CN107669564B

CN107669564B - Skin care composition with functions of repairing and regenerating, moisturizing and delaying senescence

Info

Publication number: CN107669564B
Application number: CN201711162611.6A
Authority: CN
Inventors: 江少卿
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-11-21
Filing date: 2017-11-21
Publication date: 2020-10-16
Anticipated expiration: 2037-11-21
Also published as: CN107669564A

Abstract

The invention provides a skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility, which comprises a component A, a component B and a component C; the component A is herba Dendrobii extract, Aloe extract, fructus Citri Sarcodactylis extract, herba Centellae extract, fructus Sechii edulis extract, and herba Selaginellae extract; the component B is oligopeptide; wherein the oligopeptide is selected from one or more of oligopeptide-1, oligopeptide-2, oligopeptide-3, oligopeptide-4, oligopeptide-5, oligopeptide-6, oligopeptide-10, palmitoyl pentapeptide-3, palmitoyl tripeptide-1, palmitoyl tripeptide-5, palmitoyl tetrapeptide-3, myristic pentapeptide-11, acetyl tetrapeptide-5, acetyl pentapeptide-1, acetyl hexapeptide-8 and acetyl dipeptide-1; the component C is cosmetic auxiliary materials and a cosmetic matrix.

Description

Skin care composition with functions of repairing and regenerating, moisturizing and delaying senescence

Technical Field

The invention relates to the technical field of cosmetics, in particular to a skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility.

Background

Due to changes in age and environmental factors of prolonged contact failure, the appearance, physical characteristics and physiological function of the skin change in various ways, the most notable of which include increased fine lines and wrinkles, loss of elasticity, increased sagging, loss of firmness, loss of uniformity of tone, rough surface texture and mottled pigmentation. Less obvious but measurable changes that occur or experience long-term environmental damage as skin aging include a general decrease in cell and tissue viability, a decrease in cell replication rates, a slowing of skin blood flow, a reduction in moisture, an accumulation of structural and functional errors, and a decrease in the ability of the skin to self-reconstitute and repair. Many of the changes in appearance and function described above are due to changes in the outer, epidermal layer of the skin and lack of water in the inner layer, while other changes are due to changes in the dermis. When skin damage occurs, many natural and complex biochemical mechanisms begin to attempt to repair the damage.

In addition, the increase of the working pressure causes the problem that how to care the skin becomes a key concern for the beauty lovers. Facial masks, one category of skin care products. The most basic and important purpose is to make up for the insufficient cleaning work of makeup removal and face washing, and realize other maintenance functions such as water replenishing and moisturizing, whitening, anti-aging, grease balancing and the like by matching with other essential components on the basis.

Although the skin care products on the market are various, the skin care products have different qualities and good effects. Some products containing lead, mercury or hormone cannot play a role in skin care, but seriously threaten skin health; some skin care products contain large water content or weakly alkaline components, and skin edema and allergy phenomena can be caused by excessive infiltration when the skin care products are contacted with the skin for a long time.

Therefore, in order to solve the above problems, the present invention provides a skin care composition with functions of repairing and regenerating, moisturizing and delaying aging, which has the functions of strongly purifying the skin, nourishing and moistening, activating the skin, activating skin cells and regeneration, maintaining pore refreshing, accelerating wound healing and tissue repair, fading fine lines, moisturizing and preventing allergy and anti-allergy.

Disclosure of Invention

In order to solve the above problems, the present invention provides in a first aspect a skin care composition having functions of rejuvenation, moisturizing, delaying aging, comprising a component a, a component B, and a component C; the component A is herba Dendrobii extract, Aloe extract, fructus Citri Sarcodactylis extract, herba Centellae extract, fructus Sechii edulis extract, and herba Selaginellae extract; the component B is oligopeptide; wherein the oligopeptide is selected from one or more of oligopeptide-1, oligopeptide-2, oligopeptide-3, oligopeptide-4, oligopeptide-5, oligopeptide-6, oligopeptide-10, palmitoyl pentapeptide-3, palmitoyl tripeptide-1, palmitoyl tripeptide-5, palmitoyl tetrapeptide-3, myristic pentapeptide-11, acetyl tetrapeptide-5, acetyl pentapeptide-1, acetyl hexapeptide-8 and acetyl dipeptide-1; the component C is cosmetic auxiliary materials and a cosmetic matrix.

In one embodiment, the weight ratio of the dendrobium officinale extract to the aloe extract, the bergamot extract, the centella asiatica extract, the chayote extract and the selaginella tamariscina extract in the a component is (0.2-1): (3-8): (0.3-0.7): (1-3): (0.5-2): (0.3-1).

In one embodiment, the weight ratio of the dendrobium officinale extract to the aloe vera extract, the bergamot extract, the centella asiatica extract, the chayote extract, and the selaginella tamariscina extract in the a fraction is 0.6: 7: 0.5: 1.2: 1.1: 0.7.

in one embodiment, the oligopeptide in the component B is oligopeptide-1, palmitoyl tripeptide-5, acetyl pentapeptide-1.

In one embodiment, the weight ratio of oligopeptide-1 to palmitoyl tripeptide-5, acetyl pentapeptide-1 in the oligopeptide is 1: (0.5-1.2): (0.2-0.7).

In one embodiment, the sum of the A component and the B component is 2-10% of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility.

In one embodiment, the weight ratio of the a component to the B component is (5-12): 1.

in one embodiment, the cosmetic auxiliary materials in the component C comprise one or more of modified chitosan, surfactant, essence and colorant.

In one embodiment, the skin care composition with the functions of rejuvenation, moisturizing and delaying aging is applied to a mask, an eye cream, a face cream, an essence, a face cleanser, a stock solution, a toner, an emulsion, a cream, a hydrosol, a sun block or a BB cream.

The second aspect of the invention provides a preparation method of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility, which comprises the following steps:

(1) adding the cosmetic adjuvants and cosmetic matrix in the component C into a stirring container, heating to 78-80 deg.C, maintaining for 20min, and cooling to 35-40 deg.C;

(2) adding the dendrobium officinale extract, the aloe extract, the bergamot extract, the centella asiatica extract, the chayote extract and the selaginella tamariscina extract which are used as the component A into the step (1), and stirring for 10-15min to uniformly mix the materials;

(3) adding component B oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1 into the step (2), stirring for 10-15min, filtering, discharging and standing; and packaging and warehousing after the detection is qualified.

The above-described and other features, aspects, and advantages of the present application will become more apparent with reference to the following detailed description.

Detailed Description

The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.

The term "prepared from …" as used herein is synonymous with "comprising". The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.

The conjunction "consisting of …" excludes any unspecified elements, steps or components. If used in a claim, the phrase is intended to claim as closed, meaning that it does not contain materials other than those described, except for the conventional impurities associated therewith. When the phrase "consisting of …" appears in a clause of the subject matter of the claims rather than immediately after the subject matter, it defines only the elements described in the clause; other elements are not excluded from the claims as a whole.

When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.

The singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. "optional" or "any" means that the subsequently described event or events may or may not occur, and that the description includes instances where the event occurs and instances where it does not.

Approximating language, as used herein throughout the specification and claims, is intended to modify a quantity, such that the invention is not limited to the specific quantity, but includes portions that are literally received for modification without substantial change in the basic function to which the invention is related. Accordingly, the use of "about" to modify a numerical value means that the invention is not limited to the precise value. In some instances, the approximating language may correspond to the precision of an instrument for measuring the value. In the present description and claims, range limitations may be combined and/or interchanged, including all sub-ranges contained therein if not otherwise stated.

In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.

"Polymer" means a polymeric compound prepared by polymerizing monomers of the same or different types. The generic term "polymer" embraces the terms "homopolymer", "copolymer", "terpolymer" and "interpolymer".

"interpolymer" means a polymer prepared by polymerizing at least two different monomers. The generic term "interpolymer" includes the term "copolymer" (which is generally used to refer to polymers prepared from two different monomers) and the term "terpolymer" (which is generally used to refer to polymers prepared from three different monomers). "blend" means a polymer formed by two or more polymers being mixed together by physical or chemical means.

In one embodiment, the weight ratio of the dendrobium officinale extract to the aloe extract, the bergamot extract, the centella asiatica extract, the chayote extract and the selaginella tamariscina extract in the a component is (0.2-1): (3-8): (0.3-0.7): (1-3): (0.5-2): (0.3-1); preferably, the weight ratio of the dendrobium officinale extract to the aloe extract, the bergamot extract, the centella asiatica extract, the chayote extract and the selaginella tamariscina extract in the component A is 0.6: 7: 0.5: 1.2: 1.1: 0.7.

dendrobium officinale Kimura et Migo

The Dendrobium officinale is stem of Dendrobium officinale Kimuraet Migo of Orchidaceae. Sweet in flavor and slightly cold in nature. Mainly contains alkaloid, coumarins compounds, polysaccharides compounds, phenanthrenes compounds, bibenzyls compounds, sesquiterpenes compounds and steroidal glycosides compounds. Has effects in promoting salivation, invigorating stomach, nourishing yin, clearing away heat, moistening lung, invigorating kidney, improving eyesight, strengthening waist, enhancing immunity, clearing heat from throat, and resisting tumor.

The extraction method of the dendrobium officinale extract comprises the following steps:

grinding the dendrobium officinale into powder, sieving the powder to obtain a 30-mesh powder material, adding 85% ethanol by mass fraction, uniformly mixing, heating to 70 ℃, performing reflux degreasing for 1.0h, removing residues, drying to obtain a material, uniformly mixing with water, heating to 95 ℃, performing reflux extraction in a water bath for 60min, cooling to room temperature, filtering, removing residues to obtain a material, adding absolute ethanol, uniformly shaking, refrigerating and standing overnight, centrifuging at 4000r/min for 20min, removing a supernatant to obtain a material, finally adding absolute ethanol, washing for 2 times, centrifuging to remove the supernatant to obtain the material, drying the material, and cooling to room temperature to obtain the dendrobium officinale extract.

The dendrobium officinale extract has the effects of good moisturizing effect, fine line fading, lasting moisturizing, damaged skin repairing and the like.

Aloe vera

Aloe is a perennial evergreen herb of liliaceae, and has the following properties and tastes: bitter and cold. Aloe extract has antibacterial, antiinflammatory, skin caring, stomach invigorating, diarrhea relieving, heart tonifying, blood circulation promoting, immunity and regeneration promoting, immunity and anti-tumor, toxic materials clearing away, antiaging, analgesic, tranquilizing, and sunscreen effects.

The extraction method of the aloe extract comprises the following steps:

selecting ripe aloe leaf, cleaning, peeling, performing ultraviolet sterilization for 10 minutes, grinding into slurry, adding antioxidant 4-6 per mill and ethanol 10-15 per mill into the slurry, putting the slurry into a high-speed separator for solid-liquid separation at 4-6 ℃, filtering to obtain solid, adding 10 times of water into the solid, boiling the solid for 60-90 minutes, taking filtrate, mixing the first filtrate with the second filtrate, and concentrating under reduced pressure to dryness to obtain the aloe extract.

Aloe has effects in promoting wound healing, regulating immunity, resisting oxidation, resisting bacteria and virus.

Bergamot

Finger citron (scientific name: Citrus medica l. var. sarcodactylis Swingle) is the fruit of the rutaceae plant finger citron. When the fruit is ripe, the carpel is separated to form a slender and curved fruit flap, which is like a finger, so the fruit is named fingered citron. The fructus Citri Sarcodactylis is also named as folium et cacumen Murrayae, fructus Ponciri Trifoliatae, and fructus Citri Sarcodactylis. The fingered citron is mainly produced in Minyue, Chuan, Jiangzhe and other provinces, wherein Zhejiang Jinhua fingered citron is the most famous and is called the immortal product in fruit, the miracle flower in the world and the elegant gold fingered citron. The functional indications are as follows: soothing liver, regulating qi, harmonizing stomach and relieving pain. Can be used for treating qi stagnation of liver and stomach, distending pain in chest and hypochondrium, fullness and distention in stomach, anorexia, and emesis. The main components are terpenes, sesquiterpenes, higher alcohols, aldehydes, ketones, esters and the like, and the main components have good inhibition effect on main bacteria and gram-positive bacteria causing acne.

The extraction method of the bergamot extract comprises the following steps:

soaking fresh fructus Citri Sarcodactylis in distilled water, heating in water bath for 5-15min at 50-70 deg.C, rinsing with distilled water, and collecting peel; squeezing, and spraying distilled water in the squeezing process, wherein the mass ratio of bergamot peel to the sprayed distilled water is 4:1, so as to obtain squeezed bergamot peel and eluent; filtering to obtain filtrate and filter residue, washing the filter residue to obtain washing liquid, mixing the obtained filtrate and washing liquid, performing centrifugal separation, standing to obtain layering liquid, and collecting an oil phase part in the layering liquid to obtain the bergamot extract.

Centella asiatica

Centella asiatica (L.) Urban, perennial herbs, stoloniferous stems, slender and rooted on the nodes. The Chinese medicinal herbs are named as big-bowl caving, calanthe mollis, Eleocharis Turcz, centella asiatica, cricket shell grass, herba Cedar, eighteen-rhizome, juncus nigra, Eleocharis gigantea, Gelidium japonicum, mouth-collapsing bowl, entropis pheretis, begonia dubia, Eleocharis mollissima, herba asari, chisella chinensis, horseshoe crab caraway, lysimachia christinae Hance, herba erigerontis, boellia diffusa, shepherdspurse herb, goby herb, copper coin breaking, Chinese lobelia, herba Spirodelae, wintergreen, Chinese ladybus herb, herba Spiranthi Praeparata, giant leaf common elsholly leaf, calabash and plum blossom. The functional indications are as follows: clear heat and remove toxicity, induce diuresis to alleviate edema.

The centella asiatica extract can tighten the connecting part of the epidermis and the dermis, can soften the skin, helps to promote the formation of collagen in the dermis and has the effect of tightening the skin. Can also help the injured tissue to heal and compact the skin. Can promote the close connection between the epidermis and the dermis, inhibit the increase of fat cells, and prevent skin edema and obesity.

The extraction method of the centella extract comprises the following steps:

crushing centella asiatica, sieving with a 30-mesh sieve, heating and extracting with 85% ethanol, heating the feed liquid at a mass-volume ratio of 1:50(W/v), heating to 60 ℃, performing ultrasonic-assisted extraction with ultrasonic power of 320W twice for 1.5h each time, mixing the extraction filtrates, performing suction filtration on the extraction filtrate with a diatomite filter cake, introducing the obtained filtrate into macroporous adsorption resin, washing the adsorbed resin with distilled water until the effluent is colorless and transparent, eluting with 3 times of column volume of 85% ethanol, and collecting the eluate; macroporous adsorbent resin type D-101; concentrating the eluate under reduced pressure to 1/6 of original volume, vacuum filtering to remove precipitate to obtain filtrate, ultrafiltering to desalt, with ultrafiltration membrane cut-off molecular weight of 5K dalton and ultrafiltration pressure of 8psi to obtain ultrafiltration cut-off concentrated solution, and freeze drying to obtain herba Centellae extract.

Chayote

The chayote (Sechiamed (Jacq.) Swatz.) is a fruit of perennial climbing herbaceous plants of chayote genus of Cucurbitaceae family, is native to Mexico America, is called Bistor melon, Wannian melon, stick melon and the like, is tender, crisp and juicy, contains much more potassium and zinc than common vegetables, is rich in VB, VC and various trace elements, is a health-care vegetable deeply loved by people, and is an ideal health-care food for zinc-deficient children. Has the effects of regulating qi-flowing, regulating stomach, dispersing stagnated liver qi, and relieving cough, and is suitable for patients with dyspepsia, chest distress, flatulence, emesis, liver and stomach pain, tracheitis, cough, and excessive phlegm. The chayote contains abundant polysaccharides, polyphenols and flavonoids, and the substances have good whitening, anti-aging, anti-oxidation and other effects on human skin, also have good whitening, moisturizing and moisturizing effects on the skin, and can make the skin recover the white, red, moist and full health state after long-term use.

The extraction method of the chayote extract comprises the following steps:

cleaning fructus Sechii edulis, cutting into strips, soaking in distilled water for 0.5 hr, taking out, naturally air drying, freezing, drying in freeze dryer, pulverizing, and sieving with 80 mesh sieve. A certain amount of chayote powder is filled into a 250mL three-neck flask with a condenser tube, the chayote powder is placed into an ultrasonic reactor, the chayote is extracted and concentrated according to the conditions of the ethanol concentration of 69%, the ultrasonic temperature of 71 ℃, the liquid-material ratio of 25mL/g and the ultrasonic time of 30min, and the chayote extract is obtained.

Herba Selaginellae (Thunb.) Selaginella

Dried whole plant of Selaginella tamariscina (Beauv.) Spring) or Selaginella tamariscina Puluinata (hook. et Grev.) in the form of a tropical, white, green, or brown. Is named as juniper, one grab, tiger claw, perennial grass, ten thousand-year pine, Jiu-died Senecio cannabifolius less, and Fallopia multiflora. It is commonly used to treat hemoptysis, hematemesis, hematochezia, rectocele, menorrhagia, metrorrhagia, amenorrhea, rheumatalgia, traumatic injury, traumatic hemorrhage, common cold, epistaxis, metrorrhagia, etc. The herba selaginellae dry powder is applied to the navel belly of the infant to diminish inflammation and stop bleeding, and the effect is good. Herba Selaginellae has skin caring effect. The facial mask is mixed with the roll dry powder and egg white and applied to the face, so that the face is smooth and beautiful. Selaginella tamariscina can be orally administered for strengthening yin and nourishing essence.

The extraction method of the selaginella extract comprises the following steps:

pulverizing dried herba Selaginellae, sieving, reflux-extracting with 60-80 vol% ethanol water solution for 2-3 times, mixing ethanol extractive solutions, filtering, distilling under 0.05-0.1MPa to recover ethanol, and drying at 35-45 deg.C under vacuum degree of 0.05-0.1MPa to constant weight to obtain herba Selaginellae extract.

The selaginella extract contains gelikeina, has super-strong water locking capacity, enhances the moisture retention, elasticity and smoothness of skin, has an antioxidant function and a natural cell activator, has the functions of strongly purifying the muscle bottom, removing free radicals and blackhead grease dirt, activating skin cells and regeneration, maintaining pore refreshing, accelerating wound healing and tissue repair, accelerating the synthesis of an aging collagen precursor, reducing skin redness and resisting erythra.

In one embodiment, the weight ratio of oligopeptide-1 to palmitoyl tripeptide-5, acetyl pentapeptide-1 in the oligopeptide is 1: (0.5-1.2): (0.2-0.7); preferably, the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3.

the oligopeptide complex can remove oxygen radicals that reduce the ability of biomolecules to contribute to the elastic function of the skin and thus prevent the biological oxidation of the skin; the oligopeptides are capable of ameliorating skin wrinkles by increasing collagen synthesis in the skin, thereby resulting in an increase in elastic fibers in the dermis of the skin; the oligopeptide has the effect of inhibiting muscle contraction or muscle relaxation. In particular, the muscle relaxation effect occurs in facial expression muscles used when people make facial expressions such as smiles or frowns, and the oligopeptide complex can reduce the contraction force of the expression muscles.

In one embodiment, the sum of the A component and the B component is 2 to 10 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; preferably, the sum of the A component and the B component is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility.

In one embodiment, the weight ratio of the a component to the B component is (5-12): 1; preferably, the weight ratio of the component A to the component B is 8: 1.

In one embodiment, the modified chitosan in the component C accounts for 5-20% of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; preferably, the modified chitosan in the component C accounts for 11% of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility.

In one embodiment, the surfactant is one or more of lecithin, saponin, alkyl glycoside, anionic surfactant, cationic surfactant, nonionic surfactant, and amphoteric surfactant.

The anionic brightening agents include sodium laurate, sodium stearate, sodium oleate, sodium linolenate, alkyl sulfates, alkylbenzene sulfonic acids such as hexylbenzene sulfonic acid, octylbenzene sulfonic acid, dodecylbenzene sulfonic acid and the like and salts thereof, polyoxyalkylene alkyl ether sulfates, polyoxyalkylene ether sulfates, polyoxyethylene alkyl sulfate ester salts, sulfosuccinic alkyl ester salts, polyoxyalkylene alkylphenyl ether sulfates, alkane sulfonates, octyltrimethylammonium hydroxide, dodecyltrimethylammonium hydroxide, alkyl sulfonates, polyoxyethylene alkylphenyl ether sulfates, polyoxyalkylene alkyl ether acetates, alkyl phosphates, polyoxyalkylene alkyl ether phosphates, acyl glutamates, alpha-acyl sulfonates, alkyl sulfonates, alkylallyl sulfonates, alpha-olefin sulfonates, sodium linolenates, alkyl sulfates, alkyl sulfosuccinates, polyoxyalkylene alkyl ester salts, polyoxyalkylene alkyl ether sulfates, alkyl sulfonates, alkyl sulfates, alkyl, One or more of alkyl naphthalene sulfonate, alkane sulfonate, alkyl or alkenyl sulfate, alkyl amide sulfate, alkyl or alkenyl phosphate, alkyl amide phosphate, alkanoyl alkyl taurate, N-acyl amino acid salt, sulfosuccinate, alkyl ether carboxylate, amide ether carboxylate, alpha-sulfo fatty acid ester salt, alanine derivative, glycine derivative and arginine derivative.

The cationic surfactant includes alkyltrimethyl ammonium chloride, stearyltrimethyl ammonium chloride, lauryltrimethyl ammonium chloride, hexadecyltrimethyl ammonium chloride, tallowalkyltrimethyl ammonium chloride, behenyltrimethyl ammonium chloride, stearyltrimethyl ammonium bromide, behenyltrimethyl ammonium bromide, distearyldimethyl ammonium chloride, dicocoyldimethyl ammonium chloride, dioctyldimethyl ammonium chloride, di (POE) oleylmethyl (2OE) ammonium chloride, benzalkonium chloride, alkylbenzalkonium chloride, alkyldimethyl benzalkonium chloride, benzethonium chloride, stearyldimethyl benzyl ammonium chloride, lanolin derivative quaternary ammonium salt, diethylaminoacetamide stearate, dimethylaminopropionamide stearate, amidopropyldimethylhydroxypropylammonium behenate, stearoylcholinesteramidoformylmethyl pyridinium chloride, cetylpyridinium chloride, and the like, Tall oil alkylbenzylhydroxyethylimidazolinium chloride and benzylammonium salt.

The nonionic surfactant includes polyoxyalkylene ether, polyoxyalkylene alkyl ether, polyoxyalkylene fatty acid ester, polyoxyalkylene fatty acid diester, polyoxyalkylene resin acid ester, polyoxyalkylene (hardened) castor oil, polyoxyalkylene alkylphenol, polyoxyalkylene alkylphenyl ether, polyoxyalkylene phenylphenyl ether, polyoxyalkylene alkyl ester, sorbitan fatty acid ester, polyoxyalkylene sorbitan alkyl ester, polyoxyalkylene sorbitan fatty acid ester, polyoxyalkylene sorbitol fatty acid ester, polyoxyalkylene glycerin fatty acid ester, polyglycerol alkyl ether, polyglycerol fatty acid ester, sucrose fatty acid ester, fatty acid alkanolamide, alkyl glucoside, polyoxyalkylene fatty acid diphenyl ether, polypropylene glycol, diethylene glycol, polyoxyalkylene modified silicone, polyglyceryl modified silicone, glyceryl modified silicone, polyoxyalkylene resin acid ester, sorbitan fatty acid ester, polyoxyalkylene sorbitan fatty acid ester, One or more of a sugar-modified silicone, a fluorine-based surfactant, a polyoxyethylene/polyoxypropylene block copolymer, and an alkylpolyoxyethylene/polyoxypropylene block copolymer ether.

The amphoteric surfactant includes imidazoline type, amide betaine type, alkyl amide betaine type, alkyl sulfobetaine type, amide sulfobetaine type, hydroxy sulfobetaine type, carbon betaine type (carbobetanetype), phosphoric acid betaine type, aminocarboxylic acid type, and amide amino acid type amphoteric surfactants. More specifically, as examples thereof, mention may be made of imidazoline type amphoteric surfactants such as 2-undecyl-N, N- (hydroxyethyl carboxymethyl) -2-imidazolinium sodium, 2-coco-2-imidazolinium hydroxide-1-carboxyethoxy disodium salt; alkyl betaine type amphoteric surfactants such as lauryl dimethyl glycine betaine, myristyl betaine; and amidobetaine-type amphoteric surfactants such as coconut oil fatty acid amide propyl dimethylamino acetic acid betaine, palm kernel oil fatty acid amide propyl dimethylamino acetic acid betaine, tallow fatty acid amide propyl dimethylamino acetic acid betaine, hardened tallow fatty acid amide propyl dimethylamino acetic acid betaine, lauric acid amide propyl dimethylamino acetic acid betaine, myristic acid amide propyl dimethylamino acetic acid betaine, palmitic acid amide propyl dimethylamino acetic acid betaine, stearic acid amide propyl dimethylamino acetic acid betaine, oleic acid amide propyl dimethylamino acetic acid betaine; alkyl sulfobetaine-type amphoteric surfactants such as coconut oil fatty acid dimethyl sulfopropyl betaine; alkyl hydroxy sulfobetaine-type amphoteric surfactants such as lauryl dimethylamino hydroxy sulfobetaine; phosphoric acid betaine type amphoteric surfactants such as lauryl hydroxy phosphoric acid betaine; amphoteric surfactants of the amide amino acid type, such as sodium lauroyl-N ' -hydroxyethyl-N ' -carboxymethylglyoxal, sodium oleoyl-N ' -hydroxyethyl-N ' -carboxymethylglyoxal, sodium cocoyl-N ' -hydroxyethyl-N ' -carboxymethylglyoxal, potassium lauroyl-N ' -hydroxyethyl-N ' -carboxymethylethylenediamine, sodium lauroyl-N ' -hydroxyethyl-N ' -carboxymethylglyoxal, sodium oleoyl-N-hydroxyethyl-N ' -carboxymethylglyoxal, sodium cocoyl-N ' -hydroxyethyl-N ' -carboxymethylglyoxal, N-lauroyl-N-hydroxyethyl-N ', N' -dicarboxymethylethylenediamine monosodium salt, N-oleoyl-N-hydroxyethyl-N ', N' -dicarboxymethylethylenediamine monosodium salt, N-cocoyl-N-hydroxyethyl-N ', N' -dicarboxymethylethylenediamine monosodium salt, N-lauroyl-N-hydroxyethyl-N ', N' -dicarboxymethylethylenediamine disodium salt, N-oleoyl-N-hydroxyethyl-N ', N' -dicarboxymethylethylenediamine disodium salt, N-cocoyl-N-hydroxyethyl-N ', N' -dicarboxymethylethylenediamine disodium salt.

In one embodiment, the essence is one or more of ambergris, castoreum, musk, civet, rose oil, peppermint oil, spearmint oil, lavender oil, fennel oil, tea tree essential oil.

In one embodiment, the colorant is one of capsanthin, sorghum red, and florigen.

The cosmetic matrix of the invention is an oily matrix, a powdery matrix or a solvent.

The oily matrix is one or more of coconut oil, castor oil, olive oil, palm oil, mink oil, snake oil, tallow, lanolin, carnauba wax, spermaceti wax, beeswax, vaseline, liquid paraffin, squalane, and silicone oil.

The powdery matrix is one or more of talcum powder, kaolin, zinc white, titanium dioxide and bentonite.

The solvent is one or more of water, ethanol, isopropanol, butanediol, n-butanol, acetone, butanone, ethyl acetate and butyl acetate.

In one embodiment, the modified chitosan is guanidine chitosan prepared by catalytic reaction of N-methyl guanidino acetic acid (CAS: 6020-87-7) as a raw material, and then grafted with 2, 3-epoxypropyltrimethyl ammonium chloride.

The preparation method of the modified chitosan comprises the following steps:

(1) guanidyl chitosan: adding chitosan and 2-morpholine ethanesulfonic acid/hydrochloric acid buffer solution (2-morpholine ethanesulfonic acid concentration 25mmol/L, pH 5), stirring to dissolve, adding coupling agent EDC (1-ethyl- (3-dimethylaminopropyl) carbodiimide hydrochloride) and NHS (N-hydroxysuccinimide), and stirring for 0.5 h; adding N-methyl guanidinoacetic acid, continuously reacting for 12h under the condition of stirring at room temperature, adding a small amount of hydroxylamine hydrochloride to terminate the reaction, adjusting the pH to 9 by using a standard sodium hydroxide solution to obtain a guanidino chitosan product, filling the product into a dialysis bag with the molecular weight cutoff of 8000, dialyzing for one week by using distilled water, and freeze-drying to obtain the guanidino chitosan; the weight ratio of the chitosan to the 2-morpholine ethanesulfonic acid/hydrochloric acid buffer solution, the coupling agents EDC and NHS is 1: 12: 0.05; the weight ratio of the EDC to the NHS in the coupling agent is 1: 1.2; the molar ratio of the chitosan to the N-methyl guanidinoacetic acid is 1: 0.5;

(2) modified chitosan: adding guanidinated chitosan and isopropanol into a reactor, heating to 75-80 ℃, stirring for 0.5h, slowly dropwise adding a 2, 3-epoxypropyltrimethylammonium chloride aqueous solution, carrying out heat preservation reaction for 6h, carrying out reduced pressure concentration to remove a solvent, then adding acetone, heating to 50 ℃, stirring for 1h, cooling to room temperature, stirring for 1h, filtering, and drying at 60 ℃ under reduced pressure for 20h to obtain modified chitosan; the weight ratio of the guanidino chitosan to the isopropanol to the acetone is 1: 8: 6; the weight ratio of the 2, 3-epoxypropyltrimethylammonium chloride to the guanidino chitosan is 0.3: 1.

In the aspect of cosmetics, quaternary ammonium salt groups are introduced into chitosan molecules to enhance the water solubility of the chitosan molecules, and the more quaternary ammonium salt groups are introduced into the chitosan molecules, the stronger the hydration capability of the chitosan molecules is, and the stronger the water holding capability is.

The chitosan quaternary ammonium salt has no cytotoxicity, no hemolysis, no sensitization, excellent biocompatibility and film forming property, can fully maintain nutrient components, and can form a natural barrier on the epidermis of a human body due to the good film forming property, thereby blocking or weakening the damage of ultraviolet rays, germs and the like to the skin and having good bacteriostatic and antibacterial properties. The chitosan film quaternary ammonium salt is mainly characterized by excellent hygroscopicity and moisture retention, and is considered to be a good substitute of hyaluronic acid due to the similarity of the structure and the moisture retention mechanism of the hyaluronic acid.

In one embodiment, the cosmetic adjuvants in component C further comprise dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea.

Ninety percent of the human skin is weaker in activity, darker, unbalanced in water and oil, dry, fine lines, wrinkles and loss of luster.

The dendrobium officinale extract has the effects of good moisturizing effect, capabilities of fading fine lines, keeping moisture for a long time, repairing damaged skin and the like; the aloe extract has antibacterial, antiinflammatory, moistening, skin caring, stomach invigorating, diarrhea relieving, heart tonifying, blood circulation promoting, immunity and regeneration promoting, immunity and anti-tumor, toxic materials clearing away, antiaging, analgesic, tranquilizing, and sunscreen effects; promoting wound healing, regulating immunity, resisting oxidation, bacteria and virus; the bergamot extract can purify skin, diminish inflammation, astringe and shrink pores, and is helpful for healing acne wounds; the centella asiatica extract can tighten the connecting part of the epidermis and the dermis, can soften the skin, help promote the formation of collagen in the dermis, has the effect of tightening the skin, can help the healing of damaged tissues and tighten the skin, promotes the close connection between the epidermis and the dermis, inhibits the increase of fat cells, and prevents skin edema and obesity; the chayote extract also has good whitening, moisturizing and moisturizing effects on skin, and can enable the skin to recover the white, red and full health state after long-term use; the gelicaine in the selaginella extract has super-strong water locking capacity, enhances the moisture retention, elasticity and smoothness of skin, has an antioxidant function and a natural cell activator, has the functions of effectively purifying the muscle bottom, removing free radicals and blackhead grease dirt, activating skin cells and regeneration, maintaining pore refreshing, accelerating wound healing and tissue repair, accelerating the synthesis of an aging collagen precursor, reducing skin redness and resisting erythra.

The modified chitosan has the advantages that the modified chitosan is introduced with guanidino, so that the antibacterial property and water solubility of the chitosan are further improved, a certain flocculation effect is achieved, the action time of nutritional ingredients in the skin care composition is prolonged, the skin is moistened and activated, and meanwhile, water can be replenished and locked for a long time; by grafting 2, 3-epoxypropyl trimethyl ammonium chloride, the water solubility, the molecular hydration capability, the water holding capability and the bacteriostatic and antibacterial properties of the product are further enhanced.

The skin care composition disclosed by the invention has the effects of nourishing and moistening skin, activating skin, replenishing water and moisturizing, repairing and regenerating skin, fading fine lines, preventing allergy and allergy, maintaining skin metabolic balance, delaying cell aging, fading pigmentation and dark yellow of a colorant, enabling skin to be fine, white, smooth and elastic, and also can replenish water, lock water and lift skin permanently.

The present invention will be specifically described below by way of examples. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention.

In addition, the raw materials used are commercially available from national chemical reagents, unless otherwise specified.

Example 1

The cosmetic is an emulsion, and the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility in the cosmetic comprises the following components in parts by weight:

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

the preparation method of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises the following steps:

The preparation method of the modified chitosan comprises the following steps:

Example 2

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.2: 7: 0.5: 1: 1.1: 0.3; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

the preparation method of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging and the preparation method of the modified chitosan are the same as the example 1.

Example 3

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 1: 7: 0.5: 3: 1.1: 1; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Example 4

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.5: 0.7; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Example 5

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 1.2: 0.2; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Example 6

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 2.0 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 9: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Example 7

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 6.4 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Example 8

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 5: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Example 9

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 11: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Example 10

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 5 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Example 11

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 20 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Comparative example 1

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic adjuvants and cosmetic matrix, wherein the cosmetic adjuvants in the component C comprise chitosan, surfactant, essence, dipotassium glycyrrhizinate, and bis (hydroxymethyl) imidazolidinyl urea; the chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Comparative example 2

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract and a bergamot extract, and the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract is 0.6: 7: 0.5; the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1, and the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 is 1: 0.6: 0.3; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

Comparative example 3

the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging comprises a component A, a component B and a component C; the component A is a dendrobium officinale extract, an aloe extract, a bergamot extract, a centella asiatica extract, a chayote extract and a selaginella tamariscina extract, wherein the weight ratio of the dendrobium officinale extract to the aloe extract to the bergamot extract to the centella asiatica extract to the chayote extract to the selaginella tamariscina extract is 0.6: 7: 0.5: 1.2: 1.1: 0.7; the component B is oligopeptide-1; the sum of the component A and the component B is 3.6 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the weight ratio of the component A to the component B is 8: 1; the component C comprises cosmetic auxiliary materials and a cosmetic matrix, wherein the cosmetic auxiliary materials in the component C comprise modified chitosan, a surfactant, essence, dipotassium glycyrrhizinate and bis (hydroxymethyl) imidazolidinyl urea; the modified chitosan in the component C accounts for 11 percent of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility; the surfactant is sodium stearate, and the essence is rose oil; the cosmetic matrix in the component C is ethanol, butanediol and water;

the preparation method of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging is the same as that of the example 1.

And (3) performance testing:

1. clinical efficacy observation of repair and regeneration

160 patients with dull and lusterless face and no systemic diseases 15-35 were selected and subjected to routine examination before trial: the electrocardiogram, the hematuria and the defecation are conventional, and the liver and kidney function are not abnormal. 160 people were randomly divided into two groups. 140 cases of the test group; the proportion of male and female in each group is similar in 20 control groups. Test group: after the face is cleaned every night, the cream provided in the embodiment is uniformly applied to the face to massage until the cream is naturally absorbed. Control group: after cleaning the skin in the morning and evening, a little vitamin E skin cream is smeared on the face, and is gently massaged for 1-3 minutes for continuous use for 30 days.

The therapeutic effect judgment standard is as follows:

and (3) curing: the tarnish and the dull luster are obviously lightened after the use.

The effect is shown: the tarnish and the dull luster are reduced after the use.

And (4) invalidation: the tarnish and the dull luster are not reduced after the use.

2. Study of moisturizing Effect

Taking 6 glass plates (7.5cm × 7.5.5 cm) stuck with 3M adhesive tapes, respectively weighing the glass plates as M₀Wherein 3 blocks are blank controls and 3 blocks are sample tests.

200 μ L of sample 1 and sample 2 were each dropped onto a glass plate with 3M adhesive tape, and the mass was M₁(to the nearest 0.0001g), homogenize the sample, place the glass plate in a constant humidity desiccator (saturated with ammonium sulfate), place the remaining 3 blank control glass plates together in a constant humidity desiccator.After standing for 8 hours, the glass plate was taken out and weighed to have a mass M₂The moisture retention rate was measured by the following formula.

Moisture retention rate [ [ (M)₂-M₀)/(M₁-M₀)]×100％

3. And (5) researching antibacterial and anti-inflammatory effects.

2 indicator bacteria of the test strains staphylococcus epidermidis and propionibacterium acnes are taken. Indicator bacteria cultured for 24h and indicator yeast cultured for 5 days were formulated into 106 cells/mL bacterial suspension with 50 mmol/LPBS.

Respectively inoculating the sample and the sample to be tested on culture medium plates of different test strains, culturing Propionibacterium acnes in an anaerobic incubator at 37 ℃ for 3-5 days, and culturing Staphylococcus epidermidis at 37 ℃ for 24h to observe the result. A blank was made with sterile water instead of the sample. The colony count was recorded and the inhibition rate was calculated as follows.

X＝[(A-B)/A]×100％

Wherein X is the bacteriostasis rate, A is the average colony number of the control sample, and B is the average colony number of the test sample. 4. The trial effect of the cosmetic is as follows: after 10 subjects used for 15 days, the wrinkles around the eyes and the length, depth and number of the wrinkles were observed.

Table 1 results of performance testing

From the data, the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging provided by the invention has the effects of strongly purifying the skin, nourishing and moistening, activating the skin, activating skin cells and regeneration, maintaining pore refreshing, accelerating wound healing and tissue repair, fading fine lines, moisturizing and preventing allergy and resisting allergy.

The foregoing examples are merely illustrative and serve to explain some of the features of the method of the present invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.

Claims

1. A skin care composition with the functions of repairing and regenerating, moisturizing and delaying senility is characterized by comprising a component A, a component B and a component C;

the component A is herba Dendrobii extract, Aloe extract, fructus Citri Sarcodactylis extract, herba Centellae extract, fructus Sechii edulis extract, and herba Selaginellae extract; the weight ratio of the dendrobium officinale extract to the aloe extract, the bergamot extract, the centella asiatica extract, the chayote extract and the selaginella tamariscina extract in the component A is (0.2-1): (3-8): (0.3-0.7): (1-3): (0.5-2): (0.3-1);

the oligopeptide in the component B is oligopeptide-1, palmitoyl tripeptide-5 and acetyl pentapeptide-1; the weight ratio of the oligopeptide-1 to the palmitoyl tripeptide-5 and the acetyl pentapeptide-1 in the component B is 1: (0.5-1.2): (0.2-0.7);

the component C is a cosmetic auxiliary material and a cosmetic matrix; the cosmetic auxiliary materials comprise one or more of modified chitosan, surfactant, essence and colorant; the modified chitosan is prepared by taking N-methyl guanidinoacetic acid as a raw material, performing catalytic reaction to prepare guanidino chitosan, and grafting 2, 3-epoxypropyl trimethyl ammonium chloride.

2. The skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging as claimed in claim 1, wherein the weight ratio of the dendrobium officinale extract to the aloe extract, the bergamot extract, the centella asiatica extract, the chayote extract and the selaginella tamariscina extract in the A component is 0.6: 7: 0.5: 1.2: 1.1: 0.7.

3. the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging as claimed in claim 1, wherein the sum of the A component and the B component is 2% -10% of the weight of the skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging.

4. The skin care composition with the functions of repairing and regenerating, moisturizing and delaying aging as claimed in claim 1, wherein the weight ratio of the A component to the B component is (5-12): 1.

5. the skin care composition with the functions of rejuvenation, moisturizing and aging delaying as claimed in any one of claims 1 to 4, wherein the skin care composition with the functions of rejuvenation, moisturizing and aging delaying is applied to a mask, an eye cream, a face cream, an essence, a face cleanser, a stock solution, a toner, an emulsion, a cream, a hydrosol, a sun screen or a BB cream.

6. A method for preparing a skin care composition with the functions of repairing and regenerating skin, moisturizing skin and delaying senility according to any one of claims 1 to 4, which is characterized by comprising the following steps: