precharging type syringe Tight portion 42, it is ensured that the first inner cylinder 40 will not eject described in when not exciting, and when exciting the present invention, experimenter firmly pushes away forward institute Push rod 14 is stated, the needle tubing flange 15 promotes forward first inner cylinder 40 to move forward, and first card-tight part 42 is detached institute The elastic force constraint of the second card-tight part 43 is stated, first inner cylinder 40 is ejected forward due to the elastic force effect of the elastomeric element 50. Preferably, second card-tight part 43 is provided with multiple grooves 431, and multiple grooves 431 are along the circumferential direction distributed, it is ensured that institute Stating the first inner cylinder 40 can smoothly eject.
Preferably, the rear end of the outer barrel 30 is provided with fixed mount 33, and the fixed mount 33 is fixed on the needle tubing flange position Move on limiting part 31, the needle tubing flange 15 be located at the fixed mount 33 and the needle tubing flange displacement limiting part 31 it Between.Preferably, 12 a diameter of 0.2~0.5mm of syringe needle, the needle point of syringe needle using it is most thin, most sharp for double inclined plane, it is three oblique Face or five inclined-planes, patient only has slight sensation during injection.Preferably, needle tubing uses borosilicate glass material, and piston uses Butyl material, the selection of the material can reduce the absorption of decoction.Preferably, the volume of needle tubing 10 be 1ml, 2ml, 2.25ml, 2.5ml, 3ml or 5ml, according to medical treatment and the market demand, new specification can also be increased.Due to facing for various decoctions The bed amount of recommending is different, also caused by patient's individual difference in itself usage amount difference, erythropoietin class medicine of the invention The specification of the precharging type syringe of thing can be diversified.
The precharging type syringe of the present invention passes through sterilization treatment, different under the conditions of local laminar flow after detection The precharging type syringe distinguishes filling Recombinant Human Erythropoietin parenteral solution, Recombinant Human Erythropoietin-heterozygosis Fc fusion proteins, recombined human Erythropoietin-Fc fusion proteins, change configuration Recombinant Human Erythropoietin, and Pegylation Recombinant Human Erythropoietin parenteral solution and recombined human promote In the cavity that the carbamylation derivative injection of red pigment surrounds to needle tubing, conehead and piston, every kind of decoction difference is filling 1000IU, 2000IU, 3000IU, 4000IU, 5000IU, 6000IU, 10000IU, 20000IU, 40000IU, 0.1mg, 0.2mg, 0.3mg, 0.4mg, 0.5mg, 0.6mg, 1.0mg, 1.5mg, it is whole to load in safety device after the completion of filling, then use Aluminium foil or bubble-cap type encapsulation, form the precharging preparation of the erythropoietin class parenteral solution with safety guard.Band safeguard protection fills The filling of precharging preparation for the erythropoietin class parenteral solution put, lamp inspection, labeling, stubborn bar, loading safety device, plastic packaging use certainly Dynamic production line is completed.
Through trial-production, precharging type syringe of this kind with safety guard and the erythropoietin class note with safety guard The precharging preparation of liquid is penetrated, it is easy to use, the risk of clinical infection can be effectively reduced, there is good potential applicability in clinical practice.
In summary, the present invention effectively overcomes various shortcoming of the prior art and has high industrial utilization.
The above-described embodiments merely illustrate the principles and effects of the present invention, not for the limitation present invention.It is any ripe Know the personage of this technology all can carry out modifications and changes under the spirit and scope without prejudice to the present invention to above-described embodiment.Cause This, those of ordinary skill in the art is complete without departing from disclosed spirit and institute under technological thought such as Into all equivalent modifications or change, should by the present invention claim be covered.

Claims (10)

1. a kind of precharging type syringe with safety device, including needle tubing (10), piston (11), syringe needle (12), syringe needle shield Cap (13) and push rod (14), needle tubing (10) are the hollow circular cylinder of opening, and syringe needle is fixed with the conehead of needle tubing (10) front end (12) needle-covering cap (13), is socketed on syringe needle (12), the seal rubber plug supporting with syringe needle (12), pin are provided with needle-covering cap (13) A piston (11) is provided with pipe (10), piston (11) is connected with push rod (14), it is characterised in that the rear end of the needle tubing (10) is set There is needle tubing flange (15);The precharging type syringe also includes safety device (20), and the safety device includes outer Cylinder (30) and the first inner cylinder (40) being sheathed in outer barrel (30), first inner cylinder (40) are slidingly connected through elastomeric element (50) In the needle tubing (10) outside, the rear end of the outer barrel (30) is provided with needle tubing flange displacement limiting part (31), first inner cylinder Including Tip protection part (400), the outer wall of the first inner cylinder (40) and the inwall of outer barrel (30), which are correspondingly provided with, prevents the first inner cylinder The second limit assembly that first limit assembly of rear end abjection outer barrel and stop the first inner cylinder (40) front end are moved toward syringe needle direction.
2. the precharging type syringe according to claim 1 with safety device, it is characterised in that:Described first is spacing Component includes being located at the first limiting section (41) on the first inner cylinder (40) outer wall, the inwall of the outer barrel (30) be provided with to The second limiting section (32) of internal projection.
3. the precharging type syringe according to claim 2 with safety device, it is characterised in that:Described first is spacing Portion (41) be provided with it is multiple, and along the circumferential direction uniformly arrangement.
4. the precharging type syringe according to claim 1 with safety device, it is characterised in that:Described second is spacing Component includes being located on the outer wall of first inner cylinder (40) the first card-tight part (42) of outwardly convex and positioned at the outer barrel (30) the second card-tight part (43) of front end, first card-tight part (42) and the second card-tight part (43) Elastic Contact.
5. the precharging type syringe according to claim 4 with safety device, it is characterised in that:Second clamping Portion (43) is provided with multiple grooves (431), and multiple grooves (431) are along the circumferential direction distributed.
6. the precharging type syringe according to claim 1 with safety device, it is characterised in that:The elastomeric element (50) it is spring, the spring is looped around on the outer wall of first inner cylinder (40).
7. the precharging type syringe according to claim 1 with safety device, it is characterised in that:The outer barrel (30) The second inner cylinder (60) is inside provided with, second inner cylinder (60) is fixed on the needle tubing flange displacement limiting part (31), described Neck (61) is provided with second inner cylinder (60), one end of the elastomeric element (60) is fixed on the neck (61).
8. the precharging type syringe according to claim 1 with safety device, it is characterised in that:The outer barrel (30) Rear end be provided with fixed mount (33), the fixed mount (33) is fixed on the needle tubing flange displacement limiting part (31), described Needle tubing flange (15) is located between the fixed mount (33) and the needle tubing flange displacement limiting part (31).
9. the precharging type syringe according to claim 1 with safety device, it is characterised in that:Also include following special Any one of sign is multinomial:1) a diameter of 0.2~0.5mm of the syringe needle (12), the needle point of syringe needle is double inclined plane, three inclined-planes or five Inclined-plane;2) needle tubing (10) volume is 1ml, 2ml, 2.25ml, 2.5ml, 3ml or 5ml;3) needle-covering cap (13) appearance Face is provided with anti-slip veins.
10. the precharging type syringe according to claim 1 with safety device, it is characterised in that:It is described pre-filled Erythropoietin class decoction is pre-charged with the needle tubing (10) of syringe, the erythropoietin class decoction is selected from Recombinant Human Erythropoietin, recombined human Erythropoietin-heterozygosis Fc fusion proteins, Recombinant Human Erythropoietin-Fc fusion proteins, changes configuration Recombinant Human Erythropoietin, Pegylation weight The carbamylation derivative of group people's erythropoietin or Recombinant Human Erythropoietin.
CN201610786780.6A 2016-08-31 2016-08-31 A kind of precharging preparation of the erythropoietin class parenteral solution with safety guard Pending CN107773813A (en)

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CN109364334A (en) * 2018-09-28 2019-02-22 黄桂庭 A kind of syringe
CN111888581A (en) * 2020-09-10 2020-11-06 苏州赛卫生物科技有限公司 Safety syringe with needle protector

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CN104027875A (en) * 2009-05-05 2014-09-10 萨克哈拉姆·D·马赫卡 Universal Safe Syringe
CN201453776U (en) * 2009-06-18 2010-05-12 李炜平 Split pre-filled syringe
CN202589946U (en) * 2011-12-14 2012-12-12 上海凯茂生物医药有限公司 Pre-charging type preparation of heparin type injection
CN103239780A (en) * 2012-02-14 2013-08-14 上海双鸽实业有限公司 Safety syringe needle
CN102631729A (en) * 2012-04-17 2012-08-15 山东新华安得医疗用品有限公司 Disposable safety syringe
CN204709541U (en) * 2015-05-11 2015-10-21 上海聚民生物科技有限公司 A kind of entry needle with protective sleeve
CN206454076U (en) * 2016-08-31 2017-09-01 上海凯茂生物医药有限公司 Precharging type syringe with safety device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109364334A (en) * 2018-09-28 2019-02-22 黄桂庭 A kind of syringe
CN111888581A (en) * 2020-09-10 2020-11-06 苏州赛卫生物科技有限公司 Safety syringe with needle protector

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