CN107669798A - A kind of composition for treating cold rheumatoid joint pain - Google Patents
A kind of composition for treating cold rheumatoid joint pain Download PDFInfo
- Publication number
- CN107669798A CN107669798A CN201711028726.6A CN201711028726A CN107669798A CN 107669798 A CN107669798 A CN 107669798A CN 201711028726 A CN201711028726 A CN 201711028726A CN 107669798 A CN107669798 A CN 107669798A
- Authority
- CN
- China
- Prior art keywords
- composition
- joint pain
- raw material
- rheumatoid joint
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to drug preparation technique field, more particularly to a kind of composition for treating cold rheumatoid joint pain；Including following raw material by weight：Balsamine 12~18, pyrola 10~20, Ramulus euonymi 10~20, Chinese trumpet creeper 12~18, reticulate millettia 10~20, myrrh 3~8, Chinese prickly ash 8~12, Flos Albiziae 15~25, oyster 10~20, hundred solve rattan 15~25, tingia grass 8~12, Stephania epigaea 3~8, hypericum japonicum 10~20, caulis piperis futokadsurae 8~12；The composition of the present invention, its therapeutic effect is notable, and clinical improvement rate is more than 87%, the pain brought using doctor trained in Western medicine and physiotherapy to patient is avoided simultaneously, is had no side effect after treatment, it is uneasy to recur, and Chinese medicine material easy to operate while selected is readily available, and it is cheap.
Description
Technical field
The present invention relates to drug preparation technique field, more particularly to a kind of composition for treating cold rheumatoid joint pain.
Background technology
Cold rheumatoid joint pain (abbreviation wind close pain) refers to caused muscle after human feeling's wind-cold damp pathogen, arthralgia
For the disease mainly showed.Its clinical characters is to meet cold or Changes in weather then aggravation, and clinical manifestation is more based on pain,
Local most of the inflammation performance, laboratory examination erythrocyte sedimentation rate without red and swollen heat of affected joints is normal, and anti-chain " O " and rheumatoid factor are equal
For feminine gender, therefore this disease is different from rheumatic arthritis and rheumatoid arthritis.According to this sick occurrence regularity and clinical characters, recognize
It is the cause of disease to form wind pass pain for wind-cold damp pathogen, it should be an independence disease.Therefore CAIM's rheumatism
This disease was named as the cold pass of rheumatism by class disease Professional Committee director, famous rheumatism expert Wang Zhaoming researcher in 1974
Section pain.By the clinical observation over 20 years, most scholars think that this name is more definite, are clinically easy to and rheumatic
The diseases such as arthritis, rheumatoid arthritis, ankylosing spondylitis are differentiated there is its practical value, clinical more and more
Doctor uses, and quite has directive significance to clinic.
At present, doctor trained in Western medicine is for the sick treatment medicine that uses more based on antibiotic, hormone, anodyne, and physiotherapy is with office
Portion's insulation, physiotherapy, acupuncture, massage, though so contributing to recover rapidly, slow down pain, its short run effect is fine, can not remove
Root.Drug therapy is carried out for the more long patient of stadium, but prolonged administration of drugs can not only develop immunity to drugs, and can also produce
The adverse reactions such as gastrointestinal function damage, osteoporosis, endocrine disturbance, nervous system disorders and cortin hyperfunction,
And root can not be thoroughly removed, and use physiotherapy, then need to adhere to for a long time, it is impossible to interrupt, but be not easy to effect a radical cure, and due to middle medical treatment
Method has Small side effects, and anti-recurrence rate effect is good, can stablize the state of an illness, indiffusible feature so that it is in cold rheumatoid joint pain
Field has obtained quick application and popularization, and still, because the traditional Chinese medical science of the prior art formula is unreasonable, material composition is not proper
When causing that the therapeutic effect of current rheumatoid arthrosis disease is not notable, and cure rate is relatively low.
There is the Chinese medicine preparation of research treatment cold rheumatoid joint pain the country at present, and achieves certain effect, such as applies
Number CN201410486455.9 invention《A kind of medicine for treating cold rheumatoid joint pain》Disclosing one kind, to treat rheumatism cold
Arthralgic medicine, the raw material matched by following weight are made：Levisticum 8-12 parts, Ramulus Taxilli 8-12 parts, dipsacus root 8-12 parts, Psoralen
Fat 9-15 parts, root of Chinese clematis 8-12 parts, root of bidentate achyranthes 8-12 parts, Herba Lycopi 8-12 parts, safflower 4-8 parts, tag 4-8 parts, due to prior art
In the traditional Chinese medical science formula it is unreasonable, material composition is incorrect, causes the therapeutic effect of current cold rheumatoid joint pain disease not notable,
Cure rate is relatively low and easily recurs.
The content of the invention
The present invention is in order to solve the above technical problems, provide a kind of composition for treating cold rheumatoid joint pain.
Realized particular by following technical scheme：
A kind of composition for treating cold rheumatoid joint pain, including following raw material by weight：Balsamine 12~18,
Pyrola 10~20, Ramulus euonymi 10~20, Chinese trumpet creeper 12~18, reticulate millettia 10~20, myrrh 3~8, Chinese prickly ash 8~12, Flos Albiziae
15~25, oyster 10~20, hundred solve rattan 15~25, tingia grass 8~12, Stephania epigaea 3~8, hypericum japonicum 10~20, caulis piperis futokadsurae 8~
12。
Including following raw material by weight：Balsamine 15, pyrola 15, Ramulus euonymi 15, Chinese trumpet creeper 15, reticulate millettia
15th, myrrh 5, Chinese prickly ash 10, Flos Albiziae 20, oyster 15, hundred solve rattan 20, tingia grass 10, Stephania epigaea 5, hypericum japonicum 15, caulis piperis futokadsurae 10.
Described composition, for agent of steeping in wine, oral solutions, tablet, pill, capsule or lotion.
Described described agent of steeping in wine, it is after raw material is cleaned, the white wine for being 50%vol with alcoholic strength seals immersion,
Summer at least soaks 15d, at least soaks 30d in the winter time.
Described oral solutions, it is after raw material is weighed, cleans, crush, add the water of 3~4 times of the crushed material quality,
Infusion 30min is heated, adds the ethanol of 10 times of amounts of crushed material quality, it is quiet after supersound process 10min under 50KHz frequency
1~2h is put, ethanol is reclaimed, heels is filtered, obtains filtrate, then filter residue repetition is added into water infusion twice, each 30min, by three
Secondary filtrate mixing, which is concentrated into, mixes the 1/2 of filtrate volume, and the sugar content for adjusting concentrate is 20%, packaging.
Described tablet, it is after raw material is weighed, cleans, dries pulverizing, adds water to cook into the medicinal extract that water content is 20%,
20% amylum pregelatinisatum of medicinal extract quality is added, then is infiltrated with 75% ethanol, 0.5% magnesium stearate for adding total amount mixes
It is even, it is tabletted by tablet press machine, obtain tablet.
Described pill, it is to weigh raw material, cleans, crush, adds the ethanol of 5 times of amounts of crushed material quality,
Be ultrasonically treated 15min under 50KHz frequency, stand 2h, reclaim ethanol, by residue drying and crushing, add total amount 20% it is pre-
Gelling starch, then infiltrated with 75% ethanol, it is granulated by comminutor, particle is made, is sieved, obtain pill.
Described capsule, it is to weigh raw material, cleans, dries pulverizing, adds the second of 5 times of amounts of crushed material quality
Alcohol, 20min is ultrasonically treated under 40KHz frequency, stands 2h, reclaimed ethanol, by residue drying and crushing, then use methylcellulose
Or capsulae vacuus prepared by alginates or polyvinyl alcohol or metagelatin is wrapped up, and is prepared into capsule.
Described lotion, it is after raw material is weighed, cleans, dries pulverizing, add 2~3 times of the crushed material quality
Water, infusion 40min is heated, the ethanol of 5 times of amounts of crushed material quality is added, after being ultrasonically treated 15min under 40KHz frequency
1~2h is stood, ethanol is reclaimed, heels is filtered, obtains filtrate, is being concentrated into the 1/2 of filtrate volume, is by concentrate, concentration
20% alcohol presses 1:0.1 mass ratio is mixed to prepare.
In summary, the beneficial effects of the present invention are：The preparation of the present invention is promoting blood circulation and removing blood stasis by with clearing heat and detoxicating,
Wind-damp dispelling, detumescence, the medicine of analgesic efficacy are combined so that composition has the hair for the frequency for mitigating cold rheumatoid joint pain
It is raw, and with channels and collaterals, blood circulation is promoted, effect promoting blood circulation and removing blood stasis, reach the purpose for treating cold rheumatoid joint pain, this hair
Bright composition, its therapeutic effect is notable, and clinical improvement rate is avoided using doctor trained in Western medicine and physiotherapy to patient more than 87%
The pain brought, having no side effect after treatment, Chinese medicine material uneasy to recur and easy to operate while selected is readily available,
It is and cheap.
Embodiment
The embodiment of the present invention is described in further detail below, but the invention is not limited in these realities
Mode is applied, any improvement or replacement on the present embodiment essence spirit, it is claimed to still fall within the claims in the present invention
Scope.
Embodiment 1
A kind of composition for treating cold rheumatoid joint pain, including following raw material by weight：Balsamine 12kg, deer
Hold in the mouth careless 10kg, Ramulus euonymi 10kg, Chinese trumpet creeper 12kg, reticulate millettia 10kg, myrrh 3kg, Chinese prickly ash 8kg, Flos Albiziae 15kg, oyster
10kg, hundred solution rattan 15kg, tingia grass 8kg, Stephania epigaea 3kg, hypericum japonicum 10kg, caulis piperis futokadsurae 8kg.
Described described agent of steeping in wine, it is after raw material is cleaned, the white wine for being 50%vol with alcoholic strength seals immersion,
Summer at least soaks 15d, at least soaks 30d in the winter time.
Application method：The daily morning and evening takes once respectively, every time 30~40ml.
Embodiment 2
A kind of composition for treating cold rheumatoid joint pain, including following raw material by weight：Balsamine 18kg, deer
Hold in the mouth careless 20kg, Ramulus euonymi 20kg, Chinese trumpet creeper 18kg, reticulate millettia 20kg, myrrh 8kg, Chinese prickly ash 12kg, Flos Albiziae 25kg, oyster
20kg, hundred solution rattan 25kg, tingia grass 12kg, Stephania epigaea 8kg, hypericum japonicum 20kg, caulis piperis futokadsurae 12kg.
Described oral solutions, it is after raw material is weighed, cleans, crush, add the water of 3~4 times of the crushed material quality,
Infusion 30min is heated, adds the ethanol of 10 times of amounts of crushed material quality, it is quiet after supersound process 10min under 50KHz frequency
1~2h is put, ethanol is reclaimed, heels is filtered, obtains filtrate, then filter residue repetition is added into water infusion twice, each 30min, by three
Secondary filtrate mixing, which is concentrated into, mixes the 1/2 of filtrate volume, and the sugar content for adjusting concentrate is 20%, packaging.
Application method：Take respectively once in the morning, afternoon and evening daily, every time 50~60ml.
Embodiment 3
A kind of composition for treating cold rheumatoid joint pain, including following raw material by weight：Balsamine 15kg, deer
Hold in the mouth careless 15kg, Ramulus euonymi 15kg, Chinese trumpet creeper 15kg, reticulate millettia 15kg, myrrh 5kg, Chinese prickly ash 10kg, Flos Albiziae 20kg, oyster
15kg, hundred solution rattan 20kg, tingia grass 10kg, Stephania epigaea 5kg, hypericum japonicum 15kg, caulis piperis futokadsurae 10kg.
Described tablet, it is after raw material is weighed, cleans, dries pulverizing, adds water to cook into the medicinal extract that water content is 20%,
20% amylum pregelatinisatum of medicinal extract quality is added, then is infiltrated with 75% ethanol, 0.5% magnesium stearate for adding total amount mixes
It is even, it is tabletted by tablet press machine, obtain tablet.
Application method：Take respectively once in the morning, afternoon and evening daily, 1~2 every time.
Embodiment 4
A kind of composition for treating cold rheumatoid joint pain, including following raw material by weight：Balsamine 12kg, deer
Hold in the mouth careless 20kg, Ramulus euonymi 10kg, Chinese trumpet creeper 18kg, reticulate millettia 10kg, myrrh 8kg, Chinese prickly ash 8kg, Flos Albiziae 25kg, oyster
10kg, hundred solution rattan 25kg, tingia grass 8kg, Stephania epigaea 8kg, hypericum japonicum 10kg, caulis piperis futokadsurae 12kg.
Described pill, it is to weigh raw material, cleans, crush, adds the ethanol of 5 times of amounts of crushed material quality,
Be ultrasonically treated 15min under 50KHz frequency, stand 2h, reclaim ethanol, by residue drying and crushing, add total amount 20% it is pre-
Gelling starch, then infiltrated with 75% ethanol, it is granulated by comminutor, particle is made, is sieved, obtain pill.
Application method：Take respectively once in the morning, afternoon and evening daily, 1~2 every time.
Embodiment 5
A kind of composition for treating cold rheumatoid joint pain, including following raw material by weight：Balsamine 18kg, deer
Hold in the mouth careless 10kg, Ramulus euonymi 20kg, Chinese trumpet creeper 12kg, reticulate millettia 20kg, myrrh 3kg, Chinese prickly ash 12kg, Flos Albiziae 15kg, oyster
20kg, hundred solution rattan 15kg, tingia grass 12kg, Stephania epigaea 3kg, hypericum japonicum 20kg, caulis piperis futokadsurae 8kg.
Described capsule, it is to weigh raw material, cleans, dries pulverizing, adds the second of 5 times of amounts of crushed material quality
Alcohol, 20min is ultrasonically treated under 40KHz frequency, stands 2h, reclaimed ethanol, by residue drying and crushing, then use methylcellulose
Or capsulae vacuus prepared by alginates or polyvinyl alcohol or metagelatin is wrapped up, and is prepared into capsule.
Application method：Take respectively once in the morning, afternoon and evening daily, 1~2 every time.
Embodiment 6
A kind of composition for treating cold rheumatoid joint pain, including following raw material by weight：Balsamine 12kg, deer
Hold in the mouth careless 15kg, Ramulus euonymi 10kg, Chinese trumpet creeper 15kg, reticulate millettia 20kg, myrrh 5kg, Chinese prickly ash 8kg, Flos Albiziae 25kg, oyster
10kg, hundred solution rattan 20kg, tingia grass 12kg, Stephania epigaea 3kg, hypericum japonicum 15kg, caulis piperis futokadsurae 8kg.
Described lotion, it is after raw material is weighed, cleans, dries pulverizing, add 2~3 times of the crushed material quality
Water, infusion 40min is heated, the ethanol of 5 times of amounts of crushed material quality is added, after being ultrasonically treated 15min under 40KHz frequency
1~2h is stood, ethanol is reclaimed, heels is filtered, obtains filtrate, is being concentrated into the 1/2 of filtrate volume, is by concentrate, concentration
20% alcohol presses 1:0.1 mass ratio is mixed to prepare.
Application method, it is to be blent obtained lotion through natural cooling or addition cold wash liquor, regulation temperature is
38 DEG C, allow patient to be immersed in 40min in lotion, patient can not dry after bath, allow with decoction and sweat spontaneously dry.
Experimental example
1st, it is some to randomly select the patient of the cold rheumatoid joint pain disease of similar symptom, is randomly divided into 6 groups, is respectively adopted
Composition prepared by embodiment 1~6 is treated, and the applicant tracks follow-up, counts treatment of the patient to medicine, as a result
As shown in table 1：
Table 1
| Project | Improvement rate % |
| Embodiment 1 | 88.5 |
| Embodiment 2 | 88.1 |
| Embodiment 3 | 87.8 |
| Embodiment 4 | 87.6 |
| Embodiment 5 | 87.7 |
| Embodiment 6 | 88.3 |
2nd, efficacy test example：The present invention takes safety, easy to operate, evident in efficacy, efficient high, and is clinical data institute
Prove, the relevant clinical data of the present invention is as follows：
1st, Song：28 years old, man, made a definite diagnosis in November, 2015 with cold rheumatoid joint pain, using the treatment side of doctor trained in Western medicine
Formula, half a year is continue for, do not improved, after using a course for the treatment of by top, pain is reduced, after continuing taking the two courses, nothing
Sensation of pain, no rebound phenomenon, each course for the treatment of one month.
2nd, Liu：30 years old, man, make a definite diagnosis in May, 2016 with cold rheumatoid joint pain, using the therapeutic modality of doctor trained in Western medicine,
1 year is continue for, during which recurrent exerbation, after using two courses for the treatment of by top, pain is reduced, after continuing taking the two courses, nothing
Sensation of pain, no rebound phenomenon.
So far, patient body is healthy always for the present inventor's follow-up, and the incidence of disease persistently reduces, wherein, improvement rate up to 85% with
On, no rebound phenomenon.
Claims (9)
1. a kind of composition for treating cold rheumatoid joint pain, it is characterised in that including following raw material by weight：Phoenix is celestial
Spend 12~18, pyrola 10~20, Ramulus euonymi 10~20, Chinese trumpet creeper 12~18, reticulate millettia 10~20, myrrh 3~8, Chinese prickly ash 8~
12nd, Flos Albiziae 15~25, oyster 10~20, hundred solve rattan 15~25, tingia grass 8~12, Stephania epigaea 3~8, hypericum japonicum 10~20,
Caulis piperis futokadsurae 8~12.
2. as claimed in claim 1 treatment cold rheumatoid joint pain composition, it is characterised in that including it is following by weight
The raw material of meter：Balsamine 15, pyrola 15, Ramulus euonymi 15, Chinese trumpet creeper 15, reticulate millettia 15, myrrh 5, Chinese prickly ash 10, Flos Albiziae 20,
Oyster 15, hundred solves rattan 20, tingia grass 10, Stephania epigaea 5, hypericum japonicum 15, caulis piperis futokadsurae 10.
3. the composition for the treatment of cold rheumatoid joint pain as claimed in claim 1, it is characterised in that described composition, be
Steep in wine agent, oral solutions, tablet, pill, capsule or lotion.
4. the composition for the treatment of cold rheumatoid joint pain as claimed in claim 3, it is characterised in that described described to steep in wine
Agent, it is after raw material is cleaned, the white wine for being 50%vol with alcoholic strength seals immersion, 15d is at least soaked in summer, in the winter time extremely
30d is soaked less.
5. the composition for the treatment of cold rheumatoid joint pain as claimed in claim 3, it is characterised in that described oral solutions,
It is to clean after raw material is weighed, crushes, add the water of 3~4 times of the crushed material quality, heat infusion 30min, described in addition
The ethanol of 10 times of amounts of crushed material quality, 1~2h is stood after 10min is ultrasonically treated under 50KHz frequency, reclaims ethanol, will be residual
Clout is filtered, and obtains filtrate, then filter residue repetition is added into water infusion twice, each 30min, filtrate mixing will be concentrated into mixing filter three times
The 1/2 of liquid product, the sugar content for adjusting concentrate are 20%, packaging.
6. as claimed in claim 3 treatment cold rheumatoid joint pain composition, it is characterised in that described tablet, be by
After raw material weighs, clean, dries pulverizing, add water to cook into water content be 20% medicinal extract, add medicinal extract quality 20% can
Pressure property starch, then infiltrated with 75% ethanol, 0.5% magnesium stearate for adding total amount mixes, tabletted by tablet press machine,
Obtain tablet.
7. as claimed in claim 3 treatment cold rheumatoid joint pain composition, it is characterised in that described pill, be by
Raw material weighs, and cleans, and crushes, and adds the ethanol of 5 times of amounts of crushed material quality, is ultrasonically treated under 50KHz frequency
15min, stand 2h, reclaim ethanol, by residue drying and crushing, add 20% pregelatinized starch of total amount, then with 75% second
Alcohol infiltrates, and is granulated by comminutor, particle is made, and sieves, obtains pill.
8. the composition for the treatment of cold rheumatoid joint pain as claimed in claim 3, it is characterised in that described capsule, be
Raw material is weighed, cleaned, dries pulverizing, the ethanol of 5 times of amounts of crushed material quality is added, under 40KHz frequency at ultrasound
Manage 20min, stand 2h, reclaim ethanol, by residue drying and crushing, then with methylcellulose or alginates or polyvinyl alcohol or
Capsulae vacuus prepared by metagelatin is wrapped up, and is prepared into capsule.
9. the composition for the treatment of cold rheumatoid joint pain as claimed in claim 3, it is characterised in that described lotion, be
After raw material is weighed, clean, dries pulverizing, add the water of 2~3 times of the crushed material quality, heat infusion 40min, add institute
The ethanol of 5 times of amounts of crushed material quality is stated, 1~2h is stood after 15min is ultrasonically treated under 40KHz frequency, reclaims ethanol, will be residual
Clout is filtered, and obtains filtrate, is being concentrated into the 1/2 of filtrate volume, and concentrate, the alcohol that concentration is 20% are pressed into 1:0.1 quality
Than being mixed to prepare.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711028726.6A CN107669798A (en) | 2017-10-29 | 2017-10-29 | A kind of composition for treating cold rheumatoid joint pain |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711028726.6A CN107669798A (en) | 2017-10-29 | 2017-10-29 | A kind of composition for treating cold rheumatoid joint pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107669798A true CN107669798A (en) | 2018-02-09 |
Family
ID=61141979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711028726.6A Pending CN107669798A (en) | 2017-10-29 | 2017-10-29 | A kind of composition for treating cold rheumatoid joint pain |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107669798A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058673A (en) * | 2010-12-15 | 2011-05-18 | 湖南九典制药有限公司 | Chinese medicine composition for expelling wind and removing dampness and preparation method thereof |
| CN106266046A (en) * | 2016-11-11 | 2017-01-04 | 东莞市百替生物科技有限公司 | A kind of Chinese medicine composition treating cold rheumatoid joint pain and preparation method |
-
2017
- 2017-10-29 CN CN201711028726.6A patent/CN107669798A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058673A (en) * | 2010-12-15 | 2011-05-18 | 湖南九典制药有限公司 | Chinese medicine composition for expelling wind and removing dampness and preparation method thereof |
| CN106266046A (en) * | 2016-11-11 | 2017-01-04 | 东莞市百替生物科技有限公司 | A kind of Chinese medicine composition treating cold rheumatoid joint pain and preparation method |
Non-Patent Citations (1)
| Title |
|---|
| XU Y: "Treatment with SiMiaoFang, an anti-arthritis chinese herbal formula, inhibits cartilage matrix degradation in osteoarthritis rat model.", 《REJUVENATION RESEARCH》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104367911A (en) | Traditional Chinese medicinal composition for treating rheumatic arthritis and rheumatoid arthritis and preparation method thereof | |
| CN101554430B (en) | Medicinal liquor for treating rheumatic sciatica | |
| CN103393840A (en) | Traditional Chinese medicine composition for treating osteoarthritis | |
| CN103479837B (en) | External medicine for curing hyperosteogeny and preparation method thereof | |
| CN102949680B (en) | Medicinal liquor for treating cervical spondylosis and preparation method thereof | |
| CN101095933B (en) | Chinese traditional medicine compound recipe for healing bones and treating wound | |
| CN104173546A (en) | Traditional Chinese medicine liquid for treating rhinitis | |
| CN101002848B (en) | Medicine for treating recurrent uarthritis, and its preparing method | |
| CN101002873A (en) | Medicine for treating recurrent gout, and its preparing method | |
| CN103977367A (en) | Traditional Chinese medicament for treating qi-stagnation blood-aggregation type bedsore and preparation method thereof | |
| CN101708292B (en) | Chinese medicament for treating rheumatic and rheumatoid diseases | |
| CN102949507B (en) | Traditional Chinese medicine lotion for treating lumbocrural pain and preparation method thereof | |
| CN107669798A (en) | A kind of composition for treating cold rheumatoid joint pain | |
| CN102283973B (en) | Traditional Chinese medicine plaster for treating benign tumor and reducing weight and preparation method thereof | |
| CN105311210A (en) | Pharmaceutical composition for treating rheumatoid bone diseases | |
| CN103566241A (en) | Traditional Chinese medicinal composition for treating diarrhea | |
| CN104173932A (en) | Traditional Chinese medicine composition for treating cervical spondylosis | |
| CN103285108B (en) | Chinese medicinal composition treating lumbago | |
| CN106361840A (en) | Traditional Chinese medicine composite used for treating rheumatism and preparing method thereof | |
| CN103623085B (en) | Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof | |
| CN106853193A (en) | It is a kind of to treat Chinese medicine of rheumatoid arthritis and preparation method thereof | |
| CN105213666A (en) | Two black Lignum Pini Nodi Chinese medicinal liquor | |
| CN1171967A (en) | Medicinal liquid Yuyepizhengke for curing rheumatic arthritis | |
| CN105663850A (en) | Traditional Chinese medicine composition for treating oral ulcer | |
| CN104524077A (en) | Traditional Chinese medicine capsule for treating sciatica and preparation method of traditional Chinese medicine capsule |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180209 |
|
| RJ01 | Rejection of invention patent application after publication |