CN107582844A - A kind of pill medicine for treating diabetes and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of pill medicine for treating diabetes provided according to the understanding mechanism of TCM treatment of diabetes, each component and its mass parts ratio of the medicine are as follows：90~350g of the Radix Astragali, 60~150g of Fructus Corni, 90~160g of Snakegourd Fruit, 80~160g of the bighead atractylodes rhizome, 100~350g of radix rehmanniae recen, 8~12g of gynostemma pentaphylla, 150~250g of Poria cocos, 80~160g of Radix Angelicae Sinensis, 150~350g of Gorgon fruit, 50~150g of the root of herbaceous peony, 60~150g of Semen Cuscutae, 90~150g of loguat leaf, 50~150g of potentilla discolor, 60~120g of wrinkled giant hyssop, 30~120g of hawthorn, 150~300g of mulberries, 100~150g of sealwort, 30~100g of Fructus meliae toosendan, 150~300g of Radix cynanchi wilfordii, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of pill medicine for treating diabetes and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for treating diabetes, particularly for glycosuria The field of the pill medicine that patient uses and preparation method thereof.

Background technology

Doctor thinks：Diabetes are one group of metabolic diseases characterized by hyperglycaemia.Hyperglycaemia is due to then insulin Hyposecretion or its biological agent are damaged, or both have concurrently and cause.Long-standing hyperglycaemia during diabetes, causes various groups Knit, particularly eye, kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.

Clinical manifestation：

A. drink, diuresis more than, eat and become thin more

Occur typical " three-many-one-little " symptom during severe hyperglycemia, be more common in type 1 diabetes.Generation ketosis or DKA When " three-many-one-little " symptom become apparent.

B. fatigue and weak, it is fat

It is more common in diabetes B.Diabetes B premorbid often has obesity, if cannot diagnose in time, body weight can be gradually reduced.

So, it is that those skilled in the art are urgently to be resolved with regard to how to find a kind of Chinese medicine composition for imitating treatment diabetes The problem of.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment diabetes, people gradually appreciate Chinese traditional treatment The advantages of diabetes, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment sugar The present situation of disease is urinated, the purpose of the present invention is to be to provide a kind of pill medicine for treating diabetes, to solve diabetic's morning The problem of day gets well.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can be had Effect treats above-mentioned diabetes.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：A kind of ball for treating diabetes is provided Agent medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows：

90~350g of the Radix Astragali, 60~150g of Fructus Corni, 90~160g of Snakegourd Fruit, 80~160g of the bighead atractylodes rhizome, 100~350g of radix rehmanniae recen, strand 8~12g of stock indigo plant, 150~250g of Poria cocos, 80~160g of Radix Angelicae Sinensis, 150~350g of Gorgon fruit, 50~150g of the root of herbaceous peony, Semen Cuscutae 60~ 150g, 90~150g of loguat leaf, 50~150g of potentilla discolor, 60~120g of wrinkled giant hyssop, 30~120g of hawthorn, 150~300g of mulberries, Huang 100~150g of essence, 30~100g of Fructus meliae toosendan, 150~300g of Radix cynanchi wilfordii, auxiliary material：Appropriate starch.

A kind of pill medicine for treating diabetes and preparation method thereof, it is characterised in that each component of the medicine and Its mass parts is than as follows：

100~310g of the Radix Astragali, 70~130g of Fructus Corni, 100~130g of Snakegourd Fruit, 90~130g of the bighead atractylodes rhizome, 115~310g of radix rehmanniae recen, 9~11g of gynostemma pentaphylla, 180~220g of Poria cocos, 90~130g of Radix Angelicae Sinensis, 180~310g of Gorgon fruit, 58~130g of the root of herbaceous peony, Semen Cuscutae 70 ~130g, 100~130g of loguat leaf, 58~130g of potentilla discolor, 70~105g of wrinkled giant hyssop, 38~105g of hawthorn, mulberries 180~ 260g, 115~130g of sealwort, 38~90g of Fructus meliae toosendan, 180~260g of Radix cynanchi wilfordii, auxiliary material：Appropriate starch.

A kind of pill medicine for treating diabetes and preparation method thereof, it is characterised in that the medicine of " preferred plan " Each component and its mass parts than as follows：

Radix Astragali 280g, Fructus Corni 115g, Snakegourd Fruit 115g, bighead atractylodes rhizome 115g, radix rehmanniae recen 280g, gynostemma pentaphylla 10g, Poria cocos 200g, Radix Angelicae Sinensis 115g, Gorgon fruit 280g, root of herbaceous peony 115g, Semen Cuscutae 115g, loguat leaf 115g, potentilla discolor 115g, wrinkled giant hyssop 95g, hawthorn 95g, mulberries 230g, sealwort 118g, Fructus meliae toosendan 80g, Radix cynanchi wilfordii 230g, auxiliary material：Appropriate starch.

A kind of pill medicine for treating diabetes and preparation method thereof, it is characterised in that methods described comprises the following steps It is prepared：

A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats With；

B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.7mm~4.0mm）, and then dry, sealed packaging is Can.

A kind of pill medicine for treating diabetes and preparation method thereof, it is characterised in that the instructions of taking is：It will prepare Good herb liquid point is taken for two days, morning and evening sub-service, dosage 180ml（Milliliter）/ time, warmly take after meal（Taboo：1. serious renal function Incomplete, diabetes mellitus DKA, stupor, insulin-dependent diabetic and pregnant woman's disabling；Prison is please noted during medication Blood glucose is surveyed, and dosage is adjusted according to blood glucose）, while the conditioning that is careful in one's diet, three meals in a day want rule, control food-intake and dieting, Eaten such as frying with high the lacking containing sugar, 25 days are a course for the treatment of, and 3~4 courses for the treatment of of taking medicine, blood glucose is substantially delayed or controlled, So as to reduce the generation of complication.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

The Radix Astragali, nature and flavor：Sweet, tepor, there is the effect of invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation, for treating the deficiency of vital energy Weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, The diseases such as flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes；

Fructus Corni, nature and flavor：Sour, puckery, tepor, have and tonify the liver and kidney, the effect of puckery smart prevent prolapse, for treating dizziness and tinnitus, waist and knee Ache, impotence and seminal emission, enuresis frequent micturition, under uterine bleeding band, profuse sweating collapse, Heat Diabetes；

Snakegourd Fruit, nature and flavor：Cold in nature, sweet, slight bitter, there is the effect of clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, ease constipation, for treating lung heat cough Cough, the turbid Huang of phlegm is thick, chest impediment and cardialgia, acute mastitis, lung carbuncle, acute appendicitis swelling and pain etc. disease；

The bighead atractylodes rhizome, nature and flavor：It is bitter, sweet, warm-natured, have strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, it is antiabortive the effect of, for treating temper The few abdominal distension of weakness, spiritlessness and weakness, deficiency of food, big loose stool are thin, fluid retention stagnating in the interior, difficult urination, oedema, phlegmatic vertigo, warm numbness are ached, gas The diseases such as empty spontaneous perspiration, fetal irritability；

Radix rehmanniae recen, nature and flavor：It is sweet, bitter, cold in nature, there is the effect of heat-clearing, cool blood, enter ying blood, high fever for treating warm heat disease heat Coma, dry tongue are deep red；

Gynostemma pentaphylla, nature and flavor：It is bitter, cold, there is the effect of clearing heat and detoxicating, cough-relieving apophlegmatic, for treating chronic bronchitis, infectiousness Hepatitis, ephritis are scorching, gastroenteritis；

Poria cocos, nature and flavor：It is sweet, light, flat, have eliminating dampness and diuresis, strengthening the spleen and stomach, antitoxic heart-soothing and sedative the effect of, for treat difficult urination, The diseases such as oedema turgor, phlegm and retained fluid cough are inverse, vomiting, spleen eating less, diarrhea, palpitation and restlessness, insomnia forgetfulness, seminal emission gonorrhoea；

Radix Angelicae Sinensis, nature and flavor：Warm-natured, acrid-sweet flavor, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation the effect of, for treat the deficiency of blood, Sallow complexion, dizziness palpitaition, the deficiency of blood have the stagnant irregular menstruation of the stasis of blood, Amenorrhea, dysmenorrhoea, deficient cold type stomachache, coronary heart disease heart strand concurrently Bitterly, the disease such as arthralgia pain due to rheumatism, traumatic injury；

Gorgon fruit, nature and flavor：It is sweet, puckery, flat, there is the effect of reinforcing the kidney and controlling noctural emission, tonifying spleen stopping leak, for treating seminal emission, gonorrhoea, stranguria with turbid discharge, band Under, the disease such as urinary incontinence, stool diarrhea；

The root of herbaceous peony, nature and flavor：Bitter, acid, it is slightly cold, there is blood-nourishing and battalion, relieving spasm to stop pain, hold back the effect of high and level tone liver, for treating menstruation not The diseases such as tune, dysmenorrhea, uterine bleeding, spontaneous perspiration, night sweat, side of body rib epigastric pain, four limbs contraction pain, headache, dizziness；

Semen Cuscutae, nature and flavor：Xin Gan, put down, there is tonifying kidney and benefiting sperm, nourish the liver to improve visual acuity, consolidate the effect of tire stopping leak, for treating waist and knee acid Bitterly, seminal emission, impotence, premature ejaculation, infertility, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, fetal irritability, miscarriage, the disease such as diarrhea；

Loguat leaf, nature and flavor：Bitter, acrid, cold, it is nontoxic, there is the effect of removing heat from the lung to relieve cough, harmonizing stomach and lowering adverse Qi, quench the thirst, for treating lung heat phlegm Cough, the disease such as deficiency of Yin overstrain cough, hemoptysis, bleeding from five sense organs or subcutaneous tissue, stomach hot vomiting；

Potentilla discolor, nature and flavor：Sweet, slight bitter, put down, there is the effect of clearing heat and detoxicating, cooling blood and hemostasis, for treating enteritis, bacillary dysentery Disease, amoebic dysentery, haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, wound, carbuncle furuncle poison are controlled in leukorrhea, external application；

Wrinkled giant hyssop, nature and flavor：Acrid flavour, slightly warm in nature, there is the effect of driving away summer heat inducing diaphoresis, removing dampness to restore normal functioning of the stomach, for treating summertime flu, fever and chills head Bitterly, the disease such as chest gastral cavity ruffian, vomiting and diarrhea, the vomiting of pregnancy, nasosinusitis, hand, tinea pedis；

Hawthorn, nature and flavor：Sour sweet, tepor, it is nontoxic, there is digestion gathered food, change the effect of stagnant stasis of blood, for Therapeutic diet to be stagnant, gastral cavity abdomen is swollen Bitterly, dysentery, dysmenorrhea due to blood stasis, amenorrhoea, postpartum abdominal pain；The diseases such as lochiorrhagia；

Mulberries, nature and flavor：It is sweet, sour, cold, there is tonifying liver, kidney-nourishing, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., grow the effect of liquid, for treating liver-kidney Yin deficiency, quenching one's thirst, just Secret, mesh is dark, tinnitus, scrofula, articular instability；

Sealwort, nature and flavor：It is sweet, flat, have Yin nourishing and lung moistening, invigorate the spleen and benefit qi, Zishen fill fine the effect of, for treating deficiency of Yin overstrain cough, lung Cough caused by dryness is coughed, insufficiency of the spleen weak, few dry of food, quench one's thirst, deficiency of the kidney soreness and weakness of waist and knees, impotence and seminal emission, tinnitus mesh are dark, poliosis, physically weak win The diseases such as thin, wind favus disease；

Fructus meliae toosendan, nature and flavor：It is bitter, cold, it is slightly poisonous, have it is soothing the liver expel the heat-evil, promoting qi circulation and relieving pain, desinsection the effect of, for treat gastral cavity abdomen the side of body The diseases such as rib pain, hernia pain, abdominal pain due to enterositosis, favus of the scalp；

Radix cynanchi wilfordii, nature and flavor：It is sweet, slight bitter, flat, there is the effect of tonifying the liver and kidney, strengthening muscles and bones, for treat neurasthenia, impotence, Seminal emission, lumbocrural pain.

Medicine of the present invention is the principle based on traditional Chinese medical science diabetes, is recognized from the pathomechanism according to diabetes and pharmacological action For：With regard to diabetes, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good effect to above-mentioned disease.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned diabetes, the medicine prepared using the formula Thing good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail：

Embodiment 1：

A kind of pill medicine for treating diabetes, it is characterised in that each component and its mass parts of the medicine are than following institute Show：

Radix Astragali 280g, Fructus Corni 115g, Snakegourd Fruit 115g, bighead atractylodes rhizome 115g, radix rehmanniae recen 280g, gynostemma pentaphylla 10g, Poria cocos 200g, Radix Angelicae Sinensis 115g, Gorgon fruit 280g, root of herbaceous peony 115g, Semen Cuscutae 115g, loguat leaf 115g, potentilla discolor 115g, wrinkled giant hyssop 95g, hawthorn 95g, mulberries 230g, sealwort 118g, Fructus meliae toosendan 80g, Radix cynanchi wilfordii 230g, auxiliary material：Appropriate starch

Embodiment 2：

A kind of pill medicine for treating diabetes, it is characterised in that each component and its mass parts of the medicine are than following institute Show：

Radix Astragali 310g, Fructus Corni 130g, Snakegourd Fruit 130g, bighead atractylodes rhizome 130g, radix rehmanniae recen 310g, gynostemma pentaphylla 11g, Poria cocos 220g, Radix Angelicae Sinensis 130g, Gorgon fruit 310g, root of herbaceous peony 130g, Semen Cuscutae 130g, loguat leaf 130g, potentilla discolor 130g, wrinkled giant hyssop 105g, hawthorn 105g, mulberry Shen 260g, sealwort 130g, Fructus meliae toosendan 90g, Radix cynanchi wilfordii 260g, auxiliary material：Appropriate starch

Embodiment 3：

A kind of pill medicine for treating diabetes, it is characterised in that each component and its mass parts of the medicine are than following institute Show：

Radix Astragali 350g, Fructus Corni 150g, Snakegourd Fruit 160g, bighead atractylodes rhizome 160g, radix rehmanniae recen 350g, gynostemma pentaphylla 12g, Poria cocos 250g, Radix Angelicae Sinensis 160g, Gorgon fruit 350g, root of herbaceous peony 150g, Semen Cuscutae 150g, loguat leaf 150g, potentilla discolor 150g, wrinkled giant hyssop 120g, hawthorn 120g, mulberry Shen 300g, sealwort 150g, Fructus meliae toosendan 100g, Radix cynanchi wilfordii 300g, auxiliary material：Appropriate starch

Allusion quotation case

Through clinical conditions diabetic totally 1380, the age is 850 of more than 48 years old, only 530 for 48 years old with Under.Blood glucose is substantially delayed or controlled in 1380 patients 1170, effective 58, invalid 152.Total effective rate Up to 89%.

Claims (3)

1. a kind of pill medicine for treating diabetes, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：

90~350g of the Radix Astragali, 60~150g of Fructus Corni, 90~160g of Snakegourd Fruit, 80~160g of the bighead atractylodes rhizome, 100~350g of radix rehmanniae recen, strand 8~12g of stock indigo plant, 150~250g of Poria cocos, 80~160g of Radix Angelicae Sinensis, 150~350g of Gorgon fruit, 50~150g of the root of herbaceous peony, Semen Cuscutae 60~ 150g, 90~150g of loguat leaf, 50~150g of potentilla discolor, 60~120g of wrinkled giant hyssop, 30~120g of hawthorn, 150~300g of mulberries, Huang 100~150g of essence, 30~100g of Fructus meliae toosendan, 150~300g of Radix cynanchi wilfordii, auxiliary material：Appropriate starch.

2. it is according to claim 1 treatment diabetes pill medicine, it is characterised in that each component of the medicine and Its mass parts is than as follows：

100~310g of the Radix Astragali, 70~130g of Fructus Corni, 100~130g of Snakegourd Fruit, 90~130g of the bighead atractylodes rhizome, 115~310g of radix rehmanniae recen, 9~11g of gynostemma pentaphylla, 180~220g of Poria cocos, 90~130g of Radix Angelicae Sinensis, 180~310g of Gorgon fruit, 58~130g of the root of herbaceous peony, Semen Cuscutae 70 ~130g, 100~130g of loguat leaf, 58~130g of potentilla discolor, 70~105g of wrinkled giant hyssop, 38~105g of hawthorn, mulberries 180~ 260g, 115~130g of sealwort, 38~90g of Fructus meliae toosendan, 180~260g of Radix cynanchi wilfordii, auxiliary material：Appropriate starch.

3. the pill medicine of the treatment diabetes according to claim 1 to 2, it is characterised in that each group of the medicine Divide and its mass parts are than as follows：

Radix Astragali 280g, Fructus Corni 115g, Snakegourd Fruit 115g, bighead atractylodes rhizome 115g, radix rehmanniae recen 280g, gynostemma pentaphylla 10g, Poria cocos 200g, Radix Angelicae Sinensis 115g, Gorgon fruit 280g, root of herbaceous peony 115g, Semen Cuscutae 115g, loguat leaf 115g, potentilla discolor 115g, wrinkled giant hyssop 95g, hawthorn 95g, mulberries 230g, sealwort 118g, Fructus meliae toosendan 80g, Radix cynanchi wilfordii 230g, auxiliary material：Appropriate starch.