CN107751557A - A kind of Chinese herb feed additive for reducing egg cholesterol and its application - Google Patents
A kind of Chinese herb feed additive for reducing egg cholesterol and its application Download PDFInfo
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- CN107751557A CN107751557A CN201610693450.2A CN201610693450A CN107751557A CN 107751557 A CN107751557 A CN 107751557A CN 201610693450 A CN201610693450 A CN 201610693450A CN 107751557 A CN107751557 A CN 107751557A
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Abstract
The Chinese herb feed additive of cholesterol and its application in egg are reduced the invention discloses a kind of, belongs to additive for farm animal feed technical field.Its constituent of described Chinese herb feed additive and parts by weight are：20 40 parts of cassia seed, 30 50 parts of lotus leaf, 30 50 parts of hawthorn, 10 30 parts of the red sage root, 5 20 parts of honeysuckle, 5 20 parts of Ilex Latifolia Thunb, 5 20 parts of ginkgo biloba p.e, 10 30 parts of oriental wormwood；The Chinese herb feed additive safety and environmental friendliness, cost is relatively low, and in being tested applied to laying hen, result of the test is shown：The cholesterol level in laying hen blood and in egg can be significantly reduced.
Description
Technical field
The present invention relates to a kind of Chinese herbal feed additive, and in particular to a kind of Chinese herbal medicine for reducing cholesterol in egg adds
Add agent and its application.
Background technology
One of the main source of egg as protein in human diet, there is very high nutritive value, research shows, people
The intake of the daily cholesterol of body should be less than 300mg, and the content of cholesterol is 200~300mg/ pieces in egg, is food courage
The important sources of sterol, high content cholesterol can cause cholesterol in serum is horizontal to improve in meals, and increase eater suffers from artery
Hardening and the risk of coronary heart disease, therefore, also there is the amount of eating that expert advice should limit egg.
The research for reducing egg cholesterol is increasingly subject to pay attention to, and from 1970s, domestic and foreign scholars pass through heredity selection, egg
The methods of chicken diet changes, feeding cholesterol-lowering drug, numerous studies are carried out to the method for reducing Egg cholesterol amount, passed through
Research shows, carries out the screening in more generations by diversity, and the cholesterol in egg can only at most reduce by 8%, and other method also is difficult to drop
Cholesterol level in low egg.
Chinese herbal medicine is the distinctive traditional Chinese medical theory in China and the product of practice, has enhancing animal body immunity function and resists
Sick ability, have the advantages that to improve production performance and meat Egg Quality flavor, noresidue, be not likely to produce drug resistance.
The content of the invention
In order to overcome the above-mentioned deficiencies of the prior art, the invention provides a kind of Chinese herbal medicine for reducing egg cholesterol to add
Add agent, by applying in laying hen produces, can both ensure that food security, can effectively reduce the content of cholesterol in egg again.
The technical solution adopted in the present invention is：
A kind of Chinese herb feed additive for reducing cholesterol content in eggs is provided, is made up of following medicine：Cassia seed, lotus
Leaf, hawthorn, the red sage root, honeysuckle, Ilex Latifolia Thunb, ginkgo biloba p.e, oriental wormwood.
Composition and the weight ratio of its Chinese medicine composition is：Cassia seed 20-40 parts, lotus leaf 30-50 parts, hawthorn 30-50 parts are red
Join 10-30 parts, honeysuckle 5-20 parts, Ilex Latifolia Thunb 5-20 parts, ginkgo biloba p.e 5-20 parts, oriental wormwood 10-30 parts.
Preferable Chinese herb feed additive prescription, it is characterised in that its constituent and parts by weight are：30 parts of cassia seed, lotus leaf 40
Part, 40 parts of hawthorn, 20 parts of the red sage root, 10 parts of honeysuckle, 10 parts of Ilex Latifolia Thunb, 10 parts of ginkgo biloba p.e, 20 parts of oriental wormwood.
The extracting method of above-mentioned ginkgo biloba p.e uses enzymatic isolation method, ginkgo leaf is dried in 50~60 DEG C of baking ovens, powder
It is broken, 24 mesh sieves are crossed, it is standby to collect powder.Weigh 0.1g cellulases to put in 2000ml beakers, add the dissolving of 1000ml purified waters,
Put in 37 DEG C of constant water bath box, precision weighs Ginkgo Leaf 120g and added in cellulase solution, after sealing, at this temperature
Digest 2h.Take enzymolysis liquid to filter, discard filtrate, residue presses 1:3 add 70% ethanol surname extraction 2h, and ethanol is concentrated under reduced pressure into
Volume is about 50ml, with 3 extractions of the petroleum ether of equivalent point, collects subnatant, adds 2 extractions of n-butanol point of equivalent,
Subnatant is taken to be concentrated under reduced pressure to obtain ginkgo biloba p.e.
It is a kind of reduce egg cholesterol Chinese herb feed additive its preparation method be：By cassia seed, lotus leaf, hawthorn, pellet
After ginseng, honeysuckle, Ilex Latifolia Thunb, oriental wormwood are according to aforementioned proportion precise, after being crushed to 60 mesh respectively, powder is well mixed to obtain,
Ginkgo biloba p.e is added in powder, is crushed to 100 mesh, is produced after well mixed.
Consolidate present invention also offers a kind of Chinese herb feed additive for reducing cholesterol content in eggs in reduction egg courage
Application process in alcohol content, addition weight ratio of the Chinese herb feed additive in egg feedstuff is 1%-3%.
Each bulk drug effect is summarized as follows：
Cassia seed described in this patent, clears liver and improve vision, and sharp water defaecation, there is the effect of laxative action, reducing blood pressure and blood fat.
Lotus leaf described in this patent, contain a variety of alkaloids such as nuciferine, miltanthin and Nuciferine and vitamin C, more
Sugar, there are good reducing blood lipid, norcholesterol；
Hawthorn described in this patent, it can improve and promote Cholesterol Excretion and reduce blood fat, prevent the generation of high fat of blood；
The red sage root described in this patent, the function with blood coagulation system inside and outside anti-platelet aggregation, reduction blood viscosity and regulation；
Honeysuckle described in this patent, there is the effect of reducing cholesterol level in blood plasma；
Ilex Latifolia Thunb described in this patent, containing the trace element such as several amino acids needed by human, vitamin and zinc, manganese, rubidium,
There is reducing blood lipid；
Ginkgo leaf described in this patent, is a kind of plant with very high medical value, and ginkgo biloba extract is flowable powder
End, there is very strong removing free radical and antioxidation；
Oriental wormwood described in this patent, there is cholagogic, liver function protecting is antipyretic, anti-inflammatory, reducing blood lipid, decompression, the effect such as coronary dilatation；
The beneficial effects of the invention are as follows：
（1）Feed addictive of the present invention can improve the egg laying performance of laying hen；
（2）Feed addictive of the present invention can significantly reduce the cholesterol level in egg；
（3）Feed addictive of the present invention safely, effectively, green, have no toxic side effect.
Embodiment
The present invention will be further elaborated by embodiment below, the example is only that a present invention part is real
Example, rather than whole embodiments are applied, therefore the scope of the present invention is not limited to the content.
Embodiment 1：
（1）The formula of the Chinese herb feed additive of this reduction egg cholesterol is：20 parts of cassia seed, 45 parts of lotus leaf, 35 parts of hawthorn are red
25 parts of ginseng, 10 parts of honeysuckle, 15 parts of Ilex Latifolia Thunb, 20 parts of ginkgo biloba p.e, 20 parts of oriental wormwood；
（2）The formula of the Chinese herb feed additive of this reduction egg cholesterol is：35 parts of cassia seed, 35 parts of lotus leaf, 30 parts of hawthorn are red
15 parts of ginseng, 15 parts of honeysuckle, 5 parts of Ilex Latifolia Thunb, 15 parts of ginkgo biloba p.e, 15 parts of oriental wormwood；
（3）The formula of the Chinese herb feed additive of this reduction egg cholesterol is：20 parts of cassia seed, 40 parts of lotus leaf, 35 parts of hawthorn are red
15 parts of ginseng, 5 parts of honeysuckle, 10 parts of Ilex Latifolia Thunb, 20 parts of ginkgo biloba p.e, 30 parts of oriental wormwood；
（4）The formula of the Chinese herb feed additive of this reduction egg cholesterol is：30 parts of cassia seed, 30 parts of lotus leaf, 40 parts of hawthorn are red
10 parts of ginseng, 15 parts of honeysuckle, 10 parts of Ilex Latifolia Thunb, 20 parts of ginkgo biloba p.e, 20 parts of oriental wormwood；
（5）The formula of the Chinese herb feed additive of this reduction egg cholesterol is：25 parts of cassia seed, 50 parts of lotus leaf, 30 parts of hawthorn are red
20 parts of ginseng, 15 parts of honeysuckle, 20 parts of Ilex Latifolia Thunb, 15 parts of ginkgo biloba p.e, 25 parts of oriental wormwood；
（6）The formula of the Chinese herb feed additive of this reduction egg cholesterol is：30 parts of cassia seed, 45 parts of lotus leaf, 50 parts of hawthorn are red
20 parts of ginseng, 10 parts of honeysuckle, 10 parts of Ilex Latifolia Thunb, 15 parts of ginkgo biloba p.e, 25 parts of oriental wormwood；
（7）The formula of the Chinese herb feed additive of this reduction egg cholesterol is：40 parts of cassia seed, 30 parts of lotus leaf, 45 parts of hawthorn are red
30 parts of ginseng, 20 parts of honeysuckle, 20 parts of Ilex Latifolia Thunb, 10 parts of ginkgo biloba p.e, 10 parts of oriental wormwood；
Embodiment 2：
Chinese herb feed additive formula described in embodiment 1, its preparation method are：The extracting method of ginkgo biloba p.e uses enzyme
Solution, ginkgo leaf is dried in 50~60 DEG C of baking ovens, crushed, cross 24 mesh sieves, it is standby to collect powder.Weigh 0.1g cellulases
Put in 2000ml beakers, add the dissolving of 1000ml purified waters, put in 37 DEG C of constant water bath box, precision weighs Ginkgo Leaf 120g
Add in cellulase solution, after sealing, digest 2h at this temperature.Take enzymolysis liquid to filter, discard filtrate, residue presses 1:3 add
Enter 70% ethanol surname extraction 2h, it is about 50ml that ethanol, which is concentrated under reduced pressure into volume, with 3 extractions of the petroleum ether of equivalent point, is collected
Subnatant, points of 2 times extractions of n-butanol of equivalent are added, take subnatant to be concentrated under reduced pressure to obtain ginkgo biloba p.e.
By cassia seed, lotus leaf, hawthorn, the red sage root, honeysuckle, Ilex Latifolia Thunb, oriental wormwood according to aforementioned proportion precise after, respectively
After being crushed to 60 mesh, powder is well mixed to obtain, ginkgo biloba p.e is added in powder, is crushed to 100 mesh, after being well mixed i.e.
.
Embodiment 3：
Application in laying hen：
By the formula Chinese medicine in embodiment 1 according to the preparation method in embodiment 2, after being prepared into Chinese herb feed additive finished product, divide
It is not added to the addition of feed 2% per ton in laying hens essential ration.Select 40 week old Luo Man similar in laying rate and body weight brown
Shell egg laying hen 480, it is grouped using single-factor completely randomized design, experiment is divided into 8 groups, and every group is set to 3 repetitions, each to repeat
20.Wherein test 1 group and be set to control group, feed basal diet, experiment 2-8 groups are respectively in basal diet according to embodiment 1
In（1）-（7）Described prescription, test chicken use cage, according to normal layer breeding management, free choice feeding drinking-water, test prerun
1 week phase, formal 6 weeks phases.The influence of Medical Herb Supplement in Layer Dietary on Cholesterol Content of Egg is shown in Table 1.
The influence of the Medical Herb Supplement in Layer Dietary on Cholesterol Content of Egg of table 1
Chinese herb feed additive can significantly reduce yolk weight cholesterol level and cholesterol content in eggs.
Embodiment 4：
（1）The composition of the Chinese herb feed additive of this reduction egg cholesterol matches：By 20 parts of cassia seed, lotus leaf 30
Part, 30 parts of hawthorn, 10 parts of the red sage root, 5 parts of honeysuckle, 5 parts of Ilex Latifolia Thunb, 10 parts of oriental wormwood, in proportion after precise, it is crushed to respectively
After 60 mesh, powder is well mixed to obtain, according to the extracting method of ginkgo leaf in embodiment 2, by 5 parts of addition powder of ginkgo biloba p.e
In end, 100 mesh are crushed to, are produced after well mixed.According to the addition of feed per ton addition 1%, it is added in layer dietses.
（2）The composition of the Chinese herb feed additive of this reduction egg cholesterol matches：30 parts of cassia seed, lotus leaf 40
Part, 40 parts of hawthorn, 20 parts of the red sage root, 10 parts of honeysuckle, 10 parts of Ilex Latifolia Thunb, 20 parts of oriental wormwood；By above-mentioned Chinese medicine precise in proportion
Afterwards, after being crushed to 60 mesh respectively, powder is well mixed to obtain, according to the extracting method of ginkgo leaf in embodiment 2, ginkgo leaf is carried
10 parts of thing is taken, adds in powder, is crushed to 100 mesh, is produced after well mixed.According to the addition of feed per ton addition 2%, add
It is added in layer dietses.
（3）The composition of the Chinese herb feed additive of this reduction egg cholesterol matches：40 parts of cassia seed, 50 parts,
50 parts of hawthorn, 30 parts of the red sage root, 20 parts of honeysuckle, 20 parts of Ilex Latifolia Thunb, 30 parts of oriental wormwood；After above-mentioned Chinese medicine in proportion precise,
After being crushed to 60 mesh respectively, powder is well mixed to obtain, according to the extracting method of ginkgo leaf in embodiment 2, ginkgo leaf is extracted
20 parts of thing, add in powder, be crushed to 100 mesh, produced after well mixed.According to the addition of feed per ton addition 3%, addition
Into layer dietses.
Application study in laying hen：
The brown shell egg laying hens of 40 week old Luo Man 400 similar in laying rate and body weight are selected, using single-factor completely randomized design point
Group, experiment are divided into 4 groups, and every group is set to 4 repetitions, each to repeat 25.Wherein test I group and be set to control group, feed basic day
Grain, II, III, IV group of experiment is respectively in basal diet according in embodiment 4（1）（2）（3）At described prescription and addition
Reason, test chicken use cage, according to normal layer breeding management, free choice feeding drinking-water, test 1 week preliminary trial period, formal 6 weeks phases.
（1）Influence of the Chinese herb feed additive to performance in layers
After off-test, in units of repetition, record egg production, egg size is weighed, count a feed consumption rate weekly, calculate experimental period
Laying rate, feedstuff-egg ratio, influence of the statistics Chinese herb feed additive to performance in layers, result of the test is as shown in table 1, from table 1
Understand, Chinese herbal medicine can improve the laying rate of laying hen, increase egg size, reduce feedstuff-egg ratio, can improve the production performance of laying hen.
Influence of the Chinese herb feed additive of table 2 to performance in layers
| Group | Laying rate（%） | Egg size（g） | Feed consumption rate（g） | Feedstuff-egg ratio |
| Test I group | 90.75±1.32 | 62.03±1.41 | 126.75±2.08 | 2.04±0.03 |
| Test II group | 91.59±1.02 | 63.74±0.84 | 129.00±0.62 | 2.03±0.22 |
| Test III group | 92.21±0.88 | 64.39±0.60 | 129.69±1.40 | 2.03±0.38 |
| Test IV group | 92.83±0.89 | 64.39±1.32 | 128.92±2.91 | 2.02±0.35 |
（2）Influence of the Chinese herb feed additive to Laying-hen Serum biochemical indicator
After off-test, often repeating to randomly select 3 laying hens, wing venous blood sampling 5ml, 4 DEG C stand 24h, centrifugation（4000r,
20min）After separate serum, the kit measurement provided using Zhong Shengbeikong biotechnologies joint-stock company, testing index includes total
Cholesterol level, content of triglyceride, low-density lipoprotein content, hdl concentration, result of the test are shown in Table 2, from table 1
In understand, Chinese herb feed additive can significantly reduce T-CHOL in Laying-hen Serum, triglycerides and low-density lipoprotein content, show
The hdl concentration improved in Laying-hen Serum is write, total cholesterol level highest can reduce by 30.19%.The present invention can be significantly
Degree reduces the cholesterol level in laying hen blood, so as to reach the purpose for reducing cholesterol.
Influence of the Chinese herb feed additive of table 3 to Laying-hen Serum biochemical indicator
Unit：mg/dl
（3）The influence of Medical Herb Supplement in Layer Dietary on Cholesterol Content of Egg
After off-test, every group each repeats to choose 3 pieces of eggs, using high ferro-sulfuric acid determination of color Egg cholesterol amount
Measure, as a result as shown in table 3, Chinese herb feed additive can significantly reduce yolk weight cholesterol level and cholesterol content in eggs.
Cholesterol in egg is all present in yolk, and the present invention can produce low-cholesterol egg.
The influence of the Medical Herb Supplement in Layer Dietary on Cholesterol Content of Egg of table 4
To sum up above test result analysis, the present invention go out Chinese herbal feed additive, safely, effectively, green, environmental protection, can have
Effect reduces in laying hen blood and the cholesterol level of egg, improves the production performance of laying hen, is beneficial to food security and the people
The general level of the health.
Claims (4)
1. a kind of Chinese herb feed additive for reducing cholesterol content in eggs, it is characterised in that be made up of following Chinese medicine：Certainly
Pine torch, lotus leaf, hawthorn, the red sage root, honeysuckle, Ilex Latifolia Thunb, ginkgo biloba p.e, oriental wormwood.
2. Chinese herb feed additive according to claim 1, it is characterised in that the weight ratio of the medicine is：Cassia seed 20-
40 parts, lotus leaf 30-50 parts, hawthorn 30-50 parts, red sage root 10-30 parts, honeysuckle 5-20 parts, Ilex Latifolia Thunb 5-20 parts, ginkgo leaf extraction
Thing 5-20 parts, oriental wormwood 10-30 parts.
3. Chinese herb feed additive according to claim 1, it is characterised in that the weight ratio of the medicine is：Cassia seed 30
Part, 40 parts of lotus leaf, 40 parts of hawthorn, 20 parts of the red sage root, 10 parts of honeysuckle, 10 parts of Ilex Latifolia Thunb, 10 parts of ginkgo biloba p.e, oriental wormwood 20
Part.
A kind of 4. application side of Chinese herb feed additive for reducing cholesterol content in eggs in Egg cholesterol amount is reduced
Method, it is characterised in that addition weight ratio of the Chinese herb feed additive in egg feedstuff is 1%-3%.
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Cited By (2)
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| CN109601759A (en) * | 2019-02-14 | 2019-04-12 | 江西赣达牧业有限公司 | A kind of egg duck feed containing plant extracts |
| CN110973360A (en) * | 2019-11-27 | 2020-04-10 | 江苏三仪动物营养科技有限公司 | Livestock and poultry feed additive and preparation method thereof |
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| CN109601759A (en) * | 2019-02-14 | 2019-04-12 | 江西赣达牧业有限公司 | A kind of egg duck feed containing plant extracts |
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