CN107519119A

CN107519119A - A kind of snake gall anti-acne essence cream and preparation method thereof

Info

Publication number: CN107519119A
Application number: CN201710774871.2A
Authority: CN
Inventors: 黄小燕; 韦鑫
Original assignee: Guangxi Xiaoyan Snake Industry Co Ltd
Current assignee: Guangxi Xiaoyan Snake Industry Co Ltd
Priority date: 2017-08-31
Filing date: 2017-08-31
Publication date: 2017-12-29

Abstract

The present invention relates to a kind of snake gall anti-acne essence cream and preparation method thereof, its active ingredient is to be prepared from the following raw materials in parts by weight：0.1~0.6 part of propyl p-hydroxybenzoate, 0.1~0.6 part of Methyl p-hydroxybenzoate, 1618 0.3~0.8 part of alcohol, A165 is 1~6 part, GP 200 is 1~8 part, IPM2~10 part, 2~8 parts of saualane, 200 2~8 parts of DC, molten 0.4~1 part of the VE of oil, 0.04~0.12 part of borneol, 2~8 parts of 26# white oils, EDTA2Na0.04~0.2 part, 0.2~1 part of allantoin, 940 0.2~1 part of card ripple, 2~8 parts of niacinamide PC, 6~16 parts of glycerine, 2~14 parts of propane diols, the raw materials such as 70~80 parts of deionized water are made.The progress that the present invention can enhance metabolism, activating skin cells, for skin nutrition；The features such as having no side effect.

Description

A kind of snake gall anti-acne essence cream and preparation method thereof

Technical field

The present invention relates to a kind of acne eliminating cream field, and in particular to a kind of snake gall anti-acne essence cream and preparation method thereof.

Background technology

The generation of acne mainly blocks with hypersteatosis, pilosebaceous duct, bacterium infection and inflammatory reaction etc. Factor is closely related.Adolesce the rapid rise of level of androgen particularly testosterone in descendant's body, promotes sebaceous glands development And produce a large amount of sebums.The dyskeratosis of pilosebaceous duct causes catheter blockage simultaneously, dyssebacia, forms cutin Bolt is micro mist thorn.Multiple-microorganism especially propionibacterium acnes amount reproduction, lipase caused by propionibacterium acnes in hair follicle Sebum generation free fatty, while chemotactic inflammatory cell and medium are decomposed, finally induces and aggravates inflammatory reaction.Such as the youth Acne, acne, dark sore are medically referred to as acne, are that a kind of common sebaceous glands is chronic.

The reason for triggering small pox also has following several：1st, 3male hormone secretion is excessive；2nd, fat secretion is excessive, hypersecretion Sebum and sweat, dust, germ, the obstruction sebaceous glands mouth such as acarid do not removed in time；3rd, local inflammation；4th, bacterium infection, Cross-infection, the effect of pathogenic microorganism-Propiobacterium；5th, immune antiboidy acts on；6th, inherent cause；7th, microelement deficiencies, Cause hyperkeratinization；8th, the contact of mineral oils, such as the use of iodide, bromide；9th, animal tallow and polysaccharide food are eaten more, The gastrointestinal disorders such as indigestion or constipation；10th, psychological condition is not gentle, nervous, irritable, sleep insufficiency；11st, water and soil Disobedience, warm etc..

Anti-acne is that the process of whelk is eliminated with medical technology or method, is mainly drawn by anaerobic acne Propionibacterium A kind of skin disease of the chronic pilosebaceous inflammations risen.It is caused by many reasons, and has a strong impact on that people's is attractive in appearance, even Life.Anti-acne be it is necessary, it is even more important.

Through retrieving the Chinese patent literature about anti-acne, it is as follows to enumerate some：

1st, Chinese patent<Application number>201610495491.0<Denomination of invention>A kind of Pimple removing scream<Applicant>Cao Meilan<Address >236514 Ren Zhai townshiies Zhang Xu administrative villages, Fuyang City Jieshou City, Anhui Province 28<Inventor>Chen Fufeng, Cao Meilan<Summary>It is a kind of Pimple removing scream, by weight, including following raw material：Beardie mucus 4~6, Chinese medical extract 1~2, glycerine 5~7, vaseline 3~ 5th, olive oil 0.5~0.8, hyaluronic acid 1.5~2.5, cinnamyl alcohol 1~1.5, xanthans 0.1~0.2, stearine 3.5 ~5.5, Phenoxyethanol 0.1~0.2, water 15~20；The Chinese medical extract is with honeysuckle, chrysanthemum, dandelion, the root of herbaceous peony and sweet Grass is raw material, through obtained by water extraction, concentration.

2nd, Chinese patent<Application number>201611062487.1<Denomination of invention>A kind of anti-acne moisturiser<Applicant>Qingdao Self-employed tree cultivator's industry Science and Technology Development Co., Ltd. in source<Address>266000 Qingdao of Shandong province Laixi City Yuan Shang towns Yuan Shang villages 88<Invention People>Liu Shuyuan<Summary>The invention discloses a kind of anti-acne moisturiser, by following mass fraction formula components group：Coix seed 4-6 Part, -5 parts of phosphatidase 4, chrysanthemum 6-8 parts, natural glycerin 25-35 parts, tuber of dwarf lilyturf 5-7 part, stearyl alcohol 2-6 parts, saualane 2-4 parts, giant knotweed 6-8 parts, water 200-300 parts.

3rd, Chinese patent<Application number> 201310725257.9<Denomination of invention>A kind of Pimple removing scream<Applicant>Suzhou Nation of city is into Electronic Science and Technology Co., Ltd.<Address>215212 Suzhou City of Jiangsu Province Wujiang Li Li towns Huayang East Road 8<Inventor> Chen Hangang<Summary>A kind of Pimple removing scream is disclosed, it is made up of the raw material of following weight：2~8 parts of vaseline, 1~3 part of vitamin e acetate, 0.1~1 part of methyl hydroxybenzoate, 1~2 part of vitamin C, 2~4 parts of kuh-seng powder, thymol 2~ 5 parts, 1~3 part of lavender, 0. 5~1.5 parts of emulsifying agent, 80~90 parts of water.It is preferred that it is made up of the raw material of following weight： 6 parts of vaseline, 2 parts of vitamin e acetate, 0.6 part of methyl hydroxybenzoate, 1.5 parts of vitamin C, 3 parts of kuh-seng powder, thymol 3 Part, 2 parts of lavender, 1 part of emulsifying agent, 85 parts of water.The emulsifying agent is DTAC.

4th, Chinese patent<Application number>201510841477.7<Denomination of invention>A kind of acne eliminating cream formula and its making side< Applicant>Hu Shuhui<Address>450000 attached No. 3 of Zhengzhou City Henan Provinces Zhongyuan District Long Hai West Roads 169<Inventor>Hair is not announced A person of good sense<Summary>A kind of acne eliminating cream formula and preparation method are disclosed, making raw material includes the combined things of A, the combined things of B, C phases Composition and the combined things of D；The combined things of A include aqueous solvent, caprylic/capric triglyceride, cetostearyl alcohol, stearic acid Butyl ester, PEG-100 stearates, Laurocapram, PEG20 distearates, methyl hydroxybenzoate and Nipasol；Its preparation method For step 1, the combined thing agitating and heating dissolvings of A；Step 2, the combined thing agitating and heating dissolvings of B；Step 3, the combined things of A Mixed with the combined things of B；Step 4, C are added in mixed A phases and B phase mixtures；Step 5, D are added to mixed above Stir and cool down in thing；Step 6, the filling storage of inspection by sampling.

5th, Chinese patent<Application number>201310480771.0<Denomination of invention>A kind of anti-acne antiallergic cream and preparation method <Applicant>Gua Fen bio tech ltd of Shenzhen<Address>518100 Baoan District, Shenzhen City, Guangdong Province, two tunnels 20 of foundation Eight area west side dormitories A No. 201<Inventor>Deng Shuisheng, Deng Jinhui<Summary>A kind of anti-acne antiallergic cream is disclosed, it includes Stereth 1, stereth -20, stearine and PEG-100 stearates, stearic acid, cetostearyl alcohol, Aloe, dimethyl silicone polymer, nutmeg isopropyl propionate, to benzene hydroxypropanol, to benzene hydroxy methyl, fertility sweet smell, azone, red do not have Medicine alcohol, glycerine, xanthans, EDTA-2Na, propane diols, ethanol, menthol, salicylic acid, phellodendron extract, Baical Skullcap root P.E, Neem leaf extract, elm spiraea chrysanthemum extract, royal jelly extract, Folium Aloe extract, tea oil, sodium hydroxide mixing Form.

From the document retrieved we it can be appreciated that product obtained by these formula for dispelling pox, effect is not good enough, how to have Effect improves anti-acne effect, protects skin, is still the main direction of daily chemical product research so far.

The content of the invention

The purpose of the present invention is the defects of overcoming in the prior art, and provides a kind of addition natural disinfection composition, promotes new The progress of old metabolism, activating skin cells, for skin nutrition, protects skin not corroded by bacterium；Can also antiallergic cream can dispel powder Thorn, promote facial blood circulation and Skin Cell regeneration, improve skin-tolerant, reduce or eliminate the allergic reaction of skin；Carry The high allergy tolerance of skin, safely and effectively snake gall anti-acne essence cream and preparation method thereof.

In order to realize the purpose of foregoing invention, the technical scheme taken is：

A kind of snake gall anti-acne essence cream, its active ingredient are to be prepared from the following raw materials in parts by weight：

0.1~0.6 part of propyl p-hydroxybenzoate

0.1~0.6 part of Methyl p-hydroxybenzoate

1618 0.3~0.8 part of alcohol

1~6 part of A165

1~4 part of GP-200

2~10 parts of IPM

2~8 parts of saualane

2~8 parts of DC-200

Molten 0.4~1 part of the VE of oil

0.04~0.12 part of borneol

2~8 parts of 26# white oils

0.04~0.2 part of EDTA2Na

0.2~1 part of allantoin

940 0.2~1 part of card ripple

2~8 parts of niacinamide

6~16 parts of glycerine

2~14 parts of propane diols

70~80 parts of deionized water

0.2~0.5 part of TEA

0.3~0.8 part of PE9010

Compound 0.6~2 part of the anti-acne factor

0.2~2 part of snake gall extract.

Above-described preparation method includes following steps：

（1）Propyl p-hydroxybenzoate, Methyl p-hydroxybenzoate, 1618 alcohol, A165, GP-200, IPM, saualane, DC-200 and the molten VE of oil are thrown Enter clean oil cauldron to dissolve by heating to 76~82 DEG C of degree；Add borneol and 26# white oils dissolve, homogeneous 2~3 minutes, obtain material Mixture A, constant temperature are standby；

（2）EDTA2Na, allantoin, card ripple 940, niacinamide, glycerine, propane diols and deionized water are put into clean emulsification pot 85~90 DEG C are heated with stirring to, homogeneous is completely dissolved no particle in 2~3 minutes to card ripple 940, obtains mixtures of materials B, standby；

（3）Mixtures of materials A and mixtures of materials B is pumped into emulsification pot and stirred 4~6 minutes, homogeneous 3~5 minutes, constant temperature 20 Defoam within~24 minutes, obtain mixtures of materials C, it is standby；

（4）Mixtures of materials C is cooled, is down to 68~72 DEG C, TEA is added and stirs, homogeneous 3~4 minutes, obtains thing Material mixture D, constant temperature are standby；

（5）Mixtures of materials D is cooled, is down to 38~42 DEG C, PE9010, the compound anti-acne factor and snake gall is added and carries Take thing to stir, homogeneous 3~4 minutes, coagulate frost, discharged after qualified to version, pack or bottling, produce snake gall anti-acne essence cream.

The loss water of each step is pressed per step material gross weight in made as described above method 2% adds.

The preparation method of snake gall extract solution described above is：Snake gall after drying in the shade is put in 1~2 point of microwave in micro-wave oven Clock, taking-up are soaked in 50~60 DEG C of hot water, and constant temperature soaks 15~20 minutes, takes out the snake gall of water swelling, is put in and has disappeared Punctured in the collector of poison and by snake gall, collect liquid；By the liquid it is purified, concentration, produce snake gall extract solution.

Snake gall described above is cobra snake gall, zaocys dhumnade snake gall, Bungarus multicinctus snake gall, pallas pit viper snake gall, banked krait snake gall, eye It is a kind of in mirror boa snake gall or adder snake gall.

Propylben, also known as Buddhist nun moor rope, 4-HBA propyl ester, to Para Hydroxy Benzoic Acid propyl ester.It is a kind of white Crystallization or powdery, it is micro- to have special odor, it is a kind of food additives and organic synthesis raw material.For sterilization antiseptic；When with Buddhist nun Moor tortoise beetle ester it is mixed when, moreover it is possible to kill pseudomonas aeruginosa (Pseudomonas aeruginosa)。

Methyl hydroxybenzoate, be called methyl p-hydroxybenzoate, white crystalline powder or colourless crystallization, be soluble in alcohol, ether and Acetone, it is atomic to be dissolved in water, 270-280 DEG C of boiling point.Organic synthesis, food, cosmetics, the sterilization antiseptic of medicine are mainly used as, Also serve as in feed anticorrosion agent.

Fatty alcohol is amber thick liquid, has the performance such as wetting, washing, antistatic, is good foam stabiliser, Also have softness, with other surfaces activating agent with the use of having the function that good synergy, scattered dirt particles, toxicity and Soap is suitable, small to skin irritation.Main application：This product is light rear profile liquid detergent, shampoo, cleaning agent, Liquid Fertilizer The indispensable composition of the various neutral detergents used for cosmetic such as soap, shaving cream, facial agent and shampoo, also acts as cream The emulsion stabilizer of creme product.

A165 is a kind of emulsifying agent, is called self-emulsifying monoglyceride, is a kind of high-quality and efficient nonionic oil-water emulsifiers, It has good anti-electrolyte capability, extensive compatibility and excellent stable emulsifying performance, in profit system, utilizes Its existing hydrophily has oil loving feature again, at low concentrations, product is formed uniform emulsification system, can be used as cream Frost, the main or coemulsifier of emulsion.The supply of material Business Name be：Guangzhou Yi Jin bio tech ltd；CompanyAddress：Extensively Dong Sheng Guangzhous districts under city administration Baiyun District summer thatch generation contains exhibition center B1-5；Net purchase network address is：

。

GP-200 is cetostearyl alcohol, PEG-20 stearates；A kind of white chips shape solid, product category for it is non-from Sub- emulsifying wax, GP 200 are a kind of non-ionic emulsifying wax from thickening type, HLB value:≈ 8.0, there is unique micro-crystal type knot Structure, cosmetics and hair care product satisfactory emulsification agent can be used as, it is remarkable emulsifying agent.Either emulsion or thicker lotion, it is all There is splendid stability.Energy acid-fast alkali-proof, can be emulsified to polarity and nonpolar grease, and it is thin to emulsify lotion outward appearance out It is greasy it is bright, auxiliary malleability is good, there is abrupt release feature, easily smear, assign product comfortably smear very much characteristic, effectively play effect Composition absorbs.It can be used alone or can be transferred to 3 ~ 13 as assistant for emulsifying agent, the pH value of product, be adapted to apply to all kinds of acid, alkalescence Cosmetics ointment.Nonionic emulsifier, can compound anion or cationic emulsifier uses, suitable for resistance to ionic system. Product safety, almost without any excitant.Its optimum point is to show chemical inertness to the additive of cosmetics and pharmaceuticals And highly compatible.Can commercially it purchase, Business Name of supplying：Guangzhou An Pin Chemical Co., Ltd.s, CompanyAddress：It is Chinese wide Eastern Nansha Area, Guangzhou area Feng Ze East Roads 106；Net purchase network address is：

IPM is isopropyl myristate, is widely used in cosmetics, can play a part of moisturizing and skin care, skin It is preferable to the absorbability of this product, it can effectively be contacted with hair follicle in cortex, penetrate into cortex depths, and by the activearm in cosmetics Divide and bring into, give full play to the effect of active ingredient.As cosmetic solvents and skin moisturizer, bleeding agent.

Saualane（Squalane）Molecular formula C30H₆₂It is the hydrogenated system of the squalene extracted from hydrogenated hydro carbons grease A kind of squalene extracting of excellent performance, therefore also known as eepwater shark liver oil.Scientific research finds that saualane is that rare chemistry is steady Qualitative height, the splendid animal fat of use feeling, there is preferable compatibility to skin, will not cause allergy and stimulation, and can accelerate Other active components are permeated into skin in formula；With relatively low polarity and medium spreadability, and it is pure, colourless, be no different Taste；It may also suppress the growth of mould.Also have and strengthen maintenance epidermis, be effectively formed natural diaphragm, help between skin and sebum Balance；For closest to a kind of lipid of human sebaceous, affinity is strong, can be combined together with the sebum film of mankind itself, Skin surface forms one layer of natural barrier；The peroxidating of skin lipid can also be suppressed, can effectively infiltrate through skin, and promote skin The propagation of skin basal cell, to delay skin aging, improving and eliminating chloasma has obvious physiologic effect；Skin can also be made Pore is opened, and promotes blood microcirculation, promotes the metabolism of cell, and damaged cell is repaired in help.

The molten VE of oil is fat soluble vitamin E, and vitamin E is also known as tocopherol, is a kind of oil-soluble natural materials, to flesh Skin is good nutrition moisturizing agent, is made an addition in skin care products, can avoid the oxidation of becoming sour of grease, stabilizes grease.It is present in more In plant tissue, it is D types that natural tocopherol, which has, and artificial synthesized for DL types.Vitamin E grease, in oxygen free condition Under to thermostabilization.Free vitamin E and its ester is all highly soluble in grease and most of organic solvents, not soluble in water, has anti- The effect of oxidant.It can protect and be easy to oxidation material damage inside and outside human body, improve protein, fat and carbohydrate Metabolism, keep elasticity of skin.Prevent or delay grease therein to become sour, protect lipid and protein in cell membrane, make its hair The effect combined with moisture is waved, therefore with the function of keeping moisture, moist skin.Skin aging is old mainly due to organism The external factor such as the internal factor of change and illumination, vitamin E is added in sunscreen productses can prevent ultraviolet and pollution air pair The injury of skin, promote the metabolism of skin, prevent pigment deposition, improve skin elasticity, skin care.In shampoo and hair care Vitamin E is added in element, can be deposited on or penetrate into pass hair, can prevent from polluting the injury of air and strong light to hair, keep hair Moisten, it is pitch-black beautiful, meanwhile, aminated compounds therein can be prevented to be contaminated.

Borneol, other titles：Borneol, kapur, brain, borneol, piece brain, borneol brain, plum blossom brain, natural borneol, Lao Mei Piece, Borneolum.Main component：This product is the crystallization obtained from the resin and volatile oil of kapur, is almost pure dextrorotation dragon Brain.Contain a variety of ter penoidses in the resin and volatile oil of kapur.In addition to borneol, still containing Humuleno, beta-elemene, carypohyllene Etc. sequiterpene, the triterpene such as oleanolic acid, alphitolic acid, asiatic acid, dipterocarpol, dryobalanone, erythrodiol Compound.

26# white oils are cosmetic grade white oil, and one kind in mineral oil, be using hydrogenating materials after deep refining Arrive.Suitable for cosmetic industry, can make the ointment such as hair-cream, hair oil, lipstick, face oil, skin care oil, sunblock lotion, baby oil, toilet cream and The base oil of softening agent.Cosmetic grade white oil can be used as antistatic additive, emollients, solvent, solvent, hydrocarbon, can increase wet Moisture feeling, but can not directly improve and dry impaired skin.Whether injuring skin for mineral oil, opinions vary, but confirmable It is that impure meeting causes allergy and causes acne, and should avoid using in injury or sensitiveness skin quality person.Due to its color and luster And characteristic, it is usually used in white cream drug or skin care products.

EDTA2Na is disodium ethylene diamine tetraacetate, for tasteless odorless or micro- salty white or creamy white crystals or graininess Powder；For metal antidote, complexing agent, antioxidant synergist, stabilizer and softening agent etc.；It is a kind of good compounding ingredient, it There are six coordination atoms, the complex of formation is called chelate, and EDTA is often used in complexometric titration, usually determines metal The content of ion；As cosmetic additive agent.

Allantoin sterling is a kind of nontoxic, tasteless and nonirritant, without hypersensitive white crystal, and crystallization is single rib in water Cylinder or colorless crystalline powder.In terms of medicine：Allantoin, which has, promotes cell growth, accelerates wound healing, cutin-softening The physiological functions such as albumen, it is the good consolidant and antiulcer agents of skin trauma.Can be used as alleviating and treat xerodermia, Scaling skin illness, skin ulcer, digestive tract ulcer and inflammation, there is preferable treatment to osteomyelitis, diabetes, hepatic sclerosis, acne Effect.In terms of cosmetics：Because allantoin is a kind of amphoteric compound, many kinds of substance can be combined and form double salt, there is lucifuge, kill Bacterium anti-corrosion, analgesic, antioxidation, skin can be made to keep moisture content, moisten and soft, be that the special efficacy of the cosmetics such as cosmetology adds Add agent, be widely used in freckle cream, anti-acne toner, shampoo, perfumed soap, toothpaste, shaving lotion, conditioner, astringent, anti-sweat deodorization lotion Deng additive.The cosmetics of addition allantoin have protective tissue, it is hydrophilic, absorb water and prevent moisture from the effect such as distributing；Addition Hair-cream, hair cream, the shampoo of allantoin, have protective effect to hair, can make hair not bifurcated, constantly hair；Add allantoin Skin, lip can be made soft for lipstick, face cream and high resilience, and has the gloss of beauty.Allantoin promotion organization grows, and cell is new Old metabolism, cutin-softening layer albumen.

Card ripple 940 is a kind of high molecular chemical substance, has very strong swellability and subacidity, because to skin safe It is nontoxic, and excellent stability, so in being widely used the Essence and latex that make cosmetics.

Card ripple 940, English name：Carbomer 940, CAS NO. 9003-01-4, character are white fluffy powder；Have Characteristic is micro- smelly；Hygroscopicity is very strong.Also referred to as Acritamer 940, it is that the acrylic acid for being crosslinked to obtain with acrylic acid with pentaerythrite etc. is handed over Join resin, carbomer is present in water with acid form, in water and polar organic solvent（Such as ethanol, glycerine etc.）It is easily molten It is swollen.It contains the acrylate copolymer of polyalkenyl polyether crosslinking, contains 56% -68% hydroxy-acid group in molecule, makes these resins be in Faintly acid, although being weaker than acetic acid, it is easy to and inorganic base and organic bases reaction generation salt.It due to have swellability and Faintly acid, it is a very important rheology control agent, the carbomer after neutralization is outstanding gel-type vehicle, has thickening, hangs The critical nature such as floating, technique is simple, and stability is good, is widely used in emulsion, cream, gel.Card ripple 940 has：Short rheology Property, high viscosity, high clarity, the features such as low resistance to ionic and endurance of cutting, its effect in the product is mainly reflected in three Aspect：Thickening, suspend and emulsify.Card ripple 940 just can produce big viscosity (conventional amount used 0.25- in the case where content is very low 0.5%).Carbomer can be used as excellent suspending agent, make insoluble component permanent suspension in system；Also emulsification can be used as Agent, emulsification and stabilization are played in oil/water phase.In addition it he be also superior cosmetics residuite and pharmaceutic adjuvant base Matter, and maximally effective water-soluble thickener.

Niacinamide is a kind of water soluble vitamin and is a member in vitamin B complex.Nicotinic acid can be in vivo converted For niacinamide.In cell, nicotinic acid be used to synthesize NADH（NAD）With two nucleoside of nicotinamide adenine Acid phosphoric acid（NADP）, and the approach of transition pathway and nicotinic acid is closely similar for niacinamide.NAD+ and NADP+ is a variety of enzymes The coenzyme of enzymatic oxidation reduction reaction.Niacinamide is water soluble vitamin.It can be distributed widely in vivo, excessive portion is rapidly with metabolism Product or original shape are from urine ejection.Niacinamide is the part of cozymase and codehydrogenase Ⅱ, is played in biological oxidation respiratory chain and passs hydrogen Effect, can promote biological oxidation process and tissue metabolism, to maintain normal structure（Particularly skin, alimentary canal and god Through system）Integrality play an important roll.In addition, still there is preventing and treating heart block, improve sinus node function and resistance to rapid Type Experimental Arrhythmia acts on, and can significantly improve as the decreased heart rate caused by Verapamil and atrioventricular block.

Glycerine, it is glycerine, colourless, odorless, sweet, outward appearance is in clear and bright viscous liquid state, and the energy moisture absorption, moisturizing, is that one kind has Machine thing.Glycerine, it is glycerine, colourless, odorless, sweet, outward appearance is in clear and bright viscous liquid state, the energy moisture absorption, moisturizing, is a kind of organic Thing.Glycerine is a kind of colourless, odorless, sweet thick liquid.The chemical constitution of glycerine and carbohydrate are entirely different, thus It is not belonging to same class material.Winter people are often put on the skin in the aerial skin surface of the exposure such as hand and face with glycerine, Malaysia this Literary glycerine, skin can be made to keep soft, high resilience, do not damaged and dried by dust, weather etc., playing prevents skin frostbite Effect.The moisture in tissue can be increased due to glycerine, it is possible to increase the fortune of human body under high-heat environment Kinetic force.In the wild, glycerine acts not only as Energy supply material, meets human body needs.Starting mix is also used as, method is： 5 ~ 10 grams of the potassium permanganate solid Indonesia spring gold glycerine on heap under combustible, then glycerine is poured on potassium permanganate, about half point Clock just has flare to emerge.Because glycerine is sticky, it is possible to the flammable organic solvent dilution such as available absolute ethyl alcohol in advance, but solvent It is unsuitable excessive.Main application：For GC stationary liquid and organic synthesis, it is also possible to make solvent, gas gauge and hydraulic press and subtract Shake agent, softening agent, antifreezing agent, antibiotic fermentation nutritional agents, drier etc..

Propane diols is 1,2-PD, is a kind of chemical reagent, with water, ethanol and a variety of immiscible organic solvents, its chemistry Formula is C3H8O2.It is colourless viscous liquid under normality, it is almost tasteless, carefully hear micro- sweet tea.Propane diols can be used as unsaturated polyester resin Raw material can coordinate in cosmetics with glycerine or sorbierite and be used as wetting agent.

TEA is triethylamine, is a kind of colourless oil liquid, has strong ammonia smelly.There is strong impulse to respiratory tract, suck After pulmonary edema can be caused even dead.Oral corrosion oral cavity, esophagus and stomach.Eye and skin contact can cause chemical burn.It is main To be used as solvent, curing agent, catalyst, cloudy poly- agent, preservative, and synthetic dyestuffs etc..It can be used as in organic synthesis industry molten Agent, catalyst and raw material.It can be used to produce the catalyst of phosgenation makrolon, the polymerization inhibitor of tetrafluoroethene, vulcanization of rubber rush Enter agent, special solvent, enamel anti-hardening agent in paint stripper, acid binding agent, surfactant, preservative, bactericide, ion exchange Resin, dyestuff, spices, medicine, high-energy fuel and liquid rocket propellant etc..

PE 9010 be Phenoxyethanol and Sensiva SC50 compounding liquid preservative used for cosmetic, Sensiva SC50 The surface tension on microbial cell film is have impact on, so as to improve the antiseptic power of Phenoxyethanol.PE 9010 be Phenoxyethanol and The liquid preservative used for cosmetic of Sensiva SC50 compounding, Sensiva SC50 have impact on the surface on microbial cell film Power, so as to improve the antiseptic power of Phenoxyethanol.There is the balanced inhibitory action of wide spectrum to bacterium, saccharomycete and mould, be one The typical antibacterial aseptic production of kind, while also there is certain sterilizing ability.PE9010 is highly stable, not facile hydrolysis.To temperature There is good tolerance with pH value.Its favorable solubility, even if can also be well dispersed in each system at low temperature.

The compound anti-acne factor is methyl propanediol, 4- terpineols, salicylic acid, white willow bark extract, and 4- terpineols are derived from Tea oil, there is broad-spectrum antiseptic, anti-inflammatory effect, property stabilization；White willow bark extract mainly contains polyphenol, flavones and bigcatkin willow Acid, can anti-inflammatory, antibacterial, Cress.The raw material has stronger specific aim to chlosma and propionibacterium acnes, available for Cuo Sore/acne, the active skull cap components of oily skin nursing.

Snake gall（Snake gall), it is the gall-bladder that bile is stored in snake body.Snake gall is cool in nature, bitter but slightly sweet taste；Removed with wind-dispelling The effect of miliaria is removed in wet, refrigerant improving eyesight, removing toxic substances；The adjustable nervous system for mending people, internal system and immune system, delay body to decline Always.All snake galls can all be used as medicine, particularly banked krait, Bungarus multicinctus, chessboard snake, cobra, king cobra, long-noded pit viper, pallas pit viper Courage, the valable starting materials being even more used as medicine.Contain abundant trace copper, iron, calcium, magnesium, injection Vitamin B_6 etc. in snake gall, they In safeguarding people's hormone in vivo and delaying the vital movements such as senility of humanbody, play an important role, often take snake gall, tune can be passed through Give sb. a hard time vivo environment, improve human body circulation, strengthen immunity, it is extremely good to reach the purpose effect controlled in outer disease.

Compared with the prior art the present invention, there is prominent substantive distinguishing features and significant progress to be：

1st, present invention addition natural disinfection composition, there is good bactericidal effect；The progress that can be enhanced metabolism, activating skin are thin Born of the same parents, for skin nutrition, skin is protected not corroded by bacterium；Can also antiallergic cream can dispel acne, promote facial blood circulation and skin Skin cytothesis, skin-tolerant is improved, reduce or eliminate the allergic reaction of skin；Improve the allergy tolerance of skin, safety Effectively.

2nd, the present invention reaches more than 98% for the effective percentage of anti-acne.

3rd, it is that the snake gall after drying in the shade is put in into microwave 1 minute in micro-wave oven that the present invention, which takes snake gall extract, takes out leaching Steep in 50 DEG C of hot water, constant temperature soaks 15 minutes, takes out the snake gall of water swelling, is put in the collector sterilized and by snake Courage punctures, and collects liquid；By the liquid it is purified, concentration, produce snake gall extract solution；Maximum can obtain snake gall it is effective into Point, play snake gall the effect of.

4th, the present invention can improve human body circulation, strengthen immunity, promote myogenic；Skin trauma can be effectively repaired, does not stay wound Scar；And can promotes skin blood circulation, can be to the effective toxin expelling of skin so that skin glow gloss.

5th, the present invention can adjust the nervous system for mending people, internal system and immune system, delay body aging.

6th, the present invention can adjust skin physiological environment, recover water and oil balance, suppress excess oil, while it is comprehensive to give skin Fine and smooth protection；Skin effective antiinflammatory and antibiotic effect can be strengthened the metabolism of acne print cutin, effective anti-acne, repair impaired acne flesh； Can be to skin-whitening beauty treatment.

Embodiment

It is to combine embodiments of the invention below, the present invention is described in detail：

Embodiment 1：

0.1 part of propyl p-hydroxybenzoate, 0.1 part of Methyl p-hydroxybenzoate, 0.3 part of 1618 alcohol, A165 are 1 part, GP-200 is 1 part, IPM 2 Part, 2 parts of saualane, DC-200 are 2 parts, the molten VE0.4 parts of oil, 0.04 part of borneol, 2 parts of 26# white oils, EDTA2Na are 0.04 part, urine 0.2 part of Bursin, card ripple 940 are 0.2 part, 2 parts of niacinamide, 6 parts of glycerine, 2 parts of propane diols, 70 parts of deionized water, TEA 0.2 Part, PE9010 are 0.3 part, 0.6 part of the compound anti-acne factor, 0.2 part of snake gall extract.

Above-described preparation method includes following steps：

（1）Propyl p-hydroxybenzoate, Methyl p-hydroxybenzoate, 1618 alcohol, A165, GP-200, IPM, saualane, DC-200 and the molten VE of oil are thrown Enter clean oil cauldron to dissolve by heating to 76 DEG C of degree；Add borneol and 26# white oils dissolve, homogeneous 2 minutes, obtain mixtures of materials A, constant temperature are standby；

（2）EDTA2Na, allantoin, card ripple 940, niacinamide, glycerine, propane diols and deionized water are put into clean emulsification pot 85 DEG C are heated with stirring to, homogeneous is completely dissolved no particle in 2 minutes to card ripple 940, obtains mixtures of materials B, standby；

（3）Mixtures of materials A and mixtures of materials B is pumped into emulsification pot and stirred 4 minutes, homogeneous 3 minutes, constant temperature disappears for 20 minutes Bubble, mixtures of materials C is obtained, it is standby；

（4）Mixtures of materials C is cooled, is down to 68 DEG C, TEA is added and stirs, homogeneous 3 minutes, obtains material mixing Thing D, constant temperature are standby；

（5）Mixtures of materials D is cooled, is down to 38 DEG C, adds PE9010, the compound anti-acne factor and snake gall extract Stir, homogeneous 3 minutes, coagulate frost, discharged after qualified to version, pack or bottling, produce snake gall anti-acne essence cream.

The preparation method of snake gall extract solution described above is：Snake gall after drying in the shade is put in microwave 1 minute in micro-wave oven, Taking-up is soaked in 50 DEG C of hot water, and constant temperature soaks 15 minutes, takes out the snake gall of water swelling, is put in the collector sterilized And puncture snake gall, collect liquid；By the liquid it is purified, concentration, produce snake gall extract solution.

Snake gall described above is cobra snake gall.

Embodiment 2：

0.6 part of propyl p-hydroxybenzoate, 0.6 part of Methyl p-hydroxybenzoate, 0.8 part of 1618 alcohol, A165 are 6 parts, GP-200 is 4 parts, IPM is 10 parts, 8 parts of saualane, DC-200 be 8 parts, the molten VE of oil is 1 part, 0.12 part of borneol, 8 parts of 26# white oils, EDTA2Na are 0.2 part, 1 part of allantoin, card ripple 940 are 1 part, 8 parts of niacinamide, 16 parts of glycerine, 14 parts of propane diols, 80 parts of deionized water, TEA 0.5 Part, PE9010 are 0.8 part, 2 parts of the compound anti-acne factor, 2 parts of snake gall extract.

Above-described preparation method includes following steps：

（1）Propyl p-hydroxybenzoate, Methyl p-hydroxybenzoate, 1618 alcohol, A165, GP-200, IPM, saualane, DC-200 and the molten VE of oil are thrown Enter clean oil cauldron to dissolve by heating to 82 DEG C of degree；Add borneol and 26# white oils dissolve, homogeneous 3 minutes, obtain mixtures of materials A, constant temperature are standby；

（2）EDTA2Na, allantoin, card ripple 940, niacinamide, glycerine, propane diols and deionized water are put into clean emulsification pot 90 DEG C are heated with stirring to, homogeneous is completely dissolved no particle in 3 minutes to card ripple 940, obtains mixtures of materials B, standby；

（3）Mixtures of materials A and mixtures of materials B is pumped into emulsification pot and stirred 6 minutes, homogeneous 5 minutes, constant temperature disappears for 24 minutes Bubble, mixtures of materials C is obtained, it is standby；

（4）Mixtures of materials C is cooled, is down to 72 DEG C, TEA is added and stirs, homogeneous 4 minutes, obtains material mixing Thing D, constant temperature are standby；

（5）Mixtures of materials D is cooled, is down to 42 degree, adds PE9010, the compound anti-acne factor and snake gall extract Stir, homogeneous 4 minutes, coagulate frost, discharged after qualified to version, pack or bottling, produce snake gall anti-acne essence cream.

The preparation method of snake gall extract solution described above is：Snake gall after drying in the shade is put in microwave 2 minutes in micro-wave oven, Taking-up is soaked in 60 DEG C of hot water, and constant temperature soaks 20 minutes, takes out the snake gall of water swelling, is put in the collector sterilized And puncture snake gall, collect liquid；By the liquid it is purified, concentration, produce snake gall extract solution.

Snake gall described above is zaocys dhumnade snake gall.

Embodiment 3：

0.35 part of propyl p-hydroxybenzoate, 0.35 part of Methyl p-hydroxybenzoate, 0.55 part of 1618 alcohol, A165 are 3.5 parts, GP-200 4.5 Part, IPM be 6 parts, 5 parts of saualane, DC-200 are 6 parts, the molten VE0.7 parts of oil, 0.08 part of borneol, 6 parts of 26# white oils, EDTA2Na are 0.12 part, 0.6 part of allantoin, card ripple 940 be 0.6 part, 5 parts of niacinamide, 11 parts of glycerine, 8 parts of propane diols, 75 parts of deionized water, TEA is 0.35 part, PE9010 is 0.55 part, 1.3 parts of the compound anti-acne factor, 1.1 parts of snake gall extract.

Above-described preparation method includes following steps：

（1）Propyl p-hydroxybenzoate, Methyl p-hydroxybenzoate, 1618 alcohol, A165, GP-200, IPM, saualane, DC-200 and the molten VE of oil are thrown Enter clean oil cauldron to dissolve by heating to 79 DEG C of degree；Add borneol and 26# white oils dissolve, homogeneous 2.5 minutes, obtain material mixing Thing A, constant temperature are standby；

（2）EDTA2Na, allantoin, card ripple 940, niacinamide, glycerine, propane diols and deionized water are put into clean emulsification pot 87 DEG C are heated with stirring to, homogeneous is completely dissolved no particle in 2.5 minutes to card ripple 940, obtains mixtures of materials B, standby；

（3）Mixtures of materials A and mixtures of materials B is pumped into emulsification pot and stirred 5 minutes, homogeneous 4 minutes, constant temperature disappears for 22 minutes Bubble, mixtures of materials C is obtained, it is standby；

（4）Mixtures of materials C is cooled, is down to 70 DEG C, TEA is added and stirs, homogeneous 3.5 minutes, material is obtained and mixes Compound D, constant temperature are standby；

（5）Mixtures of materials D is cooled, is down to 40 DEG C, adds PE9010, the compound anti-acne factor and snake gall extract Stir, homogeneous 3.5 minutes, coagulate frost, discharged after qualified to version, pack or bottling, produce snake gall anti-acne essence cream.

The preparation method of snake gall extract solution described above is：Snake gall after drying in the shade is put in into microwave 1.5 in micro-wave oven to divide Clock, taking-up are soaked in 55 DEG C of hot water, and constant temperature soaks 17 minutes, takes out the snake gall of water swelling, is put in the collection sterilized Punctured in device and by snake gall, collect liquid；By the liquid it is purified, concentration, produce snake gall extract solution.

Snake gall described above is adder snake gall.

Embodiment 4：

0.4 part of propyl p-hydroxybenzoate, 0.5 part of Methyl p-hydroxybenzoate, 0.6 part of 1618 alcohol, A165 are 4 parts, GP-200 is 5 parts, IPM 8 Part, 6 parts of saualane, DC-200 are 7 parts, the molten VE0.8 parts of oil, 0.1 part of borneol, 6 parts of 26# white oils, EDTA2Na are 0.14 part, urine 0.7 part of Bursin, card ripple 940 are 0.4 part, 5 parts of niacinamide, 12 parts of glycerine, 6 parts of propane diols, 76 parts of deionized water, TEA 0.4 Part, PE9010 are 0.6 part, 1.6 parts of the compound anti-acne factor, 1.2 parts of snake gall extract.

Above-described preparation method includes following steps：

（1）Propyl p-hydroxybenzoate, Methyl p-hydroxybenzoate, 1618 alcohol, A165, GP-200, IPM, saualane, DC-200 and the molten VE of oil are thrown Enter clean oil cauldron to dissolve by heating to 80 DEG C of degree；Add borneol and 26# white oils dissolve, homogeneous 3 minutes, obtain mixtures of materials A, constant temperature are standby；

（2）EDTA2Na, allantoin, card ripple 940, niacinamide, glycerine, propane diols and deionized water are put into clean emulsification pot 88 DEG C are heated with stirring to, homogeneous is completely dissolved no particle in 2 minutes to card ripple 940, obtains mixtures of materials B, standby；

（3）Mixtures of materials A and mixtures of materials B is pumped into emulsification pot and stirred 4 minutes, homogeneous 3 minutes, constant temperature disappears for 21 minutes Bubble, mixtures of materials C is obtained, it is standby；

（4）Mixtures of materials C is cooled, is down to 71 DEG C, TEA is added and stirs, homogeneous 4 minutes, obtains material mixing Thing D, constant temperature are standby；

（5）Mixtures of materials D is cooled, is down to 40 DEG C, adds PE9010, the compound anti-acne factor and snake gall extract Stir, homogeneous 4 minutes, coagulate frost, discharged after qualified to version, pack or bottling, produce snake gall anti-acne essence cream.

The preparation method of snake gall extract solution described above is：Snake gall after drying in the shade is put in microwave 2 minutes in micro-wave oven, Taking-up is soaked in 56 DEG C of hot water, and constant temperature soaks 18 minutes, takes out the snake gall of water swelling, is put in the collector sterilized And puncture snake gall, collect liquid；By the liquid it is purified, concentration, produce snake gall extract solution.

Snake gall described above is pallas pit viper snake gall.

Above-described embodiment using effect

Start within -2017 years 2015 to try out snake gall anti-acne essence cream of the present invention in Hengxian County, the people of volunteer 50, volunteer has white The symptoms such as head, blackhead, inflamed papules, warts, using snake gall anti-acne essence cream of the present invention, 2 times a day, once in the morning and once at night, General 1~2 course for the treatment of takes effect, and 2~3 courses for the treatment of turn for the better by and large, 4~5 basic rehabilitations of the course for the treatment of, and each course for the treatment of is 7 days, efficient Reach more than 98%.

Application method：Warm water cleaning face, then snake gall anti-acne essence cream of the present invention is uniformly applied in face, and gently It is massaged into and fully absorbs.

Snake gall anti-acne essence cream of the present invention was treated to 50 cases altogether from 2015 to 2017, and the effect for the treatment of is such as Following table：

Table 1 is the anti-acne efficacy result of snake gall anti-acne essence cream of the present invention

Group name	Treatment number	Cure	It is invalid	Total effective rate
					Treatment group	50	49	1	98%

Pass through table 1, it is seen that snake gall anti-acne essence cream of the present invention is to the efficient up to 98% of beautifying face and moistering lotion.

Clinical practice embodiment：

Case 1

Wei XX, man, 17 years old, Guangxi Zhuang Autonomous Region people from Heng County, on the face with the red point of hoary hair, household was thought as whelk, but more Length is more, and it is allergic dermatitis to remove patient diagnosis；Return to treat by medicine, eliminate most, but leave black dull acne print, can not remove, Introduce using the snake gall anti-acne essence cream obtained by the embodiment of the present invention 1 by other people, twice daily, once in the morning and once at night, use Complete first course for the treatment of, original acne to disappear, also eliminate, and do not left acne print, and original black dull acne print is thin out；Reuse one The individual course for the treatment of, the black dull thin out many of acne print；A course for the treatment of is continuing with, black dull acne print eliminates, and skin Lightening is ruddy.

Case 2

Deep XX, female, 25 years old, often there was acne in Guangxi Zhuang Autonomous Region people from Heng County, face, again long after a period of time that just disappeared, and also flowed down big Small multiple acne print pit acne prints for differing are deeper, and dull gray, and good efficacy is not all played using cosmetics and medicine；Use this hair Snake gall anti-acne essence cream obtained by bright embodiment 2, twice daily, once in the morning and once at night, after a course for the treatment of, it is former with acne Eliminate, the acne print of dull gray is more thin out, reuses a course for the treatment of, and acne print is effectively repaired, before acne print depth relative usage Shoal, also have some dull grays, be continuing with a course for the treatment of, dull gray color eliminates, and acne print becomes more shallow；It is further continued for using one The individual course for the treatment of, skin Lightening is ruddy, and pit acne print is substantially repaired；A course for the treatment of is continuing with, pit acne print eliminates, and skin is white It is net ruddy；Snake gall anti-acne essence cream of the present invention brings beautiful and confidence to her, can adhere to being continuing with.

Case 3

Old XX, female, 30 years old, Guangxi Zhuang Autonomous Region people from Heng County, face's blackhead, there is blackening so that face has aberration, makes Could not also solve the problems, such as her with other cosmetics, be that she enjoys puzzlement, people becomes to feel oneself inferior, and smile tails off；Afterwards using the present invention Snake gall anti-acne essence cream obtained by embodiment 3,2 times a day, once in the morning and once at night, after a course for the treatment of, face's acne are obvious Tailing off, blackening is somewhat thin out, reuses a course for the treatment of, and face's acne have eliminated, and with respect to first course for the treatment of of blackening is thin out a lot, after It is continuous use a course for the treatment of, blackening thin out many, a course for the treatment of is continuing with, blackening eliminates most, the original color of face Difference sense substantially dies down, and the colour of skin is basically identical；It is further continued for using a course for the treatment of, skin is fair and clear ruddy, and the colour of skin is consistent；Using Cheng Zhong, she does not also feel there is any discomfort, and she enjoys a lot herself, thoroughly solves her worry, and beauty is brought to her.

Case 4

Old XX, man, 32 years old, Guangxi Zhuang Autonomous Region people from Heng County was drunk to tumble by motorcycle, caused face red and swollen, red through treating Swollen to eliminate, both sides but leave the red color spot of dull gray, curative effect are not also played using other cosmetics；Introduced by other people and use this Snake gall anti-acne essence cream obtained by inventive embodiments 4, once in the morning and once at night, after a course for the treatment of, color spot is thin out, is continuing with One course for the treatment of, color spot is thin out to diminish, and after reusing a course for the treatment of, color spot is thin out more, and area reduces many, is continuing with a treatment Cheng Hou, color spot substantially eliminate；It is further continued for using after a course for the treatment of, color spot thoroughly eliminates, and skin is ruddy fair and clear.

Case 5

Blue XX, female, 22 years old, Guangxi Zhuang Autonomous Region people from Heng County, the long inflamed papules of face, using obtained by the embodiment of the present invention 2 Snake gall anti-acne essence cream, once in the morning and once at night, after a course for the treatment of, papule is effectively controlled, so not red；Continue After a course for the treatment of, papule substantially tails off, and scar is not left at the papule position of elimination；It is further continued for after using a course for the treatment of, mound Rash is changed into fragmentary several, and red very light, scar is not also left at the papule position of elimination；After being continuing with a course for the treatment of, skin is white Net glossy, papule is thoroughly fully recovered.

Case 6

Clock XX, female, 28 years old, Guangxi Zhuang Autonomous Region people from Heng County, face disappeared with warts, crowded one, but leaves dull gray spot, And grown again at another position, she enjoys puzzlement and sad, can not all work contentedly for this, be introduced by other people and use this Snake gall anti-acne essence cream obtained by inventive embodiments 3, once in the morning and once at night, after a course for the treatment of, during which come to a head without newly length Blister, original warts red is thin out, and individual diminishes, and original dull gray spot is thin out；After being continuing with a course for the treatment of, warts does not have yet Newly grow, original warts red becomes lighter, and individual more diminishes, original thin out many of dull gray spot；It is further continued for using one After the course for the treatment of, warts is changed into grain of rice size, not red, and original dull gray spot eliminates；After being continuing with a course for the treatment of, skin is fair and clear to be had Gloss, warts are thoroughly fully recovered.

Claims

A kind of 1. snake gall anti-acne essence cream, it is characterised in that：Its active ingredient is to be prepared from the following raw materials in parts by weight：

0.1~0.6 part of propyl p-hydroxybenzoate

0.1~0.6 part of Methyl p-hydroxybenzoate

1618 0.3~0.8 part of alcohol

1~6 part of A165

1~4 part of GP-200

2~10 parts of IPM

2~8 parts of saualane

2~8 parts of DC-200

Molten 0.4~1 part of the VE of oil

0.04~0.12 part of borneol

2~8 parts of 26# white oils

EDTA2Na0.04~0.2 part

0.2~1 part of allantoin

940 0.2~1 part of card ripple

2~8 parts of niacinamide PC

6~16 parts of glycerine

2~14 parts of propane diols

70~80 parts of deionized water

0.2~0.5 part of TEA

0.3~0.8 part of PE9010

Compound 0.6~2 part of the anti-acne factor

0.2~2 part of snake gall extract.
2. snake gall anti-acne essence cream according to claim 1, it is characterised in that described preparation method includes following Step：

（1）Propyl p-hydroxybenzoate, Methyl p-hydroxybenzoate, 1618 alcohol, A165, GP-200, IPM, saualane, DC-200 and the molten VE of oil are thrown Enter clean oil cauldron to dissolve by heating to 76~82 DEG C of degree；Add borneol and 26# white oils dissolve, homogeneous 2~3 minutes, obtain material Mixture A, constant temperature are standby；

（2）EDTA2Na, allantoin, card ripple 940, niacinamide, glycerine, propane diols and deionized water are put into clean emulsification pot 85~90 DEG C are heated with stirring to, homogeneous is completely dissolved no particle in 2~3 minutes to card ripple 940, obtains mixtures of materials B, standby；

（3）Mixtures of materials A and mixtures of materials B is pumped into emulsification pot and stirred 4~6 minutes, homogeneous 3~5 minutes, constant temperature 20 Defoam within~24 minutes, obtain mixtures of materials C, it is standby；

（4）Mixtures of materials C is cooled, is down to 68~72 DEG C, TEA is added and stirs, homogeneous 3~4 minutes, obtains thing Material mixture D, constant temperature are standby；

（5）Mixtures of materials D is cooled, is down to 38~42 DEG C, PE9010, the compound anti-acne factor and snake gall is added and carries Take thing to stir, homogeneous 3~4 minutes, coagulate frost, discharged after qualified to version, pack or bottling, produce snake gall anti-acne essence cream.
3. snake gall anti-acne essence cream according to claim 2, it is characterised in that：The loss of each step in the preparation method Water presses 2% addition per step material gross weight.
4. snake gall anti-acne essence cream according to claim 1 or 2, it is characterised in that the preparation side of the snake gall extract solution Method is：Snake gall after drying in the shade is put in microwave 1~2 minute in micro-wave oven, taking-up is soaked in 50~60 DEG C of hot water, constant temperature Immersion 15~20 minutes, the snake gall of water swelling is taken out, be put in the collector sterilized and puncture snake gall, collect liquid； By the liquid it is purified, concentration, produce snake gall extract solution.
5. snake gall anti-acne essence cream according to claim 1 or 2, it is characterised in that：The snake gall is cobra snake gall, crow It is a kind of in tip calmy courage, Bungarus multicinctus snake gall, pallas pit viper snake gall, banked krait snake gall, king cobra snake gall or adder snake gall.