CN107596474A - Blood plasma degreasing purifying treatment method - Google Patents
Blood plasma degreasing purifying treatment method Download PDFInfo
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- CN107596474A CN107596474A CN201711056542.0A CN201711056542A CN107596474A CN 107596474 A CN107596474 A CN 107596474A CN 201711056542 A CN201711056542 A CN 201711056542A CN 107596474 A CN107596474 A CN 107596474A
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Abstract
Blood plasma degreasing purifying treatment method, including：Centrifugal treating is carried out to blood first, separates blood cells and blood plasma, then by the blood plasma isolated by condensing, thawing, calcium ion induces, freezing, Wen Rong and precipitation, its improvements over the prior art are：It is placed on to soak 5 15 minutes in normal temperature flowing tank after precipitation and cools, then carry out centrifugal treating, afterwards purifies blood plasma with the porous pottery for being attached with nano-silver catalyst or rare earth catalyst.The present invention can remove various harmful substances such as lead, cadmium, mercury, arsenic etc. in blood plasma while blood plasma degreasing, while can aoxidize blood fat again, reduce free radical, improve degreasing effect, also purified blood plasma, improve blood plasma quality.
Description
Technical field
The present invention relates to blood processing, particularly blood plasma degreasing purifying treatment method.
Background technology
Because fat metabolism or operating exception make blood plasma one or more lipid, higher than hyperlipidemia is just frequently referred to, lipid is not
Molten or be slightly soluble in water and must be combined with protein and exist with lipoprotein form, therefore, hyperlipidemia is often hyperlipoprotememia
（hyperlipoproteinemia）, show as hypercholesterolemia, hypertriglyceridemia or both and have concurrently.If blood fat mistake
It is more, " blood is thick " is easily caused, is deposited on vascular wall, gradually forms small patch（It is exactly " the Atherosclerosis that we often say
Change "）, these " patches " increase, increased, gradually block blood vessel, make blood flow slack-off, and blood flow is interrupted when serious, and such case is such as
Fruit occurs, in heart, just to cause coronary heart disease；Occur, in brain, headstroke just to occur；If blocking optical fundus blood vessel, eyesight will be caused
Decline, blindness；If it happens in kidney, renal arteriosclerosis, renal failure will be caused;Occur in lower limb, it may appear that limbs
Necrosis, fester, in addition, high fat of blood can trigger hypertension, induce gall stone, pancreatitis, aggravate hepatitis, cause male's sexual
The diseases such as obstacle, senile dementia.
Because modern life rhythm accelerates, erratically live, intemperate diet, hyperlipidemia patient is increasingly
It is more.Therefore, reduce blood fat and receive increasing attention.The method of extracorporeal blood lipid-loweringing processing is also more and more.HHP degreasings
Viscosity reduction is treated, and is to select combined biofilm, and blood is separated into haematoblast and blood plasma, wherein blood plasma using the principle of centrifugation
Removal lipid composition through biomembrane selectivity, the also defeated the Huis' body of other blood constituents.Patient removes treatment by a blood fat
Afterwards, triglyceride and T-CHOL are close to normal.
CN1363401 discloses a kind of method of cleaning and balance therapy of blood, and centrifugal treating is carried out to blood, and separation bleeding is thin
Born of the same parents and blood plasma, by the blood plasma isolated by condensing, thawing, calcium ion is induced, freezing, the processing step of Wen Rong and precipitation are carried out
Remove blood fat, respectively by haemocyte and through fat removal step handle gained blood plasma vibrate and stirring under carry out ultraviolet light and
Laser quantum irradiates, and is oxygenated simultaneously in irradiation, and magnetized by electromagnetic field.Blood plasma is chilled, Wen Rong, add it is drug-induced, make
Blood fat and fibrinogen deposition separate out, can reach purification blood, degreasing stays the purpose of slurry, the blood being opposite in blood container is thin
Born of the same parents and through fat removal step handle gained blood plasma carry out ultraviolet irradiation, laser quantum radiation, be oxygenated and magnetize, strengthen blood
Oxygen saturation and cytoactive, blood can be purified, promote metabolism, improve hemorheology feature, enhancing blood purification balance
Effect.
However, the above method is all also complex, and no and purification combines.
The content of the invention
The defects of in order to overcome prior art, make the processing of blood plasma degreasing more simple and efficient, and reach clean-up effect, this
Invention provides a kind of blood plasma degreasing purifying treatment method.
The present invention realizes goal of the invention using following technical proposals.
Blood plasma degreasing purifying treatment method, including：Centrifugal treating is carried out to blood first, separates blood cells and blood plasma,
Then by the blood plasma isolated by condensing, thawing, calcium ion induce, freezing, Wen Rong and precipitation, its improvements over the prior art
It is：Being placed on immersion 5-15 minutes in normal temperature flowing tank after precipitation cools, then carries out centrifugal treating, afterwards by blood plasma with attached
The porous pottery purification of nano-silver catalyst or rare earth catalyst.
Further, condensation temperature is subzero 5 degree ~ subzero 10 degree, 12 ~ 24 hours time.
Further, thaw and carried out in flowing normal temperature tank.
Further, the calcium ion induction is to add 0.5% calcium chloride solution according to plasma volume, and 0.5% calcium chloride solution is used
Measure and be：Plasma volume/17.08, plasma volume measurement unit for gram, 0.5% calcium chloride solution measurement unit is milliliter.
Further, cryogenic temperature is subzero 5 degree ~ subzero 10 degree, 12 ~ 24 hours time.
Further, Wen Rong and precipitation include：It is put into and is dipped to blood plasma in the constant temperature water tank of 36-38 DEG C of water temperature and thaws completely,
Continue to be dipped to be formed untill chyle sample pellet no longer increases.
Preferably, porous pottery purification includes porous ceramic plate filtering or mixed with porous ceramic grain to be ultrasonically treated.
In order to obtain more preferable effect and easily facilitate later separation, of the invention one preferably：Porous ceramic grain particle diameter
For 0.2 ~ 2mm, porous ceramic grain dosage is 1st/10th to ten/20th of blood plasma.
Further, sonication treatment time 10 ~ 30 minutes.
Nano-silver catalyst or rare earth catalyst can remove various harmful substances such as lead, cadmium, mercury, arsenic etc. in blood plasma,
Blood fat can be aoxidized again simultaneously, reduce free radical, and act on fast, positive effect.Porous ceramic plate filtering synthetic filter and catalysis
Double action, be ultrasonically treated and promote fully contacting for blood plasma and catalyst, raising effect.Porous ceramic plate and porous ceramic grain have
Fabulous adsorptivity, the product after various nuisances and catalyst treatment is adsorbed, more improves clean-up effect.
The present invention can remove various harmful substances such as lead, cadmium, mercury, arsenic etc., while again in blood plasma while blood plasma degreasing
Blood fat can be aoxidized, free radical is reduced, improves degreasing effect, also purified blood plasma, improve blood plasma quality.
Embodiment
Embodiment 1
Centrifugal treating is carried out to blood first, separates blood cells and blood plasma.
By separated good plasma bags heat sealing, the name of patient, sex, age, diagnosis numbering are write, is placed on balance
On weigh, then the blood plasma gross weight weighed up is subtracted to the tare weight of blood plasma transfering bag, then the net weight of blood plasma is write in blood bag.
Then blood plasma is put into freezing 24 hours in subzero 5 degree ~ subzero 10 degree of refrigerator-freezer（And write date, time）.Next day taking-up is put
Punching is thawed completely to plasma bags in normal temperature flowing tank, and the degreasing for needing to add then is calculated according to the total amount in plasma bags
The amount of the calcium chloride of decoction 0.5%.Calculation formula is as follows：（Total plasma volume -- slurry bag hides weight）（g）/ 17.08, produce needed for plus 0.5%
Calcium chloride amount（ml）, by the heat sealing, and write dosing date and time mark again of the plasma bags after addition decoction, then blood plasma
Bag is put into refrigerator（Subzero 5 degree ~ subzero 10 degree）Frost 24 hours.24 hours plasma bags are freezed by second, after taking-up, are put
Enter water temperature to soak one hour in 36-38 DEG C of constant temperature water tank again, 20-30 minutes after blood plasma thaws completely, breast is gradually formed in bag
Rotten sample pellet, if soak time can be extended to there is agglomerate by not forming agglomerate thing, untill agglomerate no longer increases.Take out slurry
Bag, being placed on immersion 5-15 minutes in normal temperature flowing tank cool, is the agglomerate that a visible coating is wrapped up in through centrifugal treating, in bag,
Blood plasma is in bright in bag.
Blood plasma is released afterwards, mixes, is surpassed with the porous ceramic grain for being attached with nano-silver catalyst or rare earth catalyst
Sonication 15 minutes.Porous ceramic grain particle diameter is 1mm, and porous ceramic grain dosage is 1/10th of blood plasma.
Blood plasma can by the purification of above-mentioned degreasing is fed back into the human body.
Embodiment 2
It is with the difference of embodiment 1, after blood plasma is released, using being attached with nano-silver catalyst or rare earth catalyst
Porous ceramic plate filtering.After filtering, blood plasma can is fed back into the human body.
Claims (9)
1. blood plasma degreasing purifying treatment method, including：Centrifugal treating is carried out to blood first, separates blood cells and blood plasma, so
Afterwards by the blood plasma isolated by condensing, thawing, calcium ion induce, freezing, Wen Rong and precipitation, it is characterised in that：It is additionally included in
Being placed on immersion 5-15 minutes in normal temperature flowing tank after precipitation cools, then carries out centrifugal treating, afterwards receives blood plasma with being attached with
The purification of the porous pottery of rice silver catalyst or rare earth catalyst.
2. blood plasma degreasing purifying treatment method according to claim 1, it is characterised in that：Condensation temperature is subzero 5 degree ~ zero
It is lower 10 degree, 12 ~ 24 hours time.
3. blood plasma degreasing purifying treatment method according to claim 1, it is characterised in that：Thaw in flowing normal temperature tank
Carry out.
4. blood plasma degreasing purifying treatment method according to claim 1, it is characterised in that：Calcium ion induction be according to
Total plasma volume adds 0.5% calcium chloride solution, and 0.5% calcium chloride solution dosage is：Plasma volume/17.08, plasma volume measurement unit are
Gram, 0.5% calcium chloride solution measurement unit is milliliter.
5. blood plasma degreasing purifying treatment method according to claim 1, it is characterised in that：Cryogenic temperature is subzero 5 degree ~ zero
It is lower 10 degree, 12 ~ 24 hours time.
6. blood plasma degreasing purifying treatment method according to claim 1, it is characterised in that：Wen Rong and precipitation include：It is put into
Blood plasma is dipped in the constant temperature water tank of 36-38 DEG C of water temperature to thaw completely, continues to be dipped to form chyle sample pellet and no longer increase
Untill big.
7. blood plasma degreasing purifying treatment method according to claim 1, it is characterised in that：Porous pottery purification includes porous pottery
Plate is filtered or mixed with porous ceramic grain and is ultrasonically treated.
8. blood plasma degreasing purifying treatment method according to claim 7, it is characterised in that：Porous ceramic grain particle diameter be 0.2 ~
2mm, porous ceramic grain dosage are 1st/10th to ten/20th of blood plasma.
9. blood plasma degreasing purifying treatment method according to claim 7, it is characterised in that：10 ~ 30 points of sonication treatment time
Clock.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711056542.0A CN107596474A (en) | 2017-11-01 | 2017-11-01 | Blood plasma degreasing purifying treatment method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711056542.0A CN107596474A (en) | 2017-11-01 | 2017-11-01 | Blood plasma degreasing purifying treatment method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117696017A (en) * | 2024-02-05 | 2024-03-15 | 四川大学华西医院 | Blood purification adsorption modified material and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1363401A (en) * | 2002-02-01 | 2002-08-14 | 王厚文 | Method and equipment for cleaning and balance therapy of blood |
| CN1958136A (en) * | 2006-10-17 | 2007-05-09 | 浙江大学 | Antibacterial hollow-fiber membrane, preparation method and application |
| CN103402563A (en) * | 2010-11-02 | 2013-11-20 | Ic创新有限公司 | Electrosorption and decomposition device for the purification of blood and other fluids |
| CN105307698A (en) * | 2013-06-07 | 2016-02-03 | 日产化学工业株式会社 | Blood filter and method for producing same |
| JP2017104853A (en) * | 2015-11-30 | 2017-06-15 | 東レ株式会社 | Phosphorus adsorbent, porous fiber, and phosphorus adsorption column |
-
2017
- 2017-11-01 CN CN201711056542.0A patent/CN107596474A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1363401A (en) * | 2002-02-01 | 2002-08-14 | 王厚文 | Method and equipment for cleaning and balance therapy of blood |
| CN1958136A (en) * | 2006-10-17 | 2007-05-09 | 浙江大学 | Antibacterial hollow-fiber membrane, preparation method and application |
| CN103402563A (en) * | 2010-11-02 | 2013-11-20 | Ic创新有限公司 | Electrosorption and decomposition device for the purification of blood and other fluids |
| CN105307698A (en) * | 2013-06-07 | 2016-02-03 | 日产化学工业株式会社 | Blood filter and method for producing same |
| JP2017104853A (en) * | 2015-11-30 | 2017-06-15 | 東レ株式会社 | Phosphorus adsorbent, porous fiber, and phosphorus adsorption column |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117696017A (en) * | 2024-02-05 | 2024-03-15 | 四川大学华西医院 | Blood purification adsorption modified material and preparation method thereof |
| CN117696017B (en) * | 2024-02-05 | 2024-05-07 | 四川大学华西医院 | Blood purification adsorption modified material and preparation method thereof |
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