CN107647938A - A kind of combined type renal artery stent - Google Patents
A kind of combined type renal artery stent Download PDFInfo
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- CN107647938A CN107647938A CN201710994696.8A CN201710994696A CN107647938A CN 107647938 A CN107647938 A CN 107647938A CN 201710994696 A CN201710994696 A CN 201710994696A CN 107647938 A CN107647938 A CN 107647938A
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- Prior art keywords
- renal artery
- combined type
- artery stent
- segmentation
- type renal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/077—Stent-grafts having means to fill the space between stent-graft and aneurysm wall, e.g. a sleeve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Prostheses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The invention discloses a kind of combined type renal artery stent, the combined type renal artery stent can select a number of segmentation support to form the renal artery stent of appropriate length, to meet patient personalized demand according to lesion locations and scope；Simultaneously, connected due to employing projection between each segmentation support with the mode of groove clamping, and there is impermeable X ray label around it, it is achieved thereby that quick assembling and being accurately positioned, the medication coat on its surface can reduce the generation of various complication by sustained release, reduce body lumen ISR risk；In addition, the combined type renal artery stent can also carry out natural torsion according to the design feature of the human body arteria renalis, to more conform to tissue adaptability, make implantation more safe and stable.
Description
Technical field
The present invention relates to medical implanted prosthetics field, more particularly to a kind of combined type renal artery stent.
Background technology
The arteria renalis (renal artery) is divided into left renal artery and right renal artery, is vertically separated by abdominal aorta, in intestines system
Sent on film below artery between 1-2cm, the one or two lumbar vertebrae, enter left and right kidney through the hilus renalis respectively.The arteria renalis is both the nutrition blood of kidney
Pipe, it is the functioning blood vessel of kidney again.And recently as the arrival of aging society, RAS (renal artery
Stenosis, RAS) the incidence of disease constantly raise, RAS can cause secondary hypertension and ischemic nephropathy, and
The Important cause of disease of Senile Renal Failure.Wherein narrow severe patient can accelerate the process of renal failure, rear bad how
Effectively treatment is carried out to the disease turns into the focus of current medical worker research.RAS mainly moves by atherosclerotic renal artery stenosis, greatly
Caused by the reason such as arteries and veins inflammation and fibromuscular dysplasia.Research shows that atherosclerosis is the main disease of RAS
Cause, proportion are up to 95%, traditional percutaneous transluminal renal angioplasty（ercutaneous transluminal renal
angioplasty, PTRA）When treating RAS, there is higher initial stage and late restenosis rate.In order to overcome
, there is arteria renalis intracavity stent implantation (PTRA+stent, PTRAS) in this shortcoming, the technology have it is higher first
Technique successful rate, while study and show that this disease of stenting also achieves preferable long-term recanalization rate, with arteria renalis intracavitary
The extensive development of Stent, most hypertension caused by RAS and renal function exacerbation patient is set to benefit from it.Due to peace
Entirely, few intercurrent disease, arteria renalis intracavity stent implantation is as the important alternatives of surgical kidney artery reconstruction art at present.
But renal artery stent develops also very immature at home, only a small number of producers can produce, and be more imitated state
Outer like product, Clinical practice are substituted using periphery support (such as common iliac artery support) more still based on import external product,
Specifically for actually rare on the stent market of the arteria renalis, and the characteristics of due to arteria renalis lesion, opening is frequently located in so that branch
There must be 1-2mm to project to main artery after frame implantation, this significantly affects haemodynamics form, is especially needing bilateral support
Influenceed after implantation more very, and existing support size is fixed in addition, and independent assortment can not be realized according to lesion locations, changes stent length
And free bend.
Based on above mentioned problem, it is desirable to provide one kind can independent assortment so as to changing stent length and can as needed
The renal artery stent of medicament slow release is carried out, body lumen ISR risk can be reduced, be implanted into safe characteristic by having.
The content of the invention
The present invention solves the technical problem of provide one kind can independent assortment so as to changing its length as needed
Renal artery stent, before stenter to implant, choose the support that a number of brace sections are combined into suitable length as needed, plant
It is fashionable that medicament slow release can be carried out according to arteria renalis own structural characteristics free bend after implantation, so as to preferably eliminate people
Body RAS, strengthen the safety and stability of stenter to implant.The support is in segmented hollow tubular structure, if it includes
The dry netted segmentation holder combination of section is formed, and each support that is segmented be hollow columnar structures, have the first end of non-network with
Second end, the first end outer edge of each segmentation support have at least two arc-shapeds raised, and the second end inside edge has
At least two can accommodate the raised groove, the second end of each another segmentation support of first end insertion for being segmented support, lead to
The raised and groove clamping is crossed, forms combined type renal artery stent, it is not necessary to enter using connection ring, connecting rod or suture etc.
Row connection, the combined type renal artery stent after assembling is in integrally hollow columnar structures, and the mellow and full nothing of smooth outer surface substantially connects
Seam gap, overlay film can be carried out to bare bracket as needed.
The segmentation support is made by elastomeric material, and the elastomeric material includes elastic metallic material and elasticity is non-
Metal material；The elastic metallic material includes medical stainless steel, titanium magnesium alloy, Nitinol, cochrome, silver alloy, magnesium
Alloy etc., the resilient nonmetallic material include polytetrafluoroethylene (PTFE), polyester fiber, polyamide, polypropylene, polycaprolactone, poly- breast
Acid, polyurethane, polybutadiene, rubber, collagen etc..
The combined type renal artery stent system typically saves segmentation support by 2-5 and formed, the first end of the segmentation support
With the second end equal length, the 10% to 20% of segmentation total stent length where accounting for respectively, wherein first end diameter is less than place point
The diameter of section rack body, it can be inserted freely into the second end of another segmentation support without being interference fitted.
The periphery of the segmentation support is coated with medication coat, and the medication coat is coated uniformly on the segmentation support sheet
The periphery of body, the first end do not have medication coat.Medication coat can be sustained after the human body arteria renalis is implanted into, slow-release time
At -3 years 1 year.
The medication coat includes but is not limited to immunomodulator, anticarcinogen, antiblastic, anti-inflammatory agent, antithrombotic
Medicine, anti-platelet agents, antifungal agent, antidiabetic, antihyperlipidemic drug, anti-angiogenic agent, angiogenic agent, anti-high blood
Pressing, antidepressants, antiepileptic, analgestic, wound healing promoting medicine, the medicine or above-mentioned of metabolic regulation medicine or other species
The combination of medicine, modification or variant using analog, prodrug, derivative, precursor, fragment, salt or other pharmaceutical formulations, also all
It is included in the present invention.
There is impermeable X ray label around the raised and groove, be easy under X-ray examination enter each segmentation support
Row implantation assembling, can also be combined before implantation as needed.
Beneficial effects of the present invention:
The combined type renal artery stent of the present invention is formed as a result of segmentation holder combination, therefore can be according to lesion locations and model
The renal artery stent for selecting a number of segmentation support to form appropriate length is enclosed, to meet patient personalized demand, meanwhile, by
Projection is employed between each segmentation support to connect with the mode of groove clamping, and there is impermeable X ray label around it,
It is achieved thereby that quick assembling and being accurately positioned, the medication coat on its surface can reduce the generation of various complication by sustained release,
Body lumen ISR risk is reduced, in addition, the combined type renal artery stent can also enter according to the design feature of the human body arteria renalis
Row natural torsion, to more conform to tissue adaptability, make implantation more safe and stable.
Brief description of the drawings
Fig. 1 is a kind of structural representation of combined type renal artery stent system of the present invention；
Fig. 2 is the structural representation of present invention segmentation support；
The mark of each part is as follows in accompanying drawing：1st, combined type renal artery stent；2nd, it is segmented support；3rd, first end；4th, the second end；5、
It is raised；6th, groove.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.It is based on
Embodiment in the present invention, those of ordinary skill in the art are obtained every other under the premise of creative work is not made
Embodiment, belong to the scope of protection of the invention.
Embodiment 1：
As shown in figure 1, the present invention combined type renal artery stent 1 be in segmented hollow tubular structure, it include some sections it is netted
It is segmented the combination of support 2 to form, each support 2 that is segmented is hollow columnar structures, the end of first end 3 and second with non-network
6, the outer edge of first end 3 of each segmentation support 2 has at least two arc-shaped projections 5, and the second end inside edge has extremely
Few two can accommodate raised 5 groove 4, and each first end 3 for being segmented support inserts the second end 6 of another segmentation support,
By described raised 5 and the clamping of groove 4, combined type renal artery stent 1 is formed, it is not necessary to use connection ring, connecting rod or suture
Line etc. is attached.Its independent assortment enables renal artery stent to change its length as needed, in stenter to implant
Before, choose the support that a number of brace sections are combined into suitable length as needed, can be tied according to the arteria renalis itself during implantation
Structure feature free bend, medicament slow release can be carried out after implantation, so as to preferably eliminate human body RAS, enhancing support is planted
The safety and stability entered.
Combined type renal artery stent after assembling is in integrally hollow columnar structures, and the mellow and full nothing of smooth outer surface substantially connects
Seam gap, overlay film can be carried out to bare bracket as needed.
The segmentation support 2 is made by elastic metallic material, and the elastic metallic material includes medical stainless steel, titanium
Magnesium alloy, Nitinol, cochrome, silver alloy, magnesium alloy etc..
The combined type renal artery stent 1 typically saves segmentation support 2 by 2-5 and formed, the first end 3 of the segmentation support 2
With the equal length of the second end 6, the 10% to 20% of the segmentation total length of support 2 where accounting for respectively, the wherein diameter of first end 3 is less than place
The diameter of the body of support 2 is segmented, it can be inserted freely into the second end 6 of another segmentation support without being interference fitted.
The periphery of the segmentation support 2 is coated with medication coat, and the medication coat is coated uniformly on the segmentation support 2
The periphery of body, the first end 3 do not have medication coat.Medication coat can be sustained after the human body arteria renalis is implanted into, sustained release
Time is 1-3.
The medication coat includes but is not limited to immunomodulator, anticarcinogen, antiblastic, anti-inflammatory agent, antithrombotic
Medicine, anti-platelet agents, antifungal agent, antidiabetic, antihyperlipidemic drug, anti-angiogenic agent, angiogenic agent, anti-high blood
Pressing, antidepressants, antiepileptic, analgestic, wound healing promoting medicine, the medicine or above-mentioned of metabolic regulation medicine or other species
The combination of medicine, modification or variant using analog, prodrug, derivative, precursor, fragment, salt or other pharmaceutical formulations, also all
It is included in the present invention.
Described raised 5 and groove 4 around there is impermeable X ray label, be easy under X-ray examination to each segmentation support
2 carry out implantation assembling, can also be combined before implantation as needed.
Embodiment 2：
As shown in figure 1,1 most of structure of combined type renal artery stent of the present invention is same as Example 1, unlike, this reality
Apply described in example be segmented support 2 be made by resilient nonmetallic material, the resilient nonmetallic material include polytetrafluoroethylene (PTFE),
Polyester fiber, polyamide, polypropylene, polycaprolactone, PLA, polyurethane, polybutadiene, rubber, collagen etc..
Embodiments of the invention are the foregoing is only, are not intended to limit the scope of the invention, it is every to utilize this hair
The equivalent structure or equivalent transformation that bright description is made, or other related technical areas are directly or indirectly used in,
Similarly it is included within the scope of the present invention.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of changes, modification can be carried out to these embodiments, replace without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (7)
1. a kind of combined type renal artery stent, the combined type renal artery stent is in segmented hollow tubular structure, including some
The netted segmentation holder combination of section is formed；Each segmentation support be hollow columnar structures, first end with non-network and the
Two ends, the first end outer edge of each segmentation support have at least two arc-shapeds raised, and the second end inside edge has extremely
Few two can accommodate the raised groove, the second end of each another segmentation support of first end insertion for being segmented support, pass through
The raised and groove clamping, forms combined type renal artery stent.
2. combined type renal artery stent according to claim 1, the segmentation support is made by elastomeric material, described
Elastomeric material includes elastic metallic material and resilient nonmetallic material；The elastic metallic material includes medical stainless steel, titanium
Magnesium alloy, Nitinol, cochrome, silver alloy, magnesium alloy, the resilient nonmetallic material include polytetrafluoroethylene (PTFE), polyester
Fiber, polyamide, polypropylene, polycaprolactone, PLA, polyurethane, polybutadiene, rubber, collagen.
3. combined type renal artery stent according to claim 2, the combined type renal artery stent saves segmentation support by 2-5
Composition, the first end and the second end equal length of the segmentation support, the 10% to 20% of segmentation total stent length where accounting for respectively,
Wherein first end diameter be less than place segmentation rack body diameter, its can be inserted freely into it is another segmentation support the second end and
It is not interference fitted.
4. combined type renal artery stent according to claim 3, the periphery of the segmentation support is coated with medication coat, institute
The periphery that medication coat is coated uniformly on the segmentation rack body is stated, the first end does not have medication coat.
5. combined type renal artery stent according to claim 4, the medication coat include but is not limited to immunomodulator,
Anticarcinogen, antiblastic, anti-inflammatory agent, antithrombotic, anti-platelet agents, antifungal agent, antidiabetic, anti-hyperlipidemia
Medicine, anti-angiogenic agent, angiogenic agent, antihypertensive, antidepressants, antiepileptic, analgestic, wound healing promoting medicine,
The combination of the medicine or said medicine of metabolic regulation medicine or other species.
6. the combined type renal artery stent according to any one of claims 1 to 3, with not around the raised and groove
Saturating X ray label, it is easy under X-ray examination carry out implantation assembling to each segmentation support.
7. the combined type renal artery stent according to any one of claims 1 to 3, with not around the raised and groove
Saturating X ray label, it is easy under X-ray examination be combined each segmentation support before implantation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710994696.8A CN107647938A (en) | 2017-10-23 | 2017-10-23 | A kind of combined type renal artery stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710994696.8A CN107647938A (en) | 2017-10-23 | 2017-10-23 | A kind of combined type renal artery stent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107647938A true CN107647938A (en) | 2018-02-02 |
Family
ID=61119198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710994696.8A Withdrawn CN107647938A (en) | 2017-10-23 | 2017-10-23 | A kind of combined type renal artery stent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107647938A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110731834A (en) * | 2019-10-25 | 2020-01-31 | 郑州美港高科生物科技有限公司 | Iron-base alloy renal artery stent |
| CN112107399A (en) * | 2020-09-22 | 2020-12-22 | 卢飞飞 | Intracardiac branch of academic or vocational study prevents intervention support of massive haemorrhage |
| CN113456323A (en) * | 2021-07-23 | 2021-10-01 | 贺迎坤 | Blood flow guiding device with coating |
-
2017
- 2017-10-23 CN CN201710994696.8A patent/CN107647938A/en not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110731834A (en) * | 2019-10-25 | 2020-01-31 | 郑州美港高科生物科技有限公司 | Iron-base alloy renal artery stent |
| CN112107399A (en) * | 2020-09-22 | 2020-12-22 | 卢飞飞 | Intracardiac branch of academic or vocational study prevents intervention support of massive haemorrhage |
| CN113456323A (en) * | 2021-07-23 | 2021-10-01 | 贺迎坤 | Blood flow guiding device with coating |
| CN113456323B (en) * | 2021-07-23 | 2023-07-25 | 贺迎坤 | Blood flow guiding device with coating |
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Application publication date: 20180202 |
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