CN1075376C - 滴鼻剂 - Google Patents
滴鼻剂 Download PDFInfo
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- CN1075376C CN1075376C CN98118205A CN98118205A CN1075376C CN 1075376 C CN1075376 C CN 1075376C CN 98118205 A CN98118205 A CN 98118205A CN 98118205 A CN98118205 A CN 98118205A CN 1075376 C CN1075376 C CN 1075376C
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Abstract
本发明公开了一种滴鼻剂,在每10毫升生理盐水或蒸馏水中加入盐酸麻黄碱0.01-0.08克,喹诺酮类药物0.01-0.3克,肾上腺皮质激素药物0.005-0.02克,可在改善鼻通气的同时,进行抗菌、消炎、抗过敏,有效减轻鼻腔水肿,进而达到综合治愈之目的,经1000多例临床证明,总有效率达95%以上。
Description
本发明涉及到一种鼻炎用药,特别是一种滴鼻剂。
市场上有售多种用于治疗鼻炎的药物,如盐酸麻黄碱滴鼻液,可使血管收缩而改善鼻通气,但不能适症治疗,由于浓度达1%,而容易引起药物性鼻炎,就发明人所知目前还没有哪一种药物既可有效改善鼻通气,又具有广谱抗菌作用,同时又可抗过敏,减轻鼻腔水肿,并且副作用又少。
本发明的目的在于提供一种既可有效改善鼻通气,具有广谱抗菌作用,又抗过敏,减轻水肿,副作用不大的可综合适治新型滴鼻药。
本发明的目的是这样实现的:一种滴鼻剂,在每10毫升生理盐水或蒸馏水中含有盐酸麻黄碱0.01至0.08克,喹诺酮类药物0.01至0.3克,肾上腺皮质激素药物0.005至0.02克。
本发明所述喹诺酮类药物进一步来说为诺氟沙星或环丙沙星或氧氟沙星。
本发明肾上腺皮质激素类药物为氟美松。
本发明采用三种药物配伍,采用综合适治的办法从而达到了发明目的:由于采用了较少量的盐酸麻黄碱来收缩血管,从而可以达到既改善鼻通气,又温和持久,不易引发药物性鼻炎的作用;由于采用了喹诺酮类广普抗菌药物如诺氟沙星,可在收缩血管作用的同时对鼻腔内的细菌起到杀灭抑制作用;肾上腺皮质类药物具有抗过敏,减轻水肿的作用;本发明成份的适量有机组合,既改善了鼻腔通气,促进鼻窦引流,又减轻了鼻腔水肿,同时抗菌药物直接作用局部可有效杀灭细菌,治愈炎症,本发明经1000多例临床观察总有效率达95%以上。
以下通过实施例对本发明进行更为细致的描述:
实施例1:
在每10毫升生理盐水中加入盐酸麻黄碱0.02克,诺氟沙星0.08克,氟美松0.01克,溶解混匀,装入普通滴鼻剂瓶中即可,用法:每日滴鼻3次,每次3-5滴。可用于急、慢性化脓型上颌窦炎、急慢性鼻炎、过敏性鼻炎、感冒后鼻塞、流浓涕等。
实施例2:
在每10毫升蒸馏水中加入盐酸麻黄碱0.08克,环丙沙星或氧氟沙星0.1克,氟美松0.05克。
Claims (3)
1.一种滴鼻剂,其特征在于:在每10毫升生理盐水或蒸馏水中含有盐酸麻黄碱0.01至0.08克,喹诺酮类药物0.01-0.3克,肾上腺皮质激素药物0.005-0.02克。
2.根据权利要求1所述的滴鼻剂,其特征在于所述喹诺酮类药物为诺氧沙星或环丙沙星或氧氟沙星。
3.根据权利要求1或2所述的滴鼻剂,其特征在于肾上腺皮质激素类药物为氟美松。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN98118205A CN1075376C (zh) | 1998-08-30 | 1998-08-30 | 滴鼻剂 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN98118205A CN1075376C (zh) | 1998-08-30 | 1998-08-30 | 滴鼻剂 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1208617A CN1208617A (zh) | 1999-02-24 |
CN1075376C true CN1075376C (zh) | 2001-11-28 |
Family
ID=5225962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN98118205A Expired - Fee Related CN1075376C (zh) | 1998-08-30 | 1998-08-30 | 滴鼻剂 |
Country Status (1)
Country | Link |
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CN (1) | CN1075376C (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105168119A (zh) * | 2015-10-28 | 2015-12-23 | 周胜光 | 一种治疗鼻炎的复方滴鼻用凝胶制剂 |
-
1998
- 1998-08-30 CN CN98118205A patent/CN1075376C/zh not_active Expired - Fee Related
Non-Patent Citations (3)
Title |
---|
《新医学》"氧氟沙星、***滴耳液治疗慢性单纯型化脓性中耳" 1995.6.26 唐永元等;《药学实践杂志》,"鼻净滴剂 的制备及应用" 1996.5.14 陈伟成等 * |
《新医学》"氧氟沙星、***滴耳液治疗慢性单纯型化脓性中耳" 1995.6.26 唐永元等 * |
《药学实践杂志》,"鼻净滴剂 的制备及应用" 1996.5.14 陈伟成等 * |
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Publication number | Publication date |
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CN1208617A (zh) | 1999-02-24 |
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