CN107692238A - Application of the oyster peptide in special medicine purposes formula food is prepared - Google Patents
Application of the oyster peptide in special medicine purposes formula food is prepared Download PDFInfo
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- CN107692238A CN107692238A CN201710856835.0A CN201710856835A CN107692238A CN 107692238 A CN107692238 A CN 107692238A CN 201710856835 A CN201710856835 A CN 201710856835A CN 107692238 A CN107692238 A CN 107692238A
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- Prior art keywords
- formula food
- special medicine
- medicine purposes
- vitamin
- purposes formula
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- 235000013305 food Nutrition 0.000 title claims abstract description 71
- 239000003814 drug Substances 0.000 title claims abstract description 48
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 24
- 241000237502 Ostreidae Species 0.000 title claims abstract description 22
- 235000020636 oyster Nutrition 0.000 title claims abstract description 22
- 235000019742 Vitamins premix Nutrition 0.000 claims abstract description 21
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 19
- 239000011707 mineral Substances 0.000 claims abstract description 19
- 239000000126 substance Substances 0.000 claims abstract description 16
- 241000196324 Embryophyta Species 0.000 claims abstract description 11
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- 108090000942 Lactalbumin Proteins 0.000 claims abstract description 11
- 239000000843 powder Substances 0.000 claims abstract description 11
- 238000002360 preparation method Methods 0.000 claims abstract description 11
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/185—Vegetable proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23P10/20—Agglomerating; Granulating; Tabletting
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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Abstract
The invention discloses application of the oyster peptide in special medicine purposes formula food is prepared, and a kind of special medicine purposes formula food for being applied to 1 10 years old crowd and a kind of special medicine purposes formula food for being applied to more than 10 years old crowd and preparation method thereof are disclosed, the formula food includes following components:Soybean protein isolate, lactalbumin, oyster peptide, plant fat powder, maltodextrin, isomalt, FOS, inulin, vitamin premix and mineral substance premix.Special medicine purposes formula food disclosed in this invention contains marine protein oyster peptide, the each component of product and each nutrient comply fully with relevant national standard, fully meet the nutritional need of 1 10 years old and more than 10 years old crowd, and mature preparation process, be easy to industrialize.
Description
Technical field
The present invention relates to food technology field, more particularly to oyster peptide answering in special medicine purposes formula food is prepared
With.
Background technology
Special medicine purposes formula food, " enteral (oral) nutritional preparation " is referred to as in doctors' mouth, is between general
A logical based food between food and medicine, based on powdery or liquid and volume is larger, because its contain various nutritional ingredients with
And nutritional support clinically acts on, the category of food is generally included in the world.A large amount of clinical researches and economics
Research finds that EEN is safe and effective and substantially reduces postoperative complications, hospital stays, medical expense, so as to mitigate
The financial burden of patient, therefore many developed countries are widely used abroad and usage history is long.
The current situation of external special medicine purposes formula food:
European Union formally promulgated FSMP standards (Dietary foods for special medical in 1999
Purpose, 1999/21/EC).Promulgated again in 2001 " can be used in special dietary purpose food can additive name
It is single " (2001/15/EEC), clear stipulaties may be used at the nutriment in FSMP, and intend addition in medical food
New component/new raw material needs to obtain the approval of food security office of European Union (EFSA).For the approval before listing, each member state also exists
The respective specified of this country has been formulated on the basis of EU criteria.Relevant governmental portion is needed before such as Holland, the listing of state of Spain
Door is put on record, and the state such as France, Germany, Poland then requires that enterprise provides data and carries out drug evaluation, the main peace for examining product
Full property and validity, but review procedure is relatively easy, and period under review is generally 3 months.
The U.S. is in 1988 first in Medicine Act revised edition " for medical in Orphan Drug Act Amendments "
Food is explicitly defined.The same year, FDA put into effect the guideline of the production and supervision for medical food first, including produce,
Sampling, examine and the multinomial content such as judge, intend new component/new raw material of the addition in special medicine purposes formula food need into
Row GRAS is assessed, it is not necessary to registration and approval before listing.
Australia/New Zealand Food Rules Committee issues whole on the assessment report of FSMP standards in May, 2012
Original text (Proposal P242), it is not necessary to which the registration approval before listing requires.
The current situation of domestic special medicine purposes formula food:
At present, China's special medicine purposes formula food market is occupied by foreign corporation's product, is supervised by Ministry of Public Health's health
Superintend and direct central tissue and be expounded through peer review import after evaluation.
To meet the needs of clinical patients such as China's diabetes, nephrosis are to special medicine purposes formula food and reducing use
The financial burden of person, China progressively establish correlation in line with international standards while special medicine purposes formula food is developed
Supporting national standard system.On December 21st, 2010, China's issue GB25596-2010《The special doctor of national food safety standard
Learn purposes infant formula general rule》, regulation is made to the medical food of infant within one-year-old.On August 27th, 2012, health
Portion according to《The law of food safety》And its regulation of implementing regulations, organize to set up《National food safety standard special medicine purposes is matched somebody with somebody
Square food general rule (exposure draft)》, the authorizing standard integrates with current international practice standard, focuses on the operability of standard, strictly
Write by national food safety standard requirement.Drafting group collects domestic concerned countries standard, at the same referring also to European Union,
The relevant criterion for the countries such as CODEX, the U.S., Australia is new.On 2 16th, 2013, the Ministry of Public Health was according to GB17405-1998《Health food
Good Manufacture Practice》、《GMP》Etc. implementing regulations, organize to set up《Special medicine purposes formula is eaten
Product Good Manufacture Practice》National food safety standard (exposure draft), on January 10th, 2014, the issue of national health State Family Planning Commission was public
Accuse:According to《People's Republic of China's the law of food safety》With《National food safety standard management method》Regulation, through food security
National standard is evaluated the committee and passed《Special medicine purposes formula food general rule》、《Special medicine purposes formula food is looked forward to
Industry Good Manufacture Practice》.So far, the production of China's special medicine purposes formula food will be evidence-based, rely on for a long time into
The high situation of the few valency of mouth, amount will be broken.
At present, domestic special medicine purposes formula food kind is seldom, and add oyster peptide is even more not have, therefore, exploitation
A kind of special medicine purposes formula food of addition oyster peptide is imperative.
The content of the invention
In order to solve the above technical problems, the invention provides a kind of special medicine purposes formula food, can be divided with reaching
Do not meet the purpose of the nutritional need of 1-10 year crowd and more than 10 years old crowd.
To reach above-mentioned purpose, technical scheme is as follows:
The invention discloses application of the oyster peptide in special medicine purposes formula food is prepared.
A kind of special medicine purposes formula food, including following components:Soybean protein isolate, lactalbumin, oyster peptide, plant
Thing fatty powder, maltodextrin, isomalt, FOS, inulin, vitamin premix and mineral substance premix.Specifically
Including following two special medicine purposes formula foods suitable for different crowd.
A kind of special medicine purposes formula food for being applied to 1-10 year crowd, including following components in parts by weight:
Soybean protein isolate:0~15 part;Lactalbumin:0~15 part;Oyster peptide:0~7 part;Plant fat powder:30~36 parts;Malt
Dextrin:0~66 part;Isomalt:0~20 part;FOS:0~4 part;Inulin:0~4 part;Vitamin premix:0
~2 parts;Mineral substance premix:0~10 part.
A kind of special medicine purposes formula food for being applied to more than 10 years old crowd, including in parts by weight with the following group
Point:Soybean protein isolate:0~17 part;Lactalbumin:0~17 part;Oyster peptide:0~8 part;Plant fat powder:20~30 parts;Wheat
Bud dextrin:0~70 part;Isomalt:0~23 part;FOS:0~4 part;Inulin:0~4 part;Vitamin premix:
0~2 part;Mineral substance premix:0~12 part.
In such scheme, the preparation method of the plant fat powder is:Corn oil and linseed oil are according to 4.4~7.0:1
Ratio mix, after being stirred and evenly mixed with emulsifying agent lactalbumin, add wall material maltodextrin solution, emulsify 20 after mixing at a high speed~
30min, in 400MPa homogeneous 3 times, spray drying forms.
In such scheme, vitamin premix includes Palimitate-A 495~660ug RE, vitamin described in per 1g
D36.3~8.4ug, 10.728~14.304mg of Vitwas E, 32~46ug of vitamin K1, vitaminB10 .915~
1.22mg, 0.72~0.96mg of vitamin B2,0.875~1.167mg of vitamin B6,1.35~1.95ug of vitamin B12, nicotinic acid
7.2~9.6mg, 126~182ug of folic acid, 2.938~4.243mg of pantothenic acid, 58.5~78mg of vitamin C, biotin 13~
18ug, 180~220mg of choline, 36~44mg of taurine, surplus are vitamin premix carrier.
In such scheme, mineral substance premix described in per 1g includes 59.22~72.38mg of sodium, 77.04~94.16mg of potassium,
90.12~110.147mg of chlorine, 83.533~102.096mg of calcium, 30.557~37.347mg of phosphorus, 12.911~15.781mg of magnesium,
0.9~1.1mg of iron, 0.695~0.849mg of zinc, the μ g of manganese 42~61, the μ g of copper 36~44, the μ g of iodine 7~11, the μ g of selenium 3~4, surplus are
Vitamin premix carrier.
A kind of preparation method of special medicine purposes formula food, comprises the following steps:
(1) each component of the dosage is accurately weighed, in addition to vitamin premix and mineral substance premix;
(2) each component in addition to vitamin premix and mineral substance premix is subjected to mixing 10-15min, made each
Component fully mixes;
(3) material of mixing is put into fluid bed and pelletized;
(4) after the completion of pelletizing, fully mixed according to gradient mode of averaging with vitamin premix and mineral substance premix;
(5) packed after sterilized, detection.
In further technical scheme, granulation conditions are:Use the ethanol water that volume ratio is 55-65%, material temperature
Spend for 45~50 DEG C, EAT is 85~90 DEG C, and wind speed is 650~700rpm, and wriggling revolution speed is 6.71~7.25g/
min。
Pass through above-mentioned technical proposal, the advantages of special medicine purposes formula food provided by the invention and advantageous effects
It is:
1st, the present invention contains marine protein-oyster peptide, is that the currently the only a special medicine purposes containing oyster peptide is matched somebody with somebody
Square food.Oyster peptide extracts from ostreae testa pulverata, more by the small molecule for orienting digestion and the acquisition of specific small peptide isolation technics
Peptide material.The effect of oyster peptide, is a lot, has and promotes neural cell development, increase brain cell acetic acid content of choline, raising immune
Power, improve the important healthcare functions such as middle-aged and old memory.It is both medicinal material that oyster is classified as first by the Ministry of Public Health of China approved
But also as the health care curative effect product of food.
2nd, the product nutrition that the present invention obtains is comprehensive, and each nutrition composition complies fully with special medicine purposes formula food correlation
Standard and Registration regulations etc., and the exploitation of the product can break such product and rely on import, the amount high situation of valency less, profit for a long time
Development and human health in national economy.
3rd, special medicine purposes formula food provided by the invention is pelletized using fluidization, gained after granulation
Product particle is fluffy, and outward appearance and dissolubility are excellent.
4th, preparation technology route of the present invention is ripe, workable, is easy to industrialized production.
Embodiment
The technical scheme in the embodiment of the present invention will be clearly and completely described below.
The invention provides special medicine purposes formula food, specific embodiment are as follows:
Embodiment one:
A kind of special medicine purposes formula food for being applied to 1-10 year crowd, preparation method comprise the following steps:
(1) weigh each component by following parts by weight and (before by all raw material components weight packagings, carry out quality respectively
Detection, it is ensured that every kind of component all reaches quality standards):
Soybean protein isolate:8 parts;
Lactalbumin:5.3 part;
Oyster peptide:0.7 part;
Plant fat powder:32 parts;
Maltodextrin:31 parts;
Isomalt:13 parts;
FOS:2 parts;
Inulin:2 parts;
(2) above-mentioned raw materials are inserted into automatic mixing machine, mixes 15min, obtain a homogeneous mixture;
(3) homogeneous mixture is inserted into fluid bed to be pelletized, granulation conditions are:Use the ethanol water that volume ratio is 65%
Solution, temperature of charge are 45 DEG C, and EAT is 90 DEG C, wind speed 700rpm, wriggling revolution speed 6.8g/min;
(4) it is fully mixed according to gradient mode of averaging with 1 part of vitamin premix and 5 parts of mineral substance premixes after the completion of pelletizing
It is even;
(5) packed after sterilized, detection.
Embodiment two:
A kind of special medicine purposes formula food for being applied to more than 10 years old crowd, preparation method comprise the following steps:
(1) each component is weighed as following weight percent (before by all raw material components weight packagings, carries out matter respectively
Amount detection, it is ensured that every kind of component all reaches quality standards):
Soybean protein isolate:9 parts;
Lactalbumin:5.3 part;
Oyster peptide:0.7 part;
Plant fat powder:26 parts;
Maltodextrin:33.5 parts;
Isomalt:14.5 parts;
FOS:2 parts;
Inulin:2 parts;
(2) above-mentioned raw materials are inserted into automatic mixing machine, mixes 10min, obtain a homogeneous mixture;
(3) homogeneous mixture is inserted into fluid bed to be pelletized, granulation conditions are:Use the ethanol water that volume ratio is 60%
Solution, temperature of charge are 50 DEG C, and EAT is 85 DEG C, wind speed 680rpm, wriggling revolution speed 7g/min;
(4) it is fully mixed according to gradient mode of averaging with 1 part of vitamin premix and 6 parts of mineral substance premixes after the completion of pelletizing
It is even;
(5) packed after sterilized, detection.
According to《Special medicine purposes formula food general rule》(GB 29922-2013) requirement detects to product, detects
As a result it is as follows:
The nutritional ingredient of the formula food of the embodiment of the present invention of table 1
It is comprehensive that the obtained formula food nutrition of the present invention can be seen that by the testing result of table 1, wherein the egg of embodiment one
White matter energy supply ratio accounts for 12.25%, and fatty energy supply ratio accounts for 31.98%, and carbohydrate energy supply ratio accounts for 55.77%.Embodiment two
Protein energy supply ratio accounts for 13.65%, and fatty energy supply ratio accounts for 26.91%, and carbohydrate energy supply ratio accounts for 59.44%.
Vitamin and mineral types and content (100g) in the formula food of 2 embodiment of the present invention of table one
Vitamin and mineral types and content (100g) in the formula food of 3 embodiment of the present invention of table two
The content of beary metal of the inventive formulation food of table 4
Product | Inorganic arsenic mg/kg | Lead mg/kg | Mercury mg/kg | Cadmium mg/kg |
Embodiment one | 0.032 | 0.049 | 0.0040 | 0.0060 |
Embodiment two | 0.039 | 0.048 | 0.0039 | 0.0070 |
Standard | 0.1 | 0.15 | 0.02 | 0.1 |
The foregoing description of the disclosed embodiments, professional and technical personnel in the field are enable to realize or using the present invention.
A variety of modifications to these embodiments will be apparent for those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, it is of the invention
The embodiments shown herein is not intended to be limited to, and is to fit to and principles disclosed herein and features of novelty phase one
The most wide scope caused.
Claims (9)
1. application of the oyster peptide in special medicine purposes formula food is prepared.
2. a kind of special medicine purposes formula food, it is characterised in that including following components:Soybean protein isolate, lactalbumin,
Oyster peptide, plant fat powder, maltodextrin, isomalt, FOS, inulin, vitamin premix and mineral matter are pre-
Batch mixing.
3. a kind of special medicine purposes formula food according to claim 2, it is characterised in that the formula food is applied to
1-10 year crowd, including following components in parts by weight:Soybean protein isolate:0~15 part;Lactalbumin:0~15 part;It is male
Oyster peptide:0~7 part;Plant fat powder:30~36 parts;Maltodextrin:0~66 part;Isomalt:0~20 part;Oligomeric fruit
Sugar:0~4 part;Inulin:0~4 part;Vitamin premix:0~2 part;Mineral substance premix:0~10 part.
4. a kind of special medicine purposes formula food according to claim 2, it is characterised in that the formula food is applied to
More than 10 years old crowds, including following components in parts by weight:Soybean protein isolate:0~17 part;Lactalbumin:0~17 part;
Oyster peptide:0~8 part;Plant fat powder:20~30 parts;Maltodextrin:0~70 part;Isomalt:0~23 part;It is oligomeric
Fructose:0~4 part;Inulin:0~4 part;Vitamin premix:0~2 part;Mineral substance premix:0~12 part.
5. special medicine purposes formula food according to claim 2, it is characterised in that the preparation of the plant fat powder
Method is:Corn oil and linseed oil are according to 4.4~7.0:1 ratio mixes, and after being stirred and evenly mixed with emulsifying agent lactalbumin, adds
Add wall material maltodextrin solution, emulsify 20~30min after mixing at a high speed, in 400MPa homogeneous 3 times, spray drying forms.
6. special medicine purposes formula food according to claim 2, it is characterised in that vitamin premix described in per 1g
Comprising Palimitate-A 495~660ug RE, 6.3~8.4ug of vitamine D3, Vitwas E 10.728~
14.304mg, 32~46ug of vitamin K1, vitaminB10 .915~1.22mg, 0.72~0.96mg of vitamin B2, vitamin
B60.875~1.167mg, 1.35~1.95ug of vitamin B12,7.2~9.6mg of nicotinic acid, 126~182ug of folic acid, pantothenic acid
2.938~4.243mg, 58.5~78mg of vitamin C, 13~18ug of biotin, 180~220mg of choline, taurine 36~
44mg, surplus are vitamin premix carrier.
7. special medicine purposes formula food according to claim 2, it is characterised in that mineral substance premix described in per 1g
Comprising 59.22~72.38mg of sodium, 77.04~94.16mg of potassium, 90.12~110.147mg of chlorine, 83.533~102.096mg of calcium,
30.557~37.347mg of phosphorus, 12.911~15.781mg of magnesium, 0.9~1.1mg of iron, 0.695~0.849mg of zinc, the μ of manganese 42~61
G, the μ g of copper 36~44, the μ g of iodine 7~11, the μ g of selenium 3~4, surplus are vitamin premix carrier.
8. a kind of preparation method of special medicine purposes formula food as claimed in claim 2, it is characterised in that including as follows
Step:
(1) each component of the dosage is accurately weighed, in addition to vitamin premix and mineral substance premix;
(2) each component in addition to vitamin premix and mineral substance premix is subjected to mixing 10-15min, makes each component
Fully mix;
(3) material of mixing is put into fluid bed and pelletized;
(4) after the completion of pelletizing, fully mixed according to gradient mode of averaging with vitamin premix and mineral substance premix;
(5) packed after sterilized, detection.
9. the preparation method of special medicine purposes formula food according to claim 8, it is characterised in that granulation conditions
For:Using the ethanol water that volume ratio is 55-65%, temperature of charge is 45~50 DEG C, and EAT is 85~90 DEG C, wind speed
For 650~700rpm, wriggling revolution speed is 6.71~7.25g/min.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104082739A (en) * | 2014-06-24 | 2014-10-08 | 广州纽健生物科技有限公司 | Comprehensive nutritional and semi-digested formulated food for special medical use, and preparation method thereof |
CN105614898A (en) * | 2016-01-28 | 2016-06-01 | 青岛海洋生物医药研究院股份有限公司 | Marine compound protein powder containing oyster peptide and preparation method of marine compound protein powder containing oyster peptide |
CN106579345A (en) * | 2016-12-21 | 2017-04-26 | 青岛琛蓝海洋生物工程有限公司 | Total nutrient formula containing marine active substances for FSMP (foods for special medical purpose) and preparation method of total nutrient formula |
-
2017
- 2017-09-21 CN CN201710856835.0A patent/CN107692238A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104082739A (en) * | 2014-06-24 | 2014-10-08 | 广州纽健生物科技有限公司 | Comprehensive nutritional and semi-digested formulated food for special medical use, and preparation method thereof |
CN105614898A (en) * | 2016-01-28 | 2016-06-01 | 青岛海洋生物医药研究院股份有限公司 | Marine compound protein powder containing oyster peptide and preparation method of marine compound protein powder containing oyster peptide |
CN106579345A (en) * | 2016-12-21 | 2017-04-26 | 青岛琛蓝海洋生物工程有限公司 | Total nutrient formula containing marine active substances for FSMP (foods for special medical purpose) and preparation method of total nutrient formula |
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