CN107727751A - The detection method and device of whitening spot-removing composition in a kind of cosmetics - Google Patents
The detection method and device of whitening spot-removing composition in a kind of cosmetics Download PDFInfo
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- CN107727751A CN107727751A CN201710931119.4A CN201710931119A CN107727751A CN 107727751 A CN107727751 A CN 107727751A CN 201710931119 A CN201710931119 A CN 201710931119A CN 107727751 A CN107727751 A CN 107727751A
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- cosmetics
- blending tank
- chromatograph
- removing composition
- whitening spot
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses the detection method and device of whitening spot-removing composition in a kind of cosmetics, including blending tank, ultrasonic machine, chromatograph and monitor terminal, blending tank upper end is provided with upper lid, upper lid center is provided with through hole, run through cosmetics ascending pipe in through hole, molecular filtration membrane is provided with the middle part of blending tank inner chamber, buffer salt solution is loaded with blending tank, blending tank is placed in ultrasonic machine, ultrasonic machine inwall is provided with heating plate, and cooling-water temperature sensor is installed in heating plate, mixing pot bottom passes through pipeline communication chromatograph, chromatograph connects monitor terminal, operation principle of the present invention is simple, the accurate detection to whitening spot-removing composition in cosmetics can be realized, detection efficiency is high.
Description
Technical field
The present invention relates to cosmetics detection technique field, the detection method of whitening spot-removing composition in specially a kind of cosmetics
And device.
Background technology
With the development of various skin-whitening Topical therapies, most of cosmetics for skin-whitening have used more than one
Kind whitening spot-removing composition, this is due to that a kind of whitening spot-removing composition only plays inhibitory action to a step of skin darkening, so
Skin darkening is effectively controlled to need to control effectively to links, i.e., " cooperative effect " whitening spot-removing is theoretical.
There will be safety issue, particularly new whitening spot-removing composition for the cross-reference of a variety of whitening spot-removing compositions
The appearance time is disorderly whole, lacks reliable both effectiveness and malicious rational information.It has been suggested that the cross-reference of whitening spot-removing composition and
Normal enzymatic conversion of the tyrosine to melanin in skin will be disturbed by being excessively used, and then cause the adverse reaction of skin.In addition,
Overdose has obvious cytotoxic effect to melanocyte in skin using the new whitening spot-removing composition in part.In market
Bad businessman usually pretends to be high-end whitening spot-removing composition to be added to cosmetics using disabled or low side whitening spot-removing composition
In, therefore, the detection of whitening spot-removing composition is particularly important in cosmetics.Although detection means of the prior art can obtain into
Divide content, but detection efficiency is low, precision is low.
The content of the invention
It is an object of the invention to provide the detection method and device of whitening spot-removing composition in a kind of cosmetics, with solution
State the problem of being proposed in background technology.
To achieve the above object, the present invention provides following technical scheme：The detection of whitening spot-removing composition in a kind of cosmetics
Device, including blending tank, ultrasonic machine, chromatograph and monitor terminal, the blending tank upper end are provided with upper lid, in the upper lid
The heart is provided with through hole, and cosmetics ascending pipe is run through in the through hole, and molecular filtration membrane is provided with the middle part of the blending tank inner chamber, described mixed
Close in tank and be loaded with buffer salt solution, the blending tank is placed in ultrasonic machine, and the ultrasonic machine inwall is provided with heating plate, and institute
State and cooling-water temperature sensor is installed in heating plate, the mixing pot bottom passes through pipeline communication chromatograph, the chromatography
Instrument connects monitor terminal.
Preferably, the material of the molecular filtration membrane includes butyl formate 10-20 parts, sodium metasilicate 5-15 in parts by weight
Part, macromolecule dispersing agent 3-9 parts, polyethylene glycol 2-8 parts, organic antibacterial agent 4-12 parts and hydrophily pore former 10-30 parts.
Preferably, the chromatograph includes operational amplifier A, operational amplifier B and gate circuit and not circuit,
The operational amplifier A electrode input end connects resistance A one end and thermistor A one end, resistance A other ends ground connection respectively；Institute
State operational amplifier A negative input concatenation operation amplifier B negative inputs and connect power end, the operational amplifier B is just
Pole input connects resistance B one end and thermistor B one end, resistance B other ends ground connection, the thermistor B other ends respectively
Power end is connected by rectification circuit with the thermistor A other ends；The operational amplifier A output end and operational amplifier B
Output end connects and gate circuit input, described and gate output connecting triode A base stages, triode A colelctor electrodes respectively
Power end is connected, emitter stage connects heater relay and not circuit one end, not circuit other end connecting triode B respectively
Base stage, the triode B emitter stages connect chromatograph relay and are grounded.
Preferably, it is installed with control valve on the pipeline.
Preferably, its detection method comprises the following steps：
A, cosmetics to be detected are injected in cosmetics ascending pipe, cosmetics to be detected flow out through molecule mistake from injection end
Membrane filtration；
B, the liquid after filtering enters in blending tank；
C, ultrasonic machine is opened afterwards, and thermostatic ultrasonic is carried out to the liquid after filtering；
D, the liquid after ultrasound is analyzed by pipeline inflow chromatograph afterwards；
E, the data transfer after analyzing shows whitening spot-removing composition in cosmetics to be measured to monitor terminal on monitor terminal
Content curve map.
Compared with prior art, the beneficial effects of the invention are as follows：
(1) operation principle of the present invention is simple, can realize the accurate detection to whitening spot-removing composition in cosmetics, detection effect
Rate is high.
(2) the molecular filtration membrane chemical stability that the present invention uses is good, and back washing performance is good, and resilience is good, and filtering accuracy is high,
The accuracy of detection of postorder can be improved.
(3) chromatograph that uses of the present invention can realize thermostatic control, prevent chromatograph temperature too high or mistake
Low influence accuracy of detection, further increases operating efficiency.
Brief description of the drawings
Fig. 1 is overall structure diagram of the present invention；
Fig. 2 is chromatograph schematic diagram of the present invention；
In figure：1st, blending tank；2nd, ultrasonic machine；3rd, chromatograph；4th, monitor terminal；5th, upper lid；6th, cosmetics ascending pipe；
7th, molecular filtration membrane；8th, heating plate；9th, cooling-water temperature sensor；10 and gate circuit；11st, not circuit；12nd, rectification circuit；13rd, add
Hot device relay；14th, chromatograph relay；15th, pipeline；16th, control valve.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.It is based on
Embodiment in the present invention, those of ordinary skill in the art are obtained every other under the premise of creative work is not made
Embodiment, belong to the scope of protection of the invention.
Fig. 1-2 is referred to, the present invention provides a kind of technical scheme：The detection dress of whitening spot-removing composition in a kind of cosmetics
Put, including blending tank 1, ultrasonic machine 2, chromatograph 3 and monitor terminal 4, the upper end of blending tank 1 are provided with upper lid 5, the upper center of lid 5
Provided with through hole, cosmetics ascending pipe 6 is run through in through hole, molecular filtration membrane 7 is provided with the middle part of the inner chamber of blending tank 1, is contained in blending tank 1
There is buffer salt solution, blending tank 1 is placed in ultrasonic machine 2, and the inwall of ultrasonic machine 2 is provided with heating plate 8, and is provided with heating plate 8
Cooling-water temperature sensor 9, the bottom of blending tank 1 connect chromatograph 3 by pipeline 15, control valve are installed with pipeline 15
16；Chromatograph 3 connects monitor terminal 4.
In the present invention, the material of molecular filtration membrane 7 include in parts by weight butyl formate 10-20 parts, sodium metasilicate 5-15 parts,
Macromolecule dispersing agent 3-9 parts, polyethylene glycol 2-8 parts, organic antibacterial agent 4-12 parts and hydrophily pore former 10-30 parts.This hair
The molecular filtration membrane chemical stability of bright use is good, and back washing performance is good, and resilience is good, and filtering accuracy is high, it is possible to increase postorder
Accuracy of detection.
In the present invention, chromatograph 3 includes operational amplifier A 1c, operational amplifier B2c and gate circuit 10 and NOT gate
Circuit 11, the operational amplifier A 1c electrode input ends connect resistance A1a one end and thermistor A1b one end, resistance respectively
The A1a other ends are grounded；The operational amplifier A 1c negative inputs concatenation operation amplifier B2c negative inputs simultaneously connect power supply
End, the operational amplifier B 2c electrode input ends connect resistance B2a one end and thermistor B 2b one end, resistance B 2a respectively
The other end is grounded, and the thermistor B2b other ends and thermistor A the 1b other ends connect power supply by rectification circuit 12
End；The operational amplifier A 1c output ends and operational amplifier B 2c output ends connect respectively with the input of gate circuit 10, it is described
With the output end connecting triode A 1d base stages of gate circuit 10, triode A1d colelctor electrodes connection power end, emitter stage connects respectively to be added
Hot device relay 13 and not circuit 11 one end, the other end connecting triode B 2d base stages of not circuit 11, the triode B
2d emitter stages connection chromatograph relay 14 is simultaneously grounded.Comparator output terminal is controlled by the resistance of two thermistors
The high level of output, only when the output end of two comparators exports high level, triode 1d conductings, while triode 2d
Shut-off, now heater relay closure, chromatograph cut-off, realizes thermostatic control, and do not meet in temperature
It is required that when do not worked due to analyzer cut-off, chromatograph, so the precision of the result of its analysis is high.The present invention adopts
Chromatograph can realize thermostatic control, prevent chromatograph influence accuracy of detection too high or too low for temperature, enter one
Step improves operating efficiency.
The detection method of the present invention comprises the following steps：
A, cosmetics to be detected are injected in cosmetics ascending pipe, cosmetics to be detected flow out through molecule mistake from injection end
Membrane filtration；
B, the liquid after filtering enters in blending tank；
C, ultrasonic machine is opened afterwards, and thermostatic ultrasonic is carried out to the liquid after filtering；
D, the liquid after ultrasound is analyzed by pipeline inflow chromatograph afterwards；
E, the data transfer after analyzing shows whitening spot-removing composition in cosmetics to be measured to monitor terminal on monitor terminal
Content curve map.
Operation principle of the present invention is simple, can realize the accurate detection to whitening spot-removing composition in cosmetics, detection efficiency
It is high.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of changes, modification can be carried out to these embodiments, replace without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (5)
1. the detection means of whitening spot-removing composition in a kind of cosmetics, including blending tank (1), ultrasonic machine (2), chromatograph
And monitor terminal (4) (3), it is characterised in that：Blending tank (1) upper end is provided with upper lid (5), and described upper lid (5) center is provided with
Through hole, the through hole is interior to run through cosmetics ascending pipe (6), and molecular filtration membrane (7), institute are provided with the middle part of blending tank (1) inner chamber
State in blending tank (1) and be loaded with buffer salt solution, the blending tank (1) is placed in ultrasonic machine (2), in the ultrasonic machine (2)
Wall is provided with heating plate (8), and cooling-water temperature sensor (9) is provided with the heating plate (8), and blending tank (1) bottom passes through pipe
Road (15) connection chromatograph (3), chromatograph (3) the connection monitor terminal (4).
2. the detection means of whitening spot-removing composition in a kind of cosmetics according to claim 1, it is characterised in that：Described point
The material of sub- filter membrane (7) includes butyl formate 10-20 parts, sodium metasilicate 5-15 parts, macromolecule dispersing agent 3-9 in parts by weight
Part, polyethylene glycol 2-8 parts, organic antibacterial agent 4-12 parts and hydrophily pore former 10-30 parts.
3. the detection means of whitening spot-removing composition in a kind of cosmetics according to claim 1, it is characterised in that：The color
Composing analyzer (3) includes operational amplifier A (1c), operational amplifier B (2c) and gate circuit (10) and not circuit (11), institute
State operational amplifier A (1c) electrode input end and connect resistance A (1a) one end and thermistor A (1b) one end, resistance A (1a) respectively
The other end is grounded；Operational amplifier A (1c) negative input concatenation operation amplifier B (2c) negative inputs simultaneously connect power supply
End, operational amplifier B (2c) electrode input end connect resistance B (2a) one end and thermistor B (2b) one end, resistance respectively
B (2a) other end is grounded, and thermistor B (2b) other ends and thermistor A (1b) other end passes through rectification circuit
(12) power end is connected；Operational amplifier A (1c) output end and operational amplifier B (2c) output end connect and door electricity respectively
Road (10) input, it is described to be connected with gate circuit (10) output end connecting triode A (1d) base stage, triode A (1d) colelctor electrode
Power end, emitter stage connect heater relay (13) and not circuit (11) one end respectively, and not circuit (11) other end connects
Triode B (2d) base stage is connect, triode B (2d) the emitter stage connection chromatograph relay (14) is simultaneously grounded.
4. the detection means of whitening spot-removing composition in a kind of cosmetics according to claim 1, it is characterised in that：The pipe
Control valve (16) is installed with road (15).
5. realize the detection method of the detection means of whitening spot-removing composition in a kind of cosmetics described in claim 1, its feature
It is：Its detection method comprises the following steps：
A, cosmetics to be detected are injected in cosmetics ascending pipe, cosmetics to be detected flow out through molecular filtration membrane from injection end
Filtering；
B, the liquid after filtering enters in blending tank；
C, ultrasonic machine is opened afterwards, and thermostatic ultrasonic is carried out to the liquid after filtering；
D, the liquid after ultrasound is analyzed by pipeline inflow chromatograph afterwards；
E, the data transfer after analyzing shows the content of whitening spot-removing composition in cosmetics to be measured to monitor terminal on monitor terminal
Curve map.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710931119.4A CN107727751A (en) | 2017-10-09 | 2017-10-09 | The detection method and device of whitening spot-removing composition in a kind of cosmetics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710931119.4A CN107727751A (en) | 2017-10-09 | 2017-10-09 | The detection method and device of whitening spot-removing composition in a kind of cosmetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107727751A true CN107727751A (en) | 2018-02-23 |
Family
ID=61208789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710931119.4A Pending CN107727751A (en) | 2017-10-09 | 2017-10-09 | The detection method and device of whitening spot-removing composition in a kind of cosmetics |
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| Country | Link |
|---|---|
| CN (1) | CN107727751A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109061079A (en) * | 2018-06-12 | 2018-12-21 | 合肥丰洁生物科技有限公司 | A kind of cosmetics experiment detection device |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104569187A (en) * | 2014-12-17 | 2015-04-29 | 深圳出入境检验检疫局食品检验检疫技术中心 | Detection method and device for whitening and freckle-removing components in cosmetics |
| WO2016031616A1 (en) * | 2014-08-25 | 2016-03-03 | 日東電工株式会社 | Sample sampling material for high-performance liquid chromatography |
| CN205643258U (en) * | 2016-03-17 | 2016-10-12 | 广东华鑫检测技术有限公司 | Chromatographic analyzer |
| CN206248622U (en) * | 2016-11-17 | 2017-06-13 | 广州大澳化妆品有限公司 | The testing equipment of IPBC in a kind of cosmetics |
-
2017
- 2017-10-09 CN CN201710931119.4A patent/CN107727751A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016031616A1 (en) * | 2014-08-25 | 2016-03-03 | 日東電工株式会社 | Sample sampling material for high-performance liquid chromatography |
| CN104569187A (en) * | 2014-12-17 | 2015-04-29 | 深圳出入境检验检疫局食品检验检疫技术中心 | Detection method and device for whitening and freckle-removing components in cosmetics |
| CN205643258U (en) * | 2016-03-17 | 2016-10-12 | 广东华鑫检测技术有限公司 | Chromatographic analyzer |
| CN206248622U (en) * | 2016-11-17 | 2017-06-13 | 广州大澳化妆品有限公司 | The testing equipment of IPBC in a kind of cosmetics |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109061079A (en) * | 2018-06-12 | 2018-12-21 | 合肥丰洁生物科技有限公司 | A kind of cosmetics experiment detection device |
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Application publication date: 20180223 |