CN107728338A - Ortho-K - Google Patents
Ortho-K Download PDFInfo
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- CN107728338A CN107728338A CN201711276716.4A CN201711276716A CN107728338A CN 107728338 A CN107728338 A CN 107728338A CN 201711276716 A CN201711276716 A CN 201711276716A CN 107728338 A CN107728338 A CN 107728338A
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- 210000004087 cornea Anatomy 0.000 claims abstract description 52
- 230000007704 transition Effects 0.000 claims description 27
- 230000002829 reductive effect Effects 0.000 claims description 4
- 210000001508 eye Anatomy 0.000 description 18
- 238000012937 correction Methods 0.000 description 16
- 230000004438 eyesight Effects 0.000 description 15
- 201000010041 presbyopia Diseases 0.000 description 12
- 208000001491 myopia Diseases 0.000 description 8
- 208000014733 refractive error Diseases 0.000 description 8
- 230000008859 change Effects 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 230000001788 irregular Effects 0.000 description 6
- 238000000465 moulding Methods 0.000 description 6
- 208000029091 Refraction disease Diseases 0.000 description 5
- 230000004430 ametropia Effects 0.000 description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 5
- 238000013461 design Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 230000004379 myopia Effects 0.000 description 5
- 230000003287 optical effect Effects 0.000 description 5
- 229910052760 oxygen Inorganic materials 0.000 description 5
- 239000001301 oxygen Substances 0.000 description 5
- 239000011521 glass Substances 0.000 description 4
- 208000002177 Cataract Diseases 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- 206010047513 Vision blurred Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000001747 pupil Anatomy 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000002153 concerted effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003560 epithelium corneal Anatomy 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000979 retarding effect Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/041—Contact lenses for the eyes bifocal; multifocal
- G02C7/045—Sectorial configuration
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures
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- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Eyeglasses (AREA)
- Prostheses (AREA)
Abstract
The present invention relates to Ortho-K, inner surface towards eye cornea and the outer surface relative with the inner surface when Ortho-K is included in wearing, the inner surface is included positioned at the base curve area at center, wherein, the base curve area is used to oppress anterior surface of cornea and fashion into anterior surface of cornea have the shape consistent with the base curve area, wherein, the base curve area includes two or more regions, and at least two in described two or more regions have different radius of curvature.
Description
Technical field
The present invention relates to Ortho-K, and relating more specifically to base curve area has the cornea of more than one radius of curvature moulding
Mirror.
Background technology
Presbyopia is that people step into after person in middle and old age the visual problem necessarily occurred.With age, eye regulating power is gradual
Decline so as to cause patient regarding nearly difficulty so that near work, it is necessary to separately add convex lens outside the correction of its static refraction
Can just there is clearly near vision, this phenomenon is referred to as presbyopia.With the modern improvement of people's living standards, especially like to be beautiful women
To the middle age, they increasingly improve in the requirement to image, it is desirable to oneself keep young state at any time, it is undesirable to stick one's chin out old
Colored state, puzzlement caused by presbyopic problem are increasingly severe.Current presbyopia mainly by wearing reading glasses, operation, pendant outside
The modes such as multifocal contact lenses are worn to solve.Outer contact lenses worn presbyopic glasses or worn in the daytime etc. are outer wear mode in convenience, rectify
Problem be present in terms of plus effect, correction stability, it is especially outer to wear presbyopic glasses, have a strong impact on wearer's image.Operation refers mainly to
Cornea implant, or all kinds of multifocal intraocular lenses of implantation, this kind of correction mode are all irreversible, and human ocular tissues are produced
Raw damage, the problem of different degrees of in terms of security being present, and the people of this age bracket has generally arrived the cataract high-incidence season,
Other eye treatments, such as cataract operation etc. are subsequently faced, the mode of operation brings serious puzzlement to subsequent procedures.Therefore
It is badly in need of a kind of hidden, effective, safe presbyopia corrective measure.
Cornea is moulding to use rigid air-permeable type contact lens（Abbreviation Ortho-K）It is that one kind uses high oxygen flow hardness material
Material is made, by temporarily changing corneal surface shape, to reach the product for temporarily sexually revising ametropic purpose.This is a kind of reversible
Property, Non-surgical correction of refractive errors product, the pattern that usually night wears（Mirror sleep is worn at night, plucks mirror daytime）, wearer's wearing
The ametropia problem " being cured " of oneself is thought afterwards, and is not constrained on daytime by any external condition, is rectified with other eyesights
Positive means are compared, and will not be brought any additional puzzlement, are a kind of very outstanding vision correction means.
Ortho-K dioptric, which rescues principle and common contact lens, the difference of essence, and it wears at night, optics
Optical effect is not played in area in itself, but by the wearing of certain time, anterior surface of cornea is modelled as Ortho-K optics
Surface behind area（Also known as base curve area）Shape, the refractive power of cornea itself is changed, realize the effect that dioptric is rescued.If
The flat paraxial curvature radius of ratio cornea itself that the base curve area of Ortho-K is done is more flat, then plays the work of myoporthosis
With；If the flat paraxial curvature radius of ratio cornea itself that Ortho-K base curve area is done is more precipitous, distance vision correction is played
Effect.
In several stages of the development experience of Ortho-K, it is divided into a variety of designs such as three arc areas, four arc areas, multi sphere area,
The design in whichever stage, the design of its base curve area is all consistent, is one section of complete circular arc, other several common structures of segmental arc
Into geometry designs, auxiliary base curve reaches the compressing of corneal and moulding, makes to produce between eyeglass inner surface, tear, corneal epithelium
Fluidics power, eyeglass mechanical pressure and eyelid activity caused by corneal middle section of making a concerted effort impose strength.Fig. 1 shows
Go out the schematic diagram of Ortho-K, wherein, BC is base curve area, and RC is reversion arc area, and AC is to match somebody with somebody Shi Hu areas, and PC is optional side
Arc area.Ortho-K can also not have Bian Hu areas, such as the Ortho-K of some three arc areas design, and it matches somebody with somebody suitable arc and side
Arc is integral straight line arc.
Base curve area is the main treatment region of Ortho-K, and traditional Ortho-K base curve area is each designed to a ball
Face, its radius of curvature are designed according to the requirement of the decreasing concentration of patient.Existing Ortho-K is most to be directed to near-sightedness correction
It is designed.Find that some patientss can produce near-sighted type periphery defocus after wearing Ortho-K during Clinical practice,
Axis oculi is controlled to increase, thus Ortho-K is used for adolescent myopia more and rescued and prevention and control, is then disclosed in WO2004/015479
A kind of Ortho-K of the more precipitous correction long sight of base curve area axle more flat than cornea.
Long sight and presbyopia have that essence is different, and long sight is a kind of ametropia, and presbyopia is a kind of adjusting force forfeiture.Presbyopia
Patient, which needs to realize simultaneously in the case of ensureing distant vision clearly, regards near function.Currently without any Ortho-K
Correcting action can be played to presbyopia.
The content of the invention
The invention provides a kind of Ortho-K, towards in eye cornea when the Ortho-K is included in wearing
Surface and the outer surface relative with the inner surface, the inner surface are included positioned at the base curve area at center, wherein, the base curve
Area is used to oppress anterior surface of cornea and fashion into anterior surface of cornea have the shape consistent with the base curve area, wherein, it is described
Base curve area includes two or more regions, and at least two in described two or more regions have different curvature half
Footpath.
In one embodiment, two or more regions in the base curve area are included positioned at the circular center at center
Domain and one or more concentric circle ring areas around the central area.
In one embodiment, the radius of curvature in two or more regions in the base curve area, which is radially presented, alternately becomes
Change.
In one embodiment, the radius of curvature in two or more regions in the base curve area outwards gradually subtracts from center
It is small.
In one embodiment, the diameter of the central area is more than 1mm, preferably more than 2mm.
In one embodiment, two or more regions in the base curve area are two or more sector regions, and
And described two or more sector regions collectively constitute the base curve area.
In one embodiment, two or more regions in the base curve area are two or more sector regions, institute
Stating base curve area also includes smooth transition region between the adjacent sector region of each two, and wherein, it is described two or
More sector regions and the smooth transition region collectively constitute the base curve area.
In one embodiment, two or more regions in the base curve area are in irregular shape.
In one embodiment, two or more regions in the base curve area are positioned at middle first area and position
Second area and the 3rd region in the first area both sides, and the first area, the second area and described
Three regions collectively constitute the base curve area.
In one embodiment, two or more regions in the base curve area are positioned at middle first area and position
Second area and the 3rd region in the first area both sides, the base curve area are also included positioned at the first area and described
The first smooth transition region between second area and second between the first area and the 3rd region flat
Sliding transitional region, and wherein, the first area, the second area, the 3rd region, first smooth transition region
Domain and second smooth transition region collectively constitute the base curve area.
In one embodiment, two or more regions in the base curve area are first area and second area, described
First area is a part for annulus, and the center of the second area has complete circular portion, and wherein, described first
Region and the second area collectively constitute the base curve area.
In one embodiment, two or more regions in the base curve area are first area and second area, described
First area is a part for annulus, and the center of the second area has complete circular portion, and the base curve area also includes
Smooth transition region between the first area and the second area, and wherein, the first area, described
Two regions and the smooth transition region collectively constitute the base curve area.
In one embodiment, the T being calculated by following formula is+0.5D to+5.0D, is preferably+0.75D to+3.5D,
More preferably+1.0D to+3.0D：
Wherein, R1For the maximum curvature radius in the base curve area, unit mm, R2For the minimum profile curvature radius in the base curve area,
Unit is mm, and n is the refractive index of cornea, value 1.3375.
In one embodiment, the maximum curvature radius in the base curve area is 6.0mm to 10.5mm, and preferably 7.0mm is extremely
10.0mm。
In one embodiment, the minimum profile curvature radius in the base curve area is 5.51mm to 10.34mm, preferably 5.65mm
To 9.85mm, more preferably 6.53mm to 9.71mm.
In one embodiment, a diameter of 4.5mm to 7.0mm in the base curve area, preferably 5.0mm to 6.8mm, it is more excellent
5.2mm is elected as to 6.5mm.
In one embodiment, the base curve area is circular.
In one embodiment, the base curve area is oval.
The present invention at least has the following advantages that.
（1）The base curve area of the Ortho-K of the present invention has more than one radius of curvature, can make cornea after moulding
More than one focus is formed, using mirror is worn at night, plucks the wearing mode of mirror daytime, realizes and ametropia is rectified with merging for presbyopia
Just, it is convenient, attractive in appearance, effective, more meet pursuit of the modern to quality of the life.
（2）The correction mode eyeglass such as frame-generic presbyopic glasses, common multifocal contact lenses can not keep synchronous with eyeball, suffer from
Person needs according to lens position after wearing and sees that the position of thing is constantly adjusted, or occurs when eyeglass occurs not placed in the middle
The states such as dazzle, blurred vision, dizziness；Ortho-K is naturally in center condition when wearing, and no matter user is seen to which
Orientation, all without occur because of lens position change and caused by blurred vision with it is inapplicable.
（3）Presbyopia patient age is larger, and majority enters the cataract high-incidence season.The activity based on keratocyte of the present invention,
Reversible correction, after a period of time is disabled, cornea can return to original state, without any infringement, facilitate patient it is follow-up its
Its eye treatment, it is safer for modus operandi.
Term defines
Unless special circumstances, the term that otherwise following definition uses suitable for this specification.
Base curve area（BC）It is most central positioned at Ortho-K, it is the inner surface in optics area, for oppressing anterior surface of cornea simultaneously
Anterior surface of cornea is modelled as its shape, it is moulding after the cornea region be optics area, play a part of optical imagery.
Invert arc area（RC）It is the Two Areas closely coupled with base curve area, plays connection base curve area and with Shi Hu areas
Effect, forms gap between Ortho-K and anterior surface of cornea, plays a part of storing tear and promotes tear to circulate.
With Shi Hu areas（AC）Positioning arc area, match arc area etc. are called, close to reversion arc area, the region and cornea shape
Match somebody with somebody, play a part of positioning.
Bian Hu areas（PC）It is optional, positioned at Ortho-K outer most edge, with closely coupled with Shi Hu areas, general ratio is with suitable
Arc area is more flat, with anterior corneal surface present it is certain turn over rake angle degree, ensure cornea and moulding mirror periphery tear, oxygen exchange and
Circulation.
Depending on closely referring to seeing nearby, refer generally to see apart from eyes about at 30cm, corresponding eyesight is near vision.
Refer to seeing at a distance depending on remote, refer generally to see that apart from eyes about 5m corresponding eyesight is distant vision at a distance.
Refer to seeing depending in it is remote, near between, refer generally to see beyond eyes about 30cm, the distance within 5m, it is corresponding
Eyesight is intermediate range eyesight.
In addition, unless otherwise defined, otherwise the implication of all scientific and technical terminologies used herein with it is of the art
It is consistent that technical staff, which is generally understood that,.If any inconsistent, by this specification and its including definition be defined.
Brief description of the drawings
Fig. 1 schematically shows the side cross-sectional view of Ortho-K.
Fig. 2 schematically shows the base curve area of the Ortho-K according to the present invention.
Fig. 3 A schematically show the base curve area of the Ortho-K of a specific embodiment according to the present invention.
Fig. 3 B schematically show the base curve area of the Ortho-K of a specific embodiment according to the present invention.
Fig. 4 A schematically show the base curve area of the Ortho-K of a specific embodiment according to the present invention.
Fig. 4 B schematically show the base curve area of the Ortho-K of a specific embodiment according to the present invention.
Fig. 5 A schematically show the base curve area of the Ortho-K of a specific embodiment according to the present invention.
Fig. 5 B schematically show the base curve area of the Ortho-K of a specific embodiment according to the present invention.
Fig. 5 C schematically show the base curve area of the Ortho-K of a specific embodiment according to the present invention.
Fig. 5 D schematically show the base curve area of the Ortho-K of a specific embodiment according to the present invention.
Embodiment
Specific examples below is only intended to the present invention be further explained explanation, but the present invention does not limit to
In following specific embodiment.Any change on the basis of these embodiments, as long as meeting the spirit of the present invention
And scope, fall within protection scope of the present invention.
The refractive status of cornea is mainly determined by its radius of curvature.In practical clinical, the radius of curvature of cornea with
The conversion relation commonly used between corneal diopter：
（1）
Wherein, K is the diopter of cornea, and unit D, R are the radius of curvature of anterior surface of cornea, and unit mm, n are the folding of cornea
Penetrate rate.For example, n can be 1.3375.
As shown in figure 1, when Ortho-K is included in wearing towards eye cornea inner surface IS and with inner surface phase
To outer surface OS.The inner surface IS of Ortho-K includes the base curve area BC positioned at center, positioned at base curve area BC radial outsides
Annular reversion arc area RC and match somebody with somebody Shi Hu areas AC positioned at the annular of reversion arc area RC radial outsides.In some implementations
In example, the inner surface IS of Ortho-K can also include the Bian Hu areas PC for being located at the annular with Shi Hu areas AC radial outsides.
When wearing, the base curve area BC of Ortho-K contacts with the preceding surface of eye cornea.When patient occurs ametropia, pass through
The base curve area BC of Ortho-K adjusts the radius of curvature on the preceding surface of eye cornea, that is, adjusts the R in above formula, so as to reality
The ametropic correction of existing human eye.In Fig. 2, Fig. 3 A-3B, Fig. 4 A-4B and Fig. 5 A-5D below, shown base curve area BC is round
Shape.However, in certain embodiments, base curve area BC can also have other shapes, such as oval, avette etc..
The present invention creatively proposes that the base curve area of Ortho-K has at least two different radius of curvature so that people
Eye produces at least two focuses after Ortho-K is worn, in optical zones of cornea, so that the ametropia and presbyopia of patient
Corrected simultaneously.
In the Ortho-K according to the present invention, base curve area includes two or more regions.Two of base curve area or
At least two in more regions have different radius of curvature.The face shape in two or more regions in base curve area can be equal
For sphere, the face shape for being either aspherical or a part of region is sphere and the face shape in remaining region is aspherical.Fig. 2
Show that base curve area includes four regions A, B, C and D.As needed, four regions A, B, C and D can have any shape.Four
At least two in region A, B, C and D have different radius of curvature.
In certain embodiments, two or more regions in base curve area 100 are included positioned at the circular center at center
Domain 1001And around the central area 1001One or more concentric circle ring areas 1002、1003、1004…。
In certain embodiments, two or more regions 100 in base curve area 1001、1002、1003、1004... curvature
Radius, which is radially presented, alternately to be changed.Especially, in certain embodiments, base curve area 100 has radially to present and alternately changed
Two kinds of different radius of curvature, wherein, the region 100 in base curve area 1002m-1With first curvature radius, and base curve area 100
Region 1002mWith the second curvature radius different from first curvature radius, wherein, m is greater than the integer equal to 1.Especially
Ground, in certain embodiments, base curve area 100 have three kinds of different radius of curvature that alternately change is radially presented, wherein, base
The region 100 in arc area 1003m-2With first curvature radius, the region 100 in base curve area 1003m-1With different from first curvature half
The second curvature radius in footpath, also, the region 100 in base curve area 1003mWith different from first curvature radius and second curvature radius
The 3rd radius of curvature, wherein, m is greater than the integer equal to 1.Certainly, in further embodiments, base curve area 100 can be with class
As have radially present alternately change other quantity different radius of curvature.
For example, in one embodiment, Ortho-K 10 is made up of high oxygen flow hard material.Ortho-K 10 it is interior
Surface includes base curve area 100, reversion arc area 200, with Shi Hu areas 300 and Bian Hu areas 400.The overall diameter of Ortho-K 10 is
10.4mm, wherein, a diameter of 6.0mm in base curve area 100, the interior diameter in reversion arc area 200 is 6.0mm, overall diameter 7.8mm.
Interior diameter with Shi Hu areas 300 is 7.8mm, overall diameter 9.4mm.The interior diameter in Bian Hu areas 400 is 9.4mm, and overall diameter is
10.4mm.The center thickness of Ortho-K 10 is 0.22mm.
In this embodiment, as shown in Figure 3A, base curve area 100 includes central area 1001And around central area 1001
Three concentric circle ring areas 1002、1003With 1004.Central area 1001A diameter of 3mm.Circle ring area 1002It is interior straight
Footpath is 3mm, overall diameter 4mm.Circle ring area 1003Interior diameter be 4mm, overall diameter 5mm.Circle ring area 1003Interior diameter
For 5mm, overall diameter 6mm.Region 1001、1002、1003With 1004Radius of curvature present alternately change, wherein, central area
1001With circle ring area 1003Radius of curvature it is identical, such as can be 8.88mm, and circle ring area 1002With 1004Curvature
Radius is identical, such as can be 8.54mm.
By wearing the Ortho-K 10, patient plucks cornea after mirror while provides remote, nearly two focuses.Cornea with
Central area 1001With circle ring area 1003The refractive power in corresponding two regions is 38.0D, the correction of realization -5.0D myopia, from
And realize clearly distant vision.Cornea with circle ring area 1002With 1004The refractive power in corresponding two regions is 39.5D,
+ 1.5D additional optical focal power is addition of on the basis of distant vision, so as to realize the function of presbyopia correction.
In the embodiment as shown in fig. 3 a, base curve area includes three concentric circle ring areas.In addition, base curve area can also wrap
Include the concentric annular regions of other quantity.In the embodiment as shown in fig. 3 a, the regional in base curve area is different using two kinds
Radius of curvature replaces, there is provided two focuses.In addition, the regional in base curve area can also use more than two kinds different curvature half
Footpath replaces, so as to produce more than two focus.The diameter of central area and the width of circle ring area（Namely overall diameter with it is interior straight
The half of the difference in footpath）It can be adjusted according to the pupil size of patient, requirement to being clear degree etc..
In certain embodiments, two or more regions 100 in base curve area 1001、1002、1003... radius of curvature from
Center is outwards gradually reduced.
For example, in one embodiment, Ortho-K 10 is made up of high oxygen flow hard material, including it is base curve area 100, anti-
Zhuan Hu areas 200, with Shi Hu areas 300 and Bian Hu areas 400.The overall diameter of Ortho-K 10 is 10.9mm, wherein, base curve area 100
A diameter of 6.5mm, the interior diameter in reversion arc area 200 is 6.5mm, overall diameter 8.3mm.Interior diameter with Shi Hu areas 300 is
8.3mm, overall diameter 9.9mm.The interior diameter in Bian Hu areas 400 is 9.9mm, overall diameter 10.9mm.In Ortho-K 10
Heart thickness is 0.22mm.
In this embodiment, as shown in Figure 3 B, base curve area 100 includes central area 1001And around central area 1001
Four concentric circle ring areas 1002、1003、1004With 1005.Central area 1001A diameter of 4mm.Circle ring area 1002's
Interior diameter is 4mm, overall diameter 4.5mm.Circle ring area 1003Interior diameter be 4.5mm, overall diameter 5mm.Circle ring area 1004
Interior diameter be 5mm, overall diameter 5.5mm.Circle ring area 1005Interior diameter be 5.5mm, overall diameter 6.5mm.Region
1001、1002、1003、1004With 1005Radius of curvature be outwards gradually reduced from center.For example, central area 1001Curvature half
Footpath can be 7.85mm, circle ring area 1002Radius of curvature can be 7.76mm, circle ring area 1003Radius of curvature can be
7.67mm, circle ring area 1004Radius of curvature can be 7.58mm, circle ring area 1005Radius of curvature can be 7.50mm.
The Ortho-K 10 cornea of wearer can be shaped as being followed successively by from center to edge refractive power 43.0D,
43.5D, 44.0D, 44.5D, 45.0D, realize the diopter gradually changed, realization+0.5D to+2.0D gradual changes additional light focus
Degree.
In the embodiment shown in figure 3b, base curve area includes central area and four concentric circle ring areas, radius of curvature
Outwards it is gradually reduced from center, so as to provide five kinds of different diopters.In addition, base curve area can also include the same of other quantity
Heart circle ring area, so as to provide the different diopters of other quantity.The diameter of central area and the width of circle ring area（
That is the half of the difference of overall diameter and interior diameter）It can be adjusted according to the pupil size of patient, requirement to being clear degree etc.
It is whole.
The periphery defocus of myopiaization refers to that refractive power of opthalmic optics' system on periphery is larger, and the focus point of formation, which is fallen within, to be regarded
Before nethike embrane, clinical evidence shows that the periphery defocus of myopiaization can be used for the control of adolescent myopia.Technical scheme
Caused technique effect also includes：Teenager wears the Ortho-K described in the technical scheme, can form myopiaization defocus,
Prevent axis oculi from increasing, retarding myopia is deepened.
In some embodiments of the invention, central area 1001Diameter be more than 1mm, preferably more than 2mm.
In other embodiments of the present invention, two or more regions in base curve area are two or more fan sections
Domain, two or more sector regions collectively constitute base curve area.In other embodiments of the present invention, two of base curve area or
More regions are two or more sector regions, and base curve area also includes flat between the adjacent sector region of each two
Sliding transitional region, and two or more sector regions and smooth transition region collectively constitute base curve area.
For example, in one embodiment, Ortho-K is made up of high oxygen flow hard material, including it is base curve area 100', anti-
Zhuan Hu areas 200', with Shi Hu areas 300' and Bian Hu areas 400'.Ortho-K 10' overall diameter is 10.6mm, wherein, base curve area
100' a diameter of 6.2mm, reversion arc area 200' interior diameter is 6.2mm, overall diameter 8.0mm.With in Shi Hu areas 300'
A diameter of 8.0mm, overall diameter 9.6mm.Bian Hu areas 400' interior diameter is 9.6mm, overall diameter 10.6mm.Ortho-K
Center thickness be 0.16mm.
In one embodiment, as shown in Figure 4 A, the base curve area 100' of Ortho-K two or more regions are
Sector region 100'1And 100'2, and sector region 100'1And 100'2Collectively constitute base curve area 100'.In this embodiment,
Sector region 100'1Central angle be 240 °, and sector region 100'2Central angle be 120 °.
In one embodiment, as shown in Figure 4 B, the base curve area 100' of Ortho-K two or more regions are
Sector region 100'1And 100'2.Base curve area 100' also includes being located at sector region 100'1And 100'2Between smooth transition region
Domain 100'3And 100'4, and sector region 100'1And 100'2And smooth transition region 100'3And 100'4Collectively constitute base curve
Area 100'.In this embodiment, sector region 100'1Central angle be 220 °, and sector region 100'2Central angle be
100°.Sector region 100'1Radius of curvature be 9.0mm, and sector region 100'2Radius of curvature be 9.78mm.It is smoothed
Cross region 100'3And 100'4Central angle be 20 °.
By wearing the Ortho-K, after cornea is shaped, the refractive power of far region is regarded as 37.5D, near reading range domain
Refractive power is 34.5D, the base curve area 100' of Ortho-K sector region 100'1And 100'2It can provide+3.0D's for cornea
Additional optical focal power, make wearer and meanwhile reach regarding far with regarding nearly bifocus, the luminous energy accounting of two focuses is 2.2:1.Due to two
Individual sector region is connected by smooth transition region, therefore vestige of the cornea without obvious subregion after patient's wearing.
In the embodiment shown in Fig. 4 A, 4B, base curve area includes two sector regions.In addition, base curve area can also include
More than two sector region, so as to produce more than two focus.Sector region and the central angle of smooth transition region can bases
Need to be adjusted.
In other embodiments of the present invention, two or more regions in base curve area can be in irregular shape.
For example, in one embodiment, as shown in Figure 5A, base curve area 100'' two or more regions are in being located at
Between first area 100''1And positioned at the first area 100''1The second area 100'' of both sides2With the 3rd region
100''3, and first area 100''1, second area 100''2With the 3rd region 100''3Collectively constitute base curve area 100''.
In another embodiment, as shown in Figure 5 B, base curve area 100'' two or more regions are positioned at middle first area
100''1And positioned at the first area 100''1The second area 100'' of both sides2With the 3rd region 100''3, base curve area
100'' can also include being located at first area 100''1With second area 100''2Between the first smooth transition region 100''4
And positioned at first area 100''1With the 3rd region 100''3Between the second smooth transition region 100''5, and the firstth area
Domain 100''1, second area 100''2, the 3rd region 100''3, the first smooth transition region 100''4With the second smooth transition region
Domain 100''5Collectively constitute base curve area 100''.
In the embodiment shown in Fig. 5 A, 5B, first area 100''1Radius of curvature be 7.30mm, second area
100''2Radius of curvature be 7.00mm, the 3rd region 100''3Radius of curvature be 7.63mm.After cornea is shaped, the firstth area
Domain 100''1Produce 46.2D refractive power, second area 100''2Produce 48.2D refractive powers, the 3rd region 100''3Produce
44.2D refractive power, it can be realized for human eye in being regarded depending on remote ,+2.0D ,+4.0D regards near whole eyesight.
In the embodiment shown in Fig. 5 A, 5B, two or more regions in base curve area are three areas in irregular shape
Domain.In addition, two or more regions in base curve area can also be the region in irregular shape of other quantity, so as to produce other
The focus of quantity.
For example, in one embodiment, as shown in Figure 5 C, base curve area 100''' two or more regions are the firstth areas
Domain 100'''1With second area 100'''2, first area 100'''1It is a part for annulus, second area 100'''2Center
With complete circular portion, and first area 100'''1With second area 100'''2Collectively constitute base curve area 100'''.
In the embodiment, first area 100'''1Radius of curvature be 7.50mm, second area 100'''2Radius of curvature be
7.85mm.After cornea is shaped, first area 100'''1Produce 45.0D refractive power, second area 100'''2Produce 43.0D
Refractive power, can be that human eye realizes that regarding remote ,+2.0D regard near eyesight.First area 100'''1Central angle be 200 °, second
Region 100'''2Central angle be 160 °, second area 100'''2Center there is complete circular portion, its is a diameter of
2.0mm.In another embodiment, as shown in Figure 5 D, base curve area 100''' two or more regions are first areas
100'''1With second area 100'''2, first area 100'''1It is a part for annulus, second area 100'''2Center tool
There is complete circular portion, base curve area 100''' also includes being located at first area 100'''1With second area 100'''2Between
Smooth transition region 100'''3, and first area 100'''1, second area 100'''2With smooth transition region 100'''3Altogether
With composition base curve area 100'''.In this embodiment, first area 100'''1Radius of curvature be 8.44mm, second area
100'''2Radius of curvature be 7.85mm, the 3rd region 100'''3For smooth transition portion, width 0.1mm, its radius of curvature
Between first area and the radius of curvature of second area.After cornea is shaped, first area 100'''1Produce 40.0D's
Refractive power, second area 100'''243.0D refractive powers are produced, can be that human eye realizes that regarding remote ,+3.0D regards near eyesight.Firstth area
Domain 100'''1Central angle be 220 °, second area 100'''2Central angle be 120 °, second area 100'''2Center has
Complete circular portion, its a diameter of 1.8mm.
In the embodiment shown in Fig. 5 C, 5D, two or more regions in base curve area are two areas in irregular shape
Domain.In addition, two or more regions in base curve area can also be the region in irregular shape of other quantity, so as to produce other
The focus of quantity.
The maximum curvature radius in base curve area is determined according to equation below：
（2）
Convolution（1）Obtain：
（3）
Wherein, n is the refractive index of cornea, and R is the original curvature radius on the preceding surface of users cornea, and unit mm, K are dioptric
Not positive correct amount, unit D, R1For the maximum curvature radius in base curve area, unit mm.Rafractive, inserted sheet can be used
The modes such as optometry measure the original curvature radius R and correction of refractive errors amount K of the anterior surface of cornea of wearer.
The minimum profile curvature radius in base curve area is determined according to equation below：
（4）
I.e.：
（5）
Wherein, n be cornea refractive index, R1For the maximum curvature radius in base curve area, unit mm, T are needed for wearer
Presbyopic correct amount, unit D, R2For the minimum profile curvature radius in base curve area, unit mm.
Presbyopic correct amount T according to needed for the presbyopic degree of wearer determines wearer.If wearer is in distant vision
On the basis of correct correction, see that the nearly minimum distance that can reach is M, unit mm, then the presbyopic correct amount needed for wearer
For：
（6）
Normally the presbyopic correct amount T of human eye is+0.5D to+5.0D.
In certain embodiments, the diopter K of eye cornea is 38.0D to 47.0D, correction of refractive errors amount K for-
6.0D to 1.0D, then can be according to formula（2）The maximum curvature radius R in base curve area is calculated1For 6.0mm to 10.5mm.With reference to upper
Scope is stated, according to formula（5）The minimum profile curvature radius R in base curve area can be calculated2.Table 1 shows some realities according to the present invention
The data of example are applied, wherein, the refractive index n of cornea is 1.3375.
The maximum curvature radius R in the base curve area of table 11And its corresponding minimum curvature half under different presbyopic correct amount T
Footpath R2
In some embodiments of the invention, Ortho-K be human eye realize presbyopic correct amount T for+0.5D to+
5.0D, it is preferably+0.75D to+3.5D, more preferably+1.0D to+3.0D.
In some embodiments of the invention, the maximum curvature radius in base curve area is 6.0mm to 10.5mm, is preferably
7.0mm to 10.0mm.
In some embodiments of the invention, the minimum profile curvature radius in base curve area is 5.51mm to 10.34mm, is preferably
5.65mm to 9.85mm, more preferably 6.53mm are to 9.71mm.
In some embodiments of the invention, a diameter of 4.5mm to 7.0mm in base curve area, preferably 5.0mm to 6.8mm,
More preferably 5.2mm to 6.5mm.
Although reference（It is one or more）Exemplary embodiment describes the present invention, but those skilled in the art will
Understand, wanted the invention is not restricted to precise structure described herein and part, and without departing from such as appended right
In the case of the spirit and scope of the invention for asking restriction, various modifications, change and deformation are understood that from description above.The present invention
Do not limited by the shown sequence of step, because some steps can be entered in a different order and/or with other steps simultaneously
OK.Therefore, the invention is not restricted to disclosed（It is one or more）Specific embodiment, but will include falling wanting in appended right
All embodiments in the range of asking.
Claims (18)
1. a kind of Ortho-K, when the Ortho-K is included in wearing towards eye cornea inner surface and with it is described
The relative outer surface of inner surface, the inner surface are included positioned at the base curve area at center, wherein, the base curve area is used to oppress cornea
Anterior surface of cornea is simultaneously fashioned into and has the shape consistent with the base curve area by preceding surface, wherein, the base curve area includes two
Or more region, at least two in described two an or more region have different radius of curvature.
2. Ortho-K according to claim 1, wherein, two or more regions in the base curve area include being located at
The circular central area at center and one or more concentric circle ring areas around the central area.
3. Ortho-K according to claim 2, wherein, the curvature half in two or more regions in the base curve area
Footpath, which is radially presented, alternately to be changed.
4. Ortho-K according to claim 2, wherein, the curvature half in two or more regions in the base curve area
Footpath is outwards gradually reduced from center.
5. Ortho-K according to claim 2, wherein, the diameter of the central area is more than 1mm, preferably more than
2mm。
6. Ortho-K according to claim 1, wherein, two or more regions in the base curve area be two or
More sector regions, and described two or more sector regions collectively constitute the base curve area.
7. Ortho-K according to claim 1, wherein, two or more regions in the base curve area be two or
More sector regions, the base curve area also include the smooth transition region between the adjacent sector region of each two, and
And wherein, described two or more sector regions and the smooth transition region collectively constitute the base curve area.
8. Ortho-K according to claim 1, wherein, two or more regions in the base curve area be shape not
Rule.
9. Ortho-K according to claim 8, wherein, two or more regions in the base curve area are in being located at
Between first area and the second area positioned at the first area both sides and the 3rd region, and the first area, institute
State second area and the 3rd region collectively constitutes the base curve area.
10. Ortho-K according to claim 8, wherein, two or more regions in the base curve area are to be located at
Middle first area and the second area positioned at the first area both sides and the 3rd region, the base curve area also includes position
The first smooth transition region between the first area and the second area and positioned at the first area and described
The second smooth transition region between 3rd region, and wherein, the first area, the second area, the 3rd area
Domain, first smooth transition region and second smooth transition region collectively constitute the base curve area.
11. Ortho-K according to claim 8, wherein, two or more regions in the base curve area are first
Region and second area, the first area are a parts for annulus, and the center of the second area has complete rounded portions
Point, and wherein, the first area and the second area collectively constitute the base curve area.
12. Ortho-K according to claim 8, wherein, two or more regions in the base curve area are first
Region and second area, the first area are a parts for annulus, and the center of the second area has complete rounded portions
Point, the base curve area also includes the smooth transition region between the first area and the second area, and wherein,
The first area, the second area and the smooth transition region collectively constitute the base curve area.
13. Ortho-K according to claim 1, wherein, the T being calculated by following formula is+0.5D to+5.0D,
Preferably+0.75D to+3.5D, more preferably+1.0D to+3.0D：
Wherein, R1For the maximum curvature radius in the base curve area, unit mm, R2It is single for the minimum profile curvature radius in the base curve area
Position be mm, and n is the refractive index of cornea, value 1.3375.
14. Ortho-K according to claim 1, wherein, the maximum curvature radius in the base curve area for 6.0mm extremely
10.5mm, preferably 7.0mm are to 10.0mm.
15. Ortho-K according to claim 1, wherein, the minimum profile curvature radius in the base curve area for 5.51mm extremely
10.34mm, preferably 5.65mm are to 9.85mm, more preferably 6.53mm to 9.71mm.
16. Ortho-K according to claim 1, wherein, a diameter of 4.5mm to 7.0mm in the base curve area, preferably
For 5.0mm to 6.8mm, more preferably 5.2mm to 6.5mm.
17. Ortho-K according to claim 1, wherein, the base curve area is circular.
18. Ortho-K according to claim 1, wherein, the base curve area is oval.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711276716.4A CN107728338B (en) | 2017-12-06 | 2017-12-06 | Cornea shaping mirror |
| JP2020547273A JP7028987B2 (en) | 2017-12-06 | 2018-11-30 | Orthokeratology lens and its manufacturing method |
| PCT/CN2018/118438 WO2019109862A2 (en) | 2017-12-06 | 2018-11-30 | Orthokeratology lens and method for manufacture thereof |
| US16/770,314 US11662606B2 (en) | 2017-12-06 | 2018-11-30 | Orthokeratology lens and method for making orthokeratology lenses |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711276716.4A CN107728338B (en) | 2017-12-06 | 2017-12-06 | Cornea shaping mirror |
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| CN114545659A (en) * | 2022-03-03 | 2022-05-27 | 上海艾康特医疗科技有限公司 | Corneal contact lens and design method thereof |
| CN114967176A (en) * | 2022-06-15 | 2022-08-30 | 潍坊眼科医院有限责任公司 | Method and device for manufacturing orthokeratology lens based on cornea shape and refraction data |
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| CN107728338B (en) | 2024-01-26 |
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