CN107519329A - A kind of traditional Chinese medicine for oral administration for treating the cancer of the esophagus - Google Patents

A kind of traditional Chinese medicine for oral administration for treating the cancer of the esophagus Download PDF

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CN107519329A
CN107519329A CN201610441776.6A CN201610441776A CN107519329A CN 107519329 A CN107519329 A CN 107519329A CN 201610441776 A CN201610441776 A CN 201610441776A CN 107519329 A CN107519329 A CN 107519329A
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chinese medicine
cancer
esophagus
traditional chinese
oral administration
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邓泽潭
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/583—Snakes; Lizards, e.g. chameleons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487—Psoralea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/754—Evodia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)

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Abstract

The present invention discloses a kind of traditional Chinese medicine for oral administration for treating the cancer of the esophagus, is made up of following composition, the parts by weight of each component are：Mock-strawberry 20 40, bittersweet 20 40, black nightshade 20 40, romanet grape root 20 40, Sculellaria barbata 20 40, Inula britannica chinensis 15 30, thizoma curculiginis 15 30, psoralea corylifolia 15 30, evodia rutaecarpa 10 20, radix glehniae 15 30, stir-baked RADIX PAEONIAE ALBA 15 30, the fruit of Chinese wolfberry 15 30, house lizard 3 10.It is oral that internal dosage form is made.The Chinese medicine advantage of the present invention is that compatibility is reasonable, and convenient to take, curative effect is reliable, has no toxic side effect, and can effectively improve patient clinical symptom, improve the quality of living, and extends life cycle, and some patientss are visited 68 years still healthy livings and.

Description

A kind of traditional Chinese medicine for oral administration for treating the cancer of the esophagus
Technical field
The present invention relates to field of Chinese herbal, and in particular to a kind of Chinese medicine for treating the cancer of the esophagus.
Background technology
The cancer of the esophagus turns into a kind of most common malignant tumour of digestive system, clinical most common with dysphagia, and it is principal character that food, which has pain, after breastbone.Wherein over-65s gerontal patient accounting example has the trend of rising, and most of patients with terminal eating difficulties occurs, Hypoproteinemia occurs in long-term consumption, the symptom such as anaemia and transfer organ injury, has a strong impact on the quality of life of patient, reduces life cycle because of tumour growth.The effect of can also reaching radical cure without a kind of effective method both at home and abroad at present, and traditional Chinese medicine has the theoretical system of uniqueness, the method and curative effect for having uniqueness in terms of digestive system cancer is treated, can improve patient clinical symptom, improve the quality of living, and extends life cycle.
There are two for advanced esophageal carcinoma therapeutic purposes：First, extend life span, second, improving life quality.The traditional Chinese medical science thinks that the cancer of the esophagus belongs to the traditional Chinese medical science " dysphagic " category, and main pathogenesis is functional activity of QI being not smooth, deficient qi and blood, spleen is felt frustrated knot, body fluid must not defeated cloth, it is poly- and be phlegm, mental disorder hands over resistance oesophagus, then gradually give birth to dysphagic, long and hot and suffocating to injure yin-fluid, stomach-Yin virtual loss oesophagus is lost in making moist and not smooth, therefore food is swallowed and had some setbacks, when have pain.
During esophageal carcinoma therapy, while application removing toxic substances reducing phlegm and resolving masses, promoting blood circulation yin-nourishing open strongly fragrant, the yang-energy of human body should be paid attention to, the gradual temperatureization such as the cold sensation of the genitalia that tumour disease and evil is accumulated, aggregation, the stasis of blood are stagnant, be allowed to reduce, reduce, or even disappearance.
The chemotherapy of modern medicine, radiotherapy are all classified as " bitter cold " by we, gram scope for disappearing, sending an expedition against, it is long must the impairment of the spleen, the yang-energy of damage, making patient's body, natively insufficient " sun " becomes weaker, however growth encourage cancerous swelling develops.The cancer of the esophagus whether postoperative chemotherapy, radiotherapy, or person in middle and old age's property late period inoperable patient, the marrow of this traditional Chinese medical science of warming and invigorating kidney Yang should be paid attention in treatment.
The content of the invention
The invention discloses a kind of Chinese medicine for treating the cancer of the esophagus, the present invention has a warming and invigorating kidney Yang, invigorating the spleen yin-nourishing, removing toxic substances resolving sputum, and dissipating bind opens Yu Gongxiao.There is ideal clinical effectiveness to the cancer of esophagi patient of middle and advanced stage or post-surgical chemotherapy.
The technical solution adopted by the present invention is as follows.
A kind of traditional Chinese medicine for oral administration for treating the cancer of the esophagus, it is characterised in that be made up of following component, the parts by weight of each component are：Mock-strawberry 20-40, bittersweet 20-40, black nightshade 20-40, romanet grape root 20-40, Sculellaria barbata 20-40, Inula britannica chinensis 15-30, thizoma curculiginis 15-30, psoralea corylifolia 15-30, evodia rutaecarpa 10-20, radix glehniae 15-30, stir-baked RADIX PAEONIAE ALBA 15-30, fruit of Chinese wolfberry 15-30, house lizard 3-10.
The Chinese medicine of the described treatment cancer of the esophagus, is made up of following component, and the parts by weight of each component are：Mock-strawberry 30, bittersweet 30, black nightshade 30, romanet grape root 30, Sculellaria barbata 20, Inula britannica chinensis 20, thizoma curculiginis 20, psoralea corylifolia 15, evodia rutaecarpa 15, radix glehniae 20, stir-baked RADIX PAEONIAE ALBA 20, the fruit of Chinese wolfberry 20, house lizard 6.
Usage and dosage.The medicine of the present invention can use the conventional method of Chinese drugs agentia to be prepared into various conventional internal dosage forms.Such as these raw materials are smashed and is well mixed powder processed and takes after mixing it with water or be made other balls, honey, capsule peroral dosage form, can also be directly prepared into decoction oral, daily 1 dose, water is decocted and takes for 2 to 3 times；It is 12-15 grams of crude drug powder that daily dose during pill, which is made, 30 days as one therapeutic course, the general 1-4 course for the treatment of.
The theory of traditional Chinese medical science and medication foundation of the present invention.
The traditional Chinese medical science thinks cancer of the esophagus category " dysphagic " category.Zhang Jingyue is so-called：" a dysphagic card, must be pondered over sorrow, is overworked for a very long period strongly fragrant or is dissipated in wine and sex, then essence and blood dries up impairment of yin that impairment of yin forms ..., and gas is not all right.Then dysphagia is in upper, essence and blood dry up then constipation disease under ".It can be seen that the pathogenic QI in the body knot, phlegm are strongly fragrant, impairment of yin, malicious heresy are this sick pathomechanisms.
The medication foundation of the present invention：Mock-strawberry clearing heat and cooling blood, detoxify and dissipate the stasis of blood；Bittersweet clearing heat, releasing toxin, removing swelling；Black nightshade removing toxic substances activating blood circulation and reducing swelling；Romanet grape root disperse accumulations is detoxified；Sculellaria barbata removing toxic substances eliminating stasis to subdue swelling；Inula britannica chinensis lowering the adverse-rising QI to resolve phlegm stopping nausea and vomiting by lowering the adverse flow of QI；Psoralea corylifolia, thizoma curculiginis warming kidney and enhancing yang；Evodia rutaecarpa eliminating cold to stop pain is soothing the liver, and drop is inverse；Cloudy benefiting essence-blood is held back in radix glehniae, the root of herbaceous peony, fruit of Chinese wolfberry blood-nourishing；House lizard detoxicating and resolving a mass.All medicines share, warming and invigorating kidney Yang, invigorating the spleen yin-nourishing, removing toxic substances resolving sputum, the work(of blood circulation promoting and dispersing pathogen accumulation are played altogether.For improving clinical symptoms, improving the quality of living has significant clinical efficacy, it is often more important that can extend life cycle.
Modern pharmacology proves that above medicine can effectively suppress the growth of cancerous swelling, intervenes tumour cell metabolism, humoral immunity is reconciled, strengthens natural killer cell activity, has significant diminution to act on to cancerous swelling block, the prior immunologic function that can improve human body, extend life cycle.
Full side is made a general survey of, compatibility is rigorous, monarch, minister, helps, makes clearly demarcated, the interpretation of the cause, onset and process of an illness for the cancer of the esophagus of hitting, having fully demonstrated the principle of reatment of " righting Eradicates is evil ".
Embodiment
Below by way of specific embodiment, the invention will be further described.
Embodiment 1：Take mock-strawberry 20-40, bittersweet 20-40, black nightshade 20-40, romanet grape root 20-40, Sculellaria barbata 20-40, Inula britannica chinensis 15-30, thizoma curculiginis 15-30, psoralea corylifolia 15-30, evodia rutaecarpa 10-20, radix glehniae 15-30, stir-baked RADIX PAEONIAE ALBA 15-30, fruit of Chinese wolfberry 15-30, house lizard 3-10.By above-mentioned Chinese medicine material cleaning, drying and then grind, in powder, 100-200 mesh sieves of looking over so as to check, proper honey is added after sterilization pill or tablet is made, every medicine contains 0.5 gram of crude drug powder, even served the 1-4 course for the treatment of.
Embodiment 2：Take mock-strawberry 30, bittersweet 30, black nightshade 30, romanet grape root 30, Sculellaria barbata 20, Inula britannica chinensis 20, thizoma curculiginis 20, psoralea corylifolia 15, evodia rutaecarpa 15, radix glehniae 20, stir-baked RADIX PAEONIAE ALBA 20, the fruit of Chinese wolfberry 20, house lizard 6.By above-mentioned Chinese medicine material cleaning, drying and then grind, in powder, 100-200 mesh sieves of looking over so as to check, proper honey is added after sterilization pill or tablet is made, every medicine contains 0.5 gram of crude drug powder, the 1-4 course for the treatment of is used in conjunction.
Treatment results：The cancer of the esophagus 18, man 13, female 5, age 65-85 year, 3 year life cycle 95%, 4 year life cycle 80%, 5 year life cycle 60%, 6 year life cycle 55%, 8 year life cycle 35% are treated with the medicine.
In the formula of example 2, compatibility is reasonable, curative for effect, and full side has warming and invigorating kidney Yang, and invigorating the spleen yin-nourishing, resolving sputum of detoxifying, dissipating bind opens Yu Zuoyong, is to treat this sick key point so as to block the pathology link of cancer of the esophagus advolution.
Model case.
Case 1：Ma, man, 78 years old, Wuhe County Liu market town, occur food potruncus sense of obstruction in June, 2013, check as the cancer of the esophagus, in Bangbu, radiotherapy is done 3 months by tumour hospital, and face Huang is become thin, poor appetite, due to getting old and weak, it is reluctant to go radiotherapy again, changes and take Chinese medicine of the present invention, it even served 3 months, appetite is good, and body weight increases, in high spirits.Visit 2 years, now remain to do a little slight housework.
Case 2：Zhang, man, 81 years old, Huaibei City retired worker, suffered from the cancer of the esophagus in 2013, and due to older, expectant treatment is suggested by hospital.Take Chinese medicine of the present invention 4 months, clinical symptoms are obviously improved, and are now visited still alive.
Case 3：Zheng, female, 70 years old, Wuhe County area just outside a city gate town peasant, in June, 2012, breastbone secret anguish, swallowed eating difficulties, showed in Bang Yifu institutes barium piece of ingesting, esophagus lower end cancer.Due to advanced in age, hospital and family are disagreed perform an operation per capita, and here is come in July, 2012 and requires to take Chinese medicine of the present invention, even served 3 months, diet takes a turn for the better, and increased weight is still good so far.

Claims (2)

1. a kind of traditional Chinese medicine for oral administration for treating the cancer of the esophagus, it is characterised in that be made up of following component, the parts by weight of each component are：Mock-strawberry 20-40, bittersweet 20-40, black nightshade 20-40, romanet grape root 20-40, Sculellaria barbata 20-40, Inula britannica chinensis 15-30, thizoma curculiginis 15-30, psoralea corylifolia 15-30, evodia rutaecarpa 10-20, radix glehniae 15-30, stir-baked RADIX PAEONIAE ALBA 15-30, fruit of Chinese wolfberry 15-30, house lizard 3-10.
2. the traditional Chinese medicine for oral administration of the treatment cancer of the esophagus according to claim 1, because row component forms, the parts by weight of each component are its feature：Mock-strawberry 30, bittersweet 30, black nightshade 30, romanet grape root 30, Sculellaria barbata 20, Inula britannica chinensis 20, thizoma curculiginis 20, psoralea corylifolia 15, evodia rutaecarpa 15, radix glehniae 20, stir-baked RADIX PAEONIAE ALBA 20, the fruit of Chinese wolfberry 20, house lizard 6.
CN201610441776.6A 2016-06-20 2016-06-20 A kind of traditional Chinese medicine for oral administration for treating the cancer of the esophagus Pending CN107519329A (en)

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Citations (4)

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CN1562208A (en) * 2004-04-07 2005-01-12 龙万春 Medication for treating malignant tumor and preparation method
CN104248741A (en) * 2013-06-26 2014-12-31 天津中新药业集团股份有限公司隆顺榕制药厂 Traditional Chinese medicinal composition for treating cancers, and preparation method thereof
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Application publication date: 20171229