CN107714597A - A kind of skin whitening, moisturizing Essence and preparation method thereof - Google Patents
A kind of skin whitening, moisturizing Essence and preparation method thereof Download PDFInfo
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- CN107714597A CN107714597A CN201710879531.6A CN201710879531A CN107714597A CN 107714597 A CN107714597 A CN 107714597A CN 201710879531 A CN201710879531 A CN 201710879531A CN 107714597 A CN107714597 A CN 107714597A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention discloses a kind of skin whitening, moisturizing Essence and preparation method thereof, is related to cosmetic technical field, includes the raw material of following parts by weight：10 20 parts of Radix Angelicae Sinensis, 10 20 parts of the root of herbaceous peony, 7 15 parts of white orchid, 7 15 parts of radix ampelopsis, 10 20 parts of Poria cocos, 15 25 parts of the tuber of dwarf lilyturf, 10 20 parts of lily, 10 20 parts of the bighead atractylodes rhizome, 5 15 parts of stiff silkworm, windproof 5 15 parts, 5 15 parts of BAILIANRUI；Preparation method includes：It is prepared by pretreatment of raw material, crushing, water extraction, concentration, decolouring and Essence.The present invention is pure Chinese medicinal preparation, and formula is reasonable, is compounded using plurality of Chinese, Synergistic, stimulate circulation, improve skin metabolism, remove free radical, damaged cell is repaired, expands skin pore, supplements cytotrophy composition, and the Essence good penetrability, functional component can improve cell immunocompetent inside deep enough skin, skin whitening, moisturizing, desalination microgroove, improve the glossy degree of skin so that skin is tender, it is smooth, go to wrinkle, long-term use, skin is delicate in vain, high resilience.
Description
Technical field
The present invention relates to cosmetic technical field, more particularly to a kind of skin whitening, moisturizing Essence and preparation method thereof.
Background technology
Because environment influences, and the growth at people's age, cell itself renewal gradually slows down or cell growth disproportionation, makes
Into the aging of skin.Main clinical manifestation is wrinkle of skin, coarse, dry, loose, pigmentation etc..Conventional skin care master
If preventing ultraviolet light to skin injury, or good nutrient environment is provided for skin, such as all kinds of collagens, hyaluronic acid
Deng, by improve skin growth in environment, promote cell growth, so as to substitute aging problem cell, skin is kept for a long time
The state of health.Essence is the superfine product in skin care item, and its composition is exquisite, effect is powerful, significant effect, remains that it is gathered around
What is had is noble and mysterious, suitable for any skin or inclined oily skin, preferably puts in the vial, takes at any time.Essence is used to feel well
After skin water, before face cream.
At present, in the market also emerges various Essences, the problems such as poor permeability, be not easy to absorb commonly be present, and whitening is protected
Wet effect and inapparent present situation.Although some Essence effects are pretty good, nutritional ingredient has many macromolecular structures, Essence
Being coated on skin needs the long period to be absorbed, and Essence on the market is largely first containing heavy metals such as lead, mercury at present
Although element, the purpose of skin care are to be temporarily reached, but can produce injury to human body.For the toxicity and thorn to chemical toilet
Swashing the doubt of property, increasing scientific researcher tends to find safe and efficient whitening active material from natural plants,
So as to develop whitening effect obvious, action temperature and, the cosmetics of nontoxic nonirritant Chinese herbal medicine and natural plant composition, I
National expenditures Chinese herbal treatment and the various disease of skin of nursing are with a history of thousands of years.
The content of the invention
Based on technical problem existing for background technology, the present invention proposes a kind of skin whitening, moisturizing Essence and its preparation side
Method, obtained Essence good penetrability, functional component can be inside deep enough skins so that skin is tender, it is smooth, go to wrinkle.
A kind of skin whitening, moisturizing Essence proposed by the present invention, include the raw material of following parts by weight：Radix Angelicae Sinensis 10-20 parts, the root of herbaceous peony
10-20 parts, white orchid 7-15 parts, radix ampelopsis 7-15 parts, Poria cocos 10-20 parts, tuber of dwarf lilyturf 15-25 part, lily 10-20 parts, bighead atractylodes rhizome 10-20
Part, stiff silkworm 5-15 parts, windproof 5-15 parts, BAILIANRUI 5-15 parts.
Preferably, the raw material of following parts by weight is included：Radix Angelicae Sinensis 10-15 parts, root of herbaceous peony 13-18 parts, white orchid 10-15 parts, radix ampelopsis
10-15 parts, Poria cocos 13-18 parts, tuber of dwarf lilyturf 17-22 part, lily 10-15 parts, bighead atractylodes rhizome 10-15 parts, stiff silkworm 7-12 parts, windproof 7-12
Part, BAILIANRUI 8-13 parts.
Preferably, the raw material of following parts by weight is included：12 parts of Radix Angelicae Sinensis, 15 parts of the root of herbaceous peony, 12 parts of white orchid, 12 parts of radix ampelopsis, Poria cocos
15 parts, 20 parts of the tuber of dwarf lilyturf, 12 parts of lily, 12 parts of the bighead atractylodes rhizome, 10 parts of stiff silkworm, windproof 10 parts, 10 parts of BAILIANRUI.
The invention also provides the preparation method of above-mentioned skin whitening, moisturizing Essence, comprise the following steps：
(1) pretreatment of raw material：
Radix Angelicae Sinensis crude drug is taken, removes impurity, is cleaned, is run through with light salt brine, be divided into Radix Angelicae Sinensis body and Radix Angelicae Sinensis tail, cut into slices respectively,
Dry；
Root of herbaceous peony crude drug is taken, removes impurity, is cleaned, yellow rice wine is added and mixes vexed profit thoroughly, wheat bran is spread in hot pot, has waited cigarette to emit
It when going out, then will be added through the vexed root of herbaceous peony moistened, and constantly stir-frying, be in faint yellow to root of herbaceous peony surface, weed out wheat bran, cool；
Lily crude drug is taken, removes impurity, net ash bits is shone, dries, then run through, be placed in hot pot with thin rice gruel, slow fire adds
Heat, when frying to color burn, refined honey that addition was diluted with certain amount of boiling water, rapid stir-frying is uniform, and continues to be fried to micro- with slow fire
Yellow, when tack-free, taking-up is dried in the air cool；
Stiff silkworm crude drug is taken, removes impurity and residual silk, is cleaned, is dried, obtain net stiff silkworm, take wheat bran to be sprinkled upon in hot pot, intense fire
Heating, when smoldering, adds net stiff silkworm, frying surface is in yellow, weeds out wheat bran, cools；
(2) crush：Step (1) is pretreated by the pretreated Radix Angelicae Sinensis of step (1), the root of herbaceous peony, lily, stiff silkworm, with
And white orchid, radix ampelopsis, Poria cocos, the tuber of dwarf lilyturf, the bighead atractylodes rhizome, windproof, BAILIANRUI, pulverization process is carried out, mixing, obtains mixed powder；
(3) water extraction：Mixed powder is soaked in water, then intense fire is boiled, is cooked by slow fire, and filtering, obtains extract solution；
(4) concentrate：Extract solution is concentrated under reduced pressure, obtains concentrate；
(5) decolourize：Activated carbon is added to concentrate, stirring, stewing process, filtering, obtains destainer；
(6) prepared by Essence：Preservative is added into destainer, produces skin whitening, moisturizing Essence.
Preferably, in the step (2), 60-100 mesh sieves be crushed.
Preferably, in the step (3), 2-4 times of water immersion 20-40min is added into mixed powder, is then added water
To 10-15 times of water, intense fire is boiled, is cooked by slow fire 4-5h, filtering, obtains extract solution.
Preferably, the filtering is filtered using 150-200 mesh filter screens.
Preferably, in the step (4), the dry matter content in concentrate is 50-150mg/g.
Preferably, in the step (5), activated carbon is added, 20-30min is stirred with 400-700r/min mixing speed,
Then 3-5h is stood.
Application method：After toner, before face cream, face skin is uniformly applied to.
It is as follows the effect of each raw medicinal material in the present invention：
Radix Angelicae Sinensis：It is warm-natured, sweet, pungent, return liver warp, the heart channel of Hang-Shaoyin, the spleen channel, there are replenishing and activating blood, menstruction regulating and pain relieving, the work(to relax bowel
Effect；Modern medicine research confirms, the main component of Radix Angelicae Sinensis is a variety of organic acids, lipid, sugar, several amino acids, trace element with
And more than totally 80 kinds of chemical substance, its volatile oil are mainly Ligustilide, n-butene base Moo lactones and Radix Angelicae Sinensis to other organic principles etc.
Ketone etc., forulic acid are the active ingredient of Radix Angelicae Sinensis antioxidation, by infringement of a variety of mechanism antagonism free radicals to tissue, to certainly
The gloomy or not magnificent or raw sore swells of complexion caused by base blocks have special efficacy, amino acid in containing 17 in Radix Angelicae Sinensis, and wherein body weight is
Human body can not synthesize and required, and the mine trace element and vitamin that contain can adjust the metabolism of human body, Radix Angelicae Sinensis
It can prevent white hair for cosmetics and suppress melanin generation, eliminate pigmentosa skin speckle, remove acne and whelk.
The root of herbaceous peony：Cold nature, bitter, acid, return liver warp, the spleen channel, there is the effect of smooth liver and relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating；In vain
The main component of Chinese herbaceous peony containing Paeoniflorin, Hydroxy peoniflorin, benzoylpaeoniflorin, albiflorin, oxypaeoniflorin, albiflorin, often
Spring rattan sapogenin, Chinese herbaceous peony aglycon ketone, galloylpaeoniflorin, Kaempferol ,-O- the β of 7- bis--D-Glucose glycosides, daucosterol, β-
Sitosterol, Chinese herbaceous peony lactose ketone etc., mainly containing benzoic acid, paeonol etc. in volatile oil；The root of herbaceous peony, which has, removes free radical, oxidation resistant work
With mediation gas, conditioning the five internal organs, so as to whitening spot-removing.
White orchid：It is warm-natured, it is bitter, pungent, return lung warp, stomach, there is cough-relieving, change the effect of turbid；White orchid leaf is containing alkaloid, volatilization
Oil, phenols.Fresh leaf oil-containing 0.7%, oily main component are linalool, methyleugenol and benzyl carbinol, and root and stem skin contain gold zone
Set peaceful alkali, oxoushinsunine, salicifoline and michelalbine；White orchid extract can the brilliant white colour of skin, improve skin
The problems such as dim Huang, colour of skin inequality.
Radix ampelopsis：Cold nature, bitter, thoughts of returning home warp, stomach, there is the effect of clearing heat and detoxicating, carbuncle that disappears dissipating bind；Radix ampelopsis main component contains
Tartaric acid, fumaric acid, Quercetin, resveratrol, rheum emodin, α-spinach sterol, protocatechuic acid, tannin, flavonoid glycoside, glucose
Deng another mucous matter, starch；Radix Ampelopsis extract has strong antibiotic property and anti-inflammatory, effective to suppurative skin infection, can use
In the making of the cosmetics such as acne, there is inhibitory action to black cell activity, be good whitening additive, Radix Ampelopsis extract pair
Radix Ampelopsis extract has inhibitory action to show 5α-reductase, he to because male sex hormone is vigorous and alopecia has preventive and therapeutic effect, also may be used
Promote natural on-off cycles of hair growth in product for improving hair-growing.
Poria cocos：It is mild-natured, it is sweet, light, thoughts of returning home warp, lung channel, the spleen channel, kidney channel, there is the effect of clearing damp and promoting diuresis, invigorating the spleen calming heart；Fu
Siberian cocklebur main component carboxylic acid containing triterpene, there are pachymic acid, soil not sour, loose Siberian cocklebur eo-acid of acid, the lonely L bacterium of tooth, loose Siberian cocklebur etc., also contain polysaccharide,
Predominantly pachyman, in addition, still containing histidine, adenine, choline, β-pachyman enzyme, protease, aliphatic acid, fat,
Lecithin, ergosterol, su-fuling, Poria cocos eo-acid, the loose Siberian cocklebur acid of 3- hydrogenations, the β -ol of ergot steroid -7,22- diene -3,7,9 (11) are gone
The compositions such as hydrogen pachymic acid；Poria cocos being capable of dispelling speckles and whitening face, moist skin, moreover it is possible to strengthens immunologic function, expands blood vessel.
The tuber of dwarf lilyturf：Cold nature, sweet, slight bitter, thoughts of returning home warp, lung channel, stomach, there is the effect of nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire；The tuber of dwarf lilyturf
Main component contain a variety of steroid saponins, wherein Ophiopogonin A content highest, ophiopogonin B takes second place, in addition containing a variety of Gao Yihuang
Ketone compounds, separately also A containing ophiopogonone, Lu Si can soap former times member, diosgenin, ophiopogon flavonoid, α-patchoulene, 16
Alkanoic acid ethyl ester, oleanolic acid etc.；Ophiopogon japonicus extract is acted on superoxide anion and Qiang base Zi You Yuan eliminations, available for cosmetics
Anti-aging.
Lily：It is cold in nature, it is sweet, thoughts of returning home warp, lung channel, there is the effect of Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing；The main component of lily contains
Ming River lily glycosides, remove acyl Lilium brownie, daucosterol, remove acyl Lilium brownie, Lilium brownie, β-solamargine, 1-O- to tonka-bean
Acyl glycerine, slave's Ah's sapogenin etc.；Lily is used for cosmetics, the polysaccharide Wheat Protein in its composition, removes hydroxy radical,
SOD vigor is improved, activated protein composition can promote cell metabolism, repair damaged skin, water conservation moisturizing.
The bighead atractylodes rhizome：It is warm-natured, it is sweet, bitter, returns spleen warp, stomach, there is the effect of invigorating the spleen, QI invigorating, eliminate dampness and have diuretic effect, hidroschesis；In the bighead atractylodes rhizome
Mainly contain volatile oil atractylone, and cypress polysaccharide-mannosan AM-3, there is immunological enhancement, also containing α-Humuleno,
The compositions such as carypohyllene, eucalyptol, biatractylolide, Scopoletin, γ-sterol；The bighead atractylodes rhizome has special efficacy for skin whitening, and it is to skin
For example vaporific Epidermophyton of skin pathomycete etc. has inhibitory action.
Stiff silkworm：Mild-natured, taste is salty, pungent, return liver warp, lung channel, stomach, there is the effect of dispelling wind and relieving convulsion, reducing phlegm and resolving masses；The master of stiff silkworm
Composition is wanted containing protein, amino acid, fat, ecdysterone and beauvericin etc.；Stiff silkworm has eliminating chloasma, changes senile plaque expelling, shines
The effect of spot.
It is windproof：It is warm-natured, it is sweet, pungent, return bladder warp, Liver Channel, the spleen channel, deliver, wind-dispelling, dehumidifying the effect of；Windproof garment will
Composition contains volatile oil, there is 20 kinds of compounds in oil, content it is higher have octanal, β-bisabolence, macrotin glycosides, β-piper cubeba
Alkene, windproof chromone alcohol, hamaudol, macrotin, methyl eugenol, nopinene, deltoin, windproof acidic polysaccharose, sickleleaf celery two
Alcohol, vanillic acid, Panaxynol (relative amount 82.6%), in addition containing chromone, cumarin, polyacetylene class, polysaccharide etc.
Composition；It is windproof that there is anti-inflammatory, antibacterial, antiallergic effect, the allergic phenomena during cosmetics use can be alleviated.
BAILIANRUI：It is mild-natured, sweet, puckery, thoughts of returning home warp, kidney channel, have clear away heart-fire, kidney-nourishing, it is puckery essence, hemostasis the effect of；In BAILIANRUI
Containing Quercetin, cyanidenon, Isoquercitrin, cyanidenon glycoside, contain alkaloid again；BAILIANRUI can make skin ruddy,
Happy color.
Beneficial effect：The present invention is pure Chinese medicinal preparation, and formula is reasonable, is compounded using plurality of Chinese, Synergistic, is promoted
Enter blood circulation, improve skin metabolism, remove free radical, repair damaged cell, expand skin pore, supplement cytotrophy
Composition, and the Essence good penetrability, functional component can improve cell immunocompetent inside deep enough skin, skin whitening, moisturizing, light
Change microgroove, improve the glossy degree of skin so that skin is tender, it is smooth, go to wrinkle, long-term use of, skin is delicate in vain, high resilience.
Embodiment
Below, technical scheme is described in detail by specific embodiment.
Embodiment 1
A kind of skin whitening, moisturizing Essence proposed by the present invention, include the raw material of following parts by weight：10 parts of Radix Angelicae Sinensis, the root of herbaceous peony 20
Part, 7 parts of white orchid, 15 parts of radix ampelopsis, 10 parts of Poria cocos, 25 parts of the tuber of dwarf lilyturf, 10 parts of lily, 20 parts of the bighead atractylodes rhizome, 5 parts of stiff silkworm, windproof 15 parts, white lotus
5 parts of stamen.
The invention also provides the preparation method of above-mentioned skin whitening, moisturizing Essence, comprise the following steps：
(1) pretreatment of raw material：
Radix Angelicae Sinensis crude drug is taken, removes impurity, is cleaned, is run through with light salt brine, be divided into Radix Angelicae Sinensis body and Radix Angelicae Sinensis tail, cut into slices respectively,
Dry；
Root of herbaceous peony crude drug is taken, removes impurity, is cleaned, yellow rice wine is added and mixes vexed profit thoroughly, wheat bran is spread in hot pot, has waited cigarette to emit
It when going out, then will be added through the vexed root of herbaceous peony moistened, and constantly stir-frying, be in faint yellow to root of herbaceous peony surface, weed out wheat bran, cool；
Lily crude drug is taken, removes impurity, net ash bits is shone, dries, then run through, be placed in hot pot with thin rice gruel, slow fire adds
Heat, when frying to color burn, refined honey that addition was diluted with certain amount of boiling water, rapid stir-frying is uniform, and continues to be fried to micro- with slow fire
Yellow, when tack-free, taking-up is dried in the air cool；
Stiff silkworm crude drug is taken, removes impurity and residual silk, is cleaned, is dried, obtain net stiff silkworm, take wheat bran to be sprinkled upon in hot pot, intense fire
Heating, when smoldering, adds net stiff silkworm, frying surface is in yellow, weeds out wheat bran, cools；
(2) crush：Step (1) is pretreated by the pretreated Radix Angelicae Sinensis of step (1), the root of herbaceous peony, lily, stiff silkworm, with
And white orchid, radix ampelopsis, Poria cocos, the tuber of dwarf lilyturf, the bighead atractylodes rhizome, windproof, BAILIANRUI, pulverization process is carried out, mixing, obtains mixed powder；
(3) water extraction：Mixed powder is soaked in water, then intense fire is boiled, is cooked by slow fire, and filtering, obtains extract solution；
(4) concentrate：Extract solution is concentrated under reduced pressure, obtains concentrate；
(5) decolourize：Activated carbon is added to concentrate, stirring, stewing process, filtering, obtains destainer；
(6) prepared by Essence：Preservative is added into destainer, produces skin whitening, moisturizing Essence.
Embodiment 2
A kind of skin whitening, moisturizing Essence proposed by the present invention, include the raw material of following parts by weight：10 parts of Radix Angelicae Sinensis, the root of herbaceous peony 18
It is part, 10 parts of white orchid, 15 parts of radix ampelopsis, 13 parts of Poria cocos, 22 parts of the tuber of dwarf lilyturf, 10 parts of lily, 15 parts of the bighead atractylodes rhizome, 7 parts of stiff silkworm, windproof 12 parts, white
8 parts of lotus stamen.
The invention also provides the preparation method of above-mentioned skin whitening, moisturizing Essence, comprise the following steps：
(1) pretreatment of raw material：
Radix Angelicae Sinensis crude drug is taken, removes impurity, is cleaned, is run through with light salt brine, be divided into Radix Angelicae Sinensis body and Radix Angelicae Sinensis tail, cut into slices respectively,
Dry；
Root of herbaceous peony crude drug is taken, removes impurity, is cleaned, yellow rice wine is added and mixes vexed profit thoroughly, wheat bran is spread in hot pot, has waited cigarette to emit
It when going out, then will be added through the vexed root of herbaceous peony moistened, and constantly stir-frying, be in faint yellow to root of herbaceous peony surface, weed out wheat bran, cool；
Lily crude drug is taken, removes impurity, net ash bits is shone, dries, then run through, be placed in hot pot with thin rice gruel, slow fire adds
Heat, when frying to color burn, refined honey that addition was diluted with certain amount of boiling water, rapid stir-frying is uniform, and continues to be fried to micro- with slow fire
Yellow, when tack-free, taking-up is dried in the air cool；
Stiff silkworm crude drug is taken, removes impurity and residual silk, is cleaned, is dried, obtain net stiff silkworm, take wheat bran to be sprinkled upon in hot pot, intense fire
Heating, when smoldering, adds net stiff silkworm, frying surface is in yellow, weeds out wheat bran, cools；
(2) crush：Step (1) is pretreated by the pretreated Radix Angelicae Sinensis of step (1), the root of herbaceous peony, lily, stiff silkworm, with
And white orchid, radix ampelopsis, Poria cocos, the tuber of dwarf lilyturf, the bighead atractylodes rhizome, windproof, BAILIANRUI, carry out crushed the mixing of 60 mesh sieves, obtain mixed powder；
(3) water extraction：2 times of water immersion 20min is added into mixed powder, then adds water to 10 times of waters, intense fire and burns
Open, be cooked by slow fire 4h, filtered using 150 mesh filter screens, obtain extract solution
(4) concentrate：It is 50mg/g that extract solution, which is carried out being concentrated under reduced pressure into dry matter content, obtains concentrate；
(5) decolourize：Activated carbon is added to concentrate, 20min is stirred with 400r/min mixing speed, then stands 3h,
Filtering, obtains destainer；
(6) prepared by Essence：Preservative is added into destainer, produces skin whitening, moisturizing Essence.
Embodiment 3
A kind of skin whitening, moisturizing Essence proposed by the present invention, include the raw material of following parts by weight：14 parts of Radix Angelicae Sinensis, the root of herbaceous peony 16
Part, 13 parts of white orchid, 13 parts of radix ampelopsis, 16 parts of Poria cocos, 19 parts of the tuber of dwarf lilyturf, 14 parts of lily, 13 parts of the bighead atractylodes rhizome, 9 parts of stiff silkworm, windproof 9 parts, white lotus
11 parts of stamen.
The invention also provides the preparation method of above-mentioned skin whitening, moisturizing Essence, comprise the following steps：
(1) pretreatment of raw material：
Radix Angelicae Sinensis crude drug is taken, removes impurity, is cleaned, is run through with light salt brine, be divided into Radix Angelicae Sinensis body and Radix Angelicae Sinensis tail, cut into slices respectively,
Dry；
Root of herbaceous peony crude drug is taken, removes impurity, is cleaned, yellow rice wine is added and mixes vexed profit thoroughly, wheat bran is spread in hot pot, has waited cigarette to emit
It when going out, then will be added through the vexed root of herbaceous peony moistened, and constantly stir-frying, be in faint yellow to root of herbaceous peony surface, weed out wheat bran, cool；
Lily crude drug is taken, removes impurity, net ash bits is shone, dries, then run through, be placed in hot pot with thin rice gruel, slow fire adds
Heat, when frying to color burn, refined honey that addition was diluted with certain amount of boiling water, rapid stir-frying is uniform, and continues to be fried to micro- with slow fire
Yellow, when tack-free, taking-up is dried in the air cool；
Stiff silkworm crude drug is taken, removes impurity and residual silk, is cleaned, is dried, obtain net stiff silkworm, take wheat bran to be sprinkled upon in hot pot, intense fire
Heating, when smoldering, adds net stiff silkworm, frying surface is in yellow, weeds out wheat bran, cools；
(2) crush：Step (1) is pretreated by the pretreated Radix Angelicae Sinensis of step (1), the root of herbaceous peony, lily, stiff silkworm, with
And white orchid, radix ampelopsis, Poria cocos, the tuber of dwarf lilyturf, the bighead atractylodes rhizome, windproof, BAILIANRUI, carry out crushed the mixing of 70 mesh sieves, obtain mixed powder；
(3) water extraction：3 times of water immersion 25min is added into mixed powder, then adds water to 12 times of waters, intense fire and burns
Open, be cooked by slow fire 4.5h, filtered using 180 mesh filter screens, obtain extract solution
(4) concentrate：It is 100mg/g that extract solution, which is carried out being concentrated under reduced pressure into dry matter content, obtains concentrate；
(5) decolourize：Activated carbon is added to concentrate, 25min is stirred with 500r/min mixing speed, then stood
3.5h, filtering, obtains destainer；
(6) prepared by Essence：Preservative is added into destainer, produces skin whitening, moisturizing Essence.
Embodiment 4
A kind of skin whitening, moisturizing Essence proposed by the present invention, include the raw material of following parts by weight：12 parts of Radix Angelicae Sinensis, the root of herbaceous peony 15
It is part, 12 parts of white orchid, 12 parts of radix ampelopsis, 15 parts of Poria cocos, 20 parts of the tuber of dwarf lilyturf, 12 parts of lily, 12 parts of the bighead atractylodes rhizome, 10 parts of stiff silkworm, windproof 10 parts, white
10 parts of lotus stamen.
The invention also provides the preparation method of above-mentioned skin whitening, moisturizing Essence, comprise the following steps：
(1) pretreatment of raw material：
Radix Angelicae Sinensis crude drug is taken, removes impurity, is cleaned, is run through with light salt brine, be divided into Radix Angelicae Sinensis body and Radix Angelicae Sinensis tail, cut into slices respectively,
Dry；
Root of herbaceous peony crude drug is taken, removes impurity, is cleaned, yellow rice wine is added and mixes vexed profit thoroughly, wheat bran is spread in hot pot, has waited cigarette to emit
It when going out, then will be added through the vexed root of herbaceous peony moistened, and constantly stir-frying, be in faint yellow to root of herbaceous peony surface, weed out wheat bran, cool；
Lily crude drug is taken, removes impurity, net ash bits is shone, dries, then run through, be placed in hot pot with thin rice gruel, slow fire adds
Heat, when frying to color burn, refined honey that addition was diluted with certain amount of boiling water, rapid stir-frying is uniform, and continues to be fried to micro- with slow fire
Yellow, when tack-free, taking-up is dried in the air cool；
Stiff silkworm crude drug is taken, removes impurity and residual silk, is cleaned, is dried, obtain net stiff silkworm, take wheat bran to be sprinkled upon in hot pot, intense fire
Heating, when smoldering, adds net stiff silkworm, frying surface is in yellow, weeds out wheat bran, cools；
(2) crush：Step (1) is pretreated by the pretreated Radix Angelicae Sinensis of step (1), the root of herbaceous peony, lily, stiff silkworm, with
And white orchid, radix ampelopsis, Poria cocos, the tuber of dwarf lilyturf, the bighead atractylodes rhizome, windproof, BAILIANRUI, carry out crushed the mixing of 80 mesh sieves, obtain mixed powder；
(3) water extraction：3 times of water immersion 30min is added into mixed powder, then adds water to 13 times of waters, intense fire and burns
Open, be cooked by slow fire 4.5h, filtered using 180 mesh filter screens, obtain extract solution
(4) concentrate：It is 120mg/g that extract solution, which is carried out being concentrated under reduced pressure into dry matter content, obtains concentrate；
(5) decolourize：Activated carbon is added to concentrate, 25min is stirred with 600r/min mixing speed, then stands 4h,
Filtering, obtains destainer；
(6) prepared by Essence：Preservative is added into destainer, produces skin whitening, moisturizing Essence.
Embodiment 5
A kind of skin whitening, moisturizing Essence proposed by the present invention, include the raw material of following parts by weight：20 parts of Radix Angelicae Sinensis, the root of herbaceous peony 10
Part, 15 parts of white orchid, 7 parts of radix ampelopsis, 20 parts of Poria cocos, 15 parts of the tuber of dwarf lilyturf, 20 parts of lily, 10 parts of the bighead atractylodes rhizome, 15 parts of stiff silkworm, windproof 5 parts, white lotus
15 parts of stamen.
The invention also provides the preparation method of above-mentioned skin whitening, moisturizing Essence, comprise the following steps：
(1) pretreatment of raw material：
Radix Angelicae Sinensis crude drug is taken, removes impurity, is cleaned, is run through with light salt brine, be divided into Radix Angelicae Sinensis body and Radix Angelicae Sinensis tail, cut into slices respectively,
Dry；
Root of herbaceous peony crude drug is taken, removes impurity, is cleaned, yellow rice wine is added and mixes vexed profit thoroughly, wheat bran is spread in hot pot, has waited cigarette to emit
It when going out, then will be added through the vexed root of herbaceous peony moistened, and constantly stir-frying, be in faint yellow to root of herbaceous peony surface, weed out wheat bran, cool；
Lily crude drug is taken, removes impurity, net ash bits is shone, dries, then run through, be placed in hot pot with thin rice gruel, slow fire adds
Heat, when frying to color burn, refined honey that addition was diluted with certain amount of boiling water, rapid stir-frying is uniform, and continues to be fried to micro- with slow fire
Yellow, when tack-free, taking-up is dried in the air cool；
Stiff silkworm crude drug is taken, removes impurity and residual silk, is cleaned, is dried, obtain net stiff silkworm, take wheat bran to be sprinkled upon in hot pot, intense fire
Heating, when smoldering, adds net stiff silkworm, frying surface is in yellow, weeds out wheat bran, cools；
(2) crush：Step (1) is pretreated by the pretreated Radix Angelicae Sinensis of step (1), the root of herbaceous peony, lily, stiff silkworm, with
And white orchid, radix ampelopsis, Poria cocos, the tuber of dwarf lilyturf, the bighead atractylodes rhizome, windproof, BAILIANRUI, carry out crushed the mixing of 100 mesh sieves, obtain mixed powder；
(3) water extraction：4 times of water immersion 40min is added into mixed powder, then adds water to 15 times of waters, intense fire and burns
Open, be cooked by slow fire 5h, filtered using 200 mesh filter screens, obtain extract solution
(4) concentrate：It is 150mg/g that extract solution, which is carried out being concentrated under reduced pressure into dry matter content, obtains concentrate；
(5) decolourize：Activated carbon is added to concentrate, 30min is stirred with 700r/min mixing speed, then stands 5h,
Filtering, obtains destainer；
(6) prepared by Essence：Preservative is added into destainer, produces skin whitening, moisturizing Essence.
Embodiment 6
A kind of skin whitening, moisturizing Essence proposed by the present invention, include the raw material of following parts by weight：15 parts of Radix Angelicae Sinensis, the root of herbaceous peony 13
It is part, 15 parts of white orchid, 10 parts of radix ampelopsis, 18 parts of Poria cocos, 17 parts of the tuber of dwarf lilyturf, 15 parts of lily, 10 parts of the bighead atractylodes rhizome, 12 parts of stiff silkworm, windproof 7 parts, white
13 parts of lotus stamen.
The invention also provides the preparation method of above-mentioned skin whitening, moisturizing Essence, with embodiment 5.
Effect assessment is carried out to skin whitening, moisturizing Essence prepared by the present invention.
1st, acute skin safety evaluatio
Healthy guinea pig 30 is chosen, six groups is randomly divided into, every group 5, is respectively used to evaluate whitening prepared by embodiment 1-6
Moisturizing essence；Its back spinal both sides hair is shaved off into 2cmx2cm with battery powered shaver, exposed skin, every group of 5 cavys, divided
It is right on the skin for not taking the left side that 0.2mL, 0.4mL, 0.8mL, 1.6mL, 3.2mL skin whitening, moisturizing Essence is applied to cavy
, per observing whether there are the allergic phenomenas such as redness around each experimental group skin every other hour, used as blank control after 24 hours side
Warm water washes away, and observes change of skin.
In this experiment, six groups of cavys do not observe systemic toxicity profiles performance, the skin of recipient site on all time points
Skin is also without allergic phenomena, left side unhairing area skin outward appearance and color and luster etc. and right sides one such as skin temperature rise, erythema and oedema
Cause, illustrate the skin whitening, moisturizing Essence of the invention prepared to skin without obvious irritation and acute toxicity.
2nd, chronic skin safety evaluatio
Healthy guinea pig 30 is chosen, six groups is randomly divided into, every group 5, is respectively used to evaluate whitening prepared by embodiment 1-6
Moisturizing essence；Its back spinal both sides hair is shaved off into 2cmx2cm with battery powered shaver, exposed skin, every group of 5 cavys, taken
1mL skin whitening, moisturizing Essence is applied on the skin in the left side of cavy, and right side is smeared 3 times, held altogether as blank control daily
Continuous administration 14 days.0th, the 7th and the 14th day, observe its change of skin situation.
In this experiment, six groups of cavys were at the 7th and the 14th day, and the skin of recipient site is without skin temperature rise, erythema
With the allergic phenomena such as oedema, left side unhairing area skin outward appearance and color and luster etc. are consistent with right side, the state of mind and diet without
Significant change, illustrate the skin whitening, moisturizing Essence of the invention prepared to skin without obvious irritation and chronic toxicity.
3rd, stability test
Skin whitening, moisturizing Essence prepared by 1-6 of the embodiment of the present invention is placed 12 months at room temperature, it is obvious heavy to there are no
Form sediment.
4th, human body applicating evaluating
Crowd selects：Age 20-50 year is selected, face has obscure, dry tarnish of different degrees of pigmentation, skin etc.
100 women of skin problem, exclude with serious systemic disease, immune deficiency, autoimmune disease；Experimenter's daily morning and evening
After face cleaning, according to the basic cosmetics nursing skin usually used, skin whitening, moisturizing Essence prepared by the embodiment of the present invention 4 is used
After toner, before face cream, it is used continuously one month.
Use result：The skin for having 75% experimenter has obvious dark yellow regression, skin is moistened, and has 21% experimenter
Skin makes moderate progress, and skin is pale than before, and effective percentage does not occur the symptom such as allergic up to 96% in tested 100 people.Should
As a result show, skin whitening, moisturizing Essence of the invention has the effect of good skin whitening, moisturizing.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto,
Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its
Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.
Claims (9)
1. a kind of skin whitening, moisturizing Essence, it is characterised in that include the raw material of following parts by weight：Radix Angelicae Sinensis 10-20 parts, root of herbaceous peony 10-
20 parts, white orchid 7-15 parts, radix ampelopsis 7-15 parts, Poria cocos 10-20 parts, tuber of dwarf lilyturf 15-25 part, lily 10-20 parts, bighead atractylodes rhizome 10-20 parts, deadlock
Silkworm 5-15 parts, windproof 5-15 parts, BAILIANRUI 5-15 parts.
2. skin whitening, moisturizing Essence according to claim 1, it is characterised in that include the raw material of following parts by weight：Radix Angelicae Sinensis
10-15 parts, root of herbaceous peony 13-18 parts, white orchid 10-15 parts, radix ampelopsis 10-15 parts, Poria cocos 13-18 parts, tuber of dwarf lilyturf 17-22 part, lily 10-15
Part, bighead atractylodes rhizome 10-15 parts, stiff silkworm 7-12 parts, windproof 7-12 parts, BAILIANRUI 8-13 parts.
3. skin whitening, moisturizing Essence according to claim 1, it is characterised in that include the raw material of following parts by weight：Radix Angelicae Sinensis
12 parts, 15 parts of the root of herbaceous peony, 12 parts of white orchid, 12 parts of radix ampelopsis, 15 parts of Poria cocos, 20 parts of the tuber of dwarf lilyturf, 12 parts of lily, 12 parts of the bighead atractylodes rhizome, 10 parts of stiff silkworm,
Windproof 10 parts, 10 parts of BAILIANRUI.
A kind of 4. preparation method based on any described skin whitening, moisturizing Essences of claim 1-3, it is characterised in that including with
Lower step：
(1) pretreatment of raw material：
Radix Angelicae Sinensis crude drug is taken, removes impurity, is cleaned, is run through with light salt brine, be divided into Radix Angelicae Sinensis body and Radix Angelicae Sinensis tail, cut into slices respectively, is dried；
Root of herbaceous peony crude drug is taken, removes impurity, is cleaned, yellow rice wine is added and mixes vexed profit thoroughly, wheat bran is spread in hot pot, has waited cigarette to emerge
When, then will be added through the vexed root of herbaceous peony moistened, constantly stir-frying, it is in faint yellow to root of herbaceous peony surface, weeds out wheat bran, cool；
Lily crude drug is taken, removes impurity, net ash bits is shone, dries, then run through, be placed in hot pot with thin rice gruel, slow fire heating, fry
During to color burn, refined honey that addition was diluted with certain amount of boiling water, rapid stir-frying is uniform, and continues to be fried to slightly yellow with slow fire,
When tack-free, taking-up is dried in the air cool；
Stiff silkworm crude drug is taken, removes impurity and residual silk, is cleaned, is dried, obtain net stiff silkworm, take wheat bran to be sprinkled upon in hot pot, intense fire heating,
When smoldering, net stiff silkworm is added, frying surface is in yellow, weeds out wheat bran, cools；
(2) crush：Step (1) is pretreated by the pretreated Radix Angelicae Sinensis of step (1), the root of herbaceous peony, lily, stiff silkworm, Yi Jibai
Orchid, radix ampelopsis, Poria cocos, the tuber of dwarf lilyturf, the bighead atractylodes rhizome, windproof, BAILIANRUI, pulverization process is carried out, mixing, obtains mixed powder；
(3) water extraction：Mixed powder is soaked in water, then intense fire is boiled, is cooked by slow fire, and filtering, obtains extract solution；
(4) concentrate：Extract solution is concentrated under reduced pressure, obtains concentrate；
(5) decolourize：Activated carbon is added to concentrate, stirring, stewing process, filtering, obtains destainer；
(6) prepared by Essence：Preservative is added into destainer, produces skin whitening, moisturizing Essence.
5. the preparation method of skin whitening, moisturizing Essence according to claim 4, it is characterised in that in the step (2), powder
It is broken to cross 60-100 mesh sieves.
6. the preparation method of skin whitening, moisturizing Essence according to claim 4, it is characterised in that in the step (3), to
2-4 times of water immersion 20-40min is added in mixed powder, is then added water to 10-15 times of water, intense fire is boiled, is cooked by slow fire
4-5h, filtering, obtains extract solution.
7. the preparation method of skin whitening, moisturizing Essence according to claim 6, it is characterised in that the filtering uses 150-
200 mesh filter screens are filtered.
8. the preparation method of skin whitening, moisturizing Essence according to claim 4, it is characterised in that dense in the step (4)
Dry matter content in contracting liquid is 50-150mg/g.
9. the preparation method of skin whitening, moisturizing Essence according to claim 4, it is characterised in that in the step (5), add
Enter activated carbon, 20-30min is stirred with 400-700r/min mixing speed, then stands 3-5h.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110876709A (en) * | 2019-11-25 | 2020-03-13 | 无锡宾西利悦科技有限公司 | A skin caring composition |
| CN111093612A (en) * | 2017-11-02 | 2020-05-01 | 科玛美保株式会社 | Skin whitening composition comprising beauvericin or beauvericin derivative as active ingredient |
| CN111437231A (en) * | 2020-04-18 | 2020-07-24 | 北温草生物科技(上海)有限公司 | Chinese herbal medicine composition for resisting wrinkles and resisting aging |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101006973A (en) * | 2006-01-26 | 2007-08-01 | 刘孟东 | Nutrition extract for eradicating wrinkles and its preparation method |
| CN104958626A (en) * | 2015-07-15 | 2015-10-07 | 徐东 | Medicine for treating colitis and preparation method thereof |
| CN106389232A (en) * | 2016-11-28 | 2017-02-15 | 墨宝股份有限公司 | Essence for skin care and preparation method thereof |
| CN107095828A (en) * | 2017-07-03 | 2017-08-29 | 四川省中医药科学院 | A kind of daily chemical product composition with skin barrier repair function and its production and use |
| CN107184446A (en) * | 2017-04-25 | 2017-09-22 | 钦州市圆森教育咨询有限公司 | A kind of skin whitening, moisturizing shower cream |
-
2017
- 2017-09-26 CN CN201710879531.6A patent/CN107714597A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101006973A (en) * | 2006-01-26 | 2007-08-01 | 刘孟东 | Nutrition extract for eradicating wrinkles and its preparation method |
| CN104958626A (en) * | 2015-07-15 | 2015-10-07 | 徐东 | Medicine for treating colitis and preparation method thereof |
| CN106389232A (en) * | 2016-11-28 | 2017-02-15 | 墨宝股份有限公司 | Essence for skin care and preparation method thereof |
| CN107184446A (en) * | 2017-04-25 | 2017-09-22 | 钦州市圆森教育咨询有限公司 | A kind of skin whitening, moisturizing shower cream |
| CN107095828A (en) * | 2017-07-03 | 2017-08-29 | 四川省中医药科学院 | A kind of daily chemical product composition with skin barrier repair function and its production and use |
Non-Patent Citations (1)
| Title |
|---|
| 国家执业药师资格考试研究组: "《2016国家执业药师考试百日通关宝典 中药学专业知识(一)》", 31 March 2016, 中国医药科技出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111093612A (en) * | 2017-11-02 | 2020-05-01 | 科玛美保株式会社 | Skin whitening composition comprising beauvericin or beauvericin derivative as active ingredient |
| CN111093612B (en) * | 2017-11-02 | 2022-11-18 | 科玛美保株式会社 | Skin whitening composition comprising beauvericin or beauvericin derivative as active ingredient |
| CN110876709A (en) * | 2019-11-25 | 2020-03-13 | 无锡宾西利悦科技有限公司 | A skin caring composition |
| CN111437231A (en) * | 2020-04-18 | 2020-07-24 | 北温草生物科技(上海)有限公司 | Chinese herbal medicine composition for resisting wrinkles and resisting aging |
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Application publication date: 20180223 |